Paul Mischel, M.D.

Pathology University of California, San Diego, La Jolla, CA 
EGFR/PI3K/Akt/mTOR signaling network
"Paul Mischel"
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Harachi M, Masui K, Cavenee WK, et al. (2021) Protein Acetylation at the Interface of Genetics, Epigenetics and Environment in Cancer. Metabolites. 11
Wu S, Bafna V, Mischel PS. (2021) Extrachromosomal DNA (ecDNA) in cancer pathogenesis. Current Opinion in Genetics & Development. 66: 78-82
Wu S, Mischel PS. (2020) Same Script, Different Cast: Different Cell Origins Shape Molecular Features and Therapeutic Response in Glioblastoma. Cancer Cell. 38: 311-313
Luebeck J, Coruh C, Dehkordi SR, et al. (2020) AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications. Nature Communications. 11: 4374
Kim H, Nguyen NP, Turner K, et al. (2020) Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers. Nature Genetics
Chiu RWK, Dutta A, Hensson AG, et al. (2020) What Is Extrachromosomal Circular DNA and What Does It Do? Clinical Chemistry. 66: 754-759
Harachi M, Masui K, Honda H, et al. (2020) Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM. Molecular Cancer Research : McR
Koga T, Chaim IA, Benitez JA, et al. (2020) Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells. Nature Communications. 11: 1958
Bailey C, Shoura MJ, Mischel PS, et al. (2020) Extrachromosomal DNA - relieving heredity constraints, accelerating tumour evolution. Annals of Oncology : Official Journal of the European Society For Medical Oncology
Masui K, Harachi M, Cavenee WK, et al. (2020) mTOR complex 2 is an integrator of cancer metabolism and epigenetics. Cancer Letters
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