G. Yancey Gillespie, Ph.D.

Immunology, Surgery University of Alabama, Birmingham, Birmingham, AL, United States 
cytosine deaminase, UPRT, PNP; HSV that include TNFa, IL-2, IL-4, IL-5, IL-10, IL12, IL-16
"G. Yancey Gillespie"



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Julius Major Cruse grad student 1971 University of Mississippi (Cell Biology Tree)
 (Mediation and suppression of the primary alloimmune response in vitro: a model for immunologic enhancement)


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C. Ryan Miller post-doc 2000-2002 UAB (Neurotree)
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Kim JH, Jeong K, Li J, et al. (2021) SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity. Nature Communications. 12: 5551
Kasten BB, Houson HA, Coleman JM, et al. (2021) Positron emission tomography imaging with Zr-labeled anti-CD8 cys-diabody reveals CD8 cell infiltration during oncolytic virus therapy in a glioma murine model. Scientific Reports. 11: 15384
Friedman GK, Johnston JM, Bag AK, et al. (2021) Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas. The New England Journal of Medicine
Osuka S, Zhu D, Zhang Z, et al. (2021) N-cadherin upregulation mediates adaptive radioresistance in glioblastoma. The Journal of Clinical Investigation. 131
Omar NB, Bentley RT, Crossman DK, et al. (2021) Safety and interim survival data after intracranial administration of M032, a genetically engineered oncolytic HSV-1 expressing IL-12, in pet dogs with sporadic gliomas. Neurosurgical Focus. 50: E5
Boyd NH, Tran AN, Bernstock JD, et al. (2021) Glioma stem cells and their roles within the hypoxic tumor microenvironment. Theranostics. 11: 665-683
Stackhouse CT, Gillespie GY, Willey CD. (2020) Exploring the Roles of lncRNAs in GBM Pathophysiology and Their Therapeutic Potential. Cells. 9
Eustace NJ, Anderson JC, Warram JM, et al. (2020) A cell-penetrating MARCKS mimetic selectively triggers cytolytic death in glioblastoma. Oncogene
Chambers MR, Bentley RT, Crossman DK, et al. (2020) The One Health Consortium: Design of a Phase I Clinical Trial to Evaluate M032, a Genetically Engineered HSV-1 Expressing IL-12, in Combination With a Checkpoint Inhibitor in Canine Patients With Sporadic High Grade Gliomas. Frontiers in Surgery. 7: 59
Kasten BB, Jiang K, Cole D, et al. (2019) Targeting MMP-14 for dual PET and fluorescence imaging of glioma in preclinical models. European Journal of Nuclear Medicine and Molecular Imaging
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