G. Yancey Gillespie, Ph.D. - Publications

Affiliations: 
Immunology, Surgery University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
cytosine deaminase, UPRT, PNP; HSV that include TNFa, IL-2, IL-4, IL-5, IL-10, IL12, IL-16
Website:
http://www.uab.edu/medicine/immunology/faculty/100-gillespie

97 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ahluwalia MS, Bou-Anak S, Burgett ME, Sarmey N, Khosla D, Dahiya S, Weil RJ, Bae E, Huang P, McGraw M, Grove LM, Olman MA, Prayson RA, Suh JH, Gillespie GY, et al. Correlation of higher levels of soluble TNF-R1 with a shorter survival, independent of age, in recurrent glioblastoma. Journal of Neuro-Oncology. PMID 27858267 DOI: 10.1007/s11060-016-2319-2  0.76
2016 Waters AM, Stafman LL, Garner EF, Mruthyunjayappa S, Stewart JE, Friedman GK, Coleman JM, Markert JM, Gillespie GY, Beierle EA. Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma. Translational Oncology. 9: 419-430. PMID 27751346 DOI: 10.1016/j.tranon.2016.07.008  0.76
2016 Bauer DF, Pereboeva L, Gillespie GY, Cloud GA, Elzafarany O, Langford C, Markert JM, Jr LS. Effect of HSV-IL12 Loaded Tumor Cell-Based Vaccination in a Mouse Model of High-Grade Neuroblastoma. Journal of Immunology Research. 2016: 2568125. PMID 27610392 DOI: 10.1155/2016/2568125  0.76
2016 Patel DM, Foreman PM, Nabors LB, Riley KO, Gillespie GY, Markert JM. Design of a Phase I Clinical Trial to Evaluate M032, a Genetically Engineered HSV-1 Expressing IL-12, in Patients with Recurrent/Progressive Glioblastoma Multiforme, Anaplastic Astrocytoma, or Gliosarcoma. Human Gene Therapy. Clinical Development. 27: 69-78. PMID 27314913 DOI: 10.1089/humc.2016.031  0.76
2015 Dobbins GC, Ugai H, Curiel DT, Gillespie GY. A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents. Plos One. 10: e0145272. PMID 26689910 DOI: 10.1371/journal.pone.0145272  0.76
2015 Lobo MR, Kukino A, Tran H, Schabel MC, Springer CS, Gillespie GY, Grafe MR, Woltjer RL, Pike MM. Synergistic Antivascular and Antitumor Efficacy with Combined Cediranib and SC6889 in Intracranial Mouse Glioma. Plos One. 10: e0144488. PMID 26645398 DOI: 10.1371/journal.pone.0144488  0.76
2015 Willey CD, Gilbert AN, Anderson JC, Gillespie GY. Patient-Derived Xenografts as a Model System for Radiation Research. Seminars in Radiation Oncology. 25: 273-80. PMID 26384275 DOI: 10.1016/j.semradonc.2015.05.008  0.76
2015 Tilson SG, Haley EM, Triantafillu UL, Dozier DA, Langford CP, Gillespie GY, Kim Y. ROCK Inhibition Facilitates In Vitro Expansion of Glioblastoma Stem-Like Cells. Plos One. 10: e0132823. PMID 26167936 DOI: 10.1371/journal.pone.0132823  0.76
2015 Warram JM, de Boer E, Korb M, Hartman Y, Kovar J, Markert JM, Gillespie GY, Rosenthal EL. Fluorescence-guided resection of experimental malignant glioma using cetuximab-IRDye 800CW. British Journal of Neurosurgery. 1-9. PMID 26073144 DOI: 10.3109/02688697.2015.1056090  0.76
2015 Beck BH, Kim H, O'Brien R, Jadus MR, Gillespie GY, Cloud GA, Hoa NT, Langford CP, Lopez RD, Harkins LE, Lamb LS. Dynamics of Circulating γδ T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma. Plos One. 10: e0122387. PMID 25955158 DOI: 10.1371/journal.pone.0122387  0.76
2015 Friedman GK, Nan L, Haas MC, Kelly VM, Moore BP, Langford CP, Xu H, Han X, Beierle EA, Markert JM, Cassady KA, Gillespie GY. γ₁34.5-deleted HSV-1-expressing human cytomegalovirus IRS1 gene kills human glioblastoma cells as efficiently as wild-type HSV-1 in normoxia or hypoxia. Gene Therapy. 22: 348-55. PMID 25427614 DOI: 10.1038/gt.2014.107  0.76
2014 Lobo MR, Wang X, Gillespie GY, Woltjer RL, Pike MM. Combined efficacy of cediranib and quinacrine in glioma is enhanced by hypoxia and causally linked to autophagic vacuole accumulation. Plos One. 9: e114110. PMID 25490024 DOI: 10.1371/journal.pone.0114110  0.76
2014 Jackson JD, McMorris AM, Roth JC, Coleman JM, Whitley RJ, Gillespie GY, Carroll SL, Markert JM, Cassady KA. Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral nerve sheath tumor cell lines. Gene Therapy. 21: 984-90. PMID 25119379 DOI: 10.1038/gt.2014.72  0.76
2014 Han X, Zhang W, Yang X, Wheeler CG, Langford CP, Wu L, Filippova N, Friedman GK, Ding Q, Fathallah-Shaykh HM, Gillespie GY, Nabors LB. The role of Src family kinases in growth and migration of glioma stem cells. International Journal of Oncology. 45: 302-10. PMID 24819299 DOI: 10.3892/ijo.2014.2432  0.76
2014 Han X, Li R, Zhang W, Yang X, Wheeler CG, Friedman GK, Province P, Ding Q, You Z, Fathallah-Shaykh HM, Gillespie GY, Zhao X, King PH, Nabors LB. Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro. Journal of Neuro-Oncology. 118: 61-72. PMID 24664369 DOI: 10.1007/s11060-014-1419-0  0.76
2014 Roth JC, Cassady KA, Cody JJ, Parker JN, Price KH, Coleman JM, Peggins JO, Noker PE, Powers NW, Grimes SD, Carroll SL, Gillespie GY, Whitley RJ, Markert JM. Evaluation of the safety and biodistribution of M032, an attenuated herpes simplex virus type 1 expressing hIL-12, after intracerebral administration to aotus nonhuman primates. Human Gene Therapy. Clinical Development. 25: 16-27. PMID 24649838 DOI: 10.1089/humc.2013.201  0.76
2014 Markert JM, Razdan SN, Kuo HC, Cantor A, Knoll A, Karrasch M, Nabors LB, Markiewicz M, Agee BS, Coleman JM, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Weichselbaum RR, ... ... Gillespie GY, et al. A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1048-55. PMID 24572293 DOI: 10.1038/mt.2014.22  0.76
2014 Megison ML, Gillory LA, Stewart JE, Nabers HC, Mroczek-Musulman E, Waters AM, Coleman JM, Kelly V, Markert JM, Gillespie GY, Friedman GK, Beierle EA. Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of pediatric solid tumors. Plos One. 9: e86843. PMID 24497984 DOI: 10.1371/journal.pone.0086843  0.76
2013 Gillory LA, Megison ML, Stewart JE, Mroczek-Musulman E, Nabers HC, Waters AM, Kelly V, Coleman JM, Markert JM, Gillespie GY, Friedman GK, Beierle EA. Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma. Plos One. 8: e77753. PMID 24130898 DOI: 10.1371/journal.pone.0077753  0.76
2013 Lobo MR, Green SC, Schabel MC, Gillespie GY, Woltjer RL, Pike MM. Quinacrine synergistically enhances the antivascular and antitumor efficacy of cediranib in intracranial mouse glioma. Neuro-Oncology. 15: 1673-83. PMID 24092859 DOI: 10.1093/neuonc/not119  0.76
2013 Knight A, Arnouk H, Britt W, Gillespie GY, Cloud GA, Harkins L, Su Y, Lowdell MW, Lamb LS. CMV-independent lysis of glioblastoma by ex vivo expanded/activated Vδ1+ γδ T cells. Plos One. 8: e68729. PMID 23950874 DOI: 10.1371/journal.pone.0068729  0.76
2013 Griguer CE, Cantor AB, Fathallah-Shaykh HM, Gillespie GY, Gordon AS, Markert JM, Radovanovic I, Clement-Schatlo V, Shannon CN, Oliva CR. Prognostic relevance of cytochrome C oxidase in primary glioblastoma multiforme. Plos One. 8: e61035. PMID 23593382 DOI: 10.1371/journal.pone.0061035  0.76
2013 Friedman GK, Raborn J, Kelly VM, Cassady KA, Markert JM, Gillespie GY. Pediatric glioma stem cells: biologic strategies for oncolytic HSV virotherapy. Frontiers in Oncology. 3: 28. PMID 23450706 DOI: 10.3389/fonc.2013.00028  0.76
2013 Lamb LS, Bowersock J, Dasgupta A, Gillespie GY, Su Y, Johnson A, Spencer HT. Engineered drug resistant γδ T cells kill glioblastoma cell lines during a chemotherapy challenge: a strategy for combining chemo- and immunotherapy. Plos One. 8: e51805. PMID 23326319 DOI: 10.1371/journal.pone.0051805  0.76
2013 Pressey JG, Haas MC, Pressey CS, Kelly VM, Parker JN, Gillespie GY, Friedman GK. CD133 marks a myogenically primitive subpopulation in rhabdomyosarcoma cell lines that are relatively chemoresistant but sensitive to mutant HSV. Pediatric Blood & Cancer. 60: 45-52. PMID 22408058 DOI: 10.1002/pbc.24117  0.76
2012 Jarboe JS, Anderson JC, Duarte CW, Mehta T, Nowsheen S, Hicks PH, Whitley AC, Rohrbach TD, McCubrey RO, Chiu S, Burleson TM, Bonner JA, Gillespie GY, Yang ES, Willey CD. MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3030-41. PMID 22619307 DOI: 10.1158/1078-0432.CCR-11-3091  0.76
2012 Friedman GK, Cassady KA, Beierle EA, Markert JM, Gillespie GY. Targeting pediatric cancer stem cells with oncolytic virotherapy. Pediatric Research. 71: 500-10. PMID 22430386 DOI: 10.1038/pr.2011.58  0.76
2012 Markert JM, Cody JJ, Parker JN, Coleman JM, Price KH, Kern ER, Quenelle DC, Lakeman AD, Schoeb TR, Palmer CA, Cartner SC, Gillespie GY, Whitley RJ. Preclinical evaluation of a genetically engineered herpes simplex virus expressing interleukin-12. Journal of Virology. 86: 5304-13. PMID 22379082 DOI: 10.1128/JVI.06998-11  0.76
2012 Duarte CW, Willey CD, Zhi D, Cui X, Harris JJ, Vaughan LK, Mehta T, McCubrey RO, Khodarev NN, Weichselbaum RR, Gillespie GY. Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner. Plos One. 7: e29653. PMID 22242177 DOI: 10.1371/journal.pone.0029653  0.76
2012 Friedman GK, Haas MC, Kelly VM, Markert JM, Gillespie GY, Cassady KA. Hypoxia moderates γ134.5-deleted herpes simplex virus oncolytic activity in human glioma xenoline primary cultures Translational Oncology. 5: 200-207. DOI: 10.1593/tlo.12115  0.76
2011 McFarland BC, Ma JY, Langford CP, Gillespie GY, Yu H, Zheng Y, Nozell SE, Huszar D, Benveniste EN. Therapeutic potential of AZD1480 for the treatment of human glioblastoma. Molecular Cancer Therapeutics. 10: 2384-93. PMID 22027691 DOI: 10.1158/1535-7163.MCT-11-0480  0.76
2011 Oliva CR, Moellering DR, Gillespie GY, Griguer CE. Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production. Plos One. 6: e24665. PMID 21931801 DOI: 10.1371/journal.pone.0024665  0.76
2011 Wang D, Olman MA, Stewart J, Tipps R, Huang P, Sanders PW, Toline E, Prayson RA, Lee J, Weil RJ, Palmer CA, Gillespie GY, Liu WM, Pieper RO, Guan JL, et al. Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity. Plos One. 6: e19629. PMID 21602932 DOI: 10.1371/journal.pone.0019629  0.76
2011 Advani SJ, Markert JM, Sood RF, Samuel S, Gillespie GY, Shao MY, Roizman B, Weichselbaum RR. Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1. Gene Therapy. 18: 1098-102. PMID 21544094 DOI: 10.1038/gt.2011.61  0.76
2011 Filippova N, Yang X, Wang Y, Gillespie GY, Langford C, King PH, Wheeler C, Nabors LB. The RNA-binding protein HuR promotes glioma growth and treatment resistance. Molecular Cancer Research : McR. 9: 648-59. PMID 21498545 DOI: 10.1158/1541-7786.MCR-10-0325  0.76
2011 Friedman GK, Gillespie GY. Cancer Stem Cells and Pediatric Solid Tumors. Cancers. 3: 298-318. PMID 21394230 DOI: 10.3390/cancers3010298  0.76
2011 Sun M, Song L, Zhou T, Gillespie GY, Jope RS. The role of DDX3 in regulating Snail. Biochimica Et Biophysica Acta. 1813: 438-47. PMID 21237216 DOI: 10.1016/j.bbamcr.2011.01.003  0.76
2011 Bryant NL, Gillespie GY, Lopez RD, Markert JM, Cloud GA, Langford CP, Arnouk H, Su Y, Haines HL, Suarez-Cuervo C, Lamb LS. Preclinical evaluation of ex vivo expanded/activated γδ T cells for immunotherapy of glioblastoma multiforme. Journal of Neuro-Oncology. 101: 179-88. PMID 20532954 DOI: 10.1007/s11060-010-0245-2  0.76
2010 Oliva CR, Nozell SE, Diers A, McClugage SG, Sarkaria JN, Markert JM, Darley-Usmar VM, Bailey SM, Gillespie GY, Landar A, Griguer CE. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. The Journal of Biological Chemistry. 285: 39759-67. PMID 20870728 DOI: 10.1074/jbc.M110.147504  0.76
2010 Nabors LB, Fiveash JB, Markert JM, Kekan MS, Gillespie GY, Huang Z, Johnson MJ, Meleth S, Kuo H, Gladson CL, Fathallah-Shaykh HM. A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma. Archives of Neurology. 67: 313-9. PMID 20212229 DOI: 10.1001/archneurol.2010.16  0.76
2009 Friedman GK, Pressey JG, Reddy AT, Markert JM, Gillespie GY. Herpes simplex virus oncolytic therapy for pediatric malignancies. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1125-35. PMID 19367259 DOI: 10.1038/mt.2009.73  0.76
2009 Kaliberova LN, Krendelchtchikova V, Harmon DK, Stockard CR, Petersen AS, Markert JM, Gillespie GY, Grizzle WE, Buchsbaum DJ, Kaliberov SA. CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma. Cancer Gene Therapy. 16: 794-805. PMID 19363468 DOI: 10.1038/cgt.2009.23  0.76
2009 Pike MM, Stoops CN, Langford CP, Akella NS, Nabors LB, Gillespie GY. High-resolution longitudinal assessment of flow and permeability in mouse glioma vasculature: Sequential small molecule and SPIO dynamic contrast agent MRI. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 61: 615-25. PMID 19235262 DOI: 10.1002/mrm.21931  0.76
2009 Bryant NL, Suarez-Cuervo C, Gillespie GY, Markert JM, Nabors LB, Meleth S, Lopez RD, Lamb LS. Characterization and immunotherapeutic potential of gammadelta T-cells in patients with glioblastoma. Neuro-Oncology. 11: 357-67. PMID 19211933 DOI: 10.1215/15228517-2008-111  0.76
2009 Markert JM, Liechty PG, Wang W, Gaston S, Braz E, Karrasch M, Nabors LB, Markiewicz M, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Gillespie GY. Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 199-207. PMID 18957964 DOI: 10.1038/mt.2008.228  0.76
2008 Brantley EC, Nabors LB, Gillespie GY, Choi YH, Palmer CA, Harrison K, Roarty K, Benveniste EN. Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 4694-704. PMID 18676737 DOI: 10.1158/1078-0432.CCR-08-0618  0.76
2008 Fiveash JB, Gillespie GY, Oliver PG, Zhou T, Belenky ML, Buchsbaum DJ. Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5. International Journal of Radiation Oncology, Biology, Physics. 71: 507-16. PMID 18474311 DOI: 10.1016/j.ijrobp.2008.02.005  0.76
2008 Suswam E, Li Y, Zhang X, Gillespie GY, Li X, Shacka JJ, Lu L, Zheng L, King PH. Tristetraprolin down-regulates interleukin-8 and vascular endothelial growth factor in malignant glioma cells. Cancer Research. 68: 674-82. PMID 18245466 DOI: 10.1158/0008-5472.CAN-07-2751  0.76
2008 Fiveash J, Buchsbaum D, Gillespie GY. In Reply to Dr. Speer International Journal of Radiation Oncology Biology Physics. 72: 1274. DOI: 10.1016/j.ijrobp.2008.07.045  0.76
2007 Van Houdt WJ, Wu H, Glasgow JN, Lamfers ML, Dirven CM, Gillespie GY, Curiel DT, Haviv YS. Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models. Neuro-Oncology. 9: 280-90. PMID 17522331 DOI: 10.1215/15228517-2007-017  0.76
2007 Radbill AE, Reddy AT, Markert JM, Wyss JM, Pike MM, Akella NS, Bharara N, Gillespie GY. Effects of G207, a conditionally replication-competent oncolytic herpes simplex virus, on the developing mammalian brain. Journal of Neurovirology. 13: 118-29. PMID 17505980 DOI: 10.1080/13550280601187177  0.76
2007 Kaliberov SA, Market JM, Gillespie GY, Krendelchtchikova V, Della Manna D, Sellers JC, Kaliberova LN, Black ME, Buchsbaum DJ. Mutation of Escherichia coli cytosine deaminase significantly enhances molecular chemotherapy of human glioma. Gene Therapy. 14: 1111-9. PMID 17495948 DOI: 10.1038/sj.gt.3302965  0.76
2007 Shah AC, Parker JN, Gillespie GY, Lakeman FD, Meleth S, Markert JM, Cassady KA. Enhanced antiglioma activity of chimeric HCMV/HSV-1 oncolytic viruses. Gene Therapy. 14: 1045-54. PMID 17429445 DOI: 10.1038/sj.gt.3302942  0.76
2007 Khwaja FW, Reed MS, Olson JJ, Schmotzer BJ, Gillespie GY, Guha A, Groves MD, Kesari S, Pohl J, Van Meir EG. Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients. Journal of Proteome Research. 6: 559-70. PMID 17269713 DOI: 10.1021/pr060240z  0.76
2007 Tang Y, Han T, Everts M, Zhu ZB, Gillespie GY, Curiel DT, Wu H. Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model. Gene Therapy. 14: 523-32. PMID 17167498 DOI: 10.1038/sj.gt.3302888  0.76
2007 Guffey MB, Parker JN, Luckett WS, Gillespie GY, Meleth S, Whitley RJ, Markert JM. Engineered herpes simplex virus expressing bacterial cytosine deaminase for experimental therapy of brain tumors. Cancer Gene Therapy. 14: 45-56. PMID 16990846 DOI: 10.1038/sj.cgt.7700978  0.76
2007 Griguer CE, Oliva CR, Gillespie GY, Gobin E, Marcorelles P, Yancey Gillespie G. Pharmacologic manipulations of mitochondrial membrane potential (DeltaPsim) selectively in glioma cells. Journal of Neuro-Oncology. 81: 9-20. PMID 16862448 DOI: 10.1007/s11060-006-9201-6  0.76
2006 Markert JM, Parker JN, Buchsbaum DJ, Grizzle WE, Gillespie GY, Whitley RJ. Oncolytic HSV-1 for the treatment of brain tumours. Herpes : the Journal of the Ihmf. 13: 66-71. PMID 17147910  0.76
2006 Shah AC, Price KH, Parker JN, Samuel SL, Meleth S, Cassady KA, Gillespie GY, Whitley RJ, Markert JM. Serial passage through human glioma xenografts selects for a Deltagamma134.5 herpes simplex virus type 1 mutant that exhibits decreased neurotoxicity and prolongs survival of mice with experimental brain tumors. Journal of Virology. 80: 7308-15. PMID 16840311 DOI: 10.1128/JVI.00725-06  0.76
2006 Grunda JM, Nabors LB, Palmer CA, Chhieng DC, Steg A, Mikkelsen T, Diasio RB, Zhang K, Allison D, Grizzle WE, Wang W, Gillespie GY, Johnson MR. Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM). Journal of Neuro-Oncology. 80: 261-74. PMID 16773218 DOI: 10.1007/s11060-006-9191-4  0.76
2006 Kim KJ, Wang L, Su YC, Gillespie GY, Salhotra A, Lal B, Laterra J. Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1292-8. PMID 16489086 DOI: 10.1158/1078-0432.CCR-05-1793  0.76
2006 Griguer CE, Oliva CR, Kelley EE, Giles GI, Lancaster JR, Gillespie GY. Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells. Cancer Research. 66: 2257-63. PMID 16489029 DOI: 10.1158/0008-5472.CAN-05-3364  0.76
2006 Akella NS, Ding Q, Menegazzo I, Wang W, Gillespie GY, Grammer JR, Gladson CL, Nabors LB. A novel technique to quantify glioma tumor invasion using serial microscopy sections. Journal of Neuroscience Methods. 153: 183-9. PMID 16406041 DOI: 10.1016/j.jneumeth.2005.10.026  0.76
2006 Parker JN, Pfister LA, Quenelle D, Gillespie GY, Markert JM, Kern ER, Whitley RJ. Genetically engineered herpes simplex viruses that express IL-12 or GM-CSF as vaccine candidates. Vaccine. 24: 1644-52. PMID 16243413 DOI: 10.1016/j.vaccine.2005.09.051  0.76
2006 Chen SH, Gillespie GY, Benveniste EN. Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases. Glia. 53: 191-200. PMID 16206166 DOI: 10.1002/glia.20264  0.76
2005 Banks JT, Bharara S, Tubbs RS, Wolff CL, Gillespie GY, Markert JM, Blount JP. Polymerase chain reaction for the rapid detection of cerebrospinal fluid shunt or ventriculostomy infections. Neurosurgery. 57: 1237-43; discussion . PMID 16331172 DOI: 10.1227/01.NEU.0000186038.98817.72  0.76
2005 Griguer CE, Oliva CR, Gillespie GY. Glucose metabolism heterogeneity in human and mouse malignant glioma cell lines. Journal of Neuro-Oncology. 74: 123-33. PMID 16193382 DOI: 10.1007/s11060-004-6404-6  0.76
2005 Chung WJ, Lyons SA, Nelson GM, Hamza H, Gladson CL, Gillespie GY, Sontheimer H. Inhibition of cystine uptake disrupts the growth of primary brain tumors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7101-10. PMID 16079392 DOI: 10.1523/JNEUROSCI.5258-04.2005  0.76
2005 Hellums EK, Markert JM, Parker JN, He B, Perbal B, Roizman B, Whitley RJ, Langford CP, Bharara S, Gillespie GY. Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro-Oncology. 7: 213-24. PMID 16053696 DOI: 10.1215/S1152851705000074  0.76
2005 Stettner MR, Wang W, Nabors LB, Bharara S, Flynn DC, Grammer JR, Gillespie GY, Gladson CL. Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells. Cancer Research. 65: 5535-43. PMID 15994925 DOI: 10.1158/0008-5472.CAN-04-3688  0.76
2005 Bharara S, Sorscher EJ, Gillespie GY, Lindsey JR, Hong JS, Curlee KV, Allan PW, Gadi VK, Alexander SA, Secrist JA, Parker WB, Waud WR. Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy. Human Gene Therapy. 16: 339-47. PMID 15812229 DOI: 10.1089/hum.2005.16.339  0.76
2005 Shen S, Khazaeli MB, Gillespie GY, Alvarez VL. Radiation dosimetry of 131I-chlorotoxin for targeted radiotherapy in glioma-bearing mice. Journal of Neuro-Oncology. 71: 113-9. PMID 15690125 DOI: 10.1007/s11060-004-0890-4  0.76
2005 Parker JN, Meleth S, Hughes KB, Gillespie GY, Whitley RJ, Markert JM. Enhanced inhibition of syngeneic murine tumors by combinatorial therapy with genetically engineered HSV-1 expressing CCL2 and IL-12. Cancer Gene Therapy. 12: 359-68. PMID 15678154 DOI: 10.1038/sj.cgt.7700784  0.76
2004 Yamini B, Yu X, Gillespie GY, Kufe DW, Weichselbaum RR. Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma. Cancer Research. 64: 6381-4. PMID 15374943 DOI: 10.1158/0008-5472.CAN-04-2117  0.76
2003 Shah AC, Benos D, Gillespie GY, Markert JM. Oncolytic viruses: clinical applications as vectors for the treatment of malignant gliomas. Journal of Neuro-Oncology. 65: 203-26. PMID 14682372 DOI: 10.1023/B:NEON.0000003651.97832.6c  0.76
2003 Tsai JC, Teng LJ, Chen CT, Hong TM, Goldman CK, Gillespie GY. Protein kinase C mediates induced secretion of vascular endothelial growth factor by human glioma cells. Biochemical and Biophysical Research Communications. 309: 952-60. PMID 13679066 DOI: 10.1016/j.bbrc.2003.08.106  0.76
2003 Safavy A, Bonner JA, Waksal HW, Buchsbaum DJ, Gillespie GY, Khazaeli MB, Arani R, Chen DT, Carpenter M, Raisch KP. Synthesis and biological evaluation of paclitaxel-C225 conjugate as a model for targeted drug delivery. Bioconjugate Chemistry. 14: 302-10. PMID 12643740 DOI: 10.1021/bc020033z  0.76
2002 Blanquicett C, Gillespie GY, Nabors LB, Miller CR, Bharara S, Buchsbaum DJ, Diasio RB, Johnson MR. Induction of thymidine phosphorylase in both irradiated and shielded, contralateral human U87MG glioma xenografts: implications for a dual modality treatment using capecitabine and irradiation. Molecular Cancer Therapeutics. 1: 1139-45. PMID 12481438  0.76
2002 Kaliberov SA, Buchsbaum DJ, Gillespie GY, Curiel DT, Arafat WO, Carpenter M, Stackhouse MA. Adenovirus-mediated transfer of BAX driven by the vascular endothelial growth factor promoter induces apoptosis in lung cancer cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 190-8. PMID 12161185 DOI: 10.1006/mthe.2002.0648  0.76
2002 Cobbs CS, Harkins L, Samanta M, Gillespie GY, Bharara S, King PH, Nabors LB, Cobbs CG, Britt WJ. Human cytomegalovirus infection and expression in human malignant glioma. Cancer Research. 62: 3347-50. PMID 12067971  0.76
2002 Hecker TP, Grammer JR, Gillespie GY, Stewart J, Gladson CL. Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples. Cancer Research. 62: 2699-707. PMID 11980671  0.76
2002 Choi C, Gillespie GY, Van Wagoner NJ, Benveniste EN. Fas engagement increases expression of interleukin-6 in human glioma cells. Journal of Neuro-Oncology. 56: 13-9. PMID 11949822 DOI: 10.1023/A:1014467626314  0.76
2002 Chung SM, Advani SJ, Bradley JD, Kataoka Y, Vashistha K, Yan SY, Markert JM, Gillespie GY, Whitley RJ, Roizman B, Weichselbaum RR. The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma. Gene Therapy. 9: 75-80. PMID 11850725 DOI: 10.1038/sj.gt.3301620  0.76
2002 Miller CR, Williams CR, Buchsbaum DJ, Gillespie GY. Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas. Cancer Research. 62: 773-80. PMID 11830532  0.76
2002 Cassady KA, Gross M, Gillespie GY, Roizman B. Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence. Journal of Virology. 76: 942-9. PMID 11773369  0.76
2001 Debinski W, Slagle-Webb B, Achen MG, Stacker SA, Tulchinsky E, Gillespie GY, Gibo DM. VEGF-D is an X-linked/AP-1 regulated putative onco-angiogen in human glioblastoma multiforme. Molecular Medicine (Cambridge, Mass.). 7: 598-608. PMID 11778649  0.76
2001 Ansardi DC, Porter DC, Jackson CA, Gillespie GY, Morrow CD. RNA replicons derived from poliovirus are directly oncolytic for human tumor cells of diverse origins. Cancer Research. 61: 8470-9. PMID 11731430  0.76
2001 Cobbs CS, Samanta M, Harkins LE, Gillespie GY, Merrick BA, MacMillan-Crow LA. Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: possible functional consequences. Archives of Biochemistry and Biophysics. 394: 167-72. PMID 11594730 DOI: 10.1006/abbi.2001.2540  0.76
2001 Berdiev BK, Mapstone TB, Markert JM, Gillespie GY, Lockhart J, Fuller CM, Benos DJ. pH alterations "reset" Ca2+ sensitivity of brain Na+ channel 2, a degenerin/epithelial Na+ ion channel, in planar lipid bilayers. The Journal of Biological Chemistry. 276: 38755-61. PMID 11514582 DOI: 10.1074/jbc.M107266200  0.76
2001 Choi C, Xu X, Oh JW, Lee SJ, Gillespie GY, Park H, Jo H, Benveniste EN. Fas-induced expression of chemokines in human glioma cells: involvement of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase. Cancer Research. 61: 3084-91. PMID 11306491  0.76
2001 Nabors LB, Gillespie GY, Harkins L, King PH. HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3' untranslated regions of cytokine and angiogenic factor mRNAs. Cancer Research. 61: 2154-61. PMID 11280780  0.76
2001 Markert JM, Fuller CM, Gillespie GY, Bubien JK, McLean LA, Hong RL, Lee K, Gullans SR, Mapstone TB, Benos DJ. Differential gene expression profiling in human brain tumors. Physiological Genomics. 5: 21-33. PMID 11161003  0.76
2000 Debinski W, Slagle B, Gibo DM, Powers SK, Gillespie GY. Expression of a restrictive receptor for interleukin 13 is associated with glial transformation. Journal of Neuro-Oncology. 48: 103-11. PMID 11083073 DOI: 10.1023/A:1006446426611  0.76
2000 Ghant VK, Hiramoto NS, Gillespie GY, Gauthier DK, Hiramoto RN. Immunotherapy of a murine T cell lymphoma localized to the brain. Journal of Neuro-Oncology. 47: 1-10. PMID 10930094 DOI: 10.1023/A:1006475516746  0.76
2000 Markert JM, Medlock MD, Rabkin SD, Gillespie GY, Todo T, Hunter WD, Palmer CA, Feigenbaum F, Tornatore C, Tufaro F, Martuza RL. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Therapy. 7: 867-74. PMID 10845725 DOI: 10.1038/sj.gt.3301205  0.76
2000 Bledsoe AW, Gillespie GY, Morrow CD. Targeted foreign gene expression in spinal cord neurons using poliovirus replicons. Journal of Neurovirology. 6: 95-105. PMID 10822323  0.76
2000 Parker JN, Gillespie GY, Love CE, Randall S, Whitley RJ, Markert JM. Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 97: 2208-13. PMID 10681459 DOI: 10.1073/pnas.040557897  0.76
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