G. Yancey Gillespie, Ph.D.
|Immunology, Surgery||University of Alabama, Birmingham, Birmingham, AL, United States|
Area:cytosine deaminase, UPRT, PNP; HSV that include TNFa, IL-2, IL-4, IL-5, IL-10, IL12, IL-16
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|Kim JH, Jeong K, Li J, et al. (2021) SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity. Nature Communications. 12: 5551|
|Kasten BB, Houson HA, Coleman JM, et al. (2021) Positron emission tomography imaging with Zr-labeled anti-CD8 cys-diabody reveals CD8 cell infiltration during oncolytic virus therapy in a glioma murine model. Scientific Reports. 11: 15384|
|Friedman GK, Johnston JM, Bag AK, et al. (2021) Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas. The New England Journal of Medicine|
|Osuka S, Zhu D, Zhang Z, et al. (2021) N-cadherin upregulation mediates adaptive radioresistance in glioblastoma. The Journal of Clinical Investigation. 131|
|Omar NB, Bentley RT, Crossman DK, et al. (2021) Safety and interim survival data after intracranial administration of M032, a genetically engineered oncolytic HSV-1 expressing IL-12, in pet dogs with sporadic gliomas. Neurosurgical Focus. 50: E5|
|Boyd NH, Tran AN, Bernstock JD, et al. (2021) Glioma stem cells and their roles within the hypoxic tumor microenvironment. Theranostics. 11: 665-683|
|Stackhouse CT, Gillespie GY, Willey CD. (2020) Exploring the Roles of lncRNAs in GBM Pathophysiology and Their Therapeutic Potential. Cells. 9|
|Eustace NJ, Anderson JC, Warram JM, et al. (2020) A cell-penetrating MARCKS mimetic selectively triggers cytolytic death in glioblastoma. Oncogene|
|Chambers MR, Bentley RT, Crossman DK, et al. (2020) The One Health Consortium: Design of a Phase I Clinical Trial to Evaluate M032, a Genetically Engineered HSV-1 Expressing IL-12, in Combination With a Checkpoint Inhibitor in Canine Patients With Sporadic High Grade Gliomas. Frontiers in Surgery. 7: 59|
|Kasten BB, Jiang K, Cole D, et al. (2019) Targeting MMP-14 for dual PET and fluorescence imaging of glioma in preclinical models. European Journal of Nuclear Medicine and Molecular Imaging|