Forest M. White, Ph.D. - Related publications

Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
protein phosphorylation, signal transduction cascades
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Molina E, Hong L, Chefetz I. NUAK Kinases: Brain-Ovary Axis. Cells. 10. PMID 34685740 DOI: 10.3390/cells10102760   
2021 Padros J, Chatel G, Caron M. Time-resolved Förster Resonance Energy Transfer Assays for Measurement of Endogenous Phosphorylated STAT Proteins in Human Cells. Journal of Visualized Experiments : Jove. PMID 34570089 DOI: 10.3791/62915   
2021 Prasher P, Sharma M, Chan Y, Singh SK, Anand K, Dureja H, Jha NK, Gupta G, Zacconi F, Chellappan DK, Dua K. Recent Trends in rationally designed molecules as kinase inhibitors. Current Medicinal Chemistry. PMID 34766883 DOI: 10.2174/0929867328666211111161811   
2021 Mathien S, Tesnière C, Meloche S. Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential. Pharmacological Reviews. 73: 263-296. PMID 34732541 DOI: 10.1124/pharmrev.120.000170   
2021 Guo X, He H, Yu J, Shi S. PKSPS: a novel method for predicting kinase of specific phosphorylation sites based on maximum weighted bipartite matching algorithm and phosphorylation sequence enrichment analysis. Briefings in Bioinformatics. PMID 34661630 DOI: 10.1093/bib/bbab436   
2021 Smith TG, Uzozie AC, Chen S, Lange PF. Robust unsupervised deconvolution of linear motifs characterizes 68 protein modifications at proteome scale. Scientific Reports. 11: 22490. PMID 34795380 DOI: 10.1038/s41598-021-01971-3   
2021 Lin ZY, Yun QZ, Wu L, Zhang TW, Yao TZ. Pharmacological basis and new insights of deguelin concerning its anticancer effects. Pharmacological Research. 105935. PMID 34644595 DOI: 10.1016/j.phrs.2021.105935   
2021 Chen PH, Hu Z, An E, Okeke I, Zheng S, Luo X, Gong A, Jaime-Figueroa S, Crews CM. Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs). Acs Chemical Biology. PMID 34780684 DOI: 10.1021/acschembio.1c00693   
2021 Li Y, Liu Y, Huang X, Ren J. Analysis of protein phosphorylation combining capillary electrophoresis with ATP analogue labelling technique. Electrophoresis. PMID 34783369 DOI: 10.1002/elps.202100251   
2021 Fan Y, Ren X, Wang Y, Xu E, Wang S, Ge R, Liu Y. Metformin inhibits the proliferation of canine mammary gland tumor cells through the AMPK/AKT/mTOR signaling pathway . Oncology Letters. 22: 852. PMID 34733370 DOI: 10.3892/ol.2021.13113   
2021 Zhao M, Finlay D, Kwong E, Liddington R, Viollet B, Sasaoka N, Vuori K. Cell adhesion suppresses autophagy via Src/FAK-mediated phosphorylation and inhibition of AMPK. Cellular Signalling. 89: 110170. PMID 34673141 DOI: 10.1016/j.cellsig.2021.110170   
2021 Zhu DW, Yu Q, Sun JJ, Shen YH. Evaluating the Therapeutic Mechanisms of Selected Active Compounds in Thunb. in Pulmonary Fibrosis Network Pharmacology Analysis. Frontiers in Pharmacology. 12: 733618. PMID 34658873 DOI: 10.3389/fphar.2021.733618   
2021 Liao Z, Zhang C, Ding L, Moyers JS, Tang JX, Beals JM. Comprehensive Insulin Receptor Phosphorylation Dynamics Profiled by Mass Spectrometry. The Febs Journal. PMID 34826178 DOI: 10.1111/febs.16299   
2021 Reusch B, Bartram MP, Dafinger C, Palacio-Escat N, Wenzel A, Fenton RA, Saez-Rodriguez J, Schermer B, Benzing T, Altmüller J, Beck BB, Rinschen MM. MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells. Journal of Proteomics. 104424. PMID 34775100 DOI: 10.1016/j.jprot.2021.104424   
2021 Iannetta AA, Minton NE, Uitenbroek AA, Little JL, Stanton CR, Kristich CJ, Hicks LM. IreK-Mediated, Cell Wall-Protective Phosphorylation in . Journal of Proteome Research. 20: 5131-5144. PMID 34672600 DOI: 10.1021/acs.jproteome.1c00635   
2021 Agnihotri SK, Kar P, Singh M, Pant G, Mitra K, Bhatt MLB, Sachdev M. Modulation of protein phosphatase 1 gamma 2 during cell division of cervical cancer HeLa cells. Contemporary Oncology (Poznan, Poland). 25: 125-132. PMID 34667439 DOI: 10.5114/wo.2021.107745   
2021 Zhang Z, Ran Y, Xu L, Pan Z, Xie Y. High-dose dexamethasone injection disordered metabolism and multiple protein kinases expression in the mouse kidney. Bioscience Reports. PMID 34735568 DOI: 10.1042/BSR20211847   
2021 Hollenstein DM, Gérecová G, Romanov N, Ferrari J, Veis J, Janschitz M, Beyer R, Schüller C, Ogris E, Hartl M, Ammerer G, Reiter W. A phosphatase-centric mechanism drives stress signaling response. Embo Reports. e52476. PMID 34558777 DOI: 10.15252/embr.202152476   
2021 Xie Y, Mu C, Kazybay B, Sun Q, Kutzhanova A, Nazarbek G, Xu N, Nurtay L, Wang Q, Amin A, Li X. Network pharmacology and experimental investigation of extract targeted kinase with herbzyme activity for potent drug delivery. Drug Delivery. 28: 2187-2197. PMID 34662244 DOI: 10.1080/10717544.2021.1977422   
2021 Geng Q, Liu B, Zhao PC, Xiong YB, Li L, Yi JF, Lyu C. [Molecular mechanism of Fagopyri Dibotryis Rhizoma in treatment of acute lung injury based on network pharmacology and in vitro experiments]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 4816-4823. PMID 34581093 DOI: 10.19540/j.cnki.cjcmm.20210524.401   
2021 Ramadan M, A M M Elshaier Y, Aly AA, Abdel-Aziz M, Fathy HM, Brown AB, Pridgen JR, Dalby KN, Kaoud TS. Development of 2'-aminospiro [pyrano[3,2-c]quinoline]-3'-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation. Bioorganic Chemistry. 116: 105344. PMID 34598088 DOI: 10.1016/j.bioorg.2021.105344   
2021 Lee CJ, Lee GE, An HJ, Cho ES, Chen W, Lee JY, Kang HC, Lee HS, Cho YY. F-box Protein βTrCP1 Is a Substrate of Extracellular Signal-regulated Kinase 2. Journal of Cancer Prevention. 26: 174-182. PMID 34703820 DOI: 10.15430/JCP.2021.26.3.174   
2021 Pei H, Wu S, Zheng L, Wang H, Zhang X. Identification of the active compounds and their mechanisms of medicinal and edible Shanzha based on network pharmacology and molecular docking. Journal of Food Biochemistry. e14020. PMID 34825377 DOI: 10.1111/jfbc.14020   
2021 Clark NM, Nolan TM, Wang P, Song G, Montes C, Valentine CT, Guo H, Sozzani R, Yin Y, Walley JW. Integrated omics networks reveal the temporal signaling events of brassinosteroid response in Arabidopsis. Nature Communications. 12: 5858. PMID 34615886 DOI: 10.1038/s41467-021-26165-3   
2021 Nam HK, Jeong SR, Pyo MC, Ha SK, Nam MH, Lee KW. Methylglyoxal-Derived Advanced Glycation End Products (AGE4) Promote Cell Proliferation and Survival in Renal Cell Carcinoma Cells through the RAGE/Akt/ERK Signaling Pathways. Biological & Pharmaceutical Bulletin. 44: 1697-1706. PMID 34719646 DOI: 10.1248/bpb.b21-00382   
2021 Ortega MA, Fraile-Martínez O, García-Montero C, Ruiz-Grande F, Barrena S, Montoya H, Pekarek L, Zoullas S, Alvarez-Mon MA, Sainz F, Asúnsolo A, Acero J, Álvarez-Mon M, Buján J, García-Honduvilla N, et al. Chronic venous disease patients show increased IRS-4 expression in the great saphenous vein wall. The Journal of International Medical Research. 49: 3000605211041275. PMID 34590920 DOI: 10.1177/03000605211041275   
2021 Bumpus TW, Huang S, Tei R, Baskin JM. Click chemistry-enabled CRISPR screening reveals GSK3 as a regulator of PLD signaling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34810254 DOI: 10.1073/pnas.2025265118   
2021 Sahin KB, Shah ET, Ferguson GP, Molloy C, Kalita-de Croft P, Hayes SA, Hudson A, Colvin E, Kamitakahara H, Harvie R, Hasovits C, Khan T, Duijf PHG, Howell VM, He Y, et al. Elevating CDCA3 Levels Enhances Tyrosine Kinase Inhibitor Sensitivity in TKI-Resistant EGFR Mutant Non-Small-Cell Lung Cancer. Cancers. 13. PMID 34572879 DOI: 10.3390/cancers13184651   
2021 Wang W, Dai Z, Li J, Ouyang J, Li T, Zeng B, Kang L, Jia K, Xi Z, Jia W. A Method for Assaying of Protein Kinase Activity In Vivo and Its Use in Studies of Signal Transduction in Strawberry Fruit Ripening. International Journal of Molecular Sciences. 22. PMID 34638834 DOI: 10.3390/ijms221910495   
2021 Liu X, Fields R, Schweppe DK, Paulo JA. Strategies for mass spectrometry-based phosphoproteomics using isobaric tagging. Expert Review of Proteomics. 1-13. PMID 34652972 DOI: 10.1080/14789450.2021.1994390   
2021 Huang LC, Taujale R, Gravel N, Venkat A, Yeung W, Byrne DP, Eyers PA, Kannan N. KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases. Bmc Bioinformatics. 22: 446. PMID 34537014 DOI: 10.1186/s12859-021-04358-3   
2021 Zhang S, Chen H, Li C, Chen B, Gong H, Zhao Y, Qi R. Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets. Frontiers in Pharmacology. 12: 746107. PMID 34646142 DOI: 10.3389/fphar.2021.746107   
2021 Xu P, Zhao Y, Yu T, Yu Y, Ni X, Wang H, Sun L, Han P, Wang L, Sun T, Liu X, Zhou H, Peng J, Hou M, Hou Y, et al. Atorvastatin restores imbalance of cluster of differentiation 4 (CD4) T cells in immune thrombocytopenia in vivo and in vitro. British Journal of Haematology. PMID 34825359 DOI: 10.1111/bjh.17938   
2021 Jamal S, Ali W, Nagpal P, Grover A, Grover S. Predicting phosphorylation sites using machine learning by integrating the sequence, structure, and functional information of proteins. Journal of Translational Medicine. 19: 218. PMID 34030700 DOI: 10.1186/s12967-021-02851-0   
2021 Mysore VP, Zhou ZW, Ambrogio C, Li L, Kapp JN, Lu C, Wang Q, Tucker MR, Okoro JJ, Nagy-Davidescu G, Bai X, Plückthun A, Jänne PA, Westover KD, Shan Y, et al. A structural model of a Ras-Raf signalosome. Nature Structural & Molecular Biology. 28: 847-857. PMID 34625747 DOI: 10.1038/s41594-021-00667-6   
2021 Xu X, Yin S, Ren Y, Hu C, Zhang A, Lin Y. Proteomics analysis reveals the correlation of programmed ROS-autophagy loop and dysregulated G1/S checkpoint with imatinib resistance in chronic myeloid leukemia cells. Proteomics. e2100094. PMID 34564948 DOI: 10.1002/pmic.202100094   
2021 Brown SL, Ren Y, Suter DM, Mattoo S. A Co-purification Method for Efficient Production and Src Kinase-mediated Phosphorylation of Cortactin. Bio-Protocol. 11: e4158. PMID 34692908 DOI: 10.21769/BioProtoc.4158   
2021 Chiurillo MA, Jensen BC, Docampo R. Drug Target Validation of the Protein Kinase Essential for Proliferation, Host Cell Invasion, and Intracellular Replication of the Human Pathogen Trypanosoma cruzi. Microbiology Spectrum. e0073821. PMID 34585973 DOI: 10.1128/Spectrum.00738-21   
2021 Diehl JN, Klomp JE, Snare KR, Hibshman PS, Blake DR, Kaiser ZD, Gilbert TSK, Baldelli E, Pierobon M, Papke B, Yang R, Hodge RG, Rashid NU, Petricoin EF, Herring LE, et al. The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer. The Journal of Biological Chemistry. 101335. PMID 34688654 DOI: 10.1016/j.jbc.2021.101335   
2021 Korkmaz R, Yüksek V, Dede S. The Effects of Sodium Fluoride (NaF) Treatment on the PI3K/Akt Signal Pathway in NRK-52E Cells. Biological Trace Element Research. PMID 34569011 DOI: 10.1007/s12011-021-02927-4   
2021 Wan Y, Wang J, Xu JF, Tang F, Chen L, Tan YZ, Rao CL, Ao H, Peng C. and its ginsenosides: potential candidates for the prevention and treatment of chemotherapy-induced side effects. Journal of Ginseng Research. 45: 617-630. PMID 34764717 DOI: 10.1016/j.jgr.2021.03.001   
2021 Mathis CL, Barrios AM. Histidine phosphorylation in metalloprotein binding sites. Journal of Inorganic Biochemistry. 225: 111606. PMID 34555600 DOI: 10.1016/j.jinorgbio.2021.111606   
2021 Biswas P, Dey D, Rahman A, Islam MA, Susmi TF, Kaium MA, Hasan MN, Rahman MDH, Mahmud S, Saleh MA, Paul P, Rahman MR, Al Saber M, Song H, Rahman MA, et al. Analysis of SYK Gene as a Prognostic Biomarker and Suggested Potential Bioactive Phytochemicals as an Alternative Therapeutic Option for Colorectal Cancer: An In-Silico Pharmaco-Informatics Investigation. Journal of Personalized Medicine. 11. PMID 34575665 DOI: 10.3390/jpm11090888   
2021 Yuan C, Chen G, Jing C, Liu M, Liang B, Gong G, Yu M. Eriocitrin, a dietary flavonoid suppressed cell proliferation, induced apoptosis through modulation of JAK2/STAT3 and JNK/p38 MAPKs signaling pathway in MCF-7 cells. Journal of Biochemical and Molecular Toxicology. e22943. PMID 34724282 DOI: 10.1002/jbt.22943   
2021 Zhao L, Yan J, Xiang Y, Sun Y, Zhang A. Transcription Factor Phosphorylated by Functioning in ABA-Induced Antioxidant Defense and Enhance Drought Tolerance in Maize. Biology. 10. PMID 34571770 DOI: 10.3390/biology10090893   
2021 M Gagné L, Morin N, Lavoie N, Bisson N, Lambert JP, Mallette FA, Huot MÉ. Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling. The Journal of Biological Chemistry. 297: 101291. PMID 34634301 DOI: 10.1016/j.jbc.2021.101291   
2021 Sabbah M, Najem A, Krayem M, Awada A, Journe F, Ghanem GE. RTK Inhibitors in Melanoma: From Bench to Bedside. Cancers. 13. PMID 33918490 DOI: 10.3390/cancers13071685   
2021 Roffey SE, Litchfield DW. CK2 Regulation: Perspectives in 2021. Biomedicines. 9. PMID 34680478 DOI: 10.3390/biomedicines9101361   
2021 Zhang X, Xu H, Bi X, Hou G, Liu A, Zhao Y, Wang G, Cao X. Src acts as the target of matrine to inhibit the proliferation of cancer cells by regulating phosphorylation signaling pathways. Cell Death & Disease. 12: 931. PMID 34642304 DOI: 10.1038/s41419-021-04221-6   
2021 Blaustein M, Piegari E, Martínez Calejman C, Vila A, Amante A, Manese MV, Zeida A, Abrami L, Veggetti M, Guertin DA, van der Goot FG, Corvi MM, Colman-Lerner A. Akt Is S-Palmitoylated: A New Layer of Regulation for Akt. Frontiers in Cell and Developmental Biology. 9: 626404. PMID 33659252 DOI: 10.3389/fcell.2021.626404