Omer H. Yilmaz, Ph.D. - Publications

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Stem cells

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Schmidt DR, Gramatikov IMT, Sheen A, Williams CL, Hurwitz M, Dodge LE, Holupka E, Kiger WS, Cornwall-Brady MR, Huang W, Mak HH, Cormier KS, Condon C, Dane Wittrup K, Yilmaz ÖH, et al. Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer. Communications Medicine. 3: 108. PMID 37558833 DOI: 10.1038/s43856-023-00336-3  0.581
2023 He S, Lei P, Kang W, Cheung P, Xu T, Mana M, Park CY, Wang H, Imada S, Russell JO, Wang J, Wang R, Zhou Z, Chetal K, Stas E, et al. Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Towards Goblet Cells. Gastroenterology. PMID 36871599 DOI: 10.1053/j.gastro.2023.02.030  0.32
2022 Sedlak JC, Yilmaz ÖH, Roper J. Metabolism and Colorectal Cancer. Annual Review of Pathology. PMID 36323004 DOI: 10.1146/annurev-pathmechdis-031521-041113  0.651
2022 Mead BE, Hattori K, Levy L, Imada S, Goto N, Vukovic M, Sze D, Kummerlowe C, Matute JD, Duan J, Langer R, Blumberg RS, Ordovas-Montanes J, Yilmaz ÖH, Karp JM, et al. Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation. Nature Biomedical Engineering. PMID 35314801 DOI: 10.1038/s41551-022-00863-9  0.34
2021 Wu X, Ueland PM, Roper J, Koh GY, Liang X, Crott JW, Yilmaz ÖH, Bronson RT, Mason JB. Combined Supplementation with Vitamin B-6 and Curcumin is Superior to Either Agent Alone in Suppressing Obesity-Promoted Colorectal Tumorigenesis in Mice. The Journal of Nutrition. PMID 34590119 DOI: 10.1093/jn/nxab320  0.586
2021 Beyaz S, Chung C, Mou H, Bauer-Rowe KE, Xifaras ME, Ergin I, Dohnalova L, Biton M, Shekhar K, Eskiocak O, Papciak K, Ozler K, Almeqdadi M, Yueh B, Fein M, et al. Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis. Cell Stem Cell. PMID 34529935 DOI: 10.1016/j.stem.2021.08.007  0.739
2021 Shin JH, Jeong J, Choi J, Lim J, Dinesh RK, Braverman J, Hong JY, Maher SE, Amezcua Vesely MC, Kim W, Koo JH, Tang W, Wu D, Blackburn HN, Xicola RM, ... ... Yilmaz O, et al. Dickkopf-2 regulates the stem cell marker LGR5 in colorectal cancer via HNF4α1. Iscience. 24: 102411. PMID 33997693 DOI: 10.1016/j.isci.2021.102411  0.361
2021 Beyaz S, Mana MD, Yilmaz ÖH. High-fat diet activates a PPAR-δ program to enhance intestinal stem cell function. Cell Stem Cell. 28: 598-599. PMID 33798420 DOI: 10.1016/j.stem.2021.03.001  0.719
2020 Kong YW, Dreaden EC, Morandell S, Zhou W, Dhara SS, Sriram G, Lam FC, Patterson JC, Quadir M, Dinh A, Shopsowitz KE, Varmeh S, Yilmaz ÖH, Lippard SJ, Reinhardt HC, et al. Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints. Nature Communications. 11: 4124. PMID 32807787 DOI: 10.1038/S41467-020-17958-Z  0.302
2020 Cheung P, Xiol J, Dill MT, Yuan WC, Panero R, Roper J, Osorio FG, Maglic D, Li Q, Gurung B, Calogero RA, Yilmaz ÖH, Mao J, Camargo FD. Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer. Cell Stem Cell. PMID 32730753 DOI: 10.1016/J.Stem.2020.07.003  0.71
2020 Cheng CW, Yilmaz OH, Mihaylova MM. Strategies for Measuring Induction of Fatty Acid Oxidation in Intestinal Stem and Progenitor Cells. Methods in Molecular Biology (Clifton, N.J.). 2171: 53-64. PMID 32705635 DOI: 10.1007/978-1-0716-0747-3_4  0.354
2020 Lau AN, Li Z, Danai LV, Westermark AM, Darnell AM, Ferreira R, Gocheva V, Sivanand S, Lien EC, Sapp KM, Mayers JR, Biffi G, Chin CR, Davidson SM, Tuveson DA, ... ... Yilmaz O, et al. Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma. Elife. 9. PMID 32648540 DOI: 10.7554/Elife.56782  0.405
2020 Gebert N, Cheng CW, Kirkpatrick JM, Di Fraia D, Yun J, Schädel P, Pace S, Garside GB, Werz O, Rudolph KL, Jasper H, Yilmaz ÖH, Ori A. Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction. Cell Reports. 31: 107565. PMID 32348758 DOI: 10.1016/J.Celrep.2020.107565  0.392
2020 Trapecar M, Communal C, Velazquez J, Maass CA, Huang YJ, Schneider K, Wright CW, Butty V, Eng G, Yilmaz O, Trumper D, Griffith LG. Gut-Liver Physiomimetics Reveal Paradoxical Modulation of IBD-Related Inflammation by Short-Chain Fatty Acids. Cell Systems. PMID 32191873 DOI: 10.1016/J.Cels.2020.02.008  0.347
2020 Lau AN, Li Z, Danai LV, Westermark AM, Darnell AM, Ferreira R, Gocheva V, Sivanand S, Lien EC, Sapp KM, Mayers JR, Biffi G, Chin CR, Davidson SM, Tuveson DA, ... ... Yilmaz O, et al. Author response: Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma Elife. DOI: 10.7554/Elife.56782.Sa2  0.3
2019 Hynes RO, Rickelt S, Condon C, Mana M, Whittaker C, Pfirschke C, Roper J, Patil DT, Brown I, Mattia AR, Zukerberg L, Zhao Q, Chetty R, Lauwers GY, Neyaz A, ... ... Yilmaz OH, et al. Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31852835 DOI: 10.1158/1078-0432.Ccr-19-2898  0.606
2019 Jackstadt R, van Hooff SR, Leach JD, Cortes-Lavaud X, Lohuis JO, Ridgway RA, Wouters VM, Roper J, Kendall TJ, Roxburgh CS, Horgan PG, Nixon C, Nourse C, Gunzer M, Clark W, ... ... Yilmaz OH, et al. Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis. Cancer Cell. 36: 319-336.e7. PMID 31526760 DOI: 10.1016/J.Ccell.2019.08.003  0.652
2019 Dittmann A, Kennedy NJ, Soltero NL, Morshed N, Mana MD, Yilmaz ÖH, Davis RJ, White FM. High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network. Molecular Systems Biology. 15: e8849. PMID 31464373 DOI: 10.15252/Msb.20198849  0.31
2019 Cheng CW, Biton M, Haber AL, Gunduz N, Eng G, Gaynor LT, Tripathi S, Calibasi-Kocal G, Rickelt S, Butty VL, Moreno-Serrano M, Iqbal AM, Bauer-Rowe KE, Imada S, Ulutas MS, et al. Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. Cell. 178: 1115-1131.e15. PMID 31442404 DOI: 10.1016/J.Cell.2019.07.048  0.433
2019 Venkateswaran N, Lafita-Navarro MC, Hao YH, Kilgore JA, Perez-Castro L, Braverman J, Borenstein-Auerbach N, Kim M, Lesner NP, Mishra P, Brabletz T, Shay JW, DeBerardinis RJ, Williams NS, Yilmaz OH, et al. MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer. Genes & Development. PMID 31416966 DOI: 10.1101/Gad.327056.119  0.403
2019 Pentinmikko N, Iqbal S, Mana M, Andersson S, Cognetta AB, Suciu RM, Roper J, Luopajärvi K, Markelin E, Gopalakrishnan S, Smolander OP, Naranjo S, Saarinen T, Juuti A, Pietiläinen K, et al. Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium. Nature. PMID 31292548 DOI: 10.1038/S41586-019-1383-0  0.743
2019 Almeqdadi M, Mana MD, Roper J, Yilmaz ÖH. Gut Organoids: Mini-Tissues in Culture to Study Intestinal Physiology and Disease. American Journal of Physiology. Cell Physiology. PMID 31216420 DOI: 10.1152/Ajpcell.00300.2017  0.666
2019 Roper J, Yilmaz ÖH. Breakthrough Moments: Genome Editing and Organoids. Cell Stem Cell. 24: 841-842. PMID 31173713 DOI: 10.1016/J.Stem.2019.05.008  0.59
2019 Peng B, Almeqdadi M, Laroche F, Palantavida S, Dokukin M, Roper J, Yilmaz OH, Feng H, Sokolov I. Ultrabright fluorescent cellulose acetate nanoparticles for imaging tumors through systemic and topical applications. Materials Today (Kidlington, England). 23: 16-25. PMID 31057328 DOI: 10.1016/J.Mattod.2018.11.001  0.595
2019 Peng B, Almeqdadi M, Laroche F, Palantavida S, Dokukin M, Roper J, Yilmaz OH, Feng H, Sokolov I. Data on ultrabright fluorescent cellulose acetate nanoparticles for imaging tumors through systemic and topical applications. Data in Brief. 22: 383-391. PMID 30596135 DOI: 10.1016/J.Dib.2018.12.030  0.583
2019 Freed-Pastor WA, Lambert L, Garcia AP, Eng G, Yilmaz O, Jacks T. Abstract PR14: Preclinical models to dissect immune escape in pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-Pr14  0.377
2019 Schmidt DR, Roper J, Santos S, Yilmaz OH, Heiden MGV. 453 – Therapeutic Dose of Pelvic Radiation Slows Tumor Growth and Improves Survival in a Genetically Engineered Mouse Model of Colorectal Cancer Gastroenterology. 156: S-95. DOI: 10.1016/S0016-5085(19)37026-X  0.619
2018 Song M, Wu K, Meyerhardt JA, Yilmaz O, Wang M, Ogino S, Fuchs CS, Giovannucci EL, Chan AT. Low-Carbohydrate Diet Score and Macronutrient Intake in Relation to Survival After Colorectal Cancer Diagnosis. Jnci Cancer Spectrum. 2: pky077. PMID 30734025 DOI: 10.1093/Jncics/Pky077  0.31
2018 Biton M, Haber AL, Rogel N, Burgin G, Beyaz S, Schnell A, Ashenberg O, Su CW, Smillie C, Shekhar K, Chen Z, Wu C, Ordovas-Montanes J, Alvarez D, Herbst RH, ... ... Yilmaz OH, et al. T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation. Cell. PMID 30392957 DOI: 10.1016/J.Cell.2018.10.008  0.753
2018 Eng G, Braverman J, Yilmaz ÖH. CRAD as a cytoskeletal tumour suppressor. Nature Cell Biology. 20: 1232-1233. PMID 30361696 DOI: 10.1038/S41556-018-0225-X  0.339
2018 Yilmaz ÖH. Dietary regulation of the origins of cancer. Science Translational Medicine. 10. PMID 30089636 DOI: 10.1126/Scitranslmed.Aat8285  0.459
2018 Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, et al. Author Correction: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature. PMID 29849139 DOI: 10.1038/S41586-018-0187-Y  0.734
2018 Alonso S, Yilmaz ÖH. Nutritional Regulation of Intestinal Stem Cells. Annual Review of Nutrition. PMID 29799767 DOI: 10.1146/Annurev-Nutr-082117-051644  0.406
2018 Mihaylova MM, Cheng CW, Cao AQ, Tripathi S, Mana MD, Bauer-Rowe KE, Abu-Remaileh M, Clavain L, Erdemir A, Lewis CA, Freinkman E, Dickey AS, La Spada AR, Huang Y, Bell GW, et al. Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging. Cell Stem Cell. 22: 769-778.e4. PMID 29727683 DOI: 10.1016/J.Stem.2018.04.001  0.767
2018 Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, et al. Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis. Gut. PMID 29666172 DOI: 10.1136/Gutjnl-2017-315920  0.63
2018 Zhou W, Almeqdadi M, Xifaras ME, Riddell IA, Yilmaz ÖH, Lippard SJ. The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex trans-[Pt(NH)(phenanthridine)Cl]NO. Chemical Communications (Cambridge, England). PMID 29484327 DOI: 10.1039/C8Cc00393A  0.307
2018 Cheng CW, Yilmaz ÖH. FAOund the Link: Phospholipid Remodeling and Intestinal Stem Cell Growth and Tumorigenesis. Cell Stem Cell. 22: 141-143. PMID 29395049 DOI: 10.1016/J.Stem.2018.01.009  0.432
2018 Roper J, Tammela T, Akkad A, Almeqdadi M, Santos SB, Jacks T, Yilmaz ÖH. Colonoscopy-based colorectal cancer modeling in mice with CRISPR-Cas9 genome editing and organoid transplantation. Nature Protocols. 13: 217-234. PMID 29300388 DOI: 10.1038/Nprot.2017.136  0.664
2018 Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli M, Sánchez-Rivera F, Park Y, Liang X, Eng G, Taylor MS, Azimi R, et al. Abstract B38: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-B38  0.798
2017 Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, et al. Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nature Biotechnology. 35: 1211. PMID 29220013 DOI: 10.1038/Nbt1217-1211A  0.77
2017 Lau AN, Israelsen WJ, Roper J, Sinnamon MJ, Georgeon L, Dayton TL, Hillis AL, Yilmaz OH, Di Vizio D, Hung KE, Vander Heiden MG. PKM2 is not required for colon cancer initiated by APC loss. Cancer & Metabolism. 5: 10. PMID 29214019 DOI: 10.1186/S40170-017-0172-1  0.656
2017 Haber AL, Biton M, Rogel N, Herbst RH, Shekhar K, Smillie C, Burgin G, Delorey TM, Howitt MR, Katz Y, Tirosh I, Beyaz S, Dionne D, Zhang M, Raychowdhury R, ... ... Yilmaz O, et al. A single-cell survey of the small intestinal epithelium. Nature. 551: 333-339. PMID 29144463 DOI: 10.1038/Nature24489  0.741
2017 Mana MD, Kuo EY, Yilmaz ÖH. Dietary Regulation of Adult Stem Cells. Current Stem Cell Reports. 3: 1-8. PMID 28966904 DOI: 10.1007/S40778-017-0072-X  0.429
2017 Tammela T, Sanchez-Rivera FJ, Cetinbas NM, Wu K, Joshi NS, Helenius K, Park Y, Azimi R, Kerper NR, Wesselhoeft RA, Gu X, Schmidt L, Cornwall-Brady M, Yilmaz ÖH, Xue W, et al. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature. PMID 28489818 DOI: 10.1038/Nature22334  0.44
2017 Roper J, Yilmaz ÖH. Metabolic Teamwork in the Stem Cell Niche. Cell Metabolism. 25: 993-994. PMID 28467944 DOI: 10.1016/J.Cmet.2017.04.019  0.688
2017 Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, et al. In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nature Biotechnology. PMID 28459449 DOI: 10.1038/Nbt.3836  0.801
2017 Barriga FM, Montagni E, Mana M, Mendez-Lago M, Hernando-Momblona X, Sevillano M, Guillaumet-Adkins A, Rodriguez-Esteban G, Buczacki SJ, Gut M, Heyn H, Winton DJ, Yilmaz OH, Attolini CS, Gut I, et al. Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells. Cell Stem Cell. PMID 28285904 DOI: 10.1016/J.Stem.2017.02.007  0.432
2017 Cheng CW, Villani V, Buono R, Wei M, Kumar S, Yilmaz OH, Cohen P, Sneddon JB, Perin L, Longo VD. Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes. Cell. 168: 775-788.e12. PMID 28235195 DOI: 10.1016/J.Cell.2017.01.040  0.331
2017 Kedrin D, Gandhi SC, Wolf M, Roper J, Yilmaz O, Corey K, Khalili H, Stanford FC, Gala M. Bariatric Surgery Prior to Index Screening Colonoscopy Is Associated With a Decreased Rate of Colorectal Adenomas in Obese Individuals. Clinical and Translational Gastroenterology. 8: e73. PMID 28181993 DOI: 10.1038/Ctg.2017.1  0.598
2017 Cheng CW, Yilmaz ÖH. Starving leukemia to induce differentiation. Nature Medicine. 23: 14-15. PMID 28060803 DOI: 10.1038/Nm.4259  0.301
2017 Beytagh MC, Westcott PM, Smith OC, Roper J, Yilmaz O, Jacks TE. Abstract 5018: Dissecting antigen-specific T-cell response in a novel mouse model of colon cancer Cancer Research. 77: 5018-5018. DOI: 10.1158/1538-7445.Am2017-5018  0.649
2017 Song M, Wu K, Meyerhardt J, Yilmaz O, Ogino S, Fuchs C, Giovannucci E, Chan AT. Abstract 3270: Association of low-carbohydrate diet and macronutrient intake with colorectal cancer survival Cancer Research. 77: 3270-3270. DOI: 10.1158/1538-7445.Am2017-3270  0.33
2016 Beyaz S, Kim JH, Pinello L, Xifaras ME, Hu Y, Huang J, Kerenyi MA, Das PP, Barnitz RA, Herault A, Dogum R, Haining WN, Yilmaz ÖH, Passegue E, Yuan GC, et al. The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells. Nature Immunology. PMID 27992400 DOI: 10.1038/Ni.3644  0.756
2016 Yilmaz OH, Beyaz S. Molecular Pathways: Dietary regulation of stemness and tumor initiation by the PPAR-δ pathway. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27702819 DOI: 10.1158/1078-0432.Ccr-16-0775  0.757
2016 Cetinbas NM, Sudderth J, Harris RC, Cebeci A, Negri GL, Yılmaz ÖH, DeBerardinis RJ, Sorensen PH. Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine. Scientific Reports. 6: 32606. PMID 27605385 DOI: 10.1038/Srep32606  0.365
2016 Dominguez-Brauer C, Hao Z, Elia AJ, Fortin JM, Nechanitzky R, Brauer PM, Sheng Y, Mana MD, Chio II, Haight J, Pollett A, Cairns R, Tworzyanski L, Inoue S, Reardon C, ... ... Yilmaz OH, et al. Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation. Cell Stem Cell. PMID 27184401 DOI: 10.1016/J.Stem.2016.04.002  0.63
2016 Cangelosi AL, Yilmaz ÖH. High fat diet and stem cells: Linking diet to intestinal tumor formation. Cell Cycle (Georgetown, Tex.). 1-2. PMID 27097128 DOI: 10.1080/15384101.2016.1175275  0.395
2016 Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, et al. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature. 531: 53-8. PMID 26935695 DOI: 10.1038/Nature17173  0.785
2016 Roper J, Tammela T, Cetinbas N, Sanchez-Rivera F, Almeqdadi M, Azimy R, Park Y, Kedrin D, Akkad A, Bauer-Rowe K, Neupane R, Yilmaz OH. 30 Sequential Genome Editing in CRISPR/Cas9-Based Colorectal Cancer Mouse Models Gastroenterology. 150: S10-S11. DOI: 10.1016/S0016-5085(16)30165-2  0.627
2015 Cheng CW, Yilmaz ÖH. IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy. Cell Stem Cell. 17: 379-80. PMID 26431180 DOI: 10.1016/J.Stem.2015.09.008  0.398
2015 Golovko D, Kedrin D, Yilmaz ÖH, Roper J. Colorectal cancer models for novel drug discovery. Expert Opinion On Drug Discovery. 1-13. PMID 26295972 DOI: 10.1517/17460441.2015.1079618  0.648
2014 Lamming DW, Mihaylova MM, Katajisto P, Baar EL, Yilmaz OH, Hutchins A, Gultekin Y, Gaither R, Sabatini DM. Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan. Aging Cell. 13: 911-7. PMID 25059582 DOI: 10.1111/Acel.12256  0.661
2014 Lassen KG, Kuballa P, Conway KL, Patel KK, Becker CE, Peloquin JM, Villablanca EJ, Norman JM, Liu TC, Heath RJ, Becker ML, Fagbami L, Horn H, Mercer J, Yilmaz OH, et al. Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense. Proceedings of the National Academy of Sciences of the United States of America. 111: 7741-6. PMID 24821797 DOI: 10.1073/Pnas.1407001111  0.309
2014 Mihaylova MM, Sabatini DM, Yilmaz ÖH. Dietary and metabolic control of stem cell function in physiology and cancer. Cell Stem Cell. 14: 292-305. PMID 24607404 DOI: 10.1016/J.Stem.2014.02.008  0.626
2014 Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray MA, Gopal S, Theisen MA, Bilodeau S, Thiru P, Muffat J, Yilmaz OH, Mitalipova M, Woolard K, Lee J, et al. ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state. Cell Reports. 6: 313-24. PMID 24440720 DOI: 10.1016/J.Celrep.2013.12.032  0.671
2013 Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, et al. Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection. Gastroenterology. 145: 1347-57. PMID 23973919 DOI: 10.1053/J.Gastro.2013.08.035  0.317
2013 Arnason T, Pino MS, Yilmaz O, Kirley SD, Rueda BR, Chung DC, Zukerberg LR. Cables1 is a tumor suppressor gene that regulates intestinal tumor progression in Apc(Min) mice. Cancer Biology & Therapy. 14: 672-8. PMID 23792637 DOI: 10.4161/Cbt.25089  0.383
2013 Curry NL, Mino-Kenudson M, Oliver TG, Yilmaz OH, Yilmaz VO, Moon JY, Jacks T, Sabatini DM, Kalaany NY. Pten-null tumors cohabiting the same lung display differential AKT activation and sensitivity to dietary restriction. Cancer Discovery. 3: 908-21. PMID 23719831 DOI: 10.1158/2159-8290.Cd-12-0507  0.55
2013 Birsoy K, Wang T, Possemato R, Yilmaz OH, Koch CE, Chen WW, Hutchins AW, Gultekin Y, Peterson TR, Carette JE, Brummelkamp TR, Clish CB, Sabatini DM. MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors. Nature Genetics. 45: 104-8. PMID 23202129 DOI: 10.1038/Ng.2471  0.726
2013 Curry NL, Mino-Kenudson M, Oliver TG, Yilmaz OH, Yilmaz VO, Moon J, Jacks T, Sabatini DM, Kalaany NY. Abstract 4317: PTEN-null tumors cohabiting the same lung display differential Akt activation and sensitivity to dietary restriction. Cancer Research. 73: 4317-4317. DOI: 10.1158/1538-7445.Am2013-4317  0.562
2010 Lee JY, Nakada D, Yilmaz OH, Tothova Z, Joseph NM, Lim MS, Gilliland DG, Morrison SJ. mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion. Cell Stem Cell. 7: 593-605. PMID 21040901 DOI: 10.1016/J.Stem.2010.09.015  0.789
2009 Oravecz-Wilson KI, Philips ST, Yilmaz OH, Ames HM, Li L, Crawford BD, Gauvin AM, Lucas PC, Sitwala K, Downing JR, Morrison SJ, Ross TS. Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder. Cancer Cell. 16: 137-48. PMID 19647224 DOI: 10.1016/J.Ccr.2009.06.007  0.51
2009 Levi BP, Yilmaz OH, Duester G, Morrison SJ. Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood. 113: 1670-80. PMID 18971422 DOI: 10.1182/Blood-2008-05-156752  0.776
2008 Kiel MJ, Yilmaz OH, Morrison SJ. CD150- cells are transiently reconstituting multipotent progenitors with little or no stem cell activity. Blood. 111: 4413-4; author reply. PMID 18398056 DOI: 10.1182/Blood-2007-12-129601  0.758
2008 Yilmaz OH, Morrison SJ. The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells. Blood Cells, Molecules & Diseases. 41: 73-6. PMID 18387833 DOI: 10.1016/J.Bcmd.2008.02.004  0.62
2006 Yilmaz OH, Valdez R, Theisen BK, Guo W, Ferguson DO, Wu H, Morrison SJ. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature. 441: 475-82. PMID 16598206 DOI: 10.1038/Nature04703  0.627
2006 Kim I, He S, Yilmaz OH, Kiel MJ, Morrison SJ. Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. Blood. 108: 737-44. PMID 16569764 DOI: 10.1182/Blood-2005-10-4135  0.761
2006 Yilmaz OH, Kiel MJ, Morrison SJ. SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood. 107: 924-30. PMID 16219798 DOI: 10.1182/Blood-2005-05-2140  0.761
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2005 Kiel MJ, Iwashita T, Yilmaz OH, Morrison SJ. Spatial differences in hematopoiesis but not in stem cells indicate a lack of regional patterning in definitive hematopoietic stem cells. Developmental Biology. 283: 29-39. PMID 15913595 DOI: 10.1016/J.Ydbio.2005.03.037  0.792
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