William C. Hahn, M.D., Ph.D.
|Molecular and Cellular Oncology, Medical Oncology||Harvard Medical School, Dana Farber Cancer Institute, Broad Institute of Harvard and MIT,|
Area:EGFR , RNAi
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|Elmarakeby HA, Hwang J, Arafeh R, et al. (2021) Biologically informed deep neural network for prostate cancer discovery. Nature|
|Dai C, Rennhack JP, Arnoff TE, et al. (2021) SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization. Cell Reports. 36: 109443|
|Neggers JE, Paolella BR, Asfaw A, et al. (2021) Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q. Cell Reports. 36: 109367|
|Waters AM, Khatib TO, Papke B, et al. (2021) Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition. Cell Reports. 35: 109291|
|Cleary JM, Raghavan S, Wu Q, et al. (2021) FGFR2 Extracellular Domain In-Frame Deletions are Therapeutically Targetable Genomic Alterations that Function as Oncogenic Drivers in Cholangiocarcinoma. Cancer Discovery|
|Baca SC, Takeda DY, Seo JH, et al. (2021) Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer. Nature Communications. 12: 1979|
|Dharia NV, Kugener G, Guenther LM, et al. (2021) A first-generation pediatric cancer dependency map. Nature Genetics|
|Hahn WC, Bader JS, Braun TP, et al. (2021) An expanded universe of cancer targets. Cell. 184: 1142-1155|
|Way GP, Kost-Alimova M, Shibue T, et al. (2021) Predicting cell health phenotypes using image-based morphology profiling. Molecular Biology of the Cell. mbcE20120784|
|Kwon JJ, Hahn WC. (2021) A Leucine Rich Repeat Protein Provides a SHOC2 the RAS Circuit: A Structure-Function Perspective. Molecular and Cellular Biology|