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Nina Liu, Ph.D. - Publications

Affiliations: 
2011 Chemistry Stony Brook University, Stony Brook, NY, United States 
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Fernández de Luco J, Recio-Balsells AI, Ghiano DG, Bortolotti A, Belardinelli JM, Liu N, Hoffmann P, Lherbet C, Tonge PJ, Tekwani B, Morbidoni HR, Labadie GR. Exploring the chemical space of 1,2,3-triazolyl triclosan analogs for discovery of new antileishmanial chemotherapeutic agents. Rsc Medicinal Chemistry. 12: 120-128. PMID 34046604 DOI: 10.1039/d0md00291g  0.634
2016 Ghiano DG, de la Iglesia A, Liu N, Tonge PJ, Morbidoni HR, Labadie GR. Antitubercular activity of 1,2,3-triazolyl fatty acid derivatives. European Journal of Medicinal Chemistry. 125: 842-852. PMID 27750201 DOI: 10.1016/J.Ejmech.2016.09.086  0.621
2016 Neckles CM, Pschibul A, Lai CE, Hirschbeck M, Kuper J, Davoodi S, Zou J, Liu N, Pan P, Shah S, Daryaee F, Bommineni GR, Lai C, Simmerling C, Kisker C, et al. Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase FabV. Biochemistry. PMID 27136302 DOI: 10.1021/Acs.Biochem.5B01301  0.72
2015 Yu W, Neckles C, Chang A, Bommineni GR, Spagnuolo L, Zhang Z, Liu N, Lai C, Truglio J, Tonge PJ. A [(32)P]NAD(+)-based method to identify and quantitate long residence time enoyl-acyl carrier protein reductase inhibitors. Analytical Biochemistry. 474: 40-9. PMID 25684450 DOI: 10.1016/J.Ab.2014.12.022  0.601
2014 Pan P, Knudson SE, Bommineni GR, Li HJ, Lai CT, Liu N, Garcia-Diaz M, Simmerling C, Patil SS, Slayden RA, Tonge PJ. Time-dependent diaryl ether inhibitors of InhA: structure-activity relationship studies of enzyme inhibition, antibacterial activity, and in vivo efficacy. Chemmedchem. 9: 776-91. PMID 24616444 DOI: 10.1002/Cmdc.201300429  0.783
2014 Li HJ, Lai CT, Pan P, Yu W, Liu N, Bommineni GR, Garcia-Diaz M, Simmerling C, Tonge PJ. A structural and energetic model for the slow-onset inhibition of the Mycobacterium tuberculosis enoyl-ACP reductase InhA. Acs Chemical Biology. 9: 986-93. PMID 24527857 DOI: 10.1021/Cb400896G  0.758
2014 Cummings JE, Beaupre AJ, Knudson SE, Liu N, Yu W, Neckles C, Wang H, Khanna A, Bommineni GR, Trunck LA, Schweizer HP, Tonge PJ, Slayden RA. Substituted diphenyl ethers as a novel chemotherapeutic platform against Burkholderia pseudomallei. Antimicrobial Agents and Chemotherapy. 58: 1646-51. PMID 24379198 DOI: 10.1128/Aac.02296-13  0.669
2014 Pan P, Knudson SE, Bommineni GR, Li H, Lai C, Liu N, Garcia-Diaz M, Simmerling C, Patil SS, Slayden RA, Tonge PJ. Cover Picture: Time-Dependent Diaryl Ether Inhibitors of InhA: Structure-Activity Relationship Studies of Enzyme Inhibition, Antibacterial Activity, and in vivo Efficacy (ChemMedChem 4/2014) Chemmedchem. 9: 673-673. DOI: 10.1002/Cmdc.201490010  0.741
2012 Hirschbeck MW, Kuper J, Lu H, Liu N, Neckles C, Shah S, Wagner S, Sotriffer CA, Tonge PJ, Kisker C. Structure of the Yersinia pestis FabV enoyl-ACP reductase and its interaction with two 2-pyridone inhibitors. Structure (London, England : 1993). 20: 89-100. PMID 22244758 DOI: 10.1016/J.Str.2011.07.019  0.715
2011 Li X, Liu N, Zhang H, Knudson SE, Li HJ, Lai CT, Simmerling C, Slayden RA, Tonge PJ. CoA Adducts of 4-Oxo-4-Phenylbut-2-enoates: Inhibitors of MenB from the M. tuberculosis Menaquinone Biosynthesis Pathway. Acs Medicinal Chemistry Letters. 2: 818-823. PMID 22267981 DOI: 10.1021/Ml200141E  0.772
2011 Li HJ, Li X, Liu N, Zhang H, Truglio JJ, Mishra S, Kisker C, Garcia-Diaz M, Tonge PJ. Mechanism of the intramolecular Claisen condensation reaction catalyzed by MenB, a crotonase superfamily member. Biochemistry. 50: 9532-44. PMID 21830810 DOI: 10.1021/Bi200877X  0.725
2011 Kinnings SL, Liu N, Tonge PJ, Jackson RM, Xie L, Bourne PE. Correction to "Machine learning-based method to improve docking scoring functions and its application to drug repurposing". Journal of Chemical Information and Modeling. 51: 1195-7. PMID 21526828 DOI: 10.1021/Ci2001346  0.494
2011 Liu N, Cummings JE, England K, Slayden RA, Tonge PJ. Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomallei. The Journal of Antimicrobial Chemotherapy. 66: 564-73. PMID 21393229 DOI: 10.1093/Jac/Dkq509  0.632
2011 Kinnings SL, Liu N, Tonge PJ, Jackson RM, Xie L, Bourne PE. A machine learning-based method to improve docking scoring functions and its application to drug repurposing. Journal of Chemical Information and Modeling. 51: 408-19. PMID 21291174 DOI: 10.1021/Ci100369F  0.588
2010 Li X, Liu N, Zhang H, Knudson SE, Slayden RA, Tonge PJ. Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters. 20: 6306-9. PMID 20850304 DOI: 10.1016/J.Bmcl.2010.08.076  0.743
2010 Luckner SR, Liu N, am Ende CW, Tonge PJ, Kisker C. A slow, tight binding inhibitor of InhA, the enoyl-acyl carrier protein reductase from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 285: 14330-7. PMID 20200152 DOI: 10.1074/Jbc.M109.090373  0.707
2009 Kinnings SL, Liu N, Buchmeier N, Tonge PJ, Xie L, Bourne PE. Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis. Plos Computational Biology. 5: e1000423. PMID 19578428 DOI: 10.1371/Journal.Pcbi.1000423  0.636
2008 am Ende CW, Knudson SE, Liu N, Childs J, Sullivan TJ, Boyne M, Xu H, Gegina Y, Knudson DL, Johnson F, Peloquin CA, Slayden RA, Tonge PJ. Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 3029-33. PMID 18457948 DOI: 10.1016/J.Bmcl.2008.04.038  0.723
2007 Bonnac L, Gao GY, Chen L, Felczak K, Bennett EM, Xu H, Kim T, Liu N, Oh H, Tonge PJ, Pankiewicz KW. Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters. 17: 4588-91. PMID 17560106 DOI: 10.1016/J.Bmcl.2007.05.084  0.648
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