Amanda L. Woerman, Ph.D. - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
neurodegenerative disease, tau, synuclein, protein misfolding

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Khedmatgozar CR, Holec SAM, Woerman AL. The role of α-synuclein prion strains in Parkinson's disease and multiple system atrophy. Plos Pathogens. 20: e1011920. PMID 38271292 DOI: 10.1371/journal.ppat.1011920  0.351
2023 Zeng Z, Vijayan V, Tsay K, Frost MP, Quddus A, Albert A, Vigers M, Woerman AL, Han S. CBD and PSP cell-passaged Tau Seeds Generate Heterogeneous Fibrils with A sub-population Adopting Disease Folds. Biorxiv : the Preprint Server For Biology. PMID 37502998 DOI: 10.1101/2023.07.19.549721  0.422
2022 Holec SAM, Lee J, Oehler A, Batia L, Wiggins-Gamble A, Lau J, Ooi FK, Merz GE, Wang M, Mordes DA, Olson SH, Woerman AL. The E46K mutation modulates α-synuclein prion replication in transgenic mice. Plos Pathogens. 18: e1010956. PMID 36454879 DOI: 10.1371/journal.ppat.1010956  0.506
2022 Holec SAM, Lee J, Oehler A, Ooi FK, Mordes DA, Olson SH, Prusiner SB, Woerman AL. Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein. Acta Neuropathologica. PMID 36018376 DOI: 10.1007/s00401-022-02476-7  0.636
2022 Holec SAM, Liu SL, Woerman AL. Consequences of variability in α-synuclein fibril structure on strain biology. Acta Neuropathologica. 143: 311-330. PMID 35122113 DOI: 10.1007/s00401-022-02403-w  0.448
2022 Ayers JI, Lee J, Monteiro O, Woerman AL, Lazar AA, Condello C, Paras NA, Prusiner SB. Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35115402 DOI: 10.1073/pnas.2113489119  0.734
2022 Woerman AL, Tamgüney G. Body-first Parkinson's disease and variant Creutzfeldt-Jakob disease - similar or different? Neurobiology of Disease. 164: 105625. PMID 35026401 DOI: 10.1016/j.nbd.2022.105625  0.508
2021 Lester E, Ooi FK, Bakkar N, Ayers J, Woerman AL, Wheeler J, Bowser R, Carlson GA, Prusiner SB, Parker R. Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components. Neuron. PMID 33848474 DOI: 10.1016/j.neuron.2021.03.026  0.541
2020 Holec SAM, Woerman AL. Evidence of distinct α-synuclein strains underlying disease heterogeneity. Acta Neuropathologica. PMID 32440702 DOI: 10.1007/s00401-020-02163-5  0.48
2020 Woerman AL, Patel S, Kazmi SA, Oehler A, Lee J, Mordes DA, Olson SH, Prusiner SB. Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy. Plos Pathogens. 16: e1008222. PMID 32017806 DOI: 10.1371/Journal.Ppat.1008222  0.673
2019 Wang X, Williams D, Müller I, Lemieux M, Dukart R, Maia IBL, Wang H, Woerman AL, Schmitt-Ulms G. Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins. Scientific Reports. 9: 16238. PMID 31700063 DOI: 10.1038/S41598-019-52543-5  0.656
2019 Aoyagi A, Condello C, Stöhr J, Yue W, Rivera BM, Lee JC, Woerman AL, Halliday G, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Keene CD, Seeley WW, et al. Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain. Science Translational Medicine. 11. PMID 31043574 DOI: 10.1126/Scitranslmed.Aat8462  0.715
2019 Woerman AL, Oehler A, Kazmi SA, Lee J, Halliday GM, Middleton LT, Gentleman SM, Mordes DA, Spina S, Grinberg LT, Olson SH, Prusiner SB. Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines. Acta Neuropathologica. PMID 30690664 DOI: 10.1007/S00401-019-01959-4  0.649
2017 Woerman AL, Kazmi SA, Patel S, Aoyagi A, Oehler A, Widjaja K, Mordes DA, Olson SH, Prusiner SB. Familial Parkinson's point mutation abolishes multiple system atrophy prion replication. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279394 DOI: 10.1073/Pnas.1719369115  0.627
2017 Woerman AL, Patel S, Kazmi SA, Oehler A, Freyman Y, Espiritu L, Cotter R, Castaneda JA, Olson SH, Prusiner SB. Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines. Jama Neurology. PMID 29059326 DOI: 10.1001/Jamaneurol.2017.2822  0.603
2017 Woerman AL, Kazmi SA, Patel S, Freyman Y, Oehler A, Aoyagi A, Mordes DA, Halliday GM, Middleton LT, Gentleman SM, Olson SH, Prusiner SB. MSA prions exhibit remarkable stability and resistance to inactivation. Acta Neuropathologica. PMID 28849371 DOI: 10.1007/S00401-017-1762-2  0.67
2017 Woerman AL. The importance of developing strain-specific models of neurodegenerative disease. Acta Neuropathologica. PMID 28786000 DOI: 10.1007/S00401-017-1761-3  0.411
2017 Giles K, Woerman AL, Berry DB, Prusiner SB. Bioassays and Inactivation of Prions. Cold Spring Harbor Perspectives in Biology. PMID 28246183 DOI: 10.1101/Cshperspect.A023499  0.618
2017 Woerman AL, Watts JC, Aoyagi A, Giles K, Middleton LT, Prusiner SB. α-Synuclein: Multiple System Atrophy Prions. Cold Spring Harbor Perspectives in Medicine. PMID 28213437 DOI: 10.1101/Cshperspect.A024588  0.743
2016 Woerman AL, Aoyagi A, Patel S, Kazmi SA, Lobach I, Grinberg LT, McKee AC, Seeley WW, Olson SH, Prusiner SB. Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911827 DOI: 10.1073/Pnas.1616344113  0.574
2015 Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB, Patel S, Oehler A, Lowe JK, Kravitz SN, Geschwind DH, Glidden DV, Halliday GM, Middleton LT, Gentleman SM, et al. Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 112: E5308-17. PMID 26324905 DOI: 10.1073/Pnas.1514475112  0.748
2015 Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, et al. Propagation of prions causing synucleinopathies in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E4949-58. PMID 26286986 DOI: 10.1073/Pnas.1513426112  0.754
2013 Woerman AL, Mendelowitz D. Postnatal sulfur dioxide exposure reversibly alters parasympathetic regulation of heart rate. Hypertension. 62: 274-80. PMID 23774227 DOI: 10.1161/Hypertensionaha.113.01552  0.566
2013 Gorini C, Jameson H, Woerman AL, Perry DC, Mendelowitz D. Prenatal nicotine exposure enhances the trigeminocardiac reflex via serotonin receptor facilitation in brainstem pathways. Journal of Applied Physiology (Bethesda, Md. : 1985). 115: 415-21. PMID 23766497 DOI: 10.1152/Japplphysiol.00552.2013  0.686
2013 Woerman AL, Mendelowitz D. Perinatal sulfur dioxide exposure alters brainstem parasympathetic control of heart rate. Cardiovascular Research. 99: 16-23. PMID 23504550 DOI: 10.1093/Cvr/Cvt057  0.577
2012 Boychuk CR, Woerman AL, Mendelowitz D. Modulation of bulbospinal rostral ventral lateral medulla neurons by hypoxia/hypercapnia but not medullary respiratory activity. Hypertension. 60: 1491-7. PMID 23108653 DOI: 10.1161/Hypertensionaha.112.197954  0.564
2006 Condello C, Aoyagi A, Stöhr J, Lee JC, Rivera BM, Woerman AL, Halliday GM, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Dirk Keene C, Seeley WW, DeGrado WF, et al. P4-233: AGED ALZHEIMER'S DISEASE BRAINS EXHIBIT NUMEROUS Aβ BUT ONLY FEW TAU PRIONS Alzheimer's & Dementia. 14: P1531-P1532. DOI: 10.1016/J.Jalz.2018.07.054  0.709
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