Shu G. Chen, PhD - Publications

Pathology Case Western Reserve University, Cleveland Heights, OH, United States 

92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bargar C, Wang W, Gunzler SA, LeFevre A, Wang Z, Lerner AJ, Singh N, Tatsuoka C, Appleby B, Zhu X, Xu R, Haroutunian V, Zou WQ, Ma J, Chen SG. Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson's disease and dementia with Lewy bodies. Acta Neuropathologica Communications. 9: 62. PMID 33827706 DOI: 10.1186/s40478-021-01175-w  1
2020 Wang Z, Becker K, Donadio V, Siedlak S, Yuan J, Rezaee M, Incensi A, Kuzkina A, Orrú CD, Tatsuoka C, Liguori R, Gunzler SA, Caughey B, Jimenez-Capdeville ME, Zhu X, ... ... Chen SG, et al. Skin α-Synuclein Aggregation Seeding Activity as a Novel Biomarker for Parkinson Disease. Jama Neurology. PMID 32986090 DOI: 10.1001/jamaneurol.2020.3311  1
2019 Schaffner A, Li X, Gomez-Llorente Y, Leandrou E, Memou A, Clemente N, Yao C, Afsari F, Zhi L, Pan N, Morohashi K, Hua X, Zhou MM, Wang C, Zhang H, ... Chen SG, et al. Vitamin B modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection. Cell Research. PMID 30858560 DOI: 10.1038/S41422-019-0153-8  0.4
2018 Yan T, Wang L, Gao J, Siedlak SL, Huntley ML, Termsarasab P, Perry G, Chen SG, Wang X. Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29562525 DOI: 10.3233/Jad-180023  1
2017 Cracco L, Notari S, Cali I, Sy MS, Chen SG, Cohen ML, Ghetti B, Appleby BS, Zou WQ, Caughey B, Safar JG, Gambetti P. Novel strain properties distinguishing sporadic prion diseases sharing prion protein genotype and prion type. Scientific Reports. 7: 38280. PMID 28091514 DOI: 10.1038/Srep38280  1
2015 Safar JG, Xiao X, Kabir ME, Chen S, Kim C, Haldiman T, Cohen Y, Chen W, Cohen ML, Surewicz WK. Structural determinants of phenotypic diversity and replication rate of human prions. Plos Pathogens. 11: e1004832. PMID 25875953 DOI: 10.1371/Journal.Ppat.1004832  1
2015 Tripathi AK, Haldar S, Qian J, Beserra A, Suda S, Singh A, Hopfer U, Chen SG, Garrick MD, Turner JR, Knutson MD, Singh N. Prion protein functions as a ferrireductase partner for ZIP14 and DMT1. Free Radical Biology & Medicine. 84: 322-30. PMID 25862412 DOI: 10.1016/J.Freeradbiomed.2015.03.037  1
2015 Johnson WM, Yao C, Siedlak SL, Wang W, Zhu X, Caldwell GA, Wilson-Delfosse AL, Mieyal JJ, Chen SG. Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease. Human Molecular Genetics. 24: 1322-35. PMID 25355420 DOI: 10.1093/Hmg/Ddu542  1
2014 Nieznanski K, Surewicz K, Chen S, Nieznanska H, Surewicz WK. Interaction between prion protein and Aβ amyloid fibrils revisited. Acs Chemical Neuroscience. 5: 340-5. PMID 24669873 DOI: 10.1021/Cn500019C  1
2014 Cobb NJ, Apostol MI, Chen S, Smirnovas V, Surewicz WK. Conformational stability of mammalian prion protein amyloid fibrils is dictated by a packing polymorphism within the core region. The Journal of Biological Chemistry. 289: 2643-50. PMID 24338015 DOI: 10.1074/Jbc.M113.520718  1
2013 Dutta A, Chen S, Surewicz WK. The effect of β2-α2 loop mutation on amyloidogenic properties of the prion protein. Febs Letters. 587: 2918-23. PMID 23892077 DOI: 10.1016/J.Febslet.2013.07.023  1
2013 Yao C, Johnson WM, Gao Y, Wang W, Zhang J, Deak M, Alessi DR, Zhu X, Mieyal JJ, Roder H, Wilson-Delfosse AL, Chen SG. Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity. Human Molecular Genetics. 22: 328-44. PMID 23065705 DOI: 10.1093/Hmg/Dds431  1
2012 Nieznanski K, Choi JK, Chen S, Surewicz K, Surewicz WK. Soluble prion protein inhibits amyloid-β (Aβ) fibrillization and toxicity. The Journal of Biological Chemistry. 287: 33104-8. PMID 22915585 DOI: 10.1074/Jbc.C112.400614  1
2012 Notari S, Qing L, Pocchiari M, Dagdanova A, Hatcher K, Dogterom A, Groisman JF, Lumholtz IB, Puopolo M, Lasmezas C, Chen SG, Kong Q, Gambetti P. Assessing prion infectivity of human urine in sporadic Creutzfeldt-Jakob disease. Emerging Infectious Diseases. 18: 21-8. PMID 22260924 DOI: 10.3201/Eid1801.110589  1
2012 Wang X, Yan MH, Fujioka H, Liu J, Wilson-Delfosse A, Chen SG, Perry G, Casadesus G, Zhu X. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Human Molecular Genetics. 21: 1931-44. PMID 22228096 DOI: 10.1093/Hmg/Dds003  1
2011 Jones EM, Wu B, Surewicz K, Nadaud PS, Helmus JJ, Chen S, Jaroniec CP, Surewicz WK. Structural polymorphism in amyloids: new insights from studies with Y145Stop prion protein fibrils. The Journal of Biological Chemistry. 286: 42777-84. PMID 22002245 DOI: 10.1074/Jbc.M111.302539  1
2011 Wang P, Hatcher KL, Bartz JC, Chen SG, Skinner P, Richt J, Liu H, Sreevatsan S. Selection and characterization of DNA aptamers against PrP(Sc). Experimental Biology and Medicine (Maywood, N.J.). 236: 466-76. PMID 21444369 DOI: 10.1258/Ebm.2011.010323  1
2011 Castellani RJ, Nugent SL, Morrison AL, Zhu X, Lee HG, Harris PL, Bajić V, Sharma HS, Chen SG, Oettgen P, Perry G, Smith MA. CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 23-6. PMID 20972807 DOI: 10.1007/S00702-010-0485-5  1
2010 Dagdanova A, Ilchenko S, Notari S, Yang Q, Obrenovich ME, Hatcher K, McAnulty P, Huang L, Zou W, Kong Q, Gambetti P, Chen SG. Characterization of the prion protein in human urine. The Journal of Biological Chemistry. 285: 30489-95. PMID 20670940 DOI: 10.1074/Jbc.M110.161794  1
2010 Das D, Luo X, Singh A, Gu Y, Ghosh S, Mukhopadhyay CK, Chen SG, Sy MS, Kong Q, Singh N. Paradoxical role of prion protein aggregates in redox-iron induced toxicity. Plos One. 5: e11420. PMID 20625431 DOI: 10.1371/Journal.Pone.0011420  1
2010 Chen S, Yadav SP, Surewicz WK. Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues. The Journal of Biological Chemistry. 285: 26377-83. PMID 20576610 DOI: 10.1074/Jbc.M110.145516  1
2010 Yao C, El Khoury R, Wang W, Byrd TA, Pehek EA, Thacker C, Zhu X, Smith MA, Wilson-Delfosse AL, Chen SG. LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease. Neurobiology of Disease. 40: 73-81. PMID 20382224 DOI: 10.1016/J.Nbd.2010.04.002  1
2010 Lee HP, Zhu X, Liu G, Chen SG, Perry G, Smith MA, Lee HG. Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship. Cell Research. 20: 397-9. PMID 20357807 DOI: 10.1038/Cr.2010.39  1
2010 Zou WQ, Langeveld J, Xiao X, Chen S, McGeer PL, Yuan J, Payne MC, Kang HE, McGeehan J, Sy MS, Greenspan NS, Kaplan D, Wang GX, Parchi P, Hoover E, et al. PrP conformational transitions alter species preference of a PrP-specific antibody. The Journal of Biological Chemistry. 285: 13874-84. PMID 20194495 DOI: 10.1074/Jbc.M109.088831  1
2010 Drawz SM, Bethel CR, Doppalapudi VR, Sheri A, Pagadala SR, Hujer AM, Skalweit MJ, Anderson VE, Chen SG, Buynak JD, Bonomo RA. Penicillin sulfone inhibitors of class D beta-lactamases. Antimicrobial Agents and Chemotherapy. 54: 1414-24. PMID 20086146 DOI: 10.1128/Aac.00743-09  1
2010 Zou WQ, Langeveld J, Xiao X, Chen S, McGeer PL, Yuan J, Payne MC, Kang HE, McGeehan J, Sy MS, Greenspan NS, Kaplan D, Wang GX, Parchi P, Hoover E, et al. Reply to Kascsak: Definition of the PrP 3F4 epitope revisited Journal of Biological Chemistry. 285: le6. DOI: 10.1074/Jbc.N109.088831  1
2009 Su B, Liu H, Wang X, Chen SG, Siedlak SL, Kondo E, Choi R, Takeda A, Castellani RJ, Perry G, Smith MA, Zhu X, Lee HG. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Molecular Neurodegeneration. 4: 32. PMID 19627592 DOI: 10.1186/1750-1326-4-32  1
2009 Hatcher K, Zheng J, Chen SG. Cryptic peptides of the kringle domains preferentially bind to disease-associated prion protein. Journal of Alzheimer's Disease : Jad. 16: 421-31. PMID 19221431 DOI: 10.3233/Jad-2009-0980  1
2009 Gandhi PN, Chen SG, Wilson-Delfosse AL. Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease. Journal of Neuroscience Research. 87: 1283-95. PMID 19025767 DOI: 10.1002/Jnr.21949  1
2009 Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. Journal of Cellular and Molecular Medicine. 13: 320-33. PMID 18373733 DOI: 10.1111/J.1582-4934.2008.00324.X  1
2008 Perry G, Zhu X, Babar AK, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Chen SG. Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies. Neuro-Degenerative Diseases. 5: 222-4. PMID 18322396 DOI: 10.1159/000113708  1
2008 Gandhi PN, Wang X, Zhu X, Chen SG, Wilson-Delfosse AL. The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules. Journal of Neuroscience Research. 86: 1711-20. PMID 18214993 DOI: 10.1002/Jnr.21622  1
2007 Guo L, Gandhi PN, Wang W, Petersen RB, Wilson-Delfosse AL, Chen SG. The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity. Experimental Cell Research. 313: 3658-70. PMID 17706965 DOI: 10.1016/J.Yexcr.2007.07.007  1
2007 Xu M, Yamada M, Li M, Liu H, Chen SG, Han YW. FadA from Fusobacterium nucleatum utilizes both secreted and nonsecreted forms for functional oligomerization for attachment and invasion of host cells. The Journal of Biological Chemistry. 282: 25000-9. PMID 17588948 DOI: 10.1074/jbc.M611567200  1
2007 Huang S, Liang J, Zheng M, Li X, Wang M, Wang P, Vanegas D, Wu D, Chakraborty B, Hays AP, Chen K, Chen SG, Booth S, Cohen M, Gambetti P, et al. Inducible overexpression of wild-type prion protein in the muscles leads to a primary myopathy in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 6800-5. PMID 17420473 DOI: 10.1073/Pnas.0608885104  1
2006 Hatcher K, Harris C, Gambetti P, Chen SG. Advances in Prion Disease Surveillance. Advances in Clinical Chemistry. 41: 263-292. PMID 28682752 DOI: 10.1016/S0065-2423(05)41008-2  1
2006 Zhu X, Babar A, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Perry G, Chen SG. LRRK2 in Parkinson's disease and dementia with Lewy bodies. Molecular Neurodegeneration. 1: 17. PMID 17137507 DOI: 10.1186/1750-1326-1-17  1
2006 Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotoxicity Research. 10: 43-56. PMID 17000469 DOI: 10.1007/Bf03033333  1
2006 Zhu X, Siedlak SL, Smith MA, Perry G, Chen SG. LRRK2 protein is a component of Lewy bodies. Annals of Neurology. 60: 617-8; author reply . PMID 16847950 DOI: 10.1002/Ana.20928  1
2006 Colucci M, Moleres FJ, Xie ZL, Ray-Chaudhury A, Gutti S, Butefisch CM, Cervenakova L, Wang W, Goldfarb LG, Kong Q, Ghetti B, Chen SG, Gambetti P. Gerstmann-Sträussler-Scheinker: a new phenotype with 'curly' PrP deposits. Journal of Neuropathology and Experimental Neurology. 65: 642-51. PMID 16825951 DOI: 10.1097/01.Jnen.0000228198.81797.4D  1
2006 Guo L, Wang W, Chen SG. Leucine-rich repeat kinase 2: relevance to Parkinson's disease. The International Journal of Biochemistry & Cell Biology. 38: 1469-75. PMID 16600664 DOI: 10.1016/j.biocel.2006.02.009  1
2006 Lee DC, Sakudo A, Kim CK, Nishimura T, Saeki K, Matsumoto Y, Yokoyama T, Chen SG, Itohara S, Onodera T. Fusion of Doppel to octapeptide repeat and N-terminal half of hydrophobic region of prion protein confers resistance to serum deprivation. Microbiology and Immunology. 50: 203-9. PMID 16547418 DOI: JST.JSTAGE/mandi/50.203  1
2006 Takemura K, Wang P, Vorberg I, Surewicz W, Priola SA, Kanthasamy A, Pottathil R, Chen SG, Sreevatsan S. DNA aptamers that bind to PrP(C) and not PrP(Sc) show sequence and structure specificity. Experimental Biology and Medicine (Maywood, N.J.). 231: 204-14. PMID 16446497 DOI: 10.1177/153537020623100211  1
2006 Xie Z, O'Rourke KI, Dong Z, Jenny AL, Langenberg JA, Belay ED, Schonberger LB, Petersen RB, Zou W, Kong Q, Gambetti P, Chen SG. Chronic wasting disease of elk and deer and Creutzfeldt-Jakob disease: comparative analysis of the scrapie prion protein. The Journal of Biological Chemistry. 281: 4199-206. PMID 16338930 DOI: 10.1074/Jbc.M509052200  1
2006 Hatcher K, Harris C, Gambetti P, Chen SG. Advances in Prion Disease Surveillance Advances in Clinical Chemistry. 41: 263-292. DOI: 10.1016/S0065-2423(05)41008-2  1
2005 Pastore M, Chin SS, Bell KL, Dong Z, Yang Q, Yang L, Yuan J, Chen SG, Gambetti P, Zou WQ. Creutzfeldt-Jakob disease (CJD) with a mutation at codon 148 of prion protein gene: relationship with sporadic CJD. The American Journal of Pathology. 167: 1729-38. PMID 16314483 DOI: 10.1016/S0002-9440(10)61254-0  1
2005 Kong Q, Huang S, Zou W, Vanegas D, Wang M, Wu D, Yuan J, Zheng M, Bai H, Deng H, Chen K, Jenny AL, O'Rourke K, Belay ED, Schonberger LB, ... ... Chen SG, et al. Chronic wasting disease of elk: transmissibility to humans examined by transgenic mouse models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7944-9. PMID 16135751 DOI: 10.1523/Jneurosci.2467-05.2005  1
2005 Narang HK, Dagdanova A, Xie Z, Yang Q, Chen SG. Sensitive detection of prion protein in human urine. Experimental Biology and Medicine (Maywood, N.J.). 230: 343-9. PMID 15855301 DOI: 10.1177/153537020523000508  1
2005 Aliyev A, Chen SG, Seyidova D, Smith MA, Perry G, de la Torre J, Aliev G. Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease. Journal of the Neurological Sciences. 229: 285-92. PMID 15760652 DOI: 10.1016/J.Jns.2004.11.040  1
2004 Mishra RS, Basu S, Gu Y, Luo X, Zou WQ, Mishra R, Li R, Chen SG, Gambetti P, Fujioka H, Singh N. Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11280-90. PMID 15601934 DOI: 10.1523/Jneurosci.2864-04.2004  1
2004 Castellani RJ, Colucci M, Xie Z, Zou W, Li C, Parchi P, Capellari S, Pastore M, Rahbar MH, Chen SG, Gambetti P. Sensitivity of 14-3-3 protein test varies in subtypes of sporadic Creutzfeldt-Jakob disease. Neurology. 63: 436-42. PMID 15304573 DOI: 10.1212/01.Wnl.0000135153.96325.3B  1
2004 Aliyev A, Seyidova D, Rzayev N, Obrenovich ME, Lamb BT, Chen SG, Smith MA, Perry G, de la Torre JC, Aliev G. Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease? Neurological Research. 26: 547-53. PMID 15265272 DOI: 10.1179/01610425017613  1
2004 Zou WQ, Zheng J, Gray DM, Gambetti P, Chen SG. Antibody to DNA detects scrapie but not normal prion protein. Proceedings of the National Academy of Sciences of the United States of America. 101: 1380-5. PMID 14734804 DOI: 10.1073/Pnas.0307825100  1
2004 Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, Smith MA, Chen SG, Bush AI. Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry. 43: 560-8. PMID 14717612 DOI: 10.1021/Bi0358824  1
2003 Gambetti P, Kong Q, Zou W, Parchi P, Chen SG. Sporadic and familial CJD: classification and characterisation. British Medical Bulletin. 66: 213-39. PMID 14522861 DOI: 10.1093/Bmb/66.1.213  1
2003 Zou WQ, Capellari S, Parchi P, Sy MS, Gambetti P, Chen SG. Identification of novel proteinase K-resistant C-terminal fragments of PrP in Creutzfeldt-Jakob disease. The Journal of Biological Chemistry. 278: 40429-36. PMID 12917418 DOI: 10.1074/Jbc.M308550200  1
2003 Gambetti P, Parchi P, Chen SG. Hereditary Creutzfeldt-Jakob disease and fatal familial insomnia. Clinics in Laboratory Medicine. 23: 43-64. PMID 12733424 DOI: 10.1016/S0272-2712(02)00065-3  1
2003 Zou W, Colucci M, Gambetti P, Chen SG. Characterization of prion proteins. Methods in Molecular Biology (Clifton, N.J.). 217: 305-14. PMID 12491943 DOI: 10.1385/1-59259-330-5:305  1
2002 Chen SG, Gambetti P. A journey through the species barrier. Neuron. 34: 854-6. PMID 12086631 DOI: 10.1016/S0896-6273(02)00736-5  1
2002 Wu X, Chen SG, Petrash JM, Monnier VM. Alteration of substrate selectivity through mutation of two arginine residues in the binding site of amadoriase II from Aspergillus sp. Biochemistry. 41: 4453-8. PMID 11914093 DOI: 10.1021/Bi025539J  1
2002 Taratuto AL, Piccardo P, Reich EG, Chen SG, Sevlever G, Schultz M, Luzzi AA, Rugiero M, Abecasis G, Endelman M, Garcia AM, Capellari S, Xie Z, Lugaresi E, Gambetti P, et al. Insomnia associated with thalamic involvement in E200K Creutzfeldt-Jakob disease. Neurology. 58: 362-7. PMID 11839833 DOI: 10.1212/Wnl.58.3.362  1
2001 Chen SG. Molecular profiling of paired helical filaments. Journal of Alzheimer's Disease : Jad. 3: 467-9. PMID 22391261 DOI: 10.3233/Jad-2001-3505  1
2001 Gambetti P, Parchi P, Capellari S, Russo C, Tabaton M, Teller JK, Chen SG. Mechanisms of phenotypic heterogeneity in prion, Alzheimer and other conformational diseases. Journal of Alzheimer's Disease : Jad. 3: 87-95. PMID 12214077 DOI: 10.3233/Jad-2001-3113  1
2001 Wong BS, Chen SG, Colucci M, Xie Z, Pan T, Liu T, Li R, Gambetti P, Sy MS, Brown DR. Aberrant metal binding by prion protein in human prion disease. Journal of Neurochemistry. 78: 1400-8. PMID 11579148 DOI: 10.1046/J.1471-4159.2001.00522.X  1
2001 Pan T, Colucci M, Wong BS, Li R, Liu T, Petersen RB, Chen S, Gambetti P, Sy MS. Novel differences between two human prion strains revealed by two-dimensional gel electrophoresis. The Journal of Biological Chemistry. 276: 37284-8. PMID 11489910 DOI: 10.1074/Jbc.M107358200  1
2001 Wong BS, Green AJ, Li R, Xie Z, Pan T, Liu T, Chen SG, Gambetti P, Sy MS. Absence of protease-resistant prion protein in the cerebrospinal fluid of Creutzfeldt-Jakob disease. The Journal of Pathology. 194: 9-14. PMID 11329135 DOI: 10.1002/Path.872  1
2001 Wong BS, Liu T, Paisley D, Li R, Pan T, Chen SG, Perry G, Petersen RB, Smith MA, Melton DW, Gambetti P, Brown DR, Sy MS. Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function. Molecular and Cellular Neurosciences. 17: 768-75. PMID 11312611 DOI: 10.1006/Mcne.2001.0963  1
2001 Chen SG, Zou W, Parchi P, Gambetti P. PrPSc typing by N-terminal sequencing and mass spectrometry Archives of Virology, Supplement. 209-216.  1
2000 Chen SG, Zou W, Parchi P, Gambetti P. PrP(Sc) typing by N-terminal sequencing and mass spectrometry. Archives of Virology. Supplementum. 209-16. PMID 11214924 DOI: 10.1007/978-3-7091-6308-5_20  1
2000 Lu K, Wang W, Xie Z, Wong BS, Li R, Petersen RB, Sy MS, Chen SG. Expression and structural characterization of the recombinant human doppel protein. Biochemistry. 39: 13575-83. PMID 11063595 DOI: 10.1021/Bi001523M  1
2000 Parchi P, Zou W, Wang W, Brown P, Capellari S, Ghetti B, Kopp N, Schulz-Schaeffer WJ, Kretzschmar HA, Head MW, Ironside JW, Gambetti P, Chen SG. Genetic influence on the structural variations of the abnormal prion protein. Proceedings of the National Academy of Sciences of the United States of America. 97: 10168-72. PMID 10963679 DOI: 10.1073/Pnas.97.18.10168  1
2000 Wu X, Takahashi M, Chen SG, Monnier VM. Cloning of amadoriase I isoenzyme from Aspergillus sp.: evidence of FAD covalently linked to Cys342. Biochemistry. 39: 1515-21. PMID 10684633 DOI: 10.1021/Bi992031G  1
2000 Swietnicki W, Morillas M, Chen SG, Gambetti P, Surewicz WK. Aggregation and fibrillization of the recombinant human prion protein huPrP90-231. Biochemistry. 39: 424-31. PMID 10631004 DOI: 10.1021/Bi991967M  1
2000 Chen SG, Parchi P, Gambetti P. 38. Prion diseases including bovine spongiform encephalopathy (mad cow disease) Facts, Research and Intervention in Geriatrics. 2000: 491-502.  1
1999 Goedert M, Spillantini MG, Crowther RA, Chen SG, Parchi P, Tabaton M, Lanska DJ, Markesbery WR, Wilhelmsen KC, Dickson DW, Petersen RB, Gambetti P. Tau gene mutation in familial progressive subcortical gliosis. Nature Medicine. 5: 454-7. PMID 10202939 DOI: 10.1038/7454  1
1998 Russo C, Angelini G, Dapino D, Piccini A, Piombo G, Schettini G, Chen S, Teller JK, Zaccheo D, Gambetti P, Tabaton M. Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 95: 15598-602. PMID 9861015 DOI: 10.1073/Pnas.95.26.15598  1
1998 Parchi P, Petersen RB, Chen SG, Autilio-Gambetti L, Capellari S, Monari L, Cortelli P, Montagna P, Lugaresi E, Gambetti P. Molecular pathology of fatal familial insomnia. Brain Pathology (Zurich, Switzerland). 8: 539-48. PMID 9669705 DOI: 10.1111/J.1750-3639.1998.Tb00176.X  1
1998 Parchi P, Chen SG, Brown P, Zou W, Capellari S, Budka H, Hainfellner J, Reyes PF, Golden GT, Hauw JJ, Gajdusek DC, Gambetti P. Different patterns of truncated prion protein fragments correlate with distinct phenotypes in P102L Gerstmann-Sträussler-Scheinker disease. Proceedings of the National Academy of Sciences of the United States of America. 95: 8322-7. PMID 9653185 DOI: 10.1073/Pnas.95.14.8322  1
1997 Singh N, Zanusso G, Chen SG, Fujioka H, Richardson S, Gambetti P, Petersen RB. Prion protein aggregation reverted by low temperature in transfected cells carrying a prion protein gene mutation. The Journal of Biological Chemistry. 272: 28461-70. PMID 9353306 DOI: 10.1074/Jbc.272.45.28461  1
1997 Chen SG, Parchi P, Brown P, Capellari S, Zou W, Cochran EJ, Vnencak-Jones CL, Julien J, Vital C, Mikol J, Lugaresi E, Autilio-Gambetti L, Gambetti P. Allelic origin of the abnormal prion protein isoform in familial prion diseases. Nature Medicine. 3: 1009-15. PMID 9288728 DOI: 10.1038/Nm0997-1009  1
1997 Raymond GJ, Hope J, Kocisko DA, Priola SA, Raymond LD, Bossers A, Ironside J, Will RG, Chen SG, Petersen RB, Gambetti P, Rubenstein R, Smits MA, Lansbury PT, Caughey B. Molecular assessment of the potential transmissibilities of BSE and scrapie to humans. Nature. 388: 285-8. PMID 9230438 DOI: 10.1038/40876  1
1997 Parchi P, Capellari S, Chen SG, Petersen RB, Gambetti P, Kopp N, Brown P, Kitamoto T, Tateishi J, Giese A, Kretzschmar H. Typing prion isoforms. Nature. 386: 232-4. PMID 9069279 DOI: 10.1038/386232A0  1
1996 Parchi P, Castellani R, Capellari S, Ghetti B, Young K, Chen SG, Farlow M, Dickson DW, Sima AA, Trojanowski JQ, Petersen RB, Gambetti P. Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease. Annals of Neurology. 39: 767-78. PMID 8651649 DOI: 10.1002/Ana.410390613  1
1995 Chen SG, Murakami K. Synergistic activation by cis-fatty acid and diacylglycerol of protein kinase C and protein phosphorylation in hippocampal slices. Neuroscience. 68: 1017-26. PMID 8544978 DOI: 10.1016/0306-4522(95)00175-I  1
1995 Petersen RB, Tabaton M, Chen SG, Monari L, Richardson SL, Lynch T, Manetto V, Lanska DJ, Markesbery WR, Lynches T [corrected to Lynch T]. Familial progressive subcortical gliosis: presence of prions and linkage to chromosome 17. Neurology. 45: 1062-7. PMID 7783864 DOI: 10.1212/Wnl.45.6.1062  1
1995 Gambetti P, Parchi P, Petersen RB, Chen SG, Lugaresi E. Fatal familial insomnia and familial Creutzfeldt-Jakob disease: clinical, pathological and molecular features. Brain Pathology (Zurich, Switzerland). 5: 43-51. PMID 7767490 DOI: 10.1111/J.1750-3639.1995.Tb00576.X  1
1995 Chen SG, Teplow DB, Parchi P, Teller JK, Gambetti P, Autilio-Gambetti L. Truncated forms of the human prion protein in normal brain and in prion diseases. The Journal of Biological Chemistry. 270: 19173-80. PMID 7642585 DOI: 10.1074/Jbc.270.32.19173  1
1995 Parchi P, Castellani R, Cortelli P, Montagna P, Chen SG, Petersen RB, Manetto V, Vnencak-Jones CL, McLean MJ, Sheller JR. Regional distribution of protease-resistant prion protein in fatal familial insomnia. Annals of Neurology. 38: 21-9. PMID 7611720 DOI: 10.1002/Ana.410380107  1
1994 Chen SG, Murakami K. Effects of cis-fatty acid on protein kinase C activation and protein phosphorylation in the hippocampus. Journal of Pharmaceutical Science and Technology : the Official Journal of Pda. 48: 71-5. PMID 8032798  1
1994 Monari L, Chen SG, Brown P, Parchi P, Petersen RB, Mikol J, Gray F, Cortelli P, Montagna P, Ghetti B. Fatal familial insomnia and familial Creutzfeldt-Jakob disease: different prion proteins determined by a DNA polymorphism. Proceedings of the National Academy of Sciences of the United States of America. 91: 2839-42. PMID 7908444 DOI: 10.1073/Pnas.91.7.2839  1
1992 Chen SG, Kulju D, Halt S, Murakami K. Phosphatidylcholine-dependent protein kinase C activation. Effects of cis-fatty acid and diacylglycerol on synergism, autophosphorylation and Ca(2+)-dependency. The Biochemical Journal. 284: 221-6. PMID 1599399  1
1992 Chen SG, Murakami K. Synergistic activation of type III protein kinase C by cis-fatty acid and diacylglycerol. The Biochemical Journal. 282: 33-9. PMID 1311559  1
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