Margaret M. Chou - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Pharmacology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jain K, Henrich IC, Quick L, Young R, Mondal S, Oliveira AM, Blobel GA, Chou MM. Natural Killer Cell Activation by Ubiquitin-specific Protease 6 Mediates Tumor Suppression in Ewing Sarcoma. Cancer Research Communications. 3: 1615-1627. PMID 37615015 DOI: 10.1158/2767-9764.CRC-22-0505  0.794
2022 Deng Q, Natesan R, Cidre-Aranaz F, Arif S, Liu Y, Rasool RU, Wang P, Mitchell-Velasquez E, Das CK, Vinca E, Cramer Z, Grohar PJ, Chou M, Kumar-Sinha C, Weber K, et al. Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1. Cell Reports. 39: 110971. PMID 35705030 DOI: 10.1016/j.celrep.2022.110971  0.311
2021 Henrich IC, Jain K, Young R, Quick L, Lindsay JM, Park DH, Oliveira AM, Blobel GA, Chou MM. Ubiquitin-specific protease 6 functions as a tumor suppressor in Ewing Sarcoma through immune activation. Cancer Research. PMID 33558334 DOI: 10.1158/0008-5472.CAN-20-1458  0.792
2018 Henrich IC, Young R, Quick L, Oliveira AM, Chou MM. USP6 Confers Sensitivity to IFN-Mediated Apoptosis Through Modulation of TRAIL Signaling in Ewing Sarcoma. Molecular Cancer Research : McR. PMID 30131449 DOI: 10.1158/1541-7786.Mcr-18-0289  0.801
2018 Henrich I, Young R, Quick L, Wang X, Oliveira A, Chou M. Abstract PR08: Ubiquitin-specific protease 6 (USP6) oncogene confers sensitivity of Ewing sarcoma to interferon cytotoxicity Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-Pr08  0.794
2016 Fritchie KJ, Jin L, Wang X, Graham RP, Torbenson MS, Lewis JE, Rivera M, Garcia JJ, Schembri-Wismayer DJ, Westendorf JJ, Chou MM, Dong J, Oliveira AM. Fusion Gene Profile of Biphenotypic Sinonasal Sarcoma: An Analysis of 44 Cases. Histopathology. PMID 27454570 DOI: 10.1111/His.13045  0.325
2016 Quick L, Young R, Henrich IC, Wang X, Asman YW, Oliveira A, Chou MM. Jak1-STAT3 signals are essential effectors of the USP6/TRE17 oncogene in tumorigenesis. Cancer Research. PMID 27440725 DOI: 10.1158/0008-5472.Can-15-2391  0.805
2016 Madan B, Walker MP, Young R, Quick L, Orgel KA, Ryan M, Gupta P, Henrich IC, Ferrer M, Marine S, Roberts BS, Arthur WT, Berndt JD, Oliveira AM, Moon RT, ... ... Chou MM, et al. USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds. Proceedings of the National Academy of Sciences of the United States of America. PMID 27162353 DOI: 10.1073/Pnas.1605691113  0.782
2016 Guo R, Wang X, Chou MM, Yan A, Wenger DE, Al-Ibraheemi A, Molavi DW, Aboulafia A, Jin L, Fritchie K, Oliveira JL, Jenkins RB, Westendorf JJ, Dong J, Oliveira AM. PPP6R3-USP6 Amplification: Novel Oncogenic Mechanism in Malignant Nodular Fasciitis. Genes, Chromosomes & Cancer. PMID 27113271 DOI: 10.1002/Gcc.22366  0.354
2016 Ager C, Reilley M, Nicholas C, Bartkowiak T, Jaiswal A, Curran M, Albershardt TC, Bajaj A, Archer JF, Reeves RS, Ngo LY, Berglund P, ter Meulen J, Denis C, Ghadially H, ... ... Chou M, et al. 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two Journal For Immunotherapy of Cancer. 4. DOI: 10.1186/S40425-016-0173-6  0.72
2015 Bledsoe KL, Stonestrom A, Kadauke S, Quick L, Young R, Blobel GA, Chou MM. Abstract 486: BET protein inhibition by JQ1 blocks EWS-FLI1 activity in Ewing sarcoma Cancer Research. 75: 486-486. DOI: 10.1158/1538-7445.Am2015-486  0.474
2014 Funakoshi Y, Chou MM, Kanaho Y, Donaldson JG. TRE17/USP6 regulates ubiquitylation and trafficking of cargo proteins that enter cells by clathrin-independent endocytosis. Journal of Cell Science. 127: 4750-61. PMID 25179595 DOI: 10.1242/Jcs.156786  0.361
2014 Wang X, Bledsoe KL, Graham RP, Asmann YW, Viswanatha DS, Lewis JE, Lewis JT, Chou MM, Yaszemski MJ, Jen J, Westendorf JJ, Oliveira AM. Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma. Nature Genetics. 46: 666-8. PMID 24859338 DOI: 10.1038/Ng.2989  0.337
2014 Oliveira AM, Chou MM. USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis. Human Pathology. 45: 1-11. PMID 23769422 DOI: 10.1016/J.Humpath.2013.03.005  0.342
2012 Oliveira AM, Chou MM. The TRE17/USP6 oncogene: a riddle wrapped in a mystery inside an enigma. Frontiers in Bioscience (Scholar Edition). 4: 321-34. PMID 22202063 DOI: 10.2741/271  0.456
2012 Pringle LM, Young R, Quick L, Riquelme DN, Oliveira AM, May MJ, Chou MM. Atypical mechanism of NF-κB activation by TRE17/ubiquitin-specific protease 6 (USP6) oncogene and its requirement in tumorigenesis. Oncogene. 31: 3525-35. PMID 22081069 DOI: 10.1038/Onc.2011.520  0.792
2012 Torres-Mora J, Chou MM, Wenger DE, Oliveira AM, Sim FH, Franco M. Aneurysmal bone cyst: An update on recent molecular advances Pathology Case Reviews. 17: 25-30. DOI: 10.1097/Pcr.0B013E31824992D8  0.432
2011 Erickson-Johnson MR, Chou MM, Evers BR, Roth CW, Seys AR, Jin L, Ye Y, Lau AW, Wang X, Oliveira AM. Nodular fasciitis: a novel model of transient neoplasia induced by MYH9-USP6 gene fusion. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 1427-33. PMID 21826056 DOI: 10.1038/Labinvest.2011.118  0.682
2011 Pietschmann MF, Oliveira AM, Chou MM, Ihrler S, Niederhagen M, Baur-Melnyk A, Dürr HR. Aneurysmal bone cysts of soft tissue represent true neoplasms: a report of two cases. The Journal of Bone and Joint Surgery. American Volume. 93: e45. PMID 21543666 DOI: 10.2106/Jbjs.J.00534  0.312
2010 Lau AW, Pringle LM, Quick L, Riquelme DN, Ye Y, Oliveira AM, Chou MM. TRE17/ubiquitin-specific protease 6 (USP6) oncogene translocated in aneurysmal bone cyst blocks osteoblastic maturation via an autocrine mechanism involving bone morphogenetic protein dysregulation. The Journal of Biological Chemistry. 285: 37111-20. PMID 20864534 DOI: 10.1074/Jbc.M110.175133  0.769
2010 Ye Y, Pringle LM, Lau AW, Riquelme DN, Wang H, Jiang T, Lev D, Welman A, Blobel GA, Oliveira AM, Chou MM. TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB. Oncogene. 29: 3619-29. PMID 20418905 DOI: 10.1038/Onc.2010.116  0.772
2010 Kadauke S, Lamonica JM, Lau A, Chou M, Blobel G. A Potential Epigenetic Bookmarking Function for the Hematopoietic Transcription Factor GATA-1. Blood. 116: 2601-2601. DOI: 10.1182/Blood.V116.21.2601.2601  0.667
2009 Blobel GA, Kadauke S, Wang E, Lau AW, Zuber J, Chou MM, Vakoc CR. A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit. Molecular Cell. 36: 970-83. PMID 20064463 DOI: 10.1016/J.Molcel.2009.12.001  0.659
2009 Holloway BA, Gomez de la Torre Canny S, Ye Y, Slusarski DC, Freisinger CM, Dosch R, Chou MM, Wagner DS, Mullins MC. A novel role for MAPKAPK2 in morphogenesis during zebrafish development. Plos Genetics. 5: e1000413. PMID 19282986 DOI: 10.1371/Journal.Pgen.1000413  0.437
2008 Lau AW, Chou MM. The adaptor complex AP-2 regulates post-endocytic trafficking through the non-clathrin Arf6-dependent endocytic pathway. Journal of Cell Science. 121: 4008-17. PMID 19033387 DOI: 10.1242/Jcs.033522  0.667
2008 Sukov WR, Franco MF, Erickson-Johnson M, Chou MM, Unni KK, Wenger DE, Wang X, Oliveira AM. Frequency of USP6 rearrangements in myositis ossificans, brown tumor, and cherubism: molecular cytogenetic evidence that a subset of "myositis ossificans-like lesions" are the early phases in the formation of soft-tissue aneurysmal bone cyst. Skeletal Radiology. 37: 321-7. PMID 18265974 DOI: 10.1007/S00256-007-0442-Z  0.322
2007 Liu J, Lamb D, Chou MM, Liu YJ, Li G. Nerve growth factor-mediated neurite outgrowth via regulation of Rab5. Molecular Biology of the Cell. 18: 1375-84. PMID 17267689 DOI: 10.1091/Mbc.E06-08-0725  0.374
2006 Oliveira AM, Chou MM, Perez-Atayde AR, Rosenberg AE. Aneurysmal bone cyst: a neoplasm driven by upregulation of the USP6 oncogene. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: e1; author reply e2. PMID 16382110 DOI: 10.1200/Jco.2005.04.4818  0.318
2006 Robertson SE, Setty SR, Sitaram A, Marks MS, Lewis RE, Chou MM. Extracellular signal-regulated kinase regulates clathrin-independent endosomal trafficking. Molecular Biology of the Cell. 17: 645-57. PMID 16314390 DOI: 10.1091/Mbc.E05-07-0662  0.701
2005 Shen C, Ye Y, Robertson SE, Lau AW, Mak DO, Chou MM. Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6. The Journal of Biological Chemistry. 280: 35967-73. PMID 16127172 DOI: 10.1074/Jbc.M505220200  0.739
2004 Martinu L, Masuda-Robens JM, Robertson SE, Santy LC, Casanova JE, Chou MM. The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6. Molecular and Cellular Biology. 24: 9752-62. PMID 15509780 DOI: 10.1128/Mcb.24.22.9752-9762.2004  0.756
2003 Chou MM, Masuda-Robens JM, Gupta ML. Cdc42 promotes G1 progression through p70 S6 kinase-mediated induction of cyclin E expression. The Journal of Biological Chemistry. 278: 35241-7. PMID 12842876 DOI: 10.1074/Jbc.M305246200  0.783
2003 Masuda-Robens JM, Kutney SN, Qi H, Chou MM. The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling. Molecular and Cellular Biology. 23: 2151-61. PMID 12612085 DOI: 10.1128/Mcb.23.6.2151-2161.2003  0.778
2003 Baumeister MA, Martinu L, Rossman KL, Sondek J, Lemmon MA, Chou MM. Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting. The Journal of Biological Chemistry. 278: 11457-64. PMID 12525493 DOI: 10.1074/Jbc.M211901200  0.309
2002 Martinu L, Santiago-Walker A, Qi H, Chou MM. Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre. The Journal of Biological Chemistry. 277: 50996-1002. PMID 12399475 DOI: 10.1074/Jbc.M204869200  0.407
2002 Goncharova EA, Goncharov DA, Eszterhas A, Hunter DS, Glassberg MK, Yeung RS, Walker CL, Noonan D, Kwiatkowski DJ, Chou MM, Panettieri RA, Krymskaya VP. Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM). The Journal of Biological Chemistry. 277: 30958-67. PMID 12045200 DOI: 10.1074/Jbc.M202678200  0.424
2001 Masuda-Robens J, Krymskaya VP, Qi H, Chou MM. Assays for monitoring p70 S6 kinase and RSK activation. Methods in Enzymology. 333: 45-55. PMID 11400353 DOI: 10.1016/S0076-6879(01)33043-4  0.765
2000 Coghlan MP, Chou MM, Carpenter CL. Atypical protein kinases Clambda and -zeta associate with the GTP-binding protein Cdc42 and mediate stress fiber loss. Molecular and Cellular Biology. 20: 2880-9. PMID 10733591 DOI: 10.1128/Mcb.20.8.2880-2889.2000  0.38
1998 Chou MM, Hou W, Johnson J, Graham LK, Lee MH, Chen CS, Newton AC, Schaffhausen BS, Toker A. Regulation of protein kinase C zeta by PI 3-kinase and PDK-1. Current Biology : Cb. 8: 1069-77. PMID 9768361 DOI: 10.1016/S0960-9822(98)70444-0  0.383
1998 Nikolic M, Chou MM, Lu W, Mayer BJ, Tsai LH. The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity. Nature. 395: 194-8. PMID 9744280 DOI: 10.1038/26034  0.346
1996 Watson KL, Chou MM, Blenis J, Gelbart WM, Erikson RL. A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene. Proceedings of the National Academy of Sciences of the United States of America. 93: 13694-8. PMID 8942996 DOI: 10.1073/Pnas.93.24.13694  0.695
1996 Grammer TC, Cheatham L, Chou MM, Blenis J. The p70S6K signalling pathway: a novel signalling system involved in growth regulation. Cancer Surveys. 27: 271-92. PMID 8909805  0.596
1996 Chou MM, Blenis J. The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1. Cell. 85: 573-83. PMID 8653792 DOI: 10.1016/S0092-8674(00)81257-X  0.646
1995 Chou MM, Blenis J. The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling. Current Opinion in Cell Biology. 7: 806-14. PMID 8608011 DOI: 10.1016/0955-0674(95)80064-6  0.627
1995 Cheatham L, Monfar M, Chou MM, Blenis J. Structural and functional analysis of pp70S6k. Proceedings of the National Academy of Sciences of the United States of America. 92: 11696-700. PMID 8524831 DOI: 10.1073/Pnas.92.25.11696  0.61
1995 Chou MM, Hanafusa H. A novel ligand for SH3 domains. The Nck adaptor protein binds to a serine/threonine kinase via an SH3 domain. The Journal of Biological Chemistry. 270: 7359-64. PMID 7706279 DOI: 10.1074/Jbc.270.13.7359  0.561
1992 Chou MM, Eduardo Fajardo J, Hanafusa H. The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels Molecular and Cellular Biology. 12: 5834-5842. PMID 1280326 DOI: 10.1128/Mcb.12.12.5834  0.594
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