Joseph Costello, Ph.D.

Affiliations: 
Neurological Surgery University of California, San Francisco, San Francisco, CA 
Area:
Restriction Landmark Genomic Scanning (RLGS), CpG islands
Website:
http://neurosurgery.ucsf.edu/index.php/about_us_faculty_costello.html
Google:
"Joseph Costello"

Children

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Matt Ralph Grimmer grad student (Chemistry Tree)
Alika K. Maunakea grad student 2008 UCSF
Vanessa T. Angeles grad student 2009 UCSF
Stephen T. Magill post-doc UCSF (Neurotree)
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Publications

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Beccari S, Mohamed E, Voong V, et al. (2024) Quantitative assessment of preanalytic variables on clinical evaluation of PI3/AKT/mTOR signaling activity in diffuse glioma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 100488
Mathur R, Wang Q, Schupp PG, et al. (2024) Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective. Cell. 187: 446-463.e16
Appin CL, Hong C, Suwala AK, et al. (2023) Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression. Neuro-Oncology
Hadad S, Gupta R, Oberheim Bush NA, et al. (2023) "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade. Acta Neuropathologica. 147: 3
Schupp PG, Shelton SJ, Brody DJ, et al. (2023) Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections. Biorxiv : the Preprint Server For Biology
Williams EA, Ravindranathan A, Gupta R, et al. (2023) Novel SOX10 indel mutations drive schwannomas through impaired transactivation of myelination gene programs. Neuro-Oncology
Lucas CG, Sloan EA, Gupta R, et al. (2022) Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1. Acta Neuropathologica
Choudhury A, Magill ST, Eaton CD, et al. (2022) Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nature Genetics
Mohamed E, Kumar A, Zhang Y, et al. (2022) PI3K/AKT/mTOR signaling pathway activity in IDH-mutant diffuse glioma and clinical implications. Neuro-Oncology
Yu Y, Villanueva-Meyer J, Grimmer MR, et al. (2021) Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas. Neuro-Oncology
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