Shom Goel, M.D., Ph.D. - Related publications

Cancer Biology Dana-Farber Cancer Institute, Boston, MA, United States 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Yim SY, Lee JS. An Overview of the Genomic Characterization of Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma. 8: 1077-1088. PMID 34522690 DOI: 10.2147/JHC.S270533   
2021 Liu J, Tian Z, Liu T, Wen D, Ma Z, Liu Y, Zhu J. CHSY1 is upregulated and acts as tumor promotor in gastric cancer through regulating cell proliferation, apoptosis, and migration. Cell Cycle (Georgetown, Tex.). 1-14. PMID 34412565 DOI: 10.1080/15384101.2021.1963553   
2021 Zou J, Yang X, Duan J, Wang J, Yang Z, Luo D, Liu L, Chen J, Nie J. A Case Report of Targeted Therapy with Anlotinib in a Patient with Advanced Breast Metaplastic Carcinoma. Oncotargets and Therapy. 14: 4599-4607. PMID 34475766 DOI: 10.2147/OTT.S318645   
2021 Lebok P, Schütt K, Kluth M, Witzel I, Wölber L, Paluchowski P, Terracciano L, Wilke C, Heilenkötter U, Müller V, Schmalfeldt B, Simon R, Sauter G, Von Leffern I, Krech T, et al. High mitochondrial content is associated with breast cancer aggressiveness. Molecular and Clinical Oncology. 15: 203. PMID 34462659 DOI: 10.3892/mco.2021.2365   
2021 Lawal B, Tseng SH, Olugbodi JO, Iamsaard S, Ilesanmi OB, Mahmoud MH, Ahmed SH, Batiha GE, Wu ATH. Pan-Cancer Analysis of Immune Complement Signature C3/C5/C3AR1/C5AR1 in Association with Tumor Immune Evasion and Therapy Resistance. Cancers. 13. PMID 34439277 DOI: 10.3390/cancers13164124   
2021 Wu SY, Lin KC, Lawal B, Wu ATH, Wu CZ. MXD3 as an onco-immunological biomarker encompassing the tumor microenvironment, disease staging, prognoses, and therapeutic responses in multiple cancer types. Computational and Structural Biotechnology Journal. 19: 4970-4983. PMID 34584637 DOI: 10.1016/j.csbj.2021.08.047   
2021 Gao R, Zhao S, Aishanjiang K, Cai H, Wei T, Zhang Y, Liu Z, Zhou J, Han B, Wang J, Ding H, Liu Y, Xu X, Yu Z, Gu J. Deep learning for differential diagnosis of malignant hepatic tumors based on multi-phase contrast-enhanced CT and clinical data. Journal of Hematology & Oncology. 14: 154. PMID 34565412 DOI: 10.1186/s13045-021-01167-2   
2021 Melo CM, Vidotto T, Chaves LP, Lautert-Dutra W, Reis RBD, Squire JA. The Role of Somatic Mutations on the Immune Response of the Tumor Microenvironment in Prostate Cancer. International Journal of Molecular Sciences. 22. PMID 34502458 DOI: 10.3390/ijms22179550   
2021 Yuan C, Zhao X, Wangmo D, Alshareef D, Gates TJ, Subramanian S. Tumor models to assess immune response and tumor-microbiome interactions in colorectal cancer. Pharmacology & Therapeutics. 107981. PMID 34480964 DOI: 10.1016/j.pharmthera.2021.107981   
2021 Talwelkar SS, Mäyränpää MI, Søraas L, Potdar S, Bao J, Hemmes A, Linnavirta N, Lømo J, Räsänen J, Knuuttila A, Wennerberg K, Verschuren EW. Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments. Cell Reports. Medicine. 2: 100373. PMID 34467250 DOI: 10.1016/j.xcrm.2021.100373   
2021 Chen J, Mai H, Chen H, Zhou B, Hou J, Jiang DK. Pan-Cancer Analysis Identified as a Potential Biomarker for Multiple Tumor Types. Frontiers in Molecular Biosciences. 8: 693651. PMID 34490347 DOI: 10.3389/fmolb.2021.693651   
2021 Wolf SP, Wen FT, Schreiber H. Criteria to make animal studies more relevant to treating human cancer. Current Opinion in Immunology. 74: 25-31. PMID 34619458 DOI: 10.1016/j.coi.2021.09.002   
2021 Castro J, Tornillo G, Ceada G, Ramos-Neble B, Bravo M, Ribó M, Vilanova M, Smalley MJ, Benito A. A Nuclear-Directed Ribonuclease Variant Targets Cancer Stem Cells and Inhibits Migration and Invasion of Breast Cancer Cells. Cancers. 13. PMID 34503160 DOI: 10.3390/cancers13174350   
2021 Aryal M, Porter T. Emerging Therapeutic Strategies for Brain Tumors. Neuromolecular Medicine. PMID 34406634 DOI: 10.1007/s12017-021-08681-z   
2021 Cheng L, Creasy T, Pilataxi F, Greenlees L, Vence L, Sridhar S, Streicher K. Effects of combination treatment with durvalumab plus tremelimumab on the tumor microenvironment in non-small-cell lung carcinoma. Cancer Immunology, Immunotherapy : Cii. PMID 34623465 DOI: 10.1007/s00262-021-03065-5   
2021 Brägelmann J, Lorenz C, Borchmann S, Nishii K, Wegner J, Meder L, Ostendorp J, Ast DF, Heimsoeth A, Nakasuka T, Hirabae A, Okawa S, Dammert MA, Plenker D, Klein S, et al. MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nature Communications. 12: 5505. PMID 34535668 DOI: 10.1038/s41467-021-25728-8   
2021 Liu X, Fang J, Huang S, Wu X, Xie X, Wang J, Liu F, Zhang M, Peng Z, Hu N. Tumor-on-a-chip: from bioinspired design to biomedical application. Microsystems & Nanoengineering. 7: 50. PMID 34567763 DOI: 10.1038/s41378-021-00277-8   
2021 Meng B, Strawbridge RR, Tichauer K, Samkoe KS, Davis SC. Monitoring cancer cell surface receptor expression during anti-angiogenesis therapy in vivo. Proceedings of Spie--the International Society For Optical Engineering. 11625. PMID 34446980   
2021 Wang W, Yin Q, Guo S, Wang J. contributes toward the carcinogenesis of liver cancer and regulates PI3K/Akt/mTOR signaling. Experimental and Therapeutic Medicine. 22: 1053. PMID 34434267 DOI: 10.3892/etm.2021.10487   
2021 He F, Xia Y, Ling X. Diagnosis and Individualized Treatment of Three Primary Malignant Tumors: A Case Report. Breast Cancer (Dove Medical Press). 13: 519-527. PMID 34526817 DOI: 10.2147/BCTT.S321390   
2021 Li J, Xie J, Wu D, Chen L, Gong Z, Wu R, Hu Y, Zhao J, Xu Y. A pan-cancer analysis revealed the role of the SLC16 family in cancer. Channels (Austin, Tex.). 15: 528-540. PMID 34424811 DOI: 10.1080/19336950.2021.1965422   
2021 Ionkina AA, Balderrama-Gutierrez G, Ibanez KJ, Phan SHD, Cortez AN, Mortazavi A, Prescher JA. Transcriptome analysis of heterogeneity in mouse model of metastatic breast cancer. Breast Cancer Research : Bcr. 23: 93. PMID 34579762 DOI: 10.1186/s13058-021-01468-x   
2021 Wong C, Li B. AutoCAT: Automated cancer-associated TCRs discovery from TCR-seq data. Bioinformatics (Oxford, England). PMID 34529039 DOI: 10.1093/bioinformatics/btab661   
2021 Hart PC, Bajwa P, Kenny HA. Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity. Advances in Experimental Medicine and Biology. 1330: 75-94. PMID 34339031 DOI: 10.1007/978-3-030-73359-9_5   
2021 Liguori NR, Lee Y, Borges W, Zhou L, Azzoli C, El-Deiry WS. Absence of Biomarker-Driven Treatment Options in Small Cell Lung Cancer, and Selected Preclinical Candidates for Next Generation Combination Therapies. Frontiers in Pharmacology. 12: 747180. PMID 34531756 DOI: 10.3389/fphar.2021.747180   
2021 Karin M, Shalapour S. Regulation of antitumor immunity by inflammation-induced epigenetic alterations. Cellular & Molecular Immunology. PMID 34465885 DOI: 10.1038/s41423-021-00756-y   
2021 Lu T, Wei L, Huang X, Li Y, Li G, Qin Q, Pan M, Tang B, Pan X, Wei M, Nong Z, Meng F, Li X. A potentially valuable nano graphene oxide/USPIO tumor diagnosis and treatment system. Materials Science & Engineering. C, Materials For Biological Applications. 128: 112293. PMID 34474844 DOI: 10.1016/j.msec.2021.112293   
2021 Kwantwi LB, Wang S, Zhang W, Peng W, Cai Z, Sheng Y, Xiao H, Wang X, Wu Q. Tumor-associated neutrophils activated by tumor-derived CCL20 (C-C motif chemokine ligand 20) promote T cell immunosuppression via programmed death-ligand 1 (PD-L1) in breast cancer. Bioengineered. 12: 6996-7006. PMID 34519637 DOI: 10.1080/21655979.2021.1977102   
2021 Chen CL, Meng E, Wu ST, Lai HF, Lu YS, Yang MH, Tsao CW, Kao CC, Chiu YL. Targeting May Result in Enhanced Migration of Cancer Cells in Bladder Carcinoma. Cancers. 13. PMID 34503284 DOI: 10.3390/cancers13174474   
2021 Zhang Y, Jia H, Liu Z, Guo J, Li Y, Li R, Zhu G, Li J, Li M, Li X, Wang S, Dang C, Zhao T. D-MT prompts the anti-tumor effect of oxaliplatin by inhibiting IDO expression in a mouse model of colon cancer. International Immunopharmacology. 101: 108203. PMID 34649091 DOI: 10.1016/j.intimp.2021.108203   
2021 Brun S, Pascussi JM, Gifu EP, Bestion E, Macek-Jilkova Z, Wang G, Bassissi F, Mezouar S, Courcambeck J, Merle P, Decaens T, Pannequin J, Halfon P, Caron de Fromentel C. GNS561, a New Autophagy Inhibitor Active against Cancer Stem Cells in Hepatocellular Carcinoma and Hepatic Metastasis from Colorectal Cancer. Journal of Cancer. 12: 5432-5438. PMID 34405006 DOI: 10.7150/jca.58533   
2021 Gu W, Yang J, Wang Y, Xu J, Wang X, Du F, Hu X, Guo H, Song C, Tao R, Zhang X. Comprehensive identification of alterations in 5 557 Chinese patients with solid tumors by next-generation sequencing. American Journal of Cancer Research. 11: 3893-3906. PMID 34522456   
2021 Mimura K, Kikuchi T, Kono K. [The Association between Intestinal Bacteria and Tumor Infiltrating Immune Cells in the Tumor Microenvironment of Colorectal Cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 48: 1093-1095. PMID 34521782   
2021 Qiu H, Shao Z, Wen X, Jiang J, Ma Q, Wang Y, Huang L, Ding X, Zhang L. TREM2: Keeping Pace With Immune Checkpoint Inhibitors in Cancer Immunotherapy. Frontiers in Immunology. 12: 716710. PMID 34539652 DOI: 10.3389/fimmu.2021.716710   
2021 Liu PF, Shu CW, Lee CH, Sie HC, Liou HH, Cheng JT, Ger LP, Chen CL, Chen CC, Chen CF. Clinical Significance and the Role of Guanylate-Binding Protein 5 in Oral Squamous Cell Carcinoma. Cancers. 13. PMID 34439200 DOI: 10.3390/cancers13164043   
2021 Di Capua D, Bracken-Clarke D, Ronan K, Baird AM, Finn S. The Liquid Biopsy for Lung Cancer: State of the Art, Limitations and Future Developments. Cancers. 13. PMID 34439082 DOI: 10.3390/cancers13163923   
2021 Gao Y, Wang J, Han H, Xiao H, Jin WK, Wang S, Shao S, Wang Z, Yang W, Wang L, Weng L. A nanoparticle-containing polycaprolactone implant for combating post-resection breast cancer recurrence. Nanoscale. 13: 14417-14425. PMID 34473184 DOI: 10.1039/d1nr04125h   
2021 Haque MR, Rempert TH, Al-Hilal TA, Wang C, Bhushan A, Bishehsari F. Organ-Chip Models: Opportunities for Precision Medicine in Pancreatic Cancer. Cancers. 13. PMID 34503294 DOI: 10.3390/cancers13174487   
2021 Kobayashi H, Gieniec KA, Ng JQ, Goyne J, Lannagan TRM, Thomas EM, Radford G, Wang T, Suzuki N, Ichinose M, Wright JA, Vrbanac L, Burt AD, Takahashi M, Enomoto A, et al. Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma. Journal of Visualized Experiments : Jove. PMID 34542536 DOI: 10.3791/62630   
2021 Qiao Q, Bai R, Song W, Gao H, Zhang M, Lu J, Hong M, Zhang X, Sun P, Zhang Q, Zhao P. Human α-Defensin 5 suppressed Colon Cancer Growth by Targeting PI3K pathway. Experimental Cell Research. 112809. PMID 34487729 DOI: 10.1016/j.yexcr.2021.112809   
2021 Yesilkanal AE, Johnson GL, Ramos AF, Rosner MR. New strategies for targeting kinase networks in cancer. The Journal of Biological Chemistry. 101128. PMID 34461089 DOI: 10.1016/j.jbc.2021.101128   
2021 Zboril E, Yoo H, Chen L, Liu Z. Dynamic Interactions of Transcription Factors and Enhancer Reprogramming in Cancer Progression. Frontiers in Oncology. 11: 753051. PMID 34616687 DOI: 10.3389/fonc.2021.753051   
2021 Yan Y, Liang Q, Xu Z, Yi Q. Integrative bioinformatics and experimental analysis revealed down-regulated CDC42EP3 as a novel prognostic target for ovarian cancer and its roles in immune infiltration. Peerj. 9: e12171. PMID 34616622 DOI: 10.7717/peerj.12171   
2021 Farshadi EA, Chang J, Sampadi B, Doukas M, Van 't Land F, van der Sijde F, Vietsch EE, Pothof J, Groot Koerkamp B, van Eijck CHJ. Organoids derived from neoadjuvant FOLFIRINOX patients recapitulate therapy resistance in pancreatic ductal adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34580113 DOI: 10.1158/1078-0432.CCR-21-1681   
2021 Guo R, Zhang D, Zhang C, Yang Y, Liu H, Yang Y, Lin J. Immunotoxin IHP25-BT with low immunogenicity and off-target toxicity inhibits the growth and metastasis of trastuzumab-resistant tumor cells. International Journal of Pharmaceutics. 121081. PMID 34506924 DOI: 10.1016/j.ijpharm.2021.121081   
2021 Saif MW, Rajagopal S, Caplain J, Goodman MD, Popowich D, Orkin BA, Tsichlis PN, Martell R. The First Study Evaluating the Safety of Pre-Surgery Administration of Metformin in Patients with Colorectal and other Gastrointestinal Cancers and Effect on Cancer Stem Cells. Cancer Medicine Journal. 4: 1-10. PMID 34368808   
2021 Nachtigal MW, Musaphir P, Dhiman S, Altman AD, Schweizer F, Arthur G. Cytotoxic capacity of a novel glycosylated antitumor ether lipid in chemotherapy-resistant high grade serous ovarian cancer in vitro and in vivo. Translational Oncology. 14: 101203. PMID 34416424 DOI: 10.1016/j.tranon.2021.101203   
2021 Zhou J, Jiang X, Amy Xia H, Wei P, Hobbs BP. A survival mediation model with Bayesian model averaging. Statistical Methods in Medical Research. 9622802211037069. PMID 34448657 DOI: 10.1177/09622802211037069   
2021 DeNardo DG, Galkin A, Dupont J, Zhou L, Bendell J. GB1275, a first-in-class CD11b modulator: rationale for immunotherapeutic combinations in solid tumors. Journal For Immunotherapy of Cancer. 9. PMID 34452928 DOI: 10.1136/jitc-2021-003005   
2021 Boldrini L, Faviana P, Galli L, Paolieri F, Erba PA, Bardi M. Multi-Dimensional Scaling Analysis of Key Regulatory Genes in Prostate Cancer Using the TCGA Database. Genes. 12. PMID 34573332 DOI: 10.3390/genes12091350