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195/500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Chan M, Ahmadi A, Yao S, Sato-Kaneko F, Messer K, Pu M, Nguyen B, Hayashi T, Corr M, Carson D, Cottam HB, Shukla N. Identification of Biologically Active Pyrimido[5,4-b] indoles that Prolong NF-κB Activation Without Intrinsic Activity. Acs Combinatorial Science. PMID 28657707 DOI: 10.1021/Acscombsci.7B00080  0.302
2017 Wu C, Vinogradova E, Lao F, Nan E, Ta K, Messer K, Choi M, Cravatt BF, Carson DA. Proteomic Analysis Reveals IRAK4 As a Therapeutic Target in Chronic Lymphocytic Leukemia Blood. 130: 3838-3838. DOI: 10.1182/Blood.V130.Suppl_1.3838.3838  0.354
2016 Wu C, Lao FS, Nan E, Li H, Choi MY, Messer K, Carson DA. Inhibition of Casein Kinase 2 Impairs Wnt Signaling and Cell Survival in Chronic Lymphocytic Leukemia Blood. 128: 2050-2050. DOI: 10.1182/Blood.V128.22.2050.2050  0.359
2015 Wu C, Lao FS, Choi MY, Carson DA. Pharmacologic Modulation of STAT1 and Wnt Signaling in Chronic Lymphocytic Leukemia Blood. 126: 4150-4150. DOI: 10.1182/Blood.V126.23.4150.4150  0.353
2014 Tsoukas CD, Valentine M, Lotz M, Vaughan JH, Carson DA. The role of the T3 molecular complex in antigen recognition and subsequent activation events. Immunology Today. 5: 311-3. PMID 25290752 DOI: 10.1016/0167-5699(84)90121-X  0.32
2014 Wu CC, Lao F, Li H, Rassenti L, Kipps TJ, Messer K, Carson DA, Choi MY. Inhibition of Wnt Signaling By Dimethyl Fumarate Results in in Vitro and in Vivo Clearance of Chronic Lymphocytic Leukemia Cells and Has Additive Activity with Ibrutinib Blood. 124: 4683-4683. DOI: 10.1182/Blood.V124.21.4683.4683  0.386
2014 Zhang S, Cui B, Lai H, Liu G, Wu C, Widhopf G, Wu R, Lao F, Schwab R, Carson D, Kipps TJ. Abstract 206: Depletion of ovarian cancer initiating cells by a monoclonal antibody against ROR1 Cancer Research. 74: 206-206. DOI: 10.1158/1538-7445.Am2014-206  0.34
2013 Wu CC, Choi MY, Lao F, Kipps TJ, Carson DA. Inhibition Of Wnt Signaling In Chronic Lymphocytic Leukemia Has Synergistic Cytotoxicity With Ibrutinib Blood. 122: 5306-5306. DOI: 10.1182/Blood.V122.21.5306.5306  0.356
2013 Yu J, Cui B, Widhopf GF, Chen L, Rassenti L, Wang Z, Ma S, Hayashi T, Carson DA, Kipps TJ. Preclinical Development Of ROR1 Peptide Based Vaccine With Activity Against Chronic Lymphocytic Leukemia In ROR1 Transgenic Mice Blood. 122: 4174-4174. DOI: 10.1182/Blood.V122.21.4174.4174  0.321
2013 Widhopf GF, Cui B, Wu CC, Yu J, Lao F, Tawatao R, Wu R, Avery E, Sadarangani A, Prussak C, Jamieson CH, Carson DA, Kipps TJ. Targeting Of Chronic Lymphocytic Leukemia B Cells With a Humanized Monoclonal Antibody Specific For ROR1 Blood. 122: 2873-2873. DOI: 10.1182/Blood.V122.21.2873.2873  0.389
2013 Cui B, Widhopf GF, Prussak CE, Wu CCN, Sadarangani A, Zhang S, Lao F, Jamieson CH, Carson DA, Kipps TJ. Cirmtuzumab Vedotin (UC-961ADC3), An Anti-ROR1-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment For ROR1-Positive Leukemia and Solid Tumors Blood. 122: 1637-1637. DOI: 10.1182/Blood.V122.21.1637.1637  0.395
2012 Hellqvist E, Wu CC, Widhopf GF, Shih A, Tawatao R, Lao F, Cui B, Prussak C, Sadarangani A, Carson DA, Jamieson C, Kipps TJ. Selective Clearance of Chronic Lymphocytic Leukemia Cells in Vivo Following Treatment with UC99961, an Anti-ROR1 Monoclonal Antibody Blood. 120: 3886-3886. DOI: 10.1182/Blood.V120.21.3886.3886  0.38
2012 Balaian L, Sadarangani A, Widhopf GF, Zhong R, Prussak C, Marra MA, Dick JE, Minden MD, Ball ED, Carson DA, Jamieson C, Kipps TJ. A Highly Selective Anti-ROR1 Monoclonal Antibody Inhibits Human Acute Myeloid Leukemia CD34+ Cell Survival and Self-Renewal. Blood. 120: 2560-2560. DOI: 10.1182/Blood.V120.21.2560.2560  0.346
2011 Zhang S, Wu CC, Fecteau J, Cui B, Wu R, Rassenti LZ, Lao FS, Tawatao R, Weigland S, Prussak C, Carson DA, Kipps TJ. A Monoclonal Antibody Specifically Targeting CD44 Inhibits B-Cell Chronic Lymphocytic Leukemia Cell Survival In Vitro and In Vivo Blood. 118: 927-927. DOI: 10.1182/Blood.V118.21.927.927  0.334
2011 Chen L, Chen G, Fecteau J, Coffey G, Prussak C, Carson DA, Kipps T. Highly Specific Inhibitor for Syk Induces Chronic Lymphocytic Leukemia Cell Apoptosis, Blood. 118: 3875-3875. DOI: 10.1182/Blood.V118.21.3875.3875  0.374
2011 Wu RP, Wu CC, Hayashi T, Rassenti LZ, Kipps TJ, Carson DA. Increased Activity of Aldehyde Dehydrogenase, a Stem/Progenitor Cell Marker, in Chronic Lymphocytic Leukemia, Blood. 118: 3867-3867. DOI: 10.1182/Blood.V118.21.3867.3867  0.335
2011 T J, Hayashi T, Wu RP, Cottam H, Carson DA. Selective Inhibition of Activated B-Cell Lymphoma Cells by a Novel Small Molecule Inhibitor of NF-κB Blood. 118: 2498-2498. DOI: 10.1182/Blood.V118.21.2498.2498  0.343
2011 Choi MY, Cardenas JM, Lu D, Yu J, Stout EP, Wu RP, Horton JM, Gomez A, Diaz-Perez JA, Carson DA, Molinski TF, Kipps TJ, Castro JE. Agelastatin A (AgA), a Marine Sponge Derived Alkaloid, Inhibits Wnt/Beta-Catenin Signaling and Selectively Induces Apoptosis in Chronic Lymphocytic Leukemia Independently of p53 Blood. 118: 1786-1786. DOI: 10.1182/Blood.V118.21.1786.1786  0.354
2011 Ma W, Gutierrez A, Goff D, Geron I, Sadarangani A, Shih A, Recart AC, Jiang Q, Wu JC, Wu CC, Leu H, Wall R, Geyrozaga R, Diccianni M, Li K, ... ... Carson D, et al. Abstract 974: A selective Notch1 mAb targets leukemia progenitor cells in T-ALL Cancer Research. 71: 974-974. DOI: 10.1158/1538-7445.Am2011-974  0.322
2009 Wu RP, Hayashi T, Yao S, Wu CC, Cottam HB, Rosenbach M, Schwab RB, Carson DA. Oxidative Stress Response and Cytotoxicity of Electrophilic Compounds in Primary Human Chronic Lymphocytic Leukemia. Blood. 114: 3444-3444. DOI: 10.1182/Blood.V114.22.3444.3444  0.37
2007 Daniels GA, Chan M, Wu CC, Tawatao R, Messmer D, Eftimie B, Cottam H, Carson D. Covalent coupling of a novel TLR7 agonist to antigen elicits an effective immune response in a murine melanoma tumor model Journal of Clinical Oncology. 25: 3019-3019. DOI: 10.1200/Jco.2007.25.18_Suppl.3019  0.32
2006 Castro JE, Prada CE, Aguillon RA, Kitada S, Fukuda T, Motta M, Wu C, Dicker F, Sun G, Wang JY, Carson DA, Reed JC, Kipps TJ. Thymidine-phosphorothioate oligonucleotides induce activation and apoptosis of CLL cells independently of CpG motifs or BCL-2 gene interference. Leukemia. 20: 680-8. PMID 16498393 DOI: 10.1038/Sj.Leu.2404144  0.348
2006 Kavalerchik E, Gotlib J, Geron I, Abrahamsson A, Wrasidlo W, Goff D, Lu D, Molinski T, Giles F, Weissman I, Carson D, Jamieson C. Inhibition of Chronic Myelogenous Leukemia Stem Cells with Novel Wnt Antagonists. Blood. 108: 238-238. DOI: 10.1182/Blood.V108.11.238.238  0.32
2005 Barchéchath SD, Tawatao RI, Corr M, Carson DA, Cottam HB. Inhibitors of apoptosis in lymphocytes: synthesis and biological evaluation of compounds related to pifithrin-alpha. Journal of Medicinal Chemistry. 48: 6409-22. PMID 16190767 DOI: 10.1021/Jm0502034  0.745
2005 Barchéchath SD, Tawatao RI, Corr M, Carson DA, Cottam HB. Quinolinium salt as a potent inhibitor of lymphocyte apoptosis. Bioorganic & Medicinal Chemistry Letters. 15: 1785-8. PMID 15780606 DOI: 10.1016/J.Bmcl.2005.02.047  0.746
2005 Chuang H, Liu Y, Rassenti LZ, Huynh L, Carson D, Kipps TJ. Expression of Lymphocyte Activation Gene 3 (LAG-3/CD223) by Chronic Lymphocytic Leukemia B Cells. Blood. 106: 2952-2952. DOI: 10.1182/Blood.V106.11.2952.2952  0.353
2004 Pedersen IM, Luciano F, Zhang X, Croce CM, Kipps TJ, Carson DA, Reed JC. Tcl-1 Inhibits Nuclear Export of TR3 and Is Highly Expressed in ZAP70-Positive CLL B-Cells. Blood. 104: 967-967. DOI: 10.1182/Blood.V104.11.967.967  0.349
2004 Fukuda T, Lu D, Carson DA, Kipps TJ. Restricted Expression of the Orphan Tyrosine Kinase Receptor ROR1 in Chronic Lymphocytic Leukemia. Blood. 104: 772-772. DOI: 10.1182/Blood.V104.11.772.772  0.356
2001 Van Uden JH, Tran CH, Carson DA, Raz E. Type I interferon is required to mount an adaptive response to immunostimulatory DNA. European Journal of Immunology. 31: 3281-90. PMID 11745345 DOI: 10.1002/1521-4141(200111)31:11<3281::Aid-Immu3281>3.0.Co;2-0  0.761
2001 Hayashi T, Rao SP, Takabayashi K, Van Uden JH, Kornbluth RS, Baird SM, Taylor MW, Carson DA, Catanzaro A, Raz E. Enhancement of innate immunity against Mycobacterium avium infection by immunostimulatory DNA is mediated by indoleamine 2,3-dioxygenase. Infection and Immunity. 69: 6156-64. PMID 11553555 DOI: 10.1128/Iai.69.10.6156-6164.2001  0.774
2001 Uchijima M, Raz E, Carson DA, Nagata T, Koide Y. Identification of immunostimulatory DNA-induced genes by suppression subtractive hybridization. Biochemical and Biophysical Research Communications. 286: 688-91. PMID 11520051 DOI: 10.1006/Bbrc.2001.5453  0.333
2000 Kyburz D, Carson DA, Corr M. The role of CD40 ligand and tumor necrosis factor alpha signaling in the transgenic K/BxN mouse model of rheumatoid arthritis. Arthritis and Rheumatism. 43: 2571-7. PMID 11083282 DOI: 10.1002/1529-0131(200011)43:11<2571::Aid-Anr26>3.0.Co;2-4  0.322
2000 Genini D, Adachi S, Chao Q, Rose DW, Carrera CJ, Cottam HB, Carson DA, Leoni LM. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria. Blood. 96: 3537-43. PMID 11071652 DOI: 10.1182/Blood.V96.10.3537.H8003537_3537_3543  0.333
2000 Leoni LM, Hamel E, Genini D, Shih H, Carrera CJ, Cottam HB, Carson DA. Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells. Journal of the National Cancer Institute. 92: 217-24. PMID 10655438 DOI: 10.1093/Jnci/92.3.217  0.308
2000 Genini D, Budihardjo I, Plunkett W, Wang X, Carrera CJ, Cottam HB, Carson DA, Leoni LM. Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway. The Journal of Biological Chemistry. 275: 29-34. PMID 10617581 DOI: 10.1074/Jbc.275.1.29  0.339
1999 Bonnin D, Prakken B, Samodal R, La Cava A, Carson DA, Albani S. Ontogeny of synonymous T cell populations with specificity for a self MHC epitope mimicked by a bacterial homologoue: an antigen-specific T cell analysis in a non-transgenic system. European Journal of Immunology. 29: 3826-36. PMID 10601990 DOI: 10.1002/(Sici)1521-4141(199912)29:12<3826::Aid-Immu3826>3.0.Co;2-S  0.323
1999 Chao Q, Deng L, Shih H, Leoni LM, Genini D, Carson DA, Cottam HB. Substituted isoquinolines and quinazolines as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha. Journal of Medicinal Chemistry. 42: 3860-73. PMID 10508435 DOI: 10.1021/Jm9805900  0.339
1999 Warnatz K, Kyburz D, Brinson DC, Lee DJ, Von Damm A, Engelhart M, Corr M, Carson DA, Tighe H. Rheumatoid factor B cell tolerance via autonomous Fas/FasL-independent apoptosis. Cellular Immunology. 191: 69-73. PMID 9918688 DOI: 10.1006/Cimm.1998.1415  0.387
1998 Leoni LM, Chao Q, Cottam HB, Genini D, Rosenbach M, Carrera CJ, Budihardjo I, Wang X, Carson DA. Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c. Proceedings of the National Academy of Sciences of the United States of America. 95: 9567-71. PMID 9689121 DOI: 10.1073/Pnas.95.16.9567  0.354
1998 Leoni LM, Shih HC, Deng L, Tuey C, Walter G, Carson DA, Cottam HB. Modulation of ceramide-activated protein phosphatase 2A activity by low molecular weight aromatic compounds. Biochemical Pharmacology. 55: 1105-11. PMID 9605434 DOI: 10.1016/S0006-2952(97)00685-0  0.312
1998 Lee DJ, Abeyratne A, Carson DA, Corr M. Induction of an antigen-specific, CD1-restricted cytotoxic T lymphocyte response In vivo. The Journal of Experimental Medicine. 187: 433-8. PMID 9449723 DOI: 10.1084/Jem.187.3.433  0.345
1998 Mizushima N, Kohsaka H, Nanki T, Ollier WE, Carson DA, Miyasaka N. HLA-dependent peripheral T cell receptor (TCR) repertoire formation and its modification by rheumatoid arthritis (RA) Clinical and Experimental Immunology. 110: 428-33. PMID 9409647 DOI: 10.1046/J.1365-2249.1997.4331451.X  0.311
1997 Lee KS, Cottam HB, Houglum K, Wasson DB, Carson D, Chojkier M. Pentoxifylline blocks hepatic stellate cell activation independently of phosphodiesterase inhibitory activity. American Journal of Physiology. Gastrointestinal and Liver Physiology. 273: G1094-G1100. PMID 29585426 DOI: 10.1152/Ajpgi.1997.273.5.G1094  0.339
1997 Roman M, Martin-Orozco E, Goodman JS, Nguyen MD, Sato Y, Ronaghy A, Kornbluth RS, Richman DD, Carson DA, Raz E. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants Nature Medicine. 3: 849-854. PMID 9256274 DOI: 10.1038/Nm0897-849  0.318
1997 La Cava A, Nelson JL, Ollier WER, MacGregor A, Keystone EC, Thorne JC, Scavulli JF, Berry CC, Carson DA, Albani S. Genetic bias in immune responses to a cassette shared by different microorganisms in patients with rheumatoid arthritis Journal of Clinical Investigation. 100: 658-663. PMID 9239413 DOI: 10.1172/Jci119577  0.313
1997 Lee DJ, Tighe H, Corr M, Roman M, Carson DA, Spiegelberg HL, Raz E. Inhibition of IgE antibody formation by plasmid DNA immunization is mediated by both CD4+ and CD8+ T cells International Archives of Allergy and Immunology. 113: 227-230. PMID 9130530 DOI: 10.1159/000237554  0.31
1997 Carson DA. Unconventional T-cell activation by IL-15 in rheumatoid arthritis Nature Medicine. 3: 148-149. PMID 9018227 DOI: 10.1038/Nm0297-148  0.304
1997 Tighe H, Warnatz K, Brinson D, Corr M, Weigle WO, Baird SM, Carson DA. Peripheral deletion of rheumatoid factor B cells after abortive activation by IgG Proceedings of the National Academy of Sciences of the United States of America. 94: 646-651. PMID 9012838 DOI: 10.1073/Pnas.94.2.646  0.405
1996 Corr M, Lee DJ, Carson DA, Tighe H. Gene vaccination with naked plasmid DNA: Mechanism of CTL priming Journal of Experimental Medicine. 184: 1555-1560. PMID 8879229 DOI: 10.1084/Jem.184.4.1555  0.308
1996 Nanki T, Kohsaka H, Mizushima N, Ollier WER, Carson DA, Miyasaka N. Genetic control of T cell receptor BJ gene expression in peripheral lymphocytes of normal and rheumatoid arthritis monozygotic twins Journal of Clinical Investigation. 98: 1594-1601. PMID 8833908 DOI: 10.1172/Jci118953  0.334
1996 England NL, Cuthbert AP, Trott DA, Jezzard S, Nobori T, Carson DA, Newbold RF. Identification of human tumour suppressor genes by monochromosome transfer: Rapid growth-arrest response mapped to 9p21. Is mediated solely by the cyclin-D-dependent kinase inhibitor gene, CDKN2A (p16(INK4A)) Carcinogenesis. 17: 1567-1575. PMID 8761411 DOI: 10.1093/Carcin/17.8.1567  0.34
1996 Sato Y, Roman M, Tighe H, Lee D, Corr M, Nguyen MD, Silverman GJ, Lotz M, Carson DA, Raz E. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization Science. 273: 352-354. PMID 8662521 DOI: 10.1126/Science.273.5273.352  0.324
1996 Nobori T, Takabayashi K, Tran P, Orvis L, Batova A, Yu AL, Carson DA. Genomic cloning of methylthioadenosine phosphorylase: A purine metabolic enzyme deficient in multiple different cancers Proceedings of the National Academy of Sciences of the United States of America. 93: 6203-6208. PMID 8650244 DOI: 10.1073/Pnas.93.12.6203  0.302
1996 Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, Swain SL, Spiegelberg HL, Carson DA. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization Proceedings of the National Academy of Sciences of the United States of America. 93: 5141-5145. PMID 8643542 DOI: 10.1073/Pnas.93.10.5141  0.348
1995 Raz E, Dudler J, Lotz M, Baird SM, Berry CC, Eisenberg RA, Carson DA. Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene delivery Lupus. 4: 286-292. PMID 8528225 DOI: 10.1177/096120339500400409  0.312
1995 Tighe H, Heaphy P, Baird S, Weigle WO, Carson DA. Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice Journal of Experimental Medicine. 181: 599-606. PMID 7836915 DOI: 10.1084/Jem.181.2.599  0.398
1995 Albani S, Keystone EC, Nelson JL, Ollier WER, La Cava A, Montemayor AC, Weber DA, Montecucco C, Martini A, Carson DA. Positive selection in autoimmunity: Abnormal immune responses to a bacterial dnaJ antigenic determinant in patients with early rheumatoid arthritis Nature Medicine. 1: 448-452. PMID 7585093 DOI: 10.1038/Nm0595-448  0.35
1994 Albani S, Ravelli A, Massa M, Benedetti Fd, Andree G, Roudier J, Martini A, Carson DA. Immune responses to the Escherichia coli dnaJ heat shock protein in juvenile rheumatoid arthritis and their correlation with disease activity The Journal of Pediatrics. 124: 561-565. PMID 8151470 DOI: 10.1016/S0022-3476(05)83134-8  0.301
1994 Raz E, Carson DA, Parker SE, Parr TB, Abai AM, Aichinger G, Gromkowski SH, Singh M, Lew D, Yankauckas MA. Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proceedings of the National Academy of Sciences of the United States of America. 91: 9519-23. PMID 7937799 DOI: 10.1073/Pnas.91.20.9519  0.346
1993 Kohsaka H, Chen PP, Taniguchi A, Ollier WER, Carson DA. Divergent T cell receptor γ repertoires in rheumatoid arthritis monozygotic twins Arthritis and Rheumatism. 36: 213-221. PMID 8431211 DOI: 10.1002/Art.1780360212  0.306
1993 Tighe H, Chen PP, Tucker R, Kipps TJ, Roudier J, Jirik FR, Carson DA. Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice Journal of Experimental Medicine. 177: 109-118. PMID 8418195 DOI: 10.1084/Jem.177.1.109  0.385
1993 Machold KP, Carson DA, Lotz M. Transforming growth factor-β (TGFβ) inhibition of epstein-barr virus (EBV)- and interleukin-4 (IL-4)-induced immunoglobulin production in human B lymphocytes Journal of Clinical Immunology. 13: 219-227. PMID 8391546 DOI: 10.1007/Bf00919975  0.316
1993 Kohsaka H, Taniguchi A, Chen PP, Ollier WER, Carson DA. The expressed T cell receptor V gene repertoire of rheumatoid arthritis monozygotic twins: Rapid analysis by anchored polymerase chain reaction and enzyme-linked immunosorbent assay European Journal of Immunology. 23: 1895-1901. PMID 8344352 DOI: 10.1002/Eji.1830230825  0.327
1993 Cottam HB, Bruce Wasson D, Shih HC, Raychaudhuri A, Di Pasquale G, Carson DA. New adenosine kinase inhibitors with oral antiinflammatory activity: Synthesis and biological evaluation Journal of Medicinal Chemistry®. 36: 3424-3430. PMID 8230132 DOI: 10.1021/Jm00074A024  0.321
1993 Kawasaki H, Carrera CJ, Piro LD, Saven A, Kipps TJ, Carson DA. Relationship of deoxycytidine kinase and cytoplasmic 5′-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine Blood. 81: 597-601. PMID 8094016 DOI: 10.1182/Blood.V81.3.597.Bloodjournal813597  0.303
1993 Kohsaka H, Chen PP, Taniguchi A, Ollier WER, Carson DA. Regulation of the mature human T cell receptor γ repertoire by biased V-J gene rearrangement Journal of Clinical Investigation. 91: 171-178. PMID 7678601 DOI: 10.1172/Jci116167  0.324
1992 Olee T, Lu EW, Huang DF, Soto-Gil RW, Deftos M, Kozin F, Carson DA, Chen PP. Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven response. The Journal of Experimental Medicine. 175: 831-42. PMID 1740665 DOI: 10.1084/Jem.175.3.831  0.329
1992 Martin T, Duffy SF, Carson DA, Kipps TJ. Evidence for somatic selection of natural autoantibodies. The Journal of Experimental Medicine. 175: 983-91. PMID 1552291 DOI: 10.1084/Jem.175.4.983  0.36
1992 Kawasaki H, Carrera CJ, Carson DA. Quantitative immunoassay of human deoxycytidine kinase in malignant cells Analytical Biochemistry. 207: 193-196. PMID 1489095 DOI: 10.1016/0003-2697(92)90522-9  0.316
1992 Kobayashi R, Picchio G, Kirven M, Meisenholder G, Baird S, Carson DA, Mosier DE, Kipps TJ. Transfer of human chronic lymphocytic leukemia to mice with severe combined immune deficiency. Leukemia Research. 16: 1013-23. PMID 1383641 DOI: 10.1016/0145-2126(92)90081-H  0.368
1992 Kipps TJ, Rassenti LZ, Duffy S, Johnson T, Kobayashi R, Carson DA. Immunoglobulin V gene expression in CD5 B-cell malignancies. Annals of the New York Academy of Sciences. 651: 373-83. PMID 1376056 DOI: 10.1111/J.1749-6632.1992.Tb24638.X  0.341
1992 Carson DA, Wasson DB, Esparza LM, Carrera CJ, Kipps TJ, Cottam HB. Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine. Proceedings of the National Academy of Sciences of the United States of America. 89: 2970-4. PMID 1348362 DOI: 10.1073/Pnas.89.7.2970  0.345
1992 Huang DF, Olee T, Masuho Y, Matsumoto YI, Carson DA, Chen PP. Sequence analyses of three immunoglobulin G anti-virus antibodies reveal their utilization of autoantibody-related immunoglobulin Vh genes, but not Vλ genes Journal of Clinical Investigation. 90: 2197-2208. PMID 1334971 DOI: 10.1172/Jci116105  0.306
1991 Kipps TJ, Rassenti LZ, Duffy S, Kobayashi R, Martin T, Chen PP, Carson DA. Immunoglobulin Gene Rearrangement and Expression in B-CLL. Leukemia & Lymphoma. 5: 39-45. PMID 27463478 DOI: 10.3109/10428199109103377  0.354
1991 Beutler E, Piro LD, Saven A, Kay AC, McMillan R, Longmire R, Carrera CJ, Morin P, Carson DA. 2-Chlorodeoxyadenosine (2-CdA): A Potent Chemotherapeutic and Immunosuppressive Nucleoside. Leukemia & Lymphoma. 5: 1-8. PMID 27463204 DOI: 10.3109/10428199109068099  0.353
1991 Chen PP, Olsen NJ, Yang PM, Soto-Gil RW, Olee T, Siminovitch KA, Carson DA. From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all. International Reviews of Immunology. 5: 239-51. PMID 2130120 DOI: 10.3109/08830189009056732  0.335
1991 Terai C, Kornbluth RS, Pauza CD, Richman DD, Carson DA. Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1 Journal of Clinical Investigation. 87: 1710-1715. PMID 2022741 DOI: 10.1172/Jci115188  0.31
1991 Carson DA, Carrera CJ, Bruce Wasson D, Iizasa T. Deoxyadenosine-resistant human T lymphoblasts with elevated 5′-nucleotidase activity Bba - Molecular Cell Research. 1091: 22-28. PMID 1995064 DOI: 10.1016/0167-4889(91)90216-K  0.33
1991 Carson DA, Chen PP, Kipps TJ. New roles for rheumatoid factor. The Journal of Clinical Investigation. 87: 379-83. PMID 1991824 DOI: 10.1172/Jci115007  0.34
1991 Terai C, Carson DA. Pyrimidine nucleotide and nucleic acid synthesis in human monocytes and macrophages. Experimental Cell Research. 193: 375-81. PMID 1706277 DOI: 10.1016/0014-4827(91)90110-G  0.333
1991 Yang PM, Crowley JJ, McDaniel DO, Koopman WJ, Kozin F, Carson DA, Chen PP. Genetic studies of four highly homologous rheumatoid factor-associated Vk genes in rheumatoid arthritis patients and normal individuals. Molecular Immunology. 28: 1073-83. PMID 1681428 DOI: 10.1016/0161-5890(91)90022-C  0.319
1991 Olee T, Yang PM, Siminovitch KA, Olsen NJ, Hillson J, Wu J, Kozin F, Carson DA, Chen PP. Molecular basis of an autoantibody-associated restriction fragment length polymorphism that confers susceptibility to autoimmune diseases. The Journal of Clinical Investigation. 88: 193-203. PMID 1676037 DOI: 10.1172/Jci115277  0.326
1991 Axelrod O, Silverman G, Dev V, Kyle R, Carson D, Kipps T. Idiotypic cross-reactivity of immunoglobulins expressed in Waldenstrom's macroglobulinemia, chronic lymphocytic leukemia, and mantle zone lymphocytes of secondary B-cell follicles Blood. 77: 1484-1490. DOI: 10.1182/Blood.V77.7.1484.1484  0.39
1990 Tighe H, Silverman GJ, Kozin F, Tucker R, Gulizia R, Peebles C, Lotz M, Rhodes G, Machold K, Mosier DE, Carson DA. Autoantibody production by severe combined immunodeficient mice reconstituted with synovial cells from rheumatoid arthritis patients. European Journal of Immunology. 20: 1843-1848. PMID 2209691 DOI: 10.1002/Eji.1830200832  0.359
1990 Yang PM, Olsen NJ, Siminovitch KA, Olee T, Kozin F, Carson DA, Chen PP. Possible deletion of a developmentally regulated heavy-chain variable region gene in autoimmune diseases. Proceedings of the National Academy of Sciences of the United States of America. 87: 7907-11. PMID 2122448 DOI: 10.1073/Pnas.87.20.7907  0.322
1990 Crowley JJ, Mageed RA, Silverman GJ, Chen PP, Kozin F, Erger RA, Jefferis R, Carson DA. The incidence of a new human cross-reactive idiotype linked to subgroup VHIII heavy chains. Molecular Immunology. 27: 87-94. PMID 2107394 DOI: 10.1016/0161-5890(90)90063-6  0.342
1990 Silverman GJ, Carson DA. Structural characterization of human monoclonal cold agglutinins: evidence for a distinct primary sequence-defined VH4 idiotype. European Journal of Immunology. 20: 351-6. PMID 2107084 DOI: 10.1002/Eji.1830200218  0.311
1990 Piro LD, Carrera CJ, Carson DA, Beutler E. Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine New England Journal of Medicine. 322: 1117-1121. PMID 1969613 DOI: 10.1056/Nejm199004193221605  0.304
1990 Carrera CJ, Terai C, Lotz M, Curd JG, Piro LD, Beutler E, Carson DA. Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy. The Journal of Clinical Investigation. 86: 1480-8. PMID 1700795 DOI: 10.1172/Jci114865  0.358
1990 Kekow J, Wachsman W, McCutchan JA, Cronin M, Carson DA, Lotz M. Transforming growth factor β and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection Proceedings of the National Academy of Sciences of the United States of America. 87: 8321-8325. PMID 1700428 DOI: 10.1073/Pnas.87.21.8321  0.319
1990 Kipps TJ, Robbins BA, Carson DA. Uniform high frequency expression of autoantibody-associated crossreactive idiotypes in the primary B cell follicles of human fetal spleen. The Journal of Experimental Medicine. 171: 189-96. PMID 1688607 DOI: 10.1084/Jem.171.1.189  0.369
1990 Silverman GJ, Chen PP, Carson DA. Cold agglutinins: specificity, idiotypy and structural analysis. Chemical Immunology. 48: 109-125. DOI: 10.1159/000318936  0.3
1989 Carson DA, Nobori T, Kajander EO, Carrera CJ, Kubota M, Yamanaka H. Methylthioadenosine (MeSAdo) phosphorylase deficiency in malignancy. Advances in Experimental Medicine and Biology. 250: 179-85. PMID 3151225 DOI: 10.1007/978-1-4684-5637-0_16  0.304
1989 PODOR TJ, JIRIK FR, LOSKUTOFF DJ, CARSON DA, LOTZ M. Human Endothelial Cells Produce IL‐6: Lack of Responses to Exogenous IL‐6 Annals of the New York Academy of Sciences. 557: 374-387. PMID 2660697 DOI: 10.1111/J.1749-6632.1989.Tb24030.X  0.302
1989 Carson DA, Piro LD, Wasson DB, Carrera CJ, Beutler E. Activity of 2-chloro-2'-deoxyadenosine in chronic lymphocytic leukemia, hairy cell leukemia, and autoimmune hemolytic anemia Advances in Experimental Medicine and Biology. 253: 427-431. PMID 2576181 DOI: 10.1007/978-1-4684-5673-8_70  0.323
1989 Mosier DE, Gulizia RJ, Baird SM, Spector S, Spector D, Kipps TJ, Fox RI, Carson DA, Cooper N, Richman DD. Studies of HIV infection and the development of Epstein-Barr virus-related B cell lymphomas following transfer of human lymphocytes to mice with severe combined immunodeficiency. Current Topics in Microbiology and Immunology. 152: 195-9. PMID 2553338 DOI: 10.1007/978-3-642-74974-2_23  0.357
1989 Kipps TJ, Tomhave E, Pratt LF, Duffy S, Chen PP, Carson DA. Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 86: 5913-7. PMID 2503826 DOI: 10.1073/Pnas.86.15.5913  0.38
1989 Chen PP, Liu MF, Glass CA, Sinha S, Kipps TJ, Carson DA. Characterization of two immunoglobulin VH genes that are homologous to human rheumatoid factors. Arthritis and Rheumatism. 32: 72-6. PMID 2492198 DOI: 10.1002/Anr.1780320112  0.31
1989 Roudier J, Petersen J, Rhodes GH, Luka J, Carson DA. Susceptibility to rheumatoid arthritis maps to a T-cell epitope shared by the HLA-Dw4 DR beta-1 chain and the Epstein-Barr virus glycoprotein gp110. Proceedings of the National Academy of Sciences of the United States of America. 86: 5104-8. PMID 2472638 DOI: 10.1073/Pnas.86.13.5104  0.343
1989 Mageed RA, Carson Da, Jefferis R. Analysis of rheumatoid factor autoantibodies in patients with essential mixed cryoglobulinaemia and rheumatoid arthritis. Scandinavian Journal of Rheumatology. Supplement. 75: 172-8. PMID 2467350 DOI: 10.3109/03009748809096759  0.314
1989 Yamanaka H, Willis EH, Carson DA. Human autoantibodies to poly(adenosine diphosphate-ribose) polymerase recognize cross-reactive epitopes associated with the catalytic site of the enzyme. The Journal of Clinical Investigation. 83: 180-6. PMID 2463266 DOI: 10.1172/Jci113856  0.317
1988 Chen PP, Liu MF, Sinha S, Carson DA. A 16/6 idiotype-positive anti-DNA antibody is encoded by a conserved VH gene with no somatic mutation. Arthritis and Rheumatism. 31: 1429-31. PMID 3263866 DOI: 10.1002/Art.1780311113  0.307
1988 Carson DA, Wasson DB. Synthesis of 2',3'-dideoxynucleosides by enzymatic trans-glycosylation. Biochemical and Biophysical Research Communications. 155: 829-34. PMID 3262341 DOI: 10.1016/S0006-291X(88)80570-9  0.301
1988 Fong S, Chen PP, Crowley JJ, Silverman GJ, Carson DA. Idiotypic characteristics of rheumatoid factors. Scandinavian Journal of Rheumatology. Supplement. 75: 58-65. PMID 3149008 DOI: 10.3109/03009748809096742  0.329
1988 Fong S, Chen PP, Crowley JJ, Silverman GJ, Carson DA. Idiotypes and the structural diversity of human rheumatoid factors. Springer Seminars in Immunopathology. 10: 189-201. PMID 3142069 DOI: 10.1007/Bf01857224  0.325
1988 Silverman GJ, Goldfien RD, Chen P, Mageed RA, Jefferis R, Goñi F, Frangione B, Fong S, Carson DA. Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans. The Journal of Clinical Investigation. 82: 469-75. PMID 3136191 DOI: 10.1172/Jci113620  0.324
1988 Kipps TJ, Tomhave E, Chen PP, Carson DA. Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy. The Journal of Experimental Medicine. 167: 840-52. PMID 3127527 DOI: 10.1084/Jem.167.3.840  0.355
1988 Carson DA, Carrera CJ, Wasson DB, Yamanaka H. Programmed cell death and adenine deoxynucleotide metabolism in human lymphocytes Advances in Enzyme Regulation. 27: 395-404. PMID 2907967 DOI: 10.1016/0065-2571(88)90028-3  0.335
1988 Lotz M, Vaughan JH, Carson DA. Effect of neuropeptides on production of inflammatory cytokines by human monocytes. Science (New York, N.Y.). 241: 1218-21. PMID 2457950 DOI: 10.1126/Science.2457950  0.303
1988 Yamanaka H, Penning CA, Carson DA. 181 CHARACTERIZATION OF POLY(ADP-RIBOSE) POLYMERASE WITH HUMAN AUTOANTIBODIES Pediatric Research. 24: 141-141. DOI: 10.1203/00006450-198807000-00205  0.35
1988 Yamanaka H, Carson DA. 180 MODULATION OF DIPHTHAMIDE SYNTHESIS BY METHYLTHIOADENOSINE Pediatric Research. 24: 141-141. DOI: 10.1203/00006450-198807000-00204  0.352
1988 Carson DA, Haertle T, Carrera CJ, Willis EH, Bruce Wasson D, Richman DD. 19 2-HALO-2′,3′-DIDEOXYADENOSINES: METABOLICALLY STABLE DIDEOXYNUCLEOSIDES WITH ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS (HIV) Pediatric Research. 24: 114-114. DOI: 10.1203/00006450-198807000-00043  0.319
1988 Carson DA, Piro LD, Bruce Wasson P, Carrera CJ, Beucler E. 18 POTENT ACTIVITY OF 2-CHLORODEOXYADENOSINE IN CHRONIC LYMPHOCYTIC LEUKEMIA, HAIRY CELL LEUKEMIA, AND AUTOIMMUNE HEMOLYTIC ANEMIA Pediatric Research. 24: 114-114. DOI: 10.1203/00006450-198807000-00042  0.351
1988 Carrera CJ, Yamanaka H, Piro LD, Carson DA. 17 PROFOUND TOXICITY OF DEOXYADENOSINE (dAdo) AND 2-CHLORODEOXYADENOSINE (CdA) TOWARD HUMAN MONOCYTES IN VITRO AND IN VIVO Pediatric Research. 24: 114-114. DOI: 10.1203/00006450-198807000-00041  0.355
1988 Kipps T, Robbins B, Kuster P, Carson D. Autoantibody-associated cross-reactive idiotypes expressed at high frequency in chronic lymphocytic leukemia relative to B-cell lymphomas of follicular center cell origin Blood. 72: 422-428. DOI: 10.1182/Blood.V72.2.422.422  0.366
1987 Carson DA, Chen PP, Kipps TJ, Radoux V, Jirik FR, Goldfien RD, Fox RI, Silverman GJ, Fong S. Idiotypic and genetic studies of human rheumatoid factors Arthritis and Rheumatism. 30: 1321-1325. PMID 3124859 DOI: 10.1002/Art.1780301201  0.358
1987 Kipps TJ, Fong S, Tomhave E, Chen PP, Goldfien RD, Carson DA. High-frequency expression of a conserved kappa light-chain variable-region gene in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 84: 2916-20. PMID 3106980 DOI: 10.1073/Pnas.84.9.2916  0.378
1987 Silverman GJ, Carson DA, Patrick K, Vaughan JH, Fong S. Expression of a germline human kappa chain-associated cross-reactive idiotype after in vitro and in vivo infection with Epstein-Barr virus. Clinical Immunology and Immunopathology. 43: 403-11. PMID 3034457 DOI: 10.1016/0090-1229(87)90150-4  0.364
1987 Yamanaka H, Willis EH, Penning CA, Peebles CL, Tan EM, Carson DA. Human autoantibodies to poly(adenosine diphosphate-ribose) polymerase. The Journal of Clinical Investigation. 80: 900-4. PMID 2442198 DOI: 10.1172/Jci113150  0.348
1987 Carson DA, Chen PP, Fox RI, Kipps TJ, Jirik F, Goldfien RD, Silverman G, Radoux V, Fong S. Rheumatoid factor and immune networks Annual Review of Immunology. 5: 109-126. PMID 2439101 DOI: 10.1146/Annurev.Iy.05.040187.000545  0.388
1987 Rhodes G, Rumpold H, Kurki P, Patrick KM, Carson DA, Vaughan JH. Autoantibodies in infectious mononucleosis have specificity for the glycine-alanine repeating region of the Epstein-Barr virus nuclear antigen Journal of Experimental Medicine. 165: 1026-1040. PMID 2435830 DOI: 10.1084/Jem.165.4.1026  0.338
1987 Silverman GJ, Fong S, Chen PP, Carson DA. Clinical update: Cross-reactive idiotypes and the genetic origin of rheumatoid factors Journal of Clinical Laboratory Analysis. 1: 129-135. DOI: 10.1002/Jcla.1860010121  0.32
1986 Carson DA, Seto S, Wasson DB. Lymphocyte dysfunction after DNA damage by toxic oxygen species. A model of immunodeficiency Journal of Experimental Medicine. 163: 746-751. PMID 3950545 DOI: 10.1084/Jem.163.3.746  0.306
1986 Montgomery JA, Shortnacy AT, Carson DA, Secrist JA. 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)guanine: A metabolically stable cytotoxic analogue of 2′-deoxyguanosine Journal of Medicinal Chemistry. 29: 2389-2392. PMID 3783596 DOI: 10.1021/Jm00161A041  0.312
1986 Dahbo Y, Carson D, Eriksson S. Increased level of ribonucleotide reductase in deoxyadenosine resistant adenosine deaminase deficient human histiocytic lymphoma cells. Advances in Experimental Medicine and Biology. 231-4. PMID 3532701 DOI: 10.1007/978-1-4684-1248-2_35  0.337
1986 Kajander EO, Kubota M, Willis EH, Carson DA. S-adenosylmethionine metabolism as a target for adenosine toxicity. Advances in Experimental Medicine and Biology. 221-6. PMID 3490121 DOI: 10.1007/978-1-4684-1248-2_33  0.306
1986 Iizasa T, Carson DA. Synthesis and release of deoxycytidine by human B and T lymphoblasts. Biochimica Et Biophysica Acta. 888: 249-51. PMID 3488764 DOI: 10.1016/0167-4889(86)90027-3  0.342
1986 Carrera CJ, Willis EH, Chilcote RR, Kubota M, Carson DA. 5'-deoxy-5'-methylthioadenosine phosphorylase deficiency in leukemia: genetics and biochemical aspects Advances in Experimental Medicine and Biology. 195: 643-650. PMID 3094332 DOI: 10.1007/978-1-4684-1248-2_100  0.347
1986 Yamanaka H, Kajander EO, Carson DA. Modulation of diphthamide synthesis by 5'-deoxy-5'-methylthioadenosine in murine lymphoma cells. Biochimica Et Biophysica Acta. 888: 157-62. PMID 3091083 DOI: 10.1016/0167-4889(86)90016-9  0.357
1986 Shlomchik MJ, Nemazee DA, Sato VL, Van Snick J, Carson DA, Weigert MG. Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells. The Journal of Experimental Medicine. 164: 407-27. PMID 3088205 DOI: 10.1084/Jem.164.2.407  0.594
1986 Carson DA, Carrera CJ, Kubota M, Wasson DB, Iizasa T. Genetic analysis of deoxyadenosine toxicity in dividing human lymphoblasts Advances in Experimental Medicine and Biology. 195: 207-211. PMID 3020905 DOI: 10.1007/978-1-4684-1248-2_31  0.329
1986 Carson DA, Freimark BD. Human lymphocyte hybridomas and monoclonal antibodies. Advances in Immunology. 38: 275-311. PMID 3008522 DOI: 10.1016/S0065-2776(08)60009-7  0.375
1986 Seto S, Carrera CJ, Wasson DB, Carson DA. Biochemical basis for deoxyadenosine and 2-chlorodeoxyadenosine toxicity to resting human lymphocytes Advances in Experimental Medicine and Biology. 195: 577-582. PMID 2876594 DOI: 10.1007/978-1-4684-1248-2_90  0.335
1985 Chen PP, Fong S, Hoghten RA, Carson DA. Characterization of an epibody. An antiidiotype that reacts with both the idiotype of rheumatoid factors (RF) and the antigen recognized by RF Journal of Experimental Medicine. 161: 323-331. PMID 3919139 DOI: 10.1084/Jem.161.2.323  0.337
1985 Iizasa T, Carson DA. Differential regulation of polyamine synthesis and transmethylation reactions in methylthioadenosine phosphorylase deficient mammalian cells. Biochimica Et Biophysica Acta. 844: 280-7. PMID 3918584 DOI: 10.1016/0167-4889(85)90128-4  0.326
1985 Fong S, Chen PP, Vaughan JH, Carson DA. Origin and age-associated changes in the expression of a physiologic autoantibody. Gerontology. 31: 236-50. PMID 3876969 DOI: 10.1159/000212707  0.346
1985 Valentine MA, Tsoukas CD, Vaughan JH, Carson DA. Characterization of Epstein-Barr virus-specific T-cell hybridomas derived from infectious mononucleosis. Clinical Immunology and Immunopathology. 37: 56-62. PMID 2992857 DOI: 10.1016/0090-1229(85)90135-7  0.344
1985 Fong S, Gilbertson TA, Hueniken RJ, Singhal SK, Vaughan JH, Carson DA. IgM rheumatoid factor autoantibody and immunoglobulin-producing precursor cells in the bone marrow of humans. Cellular Immunology. 95: 157-72. PMID 2992814 DOI: 10.1016/0008-8749(85)90304-1  0.365
1985 Tsoukas CD, Valentine M, Lotz M, Vaughan JH, Carson DA. The role of the T3 molecular complex on human T lymphocyte-mediated cytotoxicity. Advances in Experimental Medicine and Biology. 184: 365-85. PMID 2931002 DOI: 10.1007/978-1-4684-8326-0_25  0.324
1985 Lotz M, Tsoukas CD, Fong S, Carson DA, Vaughan JH. Regulation of Epstein-Barr virus infection by recombinant interferons. Selected sensitivity to interferon-gamma. European Journal of Immunology. 15: 520-5. PMID 2581792 DOI: 10.1002/Eji.1830150518  0.333
1985 Seto S, Carrera CJ, Kubota M, Wasson DB, Carson DA. Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes Journal of Clinical Investigation. 75: 377-383. PMID 2579098 DOI: 10.1172/Jci111710  0.343
1985 Chen PP, Gõni F, Houghten RA, Fong S, Goldfien R, Vaughan JH, Frangione B, Carson DA. Characterization of human rheumatoid factors with seven antiidiotypes induced by synthetic hypervariable region peptides. The Journal of Experimental Medicine. 162: 487-500. PMID 2410527 DOI: 10.1084/Jem.162.2.487  0.312
1985 Dahbo Y, Carson DA, Eriksson S. INCREASED LEVEL OF RIBONUCLEOTIDE REDUCTASE IN DEOXY ADENOSINE RESISTANT ADENOSINE DEAMINASE DEFICIENT HUMAN HISTIOCYTIC LYMPHOMA CELLS: 44 Pediatric Research. 19: 751-751. DOI: 10.1203/00006450-198507000-00064  0.306
1985 Carson DA, Kajander EO, Kubota M, Willis EH. MECHANISM OF ADENOSINE TOXICITY TO ADENOSINE KINASE DEFICIENT MAMMALIAN CELLS: 30 Pediatric Research. 19: 748-748. DOI: 10.1203/00006450-198507000-00050  0.325
1985 Carson DA, Kubota M, Wasson DB, Willis EH, Iizasa T. GENETIC ANALYSIS OF DEOXYADENOSINE TOXICITY IN DIVIDING HUMAN LYMPHOBLASTS: 29 Pediatric Research. 19: 748-748. DOI: 10.1203/00006450-198507000-00049  0.319
1985 Carrara CJ, Willis EH, Chilcote RR, Kubota M, Carson DA. 5′-DEOXY–5′-METHYLTHIOADENOSINE (MTA) PHOSPHORYLASE DEFICIENCY IN LEUKEMIA: GENETICS AND BIOCHEMICAL ASPECTS: 28 Pediatric Research. 19: 748-748. DOI: 10.1203/00006450-198507000-00048  0.349
1984 Carson DA. Increase in the complement-fixing ability of murine IgG anti-lymphocyte antibodies by addition of monoclonal IgM rheumatoid factors Journal of Immunological Methods. 68: 103-108. PMID 6707475 DOI: 10.1016/0022-1759(84)90140-6  0.327
1984 Iizasa T, Carson DA. Changes in deoxyadenosine production during human lymphocyte mitogenesis. Experimental Cell Research. 151: 264-7. PMID 6607841 DOI: 10.1016/0014-4827(84)90375-6  0.335
1984 Carson DA, Wasson DB, Beutler E. Antileukemic and immunosuppressive activity of 2-chloro-2'-deoxyadenosine. Proceedings of the National Academy of Sciences of the United States of America. 81: 2232-6. PMID 6585795 DOI: 10.1073/Pnas.81.7.2232  0.319
1984 Kamatani N, Kubota M, Willis EH, Frincke LA, Carson DA. 5'-Methylthioadenosine is the major source of adenine in human cells. Advances in Experimental Medicine and Biology. 83-8. PMID 6426269 DOI: 10.1007/978-1-4757-0390-0_18  0.312
1984 Kamatani N, Kubota M, Willis EH, Carson DA. 5'-Methylthioadenosine phosphorylase deficiency in malignant cells: recessive expression of the defective phenotype in intraspecies (mouse X mouse) hybrids. Advances in Experimental Medicine and Biology. 279-83. PMID 6426266 DOI: 10.1007/978-1-4757-0390-0_53  0.32
1984 Carson DA, Wasson DB, Lakow E, Kamatani N. Biochemical basis for lymphocyte dysfunction in adenosine deaminase and purine nucleoside phosphorylase deficiencies. Advances in Experimental Medicine and Biology. 133-9. PMID 6426261 DOI: 10.1007/978-1-4757-0390-0_27  0.362
1984 Carrera CJ, Eddy RL, Shows TB, Carson DA. Assignment of the gene for methylthioadenosine phosphorylase to human chromosome 9 by mouse-human somatic cell hybridization Proceedings of the National Academy of Sciences of the United States of America. 81: 2665-2668. PMID 6425836 DOI: 10.1073/Pnas.81.9.2665  0.332
1984 Kubota M, Carrera CJ, Wasson DB, Carson DA. Deoxynucleoside overproduction in deoxyadenosine-resistant, adenosine deaminase-deficient human histiocytic lymphoma cells Bba - Molecular Cell Research. 804: 37-43. PMID 6372866 DOI: 10.1016/0167-4889(84)90096-X  0.351
1984 Lakow ES, Valentine MA, Vaughan JH, Tsoukas CD, Carson DA. Effects of monoclonal antibodies against lymphocyte surface antigens on interleukin 2 excretion by Epstein-Barr virus-specific human T-cell hybridomas. Cellular Immunology. 85: 67-74. PMID 6325024 DOI: 10.1016/0008-8749(84)90278-8  0.374
1984 Billings PB, Hoch SO, White PJ, Carson DA, Vaughan JH. Antibodies to the Epstein-Barr virus nuclear antigen and to rheumatoid arthritis nuclear antigen identify the same polypeptide. Proceedings of the National Academy of Sciences of the United States of America. 80: 7104-8. PMID 6316343 DOI: 10.1073/Pnas.80.23.7104  0.337
1984 Tsoukas CD, Lambris J, Lotz M, Valentine MA, Vaughan JH, Carson DA. Lymphocyte mitogenesis induced by monoclonal antibodies to the T3 complex. Differential modulation by human IgG. Cellular Immunology. 89: 66-74. PMID 6207944 DOI: 10.1016/0008-8749(84)90198-9  0.371
1984 Carson DA, Fong S. A common idiotope on human rheumatoid factors identified by a hybridoma antibody. Molecular Immunology. 20: 1081-7. PMID 6201726 DOI: 10.1016/0161-5890(83)90116-5  0.325
1984 Chen PP, Fong S, Normansell D, Houghten RA, Karras JG, Vaughan JH, Carson DA. Delineation of a cross-reactive idiotype on human autoantibodies with antibody against a synthetic peptide. The Journal of Experimental Medicine. 159: 1502-11. PMID 6201589 DOI: 10.1084/Jem.159.5.1502  0.3
1984 Chen PP, Houghten RA, Fong S, Rhodes GH, Gilbertson TA, Vaughan JH, Lerner RA, Carson DA. Anti-hypervariable region antibody induced by a defined peptide: an approach for studying the structural correlates of idiotypes. Proceedings of the National Academy of Sciences of the United States of America. 81: 1784-8. PMID 6200884 DOI: 10.1073/Pnas.81.6.1784  0.303
1983 Kamatani N, Willis EH, Carson DA. Selection and characterization of a murine lymphoid cell line partially deficient in S-adenosylhomocysteine hydrolase. Biochimica Et Biophysica Acta. 762: 205-14. PMID 6600937 DOI: 10.1016/0167-4889(83)90072-1  0.306
1982 Sabharwal UK, Vaughan JH, Fong S, Bennett PH, Carson DA, Curd JG. Activation of the classical pathway of complement by rheumatoid factors. Assessment by radioimmunoassay for C4. Arthritis and Rheumatism. 25: 161-7. PMID 7066047 DOI: 10.1002/Art.1780250208  0.323
1982 Pasquali JL, Tsoukas CD, Fong S, Carson DA, Vaughan JH. Effect of levamisole on pokeweed mitogen stimulation of immunoglobulin production in vitro. Immunopharmacology. 3: 289-98. PMID 6976953 DOI: 10.1016/0162-3109(81)90021-7  0.338
1982 Carson DA, Wasson DB, Lakow E, Kamatani N. Possible metabolic basis for the different immunodeficient states associated with genetic deficiencies of adenosine deaminase and purine nucleoside phosphorylase. Proceedings of the National Academy of Sciences of the United States of America. 79: 3848-52. PMID 6808516 DOI: 10.1073/Pnas.79.12.3848  0.369
1982 Kamatani N, Willis EH, Carson DA. Sequential metabolism of 5'-isobutylthioadenosine by methylthioadenosine phosphorylase and purine-nucleoside phosphorylase in viable human cells. Biochemical and Biophysical Research Communications. 104: 1335-42. PMID 6803802 DOI: 10.1016/0006-291X(82)91396-1  0.3
1982 Fong S, Miller JJ, Moore TL, Tsoukas CD, Vaughan JH, Carson DA. Frequencies of Epstein-Barr virus-inducible IgM anti-IgG B lymphocytes in normal children and children with juvenile rheumatoid arthritis. Arthritis and Rheumatism. 25: 959-65. PMID 6288055 DOI: 10.1002/Art.1780250808  0.307
1982 Tsoukas CD, Fox RI, Carson DA, Fong S, Vaughan JH. Molecular interactions in human T-cell-mediated cytotoxicity to Epstein-Barr virus. I. Blocking of effector cell function by monoclonal antibody OKT3. Cellular Immunology. 69: 113-21. PMID 6286147 DOI: 10.1016/0008-8749(82)90055-7  0.376
1982 Kamatani N, Carson DA. Differential cyst(e)ine requirements in human T and B lymphoblastoid cell lines. International Archives of Allergy and Applied Immunology. 68: 84-9. PMID 6281197 DOI: 10.1159/000233071  0.346
1982 Pasquali JL, Fong S, Tsoukas CD, Slovin SF, Vaughan JH, Carson DA. Different populations of rheumatoid factor idiotypes induced by two polyclonal B cell activators, pokeweed mitogen and Epstein--Barr virus. Clinical Immunology and Immunopathology. 21: 184-9. PMID 6271428 DOI: 10.1016/0090-1229(81)90207-5  0.37
1982 Tsoukas CD, Carson DA, Fong S, Slovin SF, Fox RI, Vaughan JH. Lysis of autologous Epstein-Barr virus-infected B cells by cytotoxic T lymphocytes of rheumatoid arthritis patients. Clinical Immunology and Immunopathology. 24: 8-14. PMID 6179673 DOI: 10.1016/0090-1229(82)90083-6  0.389
1981 Fong S, Fox RI, Rose JE, Liu J, Tsoukas CD, Carson DA, Vaughan JH. Solid-phase selection of human T lymphocyte subpopulations using monoclonal antibodies. Journal of Immunological Methods. 46: 153-63. PMID 7031131 DOI: 10.1016/0022-1759(81)90132-0  0.381
1981 Pasquali JL, Fong S, Tsoukas CD, Hench PK, Vaughan JH, Carson DA. Selective lymphocyte deficiency in seronegative rheumatoid arthritis. Arthritis and Rheumatism. 24: 770-3. PMID 6972764 DOI: 10.1002/Art.1780240603  0.334
1981 Kamatani N, Carson DA. Dependence of adenine production upon polyamine synthesis in cultured human lymphoblasts. Biochimica Et Biophysica Acta. 675: 344-50. PMID 6791702 DOI: 10.1016/0304-4165(81)90024-6  0.339
1981 Kamatani N, Nelson-Rees WA, Carson DA. Selective killing of human malignant cell lines deficient in methylthioadenosine phosphorylase, a purine metabolic enzyme. Proceedings of the National Academy of Sciences of the United States of America. 78: 1219-23. PMID 6785752 DOI: 10.1073/Pnas.78.2.1219  0.334
1981 Fong S, Tsoukas CD, Pasquali JL, Fox RI, Rose JE, Raiklen D, Carson DA, Vaughan JH. Fractionation of human lymphocyte subpopulations on immunoglobulin coated Petri dishes. Journal of Immunological Methods. 44: 171-82. PMID 6456310 DOI: 10.1016/0022-1759(81)90344-6  0.374
1981 Fong S, Pasquali JL, Tsoukas CD, Vaughan JH, Carson DA. Age-related restriction of the light chain heterogeneity of anti-IgG antibodies induced by Epstein-Barr virus stimulation of human lymphocytes in vitro. Clinical Immunology and Immunopathology. 18: 344-50. PMID 6265130 DOI: 10.1016/0090-1229(81)90127-6  0.331
1981 Slovin SF, Vaughan JH, Carson DA. Changes in the expression of two Epstein-Barr virus-associated antigens, EBNA and RANA, during the cell cycle of transformed human B lymphoblasts. International Journal of Cancer. 26: 9-12. PMID 6263806 DOI: 10.1002/Ijc.2910260103  0.326
1980 Pasquali JL, Fong S, Tsoukas C, Vaughan JH, Carson DA. Inheritance of immunoglobulin M rheumatoid-factor idiotypes. The Journal of Clinical Investigation. 66: 863-6. PMID 7419724 DOI: 10.1172/Jci109927  0.301
1980 Theofilopoulos AN, Carson DA, Tavassoli M, Slovin SF, Speers WC, Jensen FB, Vaughan JH. Evidence for the presence of receptors for C3 and IgG Fc on human synovial cells. Arthritis and Rheumatism. 23: 1-9. PMID 7352929 DOI: 10.1002/Art.1780230102  0.304
1980 Howell SB, Chu B, Mendelsohn J, Carson DA, Kung FH, Seegmiller JE. Thymidine as a chemotherapeutic agent: pharmacologic, cytokinetic, and biochemical studies in a patient with T-cell acute lymphocytic leukemia. Journal of the National Cancer Institute. 65: 277-84. PMID 6967527 DOI: 10.1093/Jnci/65.2.277  0.534
1980 Catalano MA, Carson DA, Niederman JC, Feorino P, Vaughan JH. Antibody to the rheumatoid arthritis nuclear antigen. Its relationship to in vivo Epstein-Barr virus infection. The Journal of Clinical Investigation. 65: 1238-42. PMID 6245108 DOI: 10.1172/Jci109779  0.317
1979 Carson DA, Kaye J, Matsumoto S, Seegmiller JE, Thompson L. Uniqueness of deoxyribonucleotide metabolism in human malignant T cell lines. Advances in Experimental Medicine and Biology. 122: 381-8. PMID 317570  0.459
1979 Carson DA, Kaye J, Seegmiller JE. Metabolism and toxicity of 9-beta-D-arabinofuranosyladenine in human malignant T cells and B cells in tissue culture. Advances in Experimental Medicine and Biology. 122: 299-307. PMID 317567  0.47
1979 Carson DA, Kaye J, Matsumoto S, Seegmiller JE, Thompson L. Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines. Proceedings of the National Academy of Sciences of the United States of America. 76: 2430-3. PMID 313056 DOI: 10.1073/pnas.76.5.2430  0.485
1978 Carson DA, Kaye J, Seegmiller JE. Differential sensitivity of human leukemic T cell lines and B cell lines to growth inhibition by deoxyadenosine. Journal of Immunology (Baltimore, Md. : 1950). 121: 1726-31. PMID 309480  0.48
1978 Slaughter L, Carson DA, Jensen FC, Holbrook TL, Vaughan JH. In vitro effects of Epstein-Barr virus on peripheral blood mononuclear cells from patients with rheumatoid arthritis and normal subjects. The Journal of Experimental Medicine. 148: 1429-34. PMID 214511 DOI: 10.1084/Jem.148.5.1429  0.335
1978 Willis RC, Carson DA, Seegmiller JE. Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line. Proceedings of the National Academy of Sciences of the United States of America. 75: 3042-4. PMID 210448  0.45
1977 Carson DA, Goldblum R, Keightley R, Seegmiller JE. Immunoreactive adenosine deaminase (ADA) in cultured fibroblasts from patients with combined immunodeficiency disease. Advances in Experimental Medicine and Biology. 76: 463-70. PMID 855722 DOI: 10.1007/978-1-4613-4223-6_58  0.522
1977 Carson DA, Goldblum R, Seegmiller JE. Quantitative immunoassay of adenosine deaminase in combined immunodeficiency disease. Journal of Immunology (Baltimore, Md. : 1950). 118: 270-3. PMID 830750  0.446
1977 Carson DA, Kaye J, Seegmiller JE. Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleoside kinase(s). Proceedings of the National Academy of Sciences of the United States of America. 74: 5677-81. PMID 202960 DOI: 10.1073/Pnas.74.12.5677  0.507
1976 Carson DA, Seegmiller JE. Effect of adenosine deaminase inhibition upon human lymphocyte blastogenesis. The Journal of Clinical Investigation. 57: 274-82. PMID 176177 DOI: 10.1172/JCI108278  0.482
1975 Carson DA, Kulczycki A, Metzger H. Interaction of IgE with rat basophilic leukemia cells. III. Release of intact receptors on cell-free particles. Journal of Immunology (Baltimore, Md. : 1950). 114: 158-60. PMID 1112975  0.473
1974 Carson DA, Metzger H. Interaction of IgE with rat basophilic leukemia cells. IV. Antibody-induced redistribution of IgE receptors. Journal of Immunology (Baltimore, Md. : 1950). 113: 1271-7. PMID 4606677  0.499
1974 Weigert M, Raschke WC, Carson D, Cohn M. Immunochemical analysis of the idiotypes of mouse myeloma proteins with specificity for levan or dextran. The Journal of Experimental Medicine. 139: 137-47. PMID 4128444 DOI: 10.1084/Jem.139.1.137  0.532
1973 Carson D, Weigert M. Immunochemical analysis of the cross-reacting idiotypes of mouse myeloma proteins with anti-dextran activity and normal anti-dextran antibody. Proceedings of the National Academy of Sciences of the United States of America. 70: 235-239. PMID 4119224 DOI: 10.1073/Pnas.70.1.235  0.571
Low-probability matches (unlikely to be authored by this person)
1984 Iizasa T, Kubota M, Carson DA. Modulation of adenine nucleoside excretion and incorporation in adenosine deaminase deficient human lymphoma cells. Biochemical and Biophysical Research Communications. 121: 514-20. PMID 6428410 DOI: 10.1016/0006-291X(84)90212-2  0.299
1992 Saven A, Carrera C, Carson D, Beutler E, Piro L. 2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T- cell lymphoma Blood. 80: 587-592. DOI: 10.1182/Blood.V80.3.587.Bloodjournal803587  0.299
1998 Hori Y, Hori H, Yamada Y, Carrera CJ, Tomonaga M, Kamihira S, Carson DA, Nobori T. The methylthioadenosine phosphorylase gene is frequently co-deleted with the p16INK4a gene in acute type adult T-cell leukemia. International Journal of Cancer. Journal International Du Cancer. 75: 51-6. PMID 9426690 DOI: 10.1002/(Sici)1097-0215(19980105)75:1<51::Aid-Ijc9>3.0.Co;2-0  0.299
1985 Valentine MA, Tsoukas CD, Rhodes G, Vaughan JH, Carson DA. Phytohemagglutinin binds to the 20-kDa molecule of the T3 complex. European Journal of Immunology. 15: 851-4. PMID 3161747 DOI: 10.1002/Eji.1830150821  0.299
2019 Shinchi H, Yamaguchi T, Moroishi T, Yuki M, Wakao M, Hayashi T, Cottam HB, Carson DA, Suda Y. Gold nanoparticles co-immobilized with small molecule toll-like receptor 7 ligand and α-mannose as adjuvants. Bioconjugate Chemistry. PMID 31560198 DOI: 10.1021/Acs.Bioconjchem.9B00560  0.298
1986 Radoux V, Chen PP, Sorge JA, Carson DA. A conserved human germline V(k) gene directly encodes rheumatoid factor light chains Journal of Experimental Medicine. 164: 2119-2124. PMID 3023521 DOI: 10.1084/Jem.164.6.2119  0.298
1992 Albani S, Tuckwell JE, Esparza L, Carson DA, Roudier J. The susceptibility sequence to rheumatoid arthritis is a cross-reactive B cell epitope shared by the Escherichia coli heat shock protein dnaJ and the histocompatibility leukocyte antigen DRB10401 molecule Journal of Clinical Investigation. 89: 327-331. PMID 1370300 DOI: 10.1172/Jci115580  0.298
1993 Saven A, Piro LD, Carrera CJ, Carson DA, Beutler E. Hairy cell leukemia: new understanding of biology and treatment Cancer Treatment and Research. 64: 15-34. PMID 7680875 DOI: 10.1007/978-1-4615-3086-2_2  0.297
1994 Taniguchi A, Kohsaka H, Carson DA. Competitive RT-PCR ELISA: a rapid, sensitive and non-radioactive method to quantitate cytokine mRNA. Journal of Immunological Methods. 169: 101-9. PMID 7510752 DOI: 10.1016/0022-1759(94)90129-5  0.297
1990 Thompson KM, Randen I, Natvig JB, Mageed RA, Jefferis R, Carson DA, Tighe H, Forre O. Human monoclonal rheumatoid factors derived from the polyclonal repertoire of rheumatoid synovial tissue: incidence of cross-reactive idiotopes and expression of VH and V kappa subgroups. European Journal of Immunology. 20: 863-8. PMID 1693338 DOI: 10.1002/Eji.1830200422  0.297
1997 Yang YY, Fischer P, Leu SJC, Olee T, Carson DA, Chen PP. IgG rheumatoid factors isolated by the surface-displaying phage library technique Immunogenetics. 45: 301-310. PMID 9038102 DOI: 10.1007/S002510050209  0.297
1990 Chen PP, Soto-Gil RW, Carson DA. The early expression of some human autoantibody-associated heavy chain variable region genes is controlled by specific regulatory elements. Scandinavian Journal of Immunology. 31: 673-8. PMID 2113307 DOI: 10.1111/J.1365-3083.1990.Tb02818.X  0.296
1983 Slovin SF, Kuberski TT, Carson DA, Catalano MA, Reitz EM, Vaughan JH. Antibodies to Epstein-Barr virus associated antigens in Pima Indians with and without rheumatoid arthritis. Rheumatology International. 3: 65-68. PMID 6312543 DOI: 10.1007/Bf00541146  0.296
1989 Chen PP, Siminovitch KA, Olsen NJ, Erger RA, Carson DA. A highly informative probe for two polymorphic Vh gene regions that contain one or more autoantibody-associated Vh genes. The Journal of Clinical Investigation. 84: 706-10. PMID 2569476 DOI: 10.1172/Jci114218  0.296
1996 Della Ragione F, Takabayashi K, Mastropietro S, Mercurio C, Oliva A, Russo GL, Della Pietra V, Borriello A, Nobori T, Carson DA, Zappia V. Purification and characterization of recombinant human 5'-methylthioadenosine phosphorylase: Definite identification of coding cDNA Biochemical and Biophysical Research Communications. 223: 514-519. PMID 8687427 DOI: 10.1006/Bbrc.1996.0926  0.296
1995 Huang DF, Siminovitch KA, Liu XY, Olee T, Olsen NJ, Berry C, Carson DA, Chen PP. Population and family studies of three disease-related polymorphic genes in systemic lupus erythematosus. The Journal of Clinical Investigation. 95: 1766-72. PMID 7706484 DOI: 10.1172/Jci117854  0.296
1986 Jirik FR, Sorge J, Fong S, Heitzmann JG, Curd JG, Chen PP, Goldfien R, Carson DA. Cloning and sequence determination of a human rheumatoid factor light-chain gene Proceedings of the National Academy of Sciences of the United States of America. 83: 2195-2199. PMID 3083417 DOI: 10.1073/Pnas.83.7.2195  0.295
1991 Wu DJ, Reynolds L, Carson DA, Nobori T. Molecular genetic analysis of chromosome 9p in methylthioadenosine phosphorylase deficient glioma cell lines Advances in Experimental Medicine and Biology. 309: 207-211. PMID 1781369 DOI: 10.1007/978-1-4615-7703-4_47  0.295
2010 Wu C, Leu H, Ma W, Shih A, Carson D, Kulidjian A, Jamieson C. Bioluminescent Monitoring of Microenvironmental Effects on Multiple Myeloma Engraftment In a Humanized Mouse Model Blood. 116: 1927-1927. DOI: 10.1182/Blood.V116.21.1927.1927  0.295
2003 Kyburz D, Pierer M, Rethage J, Seibl R, Carson D. Activation of synovial fibroblasts via Toll-like receptor signaling Arthritis Research & Therapy. 5: 40-40. DOI: 10.1186/Ar841  0.294
1986 Newkirk M, Chen PP, Carson D, Posnett D, Capra JD. Amino acid sequence of a light chain variable region of a human rheumatoid factor of the Wa idiotypic group, in part predicted by its reactivity with antipeptide antibodies. Molecular Immunology. 23: 239-44. PMID 3086710 DOI: 10.1016/0161-5890(86)90049-0  0.294
1980 Kaplan RA, Curd JG, Deheer DH, Carson DA, Pangburn MK, Müller-Eberhard HJ, Vaughan JH. Metabolism of C4 and factor B in rheumatoid arthritis. Relation to rheumatoid factor. Arthritis and Rheumatism. 23: 911-20. PMID 6967727 DOI: 10.1002/Art.1780230806  0.293
1987 Richman DD, Kornbluth RS, Carson DA. Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages Journal of Experimental Medicine. 166: 1144-1149. PMID 2821152 DOI: 10.1084/Jem.166.4.1144  0.293
2000 Sen M, Lauterbach K, El-Gabalawy H, Firestein GS, Corr M, Carson DA. Expression and function of wingless and frizzled homologs in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America. 97: 2791-6. PMID 10688908 DOI: 10.1073/Pnas.050574297  0.292
1992 Nobori T, Reynolds L, Orvis L, Wu D, Carson DA. A polymerase chain reaction-based method for isolation of gene-specific sequences from the interferon-alpha gene cluster. Analytical Biochemistry. 205: 42-6. PMID 1443559 DOI: 10.1016/0003-2697(92)90576-S  0.292
1987 Chen PP, Fong S, Carson DA. The use of defined peptides in characterizing idiotypes International Reviews of Immunology. 2: 419-432. PMID 3153458 DOI: 10.3109/08830188709044765  0.29
2000 Suh SI, Pyun HY, Cho JW, Baek WK, Park JB, Kwon T, Park JW, Suh MH, Carson DA. 5-Aza-2'-deoxycytidine leads to down-regulation of aberrant p16INK4A RNA transcripts and restores the functional retinoblastoma protein pathway in hepatocellular carcinoma cell lines. Cancer Letters. 160: 81-8. PMID 11098088 DOI: 10.1016/S0304-3835(00)00566-8  0.288
1988 Piro L, Carrera C, Beutler E, Carson D. 2-Chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukemia Blood. 72: 1069-1073. DOI: 10.1182/Blood.V72.3.1069.Bloodjournal7231069  0.288
1993 Raz E, Watanabe A, Baird SM, Eisenberg RA, Parr TB, Lotz M, Kipps TJ, Carson DA. Systemic immunological effects of cytokine genes injected into skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 90: 4523-7. PMID 8506293 DOI: 10.1073/Pnas.90.10.4523  0.288
1983 Carson DA, Willis EH, Kamatani N. Metabolism to methionine and growth stimulation by 5'-methylthioadenosine and 5'-methylthioinosine in mammalian cells. Biochemical and Biophysical Research Communications. 112: 391-7. PMID 6601949 DOI: 10.1016/0006-291X(83)91476-6  0.288
1992 Kay AC, Saven A, Carrera CJ, Carson DA, Thurston D, Beutler E, Piro LD. 2-Chlorodeoxyadenosine treatment of low-grade lymphomas. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 10: 371-7. PMID 1346801 DOI: 10.1200/Jco.1992.10.3.371  0.287
1998 Kohsaka H, Carson DA, Miyasaka N. Formation of peripheral immunoreceptor repertoire for antigens: potential relationship to the pathogenesis of rheumatoid arthritis. Arthritis and Rheumatism. 41: 1911-8. PMID 9811044 DOI: 10.1002/1529-0131(199811)41:11<1911::Aid-Art4>3.0.Co;2-S  0.287
1983 Kamatani N, Willis EH, McGarrity GJ, Carson DA. Putrescine dependent growth of mycoplasma infected mammalian cells. Journal of Cellular Physiology. 114: 16-20. PMID 6826657 DOI: 10.1002/Jcp.1041140104  0.287
1988 Lotz M, Jirik F, Kabouridis P, Tsoukas C, Hirano T, Kishimoto T, Carson DA. B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes Journal of Experimental Medicine. 167: 1253-1258. PMID 3127525 DOI: 10.1084/Jem.167.3.1253  0.287
2001 Genini D, Sheeter D, Rought S, Zaunders JJ, Susin SA, Kroemer G, Richman DD, Carson DA, Corbeil J, Leoni LM. HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 5-6. PMID 11099484 DOI: 10.1096/Fj.00-0336Fje  0.287
1987 Chen PP, Robbins DL, Jirik FR, Kipps TJ, Carson DA. Isolation and characterization of a light chain variable region gene for human rheumatoid factors. The Journal of Experimental Medicine. 166: 1900-5. PMID 3119763 DOI: 10.1084/Jem.166.6.1900  0.286
2002 Kyburz D, Rethage J, Seibl R, Michel B, Carson D. Bacterial peptidoglycan stimulates integrin expression and MMP production of synovial fibroblasts Arthritis Research & Therapy. 4: 31-31. DOI: 10.1186/Ar472  0.286
1989 Guerne PA, Zuraw BL, Vaughan JH, Carson DA, Lotz M. Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis. The Journal of Clinical Investigation. 83: 585-92. PMID 2464001 DOI: 10.1172/Jci113921  0.285
2020 Shi G, Wu CCN, Darmadi S, Wang Z, Carson D, Liu Y. Abstract 489: Buoyant targeted microbubble technology provides efficient and superior quality of hematopoietic stem cells isolated from umbilical cord blood Cancer Research. 80: 489-489. DOI: 10.1158/1538-7445.Am2020-489  0.285
1994 Deftos M, Olee T, Carson DA, Chen PP. Defining the genetic origins of three rheumatoid synovium-derived IgG rheumatoid factors Journal of Clinical Investigation. 93: 2545-2553. PMID 8200991 DOI: 10.1172/Jci117265  0.285
1988 Bruce Wasson P, Yamanaka H, Carson DA. 171 UTILIZATION OF 2′-DEOXYNAD FOR ADP-RIBOSE TRANSFER REACTIONS Pediatric Research. 24: 139-139. DOI: 10.1203/00006450-198807000-00195  0.285
1978 Carson DA, Lawrance S. Light chain heterogeneity of 19S and 7S anti-gamma-globulins in rheumatoid arthritis and subacute bacterial endocarditis. Arthritis and Rheumatism. 21: 438-40. PMID 418786 DOI: 10.1002/Art.1780210406  0.284
1993 Lu EW, Deftos M, Olee T, Huang DF, Soto-Gil RW, Carson DA, Chen PP. Generation and molecular analyses of two rheumatoid synovial fluid-derived IgG rheumatoid factors Arthritis and Rheumatism. 36: 927-937. PMID 7916590 DOI: 10.1002/Art.1780360709  0.284
1992 Carson DA. Genetic factors in the etiology and pathogenesis of autoimmunity Faseb Journal. 6: 2800-2805. PMID 1634042 DOI: 10.1096/Fasebj.6.10.1634042  0.284
2014 Carson DA, Lakow E, Wasson DB, Kamatani N. Lymphocyte dysfunction caused by deficiencies in purine metabolism. Immunology Today. 2: 234-8. PMID 25290650 DOI: 10.1016/0167-5699(81)90010-4  0.284
2018 Wu C, Ghia EM, Lao F, Pu M, Messer K, Rassenti LZ, Kipps TJ, Carson DA, Choi MY. Tecfidera Modulates Activation of Malignant B-Cells: Correlative Analysis from a Phase 1 Clinical Trial in Patients with Chronic Lymphocytic Leukemia Blood. 132: 3143-3143. DOI: 10.1182/Blood-2018-99-119292  0.284
2009 Jin G, Lu D, Yao S, Wu CC, Liu JX, Carson DA, Cottam HB. Amide derivatives of ethacrynic acid: synthesis and evaluation as antagonists of Wnt/beta-catenin signaling and CLL cell survival. Bioorganic & Medicinal Chemistry Letters. 19: 606-9. PMID 19121941 DOI: 10.1016/J.Bmcl.2008.12.067  0.284
1982 McGarrity GJ, Carson DA. Adenosine phosphorylase-mediated nucleoside toxicity. Application towards the detection of mycoplasmal infection in mammalian cell cultures. Experimental Cell Research. 139: 199-205. PMID 6806107 DOI: 10.1016/0014-4827(82)90333-0  0.283
1979 Dunne JV, Carson DA, Spiegelberg HL, Alspaugh MA, Vaughan JH. IgA rheumatoid factor in the sera and saliva of patients with rheumatoid arthritis and Sjögren's syndrome. Annals of the Rheumatic Diseases. 38: 161-5. PMID 443882 DOI: 10.1136/Ard.38.2.161  0.282
1989 Nobori T, Yamanaka H, Carson DA. Poly(ADP-ribose) polymerase inhibits DNA synthesis initiation in the absence of NAD. Biochemical and Biophysical Research Communications. 163: 1113-8. PMID 2506850 DOI: 10.1016/0006-291X(89)92336-X  0.282
2000 Schmid M, Sen M, Rosenbach MD, Carrera CJ, Friedman H, Carson DA. A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer. Oncogene. 19: 5747-54. PMID 11126361 DOI: 10.1038/Sj.Onc.1203942  0.281
1990 Kouri T, Crowley J, Aho K, Palosuo T, Isomäki H, von Essen R, Heliövaara M, Carson D, Vaughan JH. Occurrence of two germline-related rheumatoid factor idiotypes in rheumatoid arthritis and in non-rheumatoid seropositive individuals. Clinical and Experimental Immunology. 82: 250-6. PMID 2122932 DOI: 10.1111/J.1365-2249.1990.Tb05435.X  0.281
2005 Lu D, Cottam HB, Corr M, Carson DA. Repression of beta-catenin function in malignant cells by nonsteroidal antiinflammatory drugs. Proceedings of the National Academy of Sciences of the United States of America. 102: 18567-71. PMID 16352713 DOI: 10.1073/Pnas.0509316102  0.279
1991 Kekow J, Wachsman W, McCutchan JA, Gross WL, Zachariah M, Carson DA, Lotz M. Transforming growth factor-beta and suppression of humoral immune responses in HIV infection. The Journal of Clinical Investigation. 87: 1010-6. PMID 1999481 DOI: 10.1172/Jci115059  0.279
1996 Kohsaka H, Carson DA, Rassenti LZ, Ollier WER, Chen PP, Kipps TJ, Miyasaka N. The human immunoglobulin VH gene repertoire is genetically controlled and unaltered by chronic autoimmune stimulation Journal of Clinical Investigation. 98: 2794-2800. PMID 8981926 DOI: 10.1172/Jci119106  0.279
1993 Kohsaka H, Taniguchi A, Richman DD, Carson DA. Microtiter format gene quantification by covalent capture of competitive PCR products: Application to HIV-1 detection Nucleic Acids Research. 21: 3469-3472. PMID 8346024 DOI: 10.1093/Nar/21.15.3469  0.279
1997 Tran PT, Hori H, Hori Y, Okumura K, Kagotani K, Taguchi H, Carson DA, Nobori T. Molecular cloning of the human methylthioadenosine phosphorylase processed pseudogene and localization to 3q28. Gene. 186: 263-9. PMID 9074505 DOI: 10.1016/S0378-1119(96)00718-4  0.279
2008 Daniels GA, Chan M, Messmer D, Bui J, Carson D. Epigenetic modulation enhances vaccine efficacy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 14651. PMID 27949503 DOI: 10.1200/Jco.2008.26.15_Suppl.14651  0.279
2001 Sen M, Chamorro M, Reifert J, Corr M, Carson DA. Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation. Arthritis and Rheumatism. 44: 772-81. PMID 11315916 DOI: 10.1002/1529-0131(200104)44:4<772::Aid-Anr133>3.0.Co;2-L  0.278
1986 Lotz M, Tsoukas CD, Robinson CA, Dinarello CA, Carson DA, Vaughan JH. Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies. The Journal of Clinical Investigation. 78: 713-21. PMID 3091636 DOI: 10.1172/Jci112631  0.278
1991 Roudier J, Sette A, Lamont A, Albani S, Karras JG, Carson DA. Tolerance to a self peptide from the third hypervariable region of the Es beta chain. Implications for molecular mimicry models of autoimmune disease. European Journal of Immunology. 21: 2063-7. PMID 1889457 DOI: 10.1002/Eji.1830210914  0.277
1988 Silverman GJ, Goñi F, Fernandez J, Chen PP, Frangione B, Carson DA. Distinct patterns of heavy chain variable region subgroup use by human monoclonal autoantibodies of different specificity. The Journal of Experimental Medicine. 168: 2361-6. PMID 3143801 DOI: 10.1084/Jem.168.6.2361  0.277
1998 Schmid M, Malicki D, Nobori T, Rosenbach MD, Campbell K, Carson DA, Carrera CJ. Homozygous deletions of methylthioadenosine phosphorylase (MTAP) are more frequent than p16INK4A (CDKN2) homozygous deletions in primary non-small cell lung cancers (NSCLC). Oncogene. 17: 2669-75. PMID 9840931 DOI: 10.1038/Sj.Onc.1202205  0.277
2005 Liu Y, Rassenti LZ, Shen Z, Chuang H, Briggs SP, Kipps TJ, Carson D. Differential Expression Profile of the Proteome and Transcriptome in Aggressive and Indolent Chronic Lymphocytic Leukemia. Blood. 106: 2101-2101. DOI: 10.1182/Blood.V106.11.2101.2101  0.276
1987 Lotz M, Carson DA, Vaughan JH. Substance P Activation of Rheumatoid Synoviocytes: Neural Pathway in Pathogenesis of Arthritis Science. 235: 893-895. PMID 2433770 DOI: 10.1126/Science.2433770  0.273
2009 Lu D, Liu JX, Endo T, Zhou H, Yao S, Willert K, Schmidt-Wolf IG, Kipps TJ, Carson DA. Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway. Plos One. 4: e8294. PMID 20011538 DOI: 10.1371/Journal.Pone.0008294  0.273
1985 Seto S, Carrera CJ, Wasson DB, Carson DA. BIOCHEMICAL BASIS FOR DEOXYADENOSINE AND 2-CHLORODEOXYADENOSINE TOXICITY TO BESTING HDMAN LYMPHOCYTES: 187 Pediatric Research. 19: 775-775. DOI: 10.1203/00006450-198507000-00207  0.272
2004 Hedvat M, Jain A, Carson DA, Leoni LM, Huang G, Holden S, Lu D, Corr M, Fox W, Agus DB. Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARgamma. Cancer Cell. 5: 565-74. PMID 15193259 DOI: 10.1016/J.Ccr.2004.05.014  0.271
1990 Chen PP, Silverman GJ, Liu M, Carson DA. Idiotypic and molecular characterization of human rheumatoid factors. Chemical Immunology. 48: 63-81. DOI: 10.1159/000318933  0.271
2010 Lu D, Carson DA. Repression of beta-catenin signaling by PPAR gamma ligands. European Journal of Pharmacology. 636: 198-202. PMID 20303941 DOI: 10.1016/J.Ejphar.2010.03.010  0.27
1993 Kobayashi R, Rassenti LZ, Meisenholder G, Carson DA, Kipps TJ. Autoantigen inhibits apoptosis of a human B cell leukemia that produces pathogenic rheumatoid factor Journal of Immunology. 151: 7273-7283. PMID 7505024  0.27
2015 Smith EN, Ghia EM, DeBoever CM, Rassenti LZ, Jepsen K, Yoon KA, Matsui H, Rozenzhak S, Alakus H, Shepard PJ, Dai Y, Khosroheidari M, Bina M, Gunderson KL, Messer K, ... ... Carson DA, et al. Genetic and epigenetic profiling of CLL disease progression reveals limited somatic evolution and suggests a relationship to memory-cell development. Blood Cancer Journal. 5: e303. PMID 25860294 DOI: 10.1038/Bcj.2015.14  0.269
1995 Eibschutz B, Baird SM, Weisman MH, Amox DG, Spellman M, Piacquadio D, Carrera CJ, Carson DA. Oral 2-chlorodeoxyadenosine in psoriatic arthritis: A preliminary report Arthritis and Rheumatism. 38: 1604-1609. PMID 7488281 DOI: 10.1002/Art.1780381112  0.268
1992 Lu EW, Deftos M, Tighe H, Carson DA, Chen PP. Generation and characterization of two monoclonal self-associating IgG rheumatoid factors from a rheumatoid synovium. Arthritis and Rheumatism. 35: 101-5. PMID 1731807 DOI: 10.1002/Art.1780350115  0.268
2004 Adachi S, Leoni LM, Carson DA, Nakahata T. Apoptosis induced by molecular targeting therapy in hematological malignancies. Acta Haematologica. 111: 107-23. PMID 14646349 DOI: 10.1159/000074490  0.267
1986 Fong S, Chen PP, Fox RI, Goldfien RD, Silverman GJ, Radoux V, Jirik F, Vaughan JH, Carson DA. Rheumatoid factors in human autoimmune disease: their origin, development and function Pathology and Immunopathology Research. 5: 305-316. PMID 3110754 DOI: 10.1159/000157024  0.267
1984 Rhodes G, Houghten R, Taulane JP, Carson D, Vaughan J. The immune response to Epstein-Barr nuclear antigen: conformational and structural features of antibody binding to synthetic peptides. Molecular Immunology. 21: 1047-1054. PMID 6096700 DOI: 10.1016/0161-5890(84)90114-7  0.266
2000 Carson DA. Arthritis Research. 1: S11. DOI: 10.1186/Ar25  0.266
1993 Yamanaka H, Hakoda M, Kamatani N, Kashiwazaki S, Carson DA. Formation of DNA strand breaks by D-penicillamine and bucillamine in human lymphocytes Immunopharmacology. 26: 113-118. PMID 8282535 DOI: 10.1016/0162-3109(93)90003-9  0.265
1986 McGarrity GJ, Kotani H, Carson D. Comparative studies to determine the efficiency of 6 methylpurine deoxyriboside to detect cell culture mycoplasmas. In Vitro Cellular & Developmental Biology – Plant. 22: 301-304. PMID 2428802 DOI: 10.1007/Bf02623401  0.264
1999 Brat DJ, James CD, Jedlicka AE, Connolly DC, Chang E, Castellani RJ, Schmid M, Schiller M, Carson DA, Burger PC. Molecular genetic alterations in radiation-induced astrocytomas. The American Journal of Pathology. 154: 1431-8. PMID 10329596 DOI: 10.1016/S0002-9440(10)65397-7  0.261
2000 Suh SI, Cho JW, Baek WK, Suh MH, Carson DA. Lack of mutation at p16INK4A gene but expression of aberrant p16INK4A RNA transcripts in human ovarian carcinoma. Cancer Letters. 153: 175-82. PMID 10779647 DOI: 10.1016/S0304-3835(00)00369-4  0.261
1999 Carson DA, Haneji N. Fighting arthritis with a senescence gene. Nature Medicine. 5: 731-2. PMID 10395310 DOI: 10.1038/10447  0.26
2016 Wang Z, Li B, Zhou L, Yu S, Su Z, Song J, Sun Q, Sha O, Wang X, Jiang W, Willert K, Wei L, Carson DA, Lu D. Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799526 DOI: 10.1073/Pnas.1616336113  0.256
1987 Willis EH, Carson DA, Shultz LD. Adenosine deaminase activity in recipients of bone marrow from immunodeficient mice homozygous for the wasted mutation. Biochemical and Biophysical Research Communications. 145: 581-5. PMID 3297058 DOI: 10.1007/978-1-4684-5676-9_31  0.256
2019 Wang Z, Zhou L, Xiong Y, Yu S, Li H, Fan J, Li F, Su Z, Song J, Sun Q, Liu SS, Xia Y, Zhao L, Li S, Guo F, ... ... Carson DA, et al. Salinomycin exerts anti-colorectal cancer activity by targeting the β-catenin/TCF complex. British Journal of Pharmacology. PMID 31236922 DOI: 10.1111/Bph.14770  0.254
1999 Kyburz D, Corr M, Brinson DC, Von Damm A, Tighe H, Carson DA. Human rheumatoid factor production is dependent on CD40 signaling and autoantigen. Journal of Immunology (Baltimore, Md. : 1950). 163: 3116-22. PMID 10477577  0.254
1994 Kohsaka H, Carson DA. Solid-phase polymerase chain reaction Journal of Clinical Laboratory Analysis. 8: 452-455. PMID 7869187 DOI: 10.1002/Jcla.1860080619  0.253
1981 Rosenbaum JT, Theofilopoulos AN, McDevitt HO, Pereira AB, Carson D, Calin A. Presence of circulation immune complexes in Reiter's syndrome and ankylosing spondylitis. Clinical Immunology and Immunopathology. 18: 291-7. PMID 7008993 DOI: 10.1016/0090-1229(81)90036-2  0.253
1995 Wicks IP, Howell ML, Hancock T, Kohsaka H, Olee T, Carson DA. Bacterial lipopolysaccharide copurifies with plasmid DNA: Implications for animal models and human gene therapy Human Gene Therapy. 6: 317-323. PMID 7779915 DOI: 10.1089/Hum.1995.6.3-317  0.252
1997 Carson DA, Raz E. Oligonucleotide adjuvants for T helper 1 (Th1)-specific vaccination. The Journal of Experimental Medicine. 186: 1621-2. PMID 9411016 DOI: 10.1084/Jem.186.10.1621  0.251
2005 Ohata J, Zvaifler NJ, Nishio M, Boyle DL, Kalled SL, Carson DA, Kipps TJ. Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines. Journal of Immunology (Baltimore, Md. : 1950). 174: 864-70. PMID 15634908  0.25
1991 Nobori T, Hexdall LE, Carson DA. A polymorphic region defined by pCN2 (the 3' nontranslated region of N-ras) maps to chromosome 9cen-p12. Human Genetics. 87: 433-7. PMID 1879830 DOI: 10.1007/Bf00197163  0.249
1991 Saven A, Carrera CJ, Carson DA, Beutler E, Piro LD. 2-chlorodeoxyadenosine treatment of refractory chronic lymphocytic leukemia Leukemia and Lymphoma. 5: 133-138. DOI: 10.3109/10428199109103394  0.248
1983 Carson D, Wasson D, Taetle R, Yu A. Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes Blood. 62: 737-743. DOI: 10.1182/blood.v62.4.737.737  0.247
1983 Carson D, Wasson D, Taetle R, Yu A. Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes Blood. 62: 737-743. DOI: 10.1182/blood.V62.4.737.bloodjournal624737  0.247
1988 Roudier J, Rhodes G, Petersen J, Vaughan JH, Carson DA. The Epstein-Barr virus glycoprotein gp110, a molecular link between HLA DR4, HLA DR1, and rheumatoid arthritis. Scandinavian Journal of Immunology. 27: 367-71. PMID 2452474 DOI: 10.1111/J.1365-3083.1988.Tb02359.X  0.246
2003 Silverman GJ, Carson DA. Roles of B cells in rheumatoid arthritis. Arthritis Research & Therapy. 5: S1-6. PMID 15180890 DOI: 10.1186/ar1010  0.244
1982 Kamatani N, Yu A, Carson D. Deficiency of methylthioadenosine phosphorylase in human leukemic cells in vivo Blood. 60: 1387-1391. DOI: 10.1182/blood.V60.6.1387.bloodjournal6061387  0.243
1988 Kipps T, Robbins B, Kuster P, Carson D. Autoantibody-associated cross-reactive idiotypes expressed at high frequency in chronic lymphocytic leukemia relative to B-cell lymphomas of follicular center cell origin Blood. 72: 422-428. DOI: 10.1182/blood.v72.2.422.422  0.243
2005 Holderbaum D, Malvitz T, Ciesielski CJ, Carson D, Corr MP, Moskowitz RW. A newly described hereditary cartilage debonding syndrome Arthritis & Rheumatism. 52: 3300-3304. PMID 16200603 DOI: 10.1002/Art.21352  0.243
1993 Kipps TJ, Carson DA. Autoantibodies in chronic lymphocytic leukemia and related systemic autoimmune diseases Blood. 81: 2475-2487. PMID 8490163 DOI: 10.1182/Blood.V81.10.2475.Bloodjournal81102475  0.242
2022 Saito T, Shukla NM, Sato-Kaneko F, Sako Y, Hosoya T, Yao S, Lao FS, Messer K, Pu M, Chan M, Chu PJ, Cottam HB, Hayashi T, Carson DA, Corr M. Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity. Acs Chemical Biology. PMID 34985883 DOI: 10.1021/acschembio.1c00883  0.242
1997 Perry A, Nobori T, Ru N, Anderl K, Borell TJ, Mohapatra G, Feuerstein BG, Jenkins RB, Carson DA. Detection of p16 gene deletions in gliomas: A comparison of fluorescence in situ hybridization (FISH) versus quantitative PCR Journal of Neuropathology and Experimental Neurology. 56: 999-1008. PMID 9291941 DOI: 10.1097/00005072-199709000-00005  0.242
1992 Soto-Gil RW, Olee T, Klink BK, Kenny TP, Robbins DL, Carson DA, Chen PP. A systematic approach to defining the germline gene counterparts of a mutated autoantibody from a patient with rheumatoid arthritis. Arthritis and Rheumatism. 35: 356-63. PMID 1339266 DOI: 10.1002/Art.1780350316  0.241
2008 Fukuda T, Chen L, Endo T, Tang L, Lu D, Castro JE, Widhopf GF, Rassenti LZ, Cantwell MJ, Prussak CE, Carson DA, Kipps TJ. Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a. Proceedings of the National Academy of Sciences of the United States of America. 105: 3047-52. PMID 18287027 DOI: 10.1073/pnas.0712148105  0.24
1988 Chen PP, Fong S, Goni F, Silverman GJ, Fox RI, Liu MF, Frangione B, Carson DA. Cross-reacting idiotypes on cryoprecipitating rheumatoid factor. Springer Seminars in Immunopathology. 10: 35-55. PMID 3137675 DOI: 10.1007/Bf02054022  0.239
1996 Albani S, Carson DA. A multistep molecular mimicry hypothesis for the pathogenesis of rheumatoid arthritis Immunology Today. 17: 466-470. PMID 8908811 DOI: 10.1016/0167-5699(96)20029-G  0.238
1987 LOTZ M, CARSON DA, VAUGHAN JH. Substance P Activation of Rheumatoid Synoviocytes Obstetrical & Gynecological Survey. 42: 570-571. DOI: 10.1097/00006254-198709000-00014  0.237
1985 Carson DA, Iizasa T, Seto S, Carrera CJ, Kubota M, Willis EH, Wasson DB, Kajander O. Metabolic basis for immune dysfunction in adenosine deaminase deficiency. Annals of the New York Academy of Sciences. 451: 34-41. PMID 3878120 DOI: 10.1111/J.1749-6632.1985.Tb27094.X  0.237
2010 Wu RP, Hayashi T, Cottam HB, Jin G, Yao S, Wu CC, Rosenbach MD, Corr M, Schwab RB, Carson DA. Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 107: 7479-84. PMID 20368435 DOI: 10.1073/pnas.1002890107  0.237
1992 Carrera CJ, Piro LD, Saven A, Beutler E, Terai C, Carson DA. 2-Chlorodeoxyadenosine chemotherapy triggers programmed cell death in normal and malignant lymphocytes. Advances in Experimental Medicine and Biology. 15-8. PMID 1686349 DOI: 10.1007/978-1-4899-2638-8_3  0.235
1996 Levy SG, Wasson DB, Carson DA, Cottam HB. Synthesis of 2-chloro-2'-5'-dideoxy-5'-difluoromethylphosphinyladenosine: A nonhydrolyzable isosteric, isopolar analog of 2-chlorodeoxyadenosine monophosphate Synthesis. 843-846. DOI: 10.1055/S-1996-4314  0.234
2018 Su Z, Song J, Wang Z, Zhou L, Xia Y, Yu S, Sun Q, Liu SS, Zhao L, Li S, Wei L, Carson DA, Lu D. Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. PMID 30038030 DOI: 10.1073/Pnas.1802422115  0.232
1982 Slovin SF, Frisman DM, Tsoukas CD, Royston I, Baird SM, Wormsley SB, Carson DA, Vaughan JH. Membrane antigen on Epstein--Barr virus-infected human B cells recognized by a monoclonal antibody. Proceedings of the National Academy of Sciences of the United States of America. 79: 2649-53. PMID 6283539 DOI: 10.1073/pnas.79.8.2649  0.232
1985 Carson DA, Kubota M, Lizasa T. Infection and Immunity: Mechanisms of Immunodeficiency in Inborn Errors of Purine Metabolism Pediatrics International. 27: 40-45. DOI: 10.1111/J.1442-200X.1985.Tb00613.X  0.229
1988 Mageed RA, Carson DA, Jefferis R. Immunogenic and antigenic epitopes of immunoglobulins. XXIII. Idiotypy and molecular specificity of human rheumatoid factors: analysis of cross-reactive idiotype of rheumatoid factor paraproteins from the Wa idiotype group in relation to their IgG subclass specificity. Scandinavian Journal of Immunology. 28: 233-40. PMID 2457937 DOI: 10.1111/j.1365-3083.1988.tb02436.x  0.228
1989 Nobori T, Hexdall LE, Carson DA. cDNA sequence of human ribosomal protein L31. Nucleic Acids Research. 17: 7105. PMID 2780320 DOI: 10.1093/Nar/17.17.7105  0.227
1982 Carson DA, Pasquali JL, Tsoukas CD, Fong S, Slovin SF, Lawrance SK, Slaughter L, Vaughan JH. Physiology and pathology of rheumatoid factors. Springer Seminars in Immunopathology. 4: 161-79. PMID 7323953 DOI: 10.1007/Bf01857093  0.227
1989 Carrera CJ, Yamanaka H, Piro LD, Lotz M, Carson DA. Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo Advances in Experimental Medicine and Biology. 253: 219-225. PMID 2575348 DOI: 10.1007/978-1-4684-5676-9_33  0.227
1988 Willts EH, Shultz LD, Carson DA. 173 ADENOSINE DEAMINASE ACTIVITY IN RECIPIENTS OF BONE MARROU FROM IMMUNODEFICIENT MICE HOMOZYGOUS FOR THE WASTED MUTATION Pediatric Research. 24: 140-140. DOI: 10.1203/00006450-198807000-00197  0.227
2014 Smith EN, Jepsen K, Khosroheidari M, Rassenti LZ, D'Antonio M, Ghia EM, Carson DA, Jamieson CH, Kipps TJ, Frazer KA. Biased estimates of clonal evolution and subclonal heterogeneity can arise from PCR duplicates in deep sequencing experiments. Genome Biology. 15: 420. PMID 25103687 DOI: 10.1186/S13059-014-0420-4  0.225
1989 LOTZ M, ZURAW BL, CARSON DA, JIRIK FR. Hepatocytes Produce Interleukin‐6 Annals of the New York Academy of Sciences. 557: 509-511. DOI: 10.1111/J.1749-6632.1989.Tb24048.X  0.225
1993 Beutler E, Carson DA. 2-Chlorodeoxyadenosine: Hairy cell leukemia takes a surprising turn Blood Cells. 19: 559-568. PMID 8018939  0.224
1996 Kohsaka H, Nanki T, Ollier WE, Miyasaka N, Carson DA. Influence of the rheumatoid arthritis-associated shared epitope on T-cell receptor repertoire formation Proceedings of the Association of American Physicians. 108: 323-328. PMID 8863346  0.224
1981 Carson DA, Wasson DB, Kaye J, Ullman B, Martin DW, Robins RK, Montgomery JA. Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo. Proceedings of the National Academy of Sciences of the United States of America. 77: 6865-9. PMID 6256765 DOI: 10.1073/Pnas.77.11.6865  0.222
1990 Carson DA, Diamond J. In Appreciation of William J. Koopman, MD editor, arthritis and rheumatism, 1985–90 Arthritis & Rheumatism. 33: 909-909. DOI: 10.1002/Art.1780330622  0.221
2010 Kim Y, Alpmann P, Blaum-Feder S, Krämer S, Endo T, Lu D, Carson D, Schmidt-Wolf IG. In vivo efficacy of griseofulvin against multiple myeloma. Leukemia Research. 35: 1070-3. PMID 21112630 DOI: 10.1016/j.leukres.2010.10.008  0.221
2018 Sato-Kaneko F, Wang X, Yao S, Hosoya T, Lao FS, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Carson DA, Corr M, Hayashi T. Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy. Biomed Research International. 2018: 8091283. PMID 30406141 DOI: 10.1155/2018/8091283  0.218
2003 Lee J, Chuang TH, Redecke V, She L, Pitha PM, Carson DA, Raz E, Cottam HB. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proceedings of the National Academy of Sciences of the United States of America. 100: 6646-51. PMID 12738885 DOI: 10.1073/pnas.0631696100  0.217
1990 Silverman GJ, Schrohenloher RE, Accavitti MA, Koopman WJ, Carson DA. Structural characterization of the second major cross-reactive idiotype group of human rheumatoid factors. Association with the VH4 gene family. Arthritis and Rheumatism. 33: 1347-60. PMID 2403399 DOI: 10.1002/art.1780330907  0.214
2015 Choi MY, Widhopf GF, Wu CC, Cui B, Lao F, Sadarangani A, Cavagnaro J, Prussak C, Carson DA, Jamieson C, Kipps TJ. Pre-clinical Specificity and Safety of UC-961, a First-In-Class Monoclonal Antibody Targeting ROR1. Clinical Lymphoma, Myeloma & Leukemia. 15: S167-9. PMID 26297272 DOI: 10.1016/j.clml.2015.02.010  0.213
2021 Shukla NM, Chan M, Lao FS, Chu PJ, Belsuzarri M, Yao S, Nan J, Sato-Kaneko F, Saito T, Hayashi T, Corr M, Carson DA, Cottam HB. Structure-activity relationship studies in substituted sulfamoyl benzamidothiazoles that prolong NF-κB activation. Bioorganic & Medicinal Chemistry. 43: 116242. PMID 34274759 DOI: 10.1016/j.bmc.2021.116242  0.212
1999 Chukwuocha RU, Zhang B, Lai CJ, Scavulli JF, Albani S, Carson DA, Chen PP. Isolation of an IgG monoclonal anti-dnaJ antibody from an immunoglobulin combinatorial library from a patient with rheumatoid arthritis. The Journal of Rheumatology. 26: 1439-45. PMID 10405927  0.211
2013 Chan M, Hayashi T, Mathewson RD, Nour A, Hayashi Y, Yao S, Tawatao RI, Crain B, Tsigelny IF, Kouznetsova VL, Messer K, Pu M, Corr M, Carson DA, Cottam HB. Identification of substituted pyrimido[5,4-b]indoles as selective Toll-like receptor 4 ligands. Journal of Medicinal Chemistry. 56: 4206-23. PMID 23656327 DOI: 10.1021/jm301694x  0.21
2008 GUERNE P, VAUGHAN JH, CARSON DA, TERKELTAUB B, LOTZ M. Interleukin-6 (IL-6) and Joint Tissues Annals of the New York Academy of Sciences. 557: 558-561. DOI: 10.1111/J.1749-6632.1989.Tb24065.X  0.21
2014 Hayashi T, Crain B, Yao S, Caneda CD, Cottam HB, Chan M, Corr M, Carson DA. Novel synthetic toll-like receptor 4/MD2 ligands attenuate sterile inflammation. The Journal of Pharmacology and Experimental Therapeutics. 350: 330-40. PMID 24893985 DOI: 10.1124/jpet.114.214312  0.207
2003 Carson DA, Leoni LM. Hairy-cell leukaemia as a model for drug development. Best Practice & Research. Clinical Haematology. 16: 83-9. PMID 12670467 DOI: 10.1016/S1521-6926(02)00090-7  0.207
2012 Hayashi T, Yao S, Crain B, Chan M, Tawatao RI, Gray C, Vuong L, Lao F, Cottam HB, Carson DA, Corr M. Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system. Plos One. 7: e45860. PMID 23029281 DOI: 10.1371/journal.pone.0045860  0.207
2008 Hayashi T, Cottam HB, Chan M, Jin G, Tawatao RI, Crain B, Ronacher L, Messer K, Carson DA, Corr M. Mast cell-dependent anorexia and hypothermia induced by mucosal activation of Toll-like receptor 7. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R123-32. PMID 18480244 DOI: 10.1152/ajpregu.00527.2007  0.206
2014 Nour A, Hayashi T, Chan M, Yao S, Tawatao RI, Crain B, Tsigelny IF, Kouznetsova VL, Ahmadiiveli A, Messer K, Pu M, Corr M, Carson DA, Cottam HB. Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands. Bioorganic & Medicinal Chemistry Letters. 24: 4931-8. PMID 25288184 DOI: 10.1016/j.bmcl.2014.09.039  0.205
2002 Rhee CS, Sen M, Lu D, Wu C, Leoni L, Rubin J, Corr M, Carson DA. Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas. Oncogene. 21: 6598-605. PMID 12242657 DOI: 10.1038/sj.onc.1205920  0.205
1992 Tzioufas AG, Boumba DS, Skopouli FN, Carson DA, Moutsopoulos HM. Inheritance of monoclonal rheumatoid factor cross-reactive idiotypes in primary Sjögren's syndrome (pSS). Comparative studies of a rabbit polyclonal anti-idiotype and 17109 monoclonal anti-idiotype. European Journal of Clinical Investigation. 22: 475-81. PMID 1516595 DOI: 10.1111/j.1365-2362.1992.tb01493.x  0.203
2020 Hosoya T, Shukla NM, Fujita Y, Yao S, Lao FS, Baba H, Yasuda S, Cottam HB, Carson DA, Hayashi T, Corr M. Identification of Compounds With Glucocorticoid Sparing Effects on Suppression of Chemokine and Cytokine Production by Rheumatoid Arthritis Fibroblast-Like Synoviocytes. Frontiers in Pharmacology. 11: 607713. PMID 33390996 DOI: 10.3389/fphar.2020.607713  0.202
1987 Carson DA, Chen PP, Kipps TJ, Radoux V, Jirik F, Goldfien RD, Fox RI, Silverman GJ, Fong S. Molecular basis for the cross-reactive idiotypes on human anti-IgG autoantibodies (rheumatoid factors) Ciba Foundation Symposium. 129: 123-134. PMID 3315499 DOI: 10.1002/9780470513484.ch9  0.202
1982 Carson D. Progress in Clinical Immunology. Volume 4. Edited by Robert S. Schwartz, MD, New York, Grune and Stratton, Inc., 1980. 179 pages. Illustrated. $23.50 Arthritis & Rheumatism. 25: 360-360. DOI: 10.1002/Art.1780250323  0.199
1993 Watanabe A, Raz E, Kohsaka H, Tighe H, Baird SM, Kipps TJ, Carson DA. Induction of Antibodies to a κ V Region by Gene Immunization Journal of Immunology. 151: 2871-2876. PMID 8360497  0.198
2018 Shukla NM, Arimoto KI, Yao S, Fan JB, Zhang Y, Sato-Kaneko F, Lao FS, Hosoya T, Messer K, Pu M, Cottam HB, Carson DA, Hayashi T, Zhang DE, Corr M. Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants. Slas Discovery : Advancing Life Sciences R & D. 2472555218774308. PMID 29751735 DOI: 10.1177/2472555218774308  0.198
1993 Saven A, Kawasaki H, Carrera CJ, Waltz T, Copeland B, Zyroff J, Kosty M, Carson DA, Beutler E, Piro LD. 2-Chlorodeoxyadenosine dose escalation in nonhematologic malignancies Journal of Clinical Oncology. 11: 671-678. PMID 8097527 DOI: 10.1200/Jco.1993.11.4.671  0.197
2011 Lu D, Choi MY, Yu J, Castro JE, Kipps TJ, Carson DA. Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 13253-7. PMID 21788521 DOI: 10.1073/pnas.1110431108  0.197
1996 Cottam HB, Shih H, Tehrani LR, Wasson DB, Carson DA. Substituted xanthines, pteridinediones, and related compounds as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor α Journal of Medicinal Chemistry. 39: 2-9. PMID 8568809 DOI: 10.1021/jm940845j  0.195
2021 Saito T, Sako Y, Sato-Kaneko F, Hosoya T, Yao S, Lao FS, Shpigelman J, Messer K, Pu M, Shukla NM, Chan M, Chu PJ, Cottam HB, Hayashi T, Carson DA, et al. Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge. Frontiers in Immunology. 12: 701445. PMID 34650551 DOI: 10.3389/fimmu.2021.701445  0.195
2017 Chan M, Kakitsubata Y, Hayashi T, Ahmadi A, Yao S, Shukla NM, Oyama SY, Baba A, Nguyen B, Corr M, Suda Y, Carson DA, Cottam HB, Wakao M. Structure-activity relationship studies of pyrimido[5,4-b]indoles as selective Toll-like receptor 4 ligands. Journal of Medicinal Chemistry. PMID 29049886 DOI: 10.1021/acs.jmedchem.7b00797  0.194
1988 Carson DA, Haertle T, Bruce Wasson D, Richman DD. Biochemical genetic analysis of 2′,3′-dideoxyadenosine metabolism in human T lymphocytes Biochemical and Biophysical Research Communications. 151: 788-793. PMID 3258154 DOI: 10.1016/S0006-291X(88)80350-4  0.194
1986 Chen PP, Albrandt K, Orida NK, Radoux V, Chen EY, Schrantz R, Liu FT, Carson DA. Genetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies. Proceedings of the National Academy of Sciences of the United States of America. 83: 8318-22. PMID 3095834 DOI: 10.1073/Pnas.83.21.8318  0.193
1979 Catalano MA, Carson DA, Slovin SF, Richman DD, Vaughan JH. Antibodies to Epstein-Barr virus-determined antigens in normal subjects and in patients with seropositive rheumatoid arthritis Proceedings of the National Academy of Sciences of the United States of America. 76: 5825-5828. PMID 230491 DOI: 10.1073/Pnas.76.11.5825  0.19
1997 Warnatz K, Brinson D, Carson DA, Tighe H. Prior to elimination by IgG RF B cells are effective enhancers of secondary immune responses Immunobiology. 197: 254.  0.187
2019 Chan M, Lao FS, Chu PJ, Shpigelman J, Yao S, Nan J, Sato-Kaneko F, Li V, Hayashi T, Corr M, Carson DA, Cottam HB, Shukla NM. Structure-Activity Relationship Studies to Identify Affinity Probes in Bis-aryl Sulfonamides that Prolong Immune Stimuli. Journal of Medicinal Chemistry. PMID 31603681 DOI: 10.1021/acs.jmedchem.9b00870  0.187
1978 Robbins DL, Moore TL, Carson DA, Vaughan JH. Relative reactivities of rheumatoid factors in serum and cells. Evidence for a selective deficiency in serum rheumatoid factor. Arthritis and Rheumatism. 21: 820-6. PMID 358993 DOI: 10.1002/art.1780210713  0.186
2011 Norton JT, Hayashi T, Crain B, Corr M, Carson DA. Role of IL-1 receptor-associated kinase-M (IRAK-M) in priming of immune and inflammatory responses by nitrogen bisphosphonates. Proceedings of the National Academy of Sciences of the United States of America. 108: 11163-8. PMID 21690387 DOI: 10.1073/pnas.1107899108  0.184
2004 Diccianni MB, Yu J, Meppelink G, de Vries M, Shao L, Gebauer S, Shih H, Roberts W, Kilcoin NP, Pullen J, Carson DA, Yu AL. 3-amino thioacridone inhibits DNA synthesis and induce DNA damage in T-cell acute lymphoblastic leukemia (T-ALL) in a p16-dependent manner. Journal of Experimental Therapeutics & Oncology. 4: 223-37. PMID 15724842  0.184
2008 Wrasidlo W, Mielgo A, Torres VA, Barbero S, Stoletov K, Suyama TL, Klemke RL, Gerwick WH, Carson DA, Stupack DG. The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proceedings of the National Academy of Sciences of the United States of America. 105: 2313-8. PMID 18268346 DOI: 10.1073/Pnas.0712198105  0.184
1996 Hori H, Tran P, Carrera CJ, Hori Y, Rosenbach MD, Carson DA, Nobori T. Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells Cancer Research. 56: 5653-5658. PMID 8971171  0.184
2016 Ager C, Reilley M, Nicholas C, Bartkowiak T, Jaiswal A, Curran M, Albershardt TC, Bajaj A, Archer JF, Reeves RS, Ngo LY, Berglund P, ter Meulen J, Denis C, Ghadially H, ... ... Carson DA, et al. 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two Journal For Immunotherapy of Cancer. 4. DOI: 10.1186/S40425-016-0173-6  0.183
2004 Lu D, Zhao Y, Tawatao R, Cottam HB, Sen M, Leoni LM, Kipps TJ, Corr M, Carson DA. Activation of the Wnt signaling pathway in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 101: 3118-23. PMID 14973184 DOI: 10.1073/pnas.0308648100  0.182
2022 Shukla NM, Sato-Kaneko F, Yao S, Pu M, Chan M, Lao FS, Sako Y, Saito T, Messer K, Hayashi T, Cottam HB, Corr M, Carson DA. A Triple High Throughput Screening for Extracellular Vesicle Inducing Agents With Immunostimulatory Activity. Frontiers in Pharmacology. 13: 869649. PMID 35479316 DOI: 10.3389/fphar.2022.869649  0.181
2012 Ma W, Gutierrez A, Goff DJ, Geron I, Sadarangani A, Jamieson CA, Court AC, Shih AY, Jiang Q, Wu CC, Li K, Smith KM, Crews LA, Gibson NW, Deichaite I, ... ... Carson DA, et al. NOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive niches. Plos One. 7: e39725. PMID 22768113 DOI: 10.1371/Journal.Pone.0039725  0.18
2006 Jin G, Wu CC, Tawatao RI, Chan M, Carson DA, Cottam HB. Synthesis and immunostimulatory activity of 8-substituted amino 9-benzyladenines as potent Toll-like receptor 7 agonists. Bioorganic & Medicinal Chemistry Letters. 16: 4559-63. PMID 16784848 DOI: 10.1016/j.bmcl.2006.06.017  0.179
2020 Chen T, Liu K, Xu J, Zhan T, Liu M, Li L, Yang Z, Yuan S, Zou W, Lin G, Carson DA, Wu CCN, Wang X. Synthetic and immunological studies on the OCT4 immunodominant motif antigen-based anti-cancer vaccine. Cancer Biology & Medicine. 17: 132-141. PMID 32296581 DOI: 10.20892/j.issn.2095-3941.2019.0224  0.178
2007 Wu CC, Hayashi T, Takabayashi K, Sabet M, Smee DF, Guiney DD, Cottam HB, Carson DA. Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand. Proceedings of the National Academy of Sciences of the United States of America. 104: 3990-5. PMID 17360465 DOI: 10.1073/pnas.0611624104  0.178
2021 Shpigelman J, Lao FS, Yao S, Li C, Saito T, Sato-Kaneko F, Nolan JP, Shukla NM, Pu M, Messer K, Cottam HB, Carson DA, Corr M, Hayashi T. Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release. Frontiers in Pharmacology. 12: 668609. PMID 33935791 DOI: 10.3389/fphar.2021.668609  0.177
2012 Hayashi T, Yao S, Crain B, Chan M, Cottam HB, Lao F, Carson DA, Corr M. Mast cell-mediated inhibition of abdominal neutrophil inflammation by a PEGylated TLR7 ligand. Mediators of Inflammation. 2012: 262394. PMID 22619481 DOI: 10.1155/2012/262394  0.175
2020 Gumber D, Do M, Suresh Kumar N, Sonavane PR, Wu CCN, Cruz LS, Grainger S, Carson D, Gaasterland T, Willert K. Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells. Elife. 9. PMID 33331818 DOI: 10.7554/eLife.63060  0.175
1994 Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers Nature. 368: 753-756. PMID 8152487 DOI: 10.1038/368753a0  0.175
2006 Carson DA, Zvaifler NJ. Jarvis Edwin Seegmiller, MD, 1920-2006 Arthritis & Rheumatism. 54: 3067-3067. DOI: 10.1002/Art.22185  0.174
1997 Corr M, Tighe H, Lee D, Dudler J, Trieu M, Brinson DC, Carson DA. Costimulation Provided by DNA Immunization Enhances Antitumor Immunity Journal of Immunology. 159: 4999-5004. PMID 9366427  0.174
1992 Hostetler KY, Richman DD, Carson DA, Stuhmiller LM, Van Wijk GMT, Van den Bosch H. Greatly enhanced inhibition of human immunodeficiency virus type 1 replication in CEM and HT4-6C cells by 3'-deoxythymidine diphosphate dimyristoylglycerol, a lipid prodrug of 3'-deoxythymidine Antimicrobial Agents and Chemotherapy. 36: 2025-2029. PMID 1416896 DOI: 10.1128/Aac.36.9.2025  0.171
2020 Sato-Kaneko F, Yao S, Lao FS, Shpigelman J, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Chu PJ, Burkhart D, Schoener R, Matsutani T, Carson DA, Corr M, et al. A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity. Frontiers in Immunology. 11: 1207. PMID 32636840 DOI: 10.3389/fimmu.2020.01207  0.171
2021 Do M, Wu CCN, Sonavane PR, Juarez EF, Adams SR, Ross J, Rodriguez Y Baena A, Patel C, Mesirov JP, Carson DA, Advani SJ, Willert K. A FZD7-specific antibody-drug conjugate induces ovarian tumor regression in preclinical models. Molecular Cancer Therapeutics. PMID 34667113 DOI: 10.1158/1535-7163.MCT-21-0548  0.17
1985 Goldfien RD, Chen PP, Fong S, Carson DA. Synthetic peptides corresponding to third hypervariable region of human monoclonal IgM rheumatoid factor heavy chains define an immunodominant idiotype. The Journal of Experimental Medicine. 162: 756-61. PMID 3926939 DOI: 10.1084/jem.162.2.756  0.169
2003 Wu CC, Castro JE, Motta M, Cottam HB, Kyburz D, Kipps TJ, Corr M, Carson DA. Selection of oligonucleotide aptamers with enhanced uptake and activation of human leukemia B cells. Human Gene Therapy. 14: 849-60. PMID 12828856 DOI: 10.1089/104303403765701141  0.169
1996 RAZ E, TIGHE H, SATO Y, ROMAN M, SWAIN S, CARSON D, SPIEGELBERG H. 717 Inhibition of specific IgE antibody formation by naked plasmid DNA immunization Journal of Allergy and Clinical Immunology. 97: 362-362. DOI: 10.1016/S0091-6749(96)80935-3  0.167
2014 Saenz R, Futalan D, Leutenez L, Eekhout F, Fecteau JF, Sundelius S, Sundqvist S, Larsson M, Hayashi T, Minev B, Carson D, Esener S, Messmer B, Messmer D. TLR4-dependent activation of dendritic cells by an HMGB1-derived peptide adjuvant. Journal of Translational Medicine. 12: 211. PMID 25123824 DOI: 10.1186/1479-5876-12-211  0.167
1980 Catalano MA, Carson DA, Stastny P, Freer S, Vaughan JH. Correlation between anti-RANA and anti-EBNA titers in normal subjects with and without HLA-DRw4. Arthritis and Rheumatism. 23: 1049-52. PMID 6251856 DOI: 10.1002/art.1780230913  0.166
1993 Ribeiro JM, Carson DA. Ca2+/Mg2+-dependent endonuclease from human spleen: Purification, properties, and role in apoptosis Biochemistry. 32: 9129-9136. PMID 8396424  0.166
2001 Prakken BJ, Carson DA, Albani S. T cell repertoire formation and molecular mimicry in rheumatoid arthritis. Current Directions in Autoimmunity. 3: 51-63. PMID 11791471  0.166
2007 Livengood AJ, Wu CC, Carson DA. Opposing roles of RNA receptors TLR3 and RIG-I in the inflammatory response to double-stranded RNA in a Kaposi's sarcoma cell line. Cellular Immunology. 249: 55-62. PMID 18155685 DOI: 10.1016/j.cellimm.2007.11.004  0.165
2017 Sato-Kaneko F, Yao S, Ahmadi A, Zhang SS, Hosoya T, Kaneda MM, Varner JA, Pu M, Messer KS, Guiducci C, Coffman RL, Kitaura K, Matsutani T, Suzuki R, Carson DA, et al. Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer. Jci Insight. 2. PMID 28931759 DOI: 10.1172/Jci.Insight.93397  0.165
2021 Sato-Kaneko F, Yao S, Lao FS, Nan J, Shpigelman J, Cheng A, Saito T, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Molina AJ, Corr M, Hayashi T, ... Carson DA, et al. Mitochondria-dependent synthetic small-molecule vaccine adjuvants for influenza virus infection. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34078669 DOI: 10.1073/pnas.2025718118  0.165
1984 Billings PB, Hoch SO, Carson DA, Vaughan JH. Comment on Venables letter Arthritis & Rheumatism. 27: 477-478. DOI: 10.1002/Art.1780270420  0.162
2018 Hosoya T, Sato-Kaneko F, Ahmadi A, Yao S, Lao F, Kitaura K, Matsutani T, Carson DA, Hayashi T. Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist. Proceedings of the National Academy of Sciences of the United States of America. PMID 29967183 DOI: 10.1073/pnas.1803281115  0.162
1992 Saven A, Carrera C, Carson D, Beutler E, Piro L. 2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T- cell lymphoma Blood. 80: 587-592. DOI: 10.1182/blood.V80.3.587.bloodjournal803587  0.161
2002 Ronaghy A, Prakken BJ, Takabayashi K, Firestein GS, Boyle D, Zvailfler NJ, Roord ST, Albani S, Carson DA, Raz E. Immunostimulatory DNA sequences influence the course of adjuvant arthritis. Journal of Immunology (Baltimore, Md. : 1950). 168: 51-6. PMID 11751945  0.16
1993 Yang PM, Olee T, Carson DA, Chen PP. Characterization of two highly homologous autoantibody-related VH1 genes in humans Scandinavian Journal of Immunology. 37: 504-508. PMID 8469934  0.16
1996 Hori H, Takabayashi K, Orvis L, Carson DA, Nobori T. Gene cloning and characterization of Pseudomonas putida L-methionine-α-deamino-γ-mercaptomethane-lyase Cancer Research. 56: 2116-2122. PMID 8616859  0.16
2020 Huang CH, Mendez N, Echeagaray OH, Weeks J, Wang J, Yao S, Blair SL, Gude N, Trogler WC, Carson DA, Hayashi T, Kummel AC. Immunostimulatory TLR7 agonist-nanoparticles together with checkpoint blockade for effective cancer immunotherapy. Advanced Therapeutics. 3. PMID 33644299 DOI: 10.1002/adtp.201900200  0.159
2015 Hayashi T, Yao S, Crain B, Promessi VJ, Shyu L, Sheng C, Kang M, Cottam HB, Carson DA, Corr M. Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes. Plos One. 10: e0129867. PMID 26076454 DOI: 10.1371/journal.pone.0129867  0.159
2001 Hua XH, Genini D, Gussio R, Tawatao R, Shih H, Kipps TJ, Carson DA, Leoni LM. Biochemical genetic analysis of indanocine resistance in human leukemia. Cancer Research. 61: 7248-54. PMID 11585762  0.158
2017 Goff PH, Hayashi T, He W, Yao S, Cottam HB, Tan GS, Crain B, Krammer F, Messer K, Pu M, Carson DA, Palese P, Corr M. Synthetic TLR4 and TLR7 ligands work additively via MyD88 to induce protective antiviral immunity in mice. Journal of Virology. PMID 28724768 DOI: 10.1128/Jvi.01050-17  0.158
2009 Chan M, Hayashi T, Kuy CS, Gray CS, Wu CC, Corr M, Wrasidlo W, Cottam HB, Carson DA. Synthesis and immunological characterization of toll-like receptor 7 agonistic conjugates. Bioconjugate Chemistry. 20: 1194-200. PMID 19445505 DOI: 10.1021/bc900054q  0.158
2019 Huang CH, Mendez N, Echeagaray OH, Weeks J, Wang J, Vallez CN, Gude N, Trogler WC, Carson DA, Hayashi T, Kummel AC. Conjugation of a Small Molecule TLR7 Agonist to Silica Nanoshells Enhances Adjuvant Activity. Acs Applied Materials & Interfaces. PMID 31276378 DOI: 10.1021/Acsami.9B08295  0.157
1994 Broor S, Kusari AB, Zhang B, Seth P, Richman DD, Carson DA, Wachsman W, Lotz M. Stimulation of HIV replication in mononuclear phagocytes by leukemia inhibitory factor Journal of Acquired Immune Deficiency Syndromes. 7: 647-654. PMID 8207643  0.157
1980 Carson DA, Kaye J. Deoxyribonucleoside toxicity in adenosine deaminase and purine nucleoside phosphorylase deficiency: implications for the development of new immunosuppressive agents. Ciba Foundation Symposium. 115-33. PMID 115660 DOI: 10.1002/9780470720516.ch8  0.157
2014 Zhang S, Cui B, Lai H, Liu G, Ghia EM, Widhopf GF, Zhang Z, Wu CC, Chen L, Wu R, Schwab R, Carson DA, Kipps TJ. Ovarian cancer stem cells express ROR1, which can be targeted for anti-cancer-stem-cell therapy. Proceedings of the National Academy of Sciences of the United States of America. 111: 17266-71. PMID 25411317 DOI: 10.1073/pnas.1419599111  0.155
1993 Nobori T, Szinai I, Amox D, Parker B, Olopade OI, Buchhagen DL, Carson DA. Methylthioadenosine phosphorylase deficiency in human non-small cell lung cancers Cancer Research. 53: 1098-1101. PMID 8382555  0.154
2006 Jin G, Wu CC, Carson DA, Cottam HB. Guanosine analog in the pyrido[2,3-d]pyrimidine ring system as a potential toll-like receptor agonist. Nucleosides, Nucleotides & Nucleic Acids. 25: 1391-7. PMID 17067960 DOI: 10.1080/15257770600918912  0.153
2009 Hayashi T, Gray CS, Chan M, Tawatao RI, Ronacher L, McGargill MA, Datta SK, Carson DA, Corr M. Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7. Proceedings of the National Academy of Sciences of the United States of America. 106: 2764-9. PMID 19188597 DOI: 10.1073/Pnas.0813037106  0.153
2023 Sako Y, Sato-Kaneko F, Shukla NM, Yao S, Belsuzarri MM, Chan M, Saito T, Lao FS, Kong H, Puffer M, Messer K, Pu M, Cottam HB, Carson DA, Hayashi T. Identification of a Novel Small Molecule That Enhances the Release of Extracellular Vesicles with Immunostimulatory Potency via Induction of Calcium Influx. Acs Chemical Biology. PMID 37039433 DOI: 10.1021/acschembio.3c00134  0.153
2011 Chan M, Hayashi T, Mathewson RD, Yao S, Gray C, Tawatao RI, Kalenian K, Zhang Y, Hayashi Y, Lao FS, Cottam HB, Carson DA. Synthesis and characterization of PEGylated toll like receptor 7 ligands. Bioconjugate Chemistry. 22: 445-54. PMID 21338093 DOI: 10.1021/bc1004813  0.152
2004 Wu CC, Lee J, Raz E, Corr M, Carson DA. Necessity of oligonucleotide aggregation for toll-like receptor 9 activation. The Journal of Biological Chemistry. 279: 33071-8. PMID 15184382 DOI: 10.1074/jbc.M311662200  0.152
1991 Beutler E, Piro LD, Saven A, Kay AC, Mcmillan R, Longmire R, Carrera CJ, Morin P, Carson DA. 2-chlorodeoxyadenosine (2-cda): A potent chemotherapeutic and immunosuppressive nucleoside Leukemia and Lymphoma. 5: 1-8. DOI: 10.3109/10428199109068099  0.152
2011 Nicolaou KC, Ellery SP, Rivas F, Saye K, Rogers E, Workinger TJ, Schallenberger M, Tawatao R, Montero A, Hessell A, Romesberg F, Carson D, Burton D. Synthesis and biological evaluation of 2',4'- and 3',4'-bridged nucleoside analogues. Bioorganic & Medicinal Chemistry. 19: 5648-69. PMID 21840722 DOI: 10.1016/J.Bmc.2011.07.022  0.151
2006 Barnard DL, Day CW, Bailey K, Heiner M, Montgomery R, Lauridsen L, Winslow S, Hoopes J, Li JK, Lee J, Carson DA, Cottam HB, Sidwell RW. Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin. Antiviral Research. 71: 53-63. PMID 16621037 DOI: 10.1016/J.Antiviral.2006.03.001  0.15
2019 Shankara Narayanan JS, Ray P, Hayashi T, Whisenant TC, Vicente D, Carson DA, Miller AM, Schoenberger SP, White RR. Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Anti-Tumor Immunity in a Murine Pancreatic Cancer Model. Cancer Immunology Research. PMID 31409607 DOI: 10.1158/2326-6066.Cir-19-0101  0.149
2014 Wu CC, Crain B, Yao S, Sabet M, Lao FS, Tawatao RI, Chan M, Smee DF, Julander JG, Cottam HB, Guiney DG, Corr M, Carson DA, Hayashi T. Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand. Journal of Innate Immunity. 6: 315-24. PMID 24192551 DOI: 10.1159/000355217  0.148
1988 Piro L, Carrera C, Beutler E, Carson D. 2-Chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukemia Blood. 72: 1069-1073. DOI: 10.1182/blood.V72.3.1069.bloodjournal7231069  0.148
2012 Norton JT, Hayashi T, Crain B, Cho JS, Miller LS, Corr M, Carson DA. Cutting edge: nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1. Journal of Immunology (Baltimore, Md. : 1950). 188: 2977-80. PMID 22387558 DOI: 10.4049/Jimmunol.1100830  0.147
2016 Bram Z, Louiset E, Ragazzon B, Renouf S, Wils J, Duparc C, Boutelet I, Rizk-Rabin M, Libé R, Young J, Carson D, Vantyghem MC, Szarek E, Martinez A, Stratakis CA, et al. PKA regulatory subunit 1A inactivating mutation induces serotonin signaling in primary pigmented nodular adrenal disease. Jci Insight. 1: e87958. PMID 27699247 DOI: 10.1172/jci.insight.87958  0.147
2021 Shinchi H, Yuki M, Yamauchi T, Niimura M, Wakao M, Cottam HB, Hayashi T, Carson DA, Moroishi T, Suda Y. Glyco-Nanoadjuvants: Sugar Structures on Carriers of a Small Molecule TLR7 Ligand Affect Their Immunostimulatory Activities. Acs Applied Bio Materials. 4: 2732-2741. PMID 35014312 DOI: 10.1021/acsabm.0c01639  0.143
2023 Shankara Narayanan JS, Hayashi T, Erdem S, McArdle S, Tiriac H, Ray P, Pu M, Mikulski Z, Miller A, Messer K, Carson D, Schoenberger S, White RR. Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model. Journal For Immunotherapy of Cancer. 11. PMID 36634919 DOI: 10.1136/jitc-2022-006133  0.143
2004 Hayashi T, Beck L, Rossetto C, Gong X, Takikawa O, Takabayashi K, Broide DH, Carson DA, Raz E. Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. The Journal of Clinical Investigation. 114: 270-9. PMID 15254594 DOI: 10.1172/Jci21275  0.141
1993 Carson DA, Ribeiro JM. Apoptosis and disease The Lancet. 341: 1251-1254. PMID 8098400 DOI: 10.1016/0140-6736(93)91154-E  0.14
1995 Carson DA, Lois A. Cancer progression and p53 The Lancet. 346: 1009-1011. PMID 7475551 DOI: 10.1016/S0140-6736(95)91693-8  0.14
1997 Cho CS, Wang X, Zhao Y, Carson DA, Chen PP. Genotyping by PCR-ELISA of a complex polymorphic region that contains one to four copies of six highly homologous human VH3 genes Proceedings of the Association of American Physicians. 109: 558-564. PMID 9394417  0.139
1987 Silverman GJ, Carson DA, Solomon A, Fong S. Human kappa light chain subgroup analysis with synthetic peptide-induced antisera. Journal of Immunological Methods. 95: 249-57. PMID 3098855 DOI: 10.1016/0022-1759(86)90412-6  0.138
1981 Carson DA, Chang KP. Phosphorylation and anti-leishmanial activity of formycin B. Biochemical and Biophysical Research Communications. 100: 1377-83. PMID 7271805 DOI: 10.1016/0006-291X(81)91976-8  0.137
2012 Kim Y, Gast SM, Endo T, Lu D, Carson D, Schmidt-Wolf IG. In vivo efficacy of the diuretic agent ethacrynic acid against multiple myeloma. Leukemia Research. 36: 598-600. PMID 22386728 DOI: 10.1016/j.leukres.2012.01.025  0.137
1984 Carson DA, Wasson DB, Yu A. Cell cycle independent lymphocytotoxicity of 2-chlorodeoxyadenosine. Advances in Experimental Medicine and Biology. 351-6. PMID 6144251 DOI: 10.1007/978-1-4757-0390-0_66  0.137
2002 Sen M, Carson DA. Wnt signaling in rheumatoid synoviocyte activation. Modern Rheumatology / the Japan Rheumatism Association. 12: 5-9. PMID 24383825 DOI: 10.3109/s101650200001  0.136
2004 Loughlin J, Dowling B, Chapman K, Marcelline L, Mustafa Z, Southam L, Ferreira A, Ciesielski C, Carson DA, Corr M. Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females. Proceedings of the National Academy of Sciences of the United States of America. 101: 9757-62. PMID 15210948 DOI: 10.1073/pnas.0403456101  0.135
1986 Carson DA, Seto S, Wasson DB, Carrera CJ. DNA strand breaks, NAD metabolism, and programmed cell death Experimental Cell Research. 164: 273-281. PMID 2940104 DOI: 10.1016/0014-4827(86)90028-5  0.135
1994 Zhang SY, Klein-Szanto AJ, Sauter ER, Shafarenko M, Mitsunaga S, Nobori T, Carson DA, Ridge JA, Goodrow TL. Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck. Cancer Research. 54: 5050-3. PMID 7923115  0.133
2008 Wu CC, Sabet M, Hayashi T, Tawatao R, Fierer J, Carson DA, Guiney DG, Corr M. In vivo efficacy of a phosphodiester TLR-9 aptamer and its beneficial effect in a pulmonary anthrax infection model. Cellular Immunology. 251: 78-85. PMID 18495099 DOI: 10.1016/j.cellimm.2008.04.001  0.132
2022 Sato-Kaneko F, Yao S, Lao FS, Sako Y, Jin J, Shukla NM, Cottam HB, Chan M, Belsuzarri MM, Carson DA, Hayashi T. A Dual Adjuvant System for Intranasal Boosting of Local and Systemic Immunity for Influenza Vaccination. Vaccines. 10. PMID 36298559 DOI: 10.3390/vaccines10101694  0.131
2014 Fernandez A, Huggins IJ, Perna L, Brafman D, Lu D, Yao S, Gaasterland T, Carson DA, Willert K. The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 1409-14. PMID 24474766 DOI: 10.1073/Pnas.1323697111  0.131
2017 Lenis A, Chamie K, Yao S, Carson D, Hayashi T. MP98-05 CHECKPOINT INHIBITION WITH SYSTEMIC ANTI-PROGRAMMED CELL DEATH LIGAND-1 AND INTRAVESICAL TMX-101 DECREASE TUMOR BURDEN IN A MOUSE MODEL OF UROTHELIAL CARCINOMA Journal of Urology. 197. DOI: 10.1016/j.juro.2017.02.3070  0.129
2019 Baba A, Wakao M, Shinchi H, Chan M, Hayashi T, Yao S, Cottam HB, Carson DA, Suda Y. Synthesis and immunostimulatory activity of sugar-conjugated TLR7 ligands. Bioorganic & Medicinal Chemistry Letters. 126840. PMID 31864800 DOI: 10.1016/j.bmcl.2019.126840  0.129
2010 Bashir A, Lu Q, Carson D, Raphael BJ, Liu YT, Bafna V. Optimizing PCR assays for DNA-based cancer diagnostics. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 17: 369-81. PMID 20377451 DOI: 10.1089/Cmb.2009.0203  0.128
2008 Schmidt M, Sievers E, Endo T, Lu D, Carson D, Schmidt-Wolf IG. Targeting Wnt pathway in lymphoma and myeloma cells. British Journal of Haematology. 144: 796-8. PMID 19036118 DOI: 10.1111/j.1365-2141.2008.07503.x  0.127
1998 Lee DJ, Corr M, Carson DA. Control of immune responses by gene immunization. Annals of Medicine. 30: 460-8. PMID 9814832  0.127
2015 Goff PH, Hayashi T, Martínez-Gil L, Corr M, Crain B, Yao S, Cottam HB, Chan M, Ramos I, Eggink D, Heshmati M, Krammer F, Messer K, Pu M, Fernandez-Sesma A, ... ... Carson DA, et al. Synthetic Toll-like receptor 4 (TLR4) and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained, and broadly protective responses. Journal of Virology. 89: 3221-35. PMID 25568203 DOI: 10.1128/Jvi.03337-14  0.126
2013 DeBoever C, Reid EG, Smith EN, Wang X, Dumaop W, Harismendy O, Carson D, Richman D, Masliah E, Frazer KA. Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomas. Plos One. 8: e73956. PMID 24023918 DOI: 10.1371/Journal.Pone.0073956  0.125
2011 Hayashi T, Chan M, Norton JT, Wu CC, Yao S, Cottam HB, Tawatao RI, Corr M, Carson DA, Daniels GA. Additive melanoma suppression with intralesional phospholipid-conjugated TLR7 agonists and systemic IL-2. Melanoma Research. 21: 66-75. PMID 21030882 DOI: 10.1097/CMR.0b013e328340ce6c  0.124
2022 Shinchi H, Komaki F, Yuki M, Ohara H, Hayakawa N, Wakao M, Cottam HB, Hayashi T, Carson DA, Moroishi T, Suda Y. Glyco-Nanoadjuvants: Impact of Linker Length for Conjugating a Synthetic Small-Molecule TLR7 Ligand to Glyco-Nanoparticles on Immunostimulatory Effects. Acs Chemical Biology. 17: 957-968. PMID 35353497 DOI: 10.1021/acschembio.2c00108  0.121
2019 Zhang S, Zhang H, Ghia EM, Huang J, Wu L, Zhang J, Lam S, Lei Y, He J, Cui B, Widhopf GF, Yu J, Schwab R, Messer K, Jiang W, ... ... Carson DA, et al. Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody. Proceedings of the National Academy of Sciences of the United States of America. PMID 30622177 DOI: 10.1073/pnas.1816262116  0.121
2015 Barrett CL, DeBoever C, Jepsen K, Saenz CC, Carson DA, Frazer KA. Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy. Proceedings of the National Academy of Sciences of the United States of America. 112: E3050-7. PMID 26015570 DOI: 10.1073/Pnas.1508057112  0.12
2021 Wang Q, Kim SY, Matsushita H, Wang Z, Pandyarajan V, Matsuda M, Ohashi K, Tsuchiya T, Roh YS, Kiani C, Zhao Y, Chan M, Devkota S, Lu SC, Hayashi T, ... Carson DA, et al. Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33443222 DOI: 10.1073/pnas.2020868118  0.12
2006 Lee J, Wu CC, Lee KJ, Chuang TH, Katakura K, Liu YT, Chan M, Tawatao R, Chung M, Shen C, Cottam HB, Lai MM, Raz E, Carson DA. Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proceedings of the National Academy of Sciences of the United States of America. 103: 1828-33. PMID 16446426 DOI: 10.1073/Pnas.0510801103  0.12
2010 Zhang Y, Elliot G, Saldanha A, Tsigelny I, Carson D, Wrasidlo W. Synthesis of 5-(6-hydroxy-7H-purine-8-ylthio)- 2-(N-hydroxyformamido)pentanoic acid. Beilstein Journal of Organic Chemistry. 6: 742-7. PMID 20978615 DOI: 10.3762/bjoc.6.93  0.119
2005 Kolluri SK, Corr M, James SY, Bernasconi M, Lu D, Liu W, Cottam HB, Leoni LM, Carson DA, Zhang XK. The R-enantiomer of the nonsteroidal antiinflammatory drug etodolac binds retinoid X receptor and induces tumor-selective apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 2525-30. PMID 15699354 DOI: 10.1073/pnas.0409721102  0.118
2000 Shih H, Deng L, Carrera CJ, Adachi S, Cottam HB, Carson DA. Rational design, synthesis and structure-activity relationships of antitumor (E)-2-benzylidene-1-tetralones and (E)-2-benzylidene-1-indanones. Bioorganic & Medicinal Chemistry Letters. 10: 487-90. PMID 10743954 DOI: 10.1016/S0960-894X(00)00032-9  0.117
2016 Moroishi T, Hayashi T, Pan WW, Fujita Y, Holt MV, Qin J, Carson DA, Guan KL. The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity. Cell. 167: 1525-1539.e17. PMID 27912060 DOI: 10.1016/J.Cell.2016.11.005  0.117
2008 Lu Q, Nunez E, Lin C, Christensen K, Downs T, Carson DA, Wang-Rodriguez J, Liu YT. A sensitive array-based assay for identifying multiple TMPRSS2:ERG fusion gene variants. Nucleic Acids Research. 36: e130. PMID 18794177 DOI: 10.1093/Nar/Gkn585  0.116
2013 Barrett CL, Schwab RB, Jung H, Crain B, Goff DJ, Jamieson CH, Thistlethwaite PA, Harismendy O, Carson DA, Frazer KA. Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancer. Plos One. 8: e58714. PMID 23527012 DOI: 10.1371/Journal.Pone.0058714  0.111
2015 Schwab RB, Kato S, Crain B, Pu M, Messer K, Weidner N, Blair SL, Wallace AM, Carson DA, Parker BA. A window-of-opportunity biomarker study of etodolac in resectable breast cancer. Cancer Medicine. PMID 26275572 DOI: 10.1002/cam4.512  0.111
2019 Battistella C, Callmann CE, Thompson MP, Yao S, Yeldandi AV, Hayashi T, Carson DA, Gianneschi NC. Delivery of Immunotherapeutic Nanoparticles to Tumors via Enzyme-Directed Assembly. Advanced Healthcare Materials. e1901105. PMID 31664791 DOI: 10.1002/Adhm.201901105  0.111
2020 Blumenthal A, Martin-Orozco E, McBride JW, Carson DA, Sen M. Editorial: Wnt Signaling in Immune Cell Regulation During Microbial Infection and Cancer. Frontiers in Immunology. 11: 1133. PMID 32582205 DOI: 10.3389/fimmu.2020.01133  0.11
2018 Shukla NM, Chan M, Hayashi T, Carson DA, Cottam HB. Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators. Acs Medicinal Chemistry Letters. 9: 1156-1159. PMID 30613317 DOI: 10.1021/acsmedchemlett.8b00566  0.109
2013 Crain B, Yao S, Keophilaone V, Promessi V, Kang M, Barberis A, Maj R, Mura E, Passini N, Holldack J, Ochoa R, Cottam HB, Carson DA, Hayashi T. Inhibition of keratinocyte proliferation by phospholipid-conjugates of a TLR7 ligand in a Myc-induced hyperplastic actinic keratosis model in the absence of systemic side effects. European Journal of Dermatology : Ejd. 23: 618-28. PMID 24225049 DOI: 10.1684/ejd.2013.2155  0.109
2015 Shinchi H, Crain B, Yao S, Chan M, Zhang SS, Ahmadiiveli A, Suda Y, Hayashi T, Cottam HB, Carson DA. Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides. Bioconjugate Chemistry. 26: 1713-23. PMID 26193334 DOI: 10.1021/acs.bioconjchem.5b00285  0.108
2007 Liu YT, Carson DA. A novel approach for determining cancer genomic breakpoints in the presence of normal DNA. Plos One. 2: e380. PMID 17440616 DOI: 10.1371/Journal.Pone.0000380  0.104
2004 Sen M, Cheng YH, Goldring MB, Lotz MK, Carson DA. WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes. Arthritis and Rheumatism. 50: 488-97. PMID 14872491 DOI: 10.1002/art.20005  0.104
2011 Kim Y, Alpmann P, Blaum-Feder S, Krämer S, Endo T, Lu D, Carson D, Schmidt-Wolf IG. Increased in vivo efficacy of lenalidomide by addition of piroctone olamine. In Vivo (Athens, Greece). 25: 99-103. PMID 21282741  0.102
2009 Lu D, Carson DA. Spiperone enhances intracellular calcium level and inhibits the Wnt signaling pathway. Bmc Pharmacology. 9: 13. PMID 19948059 DOI: 10.1186/1471-2210-9-13  0.102
2003 Kyburz D, Rethage J, Seibl R, Lauener R, Gay RE, Carson DA, Gay S. Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling. Arthritis and Rheumatism. 48: 642-50. PMID 12632416 DOI: 10.1002/art.10848  0.101
2002 Sen M, Reifert J, Lauterbach K, Wolf V, Rubin JS, Corr M, Carson DA. Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes. Arthritis and Rheumatism. 46: 2867-77. PMID 12428226 DOI: 10.1002/Art.10593  0.1
2013 Wu RP, Li H, Rassenti LZ, Hayashi T, Wu CN, Kipps TJ, Messer K, Carson DA. Increased aldehyde dehydrogenase activity in high-risk chronic lymphocytic leukemia. Leukemia & Lymphoma. 54: 400-2. PMID 22784365 DOI: 10.3109/10428194.2012.709630  0.098
2000 Hua XH, Leoni L, Shih H, Carrera CJ, Carson DA. Induction of apoptosis by microtubule disrupting drugs in chronic lymphocytic leukemia Blood. 96: 169a.  0.097
1985 Chen PP, Kabat EA, Wu TT, Fong S, Carson DA. Possible involvement of human D minigenes in the first complementarity-determining region of kappa light chains. Proceedings of the National Academy of Sciences of the United States of America. 82: 2125-7. PMID 3920660 DOI: 10.1073/pnas.82.7.2125  0.096
1981 Carson D. Divine Sovereignty and Human Responsibility in Philo Novum Testamentum. 23: 148-164. DOI: 10.1163/156853681X00223  0.095
2002 Shih H, Cottam HB, Carson DA. Facile synthesis of 9-substituted 9-deazapurines as potential purine nucleoside phosphorylase inhibitors. Chemical & Pharmaceutical Bulletin. 50: 364-7. PMID 11911199 DOI: 10.1248/cpb.50.364  0.094
2012 Millar S, Carson D. Clinical phenotypes of autoimmune polyendocrinopathycandidiasis-ectodermal dystrophy seen in the Northern Ireland paediatric population over the last 30 years. The Ulster Medical Journal. 81: 118-22. PMID 23620608  0.091
2011 Lu D, Carson DA. Inhibition of Wnt signaling and cancer stem cells. Oncotarget. 2: 587. PMID 21860066  0.09
2009 Yang D, Pornpattananangkul D, Nakatsuji T, Chan M, Carson D, Huang CM, Zhang L. The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes. Biomaterials. 30: 6035-40. PMID 19665786 DOI: 10.1016/J.Biomaterials.2009.07.033  0.087
2011 Schmidt M, Kim Y, Gast SM, Endo T, Lu D, Carson D, Schmidt-Wolf IG. Increased in vivo efficacy of lenalidomide and thalidomide by addition of ethacrynic acid. In Vivo (Athens, Greece). 25: 325-33. PMID 21576405  0.087
1990 Carson DA, Haertle T, Carrera CJ, Willis EH, Wasson DB, Richman DD. 2-halo-2',3'-dideoxyadenosines: metabolically stable dideoxynucleosides with activity against the human immunodeficiency virus (HIV). Advances in Experimental Medicine and Biology. 395-8. PMID 2610127 DOI: 10.1007/978-1-4684-5676-9_58  0.085
2010 Shi L, Carson D. Collagenase Santyl ointment: a selective agent for wound debridement. Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society. 36: S12-6. PMID 19918145 DOI: 10.1097/WON.0b013e3181bfdd1a  0.083
2017 Griffin JI, Cheng SKK, Hayashi T, Carson D, Saraswathy M, Nair DP, Simberg D. Cell-penetrating peptide CGKRK mediates efficient and widespread targeting of bladder mucosa following focal injury. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 28428051 DOI: 10.1016/J.Nano.2017.04.004  0.083
1982 Carson DA, Chang KP. Selective killing of Leishmania infected mouse macrophages by 6-methylpurine 2'-deoxyriboside. Life Sciences. 29: 1617-21. PMID 7311709 DOI: 10.1016/0024-3205(81)90062-X  0.083
2011 Kim Y, Reifenberger G, Lu D, Endo T, Carson DA, Gast SM, Meschenmoser K, Nowak M, Schmidt-Wolf IG. Influencing the Wnt signaling pathway in multiple myeloma. Anticancer Research. 31: 725-30. PMID 21378363  0.082
2010 LEVY SG, WASSON DB, CARSON DA, COTTAM HB. ChemInform Abstract: Synthesis of 2-Chloro-2′-5′-dideoxy-5′- difluoromethylphosphinyladenosine (XI): A Nonhydrolyzable Isosteric, Isopolar Analogue of 2-Chlorodeoxyadenosine Monophosphate. Cheminform. 27: no-no. DOI: 10.1002/chin.199648248  0.081
1995 Carson DA, Tan EM. Apoptosis in rheumatic disease Bulletin On the Rheumatic Diseases. 44: 1-3. PMID 7874249  0.078
2012 Kim Y, Schmidt M, Endo T, Lu D, Carson D, Schmidt-Wolf IG. Targeting the Wnt/beta-catenin pathway with the antifungal agent ciclopirox olamine in a murine myeloma model. In Vivo (Athens, Greece). 25: 887-93. PMID 22021681  0.078
2002 Sen M, Carson DA. Wnt signalling in rheumatoid synoviocyte activation Modern Rheumatology. 12: 5-9.  0.077
2012 Zinkernagel AS, Hruz P, Uchiyama S, von Köckritz-Blickwede M, Schuepbach RA, Hayashi T, Carson DA, Nizet V. Importance of Toll-like receptor 9 in host defense against M1T1 group A Streptococcus infections. Journal of Innate Immunity. 4: 213-8. PMID 21860217 DOI: 10.1159/000329550  0.076
2015 Shinchi H, Crain B, Yao S, Chan M, Zhang SS, Ahmadiiveli A, Suda Y, Hayashi T, Cottam HB, Carson DA. Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides Bioconjugate Chemistry. 26: 1713-1723. DOI: 10.1021/acs.bioconjchem.5b00285  0.069
2010 Hayashi T, Crain B, Corr M, Chan M, Cottam HB, Maj R, Barberis A, Leoni L, Carson DA. Intravesical Toll-like receptor 7 agonist R-837: optimization of its formulation in an orthotopic mouse model of bladder cancer. International Journal of Urology : Official Journal of the Japanese Urological Association. 17: 483-90. PMID 20337728 DOI: 10.1111/j.1442-2042.2010.02503.x  0.068
2015 DeBoever C, Ghia EM, Shepard PJ, Rassenti L, Barrett CL, Jepsen K, Jamieson CH, Carson D, Kipps TJ, Frazer KA. Transcriptome sequencing reveals potential mechanism of cryptic 3' splice site selection in SF3B1-mutated cancers. Plos Computational Biology. 11: e1004105. PMID 25768983 DOI: 10.1371/Journal.Pcbi.1004105  0.068
1987 MONTGOMERY JA, SHORTNACY AT, CARSON DA, SECRIST JAI. ChemInform Abstract: 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)guanine: A Metabolically Stable Cytotoxic Analogue of 2′-Deoxyguanosine. Cheminform. 18. DOI: 10.1002/chin.198715360  0.065
2007 Bashir A, Liu YT, Raphael BJ, Carson D, Bafna V. Optimization of primer design for the detection of variable genomic lesions in cancer. Bioinformatics (Oxford, England). 23: 2807-15. PMID 17766270 DOI: 10.1093/Bioinformatics/Btm390  0.063
1997 Perry A, Nobori T, Rul N, Anderl K, Borell T, Mohapatra G, Feuerstein B, Jenkins R, Carson D. Detection of p16 gene deletions in gliomas: Fish vs. quantitative PCR Cancer Genetics and Cytogenetics. 98: 163. DOI: 10.1016/S0165-4608(97)90295-8  0.06
2006 Cottam HB, Carson DA. 2-Chlorodeoxyadenosine (Cladribine): Rational Development of a Novel Chemotherapeutic Agent Drug Discovery Research: New Frontiers in the Post-Genomic Era. 393-407. DOI: 10.1002/9780470131862.ch16  0.058
2011 Shi L, Ermis R, Kiedaisch B, Carson D. The effect of various wound dressings on the activity of debriding enzymes. Advances in Skin & Wound Care. 23: 456-62. PMID 20859076 DOI: 10.1097/01.ASW.0000383224.64524.ae  0.057
1994 Carson DA. The value of epitope mapping in autoimmune diseases Journal of Clinical Investigation. 94: 1713. PMID 7962518  0.056
1996 Krawczynski K, Alter MJ, Tankersley DL, Beach M, Robertson BH, Lambert S, Kuo G, Spelbring JE, Meeks E, Sinha S, Carson DA. Effect of immune globulin on the prevention of experimental hepatitis C virus infection. The Journal of Infectious Diseases. 173: 822-8. PMID 8603959  0.054
2011 Shih H, Shih RJ, Carson DA. New heterocycles of 2,3-diaryl-substituted maleic hydrazides Journal of Heterocyclic Chemistry. 48: 1243-1250. DOI: 10.1002/jhet.631  0.051
2014 Baghdadchi S, Liu K, Knapp J, Prager G, Graves S, Akrami K, Manuel R, Bastos R, Reid E, Carson D, Esener S, Carson J, Liu YT. An innovative system for 3D clinical photography in the resource-limited settings Journal of Translational Medicine. 12. PMID 24929434 DOI: 10.1186/1479-5876-12-169  0.05
2012 Pu M, Hayashi T, Cottam H, Mulvaney J, Arkin M, Corr M, Carson D, Messer K. Analysis of high-throughput screening assays using cluster enrichment. Statistics in Medicine. 31: 4175-89. PMID 22763983 DOI: 10.1002/Sim.5455  0.05
2016 Matsushita H, Noh YS, Kiyani A, Zhang B, Liang S, Carson D, Hayashi T, Seki E. Sa1651 TLR7 Signaling As a Mechanism and Therapeutic Target for Mouse Model of Alcoholic Hepatitis Gastroenterology. 150: S1086. DOI: 10.1016/S0016-5085(16)33665-4  0.049
2011 Millar S, Bradley L, Donnelly DE, Carson D, Morrison PJ. Familial pediatric endocrine tumors. The Oncologist. 16: 1388-96. PMID 21934104 DOI: 10.1634/theoncologist.2011-0120  0.049
2015 Matsushita H, Roh YS, Kiyani A, Zhang B, Liang S, Carson D, Hayashi T, Seki E. 647 TLR7 Signaling As Potential Therapeutic Target for Mouse Model of Alcoholic Hepatitis Gastroenterology. 148: S-989. DOI: 10.1016/S0016-5085(15)33378-3  0.048
2008 Carson D, Margrain TH, Patel A. New approach to evaluate retinal protection by intraocular lenses against age-related lipofuscin accumulation-mediated retinal phototoxicity. Journal of Cataract and Refractive Surgery. 34: 1785-92. PMID 18812134 DOI: 10.1016/j.jcrs.2008.06.034  0.044
2012 Shi L, Ramsay S, Ermis R, Carson D. pH in the bacteria-contaminated wound and its impact on clostridium histolyticum collagenase activity: implications for the use of collagenase wound debridement agents. Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society. 38: 514-21. PMID 21860332 DOI: 10.1097/WON.0b013e31822ad034  0.043
2011 Shi L, Ramsay S, Ermis R, Carson D. In vitro and in vivo studies on matrix metalloproteinases interacting with small intestine submucosa wound matrix. International Wound Journal. 9: 44-53. PMID 21883934 DOI: 10.1111/j.1742-481X.2011.00843.x  0.042
2008 Lang TF, Cardy D, Carson D, Loughrey CM, Hanna E. Audit of acute hypoglycaemia in children: re-audit of procedures for diagnosis. Annals of Clinical Biochemistry. 45: 486-8. PMID 18753421 DOI: 10.1258/acb.2008.008037  0.037
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