Year |
Citation |
Score |
2022 |
Wilson DJ, DuBois RN. Role of prostaglandin E2 in the progression of gastrointestinal cancer. Cancer Prevention Research (Philadelphia, Pa.). PMID 35288737 DOI: 10.1158/1940-6207.CAPR-22-0038 |
0.34 |
|
2022 |
Wei J, Zhang J, Wang D, Cen B, Lang JD, DuBois RN. The COX-2-PGE2 pathway promotes tumor evasion in colorectal adenomas. Cancer Prevention Research (Philadelphia, Pa.). PMID 35121582 DOI: 10.1158/1940-6207.CAPR-21-0572 |
0.679 |
|
2021 |
Wang D, Cabalag CS, Clemons NJ, DuBois RN. Cyclooxygenases and Prostaglandins in Tumor Immunology and Microenvironment of Gastrointestinal Cancer. Gastroenterology. PMID 34606846 DOI: 10.1053/j.gastro.2021.09.059 |
0.379 |
|
2020 |
DuBois RN. COVID-19, Cancer Care and Prevention. Cancer Prevention Research (Philadelphia, Pa.). PMID 32958589 DOI: 10.1158/1940-6207.Capr-20-0468 |
0.341 |
|
2019 |
Cen B, Lang JD, Du Y, Wei J, Xiong Y, Bradley N, Wang D, DuBois RN. Prostaglandin E2 Induces MIR675-5p to Promote Colorectal Tumor Metastasis via Modulation of p53 Expression. Gastroenterology. PMID 31734182 DOI: 10.1053/J.Gastro.2019.11.013 |
0.684 |
|
2019 |
Wang D, Fu L, Wei J, Xiong Y, DuBois RN. PPARdelta mediates the effect of dietary fat in promoting colorectal cancer metastasis. Cancer Research. PMID 31239272 DOI: 10.1158/0008-5472.Can-19-0384 |
0.45 |
|
2018 |
Wang D, DuBois RN. Role of prostanoids in gastrointestinal cancer. The Journal of Clinical Investigation. PMID 29733297 DOI: 10.1172/Jci97953 |
0.441 |
|
2017 |
Wang D, Sun H, Wei J, Cen B, DuBois RN. CXCL1 is critical for pre-metastatic niche formation and metastasis in colorectal cancer. Cancer Research. PMID 28455419 DOI: 10.1158/0008-5472.Can-16-3199 |
0.37 |
|
2016 |
Kim SH, Park YY, Cho SN, Margalit O, Wang D, DuBois RN. Krüppel-Like Factor 12 Promotes Colorectal Cancer Growth through Early Growth Response Protein 1. Plos One. 11: e0159899. PMID 27442508 DOI: 10.1371/Journal.Pone.0159899 |
0.423 |
|
2015 |
Wang D, DuBois RN. The Role of Prostaglandin E2 in Tumor-Associated Immunosuppression. Trends in Molecular Medicine. PMID 26711015 DOI: 10.1016/J.Molmed.2015.11.003 |
0.375 |
|
2015 |
Baselga J, Bhardwaj N, Cantley LC, DeMatteo R, DuBois RN, Foti M, Gapstur SM, Hahn WC, Helman LJ, Jensen RA, Paskett ED, Lawrence TS, Lutzker SG, Szabo E. AACR Cancer Progress Report 2015. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: S1-S128. PMID 26429991 DOI: 10.1158/1078-0432.Ccr-15-1846 |
0.367 |
|
2015 |
Wang D, DuBois RN. Immunosuppression associated with chronic inflammation in the tumor microenvironment. Carcinogenesis. 36: 1085-93. PMID 26354776 DOI: 10.1093/Carcin/Bgv123 |
0.406 |
|
2015 |
Wang D, Fu L, Sun H, Guo L, DuBois RN. Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice. Gastroenterology. PMID 26261008 DOI: 10.1053/J.Gastro.2015.07.064 |
0.432 |
|
2015 |
Wang D, Fu L, Sun H, DuBois RN. Abstract 1523: Prostaglandin E2 promotes colorectal cancer stem-like cell expansion and metastasis Cancer Research. 75: 1523-1523. DOI: 10.1158/1538-7445.Am2015-1523 |
0.492 |
|
2014 |
Wang D, DuBois RN. PPARδ and PGE2 signaling pathways communicate and connect inflammation to colorectal cancer. Inflammation and Cell Signaling. 1. PMID 26290896 DOI: 10.14800/Ics.338 |
0.47 |
|
2014 |
Dubois RN. Role of inflammation and inflammatory mediators in colorectal cancer. Transactions of the American Clinical and Climatological Association. 125: 358-72; discussion 3. PMID 25125751 |
0.373 |
|
2014 |
Kim SH, Margalit O, Katoh H, Wang D, Wu H, Xia D, Holla VR, Yang P, DuBois RN. CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models. Investigational New Drugs. 32: 1105-12. PMID 25085205 DOI: 10.1007/S10637-014-0144-Z |
0.416 |
|
2014 |
Wang D, DuBois RN. Myeloid-derived suppressor cells link inflammation to cancer. Oncoimmunology. 3: e28581. PMID 25054088 DOI: 10.4161/Onci.28581 |
0.449 |
|
2014 |
Wang D, Fu L, Ning W, Guo L, Sun X, Dey SK, Chaturvedi R, Wilson KT, DuBois RN. Peroxisome proliferator-activated receptor δ promotes colonic inflammation and tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 111: 7084-9. PMID 24763687 DOI: 10.1073/Pnas.1324233111 |
0.462 |
|
2013 |
Wang D, DuBois RN. An inflammatory mediator, prostaglandin E2, in colorectal cancer. Cancer Journal (Sudbury, Mass.). 19: 502-10. PMID 24270349 DOI: 10.1097/Ppo.0000000000000003 |
0.443 |
|
2013 |
Katoh H, Wang D, Daikoku T, Sun H, Dey SK, Dubois RN. CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis. Cancer Cell. 24: 631-44. PMID 24229710 DOI: 10.1016/J.Ccr.2013.10.009 |
0.461 |
|
2013 |
Kim SH, Wang D, Park YY, Katoh H, Margalit O, Sheffer M, Wu H, Holla VR, Lee JS, DuBois RN. HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways. Cancer Letters. 341: 159-65. PMID 23916472 DOI: 10.1016/J.Canlet.2013.07.028 |
0.462 |
|
2013 |
Pirman DA, Efuet E, Ding XP, Pan Y, Tan L, Fischer SM, DuBois RN, Yang P. Changes in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometry. Plos One. 8: e61379. PMID 23658609 DOI: 10.1371/Journal.Pone.0061379 |
0.372 |
|
2013 |
Wang D, DuBois RN. Urinary PGE-M: a promising cancer biomarker. Cancer Prevention Research (Philadelphia, Pa.). 6: 507-10. PMID 23636051 DOI: 10.1158/1940-6207.Capr-13-0153 |
0.388 |
|
2013 |
Charo C, Holla V, Arumugam T, Hwang R, Yang P, Dubois RN, Menter DG, Logsdon CD, Ramachandran V. Prostaglandin E2 regulates pancreatic stellate cell activity via the EP4 receptor. Pancreas. 42: 467-74. PMID 23090667 DOI: 10.1097/Mpa.0B013E318264D0F8 |
0.33 |
|
2013 |
Wang D, DuBois RN. The role of anti-inflammatory drugs in colorectal cancer. Annual Review of Medicine. 64: 131-44. PMID 23020877 DOI: 10.1146/Annurev-Med-112211-154330 |
0.418 |
|
2013 |
Wang D, Margalit O, DuBois RN. Metronomic topotecan for colorectal cancer: a promising new option. Gut. 62: 190-1. PMID 22684481 DOI: 10.1136/Gutjnl-2012-302410 |
0.329 |
|
2013 |
DuBois RN. Abstract PL05-01: Inflammatory mediators, tumor microenvironment, and progression of colorectal cancer Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Pl05-01 |
0.467 |
|
2013 |
Katoh H, Wang D, Kim S, DuBois RN. Abstract 1417: CXCR2 plays critical roles in colitis and colitis-associated cancer through trafficking of myeloid-derived suppressor cells. Cancer Research. 73: 1417-1417. DOI: 10.1158/1538-7445.Am2013-1417 |
0.46 |
|
2013 |
Charo C, Holla V, Arumugam T, Hwang R, Yang P, Dubois RN, Menter DG, Logsdon CD, Ramachandran V. PGE2 Regulates Pancreatic Stellate Cell Activity Via The EP4 Receptor Pancreatology. 13. DOI: 10.1016/J.Pan.2012.12.121 |
0.333 |
|
2012 |
Margalit O, Wang D, Dubois RN. PPARγ agonists target aromatase via both PGE2 and BRCA1. Cancer Prevention Research (Philadelphia, Pa.). 5: 1169-72. PMID 23041473 DOI: 10.1158/1940-6207.Capr-12-0365 |
0.362 |
|
2012 |
Cantley LC, Dalton WS, DuBois RN, Finn OJ, Futreal PA, Golub TR, Hait WN, Lozano G, Maris JM, Nelson WG, Sawyers CL, Schreiber SL, Spitz MR, Steeg PS. AACR Cancer Progress Report 2012. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: S1-100. PMID 22977188 DOI: 10.1158/1078-0432.Ccr-12-2891 |
0.379 |
|
2012 |
Ross W, Lynch P, Raju G, Rodriguez A, Burke T, Hafemeister L, Hawk E, Wu X, Dubois RN, Mishra L. Biomarkers, bundled payments, and colorectal cancer care. Genes & Cancer. 3: 16-22. PMID 22893787 DOI: 10.1177/1947601912448958 |
0.34 |
|
2012 |
Menter DG, Dubois RN. Prostaglandins in cancer cell adhesion, migration, and invasion. International Journal of Cell Biology. 2012: 723419. PMID 22505934 DOI: 10.1155/2012/723419 |
0.41 |
|
2012 |
Wang D, Dubois RN. Associations between obesity and cancer: the role of fatty acid synthase. Journal of the National Cancer Institute. 104: 343-5. PMID 22312133 DOI: 10.1093/Jnci/Djs010 |
0.391 |
|
2012 |
Wang D, Dubois RN. Epoxyeicosatrienoic acids: a double-edged sword in cardiovascular diseases and cancer. The Journal of Clinical Investigation. 122: 19-22. PMID 22182836 DOI: 10.1172/Jci61453 |
0.326 |
|
2012 |
Ding Q, Chang CJ, Xie X, Xia W, Yang JY, Wang SC, Wang Y, Xia J, Chen L, Cai C, Li H, Yen CJ, Kuo HP, Lee DF, Lang J, ... ... DuBois RN, et al. Erratum: APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis (Journal of Clinical Investigation (2012) 122, 1 (419) DOI:10.1172/JCI61734) Journal of Clinical Investigation. 122. DOI: 10.1172/Jci61734 |
0.332 |
|
2012 |
DuBois RN, Wang D. Abstract PL02-03: Inflammatory Mediators and Colorectal Cancer Progression Cancer Prevention Research. 5. DOI: 10.1158/1940-6207.Prev-12-Pl02-03 |
0.471 |
|
2012 |
Hawk ET, Menter DG, Patterson S, Swank MW, DuBois RN. Abstract 3251: Linking prostaglandin E2 signaling, lipid rafts, and DNA protein kinase Cancer Research. 72: 3251-3251. DOI: 10.1158/1538-7445.Am2012-3251 |
0.405 |
|
2012 |
Wang D, Guo L, Ning W, Wu H, Chaturved R, Wilson K, DuBois RN. Abstract 1519: Peroxisome proliferator-activated receptor ≤ promotes colonic inflammation and inflammation-associated tumorigenesis Cancer Research. 72: 1519-1519. DOI: 10.1158/1538-7445.Am2012-1519 |
0.466 |
|
2011 |
Wang D, Xia D, Dubois RN. The Crosstalk of PTGS2 and EGF Signaling Pathways in Colorectal Cancer. Cancers. 3: 3894-908. PMID 24213116 DOI: 10.3390/Cancers3043894 |
0.457 |
|
2011 |
Ding Q, Chang CJ, Xie X, Xia W, Yang JY, Wang SC, Wang Y, Xia J, Chen L, Cai C, Li H, Yen CJ, Kuo HP, Lee DF, Lang J, ... ... Dubois RN, et al. APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. The Journal of Clinical Investigation. 121: 4526-36. PMID 21985787 DOI: 10.1172/Jci45008 |
0.414 |
|
2011 |
Kim SH, Park YY, Kim SW, Lee JS, Wang D, DuBois RN. ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression. Cancer Research. 71: 7010-20. PMID 21937683 DOI: 10.1158/0008-5472.Can-11-1262 |
0.51 |
|
2011 |
Wang D, Ning W, Xie D, Guo L, DuBois RN. Peroxisome proliferator-activated receptor δ confers resistance to peroxisome proliferator-activated receptor γ-induced apoptosis in colorectal cancer cells. Oncogene. 31: 1013-23. PMID 21765467 DOI: 10.1038/Onc.2011.299 |
0.432 |
|
2011 |
Holla VR, Wu H, Shi Q, Menter DG, DuBois RN. Nuclear orphan receptor NR4A2 modulates fatty acid oxidation pathways in colorectal cancer. The Journal of Biological Chemistry. 286: 30003-9. PMID 21757690 DOI: 10.1074/Jbc.M110.184697 |
0.433 |
|
2011 |
Wang D, Guo L, Ning W, DuBois RN. Abstract A43: PPARδ promotes colonic inflammation and inflammation-associated tumorigenesis Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-A43 |
0.424 |
|
2011 |
Xia D, Wang D, Kim S, DuBois RN. Abstract 89: Prostaglandin E2 promotes intestinal tumor growth via DNA methylation Cancer Research. 71: 89-89. DOI: 10.1158/1538-7445.Am2011-89 |
0.385 |
|
2011 |
Kim S, Park Y, Kim S, Lee J, Wang D, DuBois RN. Abstract 399: Elevation of angiopoietin-like protein 4 by PGE2 and hypoxia promotes colorectal cancer progression Cancer Research. 71: 399-399. DOI: 10.1158/1538-7445.Am2011-399 |
0.504 |
|
2010 |
Peddareddigari VG, Wang D, Dubois RN. The tumor microenvironment in colorectal carcinogenesis. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 3: 149-66. PMID 21209781 DOI: 10.1007/S12307-010-0038-3 |
0.419 |
|
2010 |
Wang D, DuBois RN. Therapeutic potential of peroxisome proliferator-activated receptors in chronic inflammation and colorectal cancer. Gastroenterology Clinics of North America. 39: 697-707. PMID 20951925 DOI: 10.1016/J.Gtc.2010.08.014 |
0.438 |
|
2010 |
Kim SH, Xia D, Kim SW, Holla V, Menter DG, Dubois RN. Human enhancer of filamentation 1 Is a mediator of hypoxia-inducible factor-1alpha-mediated migration in colorectal carcinoma cells. Cancer Research. 70: 4054-63. PMID 20442290 DOI: 10.1158/0008-5472.Can-09-2110 |
0.384 |
|
2010 |
Speirs CK, Jernigan KK, Kim SH, Cha YI, Lin F, Sepich DS, DuBois RN, Lee E, Solnica-Krezel L. Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization. Development (Cambridge, England). 137: 1327-37. PMID 20332150 DOI: 10.1242/Dev.045971 |
0.781 |
|
2010 |
Menter DG, Schilsky RL, DuBois RN. Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 1384-90. PMID 20179228 DOI: 10.1158/1078-0432.Ccr-09-0788 |
0.42 |
|
2010 |
Wang D, Dubois RN. Eicosanoids and cancer. Nature Reviews. Cancer. 10: 181-93. PMID 20168319 DOI: 10.1038/Nrc2809 |
0.441 |
|
2010 |
Xia D, Holla VR, Wang D, Menter DG, DuBois RN. HEF1 is a crucial mediator of the proliferative effects of prostaglandin E(2) on colon cancer cells. Cancer Research. 70: 824-31. PMID 20068165 DOI: 10.1158/0008-5472.Can-09-2105 |
0.479 |
|
2010 |
Wang D, DuBois RN. The Role of COX-2 in Intestinal Inflammation and Colorectal Cancer Oncogene. 29: 781-788. PMID 19946329 DOI: 10.1038/Onc.2009.421 |
0.439 |
|
2010 |
Xia D, Wang D, Menter DG, DuBois RN. Abstract B39: Prostaglandin E2 induces human enhancer of filamentation 1 to promote the cell motility of colorectal carcinoma cells Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-B39 |
0.461 |
|
2010 |
Xia D, Menter DG, DuBois RN. Abstract 5298: Human enhancer of filamentation 1 induction by Prostaglandin E2 enhances the cell motility of colorectal cancer cells Cancer Research. 70: 5298-5298. DOI: 10.1158/1538-7445.Am10-5298 |
0.475 |
|
2009 |
Wang D, Dubois RN, Richmond A. The role of chemokines in intestinal inflammation and cancer. Current Opinion in Pharmacology. 9: 688-96. PMID 19734090 DOI: 10.1016/J.Coph.2009.08.003 |
0.318 |
|
2008 |
Holla VR, Backlund MG, Yang P, Newman RA, DuBois RN. Regulation of prostaglandin transporters in colorectal neoplasia. Cancer Prevention Research (Philadelphia, Pa.). 1: 93-9. PMID 19138942 DOI: 10.1158/1940-6207.Capr-07-0009 |
0.429 |
|
2008 |
Backlund MG, Mann JR, Holla VR, Shi Q, Daikoku T, Dey SK, DuBois RN. Repression of 15-hydroxyprostaglandin dehydrogenase involves histone deacetylase 2 and snail in colorectal cancer. Cancer Research. 68: 9331-7. PMID 19010907 DOI: 10.1158/0008-5472.Can-08-2893 |
0.45 |
|
2008 |
Wang D, Wang H, Ning W, Backlund MG, Dey SK, DuBois RN. Loss of cannabinoid receptor 1 accelerates intestinal tumor growth. Cancer Research. 68: 6468-76. PMID 18676872 DOI: 10.1158/0008-5472.Can-08-0896 |
0.498 |
|
2008 |
Pedchenko TV, Gonzalez AL, Wang D, DuBois RN, Massion PP. Peroxisome proliferator-activated receptor beta/delta expression and activation in lung cancer. American Journal of Respiratory Cell and Molecular Biology. 39: 689-96. PMID 18566335 DOI: 10.1165/Rcmb.2007-0426Oc |
0.424 |
|
2008 |
Wang D, Dubois RN. Peroxisome proliferator-activated receptors and progression of colorectal cancer. Ppar Research. 2008: 931074. PMID 18551185 DOI: 10.1155/2008/931074 |
0.433 |
|
2008 |
Wang D, DuBois RN. Pro-inflammatory prostaglandins and progression of colorectal cancer. Cancer Letters. 267: 197-203. PMID 18406516 DOI: 10.1016/J.Canlet.2008.03.004 |
0.455 |
|
2007 |
Wang D, DuBois RN. Measurement of eicosanoids in cancer tissues. Methods in Enzymology. 433: 27-50. PMID 17954227 DOI: 10.1016/S0076-6879(07)33002-4 |
0.396 |
|
2007 |
Buchanan FG, Holla V, Katkuri S, Matta P, DuBois RN. Targeting cyclooxygenase-2 and the epidermal growth factor receptor for the prevention and treatment of intestinal cancer. Cancer Research. 67: 9380-8. PMID 17909047 DOI: 10.1158/0008-5472.Can-07-0710 |
0.46 |
|
2007 |
Yang L, Amann JM, Kikuchi T, Porta R, Guix M, Gonzalez A, Park KH, Billheimer D, Arteaga CL, Tai HH, DuBois R, Carbone DP, Johnson DH. Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer. Cancer Research. 67: 5587-93. PMID 17575121 DOI: 10.1158/0008-5472.Can-06-2287 |
0.398 |
|
2007 |
Daikoku T, Tranguch S, Chakrabarty A, Wang D, Khabele D, Orsulic S, Morrow JD, Dubois RN, Dey SK. Extracellular signal-regulated kinase is a target of cyclooxygenase-1-peroxisome proliferator-activated receptor-delta signaling in epithelial ovarian cancer. Cancer Research. 67: 5285-92. PMID 17545608 DOI: 10.1158/0008-5472.Can-07-0828 |
0.478 |
|
2007 |
O'Dwyer PJ, Eckhardt SG, Haller DG, Tepper J, Ahnen D, Hamilton S, Benson AB, Rothenberg M, Petrelli N, Lenz HJ, Diasio R, DuBois R, Sargent D, Sloan J, Johnson CD, et al. Priorities in colorectal cancer research: recommendations from the Gastrointestinal Scientific Leadership Council of the Coalition of Cancer Cooperative Groups. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 2313-21. PMID 17538178 DOI: 10.1200/Jco.2006.08.6900 |
0.367 |
|
2007 |
Horikawa Y, Otaka M, Komatsu K, Jin M, Odashima M, Wada I, Matsuhashi T, Ohba R, Oyake J, Hatakeyama N, Dubois RN, Watanabe S. MEK activation suppresses CPT11-induced apoptosis in rat intestinal epithelial cells through a COX-2-dependent mechanism. Digestive Diseases and Sciences. 52: 2757-65. PMID 17393318 DOI: 10.1007/S10620-007-9798-0 |
0.41 |
|
2007 |
Wang D, DuBois RN. Inflammatory mediators and nuclear receptor signaling in colorectal cancer. Cell Cycle (Georgetown, Tex.). 6: 682-5. PMID 17374999 DOI: 10.4161/Cc.6.6.4030 |
0.515 |
|
2007 |
Cha YI, DuBois RN. NSAIDs and cancer prevention: targets downstream of COX-2. Annual Review of Medicine. 58: 239-52. PMID 17100552 DOI: 10.1146/Annurev.Med.57.121304.131253 |
0.804 |
|
2006 |
Wang D, Wang H, Guo Y, Ning W, Katkuri S, Wahli W, Desvergne B, Dey SK, DuBois RN. Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression. Proceedings of the National Academy of Sciences of the United States of America. 103: 19069-74. PMID 17148604 DOI: 10.1073/Pnas.0607948103 |
0.479 |
|
2006 |
Komatsu K, Buchanan FG, Otaka M, Jin M, Odashima M, Horikawa Y, Watanabe S, Dubois RN. Gene expression profiling following constitutive activation of MEK1 and transformation of rat intestinal epithelial cells. Molecular Cancer. 5: 63. PMID 17112382 DOI: 10.1186/1476-4598-5-63 |
0.35 |
|
2006 |
Mann JR, Backlund MG, Buchanan FG, Daikoku T, Holla VR, Rosenberg DW, Dey SK, DuBois RN. Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression. Cancer Research. 66: 6649-56. PMID 16818638 DOI: 10.1158/0008-5472.Can-06-1787 |
0.499 |
|
2006 |
DuBois RN. Cyclooxygenase-2 selective inhibitors and prostate cancer: what is the clinical benefit? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 2691-3. PMID 16782907 DOI: 10.1200/Jco.2006.05.9709 |
0.418 |
|
2006 |
DuBois RN. Cancer prevention: strategy for the future. Carcinogenesis. 27: 1126-7. PMID 16709577 DOI: 10.1093/Carcin/Bgl020 |
0.378 |
|
2006 |
Wang D, Wang H, Brown J, Daikoku T, Ning W, Shi Q, Richmond A, Strieter R, Dey SK, DuBois RN. CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer. The Journal of Experimental Medicine. 203: 941-51. PMID 16567391 DOI: 10.1084/Jem.20052124 |
0.505 |
|
2006 |
Batts LE, Polk DB, Dubois RN, Kulessa H. Bmp signaling is required for intestinal growth and morphogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 1563-70. PMID 16538672 DOI: 10.1002/Dvdy.20741 |
0.36 |
|
2006 |
Buchanan FG, Gorden DL, Matta P, Shi Q, Matrisian LM, DuBois RN. Role of beta-arrestin 1 in the metastatic progression of colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 103: 1492-7. PMID 16432186 DOI: 10.1073/Pnas.0510562103 |
0.415 |
|
2006 |
Buchanan FG, DuBois RN. Connecting COX-2 and Wnt in cancer. Cancer Cell. 9: 6-8. PMID 16413466 DOI: 10.1016/J.Ccr.2005.12.029 |
0.445 |
|
2006 |
Cha YI, Kim SH, Sepich D, Buchanan FG, Solnica-Krezel L, DuBois RN. Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes & Development. 20: 77-86. PMID 16391234 DOI: 10.1101/Gad.1374506 |
0.77 |
|
2006 |
Cha YI, Solnica-Krezel L, DuBois RN. Fishing for prostanoids: deciphering the developmental functions of cyclooxygenase-derived prostaglandins. Developmental Biology. 289: 263-72. PMID 16310177 DOI: 10.1016/J.Ydbio.2005.10.013 |
0.773 |
|
2006 |
Holla VR, Mann JR, Shi Q, DuBois RN. Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer. The Journal of Biological Chemistry. 281: 2676-82. PMID 16293616 DOI: 10.1074/Jbc.M507752200 |
0.476 |
|
2006 |
Wang D, DuBois RN. Prostaglandins And Cancer Gut. 55: 115-122. PMID 16118353 DOI: 10.1136/Gut.2004.047100 |
0.477 |
|
2006 |
Cha YI, DuBois RN. Chemoprevention of colorectal cancer by inhibition of cyclooxygenase-2 derived prostaglandin E2 signaling: Recent advances in basic biology Current Colorectal Cancer Reports. 2: 60-65. DOI: 10.1007/S11888-006-0003-1 |
0.462 |
|
2005 |
Mann JR, Backlund MG, DuBois RN. Mechanisms of disease: Inflammatory mediators and cancer prevention. Nature Clinical Practice. Oncology. 2: 202-10. PMID 16264935 DOI: 10.1038/Ncponc0140 |
0.498 |
|
2005 |
Backlund MG, Mann JR, Dubois RN. Mechanisms for the prevention of gastrointestinal cancer: the role of prostaglandin E2. Oncology. 69: 28-32. PMID 16210874 DOI: 10.1159/000086629 |
0.501 |
|
2005 |
Peek RM, Mohla S, DuBois RN. Inflammation in the genesis and perpetuation of cancer: summary and recommendations from a national cancer institute-sponsored meeting. Cancer Research. 65: 8583-6. PMID 16204020 DOI: 10.1158/0008-5472.Can-05-1777 |
0.414 |
|
2005 |
Musiek ES, Gao L, Milne GL, Han W, Everhart MB, Wang D, Backlund MG, DuBois RN, Zanoni G, Vidari G, Blackwell TS, Morrow JD. Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages. The Journal of Biological Chemistry. 280: 35562-70. PMID 16100121 DOI: 10.1074/Jbc.M504785200 |
0.334 |
|
2005 |
Komatsu K, Buchanan FG, Katkuri S, Morrow JD, Inoue H, Otaka M, Watanabe S, DuBois RN. Oncogenic potential of MEK1 in rat intestinal epithelial cells is mediated via cyclooxygenase-2. Gastroenterology. 129: 577-90. PMID 16083714 DOI: 10.1053/J.Gastro.2005.06.003 |
0.399 |
|
2005 |
Lee SH, Williams MV, Dubois RN, Blair IA. Cyclooxygenase-2-mediated DNA damage. The Journal of Biological Chemistry. 280: 28337-46. PMID 15964853 DOI: 10.1074/Jbc.M504178200 |
0.352 |
|
2005 |
Cha YI, Kim SH, Solnica-Krezel L, Dubois RN. Cyclooxygenase-1 signaling is required for vascular tube formation during development. Developmental Biology. 282: 274-83. PMID 15936346 DOI: 10.1016/J.Ydbio.2005.03.014 |
0.765 |
|
2005 |
Wang D, Mann JR, DuBois RN. The role of prostaglandins and other eicosanoids in the gastrointestinal tract. Gastroenterology. 128: 1445-61. PMID 15887126 DOI: 10.1053/J.Gastro.2004.09.080 |
0.407 |
|
2005 |
Daikoku T, Wang D, Tranguch S, Morrow JD, Orsulic S, DuBois RN, Dey SK. Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer. Cancer Research. 65: 3735-44. PMID 15867369 DOI: 10.1158/0008-5472.Can-04-3814 |
0.489 |
|
2005 |
Brown JR, DuBois RN. COX-2: a molecular target for colorectal cancer prevention. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 2840-55. PMID 15837998 DOI: 10.1200/Jco.2005.09.051 |
0.463 |
|
2005 |
Wang D, Buchanan FG, Wang H, Dey SK, DuBois RN. Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade. Cancer Research. 65: 1822-9. PMID 15753380 DOI: 10.1158/0008-5472.Can-04-3671 |
0.447 |
|
2005 |
Buchanan FG, McReynolds M, Couvillon A, Kam Y, Holla VR, DuBois RN, Exton JH. Requirement of phospholipase D1 activity in H-RasV12-induced transformation Proceedings of the National Academy of Sciences of the United States of America. 102: 1638-1642. PMID 15668389 DOI: 10.1073/Pnas.0406698102 |
0.312 |
|
2005 |
Backlund MG, Mann JR, Holla VR, Buchanan FG, Tai HH, Musiek ES, Milne GL, Katkuri S, DuBois RN. 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. The Journal of Biological Chemistry. 280: 3217-23. PMID 15542609 DOI: 10.1074/Jbc.M411221200 |
0.442 |
|
2005 |
Holla VR, Wang D, Brown JR, Mann JR, Katkuri S, DuBois RN. Prostaglandin E2 regulates the complement inhibitor CD55/decay-accelerating factor in colorectal cancer. The Journal of Biological Chemistry. 280: 476-83. PMID 15520008 DOI: 10.1074/Jbc.M407403200 |
0.516 |
|
2004 |
Wang D, Mann JR, DuBois RN. WNT and cyclooxygenase-2 cross-talk accelerates adenoma growth. Cell Cycle (Georgetown, Tex.). 3: 1512-5. PMID 15539957 DOI: 10.4161/cc.3.12.1288 |
0.355 |
|
2004 |
Buchanan FG, Chang W, Sheng H, Shao J, Morrow JD, DuBois RN. Up-regulation of the enzymes involved in prostacyclin synthesis via Ras induces vascular endothelial growth factor. Gastroenterology. 127: 1391-400. PMID 15521009 DOI: 10.1053/J.Gastro.2004.07.025 |
0.376 |
|
2004 |
Wang D, Wang H, Shi Q, Katkuri S, Walhi W, Desvergne B, Das SK, Dey SK, DuBois RN. Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell. 6: 285-95. PMID 15380519 DOI: 10.1016/J.Ccr.2004.08.011 |
0.465 |
|
2004 |
Mann JR, DuBois RN. Cyclooxygenase-2 and gastrointestinal cancer. Cancer Journal (Sudbury, Mass.). 10: 145-52. PMID 15285921 DOI: 10.1097/00130404-200405000-00001 |
0.478 |
|
2004 |
Koehne CH, Dubois RN. COX-2 inhibition and colorectal cancer. Seminars in Oncology. 31: 12-21. PMID 15252926 DOI: 10.1053/J.Seminoncol.2004.03.041 |
0.45 |
|
2004 |
Brown JR, DuBois RN. Cyclooxygenase as a target in lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4266s-4269s. PMID 15217972 DOI: 10.1158/1078-0432.Ccr-040014 |
0.406 |
|
2004 |
Lynch TJ, Adjei AA, Bunn PA, DuBois RN, Gandara DR, Giaccone G, Govindan R, Herbst RS, Johnson BE, Khuri FR, Perez-Soler R, Rosell R, Rowinsky EK, Sandler AB, Scagliotti GV, et al. Novel agents in the treatment of lung cancer: conference summary statement. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4199s-4204s. PMID 15217958 DOI: 10.1158/1078-0432.Ccr-040021 |
0.325 |
|
2004 |
Yoshinaga M, Buchanan FG, DuBois RN. 15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells. Prostaglandins & Other Lipid Mediators. 73: 111-22. PMID 15165036 DOI: 10.1016/S0016-5085(03)82343-0 |
0.419 |
|
2004 |
Wang D, Dubois RN. Cyclooxygenase-2: a potential target in breast cancer. Seminars in Oncology. 31: 64-73. PMID 15052544 DOI: 10.1053/J.Seminoncol.2004.01.008 |
0.415 |
|
2004 |
Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, DuBois RN. Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nature Medicine. 10: 245-7. PMID 14758356 DOI: 10.1038/Nm993 |
0.644 |
|
2004 |
Wang D, DuBois RN. Cyclooxygenase 2-derived prostaglandin E2 regulates the angiogenic switch. Proceedings of the National Academy of Sciences of the United States of America. 101: 415-6. PMID 14707264 DOI: 10.1073/Pnas.0307640100 |
0.433 |
|
2004 |
Mann JR, DuBois RN. Cancer chemoprevention: myth or reality? Drug Discovery Today: Therapeutic Strategies. 1: 403-409. DOI: 10.1016/J.Ddstr.2004.10.003 |
0.386 |
|
2003 |
Herschman HR, Talley JJ, DuBois R. Cyclooxygenase 2 (COX-2) as a target for therapy and noninvasive imaging. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 5: 286-303. PMID 14630509 DOI: 10.1016/J.Mibio.2003.09.006 |
0.347 |
|
2003 |
Crosby CG, DuBois RN. The cyclooxygenase-2 pathway as a target for treatment or prevention of cancer. Expert Opinion On Emerging Drugs. 8: 1-7. PMID 14610907 DOI: 10.1517/14728214.8.1.1 |
0.366 |
|
2003 |
DuBois RN. Leukotriene A4 Signaling, Inflammation, and Cancer Journal of the National Cancer Institute. 95: 1028-1029. PMID 12865441 DOI: 10.1093/Jnci/95.14.1028 |
0.449 |
|
2003 |
Buchanan FG, Wang D, Bargiacchi F, DuBois RN. Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. Journal of Biological Chemistry. 278: 35451-35457. PMID 12824187 DOI: 10.1074/Jbc.M302474200 |
0.404 |
|
2003 |
DuBois RN. Cyclooxygenase-2 and colorectal cancer. Progress in Experimental Tumor Research. 37: 124-137. PMID 12795052 DOI: 10.1159/000071370 |
0.4 |
|
2003 |
Wagenaar-Miller RA, Hanley G, Shattuck-Brandt R, DuBois RN, Bell RL, Matrisian LM, Morgan DW. Cooperative effects of matrix metalloproteinase and cyclooxygenase-2 inhibition on intestinal adenoma reduction. British Journal of Cancer. 88: 1445-52. PMID 12778076 DOI: 10.1038/Sj.Bjc.6600867 |
0.394 |
|
2003 |
Gupta RA, Tejada LV, Tong BJ, Das SK, Morrow JD, Dey SK, DuBois RN. Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer. Cancer Research. 63: 906-11. PMID 12615701 |
0.682 |
|
2003 |
Gupta RA, Sarraf P, Mueller E, Brockman JA, Prusakiewicz JJ, Eng C, Willson TM, DuBois RN. Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms. The Journal of Biological Chemistry. 278: 22669-77. PMID 12591919 DOI: 10.1074/Jbc.M300637200 |
0.694 |
|
2003 |
Daikoku T, Matsumoto H, Gupta RA, Das SK, Gassmann M, DuBois RN, Dey SK. Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner. Evidence for differential function of HIFs during early pregnancy. The Journal of Biological Chemistry. 278: 7683-91. PMID 12482866 DOI: 10.1074/Jbc.M211390200 |
0.637 |
|
2003 |
Gupta RA, Sarraf P, Brockman JA, Shappell SB, Raftery LA, Willson TM, DuBois RN. Peroxisome proliferator-activated receptor gamma and transforming growth factor-beta pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22. The Journal of Biological Chemistry. 278: 7431-8. PMID 12468551 DOI: 10.1074/Jbc.M208076200 |
0.634 |
|
2003 |
Komatsu K, Bose B, Morrow JD, Inoue H, Dubois RN. Constitutively activated MEK1 represses sodium butyrate induced cell differentiation and apoptosis in rat intestinal epithelial cells Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)83032-9 |
0.333 |
|
2003 |
Shao J, Sheng H, Dubois RN. Prostaglandin E2 stimulates colon cancer cell growth through induction of amphiregulin Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81426-9 |
0.412 |
|
2002 |
Gupta RA, DuBois RN, Wallace MC. New avenues for the prevention of colorectal cancer: targeting cyclo-oxygenase-2 activity. Best Practice & Research. Clinical Gastroenterology. 16: 945-56. PMID 12473300 DOI: 10.1053/Bega.2002.0353 |
0.709 |
|
2002 |
DuBois RN. New Agents for Cancer Prevention Journal of the National Cancer Institute. 94: 1732-1733. PMID 12464639 DOI: 10.1093/Jnci/94.23.1732 |
0.353 |
|
2002 |
Turini ME, DuBois RN. Primary prevention: phytoprevention and chemoprevention of colorectal cancer. Hematology-Oncology Clinics of North America. 16: 811-840. PMID 12418050 DOI: 10.1016/S0889-8588(02)00030-8 |
0.382 |
|
2002 |
Gupta RA, Dubois RN. Controversy: PPARgamma as a target for treatment of colorectal cancer. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G266-9. PMID 12121872 DOI: 10.1152/Ajpgi.00486.2001 |
0.694 |
|
2002 |
Hawk ET, Viner JL, Dannenberg A, DuBois RN. COX-2 in cancer--a player that's defining the rules. Journal of the National Cancer Institute. 94: 545-6. PMID 11959883 DOI: 10.1093/Jnci/94.8.545 |
0.364 |
|
2002 |
Kozak KR, Gupta RA, Moody JS, Ji C, Boeglin WE, DuBois RN, Brash AR, Marnett LJ. 15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist. The Journal of Biological Chemistry. 277: 23278-86. PMID 11956198 DOI: 10.1074/Jbc.M201084200 |
0.622 |
|
2002 |
Gupta RA, DuBois RN. Cyclooxygenase-2 inhibitor therapy for the prevention of esophageal adenocarcinoma in Barrett's esophagus. Journal of the National Cancer Institute. 94: 406-7. PMID 11904306 DOI: 10.1093/Jnci/94.6.406 |
0.721 |
|
2002 |
Kawai N, Tsuji S, Tsujii M, Ito T, Yasumaru M, Kakiuchi Y, Kimura A, Komori M, Sasaki Y, Hayashi N, Kawano S, Dubois R, Hori M. Tumor necrosis factor α stimulates invasion of Src-activated intestinal cells Gastroenterology. 122: 331-339. PMID 11832448 DOI: 10.1053/Gast.2002.31023 |
0.382 |
|
2002 |
Turini ME, DuBois RN. Cyclooxygenase-2: a therapeutic target. Annual Review of Medicine. 53: 35-57. PMID 11818462 DOI: 10.1146/Annurev.Med.53.082901.103952 |
0.391 |
|
2002 |
Marnett LJ, DuBois RN. COX-2: a target for colon cancer prevention. Annual Review of Pharmacology and Toxicology. 42: 55-80. PMID 11807164 DOI: 10.1146/Annurev.Pharmtox.42.082301.164620 |
0.374 |
|
2001 |
Kandil HM, DuBois RN. Cclooxygenase-2 (COX-2) Protein Expression by Western Blotting Methods in Molecular Medicine. 50: 205-211. PMID 21318829 DOI: 10.1385/1-59259-084-5:205 |
0.415 |
|
2001 |
DuBois RN. Nonsteroidal antiinflammatory drugs, cyclooxygenase-2, and colorectal cancer prevention. Current Opinion in Gastroenterology. 17: 65-71. PMID 17031153 DOI: 10.1097/00001574-200101000-00013 |
0.449 |
|
2001 |
Krause WF, DuBois RN. The Molecular Basis for Prevention of Colorectal Cancer Clinical Colorectal Cancer. 1: 47-54. PMID 12445379 DOI: 10.3816/Ccc.2001.N.005 |
0.448 |
|
2001 |
Gupta RA, Dubois RN. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nature Reviews. Cancer. 1: 11-21. PMID 11900248 DOI: 10.1038/35094017 |
0.711 |
|
2001 |
Stack E, DuBois RN. Role Of Cyclooxygenase Inhibitors For The Prevention Of Colorectal Cancer Gastroenterology Clinics of North America. 30: 1001-1010. PMID 11764529 DOI: 10.1016/S0889-8553(05)70225-9 |
0.491 |
|
2001 |
Williams CS, Sheng H, Brockman JA, Armandla R, Shao J, Washington MK, Elkahloun AG, Dubois RN. A Cyclooxygenase-2 Inhibitor (SC-58125) Blocks Growth of Established Human Colon Cancer Xenografts Neoplasia. 3: 428-436. PMID 11687954 DOI: 10.1038/Sj.Neo.7900177 |
0.592 |
|
2001 |
Stack E, DuBois RN. Regulation of cyclo-oxygenase-2. Best Practice & Research in Clinical Gastroenterology. 15: 787-800. PMID 11566041 DOI: 10.1053/Bega.2001.0235 |
0.361 |
|
2001 |
Kobayashi O, Miwa H, Watanabe S, Tsujii M, Dubois RN, Sato N. Cyclooxygenase-2 downregulates inducible nitric oxide synthase in rat intestinal epithelial cells American Journal of Physiology-Gastrointestinal and Liver Physiology. 281. PMID 11518681 DOI: 10.1152/Ajpgi.2001.281.3.G688 |
0.325 |
|
2001 |
Zhang Z, DuBois RN. Detection of differentially expressed genes in human colon carcinoma cells treated with a selective COX-2 inhibitor Oncogene. 20: 4450-4456. PMID 11494140 DOI: 10.1038/Sj.Onc.1204588 |
0.403 |
|
2001 |
Gupta RA, Polk DB, Krishna U, Israel DA, Yan F, DuBois RN, Peek RM. Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kappa B-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells. The Journal of Biological Chemistry. 276: 31059-66. PMID 11397815 DOI: 10.1074/Jbc.M104141200 |
0.656 |
|
2001 |
Gupta RA, Brockman JA, Sarraf P, Willson TM, DuBois RN. Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells. The Journal of Biological Chemistry. 276: 29681-7. PMID 11397807 DOI: 10.1074/Jbc.M103779200 |
0.653 |
|
2001 |
Mann M, Sheng H, Shao J, Williams CS, Dubois RN, Pisacane PI, Sliwkowski MX. Targeting cyclooxygenase 2 and HER-2/neu pathways inhibits colorectal carcinoma growth. Gastroenterology. 120: 1713-1719. PMID 11375952 DOI: 10.1053/Gast.2001.24844 |
0.59 |
|
2001 |
Kandil HM, Tanner G, Smalley W, Halter S, Radhika A, Dubois RN. Cyclooxygenase-2 expression in Barrett's esophagus. Digestive Diseases and Sciences. 46: 785-789. PMID 11330414 DOI: 10.1023/A:1010700400960 |
0.332 |
|
2001 |
DuBois RN. New paradigms for cancer prevention. Carcinogenesis. 22: 691-692. PMID 11323385 DOI: 10.1093/Carcin/22.5.691 |
0.477 |
|
2001 |
Souto EO, Miyoshi H, Dubois RN, Gores GJ. Kupffer cell-derived cyclooxygenase-2 regulates hepatocyte Bcl-2 expression in choledocho-venous fistula rats. American Journal of Physiology-Gastrointestinal and Liver Physiology. 280. PMID 11292587 DOI: 10.1152/Ajpgi.2001.280.5.G805 |
0.344 |
|
2001 |
Sheng H, Shao J, DuBois RN. Akt/PKB Activity Is Required for Ha-Ras-mediated Transformation of Intestinal Epithelial Cells Journal of Biological Chemistry. 276: 14498-14504. PMID 11278613 DOI: 10.1074/Jbc.M010093200 |
0.333 |
|
2001 |
Sheng H, Shao J, Washington MK, DuBois RN. Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. Journal of Biological Chemistry. 276: 18075-18081. PMID 11278548 DOI: 10.1074/Jbc.M009689200 |
0.469 |
|
2001 |
Shappell SB, Gupta RA, Manning S, Whitehead R, Boeglin WE, Schneider C, Case T, Price J, Jack GS, Wheeler TM, Matusik RJ, Brash AR, Dubois RN. 15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells. Cancer Research. 61: 497-503. PMID 11212240 |
0.609 |
|
2001 |
Yang VW, DuBois RN. The molecular medicine of colorectal cancer Trends in Molecular Medicine. 7: 241-242. DOI: 10.1016/S1471-4914(01)02036-6 |
0.377 |
|
2001 |
Kakiuchi Y, Tsuji S, Tsujii M, Kawai N, Yasumaru M, Kimura A, Komori M, Sasaki Y, Dubois RN, Hori M, Kawano S. COX-2 increases adhesion of human colon carcinoma cells—Possible role of NSAIDs in suppression of liver metastasis Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)82958-7 |
0.313 |
|
2001 |
Tsujii M, Tsuji S, Kawai N, Yasumaru M, Kakiuchi Y, Kimura A, Komori M, Sasaki Y, Dubois RN, Hori M. Combinatorial chemoprevention using NSAIDs, COX-2 inhibitors and antioxidants μμ Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)82955-1 |
0.312 |
|
2001 |
Sheng H, Shao J, Dubois RN. Prostaglandin E2 increases growth and invesiveness of colorectal carcinoma cells Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)82451-1 |
0.342 |
|
2000 |
Zhang Z, Sheng H, Shao J, Beauchamp RD, DuBois RN. Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells. Neoplasia (New York, N.Y.). 2: 523-30. PMID 11228545 DOI: 10.1038/Sj.Neo.7900117 |
0.327 |
|
2000 |
Tong BJ, Tan J, Tajeda L, Das SK, Chapman JA, DuBois RN, Dey SK. Heightened expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-delta in human endometrial adenocarcinoma. Neoplasia (New York, N.Y.). 2: 483-90. PMID 11228540 DOI: 10.1038/Sj.Neo.7900119 |
0.484 |
|
2000 |
Gupta RA, Tan J, Krause WF, Geraci MW, Willson TM, Dey SK, DuBois RN. Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 97: 13275-80. PMID 11087869 DOI: 10.1073/Pnas.97.24.13275 |
0.729 |
|
2000 |
Arber N, DuBois RN. Nonsteroidal anti-inflammatory drugs and prevention of colorectal cancer. Current Gastroenterology Reports. 1: 441-8. PMID 10980984 DOI: 10.1007/S11894-999-0027-1 |
0.434 |
|
2000 |
Gupta RA, DuBois RN. Combinations for cancer prevention. Nature Medicine. 6: 974-5. PMID 10973312 DOI: 10.1038/79664 |
0.676 |
|
2000 |
Shao J, Sheng H, Inoue H, Morrow JD, DuBois RN. Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. Journal of Biological Chemistry. 275: 33951-33956. PMID 10930401 DOI: 10.1074/Jbc.M002324200 |
0.413 |
|
2000 |
Callejas NA, Boscá L, Williams CS, DuBois RN, Martín-Sanz P. Regulation of cyclooxygenase 2 expression in hepatocytes by CCAAT/enhancer-binding proteins Gastroenterology. 119: 493-501. PMID 10930384 DOI: 10.1053/Gast.2000.9374 |
0.496 |
|
2000 |
Gupta RA, DuBois RN. Translational studies on Cox-2 inhibitors in the prevention and treatment of colon cancer. Annals of the New York Academy of Sciences. 910: 196-204; discussion . PMID 10911914 DOI: 10.1111/J.1749-6632.2000.Tb06709.X |
0.709 |
|
2000 |
Steinbach G, Lynch PM, Phillips RK, Wallace MH, Hawk E, Gordon GB, Wakabayashi N, Saunders B, Shen Y, Fujimura T, Su LK, Levin B, Godio L, Patterson S, Rodriguez-Bigas MA, ... ... DuBois RN, et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. The New England Journal of Medicine. 342: 1946-52. PMID 10874062 DOI: 10.1056/Nejm200006293422603 |
0.304 |
|
2000 |
Krause W, DuBois RN. Eicosanoids and the large intestine. Prostaglandins & Other Lipid Mediators. 61: 145-161. PMID 10867126 DOI: 10.1016/S0090-6980(00)00069-1 |
0.35 |
|
2000 |
Williams CS, Tsujii M, Reese J, Dey SK, DuBois RN. Host cyclooxygenase-2 modulates carcinoma growth. The Journal of Clinical Investigation. 105: 1589-94. PMID 10841517 DOI: 10.1172/Jci9621 |
0.535 |
|
2000 |
Zhang Z, DuBois RN. Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells. Gastroenterology. 118: 1012-7. PMID 10833474 DOI: 10.1016/S0016-5085(00)70352-0 |
0.382 |
|
2000 |
Shao J, Sheng H, DuBois RN, Beauchamp RD. Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation. The Journal of Biological Chemistry. 275: 22916-24. PMID 10781597 DOI: 10.1074/Jbc.M002235200 |
0.345 |
|
2000 |
Lipsky PE, Brooks P, Crofford LJ, DuBois R, Graham D, Simon LS, van de Putte LB, Abramson SB. Unresolved issues in the role of cyclooxygenase-2 in normal physiologic processes and disease. Archives of Internal Medicine. 160: 913-20. PMID 10761955 DOI: 10.1001/Archinte.160.7.913 |
0.355 |
|
2000 |
Sheng H, Shao J, Dixon DA, Williams CS, Prescott SM, DuBois RN, Beauchamp RD. Transforming growth factor-beta1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA. The Journal of Biological Chemistry. 275: 6628-35. PMID 10692471 DOI: 10.1074/Jbc.275.9.6628 |
0.48 |
|
2000 |
Shattuck-Brandt RL, Varilek GW, Radhika A, Yang F, Washington MK, DuBois RN. Cyclooxygenase 2 expression is increased in the stroma of colon carcinomas from IL–10−/− mice Gastroenterology. 118: 337-345. PMID 10648462 DOI: 10.1016/S0016-5085(00)70216-2 |
0.373 |
|
2000 |
Gupta RA, Radhika A, Shao J, Sheng H, Dey SK, DuBois RN. PparΔ is a putative downstream receptor of COX-2 derived prostacyclin during colorectal carcinogenesis Gastroenterology. 118: A681. DOI: 10.1016/S0016-5085(00)84861-1 |
0.65 |
|
2000 |
Zhang Z, DuBois RN. Detection of differentially expressed genes following NSAID treatment of colorectal cancer cells Gastroenterology. 118: 286-287. DOI: 10.1016/S0016-5085(00)83230-8 |
0.399 |
|
2000 |
Peek RM, Gupta RA, Krishna US, DuBois RN. Helicobacter pylori cagA+ strain-induced apoptosis is attenuated by activation of PPAR-Γ Gastroenterology. 118: A172. DOI: 10.1016/S0016-5085(00)82767-5 |
0.596 |
|
2000 |
Sheng H, Shao J, Helou RA, Williams CN, DuBois RN. Selective inhibition of colon carcinoma xenografts by celecoxib Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)82296-9 |
0.309 |
|
2000 |
Krause WF, Gupta RA, DuBois RN. Characterization of the PPAR-Δ activation function-2 domain Gastroenterology. 118: A54-A55. DOI: 10.1016/S0016-5085(00)82288-X |
0.579 |
|
1999 |
Shattuck-Brandt RL, DuBois RN. The molecular basis of colorectal carcinogenesis. Current Opinion in Gastroenterology. 15: 3-8. PMID 17023910 DOI: 10.1097/00001574-199901000-00002 |
0.334 |
|
1999 |
Williams CS, Shattuck-Brandt RL, DuBois RN. The role of COX-2 in intestinal cancer. Expert Opinion On Investigational Drugs. 8: 1-12. PMID 15992053 DOI: 10.1517/13543784.8.1.1 |
0.609 |
|
1999 |
Williams CS, Goldman AP, Sheng H, Morrow JD, DuBois RN. Sulindac Sulfide, but Not Sulindac Sulfone, Inhibits Colorectal Cancer Growth Neoplasia. 1: 170-176. PMID 10933052 DOI: 10.1038/Sj.Neo.7900024 |
0.595 |
|
1999 |
Williams C, Shattuck-Brandt RL, DuBOIS RN. The Role of COX‐2 in Intestinal Cancer Annals of the New York Academy of Sciences. 889: 72-83. PMID 10668484 DOI: 10.1111/J.1749-6632.1999.Tb08725.X |
0.616 |
|
1999 |
Williams CS, Mann M, DuBois RN. The role of cyclooxygenases in inflammation, cancer, and development Oncogene. 18: 7908-7916. PMID 10630643 DOI: 10.1038/Sj.Onc.1203286 |
0.595 |
|
1999 |
Watson A, DuBOIS RN. Cryptic messages in FAP Gut. 45: 795-796. PMID 10562573 DOI: 10.1136/Gut.45.6.795 |
0.468 |
|
1999 |
DuBOIS RN. COX-2 in large bowel cancer: a one-sided story Gut. 45: 636-637. PMID 10517891 DOI: 10.1136/Gut.45.5.636 |
0.359 |
|
1999 |
Lim H, Gupta RA, Ma WG, Paria BC, Moller DE, Morrow JD, DuBois RN, Trzaskos JM, Dey SK. Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. Genes & Development. 13: 1561-74. PMID 10385625 DOI: 10.1101/Gad.13.12.1561 |
0.639 |
|
1999 |
Shattuck-Brandt RL, Lamps LW, Heppner Goss KJ, DuBois RN, Matrisian LM. Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms. Molecular Carcinogenesis. 24: 177-87. PMID 10204802 DOI: 10.1002/(Sici)1098-2744(199903)24:3<177::Aid-Mc4>3.0.Co;2-6 |
0.431 |
|
1999 |
Shao J, Sheng H, Aramandla R, Pereira MA, Lubet RA, Hawk E, Grogan L, Kirsch IR, Washington MK, Beauchamp RD, DuBois RN. Coordinate regulation of cyclooxygenase-2 and TGF-beta1 in replication error-positive colon cancer and azoxymethane-induced rat colonic tumors. Carcinogenesis. 20: 185-91. PMID 10069452 DOI: 10.1093/Carcin/20.2.185 |
0.426 |
|
1999 |
Sheng H, Shao J, O'Mahony CA, Lamps L, Albo D, Isakson PC, Berger DH, DuBois RN, Beauchamp RD. Transformation of intestinal epithelial cells by chronic TGF-beta1 treatment results in downregulation of the type II TGF-beta receptor and induction of cyclooxygenase-2. Oncogene. 18: 855-67. PMID 10023661 DOI: 10.1038/Sj.Onc.1202397 |
0.336 |
|
1999 |
DuBois RN. Cyclooxygenase and cancer Prostaglandins & Other Lipid Mediators. 59: 59. DOI: 10.1016/S0090-6980(99)90294-0 |
0.391 |
|
1999 |
O'Mahony CA, Beauchamp RD, Albo D, Tsujii M, Sheng HM, Shao J, Dubois RN, Berger DH. Cyclooxygenase-2 alters transforming growth factor-β1 response during intestinal tumorigenesis Surgery. 126: 364-370. DOI: 10.1016/S0039-6060(99)70178-9 |
0.32 |
|
1998 |
Goldman AP, Williams CS, Sheng H, Lamps LW, Williams VP, Pairet M, D.morrow J, DuBois RN. Meloxicam inhibits the growth of colorectal cancer cells Carcinogenesis. 19: 2195-2199. PMID 9886578 DOI: 10.1093/Carcin/19.12.2195 |
0.583 |
|
1998 |
Brockman JA, Gupta RA, Dubois RN. Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology. 115: 1049-55. PMID 9797355 DOI: 10.1016/S0016-5085(98)70072-1 |
0.692 |
|
1998 |
Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van De Putte LB, Lipsky PE. Cyclooxygenase in biology and disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1063-73. PMID 9737710 DOI: 10.1096/Fasebj.12.12.1063 |
0.665 |
|
1998 |
Sheng H, Williams CS, Shao J, Liang P, DuBois RN, Beauchamp RD. Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. The Journal of Biological Chemistry. 273: 22120-7. PMID 9705357 DOI: 10.1074/Jbc.273.34.22120 |
0.526 |
|
1998 |
Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, DuBois RN. Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells Cell. 93: 705-716. PMID 9630216 DOI: 10.1016/S0092-8674(00)81433-6 |
0.435 |
|
1998 |
Gupta RA, DuBois RN. Aspirin, NSAIDS, and colon cancer prevention: mechanisms? Gastroenterology. 114: 1095-8. PMID 9606094 DOI: 10.1016/S0016-5085(98)70330-0 |
0.682 |
|
1998 |
Sheng H, Shao J, Williams CS, Pereira MA, Taketo MM, Oshima M, Reynolds AB, Washington MK, DuBois RN, Beauchamp RD. Nuclear translocation of beta-catenin in hereditary and carcinogen-induced intestinal adenomas. Carcinogenesis. 19: 543-9. PMID 9600336 DOI: 10.1093/Carcin/19.4.543 |
0.495 |
|
1998 |
Giardiello FM, Spannhake EW, Dubois RN, Hylind LM, Robinson CR, Hubbard WC, Hamilton SR, Yang VW. Prostaglandin levels in human colorectal mucosa: Effects of sulindac in patients with familial adenomatous polyposis Digestive Diseases and Sciences. 43: 311-316. PMID 9512123 DOI: 10.1023/A:1018898120673 |
0.358 |
|
1998 |
DuBois RN, Gupta R, Brockman J, Reddy BS, Krakow SL, Lazar MA. The nuclear eicosanoid receptor, PPARγ, is aberrantly expressed in colonic cancers Carcinogenesis. 19: 49-53. PMID 9472692 DOI: 10.1093/Carcin/19.1.49 |
0.484 |
|
1998 |
Tsujii M, Kawano S, Tsuji S, Takei Y, Nagai H, Sawaoka H, Murata H, Kawai N, Hori M, DuBois RN. Effect of cyclooxygenase-2 expression in colon cancer cells on chemotaxis of neutrophils and macrophages Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)82846-1 |
0.437 |
|
1998 |
Gupta R, Brockman J, DuBois R. Assessment of PPARα activity in the intestine Gastroenterology. 114: A604. DOI: 10.1016/S0016-5085(98)82467-0 |
0.605 |
|
1998 |
Goldman A, Williams C, Williams V, DuBois R. Colon cancer cell growth inhibition by treatment with a selective cox-2 inhibitor Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)82453-0 |
0.585 |
|
1997 |
Dubois R, Tsujii M, Morrow J, Awad J, Roberts L, Bishop P. Eicosanoid Production and Growth Regulation in Rat Intestinal Epithelial Cells Advances in Experimental Medicine and Biology. 487-93. PMID 9547594 DOI: 10.1007/978-1-4615-5325-0_65 |
0.471 |
|
1997 |
Sheng GG, Shao J, Sheng H, Hooton EB, Isakson PC, Morrow JD, Coffey RJ, DuBois RN, Beauchamp RD. A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal epithelial cells. Gastroenterology. 113: 1883-91. PMID 9394727 DOI: 10.1016/S0016-5085(97)70007-6 |
0.377 |
|
1997 |
Williams CS, Smalley W, DuBois RN. Aspirin use and potential mechanisms for colorectal cancer prevention. Journal of Clinical Investigation. 100: 1325-1329. PMID 9294096 DOI: 10.1172/Jci119651 |
0.541 |
|
1997 |
Guan Y, Chang M, Cho W, Zhang Y, Redha R, Davis L, Chang S, DuBois RN, Hao CM, Breyer M. Cloning, expression, and regulation of rabbit cyclooxygenase-2 in renal medullary interstitial cells. The American Journal of Physiology. 273: F18-26. PMID 9249588 DOI: 10.1152/Ajprenal.1997.273.1.F18 |
0.365 |
|
1997 |
Smalley WE, DuBois RN. Colorectal Cancer and Nonsteroidal Anti-inflammatory Drugs Advances in Pharmacology (San Diego). 39: 1-20. PMID 9160111 DOI: 10.1016/S1054-3589(08)60067-8 |
0.457 |
|
1997 |
Sheng H, Shao J, Kirkland SC, Isakson P, Coffey RJ, Morrow J, Beauchamp RD, DuBois RN. Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. The Journal of Clinical Investigation. 99: 2254-9. PMID 9151799 DOI: 10.1172/Jci119400 |
0.496 |
|
1997 |
Tsujii M, Kawano S, DuBois RN. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential Proceedings of the National Academy of Sciences of the United States of America. 94: 3336-3340. PMID 9096394 DOI: 10.1073/Pnas.94.7.3336 |
0.474 |
|
1997 |
Watson AJ, DuBois RN. Lipid metabolism and APC: implications for colorectal cancer prevention. The Lancet. 349: 444-445. PMID 9040567 DOI: 10.1016/S0140-6736(97)22007-6 |
0.355 |
|
1997 |
DuBois RN, Smalley WE. Cyclooxygenase, NSAIDs, and colorectal cancer. Journal of Gastroenterology. 31: 898-906. PMID 9027660 DOI: 10.1007/Bf02358623 |
0.428 |
|
1997 |
Coffey RJ, Hawkey CJ, Damstrup L, Graves-Deal R, Daniel VC, Dempsey PJ, Chinery R, Kirkland SC, DuBois RN, Jetton TL, Morrow JD. Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells Proceedings of the National Academy of Sciences of the United States of America. 94: 657-662. PMID 9012840 DOI: 10.1073/Pnas.94.2.657 |
0.426 |
|
1997 |
Schmedtje JF, Ji YS, Liu WL, DuBois RN, Runge MS. Hypoxia Induces Cyclooxygenase-2 via the NF-κB p65 Transcription Factor in Human Vascular Endothelial Cells Journal of Biological Chemistry. 272: 601-608. PMID 8995303 DOI: 10.1074/Jbc.272.1.601 |
0.331 |
|
1996 |
DuBois RN, Eberhart CE, Williams CS. Introduction to eicosanoids and the gastroenteric tract. Gastroenterology Clinics of North America. 25: 267-277. PMID 9229572 DOI: 10.1016/S0889-8553(05)70246-6 |
0.582 |
|
1996 |
DuBois RN, Giardiello FM, Smalley WE. Nonsteroidal Anti-Inflammatory Drugs, Eicosanoids, And Colorectal Cancer Prevention Gastroenterology Clinics of North America. 25: 773-791. PMID 8960892 DOI: 10.1016/S0889-8553(05)70274-0 |
0.48 |
|
1996 |
Williams CS, Luongo C, Radhika A, Zhang T, Lamps LW, Nanney LB, Beauchamp RD, DuBois RN. Elevated cyclooxygenase-2 levels in Min mouse adenomas. Gastroenterology. 111: 1134-40. PMID 8831610 DOI: 10.1016/S0016-5085(96)70083-5 |
0.53 |
|
1996 |
Williams CS, DuBois RN. Prostaglandin endoperoxide synthase: why two isoforms? American Journal of Physiology-Gastrointestinal and Liver Physiology. 270. PMID 8638704 DOI: 10.1152/Ajpgi.1996.270.3.G393 |
0.461 |
|
1996 |
DuBois RN, Radhika A, Reddy BS, Entingh AJ. Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterology. 110: 1259-62. PMID 8613017 DOI: 10.1053/Gast.1996.V110.Pm8613017 |
0.409 |
|
1996 |
Beauchamp DR, Peeler MO, DuBois RN. recent advances in the management of colorectal polyps Current Opinion in Gastroenterology. 12: 12-17. DOI: 10.1097/00001574-199601000-00004 |
0.318 |
|
1995 |
Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2 Cell. 83: 493-501. PMID 8521479 DOI: 10.1016/0092-8674(95)90127-2 |
0.397 |
|
1995 |
Capdevila JH, Morrow JD, Belosludtsev YY, Beauchamp DR, DuBois RN, Falck JR. The catalytic outcomes of the constitutive and the mitogen inducible isoforms of prostaglandin H2 synthase are markedly affected by glutathione and glutathione peroxidase(s). Biochemistry. 34: 3325-37. PMID 7880828 DOI: 10.1021/Bi00010A023 |
0.314 |
|
1995 |
DuBois RN. Nonsteroidal anti-inflammatory drug use and sporadic colorectal adenomas. Gastroenterology. 108: 1310-1314. PMID 7698600 DOI: 10.1016/0016-5085(95)90235-X |
0.375 |
|
1995 |
Giardiello FM, Offerhaus GJA, DuBois RN. The Role of Nonsteroidal Anti-inflammatory Drugs in Colorectal Cancer Prevention European Journal of Cancer. 31: 1071-1076. PMID 7576994 DOI: 10.1016/0959-8049(95)00137-8 |
0.413 |
|
1994 |
DuBois RN, Tsujii M, Bishop P, Awad JA, Makita K, Lanahan A. Cloning and characterization of a growth factor-inducible cyclooxygenase gene from rat intestinal epithelial cells American Journal of Physiology-Gastrointestinal and Liver Physiology. 266. PMID 8203528 DOI: 10.1152/Ajpgi.1994.266.5.G822 |
0.335 |
|
1994 |
Dubois RN. Activin A and hepatocyte growth regulation Hepatology. 19: 788-790. PMID 8119708 DOI: 10.1002/Hep.1840190336 |
0.302 |
|
1994 |
DuBois RN, Awad J, Morrow J, Roberts LJ, Bishop PR. Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester. Journal of Clinical Investigation. 93: 493-498. PMID 8113389 DOI: 10.1172/Jci116998 |
0.349 |
|
1994 |
Harris RC, McKanna JA, Akai Y, Jacobson HR, Dubois RN, Breyer MD. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. The Journal of Clinical Investigation. 94: 2504-10. PMID 7989609 DOI: 10.1172/Jci117620 |
0.322 |
|
1994 |
Eberhart CE, Coffey RJ, Radhika A, Giardiello FM, Ferrenbach S, Dubois RN. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology. 107: 1183-1188. PMID 7926468 DOI: 10.1016/0016-5085(94)90246-1 |
0.443 |
|
1994 |
DuBois RN. Can we prevent colorectal cancer Digestive Diseases. 12: 255-258. PMID 7882546 DOI: 10.1159/000171460 |
0.398 |
|
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