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Ning Zheng, Ph.D. - Publications

Affiliations: 
Pharmacology University of Washington/HHMI 
Area:
Ubquitin
Website:
http://depts.washington.edu/zhenglab/
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90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Dahlin HR, Zheng N, Scott JD. Beyond PKA: Evolutionary and Structural Insights that Define a Docking and Dimerization Domain Superfamily. The Journal of Biological Chemistry. 100927. PMID 34256050 DOI: 10.1016/j.jbc.2021.100927  0.31
2021 Dahlin HR, Zheng N, Scott JD. Beyond PKA: Evolutionary and Structural Insights that Define a Docking and Dimerization Domain Superfamily. The Journal of Biological Chemistry. 100927. PMID 34256050 DOI: 10.1016/j.jbc.2021.100927  0.31
2020 Wang W, Withers J, Li H, Zwack PJ, Rusnac DV, Shi H, Liu L, Yan S, Hinds TR, Guttman M, Dong X, Zheng N. Structural basis of salicylic acid perception by Arabidopsis NPR proteins. Nature. PMID 32788727 DOI: 10.1038/S41586-020-2596-Y  0.434
2020 Fribourgh JL, Srivastava A, Sandate CR, Michael AK, Hsu PL, Rakers C, Nguyen LT, Torgrimson MR, Parico GCG, Tripathi S, Zheng N, Lander GC, Hirota T, Tama F, Partch CL. Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing. Elife. 9. PMID 32101164 DOI: 10.7554/Elife.55275  0.349
2020 Fan J, Petersen EM, Hinds TR, Zheng N, Miller SI. Structure of an Inner Membrane Protein Required for PhoPQ-Regulated Increases in Outer Membrane Cardiolipin. Mbio. 11. PMID 32047135 DOI: 10.1128/Mbio.03277-19  0.351
2020 Lin H, Zhang X, Liu L, Fu Q, Zang C, Ding Y, Su Y, Xu Z, He S, Yang X, Wei X, Mao H, Cui Y, Wei Y, Zhou C, ... ... Zheng N, et al. Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome. Proceedings of the National Academy of Sciences of the United States of America. PMID 32047038 DOI: 10.1073/Pnas.1911998117  0.413
2020 Gutierrez C, Chemmama IE, Mao H, Yu C, Echeverria I, Block SA, Rychnovsky SD, Zheng N, Sali A, Huang L. Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling. Proceedings of the National Academy of Sciences of the United States of America. PMID 32034103 DOI: 10.1073/Pnas.1915542117  0.382
2020 Rusnac DV, Zheng N. Structural Biology of CRL Ubiquitin Ligases. Advances in Experimental Medicine and Biology. 1217: 9-31. PMID 31898219 DOI: 10.1007/978-981-15-1025-0_2  0.44
2019 Jiang D, Shi H, Tonggu L, Gamal El-Din TM, Lenaeus MJ, Zhao Y, Yoshioka C, Zheng N, Catterall WA. Structure of the Cardiac Sodium Channel. Cell. PMID 31866066 DOI: 10.1016/J.Cell.2019.11.041  0.302
2019 Hsu PL, Shi H, Leonen C, Kang J, Chatterjee C, Zheng N. Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS. Molecular Cell. PMID 31733991 DOI: 10.1016/J.Molcel.2019.10.013  0.341
2019 Janezic EM, Harris DA, Dinh D, Lee KS, Stewart A, Hinds TR, Hsu PL, Zheng N, Hague C. Scribble co-operatively binds multiple α-adrenergic receptor C-terminal PDZ ligands. Scientific Reports. 9: 14073. PMID 31575922 DOI: 10.1038/S41598-019-50671-6  0.376
2019 Canzani D, Rusnac DV, Zheng N, Bush MF. Degronomics: Mapping the Interacting Peptidome of a Ubiquitin Ligase Using an Integrative Mass Spectrometry Strategy. Analytical Chemistry. PMID 31525912 DOI: 10.1021/Acs.Analchem.9B02331  0.344
2019 Putarjunan A, Ruble J, Srivastava A, Zhao C, Rychel AL, Hofstetter AK, Tang X, Zhu JK, Tama F, Zheng N, Torii KU. Bipartite anchoring of SCREAM enforces stomatal initiation by coupling MAP kinases to SPEECHLESS. Nature Plants. PMID 31235876 DOI: 10.1038/S41477-019-0440-X  0.43
2019 Kuchay S, Wang H, Marzio A, Jain K, Homer H, Fehrenbacher N, Philips MR, Zheng N, Pagano M. GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase. Nature Structural & Molecular Biology. PMID 31209342 DOI: 10.1038/S41594-019-0249-3  0.405
2018 Shabek N, Ruble J, Waston CJ, Garbutt KC, Hinds TR, Li T, Zheng N. Structural insights into DDA1 function as a core component of the CRL4-DDB1 ubiquitin ligase. Cell Discovery. 4: 67. PMID 30564455 DOI: 10.1038/S41421-018-0064-8  0.708
2018 Rusnac DV, Lin HC, Canzani D, Tien KX, Hinds TR, Tsue AF, Bush MF, Yen HS, Zheng N. Recognition of the Diglycine C-End Degron by CRL2 Ubiquitin Ligase. Molecular Cell. 72: 813-822.e4. PMID 30526872 DOI: 10.1016/J.Molcel.2018.10.021  0.375
2018 Gamal El-Din TM, Lenaeus MJ, Ramanadane K, Zheng N, Catterall WA. Molecular dissection of multiphase inactivation of the bacterial sodium channel NaAb. The Journal of General Physiology. PMID 30510035 DOI: 10.1085/Jgp.201711884  0.311
2018 Shabek N, Ticchiarelli F, Mao H, Hinds TR, Leyser O, Zheng N. Structural plasticity of D3-D14 ubiquitin ligase in strigolactone signalling. Nature. PMID 30464344 DOI: 10.2210/Pdb6Brp/Pdb  0.711
2018 Hsu PL, Li H, Lau HT, Leonen C, Dhall A, Ong SE, Chatterjee C, Zheng N. Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module. Cell. PMID 30100181 DOI: 10.1016/J.Cell.2018.06.038  0.376
2018 Lin HC, Yeh CW, Chen YF, Lee TT, Hsieh PY, Rusnac DV, Lin SY, Elledge SJ, Zheng N, Yen HS. C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases. Molecular Cell. 70: 602-613.e3. PMID 29775578 DOI: 10.1016/J.Molcel.2018.04.006  0.533
2018 Curran EC, Wang H, Hinds TR, Zheng N, Wang EH. Zinc knuckle of TAF1 is a DNA binding module critical for TFIID promoter occupancy. Scientific Reports. 8: 4630. PMID 29545534 DOI: 10.1038/S41598-018-22879-5  0.386
2018 Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Ponnienselvan K, Liu JC, Parmar K, Zheng N, D'Andrea A. Abstract 333: USP1 is required for replication fork stability in BRCA1-deficient tumors Cancer Research. 78: 333-333. DOI: 10.1158/1538-7445.Am2018-333  0.316
2017 Zheng N, Shabek N. Ubiquitin Ligases: Structure, Function, and Regulation. Annual Review of Biochemistry. PMID 28375744 DOI: 10.1146/Annurev-Biochem-060815-014922  0.743
2017 Lenaeus MJ, Gamal El-Din TM, Ing C, Ramanadane K, Pomès R, Zheng N, Catterall WA. Structures of closed and open states of a voltage-gated sodium channel. Proceedings of the National Academy of Sciences of the United States of America. PMID 28348242 DOI: 10.1073/Pnas.1700761114  0.333
2017 Gamal El-Din TM, Lenaeus MJ, Ramanadane K, Zheng N, Catterall WA. Control of Slow, Use Dependent Inactivation of Na V Ab by its C Terminal Tail Biophysical Journal. 112: 105a. DOI: 10.1016/J.Bpj.2016.11.597  0.31
2016 Gallego LD, Ghodgaonkar Steger M, Polyansky AA, Schubert T, Zagrovic B, Zheng N, Clausen T, Herzog F, Köhler A. Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601672 DOI: 10.1073/Pnas.1606863113  0.393
2016 Tang L, El-Din TM, Swanson TM, Pryde DC, Scheuer T, Zheng N, Catterall WA. Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature. PMID 27556947 DOI: 10.1038/Nature19102  0.321
2016 Li H, Lim KS, Kim H, Hinds TR, Jo U, Mao H, Weller CE, Sun J, Chatterjee C, D'Andrea AD, Zheng N. Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20. Molecular Cell. PMID 27373336 DOI: 10.1016/J.Molcel.2016.05.031  0.545
2016 Laha D, Parvin N, Dynowski M, Johnen P, Mao H, Bitters ST, Zheng N, Schaaf G. Inositol polyphosphate binding specificity of the jasmonate receptor complex. Plant Physiology. PMID 27288364 DOI: 10.1104/Pp.16.00694  0.322
2016 Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka IR. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nature Communications. 7: 11742. PMID 27230261 DOI: 10.1038/Ncomms11742  0.37
2016 Wu K, Chong RA, Yu Q, Bai J, Spratt DE, Ching K, Lee C, Miao H, Tappin I, Hurwitz J, Zheng N, Shaw GS, Sun Y, Felsenfeld DP, Sanchez R, et al. Suramin inhibits cullin-RING E3 ubiquitin ligases. Proceedings of the National Academy of Sciences of the United States of America. PMID 27001857 DOI: 10.1073/Pnas.1601089113  0.379
2016 Scherer PC, Ding Y, Liu Z, Xu J, Mao H, Barrow JC, Wei N, Zheng N, Snyder SH, Rao F. Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976604 DOI: 10.1073/Pnas.1525580113  0.42
2016 Zhou F, Lin Q, Zhu L, Ren Y, Zhou K, Shabek N, Wu F, Mao H, Dong W, Gan L, Ma W, Gao H, Chen J, Yang C, Wang D, ... Zheng N, et al. Corrigendum: D14-SCF(D3)-dependent degradation of D53 regulates strigolactone signalling. Nature. PMID 26760207 DOI: 10.1038/Nature16537  0.701
2016 El-Din TMG, Swanson TM, Tang L, Zheng N, Catterall WA. Functional and Molecular Interaction of Phenylalkylamines and Dihydropyridines with the Model Calcium Channel CavAb Biophysical Journal. 110: 440a. DOI: 10.1016/J.Bpj.2015.11.2370  0.32
2015 Sun J, Zheng N. Molecular Mechanism Underlying the Plant NRT1.1 Dual-Affinity Nitrate Transporter. Frontiers in Physiology. 6: 386. PMID 26733879 DOI: 10.3389/Fphys.2015.00386  0.493
2015 Yu C, Mao H, Novitsky EJ, Tang X, Rychnovsky SD, Zheng N, Huang L. Gln40 deamidation blocks structural reconfiguration and activation of SCF ubiquitin ligase complex by Nedd8. Nature Communications. 6: 10053. PMID 26632597 DOI: 10.1038/Ncomms10053  0.419
2015 Catterall WA, Zheng N. Deciphering voltage-gated Na(+) and Ca(2+) channels by studying prokaryotic ancestors. Trends in Biochemical Sciences. PMID 26254514 DOI: 10.1016/J.Tibs.2015.07.002  0.348
2015 Moss BL, Mao H, Guseman JM, Hinds TR, Hellmuth A, Kovenock M, Noorassa A, Lanctot A, Calderon Villalobos LI, Zheng N, Nemhauser J. Rate motifs tune Aux/IAA degradation dynamics. Plant Physiology. PMID 26149575 DOI: 10.1104/Pp.15.00587  0.379
2015 Laha D, Johnen P, Azevedo C, Dynowski M, Weiß M, Capolicchio S, Mao H, Iven T, Steenbergen M, Freyer M, Gaugler P, de Campos MK, Zheng N, Feussner I, Jessen HJ, et al. VIH2 Regulates the Synthesis of Inositol Pyrophosphate InsP8 and Jasmonate-Dependent Defenses in Arabidopsis. The Plant Cell. 27: 1082-97. PMID 25901085 DOI: 10.1105/Tpc.114.135160  0.432
2014 Wang H, Curran EC, Hinds TR, Wang EH, Zheng N. Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module. Cell Research. 24: 1433-44. PMID 25412659 DOI: 10.1038/Cr.2014.148  0.444
2014 Nangle SN, Rosensweig C, Koike N, Tei H, Takahashi JS, Green CB, Zheng N. Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex. Elife. 3: e03674. PMID 25127877 DOI: 10.7554/Elife.03674  0.427
2014 Shabek N, Zheng N. Plant ubiquitin ligases as signaling hubs. Nature Structural & Molecular Biology. 21: 293-6. PMID 24699076 DOI: 10.1038/Nsmb.2804  0.726
2014 Sun J, Bankston JR, Payandeh J, Hinds TR, Zagotta WN, Zheng N. Crystal structure of the plant dual-affinity nitrate transporter NRT1.1. Nature. 507: 73-7. PMID 24572362 DOI: 10.1038/Nature13074  0.723
2014 Hast BE, Cloer EW, Goldfarb D, Li H, Siesser PF, Yan F, Walter V, Zheng N, Hayes DN, Major MB. Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination. Cancer Research. 74: 808-17. PMID 24322982 DOI: 10.1158/0008-5472.Can-13-1655  0.314
2013 Zhou F, Lin Q, Zhu L, Ren Y, Zhou K, Shabek N, Wu F, Mao H, Dong W, Gan L, Ma W, Gao H, Chen J, Yang C, Wang D, ... Zheng N, et al. D14-SCF(D3)-dependent degradation of D53 regulates strigolactone signalling. Nature. 504: 406-10. PMID 24336215 DOI: 10.1038/Nature12878  0.716
2013 Welcker M, Larimore EA, Swanger J, Bengoechea-Alonso MT, Grim JE, Ericsson J, Zheng N, Clurman BE. Fbw7 dimerization determines the specificity and robustness of substrate degradation. Genes & Development. 27: 2531-6. PMID 24298052 DOI: 10.1101/Gad.229195.113  0.386
2013 Nangle S, Xing W, Zheng N. Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase. Cell Research. 23: 1417-9. PMID 24080726 DOI: 10.1038/Cr.2013.136  0.537
2013 Zhao B, Zhang K, Bhuripanyo K, Choi CH, Villhauer EB, Li H, Zheng N, Kiyokawa H, Schindelin H, Yin J. Profiling the cross reactivity of ubiquitin with the Nedd8 activating enzyme by phage display. Plos One. 8: e70312. PMID 23936405 DOI: 10.1371/Journal.Pone.0070312  0.369
2013 Xing W, Busino L, Hinds TR, Marionni ST, Saifee NH, Bush MF, Pagano M, Zheng N. SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket. Nature. 496: 64-8. PMID 23503662 DOI: 10.1038/Nature11964  0.629
2012 Calderón Villalobos LI, Lee S, De Oliveira C, Ivetac A, Brandt W, Armitage L, Sheard LB, Tan X, Parry G, Mao H, Zheng N, Napier R, Kepinski S, Estelle M. A combinatorial TIR1/AFB-Aux/IAA co-receptor system for differential sensing of auxin. Nature Chemical Biology. 8: 477-85. PMID 22466420 DOI: 10.1038/Nchembio.926  0.56
2012 Shyu C, Figueroa P, Depew CL, Cooke TF, Sheard LB, Moreno JE, Katsir L, Zheng N, Browse J, Howe GA. JAZ8 lacks a canonical degron and has an EAR motif that mediates transcriptional repression of jasmonate responses in Arabidopsis. The Plant Cell. 24: 536-50. PMID 22327740 DOI: 10.1105/Tpc.111.093005  0.402
2012 Camp ND, James RG, Dawson DW, Yan F, Davison JM, Houck SA, Tang X, Zheng N, Major MB, Moon RT. Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein. The Journal of Biological Chemistry. 287: 6539-50. PMID 22215675 DOI: 10.1074/Jbc.M111.316471  0.402
2011 Roberts D, Pedmale UV, Morrow J, Sachdev S, Lechner E, Tang X, Zheng N, Hannink M, Genschik P, Liscum E. Modulation of phototropic responsiveness in Arabidopsis through ubiquitination of phototropin 1 by the CUL3-Ring E3 ubiquitin ligase CRL3(NPH3). The Plant Cell. 23: 3627-40. PMID 21990941 DOI: 10.1105/Tpc.111.087999  0.352
2011 Payandeh J, Scheuer T, Zheng N, Catterall WA. The crystal structure of a voltage-gated sodium channel. Nature. 475: 353-8. PMID 21743477 DOI: 10.1038/Nature10238  0.311
2011 Duda DM, Scott DC, Calabrese MF, Zimmerman ES, Zheng N, Schulman BA. Structural regulation of cullin-RING ubiquitin ligase complexes. Current Opinion in Structural Biology. 21: 257-64. PMID 21288713 DOI: 10.1016/J.Sbi.2011.01.003  0.621
2010 Sheard LB, Tan X, Mao H, Withers J, Ben-Nissan G, Hinds TR, Kobayashi Y, Hsu FF, Sharon M, Browse J, He SY, Rizo J, Howe GA, Zheng N. Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor. Nature. 468: 400-5. PMID 20927106 DOI: 10.1038/Nature09430  0.57
2010 Zimmerman ES, Schulman BA, Zheng N. Structural assembly of cullin-RING ubiquitin ligase complexes. Current Opinion in Structural Biology. 20: 714-21. PMID 20880695 DOI: 10.1016/J.Sbi.2010.08.010  0.636
2010 Cui J, Yao Q, Li S, Ding X, Lu Q, Mao H, Liu L, Zheng N, Chen S, Shao F. Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. Science (New York, N.Y.). 329: 1215-8. PMID 20688984 DOI: 10.1126/Science.1193844  0.371
2010 Aghajan M, Jonai N, Flick K, Fu F, Luo M, Cai X, Ouni I, Pierce N, Tang X, Lomenick B, Damoiseaux R, Hao R, Del Moral PM, Verma R, Li Y, ... ... Zheng N, et al. Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nature Biotechnology. 28: 738-42. PMID 20581845 DOI: 10.1038/Nbt.1645  0.387
2010 Calderon-Villalobos LI, Tan X, Zheng N, Estelle M. Auxin perception--structural insights. Cold Spring Harbor Perspectives in Biology. 2: a005546. PMID 20504967 DOI: 10.1101/Cshperspect.A005546  0.591
2010 Köhler A, Zimmerman E, Schneider M, Hurt E, Zheng N. Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module. Cell. 141: 606-17. PMID 20434206 DOI: 10.1016/J.Cell.2010.04.026  0.438
2010 Li T, Robert EI, van Breugel PC, Strubin M, Zheng N. A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nature Structural & Molecular Biology. 17: 105-11. PMID 19966799 DOI: 10.1038/Nsmb.1719  0.434
2009 Sharon M, Mao H, Boeri Erba E, Stephens E, Zheng N, Robinson CV. Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality. Structure (London, England : 1993). 17: 31-40. PMID 19141280 DOI: 10.1016/J.Str.2008.10.012  0.369
2009 Tan X, Zheng N. Hormone signaling through protein destruction: a lesson from plants. American Journal of Physiology. Endocrinology and Metabolism. 296: E223-7. PMID 19050175 DOI: 10.1152/Ajpendo.90807.2008  0.592
2008 Saifee NH, Zheng N. A ubiquitin-like protein unleashes ubiquitin ligases. Cell. 135: 209-11. PMID 18957195 DOI: 10.1016/J.Cell.2008.09.049  0.396
2008 Hayashi K, Tan X, Zheng N, Hatate T, Kimura Y, Kepinski S, Nozaki H. Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 5632-7. PMID 18391211 DOI: 10.1073/Pnas.0711146105  0.572
2007 Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT. Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. Science (New York, N.Y.). 316: 1043-6. PMID 17510365 DOI: 10.1126/Science/1141515  0.557
2007 Tan X, Calderon-Villalobos LI, Sharon M, Zheng C, Robinson CV, Estelle M, Zheng N. Mechanism of auxin perception by the TIR1 ubiquitin ligase. Nature. 446: 640-5. PMID 17410169 DOI: 10.1038/Nature05731  0.592
2007 Zheng N, Pavletich NP. The Structural Biology of Ubiquitin-Protein Ligases Protein Degradation. 1: 156-189. DOI: 10.1002/352760586X.Ch7  0.665
2006 Angers S, Li T, Yi X, MacCoss MJ, Moon RT, Zheng N. Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature. 443: 590-3. PMID 16964240 DOI: 10.1038/Nature05175  0.459
2006 Chen H, Shen Y, Tang X, Yu L, Wang J, Guo L, Zhang Y, Zhang H, Feng S, Strickland E, Zheng N, Deng XW. Arabidopsis CULLIN4 Forms an E3 Ubiquitin Ligase with RBX1 and the CDD Complex in Mediating Light Control of Development. The Plant Cell. 18: 1991-2004. PMID 16844902 DOI: 10.1105/Tpc.106.043224  0.373
2006 Chen X, Zhang J, Lee J, Lin PS, Ford JM, Zheng N, Zhou P. A kinase-independent function of c-Abl in promoting proteolytic destruction of damaged DNA binding proteins. Molecular Cell. 22: 489-99. PMID 16713579 DOI: 10.1016/J.Molcel.2006.04.021  0.339
2006 Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT. The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation. Nature Cell Biology. 8: 348-57. PMID 16547521 DOI: 10.1038/Ncb1381  0.594
2006 Li T, Chen X, Garbutt KC, Zhou P, Zheng N. Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell. 124: 105-17. PMID 16413485 DOI: 10.1016/J.Cell.2005.10.033  0.424
2005 Rubin SM, Gall AL, Zheng N, Pavletich NP. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell. 123: 1093-106. PMID 16360038 DOI: 10.1016/J.Cell.2005.09.044  0.737
2005 Li T, Pavletich NP, Schulman BA, Zheng N. High-level expression and purification of recombinant SCF ubiquitin ligases Methods in Enzymology. 398: 125-142. PMID 16275325 DOI: 10.1016/S0076-6879(05)98012-9  0.747
2005 Hao B, Zheng N, Schulman BA, Wu G, Miller JJ, Pagano M, Pavletich NP. Structural basis of the Cks1-dependent recognition of p27 Kip1 by the SCF Skp2 ubiquitin ligase Molecular Cell. 20: 9-19. PMID 16209941 DOI: 10.1016/J.Molcel.2005.09.003  0.724
2005 Martinez SE, Bruder S, Schultz A, Zheng N, Schultz JE, Beavo JA, Linder JU. Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: modes of ligand binding and dimerization. Proceedings of the National Academy of Sciences of the United States of America. 102: 3082-7. PMID 15708973 DOI: 10.1073/Pnas.0409913102  0.391
2005 Bruder S, Linder JU, Martinez SE, Zheng N, Beavo JA, Schultz JE. The cyanobacterial tandem GAF domains from the cyaB2 adenylyl cyclase signal via both cAMP-binding sites. Proceedings of the National Academy of Sciences of the United States of America. 102: 3088-92. PMID 15708972 DOI: 10.1073/Pnas.0409917102  0.375
2004 Goldenberg SJ, Cascio TC, Shumway SD, Garbutt KC, Liu J, Xiong Y, Zheng N. Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases. Cell. 119: 517-28. PMID 15537541 DOI: 10.1016/J.Cell.2004.10.019  0.656
2003 Zhang J, Zheng N, Zhou P. Exploring the functional complexity of cellular proteins by protein knockout. Proceedings of the National Academy of Sciences of the United States of America. 100: 14127-32. PMID 14593203 DOI: 10.1073/Pnas.2233012100  0.379
2003 Zheng N. A closer look of the HECTic ubiquitin ligases. Structure (London, England : 1993). 11: 5-6. PMID 12517333 DOI: 10.1016/S0969-2126(02)00940-1  0.384
2002 Yang H, Jeffrey PD, Miller J, Kinnucan E, Sun Y, Thomä NH, Zheng N, Chen PL, Lee WH, Pavletich NP. BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure Science. 297: 1837-1848. PMID 12228710 DOI: 10.1126/Science.297.5588.1837  0.744
2002 Dong Z, Zhao G, Zhao Q, Yang H, Xue L, Tan X, Zheng N. [A study of DNA polymerase beta mutation in human esophageal cancer]. Zhonghua Yi Xue Za Zhi. 82: 899-902. PMID 12126515  0.351
2002 Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex Nature. 416: 703-709. PMID 11961546 DOI: 10.1038/416703A  0.78
2001 Cleverley RM, Zheng N, Gierasch LM. The cost of exposing a hydrophobic loop and implications for the functional role of 4.5 S RNA in the Escherichia coli signal recognition particle. The Journal of Biological Chemistry. 276: 19327-31. PMID 11278844 DOI: 10.1074/Jbc.M011130200  0.772
2000 Zheng N, Wang P, Jeffrey PD, Pavletich NP. Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases Cell. 102: 533-539. PMID 10966114 DOI: 10.1016/S0092-8674(00)00057-X  0.671
1999 Zheng N, Fraenkel E, Pabo CO, Pavletich NP. Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes & Development. 13: 666-74. PMID 10090723 DOI: 10.1101/Gad.13.6.666  0.757
1997 Zheng N, Gierasch LM. Domain interactions in E. coli SRP: stabilization of M domain by RNA is required for effective signal sequence modulation of NG domain. Molecular Cell. 1: 79-87. PMID 9659905 DOI: 10.1016/S1097-2765(00)80009-X  0.565
1996 Zheng N, Gierasch LM. Signal sequences: the same yet different. Cell. 86: 849-52. PMID 8808619 DOI: 10.1016/S0092-8674(00)80159-2  0.511
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