Raymond A. Sobel, MD

Pathology Stanford University, Palo Alto, CA 
Cellular and molecular mechanisms of immune responses in the central nervous system; multiple sclerosis.
"Raymond Sobel"
Cross-listing: Neurotree

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Wang C, Yosef N, Gaublomme J, et al. (2015) CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity. Cell
Graham KL, Zhang JV, Lewén S, et al. (2014) A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease. Plos One. 9: e112925
Massilamany C, Marciano-Cabral F, Rocha-Azevedo Bd, et al. (2014) SJL mice infected with Acanthamoeba castellanii develop central nervous system autoimmunity through the generation of cross-reactive T cells for myelin antigens. Plos One. 9: e98506
Wang D, Bhat R, Sobel RA, et al. (2014) Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). Drug Development Research. 75: 172-88
Molnarfi N, Schulze-Topphoff U, Weber MS, et al. (2013) MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. The Journal of Experimental Medicine. 210: 2921-37
Hsu JL, Khan MA, Sobel RA, et al. (2013) Aspergillus fumigatus invasion increases with progressive airway ischemia. Plos One. 8: e77136
Garris CS, Wu L, Acharya S, et al. (2013) Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation. Nature Immunology. 14: 1166-72
Kurnellas MP, Adams CM, Sobel RA, et al. (2013) Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation. Science Translational Medicine. 5: 179ra42
Lee Y, Awasthi A, Yosef N, et al. (2012) Induction and molecular signature of pathogenic TH17 cells. Nature Immunology. 13: 991-9
Kurnellas MP, Brownell SE, Su L, et al. (2012) Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis. The Journal of Biological Chemistry. 287: 36423-34
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