Frank Furnari, Ph.D. - Related publications

Pathology University of California, San Diego, La Jolla, CA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Shi Z, Gao Y, Feng L, Tian W, Dou Z, Liu C, Liu J, Xu Y, Wang Y, Yan J, Wu Q, Li J, Yang L, Zhang Z, Yang J, et al. TR35 Exerts Anti-tumor Effects by Modulating Mitogen-Activated Protein Kinase and STAT3 Signaling in Lung Cancer Cells. Frontiers in Cell and Developmental Biology. 9: 723346. PMID 34760885 DOI: 10.3389/fcell.2021.723346   
2021 Carvalho MI, Raposo TP, Silva-Carvalho R, Pires I, Prada J, Gregório H, Queiroga FL. The Dog as a Model to Study the Tumor Microenvironment. Advances in Experimental Medicine and Biology. 1329: 123-152. PMID 34664237 DOI: 10.1007/978-3-030-73119-9_7   
2021 Butti R, Kumar TVS, Nimma R, Banerjee P, Kundu IG, Kundu GC. Osteopontin Signaling in Shaping Tumor Microenvironment Conducive to Malignant Progression. Advances in Experimental Medicine and Biology. 1329: 419-441. PMID 34664250 DOI: 10.1007/978-3-030-73119-9_20   
2021 Li W, Song P, Zhao M, Gao L, Xie J, You C. BOP1 Used as a Novel Prognostic Marker and Correlated with Tumor Microenvironment in Pan-Cancer. Journal of Oncology. 2021: 3603030. PMID 34603446 DOI: 10.1155/2021/3603030   
2021 Meng Q, Xie S, Gray GK, Dezfulian MH, Li W, Huang L, Akshinthala D, Ferrer E, Conahan C, Perea Del Pino S, Grossman J, Elledge SJ, Hidalgo M, Muthuswamy SK. Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids. Journal For Immunotherapy of Cancer. 9. PMID 34789550 DOI: 10.1136/jitc-2021-003213   
2021 Li R, Song X, Guo Y, Song P, Duan D, Chen ZS. Natural Products: A Promising Therapeutics for Targeting Tumor Angiogenesis. Frontiers in Oncology. 11: 772915. PMID 34746014 DOI: 10.3389/fonc.2021.772915   
2021 Hao N, Zhou Y, Li Y, Zhang H, Wang B, Liu X, Ren Y, He J, Zhou C, Tang X. Clinical Value and Potential Mechanisms of Oxysterol-Binding Protein Like 3 (OSBPL3) in Human Tumors. Frontiers in Molecular Biosciences. 8: 739978. PMID 34738015 DOI: 10.3389/fmolb.2021.739978   
2021 Chen Y, Zhang Z, Henson ES, Cuddihy A, Haigh K, Wang R, Haigh JJ, Gibson SB. Autophagy inhibition by TSSC4 (tumor suppressing subtransferable candidate 4) contributes to sustainable cancer cell growth. Autophagy. 1-23. PMID 34530675 DOI: 10.1080/15548627.2021.1973338   
2021 Shao Q, Wang L, Yuan M, Jin X, Chen Z, Wu C. TIGIT Induces (CD3+) T Cell Dysfunction in Colorectal Cancer by Inhibiting Glucose Metabolism. Frontiers in Immunology. 12: 688961. PMID 34659197 DOI: 10.3389/fimmu.2021.688961   
2021 Jiang M, Chu Y, Yang T, Li W, Zhang Z, Sun H, Liang H, Yang F. Developing a Novel Indium(III) Agent Based on Liposomes to Overcome Cisplatin-Induced Resistance in Breast Cancer by Multitargeting the Tumor Microenvironment Components. Journal of Medicinal Chemistry. PMID 34609868 DOI: 10.1021/acs.jmedchem.1c01068   
2021 Ma F, Vayalil J, Lee G, Wang Y, Peng G. Emerging role of tumor-derived extracellular vesicles in T cell suppression and dysfunction in the tumor microenvironment. Journal For Immunotherapy of Cancer. 9. PMID 34642246 DOI: 10.1136/jitc-2021-003217   
2021 Kumari S, Advani D, Sharma S, Ambasta RK, Kumar P.. Combinatorial therapy in tumor microenvironment: Where do we stand?. 2021 Jul 2; [Epub ahead of print] Review. PubMed PMID: Biochim Biophys Acta Rev Cancer.. 1876: 188585. PMID 34224836 DOI: doi: 10.1016/j.bbcan.2021.188585.   
2021 Barthel L, Hadamitzky M, Dammann P, Schedlowski M, Sure U, Thakur BK, Hetze S. Glioma: molecular signature and crossroads with tumor microenvironment. Cancer Metastasis Reviews. PMID 34687436 DOI: 10.1007/s10555-021-09997-9   
2021 Varney SD, Wu L, Longmate WM, DiPersio CM, Van De Water L. Loss of integrin α9β1 on tumor keratinocytes enhances the stromal vasculature and growth of cutaneous tumors. The Journal of Investigative Dermatology. PMID 34843681 DOI: 10.1016/j.jid.2021.11.020   
2021 Cheng L, Creasy T, Pilataxi F, Greenlees L, Vence L, Sridhar S, Streicher K. Effects of combination treatment with durvalumab plus tremelimumab on the tumor microenvironment in non-small-cell lung carcinoma. Cancer Immunology, Immunotherapy : Cii. PMID 34623465 DOI: 10.1007/s00262-021-03065-5   
2021 Yan M, Hu J, Ping Y, Xu L, Liao G, Jiang Z, Pang B, Sun S, Zhang Y, Xiao Y, Li X. Single-Cell Transcriptomic Analysis Reveals a Tumor-Reactive T Cell Signature Associated With Clinical Outcome and Immunotherapy Response In Melanoma. Frontiers in Immunology. 12: 758288. PMID 34804045 DOI: 10.3389/fimmu.2021.758288   
2021 He Q, Jamalpour M, Bergquist E, Anderson RL, Gustafsson K, Welsh M. Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in -Deficient Endothelial Cells Increases Tumor Lung Metastasis. International Journal of Molecular Sciences. 22. PMID 34768912 DOI: 10.3390/ijms222111478   
2021 Jesser EA, Brady NJ, Huggins DN, Witschen PM, O'Connor CH, Schwertfeger KL. STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment. Breast Cancer Research : Bcr. 23: 104. PMID 34743736 DOI: 10.1186/s13058-021-01481-0   
2021 Zalles M, Smith N, Saunders D, Guzman M, Lerner M, Fung KM, Babu A, Battiste J, Chung J, Hwang K, Jin J, Towner RA. ELTD1 as a multi-focal target for malignant gliomas: preclinical studies. Neuro-Oncology Advances. 3: vdab132. PMID 34704036 DOI: 10.1093/noajnl/vdab132   
2021 Chen Q, Li Y, Gao W, Chen L, Xu W, Zhu X. Exosome-Mediated Crosstalk Between Tumor and Tumor-Associated Macrophages. Frontiers in Molecular Biosciences. 8: 764222. PMID 34722637 DOI: 10.3389/fmolb.2021.764222   
2021 Zong S, Dai W, Guo X, Wang K. LncRNA-SNHG1 promotes macrophage M2-like polarization and contributes to breast cancer growth and metastasis. Aging. 13: 23169-23181. PMID 34618681 DOI: 10.18632/aging.203609   
2021 Xu Z, Hu K, Bailey P, Springfeld C, Roth S, Kurilov R, Brors B, Gress T, Buchholz M, An J, Wei K, Peccerella T, Büchler MW, Hackert T, Neoptolemos JP. Clinical Impact of Molecular Subtyping of Pancreatic Cancer. Frontiers in Cell and Developmental Biology. 9: 743908. PMID 34805152 DOI: 10.3389/fcell.2021.743908   
2021 Pai FC, Huang HW, Tsai YL, Tsai WC, Cheng YC, Chang HH, Chen Y. Inhibition of FABP6 Reduces Tumor Cell Invasion and Angiogenesis through the Decrease in MMP-2 and VEGF in Human Glioblastoma Cells. Cells. 10. PMID 34685761 DOI: 10.3390/cells10102782   
2021 Zhou R, Feng Y, Ye J, Han Z, Liang Y, Chen Q, Xu X, Huang Y, Jia Z, Zhong W. Prediction of Biochemical Recurrence-Free Survival of Prostate Cancer Patients Leveraging Multiple Gene Expression Profiles in Tumor Microenvironment. Frontiers in Oncology. 11: 632571. PMID 34631510 DOI: 10.3389/fonc.2021.632571   
2021 Shih HJ, Chang HF, Chen CL, Torng PL. Differential expression of hypoxia-inducible factors related to the invasiveness of epithelial ovarian cancer. Scientific Reports. 11: 22925. PMID 34824343 DOI: 10.1038/s41598-021-02400-1   
2021 Sun X, Chen Q, Zhang L, Chen J, Zhang X. Exploration of prognostic biomarkers and therapeutic targets in the microenvironment of bladder cancer based on CXC chemokines. Mathematical Biosciences and Engineering : Mbe. 18: 6262-6287. PMID 34517533 DOI: 10.3934/mbe.2021313   
2021 He C, Sheng L, Pan D, Jiang S, Ding L, Ma X, Liu Y, Jia D. Single-Cell Transcriptomic Analysis Revealed a Critical Role of SPP1/CD44-Mediated Crosstalk Between Macrophages and Cancer Cells in Glioma. Frontiers in Cell and Developmental Biology. 9: 779319. PMID 34805184 DOI: 10.3389/fcell.2021.779319   
2021 Kim SY, Johns SC, Gupta P, Varki N, Fuster MM. Targeting glycan sulfation in a CD11c+ myeloid population inhibits early KRAS-mutant lung neoplasia. Neoplasia (New York, N.Y.). 23: 1137-1143. PMID 34715561 DOI: 10.1016/j.neo.2021.09.008   
2021 Castro J, Tornillo G, Ceada G, Ramos-Neble B, Bravo M, Ribó M, Vilanova M, Smalley MJ, Benito A. A Nuclear-Directed Ribonuclease Variant Targets Cancer Stem Cells and Inhibits Migration and Invasion of Breast Cancer Cells. Cancers. 13. PMID 34503160 DOI: 10.3390/cancers13174350   
2021 Chen X, Song J, Wang X, Sun D, Liu Y, Jiang Y. LncRNA LINC00460: Function and mechanism in human cancer. Thoracic Cancer. PMID 34821482 DOI: 10.1111/1759-7714.14238   
2021 Zhao G, Shi X, Sun Z, Zhao P, Lu Z. PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway. Acta Biochimica Et Biophysica Sinica. PMID 34718369 DOI: 10.1093/abbs/gmab143   
2021 Yao J, Yang J, Yang Z, Wang XP, Yang T, Ji B, Zhang ZY. FBXW11 contributes to stem-cell-like features and liver metastasis through regulating HIC1-mediated SIRT1 transcription in colorectal cancer. Cell Death & Disease. 12: 930. PMID 34642302 DOI: 10.1038/s41419-021-04185-7   
2021 Yueh PF, Lee YH, Chiang IT, Chen WT, Lan KL, Chen CH, Hsu FT. Suppression of EGFR/PKC-δ/NF-κB Signaling Associated With Imipramine-Inhibited Progression of Non-Small Cell Lung Cancer. Frontiers in Oncology. 11: 735183. PMID 34765548 DOI: 10.3389/fonc.2021.735183   
2021 Zhuang Y, Ma Y, Yan S, Zhao B, Wu S, Zhang Q, Huang X, Zhao H, Zhao C, Liu Z, Yang L. Cyy260, a novel small molecule inhibitor, suppresses non-small cell lung cancer cell growth via JAK2/STAT3 pathway. American Journal of Cancer Research. 11: 4241-4258. PMID 34659885   
2021 Pachva MC, Lai H, Jia A, Rouleau M, Sorensen PH. Extracellular Vesicles in Reprogramming of the Ewing Sarcoma Tumor Microenvironment. Frontiers in Cell and Developmental Biology. 9: 726205. PMID 34604225 DOI: 10.3389/fcell.2021.726205   
2021 McNulty SN, Schwetye KE, Ferguson C, Storer CE, Ansstas G, Kim AH, Gutmann DH, Rubin JB, Head RD, Dahiya S. BRAF mutations may identify a clinically distinct subset of glioblastoma. Scientific Reports. 11: 19999. PMID 34625582 DOI: 10.1038/s41598-021-99278-w   
2021 Tan T, Li J, Luo R, Wang R, Yin L, Liu M, Zeng Y, Zeng Z, Xie T. Recent Advances in Understanding the Mechanisms of Elemene in Reversing Drug Resistance in Tumor Cells: A Review. Molecules (Basel, Switzerland). 26. PMID 34641334 DOI: 10.3390/molecules26195792   
2021 Gong L, Li Y, Cui K, Chen Y, Hong H, Li J, Li D, Yin Y, Wu Z, Huang Z. Nanobody-Engineered Natural Killer Cell Conjugates for Solid Tumor Adoptive Immunotherapy. Small (Weinheim An Der Bergstrasse, Germany). 17: e2103463. PMID 34761524 DOI: 10.1002/smll.202103463   
2021 Bhat SM, Badiger VA, Vasishta S, Chakraborty J, Prasad S, Ghosh S, Joshi MB. 3D tumor angiogenesis models: recent advances and challenges. Journal of Cancer Research and Clinical Oncology. PMID 34613483 DOI: 10.1007/s00432-021-03814-0   
2021 Guo ZS, Qu Z. PDLIM2: Signaling pathways and functions in cancer suppression and host immunity. Biochimica Et Biophysica Acta. Reviews On Cancer. 1876: 188630. PMID 34571051 DOI: 10.1016/j.bbcan.2021.188630   
2021 Chen GT, Tifrea DF, Murad R, Habowski AN, Lyou Y, Duong MR, Hosohama L, Mortazavi A, Edwards RA, Waterman ML. Disruption of beta-catenin dependent Wnt signaling in colon cancer cells remodels the microenvironment to promote tumor invasion. Molecular Cancer Research : McR. PMID 34799404 DOI: 10.1158/1541-7786.MCR-21-0349   
2021 Zou Y, Huang L, Sun S, Yue F, Li Z, Ma Y, Ma H. Choline Kinase Alpha Promoted Glioma Development by Activating PI3K/AKT Signaling Pathway. Cancer Biotherapy & Radiopharmaceuticals. PMID 34788108 DOI: 10.1089/cbr.2021.0294   
2021 Sakai H, Kawakami H, Teramura T, Onodera Y, Somers E, Furuuchi K, Uenaka T, Kato R, Nakagawa K. Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer. Clinical and Translational Medicine. 11: e454. PMID 34185411 DOI: 10.1002/ctm2.454   
2021 Miao D, Wang Y, Jia Y, Tong J, Jiang S, Liu L. ZRANB1 enhances stem-cell-like features and accelerates tumor progression by regulating Sox9-mediated USP22/Wnt/β-catenin pathway in colorectal cancer. Cellular Signalling. 110200. PMID 34798260 DOI: 10.1016/j.cellsig.2021.110200   
2021 Andersson A, Larsson L, Stenbeck L, Salmén F, Ehinger A, Wu SZ, Al-Eryani G, Roden D, Swarbrick A, Borg Å, Frisén J, Engblom C, Lundeberg J. Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions. Nature Communications. 12: 6012. PMID 34650042 DOI: 10.1038/s41467-021-26271-2   
2021 Mehra S, Deshpande N, Nagathihalli N. Targeting PI3K Pathway in Pancreatic Ductal Adenocarcinoma: Rationale and Progress. Cancers. 13. PMID 34503244 DOI: 10.3390/cancers13174434   
2021 Xia M, Cao H, Zheng J, Yao Y, Xu F, Lu G, Ma Y, Zhou J. A novel stilbene derivative (GMQ3) suppressed proliferation and induced apoptosis in lung cancer via the p38-MAPK/SIRT1 pathway. Biochemical Pharmacology. 193: 114808. PMID 34678220 DOI: 10.1016/j.bcp.2021.114808   
2021 Araújo TG, Mota STS, Ferreira HSV, Ribeiro MA, Goulart LR, Vecchi L. Annexin A1 as a Regulator of Immune Response in Cancer. Cells. 10. PMID 34571894 DOI: 10.3390/cells10092245   
2021 Singh K, Hotchkiss KM, Patel KK, Wilkinson DS, Mohan AA, Cook SL, Sampson JH. Enhancing T Cell Chemotaxis and Infiltration in Glioblastoma. Cancers. 13. PMID 34771532 DOI: 10.3390/cancers13215367   
2021 Lai J, Li J, Gniadecki R, Lai R. Gene Expression Profiling of Mycosis Fungoides in Early and Tumor Stage-A Proof-of-Concept Study Using Laser Capture/Single Cell Microdissection and NanoString Analysis. Cells. 10. PMID 34831413 DOI: 10.3390/cells10113190