Philip J. Gage - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Molecular Biology, Genetics, Cell Biology

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Seo S, Chen L, Liu W, Zhao D, Schultz KM, Sasman A, Liu T, Zhang HF, Gage PJ, Kume T. Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development. Investigative Ophthalmology & Visual Science. 58: 1368-1377. PMID 28253399 DOI: 10.1167/Iovs.16-21217  0.451
2016 Davis SW, Mortensen AH, Keisler JL, Zacharias AL, Gage PJ, Yamamura K, Camper SA. β-catenin is required in the neural crest and mesencephalon for pituitary gland organogenesis. Bmc Developmental Biology. 16: 16. PMID 27184910 DOI: 10.1186/S12861-016-0118-9  0.71
2016 Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ. AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development. Investigative Ophthalmology & Visual Science. 57: 1072-1081. PMID 26968737 DOI: 10.1167/Iovs.15-18103  0.448
2015 Gage PJ, Hurd EA, Martin DM. Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome. Investigative Ophthalmology & Visual Science. 56: 7923-30. PMID 26670829 DOI: 10.1167/Iovs.15-18069  0.332
2014 French CR, Seshadri S, Destefano AL, Fornage M, Arnold CR, Gage PJ, Skarie JM, Dobyns WB, Millen KJ, Liu T, Dietz W, Kume T, Hofker M, Emery DJ, Childs SJ, et al. Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease. The Journal of Clinical Investigation. 124: 4877-81. PMID 25250569 DOI: 10.1172/Jci75109  0.329
2014 Gage PJ, Kuang C, Zacharias AL. The homeodomain transcription factor PITX2 is required for specifying correct cell fates and establishing angiogenic privilege in the developing cornea. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 1391-400. PMID 25044936 DOI: 10.1002/Dvdy.24165  0.725
2012 Al Alam D, Sala FG, Baptista S, Galzote R, Danopoulos S, Tiozzo C, Gage P, Grikscheit T, Warburton D, Frey MR, Bellusci S. FGF9-Pitx2-FGF10 signaling controls cecal formation in mice. Developmental Biology. 369: 340-8. PMID 22819677 DOI: 10.1016/J.Ydbio.2012.07.008  0.42
2011 Plageman TF, Zacharias AL, Gage PJ, Lang RA. Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis. Developmental Biology. 357: 227-34. PMID 21726547 DOI: 10.1016/J.Ydbio.2011.06.027  0.713
2011 Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ. Pitx2 is an upstream activator of extraocular myogenesis and survival Developmental Biology. 349: 395-405. PMID 21035439 DOI: 10.1016/J.Ydbio.2010.10.028  0.698
2010 Zacharias AL, Gage PJ. Canonical Wnt/β-catenin signaling is required for maintenance but not activation of Pitx2 expression in neural crest during eye development Developmental Dynamics. 239: 3215-3225. PMID 20960542 DOI: 10.1002/Dvdy.22459  0.737
2010 Bassett EA, Williams T, Zacharias AL, Gage PJ, Fuhrmann S, West-Mays JA. AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis. Human Molecular Genetics. 19: 1791-804. PMID 20150232 DOI: 10.1093/Hmg/Ddq060  0.702
2009 Acharya M, Lingenfelter DJ, Huang L, Gage PJ, Walter MA. Human PRKC apoptosis WT1 regulator is a novel PITX2-interacting protein that regulates PITX2 transcriptional activity in ocular cells. The Journal of Biological Chemistry. 284: 34829-38. PMID 19801652 DOI: 10.1074/Jbc.M109.006684  0.396
2009 Gage PJ, Zacharias AL. Signaling "cross-talk" is integrated by transcription factors in the development of the anterior segment in the eye Developmental Dynamics. 238: 2149-2162. PMID 19623614 DOI: 10.1002/Dvdy.22033  0.725
2008 Gage PJ, Qian M, Wu D, Rosenberg KI. The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Developmental Biology. 317: 310-24. PMID 18367164 DOI: 10.1016/J.Ydbio.2008.02.030  0.464
2008 Tessari A, Pietrobon M, Notte A, Cifelli G, Gage PJ, Schneider MD, Lembo G, Campione M. Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs. Circulation Research. 102: 813-22. PMID 18292603 DOI: 10.1161/Circresaha.107.163188  0.303
2007 L'Honoré A, Coulon V, Marcil A, Lebel M, Lafrance-Vanasse J, Gage P, Camper S, Drouin J. Sequential expression and redundancy of Pitx2 and Pitx3 genes during muscle development. Developmental Biology. 307: 421-33. PMID 17540357 DOI: 10.1016/J.Ydbio.2007.04.034  0.368
2006 Ai D, Liu W, Ma L, Dong F, Lu MF, Wang D, Verzi MP, Cai C, Gage PJ, Evans S, Black BL, Brown NA, Martin JF. Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium. Developmental Biology. 296: 437-49. PMID 16836994 DOI: 10.1016/J.Ydbio.2006.06.009  0.329
2006 Sclafani AM, Skidmore JM, Ramaprakash H, Trumpp A, Gage PJ, Martin DM. Nestin-Cre mediated deletion of Pitx2 in the mouse. Genesis (New York, N.Y. : 2000). 44: 336-44. PMID 16823861 DOI: 10.1002/Dvg.20220  0.348
2006 Diehl AG, Zareparsi S, Qian M, Khanna R, Angeles R, Gage PJ. Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose. Investigative Ophthalmology & Visual Science. 47: 1785-93. PMID 16638982 DOI: 10.1167/Iovs.05-1424  0.346
2006 Nowotschin S, Liao J, Gage PJ, Epstein JA, Campione M, Morrow BE. Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field. Development (Cambridge, England). 133: 1565-73. PMID 16556915 DOI: 10.1242/Dev.02309  0.344
2006 Zhang HZ, Degar BA, Rogoulina S, Resor C, Booth CJ, Sinning J, Gage PJ, Forget BG. Hematopoiesis following disruption of the Pitx2 homeodomain gene. Experimental Hematology. 34: 167-78. PMID 16459185 DOI: 10.1016/J.Exphem.2005.11.002  0.359
2006 Berry FB, Lines MA, Oas JM, Footz T, Underhill DA, Gage PJ, Walter MA. Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld-Rieger syndrome and anterior segment dysgenesis. Human Molecular Genetics. 15: 905-19. PMID 16449236 DOI: 10.1093/Hmg/Ddl008  0.33
2006 Kieusseian A, Chagraoui J, Kerdudo C, Mangeot PE, Gage PJ, Navarro N, Izac B, Uzan G, Forget BG, Dubart-Kupperschmitt A. Expression of Pitx2 in stromal cells is required for normal hematopoiesis. Blood. 107: 492-500. PMID 16195330 DOI: 10.1182/Blood-2005-02-0529  0.365
2006 Evans AL, Gage PJ. The essential role of Pitx2 in extraocular muscle development Developmental Biology. 295: 384-385. DOI: 10.1016/J.Ydbio.2006.04.180  0.313
2005 Gage PJ, Rhoades W, Prucka SK, Hjalt T. Fate maps of neural crest and mesoderm in the mammalian eye. Investigative Ophthalmology & Visual Science. 46: 4200-8. PMID 16249499 DOI: 10.1167/Iovs.05-0691  0.363
2005 Evans AL, Gage PJ. Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development. Human Molecular Genetics. 14: 3347-59. PMID 16203745 DOI: 10.1093/Hmg/Ddi365  0.45
2005 Charles MA, Suh H, Hjalt TA, Drouin J, Camper SA, Gage PJ. PITX genes are required for cell survival and Lhx3 activation. Molecular Endocrinology (Baltimore, Md.). 19: 1893-903. PMID 15761027 DOI: 10.1210/Me.2005-0052  0.437
2004 Mandal MN, Ambasudhan R, Wong PW, Gage PJ, Sieving PA, Ayyagari R. Characterization of mouse orthologue of ELOVL4: genomic organization and spatial and temporal expression. Genomics. 83: 626-35. PMID 15028285 DOI: 10.1016/J.Ygeno.2003.09.020  0.341
2004 Martin DM, Skidmore JM, Philips ST, Vieira C, Gage PJ, Condie BG, Raphael Y, Martinez S, Camper SA. PITX2 is required for normal development of neurons in the mouse subthalamic nucleus and midbrain. Developmental Biology. 267: 93-108. PMID 14975719 DOI: 10.1016/J.Ydbio.2003.10.035  0.399
2002 Martin DM, Skidmore JM, Fox SE, Gage PJ, Camper SA. Pitx2 distinguishes subtypes of terminally differentiated neurons in the developing mouse neuroepithelium. Developmental Biology. 252: 84-99. PMID 12453462 DOI: 10.1006/Dbio.2002.0835  0.342
2002 Suh H, Gage PJ, Drouin J, Camper SA. Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification. Development (Cambridge, England). 129: 329-37. PMID 11807026  0.312
1997 Gage PJ, Camper SA. Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation Human Molecular Genetics. 6: 457-464. PMID 9147650 DOI: 10.1093/Hmg/6.3.457  0.375
1996 Gage PJ, Brinkmeier ML, Scarlett LM, Knapp LT, Camper SA, Mahon KA. The Ames dwarf gene, df, is required early in pituitary ontogeny for the extinction of Rpx transcription and initiation of lineage-specific cell proliferation. Molecular Endocrinology (Baltimore, Md.). 10: 1570-81. PMID 8961267 DOI: 10.1210/Mend.10.12.8961267  0.405
1995 Gage PJ, Lossie AC, Scarlett LM, Lloyd RV, Camper SA. Ames dwarf mice exhibit somatotrope commitment but lack growth hormone-releasing factor response Endocrinology. 136: 1161-1167. PMID 7867569 DOI: 10.1210/Endo.136.3.7867569  0.308
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