Priyamvada Rai, Ph.D.

Affiliations: 
2003 University of California, Berkeley, Berkeley, CA, United States 
Area:
Biophysical Chemistry: Proteins, Nucleic Acids, NMR Spectroscopy
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"Priyamvada Rai"
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David E. Wemmer grad student 2003 UC Berkeley
 (Part I. NMR studies of sequence-specific transition metal binding to biologically important DNA sequences cleaved during the iron-mediated Fenton reaction. Part II. DNA sequence-dependent steady-state and time-resolved fluorescence characteristics of 2-)
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Publications

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Zhang L, Misiara L, Samaranayake GJ, et al. (2021) OGG1 co-inhibition antagonizes the tumor-inhibitory effects of targeting MTH1. Redox Biology. 40: 101848
Samaranayake GJ, Troccoli CI, Zhang L, et al. (2019) The existence of MTH1-independent 8-oxodGTPase activity in cancer cells as a compensatory mechanism against on-target effects of MTH1 inhibitors. Molecular Cancer Therapeutics
McPherson LA, Troccoli CI, Ji D, et al. (2019) Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue. Dna Repair. 102644
Zhu Y, Liu J, Park J, et al. (2019) Subcellular compartmentalization of NAD and its role in cancer: A sereNADe of metabolic melodies. Pharmacology & Therapeutics
Rai P, Sobol RW. (2019) Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleotide pool to genotoxic damage. Dna Repair. 77: 18-26
Nagathihalli NS, Castellanos J, Lamichhane P, et al. (2018) Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer. Cancer Research
Samaranayake GJ, Troccoli CI, Huynh MQ, et al. (2018) Abstract B032: Inappropriate AR reactivation-induced redox stress as a novel therapeutic target in castration-resistant prostate cancer Cancer Research. 78
Troccoli C, Lyles R, Samaranayake G, et al. (2018) The ROS duality in castration-resistant prostate cancer emergence and progression Free Radical Biology and Medicine. 128: S75
Rai P. (2018) Towards a better understanding of human MutT Homolog 1 (MTH1) as a therapeutic target in cancer Free Radical Biology and Medicine. 128
Samaranayake GJ, Troccoli CI, Huynh M, et al. (2017) Thioredoxin-1 protects against androgen receptor-induced redox vulnerability in castration-resistant prostate cancer. Nature Communications. 8: 1204
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