Dominique Broccoli - Publications

Affiliations: 
Laboratory Oncology Research Mercer University School of Medicine, Macon, GA, United States 

38/54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Greene A, Pascarelli K, Broccoli D, Perkins E. Engineering Synthetic Chromosomes by Sequential Loading of Multiple Genomic Payloads over 100 Kilobase Pairs in Size. Molecular Therapy. Methods & Clinical Development. 13: 463-473. PMID 31193384 DOI: 10.1016/J.Omtm.2019.04.006  0.398
2015 May CD, Garnett J, Ma X, Landers SM, Ingram DR, Demicco EG, Al Sannaa GA, Vu T, Han L, Zhang Y, Kivlin CM, Bolshakov S, Kalam AA, Liu J, Zhou F, ... Broccoli D, et al. AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas. Bmc Cancer. 15: 901. PMID 26573603 DOI: 10.1186/S12885-015-1916-3  0.367
2013 Plantinga MJ, Pascarelli KM, Merkel AS, Lazar AJ, von Mehren M, Lev D, Broccoli D. Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles. Molecular Cancer Research : McR. 11: 557-67. PMID 23505069 DOI: 10.1158/1541-7786.Mcr-13-0013  0.457
2012 Doyle KR, Mitchell MA, Roberts CL, James S, Johnson JE, Zhou Y, von Mehren M, Lev D, Kipling D, Broccoli D. Validating a gene expression signature proposed to differentiate liposarcomas that use different telomere maintenance mechanisms. Oncogene. 31: 265-6; author reply . PMID 21706060 DOI: 10.1038/Onc.2011.225  0.31
2011 Pascarelli K, Plantinga M, Doyle K, Roberts C, Zhou Y, Mehren Mv, Lev D, Broccoli D. Abstract 2019: An epigenetic reactivation screen identifies pathways important in pleomorphic liposarcomas Cancer Research. 71: 2019-2019. DOI: 10.1158/1538-7445.Am2011-2019  0.339
2010 Mitchell MA, Johnson JE, Pascarelli K, Beeharry N, Chiourea M, Gagos S, Lev D, von Mehren M, Kipling D, Broccoli D. Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres. Molecular Cancer Therapeutics. 9: 682-92. PMID 20197395 DOI: 10.1158/1535-7163.Mct-09-0705  0.393
2009 Caslini C, Connelly JA, Serna A, Broccoli D, Hess JL. MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Molecular and Cellular Biology. 29: 4519-26. PMID 19528237 DOI: 10.1128/Mcb.00195-09  0.496
2007 Deng Z, Dheekollu J, Broccoli D, Dutta A, Lieberman PM. The origin recognition complex localizes to telomere repeats and prevents telomere-circle formation. Current Biology : Cb. 17: 1989-95. PMID 18006317 DOI: 10.1016/J.Cub.2007.10.054  0.492
2007 Johnson JE, Gettings EJ, Schwalm J, Pei J, Testa JR, Litwin S, von Mehren M, Broccoli D. Whole-genome profiling in liposarcomas reveals genetic alterations common to specific telomere maintenance mechanisms. Cancer Research. 67: 9221-8. PMID 17909028 DOI: 10.1158/0008-5472.CAN-07-1133  0.336
2007 Johnson JE, Broccoli D. Telomere maintenance in sarcomas. Current Opinion in Oncology. 19: 377-82. PMID 17545803 DOI: 10.1097/Cco.0B013E3281214423  0.42
2005 von Mehren M, Varkonyi RJ, Johnson JE, Broccoli D. Mechanisms of telomere maintenance in liposarcomas (LPS). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 9017. PMID 27945548 DOI: 10.1200/Jco.2005.23.16_Suppl.9017  0.493
2005 Johnson JE, Varkonyi RJ, Schwalm J, Cragle R, Klein-Szanto A, Patchefsky A, Cukierman E, von Mehren M, Broccoli D. Multiple mechanisms of telomere maintenance exist in liposarcomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 5347-55. PMID 16061847 DOI: 10.1158/1078-0432.CCR-05-0684  0.462
2005 Beeharry N, Broccoli D. Telomere dynamics in response to chemotherapy. Current Molecular Medicine. 5: 187-96. PMID 15974872 DOI: 10.2174/1566524053586554  0.303
2004 Broccoli D. Function, replication and structure of the mammalian telomere. Cytotechnology. 45: 3-12. PMID 19003238 DOI: 10.1007/s10616-004-5120-6  0.44
2004 Xin Z, Broccoli D. Manipulating mouse telomeres: models of tumorigenesis and aging. Cytogenetic and Genome Research. 105: 471-8. PMID 15237236 DOI: 10.1159/000078221  0.468
2004 Razak ZR, Varkonyi RJ, Kulp-McEliece M, Caslini C, Testa JR, Murphy ME, Broccoli D. p53 differentially inhibits cell growth depending on the mechanism of telomere maintenance. Molecular and Cellular Biology. 24: 5967-77. PMID 15199150 DOI: 10.1128/MCB.24.13.5967-5977.2004  0.356
2004 Ibanez de Caceres I, Frolova N, Varkonyi RJ, Dulaimi E, Meropol NJ, Broccoli D, Cairns P. Telomerase is frequently activated in tumors with microsatellite instability. Cancer Biology & Therapy. 3: 289-92. PMID 14726659  0.335
2003 Deng Z, Atanasiu C, Burg JS, Broccoli D, Lieberman PM. Telomere repeat binding factors TRF1, TRF2, and hRAP1 modulate replication of Epstein-Barr virus OriP. Journal of Virology. 77: 11992-2001. PMID 14581536 DOI: 10.1128/Jvi.77.22.11992-12001.2003  0.359
2003 Armbruster BN, Etheridge KT, Broccoli D, Counter CM. Putative telomere-recruiting domain in the catalytic subunit of human telomerase. Molecular and Cellular Biology. 23: 3237-46. PMID 12697823 DOI: 10.1128/Mcb.23.9.3237-3246.2003  0.352
2001 Grobelny JV, Kulp-McEliece M, Broccoli D. Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway. Human Molecular Genetics. 10: 1953-61. PMID 11555632  0.398
2000 Grobelny JV, Godwin AK, Broccoli D. ALT-associated PML bodies are present in viable cells and are enriched in cells in the G(2)/M phase of the cell cycle. Journal of Cell Science. 113: 4577-85. PMID 11082050  0.361
1999 Kipling D, Wynford-Thomas D, Jones CJ, Akbar A, Aspinall R, Bacchetti S, Blasco MA, Broccoli D, DePinho RA, Edwards DR, Effros RB, Harley CB, Lansdorp PM, Linskens MH, Prowse KR, et al. Telomere-dependent senescence. Nature Biotechnology. 17: 313-4. PMID 10207859 DOI: 10.1038/7827  0.386
1999 Karlseder J, Broccoli D, Dai Y, Hardy S, de Lange T. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science (New York, N.Y.). 283: 1321-5. PMID 10037601 DOI: 10.1126/Science.283.5406.1321  0.63
1997 Broccoli D, Smogorzewska A, Chong L, de Lange T. Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. Nature Genetics. 17: 231-5. PMID 9326950 DOI: 10.1038/ng1097-231  0.659
1997 Broccoli D, Chong L, Oelmann S, Fernald AA, Marziliano N, van Steensel B, Kipling D, Le Beau MM, de Lange T. Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domains. Human Molecular Genetics. 6: 69-76. PMID 9002672 DOI: 10.1093/Hmg/6.1.69  0.609
1996 Broccoli D, Godley LA, Donehower LA, Varmus HE, de Lange T. Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation. Molecular and Cellular Biology. 16: 3765-72. PMID 8668193 DOI: 10.1128/Mcb.16.7.3765  0.602
1995 Garagna S, Broccoli D, Redi CA, Searle JB, Cooke HJ, Capanna E. Robertsonian metacentrics of the house mouse lose telomeric sequences but retain some minor satellite DNA in the pericentromeric area. Chromosoma. 103: 685-92. PMID 7664615 DOI: 10.1007/Bf00344229  0.412
1995 Broccoli D, Young JW, de Lange T. Telomerase activity in normal and malignant hematopoietic cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 9082-6. PMID 7568077 DOI: 10.1073/Pnas.92.20.9082  0.531
1995 Chong L, van Steensel B, Broccoli D, Erdjument-Bromage H, Hanish J, Tempst P, de Lange T. A human telomeric protein. Science (New York, N.Y.). 270: 1663-7. PMID 7502076 DOI: 10.1126/Science.270.5242.1663  0.658
1994 Broccoli D, Cooke HJ. Effect of telomeres on the interphase location of adjacent regions of the human X chromosome. Experimental Cell Research. 212: 308-13. PMID 8187823 DOI: 10.1006/excr.1994.1148  0.449
1994 Bayne RA, Broccoli D, Taggart MH, Thomson EJ, Farr CJ, Cooke HJ. Sandwiching of a gene within 12 kb of a functional telomere and alpha satellite does not result in silencing. Human Molecular Genetics. 3: 539-46. PMID 8069295 DOI: 10.1093/Hmg/3.4.539  0.467
1992 Broccoli D, Miller OJ, Miller DA. Isolation and characterization of a mouse subtelomeric sequence. Chromosoma. 101: 442-7. PMID 1618025 DOI: 10.1007/BF00582838  0.317
1991 Broccoli D, Trevor KT, Miller OJ, Miller DA. Isolation of a variant family of mouse minor satellite DNA that hybridizes preferentially to chromosome 4. Genomics. 10: 68-74. PMID 2045111 DOI: 10.1016/0888-7543(91)90485-W  0.31
1990 Broccoli D, Miller OJ, Miller DA. Relationship of mouse minor satellite DNA to centromere activity. Cytogenetics and Cell Genetics. 54: 182-6. PMID 2265565  0.402
1989 Broccoli D, Paweletz N, Vig BK. Sequence of centromere separation: characterization of multicentric chromosomes in a rat cell line. Chromosoma. 98: 13-22. PMID 2766876 DOI: 10.1007/BF00293330  0.36
1989 Vig BK, Paweletz N, Broccoli D. Centromere separation and aneuploidy: a lesson from multicentric chromosomes. Progress in Clinical and Biological Research. 318: 137-48. PMID 2696963  0.376
1988 Vig BK, Broccoli D. Sequence of centromere separation: differential replication of pericentric heterochromatin in multicentric chromosomes. Chromosoma. 96: 311-7. PMID 3383702 DOI: 10.1007/BF00286919  0.382
1986 Zinkowski RP, Vig BK, Broccoli D. Characterization of kinetochores in multicentric chromosomes. Chromosoma. 94: 243-8. PMID 3539553 DOI: 10.1007/BF00290851  0.375
Low-probability matches (unlikely to be authored by this person)
2008 McCord RA, Broccoli D. Telomeric chromatin: roles in aging, cancer and hereditary disease. Mutation Research. 647: 86-93. PMID 18778718 DOI: 10.1016/j.mrfmmm.2008.08.005  0.291
2004 Lareef MH, Tahin Q, Song J, Russo IH, Mihaila D, Slater CM, Balsara B, Testa JR, Broccoli D, Grobelny JV, Mor G, Cuthbert A, Russo J. Chromosome 17p13.2 transfer reverts transformation phenotypes and Fas-mediated apoptosis in breast epithelial cells. Molecular Carcinogenesis. 39: 234-46. PMID 15057875 DOI: 10.1002/mc.20014  0.281
2002 Foddis R, De Rienzo A, Broccoli D, Bocchetta M, Stekala E, Rizzo P, Tosolini A, Grobelny JV, Jhanwar SC, Pass HI, Testa JR, Carbone M. SV40 infection induces telomerase activity in human mesothelial cells. Oncogene. 21: 1434-42. PMID 11857086 DOI: 10.1038/Sj.Onc.1205203  0.265
2006 Chen X, Arciero CA, Wang C, Broccoli D, Godwin AK. BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation. Cancer Research. 66: 5039-46. PMID 16707425 DOI: 10.1158/0008-5472.CAN-05-4194  0.254
2002 Broccoli D, Godwin AK. Telomere length changes in human cancer. Methods in Molecular Medicine. 68: 271-8. PMID 11901508 DOI: 10.1385/1-59259-135-3:271  0.226
2011 Ghadimi MP, Liu P, Peng T, Bolshakov S, Young ED, Torres KE, Colombo C, Hoffman A, Broccoli D, Hornick JL, Lazar AJ, Pisters P, Pollock RE, Lev D. Pleomorphic liposarcoma: clinical observations and molecular variables. Cancer. 117: 5359-69. PMID 21598240 DOI: 10.1002/Cncr.26195  0.22
2021 Caslini C, Connelly JA, Serna A, Broccoli D, Hess JL. Erratum for Caslini et al., "MLL Associates with Telomeres and Regulates Telomeric Repeat-Containing RNA Transcription". Molecular and Cellular Biology. 41. PMID 33495397 DOI: 10.1128/MCB.00566-20  0.21
2004 Lewis NL, Mullaney M, Mangan KF, Klumpp T, Rogatko A, Broccoli D. Measurable immune dysfunction and telomere attrition in long-term allogeneic transplant recipients. Bone Marrow Transplantation. 33: 71-8. PMID 14704659 DOI: 10.1038/sj.bmt.1704300  0.204
2014 Shaker M, Pascarelli KM, Plantinga MJ, Love MA, Lazar AJ, Ingram DR, von Mehren M, Lev D, Kipling D, Broccoli D. Differential expression of cysteine dioxygenase 1 in complex karyotype liposarcomas. Biomarkers in Cancer. 6: 1-10. PMID 24741338 DOI: 10.4137/BIC.S14683  0.201
2001 Grant JD, Broccoli D, Muquit M, Manion FJ, Tisdall J, Ochs MF. Telometric: a tool providing simplified, reproducible measurements of telomeric DNA from constant field agarose gels. Biotechniques. 31: 1314-6, 1318. PMID 11768660  0.2
2003 Brown T, Sigurdson E, Rogatko A, Broccoli D. Telomerase inhibition using azidothymidine in the HT-29 colon cancer cell line. Annals of Surgical Oncology. 10: 910-5. PMID 14527910 DOI: 10.1245/ASO.2003.03.032  0.153
1993 Broccoli D, Cooke H. Aging, healing, and the metabolism of telomeres. American Journal of Human Genetics. 52: 657-60. PMID 8460631  0.108
2015 Hines RB, Barrett A, Twumasi-Ankrah P, Broccoli D, Engelman KK, Baranda J, Ablah EA, Jacobson L, Redmond M, Tu W, Collins TC. Predictors of guideline treatment nonadherence and the impact on survival in patients with colorectal cancer. Journal of the National Comprehensive Cancer Network : Jnccn. 13: 51-60. PMID 25583769 DOI: 10.1200/Jco.2014.32.30_Suppl.254  0.038
2014 Barrett A, Twumasi-Ankrah P, Broccoli D, Engelman KK, Baranda JC, Ablah E, Jacobson L, Redmond M, Tu W, Collins T. Predictors of guideline treatment nonadherence and the impact on survival in patients with colorectal cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 254. PMID 28141314 DOI: 10.1200/jco.2014.32.30_suppl.254  0.037
2006 Bagli S, Mazzoli P, Pistocchi A, Broccoli D. Integrated design International Water Power and Dam Construction. 58: 34-35.  0.026
2014 Pawasauskas J, Broccoli D. (422) Pain-related characteristics of inpatient admissions for acute pancreatitis: a retrospective study The Journal of Pain. 15: S81. DOI: 10.1016/j.jpain.2014.01.333  0.01
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