| Year |
Citation |
Score |
| 2024 |
Varney MJ, Benovic JL. The Role of G Protein-Coupled Receptors and Receptor Kinases in Pancreatic -Cell Function and Diabetes. Pharmacological Reviews. 76: 267-299. PMID 38351071 DOI: 10.1124/pharmrev.123.001015 |
0.371 |
|
| 2023 |
Lefkowitz RJ, Rockman HA, Shim PJ, Liu S, Ahn S, Pani B, Rajagopal S, Shenoy SK, Bouvier M, Benovic JL, Liggett SB, Ruffolo RR, Bristow MR, Packer M. How carvedilol does not activate β-adrenoceptors. Nature Communications. 14: 7866. PMID 38036531 DOI: 10.1038/s41467-023-42848-5 |
0.756 |
|
| 2023 |
Ippolito M, De Pascali F, Hopfinger N, Komolov KE, Laurinavichyute D, Reddy PAN, Sakkal LA, Rajkowski KZ, Nayak AP, Lee J, Lee J, Cao G, Donover PS, Reichman M, An SS, ... ... Benovic JL, et al. Identification of a β-arrestin-biased negative allosteric modulator for the β-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302668120. PMID 37490535 DOI: 10.1073/pnas.2302668120 |
0.365 |
|
| 2022 |
De Pascali F, Ippolito M, Wolfe E, Komolov KE, Hopfinger N, Lemenze D, Kim N, Armen RS, An SS, Scott CP, Benovic JL. β-agonist profiling reveals biased signalling phenotypes for the β -adrenergic receptor with possible implications for the treatment of asthma. British Journal of Pharmacology. PMID 35732075 DOI: 10.1111/bph.15900 |
0.328 |
|
| 2022 |
Okyere AD, Song J, Patwa V, Carter RL, Enjamuri N, Lucchese AM, Ibetti J, de Lucia C, Schumacher SM, Koch WJ, Cheung JY, Benovic JL, Tilley DG. Pepducin ICL1-9-Mediated β2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a G Protein/ROCK/PKD-Sensitive Manner. Cardiovascular Drugs and Therapy. PMID 34997361 DOI: 10.1007/s10557-021-07299-4 |
0.553 |
|
| 2021 |
Ippolito M, De Pascali F, Inoue A, Benovic JL. Phenylalanine 193 in Extracellular Loop 2 of the -Adrenergic Receptor Coordinates -Arrestin Interaction. Molecular Pharmacology. 101: 87-94. PMID 34853152 DOI: 10.1124/molpharm.121.000332 |
0.464 |
|
| 2021 |
Benovic JL. Historical Perspective of the G Protein-Coupled Receptor Kinase Family. Cells. 10. PMID 33806476 DOI: 10.3390/cells10030555 |
0.486 |
|
| 2021 |
Sulon SM, Benovic JL. Targeting G protein-coupled receptor kinases (GRKs) to G protein-coupled receptors. Current Opinion in Endocrine and Metabolic Research. 16: 56-65. PMID 33718657 DOI: 10.1016/J.Coemr.2020.09.002 |
0.56 |
|
| 2020 |
Ippolito M, Benovic JL. Biased agonism at β-adrenergic receptors. Cellular Signalling. 80: 109905. PMID 33385503 DOI: 10.1016/j.cellsig.2020.109905 |
0.301 |
|
| 2020 |
Komolov KE, Sulon SM, Bhardwaj A, van Keulen SC, Duc NM, Laurinavichyute DK, Lou HJ, Turk BE, Chung KY, Dror RO, Benovic JL. Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting. Molecular Cell. PMID 33321095 DOI: 10.1016/j.molcel.2020.11.026 |
0.378 |
|
| 2020 |
Yoo SM, Bhardwaj A, Benovic JL. Arresting Developments in Biased Signaling. Trends in Pharmacological Sciences. PMID 32362341 DOI: 10.1016/J.Tips.2020.04.003 |
0.425 |
|
| 2020 |
Chen X, Gupta S, Cooper M, DeHelian D, Zhao X, Naik MU, Wurtzel JGT, Stalker TJ, Goldfinger LE, Benovic J, Brass LF, McKenzie SE, Naik UP, Ma P. GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets. Blood Advances. 4: 76-86. PMID 31899801 DOI: 10.1182/Blood-2019-129175 |
0.36 |
|
| 2019 |
Lagman J, Sayegh P, Lee CS, Sulon SM, Jacinto AZ, Sok V, Peng N, Alp D, Benovic JL, So CH. G protein-coupled receptor kinase 5 modifies cancer cell resistance to paclitaxel. Molecular and Cellular Biochemistry. PMID 31363957 DOI: 10.1007/S11010-019-03594-9 |
0.51 |
|
| 2019 |
Okyere AD, de Lucia C, Song J, Carter RL, Benovic JL, Koch WJ, Cheung JY, Tilley DG. Abstract 757: β-arrestin-Biased β2-Adrenergic Receptor Signaling Mediates Novel Mechanisms of Cardiomyocyte Contractility Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.757 |
0.565 |
|
| 2018 |
Grisanti LA, Thomas TP, Carter RL, de Lucia C, Gao E, Koch WJ, Benovic JL, Tilley DG. Pepducin-mediated cardioprotection via β-arrestin-biased β2-adrenergic receptor-specific signaling. Theranostics. 8: 4664-4678. PMID 30279730 DOI: 10.7150/Thno.26619 |
0.482 |
|
| 2018 |
Chaturvedi M, Schilling J, Beautrait A, Bouvier M, Benovic JL, Shukla AK. Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors. Trends in Biochemical Sciences. PMID 29735399 DOI: 10.1016/J.Tibs.2018.04.003 |
0.675 |
|
| 2018 |
Panettieri RA, Pera T, Liggett SB, Benovic JL, Penn RB. Pepducins as a potential treatment strategy for asthma and COPD. Current Opinion in Pharmacology. 40: 120-125. PMID 29729548 DOI: 10.1016/J.Coph.2018.04.008 |
0.57 |
|
| 2018 |
Grisanti LA, Thomas TP, de Lucia C, Carter RL, Gao E, Koch WJ, Benovic JL, Tilley DG. Abstract 580: A β-arrestin-Biased β2-Adrenergic Receptor-Specific Pepducin Confers Cardioprotection Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.580 |
0.552 |
|
| 2018 |
Okyere AD, de Lucia C, Song J, Carter RL, Benovic JL, Koch WJ, Cheung JY, Tilley DG. Abstract 578: β-arrestin-Biased β2-Adrenergic Receptor Signaling Enhances Cardiomyocyte Contractility via ROCK-Dependent Signaling Circulation Research. 123. DOI: 10.1161/res.123.suppl_1.578 |
0.49 |
|
| 2017 |
Pera T, Deshpande DA, Ippolito M, Wang B, Gavrila A, Michael JV, Nayak AP, Tompkins E, Farrell E, Kroeze WK, Roth BL, Panettieri RA, Benovic JL, An SS, Dulin NO, et al. Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29042451 DOI: 10.1096/Fj.201700555R |
0.486 |
|
| 2017 |
Komolov KE, Benovic JL. G protein-coupled receptor kinases: Past, present and future. Cellular Signalling. PMID 28711719 DOI: 10.1016/J.Cellsig.2017.07.004 |
0.496 |
|
| 2017 |
Komolov KE, Du Y, Duc NM, Betz RM, Rodrigues JPGLM, Leib RD, Patra D, Skiniotis G, Adams CM, Dror RO, Chung KY, Kobilka BK, Benovic JL. Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5. Cell. 169: 407-421.e16. PMID 28431242 DOI: 10.1016/J.Cell.2017.03.047 |
0.679 |
|
| 2017 |
Luo J, Busillo JM, Stumm R, Benovic JL. G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of Beta-Arrestin. Molecular Pharmacology. PMID 28331048 DOI: 10.1124/Mol.116.106468 |
0.589 |
|
| 2017 |
Chua V, Lapadula D, Randolph C, Benovic JL, Wedegaertner P, Aplin AE. Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma. Molecular Cancer Research : McR. PMID 28223438 DOI: 10.1158/1541-7786.Mcr-17-0007 |
0.32 |
|
| 2017 |
Wang J, Luo J, Aryal DK, Wetzel WC, Nass R, Benovic JL. G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans. The Journal of Biological Chemistry. PMID 28213524 DOI: 10.1074/Jbc.M116.760850 |
0.412 |
|
| 2016 |
Carr R, Schilling J, Song J, Carter RL, Du Y, Yoo SM, Traynham CJ, Koch WJ, Cheung JY, Tilley DG, Benovic JL. β-arrestin-biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction. Proceedings of the National Academy of Sciences of the United States of America. PMID 27354517 DOI: 10.1073/Pnas.1606267113 |
0.538 |
|
| 2016 |
DeRita RM, Zerlanko B, Singh A, Lu H, Iozzo RV, Benovic JL, Languino LR. c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase Are Enriched into Prostate Cancer Cell Exosomes. Journal of Cellular Biochemistry. PMID 27232975 DOI: 10.1002/Jcb.25611 |
0.481 |
|
| 2016 |
Tian X, Irannejad R, Bowman SL, Du Y, Puthenveedu MA, von Zastrow M, Benovic JL. The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor. The Journal of Biological Chemistry. PMID 27226565 DOI: 10.1074/Jbc.M116.716589 |
0.523 |
|
| 2016 |
Carr R, Benovic JL. From biased signalling to polypharmacology: unlocking unique intracellular signalling using pepducins. Biochemical Society Transactions. 44: 555-61. PMID 27068969 DOI: 10.1042/Bst20150230 |
0.34 |
|
| 2015 |
Carr R, Koziol-White C, Zhang J, Lam H, Ahn SS, Tall GG, Panettieri RA, Benovic JL. Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms. Molecular Pharmacology. PMID 26464325 DOI: 10.1124/Mol.115.100339 |
0.498 |
|
| 2015 |
Benovic JL. Structural biology: Arresting developments in receptor signalling. Nature. 523: 538-9. PMID 26200346 DOI: 10.1038/Nature14637 |
0.467 |
|
| 2015 |
Komolov KE, Bhardwaj A, Benovic JL. Atomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor Kinases. The Journal of Biological Chemistry. 290: 20629-47. PMID 26032409 DOI: 10.1074/Jbc.M115.647297 |
0.484 |
|
| 2015 |
Augello MA, Berman-Booty LD, Carr R, Yoshida A, Dean JL, Schiewer MJ, Feng FY, Tomlins SA, Gao E, Koch WJ, Benovic JL, Diehl JA, Knudsen KE. Consequence of the tumor-associated conversion to cyclin D1b. Embo Molecular Medicine. 7: 628-47. PMID 25787974 DOI: 10.15252/Emmm.201404242 |
0.437 |
|
| 2015 |
Martinez-Martin N, Viejo-Borbolla A, Martín R, Blanco S, Benovic JL, Thelen M, Alcamí A. Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization. Nature Communications. 6: 6163. PMID 25625471 DOI: 10.1038/Ncomms7163 |
0.388 |
|
| 2015 |
Benovic JL, Armstrong RN. New frontiers in kinases. Biochemistry. 54: 1. PMID 25517407 DOI: 10.1021/Bi501533E |
0.342 |
|
| 2014 |
Carr R, Du Y, Quoyer J, Panettieri RA, Janz JM, Bouvier M, Kobilka BK, Benovic JL. Development and characterization of pepducins as Gs-biased allosteric agonists. The Journal of Biological Chemistry. 289: 35668-84. PMID 25395624 DOI: 10.1074/Jbc.M114.618819 |
0.753 |
|
| 2014 |
Kang DS, Tian X, Benovic JL. Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking. Current Opinion in Cell Biology. 27: 63-71. PMID 24680432 DOI: 10.1016/J.Ceb.2013.11.005 |
0.504 |
|
| 2014 |
Benovic JL, von Zastrow M. Editorial overview: Cell regulation: The ins and outs of G protein-coupled receptors. Current Opinion in Cell Biology. 27: v-vi. PMID 24529749 DOI: 10.1016/J.Ceb.2014.01.009 |
0.504 |
|
| 2014 |
Tian X, Kang DS, Benovic JL. β-arrestins and G protein-coupled receptor trafficking. Handbook of Experimental Pharmacology. 219: 173-86. PMID 24292830 DOI: 10.1007/978-3-642-41199-1_9 |
0.53 |
|
| 2014 |
Kook S, Zhan X, Cleghorn WM, Benovic JL, Gurevich VV, Gurevich EV. Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death Cell Death and Differentiation. 21: 172-184. PMID 24141717 DOI: 10.1038/Cdd.2013.143 |
0.367 |
|
| 2013 |
Quoyer J, Janz JM, Luo J, Ren Y, Armando S, Lukashova V, Benovic JL, Carlson KE, Hunt SW, Bouvier M. Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein. Proceedings of the National Academy of Sciences of the United States of America. 110: E5088-97. PMID 24309376 DOI: 10.1073/Pnas.1312515110 |
0.647 |
|
| 2013 |
So CH, Michal A, Komolov KE, Luo J, Benovic JL. G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation. Molecular Biology of the Cell. 24: 2795-806. PMID 23904266 DOI: 10.1091/Mbc.E13-01-0013 |
0.839 |
|
| 2013 |
Kang DS, Tian X, Benovic JL. β-Arrestins and G protein-coupled receptor trafficking. Methods in Enzymology. 521: 91-108. PMID 23351735 DOI: 10.1016/B978-0-12-391862-8.00005-3 |
0.46 |
|
| 2013 |
Chen YJ, Oldfield S, Butcher AJ, Tobin AB, Saxena K, Gurevich VV, Benovic JL, Henderson G, Kelly E. Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptor. Journal of Neurochemistry. 124: 189-99. PMID 23106126 DOI: 10.1111/Jnc.12071 |
0.506 |
|
| 2012 |
Benovic JL. G-protein-coupled receptors signal victory. Cell. 151: 1148-50. PMID 23201142 DOI: 10.1016/J.Cell.2012.11.015 |
0.497 |
|
| 2012 |
Li G, Zhou Q, Yu Y, Chen L, Shi Y, Luo J, Benovic J, Lu J, Zhou N. Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization. Molecular Pharmacology. 82: 1150-61. PMID 22962331 DOI: 10.1124/Mol.112.081307 |
0.548 |
|
| 2012 |
So CH, Michal AM, Mashayekhi R, Benovic JL. G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition. The Journal of Biological Chemistry. 287: 17088-99. PMID 22467873 DOI: 10.1074/Jbc.M112.353854 |
0.831 |
|
| 2012 |
Wood JF, Wang J, Benovic JL, Ferkey DM. Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in vivo. The Journal of Biological Chemistry. 287: 12634-44. PMID 22375004 DOI: 10.1074/Jbc.M111.336818 |
0.492 |
|
| 2012 |
Michal AM, So CH, Beeharry N, Shankar H, Mashayekhi R, Yen TJ, Benovic JL. G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression. The Journal of Biological Chemistry. 287: 6928-40. PMID 22223642 DOI: 10.1074/Jbc.M111.298034 |
0.837 |
|
| 2012 |
Woerner BM, Luo J, Brown KR, Jackson E, Dahiya SM, Mischel P, Benovic JL, Piwnica-Worms D, Rubin JB. Suppression of G-protein-coupled receptor kinase 3 expression is a feature of classical GBM that is required for maximal growth. Molecular Cancer Research : McR. 10: 156-66. PMID 22086906 DOI: 10.1158/1541-7786.Mcr-11-0411 |
0.517 |
|
| 2011 |
Bychkov ER, Ahmed MR, Gurevich VV, Benovic JL, Gurevich EV. Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder. Neurobiology of Disease. 44: 248-58. PMID 21784156 DOI: 10.1016/J.Nbd.2011.07.009 |
0.367 |
|
| 2011 |
Barker BL, Benovic JL. G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. Biochemistry. 50: 6933-41. PMID 21728385 DOI: 10.1021/Bi2005202 |
0.583 |
|
| 2011 |
Michal AM, Peck AR, Tran TH, Liu C, Rimm DL, Rui H, Benovic JL. Differential expression of arrestins is a predictor of breast cancer progression and survival. Breast Cancer Research and Treatment. 130: 791-807. PMID 21318602 DOI: 10.1007/S10549-011-1374-9 |
0.765 |
|
| 2010 |
Sosa MS, Lopez-Haber C, Yang C, Wang H, Lemmon MA, Busillo JM, Luo J, Benovic JL, Klein-Szanto A, Yagi H, Gutkind JS, Parsons RE, Kazanietz MG. Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer. Molecular Cell. 40: 877-92. PMID 21172654 DOI: 10.1016/J.Molcel.2010.11.029 |
0.399 |
|
| 2010 |
Huang H, He X, Deng X, Li G, Ying G, Sun Y, Shi L, Benovic JL, Zhou N. Bombyx adipokinetic hormone receptor activates extracellular signal-regulated kinase 1 and 2 via G protein-dependent PKA and PKC but β-arrestin-independent pathways. Biochemistry. 49: 10862-72. PMID 21126059 DOI: 10.1021/Bi1014425 |
0.49 |
|
| 2010 |
Chen XP, Yang W, Fan Y, Luo JS, Hong K, Wang Z, Yan JF, Chen X, Lu JX, Benovic JL, Zhou NM. Structural determinants in the second intracellular loop of the human cannabinoid CB1 receptor mediate selective coupling to G(s) and G(i). British Journal of Pharmacology. 161: 1817-34. PMID 20735408 DOI: 10.1111/J.1476-5381.2010.01006.X |
0.466 |
|
| 2010 |
Li G, Shi Y, Huang H, Zhang Y, Wu K, Luo J, Sun Y, Lu J, Benovic JL, Zhou N. Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3. The Journal of Biological Chemistry. 285: 22605-18. PMID 20460384 DOI: 10.1074/Jbc.M109.087213 |
0.564 |
|
| 2010 |
Palmitessa A, Benovic JL. Arrestin and the multi-PDZ domain-containing protein MPZ-1 interact with phosphatase and tensin homolog (PTEN) and regulate Caenorhabditis elegans longevity. The Journal of Biological Chemistry. 285: 15187-200. PMID 20207731 DOI: 10.1074/Jbc.M110.104612 |
0.416 |
|
| 2010 |
Mundell SJ, Matharu AL, Nisar S, Palmer TM, Benovic JL, Kelly E. Deletion of the distal COOH-terminus of the A2B adenosine receptor switches internalization to an arrestin- and clathrin-independent pathway and inhibits recycling. British Journal of Pharmacology. 159: 518-33. PMID 20128803 DOI: 10.1111/j.1476-5381.2009.00598.x |
0.36 |
|
| 2010 |
Shankar H, Michal A, Kern RC, Kang DS, Gurevich VV, Benovic JL. Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function. The Journal of Biological Chemistry. 285: 8316-29. PMID 20056609 DOI: 10.1074/Jbc.M109.062521 |
0.785 |
|
| 2010 |
Busillo JM, Armando S, Sengupta R, Meucci O, Bouvier M, Benovic JL. Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. The Journal of Biological Chemistry. 285: 7805-17. PMID 20048153 DOI: 10.1074/Jbc.M109.091173 |
0.643 |
|
| 2010 |
Patial S, Luo J, Porter KJ, Benovic JL, Parameswaran N. G-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα. The Biochemical Journal. 425: 169-78. PMID 19796012 DOI: 10.1042/Bj20090908 |
0.477 |
|
| 2009 |
Pao CS, Barker BL, Benovic JL. Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation. Biochemistry. 48: 7325-33. PMID 19715378 DOI: 10.1021/Bi900408G |
0.599 |
|
| 2009 |
Kang DS, Kern RC, Puthenveedu MA, von Zastrow M, Williams JC, Benovic JL. Structure of an arrestin2-clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking. The Journal of Biological Chemistry. 284: 29860-72. PMID 19710023 DOI: 10.1074/Jbc.M109.023366 |
0.658 |
|
| 2009 |
Barthet G, Carrat G, Cassier E, Barker B, Gaven F, Pillot M, Framery B, Pellissier LP, Augier J, Kang DS, Claeysen S, Reiter E, Banères JL, Benovic JL, Marin P, et al. Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling. The Embo Journal. 28: 2706-18. PMID 19661922 DOI: 10.1038/Emboj.2009.215 |
0.751 |
|
| 2009 |
Kern RC, Kang DS, Benovic JL. Arrestin2/clathrin interaction is regulated by key N- and C-terminal regions in arrestin2. Biochemistry. 48: 7190-200. PMID 19555118 DOI: 10.1021/Bi900369C |
0.653 |
|
| 2009 |
Lakshmikanthan V, Zou L, Kim JI, Michal A, Nie Z, Messias NC, Benovic JL, Daaka Y. Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 106: 9379-84. PMID 19458261 DOI: 10.1073/Pnas.0900258106 |
0.768 |
|
| 2009 |
Zhu C, Huang H, Hua R, Li G, Yang D, Luo J, Zhang C, Shi L, Benovic JL, Zhou N. Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori. Febs Letters. 583: 1463-8. PMID 19345219 DOI: 10.1016/J.Febslet.2009.03.060 |
0.455 |
|
| 2009 |
Yang M, He RL, Benovic JL, Ye RD. beta-Arrestin1 interacts with the G-protein subunits beta1gamma2 and promotes beta1gamma2-dependent Akt signalling for NF-kappaB activation. The Biochemical Journal. 417: 287-96. PMID 18729826 DOI: 10.1042/Bj20081561 |
0.419 |
|
| 2008 |
Luo J, Busillo JM, Benovic JL. M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms. Molecular Pharmacology. 74: 338-47. PMID 18388243 DOI: 10.1124/Mol.107.044750 |
0.491 |
|
| 2008 |
Ahmed MR, Gurevich VV, Dalby KN, Benovic JL, Gurevich EV. Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signal-regulated kinase activation. The Journal of Pharmacology and Experimental Therapeutics. 325: 276-83. PMID 18178904 DOI: 10.1124/Jpet.107.131987 |
0.489 |
|
| 2008 |
Ahmed MR, Bychkov E, Gurevich VV, Benovic JL, Gurevich EV. Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment. Journal of Neurochemistry. 104: 1622-36. PMID 17996024 DOI: 10.1111/J.1471-4159.2007.05104.X |
0.38 |
|
| 2008 |
Bychkov ER, Gurevich VV, Joyce JN, Benovic JL, Gurevich EV. Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia Neurobiology of Aging. 29: 379-396. PMID 17125886 DOI: 10.1016/J.Neurobiolaging.2006.10.012 |
0.426 |
|
| 2007 |
Bhandari D, Trejo J, Benovic JL, Marchese A. Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4. The Journal of Biological Chemistry. 282: 36971-9. PMID 17947233 DOI: 10.1074/Jbc.M705085200 |
0.471 |
|
| 2007 |
Jiang X, Benovic JL, Wedegaertner PB. Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A. Molecular Biology of the Cell. 18: 2960-9. PMID 17538017 DOI: 10.1091/Mbc.E07-01-0013 |
0.434 |
|
| 2007 |
Busillo JM, Benovic JL. Regulation of CXCR4 signaling. Biochimica Et Biophysica Acta. 1768: 952-63. PMID 17169327 DOI: 10.1016/J.Bbamem.2006.11.002 |
0.448 |
|
| 2007 |
Moore CA, Milano SK, Benovic JL. Regulation of receptor trafficking by GRKs and arrestins. Annual Review of Physiology. 69: 451-82. PMID 17037978 DOI: 10.1146/Annurev.Physiol.69.022405.154712 |
0.554 |
|
| 2006 |
Parameswaran N, Pao CS, Leonhard KS, Kang DS, Kratz M, Ley SC, Benovic JL. Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages. The Journal of Biological Chemistry. 281: 34159-70. PMID 16980301 DOI: 10.1074/Jbc.M605376200 |
0.496 |
|
| 2006 |
Mundell SJ, Luo J, Benovic JL, Conley PB, Poole AW. Distinct clathrin-coated pits sort different G protein-coupled receptor cargo. Traffic (Copenhagen, Denmark). 7: 1420-31. PMID 16899088 DOI: 10.1111/J.1600-0854.2006.00469.X |
0.527 |
|
| 2006 |
Lodowski DT, Tesmer VM, Benovic JL, Tesmer JJ. The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs. The Journal of Biological Chemistry. 281: 16785-93. PMID 16613860 DOI: 10.1074/Jbc.M601327200 |
0.547 |
|
| 2006 |
Milano SK, Kim YM, Stefano FP, Benovic JL, Brenner C. Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding. The Journal of Biological Chemistry. 281: 9812-23. PMID 16439357 DOI: 10.1074/Jbc.M512703200 |
0.355 |
|
| 2005 |
Rutherford C, Ord-Shrimpton FU, Sands WA, Pediani JD, Benovic JL, McGrath JC, Palmer TM. Phosphorylation-independent internalisation and desensitisation of the human sphingosine-1-phosphate receptor S1P3. Cellular Signalling. 17: 997-1009. PMID 15894172 DOI: 10.1016/J.Cellsig.2004.11.018 |
0.521 |
|
| 2005 |
Guigoni C, Aubert I, Li Q, Gurevich VV, Benovic JL, Ferry S, Mach U, Stark H, Leriche L, HÃ¥kansson K, Bioulac BH, Gross CE, Sokoloff P, Fisone G, Gurevich EV, et al. Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors. Parkinsonism & Related Disorders. 11: S25-9. PMID 15885624 DOI: 10.1016/J.Parkreldis.2004.11.005 |
0.382 |
|
| 2005 |
Palmitessa A, Hess HA, Bany IA, Kim YM, Koelle MR, Benovic JL. Caenorhabditus elegans arrestin regulates neural G protein signaling and olfactory adaptation and recovery. The Journal of Biological Chemistry. 280: 24649-62. PMID 15878875 DOI: 10.1074/Jbc.M502637200 |
0.458 |
|
| 2005 |
Bezard E, Gross CE, Qin L, Gurevich VV, Benovic JL, Gurevich EV. L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain. Neurobiology of Disease. 18: 323-35. PMID 15686961 DOI: 10.1016/J.Nbd.2004.10.005 |
0.447 |
|
| 2005 |
Hardy AR, Conley PB, Luo J, Benovic JL, Poole AW, Mundell SJ. P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms. Blood. 105: 3552-60. PMID 15665114 DOI: 10.1182/Blood-2004-07-2893 |
0.529 |
|
| 2005 |
Pao CS, Benovic JL. Structure/function analysis of alpha2A-adrenergic receptor interaction with G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 280: 11052-8. PMID 15653687 DOI: 10.1074/Jbc.M412996200 |
0.58 |
|
| 2005 |
Naik S, Billington CK, Pascual RM, Deshpande DA, Stefano FP, Kohout TA, Eckman DM, Benovic JL, Penn RB. Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling. The Journal of Biological Chemistry. 280: 8722-32. PMID 15590629 DOI: 10.1074/Jbc.M413014200 |
0.802 |
|
| 2005 |
Iwata K, Luo J, Penn RB, Benovic JL. Bimodal regulation of the human H1 histamine receptor by G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 280: 2197-204. PMID 15542600 DOI: 10.1074/Jbc.M408834200 |
0.564 |
|
| 2004 |
Gurevich EV, Benovic JL, Gurevich VV. Arrestin2 expression selectively increases during neural differentiation. Journal of Neurochemistry. 91: 1404-16. PMID 15584917 DOI: 10.1111/J.1471-4159.2004.02830.X |
0.459 |
|
| 2004 |
Day PW, Wedegaertner PB, Benovic JL. Analysis of G-protein-coupled receptor kinase RGS homology domains. Methods in Enzymology. 390: 295-310. PMID 15488185 DOI: 10.1016/S0076-6879(04)90019-5 |
0.497 |
|
| 2004 |
Marchese A, Benovic JL. Ubiquitination of G-protein-coupled receptors. Methods in Molecular Biology (Clifton, N.J.). 259: 299-305. PMID 15250500 DOI: 10.1385/1-59259-754-8:299 |
0.515 |
|
| 2004 |
Thiyagarajan MM, Stracquatanio RP, Pronin AN, Evanko DS, Benovic JL, Wedegaertner PB. A predicted amphipathic helix mediates plasma membrane localization of GRK5. The Journal of Biological Chemistry. 279: 17989-95. PMID 14976207 DOI: 10.1074/Jbc.M310738200 |
0.393 |
|
| 2004 |
Vishnivetskiy SA, Hosey MM, Benovic JL, Gurevich VV. Mapping the arrestin-receptor interface. Structural elements responsible for receptor specificity of arrestin proteins. The Journal of Biological Chemistry. 279: 1262-8. PMID 14530255 DOI: 10.1074/Jbc.M308834200 |
0.552 |
|
| 2003 |
Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL. The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4. Developmental Cell. 5: 709-22. PMID 14602072 DOI: 10.1016/S1534-5807(03)00321-6 |
0.448 |
|
| 2003 |
Luo J, Benovic JL. G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation. The Journal of Biological Chemistry. 278: 50908-14. PMID 14557268 DOI: 10.1074/Jbc.M307637200 |
0.492 |
|
| 2003 |
Noble B, Kallal LA, Pausch MH, Benovic JL. Development of a yeast bioassay to characterize G protein-coupled receptor kinases. Identification of an NH2-terminal region essential for receptor phosphorylation. The Journal of Biological Chemistry. 278: 47466-76. PMID 14507916 DOI: 10.1074/Jbc.M308257200 |
0.585 |
|
| 2003 |
Day PW, Carman CV, Sterne-Marr R, Benovic JL, Wedegaertner PB. Differential interaction of GRK2 with members of the G alpha q family. Biochemistry. 42: 9176-84. PMID 12885252 DOI: 10.1021/Bi034442+ |
0.646 |
|
| 2003 |
Marchese A, Chen C, Kim YM, Benovic JL. The ins and outs of G protein-coupled receptor trafficking. Trends in Biochemical Sciences. 28: 369-76. PMID 12878004 DOI: 10.1016/S0968-0004(03)00134-8 |
0.507 |
|
| 2002 |
Benovic JL. Novel beta2-adrenergic receptor signaling pathways. The Journal of Allergy and Clinical Immunology. 110: S229-35. PMID 12464929 DOI: 10.1067/Mai.2002.129370 |
0.575 |
|
| 2002 |
Pao CS, Benovic JL. Phosphorylation-independent desensitization of G protein-coupled receptors? Science's Stke : Signal Transduction Knowledge Environment. 2002: pe42. PMID 12372852 DOI: 10.1126/Stke.2002.153.Pe42 |
0.582 |
|
| 2002 |
DeGraff JL, Gurevich VV, Benovic JL. The third intracellular loop of alpha 2-adrenergic receptors determines subtype specificity of arrestin interaction. The Journal of Biological Chemistry. 277: 43247-52. PMID 12205092 DOI: 10.1074/Jbc.M207495200 |
0.387 |
|
| 2002 |
Kim YM, Benovic JL. Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking. The Journal of Biological Chemistry. 277: 30760-8. PMID 12070169 DOI: 10.1074/Jbc.M204528200 |
0.521 |
|
| 2002 |
Kim YM, Barak LS, Caron MG, Benovic JL. Regulation of arrestin-3 phosphorylation by casein kinase II. The Journal of Biological Chemistry. 277: 16837-46. PMID 11877451 DOI: 10.1074/Jbc.M201379200 |
0.68 |
|
| 2002 |
Milano SK, Pace HC, Kim YM, Brenner C, Benovic JL. Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis. Biochemistry. 41: 3321-8. PMID 11876640 DOI: 10.1021/Bi015905J |
0.506 |
|
| 2002 |
Gurevich EV, Benovic JL, Gurevich VV. Arrestin2 and arrestin3 are differentially expressed in the rat brain during postnatal development Neuroscience. 109: 421-436. PMID 11823056 DOI: 10.1016/S0306-4522(01)00511-5 |
0.479 |
|
| 2002 |
Watterson KR, Johnston E, Chalmers C, Pronin A, Cook SJ, Benovic JL, Palmer TM. Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 277: 5767-77. PMID 11741892 DOI: 10.1074/Jbc.M110647200 |
0.564 |
|
| 2002 |
Mundell SJ, Orsini MJ, Benovic JL. Characterization of arrestin expression and function. Methods in Enzymology. 343: 600-11. PMID 11665594 DOI: 10.1016/S0076-6879(02)43160-6 |
0.512 |
|
| 2002 |
Pronin AN, Loudon RP, Benovic JL. Characterization of G protein-coupled receptor kinases. Methods in Enzymology. 343: 547-59. PMID 11665591 DOI: 10.1016/S0076-6879(02)43157-6 |
0.59 |
|
| 2002 |
Kallal L, Benovic JL. Fluorescence microscopy techniques for the study of G protein-coupled receptor trafficking. Methods in Enzymology. 343: 492-506. PMID 11665588 DOI: 10.1016/S0076-6879(02)43154-0 |
0.42 |
|
| 2001 |
Gray JA, Sheffler DJ, Bhatnagar A, Woods JA, Hufeisen SJ, Benovic JL, Roth BL. Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine(2A) receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells. Molecular Pharmacology. 60: 1020-30. PMID 11641430 DOI: 10.1124/Mol.60.5.1020 |
0.426 |
|
| 2001 |
Marchese A, Benovic JL. Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting. The Journal of Biological Chemistry. 276: 45509-12. PMID 11641392 DOI: 10.1074/Jbc.C100527200 |
0.521 |
|
| 2001 |
Penn RB, Pascual RM, Kim YM, Mundell SJ, Krymskaya VP, Panettieri RA, Benovic JL. Arrestin specificity for G protein-coupled receptors in human airway smooth muscle. The Journal of Biological Chemistry. 276: 32648-56. PMID 11418617 DOI: 10.1074/Jbc.M104143200 |
0.587 |
|
| 2001 |
Matharu AL, Mundell SJ, Benovic JL, Kelly E. Rapid Agonist-induced Desensitization and Internalization of the A 2B Adenosine Receptor is Mediated by a Serine Residue Close to the COOH Terminus Journal of Biological Chemistry. 276: 30199-30207. PMID 11333255 DOI: 10.1074/Jbc.M010650200 |
0.506 |
|
| 2001 |
Mundell SJ, Olah ME, Panettieri J, Benovic JL, Penn RB. Regulation of g protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine American Journal of Respiratory Cell and Molecular Biology. 24: 155-163. PMID 11159049 DOI: 10.1165/Ajrcmb.24.2.4243 |
0.473 |
|
| 2001 |
Shui Z, Khan IA, Haga T, Benovic JL, Boyett MR. Control of the cardiac muscarinic K+ channel by beta-arrestin 2. The Journal of Biological Chemistry. 276: 11691-7. PMID 11152693 DOI: 10.1074/Jbc.M011007200 |
0.377 |
|
| 2001 |
Penn RB, Pronin AN, Benovic JL. Regulation of G protein-coupled receptor kinases. Trends in Cardiovascular Medicine. 10: 81-9. PMID 11150735 DOI: 10.1016/S1050-1738(00)00053-0 |
0.58 |
|
| 2001 |
Parent JL, Labrecque P, Driss Rochdi M, Benovic JL. Role of the differentially spliced carboxyl terminus in thromboxane A2 receptor trafficking: identification of a distinct motif for tonic internalization. The Journal of Biological Chemistry. 276: 7079-85. PMID 11112783 DOI: 10.1074/Jbc.M009375200 |
0.522 |
|
| 2001 |
Bhatnagar A, Willins DL, Gray JA, Woods J, Benovic JL, Roth BL. The dynamin-dependent, arrestin-independent internalization of 5-hydroxytryptamine 2A (5-HT2A) serotonin receptors reveals differential sorting of arrestins and 5-HT2A receptors during endocytosis. The Journal of Biological Chemistry. 276: 8269-77. PMID 11069907 DOI: 10.1074/Jbc.M006968200 |
0.419 |
|
| 2000 |
Yu X, Zhang M, Kyker K, Patterson E, Benovic JL, Kem DC. Ischemic inactivation of G protein-coupled receptor kinase and altered desensitization of canine cardiac beta-adrenergic receptors. Circulation. 102: 2535-40. PMID 11076829 DOI: 10.1161/01.CIR.102.20.2535 |
0.483 |
|
| 2000 |
Mundell SJ, Matharu AL, Kelly E, Benovic JL. Arrestin isoforms dictate differential kinetics of A2(B) adenosine receptor trafficking Biochemistry. 39: 12828-12836. PMID 11041847 DOI: 10.1021/Bi0010928 |
0.327 |
|
| 2000 |
Krymskaya VP, Orsini MJ, Eszterhas AJ, Brodbeck KC, Benovic JL, Panettieri RA, Penn RB. Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 23: 546-54. PMID 11017921 DOI: 10.1165/Ajrcmb.23.4.4115 |
0.505 |
|
| 2000 |
Li JG, Benovic JL, Liu-Chen LY. Mechanisms of agonist-induced down-regulation of the human kappa-opioid receptor: internalization is required for down-regulation. Molecular Pharmacology. 58: 795-801. PMID 10999950 |
0.332 |
|
| 2000 |
Aiyar N, Disa J, Dang K, Pronin AN, Benovic JL, Nambi P. Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors. European Journal of Pharmacology. 403: 1-7. PMID 10969137 DOI: 10.1016/S0014-2999(00)00419-2 |
0.713 |
|
| 2000 |
Tiruppathi C, Yan W, Sandoval R, Naqvi T, Pronin AN, Benovic JL, Malik AB. G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 7440-5. PMID 10861009 DOI: 10.1073/Pnas.97.13.7440 |
0.328 |
|
| 2000 |
Pronin AN, Morris AJ, Surguchov A, Benovic JL. Synucleins are a novel class of substrates for G protein-coupled receptor kinases Journal of Biological Chemistry. 275: 26515-26522. PMID 10852916 DOI: 10.1074/Jbc.M003542200 |
0.564 |
|
| 2000 |
Santini F, Penn RB, Gagnon AW, Benovic JL, Keen JH. Selective recruitment of arrestin-3 to clathrin coated pits upon stimulation of G protein-coupled receptors Journal of Cell Science. 113: 2463-2470. PMID 10852825 |
0.47 |
|
| 2000 |
Kallal L, Benovic JL. Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking Trends in Pharmacological Sciences. 21: 175-180. PMID 10785651 DOI: 10.1016/S0165-6147(00)01477-2 |
0.493 |
|
| 2000 |
Mundell SJ, Benovic JL. Selective regulation of endogenous G protein-coupled receptors by arrestins in HEK293 cells Journal of Biological Chemistry. 275: 12900-12908. PMID 10777589 DOI: 10.1074/Jbc.275.17.12900 |
0.57 |
|
| 2000 |
Carman CV, Barak LS, Chen C, Liu-Chen LY, Onorato JJ, Kennedy SP, Caron MG, Benovic JL. Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 275: 10443-52. PMID 10744734 DOI: 10.1074/jbc.275.14.10443 |
0.788 |
|
| 2000 |
Wu G, Bogatkevich GS, Mukhin YV, Benovic JL, Hildebrandt JD, Lanier SM. Identification of Gbetagamma binding sites in the third intracellular loop of the M(3)-muscarinic receptor and their role in receptor regulation. The Journal of Biological Chemistry. 275: 9026-34. PMID 10722752 DOI: 10.1074/Jbc.275.12.9026 |
0.335 |
|
| 2000 |
Gros R, Chorazyczewski J, Meek MD, Benovic JL, Ferguson SS, Feldman RD. G-Protein-coupled receptor kinase activity in hypertension : increased vascular and lymphocyte G-protein receptor kinase-2 protein expression. Hypertension. 35: 38-42. PMID 10642272 DOI: 10.1161/01.Hyp.35.1.38 |
0.385 |
|
| 2000 |
Eckhart AD, Duncan SJ, Penn RB, Benovic JL, Lefkowitz RJ, Koch WJ. Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart. Circulation Research. 86: 43-50. PMID 10625304 DOI: 10.1161/01.Res.86.1.43 |
0.635 |
|
| 2000 |
Li J, Benovic JL, Liu-Chen L. Mechanisms of Agonist-Induced Down-Regulation of the Human κ-Opioid Receptor: Internalization Is Required for Down-Regulation Molecular Pharmacology. 58: 795-801. DOI: 10.1124/Mol.58.4.795 |
0.444 |
|
| 1999 |
Orsini MJ, Krymskaya VP, Eszterhas AJ, Benovic JL, Panettieri RA, Penn RB. MAPK superfamily activation in human airway smooth muscle: mitogenesis requires prolonged p42/p44 activation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L479-L488. PMID 29592441 DOI: 10.1152/Ajplung.1999.277.3.L479 |
0.348 |
|
| 1999 |
Carman CV, Parent JL, Day PW, Pronin AN, Sternweis PM, Wedegaertner PB, Gilman AG, Benovic JL, Kozasa T. Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2. The Journal of Biological Chemistry. 274: 34483-92. PMID 10567430 DOI: 10.1074/Jbc.274.48.34483 |
0.721 |
|
| 1999 |
Willets JM, Parent JL, Benovic JL, Kelly E. Selective reduction in A2 adenosine receptor desensitization following antisense-induced suppression of G protein-coupled receptor kinase 2 expression. Journal of Neurochemistry. 73: 1781-9. PMID 10537035 DOI: 10.1046/j.1471-4159.1999.0731781.x |
0.483 |
|
| 1999 |
Billington CK, Hall IP, Mundell SJ, Parent JL, Panettieri RA, Benovic JL, Penn RB. Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 21: 597-606. PMID 10536119 DOI: 10.1165/Ajrcmb.21.5.3759 |
0.432 |
|
| 1999 |
Orsini MJ, Parent JL, Mundell SJ, Marchese A, Benovic JL. Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization. The Journal of Biological Chemistry. 274: 31076-86. PMID 10521508 DOI: 10.1074/Jbc.274.43.31076 |
0.509 |
|
| 1999 |
Mundell SJ, Loudon RP, Benovic JL. Characterization of G protein-coupled receptor regulation in antisense mRNA-expressing cells with reduced arrestin levels Biochemistry. 38: 8723-8732. PMID 10393547 DOI: 10.1021/Bi990361V |
0.532 |
|
| 1999 |
Lazari MDFM, Liu X, Nakamura K, Benovic JL, Ascoli M. Role of G protein-coupled receptor kinases on the agonist-induced phosphorylation and internalization of the follitropin receptor Molecular Endocrinology. 13: 866-878. PMID 10379886 DOI: 10.1210/Mend.13.6.0289 |
0.53 |
|
| 1999 |
Gros R, Tan CM, Chorazyczewski J, Kelvin DJ, Benovic JL, Feldman RD. G-protein-coupled receptor kinase expression in hypertension. Clinical Pharmacology and Therapeutics. 65: 545-51. PMID 10340920 DOI: 10.1016/S0009-9236(99)70074-3 |
0.476 |
|
| 1999 |
Wang YX, Dhulipala PDK, Li L, Benovic JL, Kotlikoff MI. Coupling of M2 muscarinic receptors to membrane ion channels via phosphoinositide 3-kinase γ and atypical protein kinase C Journal of Biological Chemistry. 274: 13859-13864. PMID 10318793 DOI: 10.1074/Jbc.274.20.13859 |
0.479 |
|
| 1999 |
Gelber EI, Kroeze WK, Willins DL, Gray JA, Sinar CA, Hyde EG, Gurevich V, Benovic J, Roth BL. Structure and function of the third intracellular loop of the 5-hydroxytryptamine2A receptor: the third intracellular loop is alpha-helical and binds purified arrestins. Journal of Neurochemistry. 72: 2206-14. PMID 10217304 DOI: 10.1046/J.1471-4159.1999.0722206.X |
0.552 |
|
| 1999 |
Li JG, Luo LY, Krupnick JG, Benovic JL, Liu-Chen LY. U50,488H-induced internalization of the human kappa opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. Kappa receptor internalization is not required for mitogen-activated protein kinase activation. The Journal of Biological Chemistry. 274: 12087-94. PMID 10207034 DOI: 10.1074/jbc.274.17.12087 |
0.451 |
|
| 1999 |
DeGraff JL, Gagnon AW, Benovic JL, Orsini MJ. Role of arrestins in endocytosis and signaling of alpha2-adrenergic receptor subtypes. The Journal of Biological Chemistry. 274: 11253-9. PMID 10196213 DOI: 10.1074/Jbc.274.16.11253 |
0.493 |
|
| 1999 |
Parent JL, Labrecque P, Orsini MJ, Benovic JL. Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced cooh terminus in agonist-promoted receptor internalization. The Journal of Biological Chemistry. 274: 8941-8. PMID 10085139 DOI: 10.1074/Jbc.274.13.8941 |
0.543 |
|
| 1999 |
Carman CV, Lisanti MP, Benovic JL. Regulation of G protein-coupled receptor kinases by caveolin Journal of Biological Chemistry. 274: 8858-8864. PMID 10085129 DOI: 10.1074/Jbc.274.13.8858 |
0.731 |
|
| 1999 |
Hosey MM, Pals-Rylaarsdam R, Lee KB, Roseberry AG, Benovic JL, Gurevich VV, Bünemann M. Molecular events associated with the regulation of signaling by M2 muscarinic receptors. Life Sciences. 64: 363-8. PMID 10069497 DOI: 10.1016/S0024-3205(98)00575-X |
0.424 |
|
| 1999 |
Gaidarov I, Krupnick JG, Falck JR, Benovic JL, Keen JH. Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding Embo Journal. 18: 871-881. PMID 10022830 DOI: 10.1093/Emboj/18.4.871 |
0.546 |
|
| 1999 |
Mukherjee S, Palczewski K, Gurevich V, Benovic JL, Banga JP, Hunzicker-Dunn M. A direct role for arrestins in desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes. Proceedings of the National Academy of Sciences of the United States of America. 96: 493-8. PMID 9892661 DOI: 10.1073/Pnas.96.2.493 |
0.406 |
|
| 1999 |
Lee K, Pals-Rylaarsdam R, Benovic J, Hosey M. Arrestin-independent internalization of muscarinic cholinergic receptors Life Sciences. 64: 575. DOI: 10.1016/S0024-3205(99)90505-2 |
0.393 |
|
| 1998 |
Orsini MJ, Benovic JL. Characterization of dominant negative arrestins that inhibit β2- adrenergic receptor internalization by distinct mechanisms Journal of Biological Chemistry. 273: 34616-34622. PMID 9852134 DOI: 10.1074/Jbc.273.51.34616 |
0.559 |
|
| 1998 |
Pronin AN, Carman CV, Benovic JL. Structure-function analysis of G protein-coupled receptor kinase-5: Role of the carboxyl terminus in kinase regulation Journal of Biological Chemistry. 273: 31510-31518. PMID 9813065 DOI: 10.1074/Jbc.273.47.31510 |
0.749 |
|
| 1998 |
Mundell SJ, Luty JS, Willets J, Benovic JL, Kelly E. Enhanced expression of G protein-coupled receptor kinase 2 selectively increases the sensitivity of A(2A) adenosine receptors to agonist-induced desensitization British Journal of Pharmacology. 125: 347-356. PMID 9786508 DOI: 10.1038/Sj.Bjp.0702081 |
0.564 |
|
| 1998 |
Levay K, Satpaev DK, Pronin AN, Benovic JL, Slepak VZ. Localization of the sites for Ca2+-binding proteins on G protein- coupled receptor kinases Biochemistry. 37: 13650-13659. PMID 9753452 DOI: 10.1021/Bi980998Z |
0.402 |
|
| 1998 |
Nakamura K, Krupnick JG, Benovic JL, Ascoli M. Signaling and phosphorylation-impaired mutants of the rat follitropin receptor reveal an activation- and phosphorylation-independent but arrestin- dependent pathway for internalization Journal of Biological Chemistry. 273: 24346-24354. PMID 9733722 DOI: 10.1074/Jbc.273.38.24346 |
0.484 |
|
| 1998 |
Penn RB, Panettieri RA, Benovic JL. Mechanisms of acute desensitization of the β2AR-adenylyl cyclase pathway in human airway smooth muscle American Journal of Respiratory Cell and Molecular Biology. 19: 338-348. PMID 9698608 DOI: 10.1165/Ajrcmb.19.2.3025 |
0.452 |
|
| 1998 |
Carman CV, Benovic JL. G-protein-coupled receptors: Turn-ons and turn-offs Current Opinion in Neurobiology. 8: 335-344. PMID 9687355 DOI: 10.1016/S0959-4388(98)80058-5 |
0.771 |
|
| 1998 |
Carman CV, Som T, Kim CM, Benovic JL. Binding and phosphorylation of tubulin by G protein-coupled receptor kinases Journal of Biological Chemistry. 273: 20308-20316. PMID 9685381 DOI: 10.1074/Jbc.273.32.20308 |
0.764 |
|
| 1998 |
Lazari MF, Bertrand JE, Nakamura K, Liu X, Krupnick JG, Benovic JL, Ascoli M. Mutation of individual serine residues in the C-terminal tail of the lutropin/choriogonadotropin receptor reveal distinct structural requirements for agonist-induced uncoupling and agonist-induced internalization. The Journal of Biological Chemistry. 273: 18316-24. PMID 9660797 DOI: 10.1074/Jbc.273.29.18316 |
0.362 |
|
| 1998 |
Krupnick JG, Benovic JL. The role of receptor kinases and arrestins in G protein-coupled receptor regulation Annual Review of Pharmacology and Toxicology. 38: 289-319. PMID 9597157 DOI: 10.1146/Annurev.Pharmtox.38.1.289 |
0.596 |
|
| 1998 |
Lee KB, Pals-Rylaarsdam R, Benovic JL, Hosey MM. Arrestin-independent internalization of the m1, m3, and m4 subtypes of muscarinic cholinergic receptors Journal of Biological Chemistry. 273: 12967-12972. PMID 9582330 DOI: 10.1074/Jbc.273.21.12967 |
0.3 |
|
| 1998 |
Wu G, Benovic JL, Hildebrandt JD, Lanier SM. Receptor docking sites for G-protein βγ subunits. Implications for signal regulation Journal of Biological Chemistry. 273: 7197-7200. PMID 9516410 DOI: 10.1074/Jbc.273.13.7197 |
0.39 |
|
| 1998 |
Gagnon AW, Kallal L, Benovic JL. Role of clathrin-mediated endocytosis in agonist-induced down-regulation of the β2-adrenergic receptor Journal of Biological Chemistry. 273: 6976-6981. PMID 9507004 DOI: 10.1074/Jbc.273.12.6976 |
0.48 |
|
| 1998 |
Kallal L, Gagnon AW, Penn RB, Benovic JL. Visualization of agonist-induced sequestration and down-regulation of a green fluorescent protein-tagged β2-adrenergic receptor Journal of Biological Chemistry. 273: 322-328. PMID 9417083 DOI: 10.1074/Jbc.273.1.322 |
0.517 |
|
| 1998 |
Wu G, Benovic JL, Hildebrandt JD, Lanier SM. Receptor docking sites for G-protein:βγ subunits: Implications for signal regulation Faseb Journal. 12. |
0.406 |
|
| 1997 |
Krupnick JG, Santini F, Gagnon AW, Keen JH, Benovic JL. Modulation of the arrestin-clathrin interaction in cells: Characterization of β-arrestin dominant-negative mutants Journal of Biological Chemistry. 272: 32507-32512. PMID 9405462 DOI: 10.1074/Jbc.272.51.32507 |
0.44 |
|
| 1997 |
Fukayama S, Kong G, Benovic JL, Meurer E, Tashjian AH. β-adrenergic receptor kinase-1 acutely regulates PTH/PTHrP receptor signalling in human osteoblastlike cells Cellular Signalling. 9: 469-474. PMID 9376230 DOI: 10.1016/S0898-6568(97)00044-2 |
0.545 |
|
| 1997 |
Gurevich VV, Pals-Rylaarsdam R, Benovic JL, Hosey MM, Onorato JJ. Agonist-receptor-arrestin, an alternative ternary complex with high agonist affinity Journal of Biological Chemistry. 272: 28849-28852. PMID 9360951 DOI: 10.1074/Jbc.272.46.28849 |
0.558 |
|
| 1997 |
Loudon RP, Benovic JL. Altered activity of palmitoylation-deficient and isoprenylated forms of the G protein-coupled receptor kinase GRK6 Journal of Biological Chemistry. 272: 27422-27427. PMID 9341194 DOI: 10.1074/Jbc.272.43.27422 |
0.513 |
|
| 1997 |
Goodman OB, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH, Benovic JL. Role of arrestins in G-protein-coupled receptor endocytosis. Advances in Pharmacology (San Diego, Calif.). 42: 429-33. PMID 9327931 DOI: 10.1016/S1054-3589(08)60780-2 |
0.581 |
|
| 1997 |
Pals-Rylaarsdam R, Gurevich VV, Lee KB, Ptasienski JA, Benovic JL, Hosey MM. Internalization of the m2 muscarinic acetylcholine receptor. Arrestin- independent and -dependent pathways Journal of Biological Chemistry. 272: 23682-23689. PMID 9295310 DOI: 10.1074/Jbc.272.38.23682 |
0.489 |
|
| 1997 |
Krupnick JG, Gurevich VV, Benovic JL. Mechanism of quenching of phototransduction: Binding competition between arrestin and transducin for phosphorhodopsin Journal of Biological Chemistry. 272: 18125-18131. PMID 9218446 DOI: 10.1074/Jbc.272.29.18125 |
0.447 |
|
| 1997 |
Wu G, Krupnick JG, Benovic JL, Lanier SM. Interaction of Arrestins with intracellular domains of muscarinic and α 2-adrenergic receptors Journal of Biological Chemistry. 272: 17836-17842. PMID 9211939 DOI: 10.1074/Jbc.272.28.17836 |
0.346 |
|
| 1997 |
Gray-Keller MP, Detwiler PB, Benovic JL, Gurevich VV. Arrestin with a single amino acid substitution quenches light-activated rhodopsin in a phosphorylation-independent fashion. Biochemistry. 36: 7058-63. PMID 9188704 DOI: 10.1021/Bi963110K |
0.433 |
|
| 1997 |
Mundell SJ, Benovic JL, Kelly E. A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization Molecular Pharmacology. 51: 991-998. PMID 9187265 DOI: 10.1124/Mol.51.6.991 |
0.545 |
|
| 1997 |
Kelsen SG, Anakwe OO, Aksoy MO, Reddy PJ, Dhanesekaran N, Penn R, Benovic JL. Chronic effects of catecholamines on the beta 2-adrenoreceptor system in cultured human airway epithelial cells. The American Journal of Physiology. 272: L916-24. PMID 9176257 DOI: 10.1152/ajplung.1997.272.5.l916 |
0.301 |
|
| 1997 |
Goodman OB, Krupnick JG, Gurevich VV, Benovic JL, Keen JH. Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain. The Journal of Biological Chemistry. 272: 15017-22. PMID 9169477 DOI: 10.1074/Jbc.272.23.15017 |
0.37 |
|
| 1997 |
Krupnick JG, Goodman OB, Keen JH, Benovic JL. Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxyl terminus Journal of Biological Chemistry. 272: 15011-15016. PMID 9169476 DOI: 10.1074/Jbc.272.23.15011 |
0.42 |
|
| 1997 |
Gros R, Benovic JL, Tan CM, Feldman RD. G-protein-coupled receptor kinase activity is increased in hypertension Journal of Clinical Investigation. 99: 2087-2093. PMID 9151780 DOI: 10.1172/Jci119381 |
0.541 |
|
| 1997 |
Gagnon AW, Benovic JL. Identification and chromosomal localization of a processed pseudogene of human GRK6 Gene. 184: 13-19. PMID 9016947 DOI: 10.1016/S0378-1119(96)00567-7 |
0.369 |
|
| 1997 |
Gurevich VV, Benovic JL. Mechanism of phosphorylation-recognition by visual arrestin and the transition of arrestin into a high affinity binding state Molecular Pharmacology. 51: 161-169. PMID 9016359 DOI: 10.1124/Mol.51.1.161 |
0.427 |
|
| 1997 |
Pronin AN, Benovic JL. Regulation of the G protein-coupled receptor kinase GRK5 by protein kinase C Journal of Biological Chemistry. 272: 3806-3812. PMID 9013639 DOI: 10.1074/Jbc.272.6.3806 |
0.582 |
|
| 1997 |
Pronin AN, Satpaev DK, Slepak VZ, Benovic JL. Regulation of g protein-coupled receptor kinases by calmodulin and localization of the calmodulin binding domain Faseb Journal. 11. DOI: 10.1074/Jbc.272.29.18273 |
0.555 |
|
| 1997 |
Gagnon AW, Kallal L, Benovic JL. Role of arrestins in agonist-mediated downregulation of the 3 2-adrenergic receptor Faseb Journal. 11. |
0.39 |
|
| 1997 |
Aiyar N, Pisa J, Dang K, Pronin AN, Benovic JL, Nambi P. Desensitization of recombinant porcine calcitonin gene-related peptide (CGRP) receptor: A possible role for G-protein-coupled receptor kinase 5 (GRK5) Faseb Journal. 11. |
0.445 |
|
| 1996 |
Hosey MM, DebBurman SK, Pals-Rylaarsdam R, Richardson RM, Benovic JL. The role of G-protein coupled receptor kinases in the regulation of muscarinic cholinergic receptors. Progress in Brain Research. 109: 169-79. PMID 9009704 DOI: 10.1016/S0079-6123(08)62099-3 |
0.589 |
|
| 1996 |
Loudon RP, Perussia B, Benovic JL. Differentially regulated expression of the G-protein-coupled receptor kinases, βARK and GRK6, during myelomonocytic cell development in vitro Blood. 88: 4547-4557. PMID 8977246 DOI: 10.1182/Blood.V88.12.4547.Bloodjournal88124547 |
0.518 |
|
| 1996 |
Penn RB, Frielle T, McCullough JR, Aberg G, Benovic JL. Comparison of R-, S-, and RS-Albuterol Interaction with Human β1- and β2-Adrenergic Receptors Clinical Reviews in Allergy and Immunology. 14: 37-45. PMID 8866170 DOI: 10.1007/Bf02772201 |
0.748 |
|
| 1996 |
Goodman OB, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH, Benovic JL. Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature. 383: 447-50. PMID 8837779 DOI: 10.1038/383447A0 |
0.54 |
|
| 1996 |
DebBurman SK, Ptasienski J, Benovic JL, Hosey MM. G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits. The Journal of Biological Chemistry. 271: 22552-62. PMID 8798423 DOI: 10.1074/Jbc.271.37.22552 |
0.547 |
|
| 1996 |
Palmer TM, Benovic JL, Stiles GL. Molecular basis for subtype-specific desensitization of inhibitory adenosine receptors: Analysis of a chimeric A1-A3 adenosine receptor Journal of Biological Chemistry. 271: 15272-15278. PMID 8663009 DOI: 10.1074/Jbc.271.25.15272 |
0.753 |
|
| 1996 |
Diviani D, Lattion AL, Larbi N, Kunapuli P, Pronin A, Benovic JL, Cotecchia S. Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the alpha1B-adrenergic receptor. The Journal of Biological Chemistry. 271: 5049-58. PMID 8617782 DOI: 10.1074/Jbc.271.9.5049 |
0.775 |
|
| 1996 |
Murga C, Ruiz-Gómez A, García-Higuera I, Kim CM, Benovic JL, Mayor F. High affinity binding of beta-adrenergic receptor kinase to microsomal membranes. Modulation of the activity of bound kinase by heterotrimeric G protein activation. The Journal of Biological Chemistry. 271: 985-94. PMID 8557715 DOI: 10.1074/Jbc.271.2.985 |
0.69 |
|
| 1996 |
Pronin AN, Benovic JL. The g protein-coupled receptor kinase grk5 is a target for regulation by PKC Faseb Journal. 10. |
0.468 |
|
| 1996 |
M-Zhang, Cofie DQ, Turnbaugh DT, Benovic JL, Patterson ES, Kem DC. The effect of ischemia on cardiac g-protein coupled receptor kinases Journal of Investigative Medicine. 44. |
0.353 |
|
| 1995 |
Hosey MM, Benovic JL, DebBurman SK, Richardson RM. Multiple mechanisms involving protein phosphorylation are linked to desensitization of muscarinic receptors. Life Sciences. 56: 951-5. PMID 10188798 DOI: 10.1016/0024-3205(95)00033-3 |
0.486 |
|
| 1995 |
Kelsen SG, Higgins NC, Zhou S, Mardini IA, Benovic JL. Expression and function of the beta-adrenergic receptor coupled-adenylyl cyclase system on human airway epithelial cells. American Journal of Respiratory and Critical Care Medicine. 152: 1774-83. PMID 8520736 DOI: 10.1164/Ajrccm.152.6.8520736 |
0.434 |
|
| 1995 |
Zhang J, Zhang J, Benovic JL, Sugai M, Wetzker R, Gout I, Rittenhouse SE. Sequestration of a G-protein beta gamma subunit or ADP-ribosylation of Rho can inhibit thrombin-induced activation of platelet phosphoinositide 3-kinases. The Journal of Biological Chemistry. 270: 6589-94. PMID 7896797 DOI: 10.1074/Jbc.270.12.6589 |
0.389 |
|
| 1995 |
Gurevich VV, Benovic JL. Visual arrestin binding to rhodopsin: Diverse functional roles of positively charged residues within the phosphorylation-recognition region of arrestin Journal of Biological Chemistry. 270: 6010-6016. PMID 7890732 DOI: 10.1074/Jbc.270.11.6010 |
0.398 |
|
| 1995 |
DebBurman SK, Ptasienski J, Boetticher E, Lomasney JW, Benovic JL, Hosey MM. Lipid-mediated regulation of G protein-coupled receptor kinases 2 and 3. The Journal of Biological Chemistry. 270: 5742-7. PMID 7890702 DOI: 10.1074/Jbc.270.11.5742 |
0.743 |
|
| 1995 |
Anakwe O, Zhou S, Benovic J, Aksoy M, Kelsen SG. Interleukins impair beta-adrenergic receptor adenylate cyclase (beta AR-AC) system function in human airway epithelial cells. Chest. 107: 138S-139S. PMID 7874996 DOI: 10.1378/chest.107.3_Supplement.138S |
0.323 |
|
| 1995 |
Debburman SK, Kunapuli P, Benovic JL, Hosey MM. Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases. Molecular Pharmacology. 47: 224-33. PMID 7870029 |
0.495 |
|
| 1995 |
Prossnitz ER, Kim CM, Benovic JL, Ye RD. Phosphorylation of the N-formyl peptide receptor carboxyl terminus by the G protein-coupled receptor kinase, GRK2 Journal of Biological Chemistry. 270: 1130-1137. PMID 7836371 DOI: 10.1074/Jbc.270.3.1130 |
0.544 |
|
| 1995 |
Gurevich VV, Dion SB, Onorato JJ, Ptasienski J, Kim CM, Sterne-Marr R, Hosey MM, Benovic JL. Arrestin interactions with G protein-coupled receptors: Direct binding studies of wild type and mutant arrestins with rhodopsin, β2-adrenergic, and m2 muscarinic cholinergic receptors Journal of Biological Chemistry. 270: 720-731. PMID 7822302 DOI: 10.1074/Jbc.270.2.720 |
0.567 |
|
| 1995 |
Bullrich F, Druck T, Kunapuli P, Gomez J, Gripp KW, Schlegelberger B, Lasota J, Aronson M, Cannizzaro LA, Huebner K, Benovic JL. Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6 Cytogenetic and Genome Research. 70: 250-254. PMID 7789183 DOI: 10.1159/000134045 |
0.51 |
|
| 1995 |
Saito M, Frielle T, Benovic JL, Ledeen RW. Modulation by GM1 ganglioside of β1-adrenergic receptor-induced cyclic AMP formation in Sf9 cells Bba - Molecular Cell Research. 1267: 1-5. PMID 7779864 DOI: 10.1016/0167-4889(95)00026-O |
0.803 |
|
| 1995 |
Onorato JJ, Gillis ME, Liu Y, Benovic JL, Ruoho AE. The beta-adrenergic receptor kinase (GRK2) is regulated by phospholipids. The Journal of Biological Chemistry. 270: 21346-53. PMID 7673171 DOI: 10.1074/Jbc.270.36.21346 |
0.565 |
|
| 1995 |
Pals-Rylaarsdam R, Xu Y, Witt-Enderby P, Benovic JL, Hosey MM. Desensitization and internalization of the m2 muscarinic acetylcholine receptor are directed by independent mechanisms Journal of Biological Chemistry. 270: 29004-29011. PMID 7499433 DOI: 10.1074/Jbc.270.48.29004 |
0.571 |
|
| 1995 |
Palmer TM, Benovic JL, Stiles GL. Agonist-dependent phosphorylation and desensitization of the rat A3 adenosine receptor: Evidence for a G-protein-coupled receptor kinase-mediated mechanism Journal of Biological Chemistry. 270: 29607-29613. PMID 7494005 DOI: 10.1074/Jbc.270.49.29607 |
0.766 |
|
| 1995 |
Sterne-Marr R, Benovic JL. Regulation of G Protein-Coupled Receptors by Receptor Kinases and Arrestins Vitamins and Hormones. 51: 193-234. DOI: 10.1016/S0083-6729(08)61039-0 |
0.561 |
|
| 1995 |
Pals-Rylaarsdam R, Benovic JL, Marlene Hosey M. Desensitization of the M2 muscarinic acetylcholine receptor: Effects of dominant-negative βARK1 Life Sciences. 56: 1031. DOI: 10.1016/0024-3205(95)93775-A |
0.414 |
|
| 1995 |
DebBurman SK, Ptasienski J, Benovic JL, Marlene Hosey M. Effects of phospholipids on agonist-dependent phosphorylation of human muscarinic acetylcholine receptors by G protein-coupled receptor kinases: An alternate mode to kinase activation? Life Sciences. 56: 1028. DOI: 10.1016/0024-3205(95)93768-A |
0.565 |
|
| 1994 |
Kunapuli P, Onorato JJ, Hosey MM, Benovic JL. Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5 Journal of Biological Chemistry. 269: 1099-1105. PMID 8288567 |
0.498 |
|
| 1994 |
Penn RB, Benovic JL. Structure of the human gene encoding the beta-adrenergic receptor kinase. The Journal of Biological Chemistry. 269: 14924-30. PMID 8195124 |
0.392 |
|
| 1994 |
Kong G, Penn R, Benovic JL. A β-adrenergic receptor kinase dominant negative mutant attenuates desensitization of the β2-adrenergic receptor Journal of Biological Chemistry. 269: 13084-13087. PMID 8175732 |
0.532 |
|
| 1994 |
Kunapuli P, Gurevich VV, Benovic JL. Phospholipid-stimulated autophosphorylation activates the G protein-coupled receptor kinase GRK5 Journal of Biological Chemistry. 269: 10209-10212. PMID 8144599 |
0.474 |
|
| 1994 |
Loudon RP, Benovic JL. Expression, purification, and characterization of the G protein-coupled receptor kinase GRK6 Journal of Biological Chemistry. 269: 22691-22697. PMID 8077221 |
0.5 |
|
| 1994 |
Penn RB, Kelsen SG, Benovic JL. Regulation of beta-agonist- and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells American Journal of Respiratory Cell and Molecular Biology. 11: 496-505. PMID 7917318 DOI: 10.1165/Ajrcmb.11.4.7917318 |
0.433 |
|
| 1994 |
Mardini IA, Higgins NC, Zhou S, Benovic JL, Kelsen SG. Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium. American Journal of Respiratory Cell and Molecular Biology. 11: 287-95. PMID 7916196 DOI: 10.1165/Ajrcmb.11.3.7916196 |
0.464 |
|
| 1994 |
Raynor K, Kong H, Heerding J, Hines J, Benovic J, Reisine T. Differential agonist modulation of the cloned opioid receptors reveals distinct cellular mechanisms of receptor regulation Regulatory Peptides. 54: 239-240. DOI: 10.1016/0167-0115(94)90478-2 |
0.529 |
|
| 1994 |
Kelsen SG, Zhou Shuangwen, Anakwe O, Mardini I, Higgins N, Benovic JL. Expression of the beta-adrenergic receptor-adenylylcyclase system in basal and columnar airway epithelial cells Am.J.Physiol.. 267. |
0.367 |
|
| 1993 |
Richardson RM, Kim C, Benovic JL, Hosey MM. Phosphorylation and desensitization of human m2 muscarinic cholinergic receptors by two isoforms of the β-adrenergic receptor kinase Journal of Biological Chemistry. 268: 13650-13656. PMID 8514797 |
0.521 |
|
| 1993 |
Ramkumar V, Kwatra M, Benovic JL, Stilesa GL. Functional consequences of A1 adenosine-receptor phosphorylation by the β-adrenergic receptor kinase Bba - Molecular Cell Research. 1179: 89-97. PMID 8399355 DOI: 10.1016/0167-4889(93)90075-Z |
0.57 |
|
| 1993 |
Kim CM, Dion SB, Onorato JJ, Benovic JL. Expression and characterization of two beta-adrenergic receptor kinase isoforms using the baculovirus expression system Receptor. 3: 39-55. PMID 8394172 |
0.362 |
|
| 1993 |
Kim CM, Dion SB, Benovic JL. Mechanism of β-adrenergic receptor kinase activation by G proteins Journal of Biological Chemistry. 268: 15412-15418. PMID 8393441 |
0.389 |
|
| 1993 |
Benovic JL, Gomez J. Molecular cloning and expression of GRK6: A new member of the G protein-coupled receptor kinase family Journal of Biological Chemistry. 268: 19521-19527. PMID 8366096 |
0.467 |
|
| 1993 |
Gurevich VV, Richardson RM, Kim CM, Hosey MM, Benovic JL. Binding of wild type and chimeric arrestins to the m2 muscarinic cholinergic receptor Journal of Biological Chemistry. 268: 16879-16882. PMID 8349577 |
0.4 |
|
| 1993 |
Chen CY, Dion SB, Kim CM, Benovic JL. β-Adrenergic receptor kinase. Agonist-dependent receptor binding promotes kinase activation Journal of Biological Chemistry. 268: 7825-7831. PMID 8096517 |
0.367 |
|
| 1993 |
Kunapuli P, Benovic JL. Cloning and expression of GRK5: A member of the G protein-coupled receptor kinase family Proceedings of the National Academy of Sciences of the United States of America. 90: 5588-5592. PMID 7685906 DOI: 10.1073/Pnas.90.12.5588 |
0.541 |
|
| 1992 |
Gomez J, Benovic JL. Molecular and regulatory properties of the adenylyl cyclase-coupled β-adrenergic receptors International Review of Cytology. 137: 1-34. PMID 1336003 DOI: 10.1016/S0074-7696(08)62598-X |
0.597 |
|
| 1992 |
Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. Science (New York, N.Y.). 257: 1264-7. PMID 1325672 DOI: 10.1126/Science.1325672 |
0.793 |
|
| 1991 |
Benovic JL, Stone WC, Huebner K, Croce C, Caron MG, Lefkowitz RJ. cDNA cloning and chromosomal localization of the human α-adrenergic receptor kinase Febs Letters. 283: 122-126. PMID 2037065 DOI: 10.1016/0014-5793(91)80568-N |
0.614 |
|
| 1991 |
Palczewskl K, Benovic JL. G-protein-coupled receptor kinases Trends in Biochemical Sciences. 16: 387-391. PMID 1664548 DOI: 10.1016/0968-0004(91)90157-Q |
0.588 |
|
| 1991 |
Benovic JL. Purification and characterization of β-adrenergic receptor kinase Methods in Enzymology. 200: 351-362. PMID 1659657 DOI: 10.1016/0076-6879(91)00152-M |
0.376 |
|
| 1991 |
Yang SD, Benovic JL, Fong YL, Caron MG, Lefkowitz RJ. Cyclic phosphorylation-dephosphorylation of rhodopsin in retina by protein kinase FA (the activator of ATP.Mg-dependent protein phosphatase) Biochemical and Biophysical Research Communications. 178: 1306-1311. PMID 1651717 DOI: 10.1016/0006-291X(91)91036-C |
0.641 |
|
| 1991 |
Onorato JJ, Palczewski K, Regan JW, Caron MG, Lefkowitz RJ, Benovic JL. Role of acidic amino acids in peptide substrates of the β-adrenergic receptor kinase and rhodopsin kinase Biochemistry®. 30: 5118-5125. PMID 1645191 DOI: 10.1021/Bi00235A002 |
0.727 |
|
| 1990 |
Collins S, Bouvier M, Lohse MJ, Benovic JL, Caron MG, Lefkowitz RJ. Mechanisms involved in adrenergic receptor desensitization. Biochemical Society Transactions. 18: 541-4. PMID 2177406 DOI: 10.1042/Bst0180541 |
0.844 |
|
| 1990 |
Benovic JL, Onorato J, Lohse MJ, Dohlman HG, Staniszewski C, Caron MG, Lefkowitz RJ. Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase. British Journal of Clinical Pharmacology. 30: 3S-12S. PMID 2176526 DOI: 10.1111/J.1365-2125.1990.Tb05462.X |
0.768 |
|
| 1990 |
Lohse MJ, Benovic JL, Codina J, Caron MG, Lefkowitz RJ. beta-Arrestin: a protein that regulates beta-adrenergic receptor function. Science (New York, N.Y.). 248: 1547-50. PMID 2163110 DOI: 10.1126/Science.2163110 |
0.696 |
|
| 1990 |
Lohse MJ, Benovic JL, Caron MG, Lefkowitz RJ. Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors. The Journal of Biological Chemistry. 265: 3202-11. PMID 2154473 |
0.608 |
|
| 1990 |
Benovic JL, Onorato JJ, Caron MG, Lefkowitz RJ. Regulation of G protein-coupled receptors by agonist-dependent phosphorylation Journal of General Physiology. 87-103. |
0.481 |
|
| 1989 |
Kwatra MM, Benovic JL, Caron MG, Lefkowitz RJ, Hosey MM. Phosphorylation of chick heart muscarinic cholinergic receptors by the β-adrenergic receptor kinase Biochemistry. 28: 4543-4547. PMID 2765501 DOI: 10.1021/Bi00437A005 |
0.745 |
|
| 1989 |
Benovic JL, DeBlasi A, Stone WC, Caron MG, Lefkowitz RJ. Β-adrenergic receptor kinase: Primary structure delineates a multigene family Science. 246: 235-240. PMID 2552582 DOI: 10.1126/Science.2552582 |
0.712 |
|
| 1989 |
Lohse MJ, Lefkowitz RJ, Caron MG, Benovic JL. Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 86: 3011-5. PMID 2541428 DOI: 10.1073/Pnas.86.9.3011 |
0.691 |
|
| 1989 |
Benovic JL, Stone WC, Caron MG, Lefkowitz RJ. Inhibition of the β-adrenergic receptor kinase by polyanions Journal of Biological Chemistry. 264: 6707-6710. PMID 2468660 |
0.378 |
|
| 1988 |
Krupinski J, Rajaram R, Lakonishok M, Benovic JL, Cerione RA. Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles Journal of Biological Chemistry. 263: 12333-12341. PMID 3137226 |
0.318 |
|
| 1988 |
Lefkowitz RJ, Kobilka BK, Benovic JL, Bouvier M, Cotecchia S, Hausdorff WP, Dohlman HG, Regan JW, Caron MG. Molecular biology of adrenergic receptors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 507-14. PMID 2855490 DOI: 10.1101/Sqb.1988.053.01.058 |
0.821 |
|
| 1988 |
Benovic JL, Bouvier M, Caron MG, Lefkowitz RJ. Regulation of adenylyl cyclase-coupled beta-adrenergic receptors. Annual Review of Cell Biology. 4: 405-28. PMID 2848553 DOI: 10.1146/Annurev.Cb.04.110188.002201 |
0.798 |
|
| 1988 |
Strasser RH, Benovic JL, Lefkowitz RJ, Caron MG. The beta-adrenergic receptor kinase: role in homologous desensitization in S49 lymphoma cells Advances in Experimental Medicine and Biology. 231: 503-517. PMID 2843012 DOI: 10.1007/978-1-4684-9042-8_43 |
0.736 |
|
| 1988 |
Caron MG, Kobilka BK, Frielle T, Bolanowski MA, Benovic JL, Lefkowitz RJ. Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors. Journal of Receptor Research. 8: 7-21. PMID 2838630 DOI: 10.3109/10799898809048975 |
0.825 |
|
| 1988 |
Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways. Endocrine Reviews. 9: 38-56. PMID 2836188 DOI: 10.1210/Edrv-9-1-38 |
0.777 |
|
| 1988 |
Benovic JL, Staniszewski C, Mayor F, Caron MG, Lefkowitz RJ. β-Adrenergic receptor kinase. Activity of partial agonists for stimulation of adenylate cyclase correlates with ability to promote receptor phosphorylation Journal of Biological Chemistry. 263: 3893-3897. PMID 2831211 |
0.484 |
|
| 1987 |
Benovic JL, Mayor F, Staniszewski C, Lefkowitz RJ, Caron MG. Purification and characterization of the beta-adrenergic receptor kinase Journal of Biological Chemistry. 262: 9026-9032. PMID 3036840 |
0.38 |
|
| 1987 |
Cerione RA, Gierschik P, Staniszewski C, Benovic JL, Codina J, Somers R, Birnbaumer L, Spiegel AM, Lefkowitz RJ, Caron MG. Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein. Biochemistry. 26: 1485-91. PMID 3032251 DOI: 10.1021/Bi00379A041 |
0.65 |
|
| 1987 |
Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Regulation of transmembrane signaling by receptor phosphorylation. Cell. 48: 913-22. PMID 3030559 DOI: 10.1016/0092-8674(87)90700-8 |
0.805 |
|
| 1987 |
Bouvier M, Leeb-Lundberg LM, Benovic JL, Caron MG, Lefkowitz RJ. Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase. The Journal of Biological Chemistry. 262: 3106-13. PMID 3029101 |
0.806 |
|
| 1987 |
Benovic JL, Staniszewski C, Cerione RA, Codina J, Lefkowitz RJ, Caron MG. The mammalian βadrenergic receptor: Structural and functional characterization of the carbohydrate moiety Journal of Receptors and Signal Transduction. 7: 257-281. PMID 2887651 DOI: 10.3109/10799898709054989 |
0.738 |
|
| 1987 |
Mayor F, Benovic JL, Caron MG, Lefkowitz RJ. Somatostatin induces translocation of the β-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells Journal of Biological Chemistry. 262: 6468-6471. PMID 2883186 |
0.47 |
|
| 1987 |
Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Molecular mechanisms of beta-adrenergic receptor desensitization. Advances in Experimental Medicine and Biology. 221: 253-73. PMID 2829583 DOI: 10.1007/978-1-4684-7618-7_19 |
0.799 |
|
| 1987 |
Benovic JL, Kühn H, Weyand I, Codina J, Caron MG, Lefkowitz RJ. Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein) Proceedings of the National Academy of Sciences of the United States of America. 84: 8879-8882. PMID 2827157 DOI: 10.1073/Pnas.84.24.8879 |
0.753 |
|
| 1987 |
Dohlman HG, Bouvier M, Benovic JL, Caron MG, Lefkowitz RJ. The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis. The Journal of Biological Chemistry. 262: 14282-8. PMID 2821000 |
0.762 |
|
| 1987 |
Benovic JL, Lefkowitz RJ. 10 Regulation of Receptor Function Enzymes. 18: 319-333. DOI: 10.1016/S1874-6047(08)60261-9 |
0.615 |
|
| 1986 |
Sibley DR, Strasser RH, Benovic JL, Daniel K, Lefkowitz RJ. Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution. Proceedings of the National Academy of Sciences of the United States of America. 83: 9408-12. PMID 3025843 DOI: 10.1073/Pnas.83.24.9408 |
0.793 |
|
| 1986 |
Strasser RH, Benovic JL, Caron MG, Lefkowitz RJ. β-Agonist- and prostaglandin E1-induced translocation of the β-adrenergic receptor kinase: Evidence that the kinase may act on multiple adenylate cyclase-coupled receptors Proceedings of the National Academy of Sciences of the United States of America. 83: 6362-6366. PMID 3018728 DOI: 10.1073/Pnas.83.17.6362 |
0.787 |
|
| 1986 |
Benovic JL, Mayor F, Somers RL, Caron MG, Lefkowitz RJ. Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase Nature. 321: 869-872. PMID 3014340 DOI: 10.1038/321869A0 |
0.795 |
|
| 1986 |
Dixon RA, Kobilka BK, Strader DJ, Benovic JL, Dohlman HG, Frielle T, Bolanowski MA, Bennett CD, Rands E, Diehl RE, Mumford RA, Slater EE, Sigal IS, Caron MG, Lefkowitz RJ, et al. Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. Nature. 321: 75-9. PMID 3010132 DOI: 10.1038/321075A0 |
0.816 |
|
| 1986 |
Benovic JL, Strasser RH, Caron MG, Lefkowitz RJ. β-Adrenergic receptor kinase: Identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor Proceedings of the National Academy of Sciences of the United States of America. 83: 2797-2801. PMID 2871555 DOI: 10.1073/Pnas.83.9.2797 |
0.791 |
|
| 1986 |
Lefkowitz RJ, Benovic JL, Kobilka B, Caron MG. β-Adrenergic receptors and rhodopsin: shedding new light on an old subject Trends in Pharmacological Sciences. 7: 444-448. DOI: 10.1016/0165-6147(86)90417-7 |
0.766 |
|
| 1984 |
Stiles GL, Benovic JL, Caron MG, Lefkowitz RJ. Mammalian β-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains Journal of Biological Chemistry. 259: 8655-8663. PMID 6330118 |
0.363 |
|
| 1984 |
Cerione RA, Codina J, Benovic JL, Lefkowitz RJ, Birnbaumer L, Caron MG. The mammalian β2-adrenergic receptor: Reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system Biochemistry. 23: 4519-4525. PMID 6149763 DOI: 10.1021/Bi00315A003 |
0.771 |
|
| 1984 |
Benovic JL, Shorr RGL, Caron MG, Lefkowitz RJ. The mammalian β2-adrenergic receptor: Purification and characterization Biochemistry. 23: 4510-4518. PMID 6093858 DOI: 10.1021/Bi00315A002 |
0.684 |
|
| 1984 |
Benovic JL, Cerione RA, Codina J. Deglycosylation of the pure β-adrenergic receptor Federation Proceedings. 43. |
0.374 |
|
| 1984 |
Pike LJ, Benovic JL, Caron MG, Lefkowitz RJ. Isoproterenol enhances phosphorylation of pure β-adrenergic receptor by cAMP-dependent protein kinase Federation Proceedings. 43. |
0.733 |
|
| 1983 |
Cerione RA, Strulovici B, Benovic JL, Lefkowitz RJ, Caron MG. Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase Nature. 306: 562-566. PMID 6316161 DOI: 10.1038/306562A0 |
0.765 |
|
| 1983 |
Cerione RA, Strulovici B, Benovic JL, Strader CD, Caron MG, Lefkowitz RJ. Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system. Proceedings of the National Academy of Sciences of the United States of America. 80: 4899-903. PMID 6308659 DOI: 10.1073/Pnas.80.16.4899 |
0.772 |
|
| 1983 |
Benovic JL, Stiles GL, Lefkowitz RJ, Caron MG. Photoaffinity labelling of mammalian beta-adrenergic receptors: Metal-dependent proteolysis explains apparent heterogeneity Biochemical and Biophysical Research Communications. 110: 504-511. PMID 6301455 DOI: 10.1016/0006-291X(83)91178-6 |
0.724 |
|
| 1982 |
Benovic JL, Shorr RGL, Heald SL. Purification and photoaffinity labelling of a mammalian β2 adrenergic receptor Federation Proceedings. 5205. |
0.359 |
|
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