Lucas Bleicher - Publications

Affiliations: 
Universidade Federal de Minas Gerais (UFMG) 
Area:
Crystallography,Biochemistry,Computational Biology

22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Fonseca NJ, Afonso MQL, Carrijo L, Bleicher L. CONAN: A web application to detect specificity determinants and functional sites by amino acids co-variation network analysis. Bioinformatics (Oxford, England). PMID 32780795 DOI: 10.1093/Bioinformatics/Btaa713  0.328
2020 Querino Lima Afonso M, Fonseca NJ, de Oliveira LC, Lobo FP, Bleicher L. Coevolved Positions represent key functional properties in the Trypsin-like Serine Proteases Protein Family. Journal of Chemical Information and Modeling. PMID 31895561 DOI: 10.1021/Acs.Jcim.9B00903  0.39
2019 Coitinho JB, Costa MAF, Melo EM, Morais EA, de Andrade LGA, da Rocha AM, de Magalhães MTQ, Favaro DC, Bleicher L, Pedroso ERP, Goes AM, Nagem RAP. Structural and immunological characterization of a new nucleotidyltransferase-like antigen from Paracoccidioides brasiliensis. Molecular Immunology. 112: 151-162. PMID 31108423 DOI: 10.1016/J.Molimm.2019.04.028  0.418
2018 José da Fonseca N, Querino Lima Afonso M, Carrijo de Oliveira L, Bleicher L. A new method bridging graph theory and residue co-evolutionary networks for specificity determinant positions detection. Bioinformatics (Oxford, England). PMID 30295749 DOI: 10.1093/Bioinformatics/Bty846  0.316
2018 Gomes-Lima CJ, Maciel AAFL, Andrade MO, Cunha VSD, Mazzeu JF, Bleicher L, Neves FAR, Lofrano-Porto A. Thyroxine-binding globulin deficiency due to a novel SERPINA7 mutation: Clinical characterization, analysis of X-chromosome inactivation pattern and protein structural modeling. Gene. 666: 58-63. PMID 29733970 DOI: 10.1016/J.Gene.2018.05.018  0.326
2018 Oliveira A, Bleicher L, Schrago CG, Silva Junior FP. Conservation analysis and decomposition of residue correlation networks in the phospholipase A2 superfamily (PLA2s): Insights into the structure-function relationships of snake venom toxins. Toxicon : Official Journal of the International Society On Toxinology. 146: 50-60. PMID 29608922 DOI: 10.1016/J.Toxicon.2018.03.013  0.428
2018 Fonseca-Júnior NJ, Afonso MQL, Oliveira LC, Bleicher L. PFstats: A Network-Based Open Tool for Protein Family Analysis. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 25: 480-486. PMID 29481292 DOI: 10.1089/Cmb.2017.0181  0.364
2017 Rios-Anjos RM, Camandona VL, Bleicher L, Ferreira-Junior JR. Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae. Plos One. 12: e0177090. PMID 28472157 DOI: 10.1371/Journal.Pone.0177090  0.347
2017 da Fonseca NJ, Lima Afonso MQ, Pedersolli NG, de Oliveira LC, Andrade DS, Bleicher L. Sequence, structure and function relationships in flaviviruses as assessed by evolutive aspects of its conserved non-structural protein domains. Biochemical and Biophysical Research Communications. 492: 565-571. PMID 28087275 DOI: 10.1016/J.Bbrc.2017.01.041  0.4
2015 Busso C, Ferreira-Júnior JR, Paulela JA, Bleicher L, Demasi M, Barros MH. Coq7p relevant residues for protein activity and stability. Biochimie. 119: 92-102. PMID 26497406 DOI: 10.1016/J.Biochi.2015.10.016  0.32
2011 Bleicher L, Lemke N, Garratt RC. Using amino acid correlation and community detection algorithms to identify functional determinants in protein families. Plos One. 6: e27786. PMID 22205928 DOI: 10.1371/Journal.Pone.0027786  0.533
2011 Bleicher L, Prates ET, Gomes TC, Silveira RL, Nascimento AS, Rojas AL, Golubev A, Martínez L, Skaf MS, Polikarpov I. Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from Rhodothermus marinus and molecular dynamics simulations. The Journal of Physical Chemistry. B. 115: 7940-9. PMID 21619042 DOI: 10.1021/Jp200330Z  0.365
2011 Bachega JF, Bleicher L, Horjales ER, Santiago PS, Garratt RC, Tabak M. Crystallization and preliminary structural analysis of the giant haemoglobin from Glossoscolex paulistus at 3.2 Ã…. Journal of Synchrotron Radiation. 18: 24-8. PMID 21169685 DOI: 10.1107/S090904951002772X  0.529
2010 Palmieri Lde C, Lima LM, Freire JB, Bleicher L, Polikarpov I, Almeida FC, Foguel D. Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition. The Journal of Biological Chemistry. 285: 31731-41. PMID 20659897 DOI: 10.1074/Jbc.M110.157206  0.37
2010 Busso C, Bleicher L, Ferreira-Júnior JR, Barros MH. Site-directed mutagenesis and structural modeling of Coq10p indicate the presence of a tunnel for coenzyme Q6 binding. Febs Letters. 584: 1609-14. PMID 20303962 DOI: 10.1016/J.Febslet.2010.03.024  0.38
2010 Trivella DB, Bleicher L, Palmieri Lde C, Wiggers HJ, Montanari CA, Kelly JW, Lima LM, Foguel D, Polikarpov I. Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding. Journal of Structural Biology. 170: 522-31. PMID 20211733 DOI: 10.1016/J.Jsb.2010.03.002  0.33
2010 Watanabe L, de Moura PR, Bleicher L, Nascimento AS, Zamorano LS, Calvete JJ, Sanz L, Pérez A, Bursakov S, Roig MG, Shnyrov VL, Polikarpov I. Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia). Journal of Structural Biology. 169: 226-42. PMID 19854274 DOI: 10.1016/J.Jsb.2009.10.009  0.403
2009 Bachega JFR, Navarro MVAS, Bleicher L, Bortoleto-Bugs RK, Dive D, Hoffmann P, Viscogliosi E, Garratt RC. Systematic structural studies of iron superoxide dismutases from human parasites and a statistical coupling analysis of metal binding specificity Proteins: Structure, Function and Bioinformatics. 77: 26-37. PMID 19384994 DOI: 10.1002/Prot.22412  0.536
2008 Golubev AM, Rojas AL, Nascimento AS, Bleicher L, Kulminskaya AA, Eneyskaya EV, Polikarpov I. Crystallization and preliminary crystallographic analysis of laminarinase from Rhodothermus marinus: a case of pseudomerohedral twinning. Protein and Peptide Letters. 15: 1142-4. PMID 19075828 DOI: 10.2174/092986608786071139  0.303
2008 Kuser P, Cupri F, Bleicher L, Polikarpov I. Crystal structure of yeast hexokinase PI in complex with glucose: A classical "induced fit" example revised. Proteins. 72: 731-40. PMID 18260108 DOI: 10.1002/Prot.21956  0.364
2007 Matozo HC, Santos MA, de Oliveira Neto M, Bleicher L, Lima LM, Iuliano R, Fusco A, Polikarpov I. Low-resolution structure and fluorescence anisotropy analysis of protein tyrosine phosphatase eta catalytic domain. Biophysical Journal. 92: 4424-32. PMID 17400699 DOI: 10.1529/Biophysj.106.094961  0.392
2006 Nascimento AS, Dias SMG, Nunes FM, Aparício R, Ambrosio ALB, Bleicher L, Figueira ACM, Santos MAM, Neto MdO, Fischer H, Togashi M, Craievich AF, Garratt RC, Baxter JD, Webb P, et al. Structural Rearrangements in the Thyroid Hormone Receptor Hinge Domain and Their Putative Role in the Receptor Function Journal of Molecular Biology. 360: 586-598. PMID 16781732 DOI: 10.1016/J.Jmb.2006.05.008  0.539
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