Gencheng Li
Affiliations: | The Scripps Reserach Institute, Scripps Florida |
Area:
organic chemistryGoogle:
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Publications
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| Yang B, Sukheja P, Qin B, et al. (2023) Synthesis and structure-activity relationships of aryl fluorosulfate-based inhibitors as novel antitubercular agents. Bioorganic & Medicinal Chemistry Letters. 98: 129596 |
| Cheng Y, Li G, Smedley CJ, et al. (2022) Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208540119 |
| Li S, Li G, Gao B, et al. (2021) SuFExable polymers with helical structures derived from thionyl tetrafluoride. Nature Chemistry |
| Brighty GJ, Botham RC, Li S, et al. (2020) Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery. Nature Chemistry |
| Smedley CJ, Li G, Barrow AS, et al. (2020) Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores From 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs. Angewandte Chemie (International Ed. in English) |
| Zheng Q, Woehl JL, Kitamura S, et al. (2019) SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proceedings of the National Academy of Sciences of the United States of America |
| Liu Z, Li J, Li S, et al. (2018) SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization. Journal of the American Chemical Society |
| Li GC, Wang P, Farmer ME, et al. (2017) Ligand-Enabled Auxiliary-Free Meta-C-H Arylation of Phenylacetic Acids. Angewandte Chemie (International Ed. in English) |
| Chen G, Zhuang Z, Li GC, et al. (2017) Ligand-Enabled β-C-H Arylation of α-Amino Acids Without Installing Exogenous Directing Groups. Angewandte Chemie (International Ed. in English) |
| Zhu RY, Tanaka K, Li GC, et al. (2015) Ligand-Enabled Stereoselective β-C(sp(3))-H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-amino Acids. Journal of the American Chemical Society. 137: 7067-70 |