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Craig Michael Horbinski, MD, University of Rochester, PhD, University of Rochester - Publications

Affiliations: 
2015 Pathology and Laboratory Medicine University of Kentucky, Lexington, KY 
 2015- Northwestern University, Evanston, IL 
Area:
Neuropathology, molecucular neuro-oncology, teleneuropathology
Website:
http://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=33419

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Arrieta VA, Duerinck J, Burdett KB, Habashy KJ, Geens W, Gould A, Schwarze JK, Dmello C, Kim KS, Saganty R, Chen L, Moscona A, McCord M, Lee-Chang C, Horbinski CM, et al. ERK1/2 Phosphorylation Predicts Survival in Recurrent Glioblastoma Following Intracerebral and Adjuvant PD-1/CTLA-4 Immunotherapy: A REMARK-Guided Analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37939133 DOI: 10.1158/1078-0432.CCR-23-1889  0.722
2023 McCord M, Jamshidi P, Thirunavu V, Santana-Santos L, Vormittag-Nocito E, Dittman D, Parker S, Baczkowski J, Jennings L, Walshon J, McCortney K, Galbraith K, Zhang H, Lukas RV, Stupp R, ... ... Horbinski C, et al. Variant allelic frequencies of driver mutations can identify gliomas with potentially false-negative MGMT promoter methylation results. Acta Neuropathologica Communications. 11: 175. PMID 37919784 DOI: 10.1186/s40478-023-01680-0  0.737
2023 Johnson M, Bell A, Lauing KL, Ladomersky E, Zhai L, Penco-Campillo M, Shah Y, Mauer E, Xiu J, Nicolaides T, Drumm M, McCortney K, Elemento O, Kim M, Bommi P, ... ... Horbinski C, et al. Advanced age in humans and mouse models of glioblastoma show decreased survival from extratumoral influence. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37725593 DOI: 10.1158/1078-0432.CCR-23-0834  0.714
2023 Budhiraja S, Najem H, Tripathi S, Wadhawani NR, Horbinski C, McCord M, Lenzen AC, Heimberger AB, DeCuypere M. Immunobiology and Cytokine Modulation of the Pediatric Brain Tumor Microenvironment: A Scoping Review. Cancers. 15. PMID 37509316 DOI: 10.3390/cancers15143655  0.73
2023 Drumm M, Wang W, Sears TK, Bell-Burdett K, Javier R, Cotton KY, Webb BT, Byrne KT, Unruh D, Thirunavu V, Walshon J, Steffens A, McCortney K, Lukas RV, Phillips JJ, ... ... Horbinski C, et al. Postoperative risk of IDH mutant glioma-associated seizures and their potential management with IDH mutant inhibitors. The Journal of Clinical Investigation. PMID 37104042 DOI: 10.1172/JCI168035  0.763
2023 Jamshidi P, McCord M, Galbraith K, Santana-Santos L, Jennings LJ, Snuderl M, Horbinski C. Variant allelic frequency of driver mutations predicts success of genomic DNA methylation classification in central nervous system tumors. Acta Neuropathologica. 145: 365-367. PMID 36700952 DOI: 10.1007/s00401-023-02542-8  0.729
2022 McCord M, Bartom E, Burdett K, Baran A, Eckerdt FD, Balyasnikova IV, McCortney K, Sears T, Cheng SY, Sarkaria JN, Stupp R, Heimberger AB, Ahmed A, James CD, Horbinski C. Modeling Therapy-Driven Evolution of Glioblastoma with Patient-Derived Xenografts. Cancers. 14. PMID 36428586 DOI: 10.3390/cancers14225494  0.781
2022 Burdett KB, Unruh D, Drumm M, Steffens A, Lamano JB, Judkins J, Schwartz M, Javier R, Amidei C, Lipp ES, Peters KB, Lai A, Eldred BSC, Heimberger AB, McCortney K, ... ... Horbinski C, et al. Determining venous thromboembolism risk in patients with adult-type diffuse glioma. Blood. PMID 36399711 DOI: 10.1182/blood.2022017858  0.727
2022 Cimino PJ, Ketchum C, Turakulov R, Singh O, Abdullaev Z, Giannini C, Pytel P, Lopez GY, Colman H, Nasrallah MP, Santi M, Fernandes IL, Nirschl J, Dahiya S, Neill S, ... ... Horbinski C, et al. Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1. Acta Neuropathologica. PMID 36271929 DOI: 10.1007/s00401-022-02513-5  0.699
2022 Santana-Santos L, Kam KL, Dittmann D, De Vito S, McCord M, Jamshidi P, Fowler H, Wang X, Aalsburg AM, Brat DJ, Horbinski C, Jennings LJ. Validation of Whole Genome Methylation Profiling Classifier for Central Nervous System Tumors. The Journal of Molecular Diagnostics : Jmd. PMID 35605901 DOI: 10.1016/j.jmoldx.2022.04.009  0.732
2022 Smith HL, Wadhwani N, Horbinski C. Major Features of the 2021 WHO Classification of CNS Tumors. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 35578106 DOI: 10.1007/s13311-022-01249-0  0.521
2022 Arrieta VA, Chen AX, Kane JR, Kang SJ, Kassab C, Dmello C, Zhao J, Burdett KB, Upadhyayula PS, Lee-Chang C, Shilati J, Jaishankar D, Chen L, Gould A, Zhang D, ... ... Horbinski C, et al. Publisher Correction: ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma. Nature Cancer. PMID 35149861 DOI: 10.1038/s43018-022-00343-8  0.709
2022 Javier R, Wang W, Drumm M, McCortney K, Sarkaria JN, Horbinski C. The efficacy of an unrestricted cycling ketogenic diet in preclinical models of IDH wild-type and IDH mutant glioma. Plos One. 17: e0257725. PMID 35134075 DOI: 10.1371/journal.pone.0257725  0.723
2022 Drumm M, Templer JW, Tate M, Jennings L, Horbinski C. Markedly prolonged disease course, with breakthrough seizures, in a glioma with an isolated IDH1 mutation. Neuro-Oncology Advances. 4: vdac004. PMID 35128400 DOI: 10.1093/noajnl/vdac004  0.69
2022 Pratt D, Abdullaev Z, Papanicolau-Sengos A, Ketchum C, Panneer Selvam P, Chung HJ, Lee I, Raffeld M, Gilbert MR, Armstrong TS, Pytel P, Borys E, Klonoski JM, McCord M, Horbinski C, et al. High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13. Acta Neuropathologica. PMID 35103816 DOI: 10.1007/s00401-022-02404-9  0.762
2021 Arrieta VA, Chen AX, Kane JR, Kang SJ, Kassab C, Dmello C, Zhao J, Burdett KB, Upadhyayula PS, Lee-Chang C, Shilati J, Jaishankar D, Chen L, Gould A, Zhang D, ... ... Horbinski C, et al. ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma. Nature Cancer. 2: 1372-1386. PMID 35121903 DOI: 10.1038/s43018-021-00260-2  0.737
2021 Sears TK, Horbinski CM, Woolard KD. IDH1 mutant glioma is preferentially sensitive to the HDAC inhibitor panobinostat. Journal of Neuro-Oncology. PMID 34424450 DOI: 10.1007/s11060-021-03829-0  0.741
2021 McCord M, Lukas RV, Amidei C, Demars N, Gelb A, Buck J, Sachdev S, Feldman A, Tate M, Dixit K, Brat DJ, Jennings L, Horbinski C. Disappearance of MMR-deficient subclones after controlled IL-12 and PD-1 inhibition in a glioma patient. Neuro-Oncology Advances. 3: vdab045. PMID 34250480 DOI: 10.1093/noajnl/vdab045  0.7
2020 Kanojia D, Panek WK, Cordero A, Fares J, Xiao A, Savchuk S, Kumar K, Xiao T, Pituch KC, Miska J, Zhang P, Kam KL, Horbinski C, Balyasnikova IV, Ahmed AU, et al. BET inhibition increases βIII-tubulin expression and sensitizes metastatic breast cancer in the brain to vinorelbine. Science Translational Medicine. 12. PMID 32848091 DOI: 10.1126/Scitranslmed.Aax2879  0.304
2020 Torre M, Vasudevaraja V, Serrano J, DeLorenzo M, Malinowski S, Blandin AF, Pages M, Ligon AH, Dong F, Meredith DM, Nasrallah MP, Horbinski C, Dahiya S, Ligon KL, Santi M, et al. Molecular and clinicopathologic features of gliomas harboring NTRK fusions. Acta Neuropathologica Communications. 8: 107. PMID 32665022 DOI: 10.1186/S40478-020-00980-Z  0.349
2020 Unruh D, Horbinski C. Beyond thrombosis: the impact of tissue factor signaling in cancer. Journal of Hematology & Oncology. 13: 93. PMID 32665005 DOI: 10.1186/S13045-020-00932-Z  0.303
2020 Nassiri F, Chakravarthy A, Feng S, Shen SY, Nejad R, Zuccato JA, Voisin MR, Patil V, Horbinski C, Aldape K, Zadeh G, De Carvalho DD. Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes. Nature Medicine. PMID 32572265 DOI: 10.1038/S41591-020-0932-2  0.346
2020 Cheng X, Geng F, Pan M, Wu X, Zhong Y, Wang C, Tian Z, Cheng C, Zhang R, Puduvalli V, Horbinski C, Mo X, Han X, Chakravarti A, Guo D. Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress. Cell Metabolism. PMID 32559414 DOI: 10.1016/J.Cmet.2020.06.002  0.309
2020 Ladomersky E, Zhai L, Lauing KL, Bell A, Xu J, Kocherginsky M, Zhang B, Wu JD, Podojil JR, Platanias LC, Mochizuki AY, Prins RM, Kumthekar P, Raizer J, Dixit K, ... ... Horbinski C, et al. Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32546647 DOI: 10.1158/1078-0432.Ccr-19-3874  0.339
2020 Kam KL, Appin CL, Mao Q, Ikegami S, Lukas RV, Nikiforova MN, Roy S, Brat DJ, Horbinski C. Is Next-Generation Sequencing Alone Sufficient to Reliably Diagnose Gliomas? Journal of Neuropathology and Experimental Neurology. PMID 32483596 DOI: 10.1093/Jnen/Nlaa044  0.37
2020 Feldman AZ, Jennings LJ, Wadhwani NR, Brat DJ, Horbinski CM. The Essentials of Molecular Testing in CNS Tumors: What to Order and How to Integrate Results. Current Neurology and Neuroscience Reports. 20: 23. PMID 32445025 DOI: 10.1007/S11910-020-01041-7  0.32
2020 Kane JR, Zhao J, Tsujiuchi T, Laffleur B, Arrieta VA, Mahajan A, Rao G, Mela A, Dmello C, Chen L, Zhang DY, Gonzalez-Buendia E, Lee-Chang C, Xiao T, Rothschild G, ... ... Horbinski C, et al. CD8 T-cell-mediated immunoediting influences genomic evolution and immune evasion in murine gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32430477 DOI: 10.1158/1078-0432.Ccr-19-3104  0.339
2020 Wen PY, Weller M, Lee EQ, Alexander BA, Barnholtz-Sloan JS, Barthel FP, Batchelor TT, Bindra RS, Chang SM, Chiocca EA, Cloughesy TF, DeGroot JF, Galanis E, Gilbert MR, Hegi ME, ... Horbinski C, et al. Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions. Neuro-Oncology. PMID 32328653 DOI: 10.1093/Neuonc/Noaa106  0.332
2020 Bayik D, Zhou Y, Park C, Hong C, Vail D, Silver DJ, Lauko A, Roversi G, Watson DC, Lo A, Alban TJ, McGraw M, Sorensen M, Grabowski MM, Otvos B, ... ... Horbinski C, et al. Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner. Cancer Discovery. PMID 32300059 DOI: 10.1158/2159-8290.Cd-19-1355  0.34
2020 Sastry NG, Wan X, Huang T, Alvarez AA, Pangeni RP, Song X, James CD, Horbinski CM, Brennan CW, Nakano I, Hu B, Cheng SY. LY6K Promotes Glioblastoma Tumorigenicity via CAV-1-Mediated ERK1/2 Signaling Enhancement. Neuro-Oncology. PMID 32055849 DOI: 10.1093/Neuonc/Noaa032  0.355
2020 McCord M, Steffens A, Javier R, Kam KL, McCortney K, Horbinski C. The efficacy of DNA mismatch repair enzyme immunohistochemistry as a screening test for hypermutated gliomas. Acta Neuropathologica Communications. 8: 15. PMID 32051040 DOI: 10.1186/S40478-020-0892-2  0.77
2020 Drumm MR, Dixit KS, Grimm S, Kumthekar P, Lukas RV, Raizer JJ, Stupp R, Chheda MG, Kam KL, McCord M, Sachdev S, Kruser T, Steffens A, Javier R, McCortney K, ... Horbinski C, et al. Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas. Neuro-Oncology. 22: 470-479. PMID 31711239 DOI: 10.1093/Neuonc/Noz216  0.762
2020 Cooley L, Kam K, Horbinski C, Sukhanova M, Gener M, Ginn K, Lu X. 7. ROS1-GOPC gene fusion characterizes a minor subset of brain tumors Cancer Genetics and Cytogenetics. 244: 3. DOI: 10.1016/J.Cancergen.2020.04.011  0.322
2019 Haider AS, van den Bent M, Wen PY, Vogelbaum MA, Chang S, Canoll PD, Horbinski CM, Huse JT. Towards a standard pathological and molecular characterization of recurrent glioma in adults: a RANO effort. Neuro-Oncology. PMID 31844891 DOI: 10.1093/Neuonc/Noz233  0.352
2019 Lukas RV, Wainwright DA, Horbinski CM, Iwamoto FM, Sonabend AM. Immunotherapy Against Gliomas: is the Breakthrough Near? Drugs. PMID 31598900 DOI: 10.1007/S40265-019-01203-Z  0.304
2019 Lee-Chang C, Rashidi A, Miska J, Zhang P, Pituch KC, Hou D, Xiao T, Fischietti M, Kang SJ, Appin CL, Horbinski C, Platanias LC, Lopez-Rosas A, Han Y, Balyasnikova IV, et al. Myeloid-derived suppressive cells promote B cell-mediated immunosuppression via transfer of PD-L1 in glioblastoma. Cancer Immunology Research. PMID 31530559 DOI: 10.1158/2326-6066.Cir-19-0240  0.321
2019 Song X, Wan X, Huang T, Zeng C, Sastry N, Wu B, James CD, Horbinski C, Nakano I, Zhang W, Hu B, Cheng SY. SRSF3-Regulated RNA Alternative Splicing Promotes Glioblastoma Tumorigenicity by Affecting Multiple Cellular Processes. Cancer Research. PMID 31462429 DOI: 10.1158/0008-5472.Can-19-1504  0.346
2019 Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sugiura Y, Sampetrean O, Ikeda Y, Warren M, Sakamoto N, Kitahara S, Yoshino H, Yamashita D, Sumita K, Wolfe K, Lange L, ... ... Horbinski C, et al. IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma. Nature Cell Biology. 21: 1003-1014. PMID 31371825 DOI: 10.1038/S41556-019-0363-9  0.322
2019 Roy S, Agnihotri S, El Hallani S, Ernst WL, Wald AI, Santana Dos Santos L, Hamilton RL, Horbinski CM, Wadhwani NR, Born DE, Pollack IF, Nikiforov YE, Nikiforova MN. Clinical Utility of GlioSeq Next-Generation Sequencing Test in Pediatric and Young Adult Patients With Brain Tumors. Journal of Neuropathology and Experimental Neurology. PMID 31298284 DOI: 10.1093/Jnen/Nlz055  0.559
2019 Horbinski C, Ligon KL, Brastianos P, Huse JT, Venere M, Chang S, Buckner J, Cloughesy T, Jenkins RB, Giannini C, Nabors LB, Wen PY, Aldape KJ, Lukas RV, Galanis E, et al. The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients. Neuro-Oncology. PMID 31276167 DOI: 10.1093/Neuonc/Noz119  0.359
2019 Unruh D, Zewde M, Buss A, Drumm MR, Tran AN, Scholtens DM, Horbinski C. Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers. Scientific Reports. 9: 8946. PMID 31222125 DOI: 10.1038/S41598-019-45346-1  0.739
2019 Chen H, Thomas C, Munoz FA, Alexandrescu S, Horbinski CM, Olar A, McGuone D, Camelo-Piragua S, Wang L, Pentsova E, Phillips J, Aldape K, Chen W, Iafrate AJ, Chi AS, et al. Polysomy is associated with poor outcome in 1p19q co-deleted oligodendroglial tumors. Neuro-Oncology. PMID 31140557 DOI: 10.1093/Neuonc/Noz098  0.35
2019 Qi J, Esfahani DR, Huang T, Ozark P, Bartom E, Hashizume R, Bonner ER, An S, Horbinski CM, James CD, Saratsis AM. Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease. Acta Neuropathologica Communications. 7: 75. PMID 31092287 DOI: 10.1186/S40478-019-0727-1  0.4
2019 Lamano JB, Quaggin-Smith JA, Horbinski CM, Tate MC, Grimm SA, Kumthekar PU, Bloch O. Long-term glioblastoma survival following recovery from cytomegalovirus colitis: A case report. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 30948314 DOI: 10.1016/J.Jocn.2019.03.051  0.374
2019 Hasan T, Caragher SP, Shireman JM, Park CH, Atashi F, Baisiwala S, Lee G, Guo D, Wang JY, Dey M, Wu M, Lesniak MS, Horbinski CM, James CD, Ahmed AU. Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma. Cell Death & Disease. 10: 292. PMID 30926789 DOI: 10.1038/S41419-019-1387-6  0.346
2019 Eckerdt F, Bell JB, Beauchamp EM, Clymer J, Blyth GT, Kosciuczuk EM, Ma Q, Chen DZ, Horbinski C, Goldman S, Munshi HG, Hashizume R, Platanias LC. Potent Antineoplastic Effects of Combined PI3Kα-MNK Inhibition in Medulloblastoma. Molecular Cancer Research : McR. PMID 30842251 DOI: 10.1158/1541-7786.Mcr-18-1193  0.387
2019 Lamano JB, Lamano JB, Li YD, DiDomenico JD, Choy W, Veliceasa D, Oyon DE, Fakurnejad S, Ampie L, Kesavabhotla K, Kaur R, Kaur G, Biyashev D, Unruh D, Horbinski C, et al. Glioblastoma-Derived IL-6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30824583 DOI: 10.1158/1078-0432.Ccr-18-2402  0.307
2019 Zhao J, Chen AX, Gartrell RD, Silverman AM, Aparicio L, Chu T, Bordbar D, Shan D, Samanamud J, Mahajan A, Filip I, Orenbuch R, Goetz M, Yamaguchi JT, Cloney M, ... Horbinski C, et al. Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma. Nature Medicine. PMID 30742119 DOI: 10.1038/S41591-019-0349-Y  0.361
2019 Suppiah S, Nassiri F, Bi WL, Dunn IF, Hanemann CO, Horbinski CM, Hashizume R, James CD, Mawrin C, Noushmehr H, Perry A, Sahm F, Sloan A, Von Deimling A, Wen PY, et al. Molecular and translational advances in meningiomas. Neuro-Oncology. 21: i4-i17. PMID 30649490 DOI: 10.1093/Neuonc/Noy178  0.339
2019 May JL, Kouri FM, Hurley LA, Liu J, Tommasini-Ghelfi S, Ji Y, Gao P, Calvert AE, Lee A, Chandel NS, Davuluri RV, Horbinski CM, Locasale JW, Stegh AH. IDH3α regulates one-carbon metabolism in glioblastoma. Science Advances. 5: eaat0456. PMID 30613765 DOI: 10.1126/Sciadv.Aat0456  0.31
2019 Tran A, Unruh D, Mirkov S, Horbinski C. Stem-06. Tissue Factor Signaling In Glioblastoma Tumor-Initiating Cells Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.980  0.315
2019 Robert Kane J, Zhao J, Tsujiuchi T, Laffleur B, Mahajan A, Rao G, Mela A, Dmello C, Arrieta VA, Chen L, Zhang DY, Lee-Chang C, Xiao T, Rothschild G, Basu U, ... Horbinski C, et al. IMMU-42. CD8+ T-CELLS MEDIATE IMMUNOEDITING, AND INFLUENCE GENOTYPE, TUMOR ONCOGENIC PATHWAYS AND MICROENVIRONMENT DURING PROGRESSION OF MURINE GLIOMAS Neuro-Oncology. 21: vi128-vi128. DOI: 10.1093/Neuonc/Noz175.534  0.343
2019 Wang Y, Horbinski C, James C, Sathiaseelan V, Kalapurakal J. TMOD-20. COMBINING TARGETED INHIBITOR AND RADIOTHERAPY IN TREATING ANAPLASTIC MENINGIOMA Neuro-Oncology. 21: vi266-vi267. DOI: 10.1093/Neuonc/Noz175.1119  0.356
2019 James C, Horbinski C, Bartom E, Burdett K, Scholtens D, Ahmed A. OS12.6 Intracranial GBM PDX Mutations Induced by Temozolomide Treatment Neuro-Oncology. 21: iii23-iii23. DOI: 10.1093/Neuonc/Noz126.078  0.377
2018 Huang T, Garcia R, Qi J, Lulla R, Horbinski C, Behdad A, Wadhwani N, Shilatifard A, James C, Saratsis A. Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and clinical outcomes. Oncotarget. 9: 37112-37124. PMID 30647848 DOI: 10.18632/Oncotarget.26430  0.352
2018 Jester R, Znoyko I, Garnovskaya M, Rozier JN, Kegl R, Patel S, Tran T, Abedalthagafi M, Horbinski CM, Richardson M, Wolff DJ, Lapadat R, Moore W, Rodriguez FJ, Mull J, et al. Expression of renal cell markers and detection of 3p loss links endolymphatic sac tumor to renal cell carcinoma and warrants careful evaluation to avoid diagnostic pitfalls. Acta Neuropathologica Communications. 6: 107. PMID 30340515 DOI: 10.1186/S40478-018-0607-0  0.329
2018 Unruh D, Mirkov S, Wray B, Drumm M, Lamano J, Li YD, Haider QF, Javier R, McCortney K, Saratsis AM, Scholtens DM, Sarkaria JN, James CD, Horbinski C. Methylation-dependent Tissue Factor suppression contributes to the reduced malignancy of IDH1 mutant gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30266764 DOI: 10.1158/1078-0432.Ccr-18-1222  0.738
2018 Koehler JW, Miller AD, Miller CR, Porter B, Aldape K, Beck J, Brat D, Cornax I, Corps K, Frank C, Giannini C, Horbinski C, Huse JT, O'Sullivan MG, Rissi DR, et al. A Revised Diagnostic Classification of Canine Glioma: Towards Validation of the Canine Glioma Patient as a Naturally Occurring Preclinical Model for Human Glioma. Journal of Neuropathology and Experimental Neurology. PMID 30239918 DOI: 10.1093/Jnen/Nly085  0.353
2018 Hussain F, Horbinski CM, Chmura SJ, Yamini B, Lukas RV. Response to BRAF/MEK Inhibition After Progression With BRAF Inhibition in a Patient With Anaplastic Pleomorphic Xanthoastrocytoma. The Neurologist. 23: 163-166. PMID 30169370 DOI: 10.1097/Nrl.0000000000000194  0.365
2018 Buerki RA, Horbinski CM, Kruser T, Horowitz PM, James CD, Lukas RV. An overview of meningiomas. Future Oncology (London, England). PMID 30084265 DOI: 10.2217/Fon-2018-0006  0.323
2018 Linninger A, Hartung GA, Liu BP, Mirkov S, Tangen K, Lukas RV, Unruh D, James CD, Sarkaria JN, Horbinski C. Modeling the diffusion of D-2-hydroxyglutarate from IDH1 mutant gliomas in the central nervous system. Neuro-Oncology. PMID 29660019 DOI: 10.1093/Neuonc/Noy051  0.322
2018 Aldape K, Amin SB, Ashley DM, Barnholtz-Sloan JS, Bates AJ, Beroukhim R, Bock C, Brat DJ, Claus EB, Costello JF, de Groot JF, Finocchiaro G, French PJ, Gan HK, Griffith B, ... ... Horbinski C, et al. Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium. Neuro-Oncology. PMID 29432615 DOI: 10.1093/Neuonc/Noy020  0.362
2018 Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, song x, shi T, Yongyong Y, Sastry N, Horbinski C, Lu S, Stupp R, Kessler J, Nishikawa R, Nakano I, et al. Abstract 1122: MST4 phosphorylation of ATG4B regulates autophagic activity, tumorigenicity, and radio resistance in glioblastoma Cancer Research. 78: 1122-1122. DOI: 10.1158/1538-7445.Am2018-1122  0.381
2017 Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, Lu S, Stupp R, Kessler JA, Nishikawa R, Nakano I, et al. MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma. Cancer Cell. 32: 840-855.e8. PMID 29232556 DOI: 10.1016/J.Ccell.2017.11.005  0.372
2017 Bell JB, Eckerdt F, Dhruv H, Finlay D, Peng S, Kim S, Kroczynska B, Beauchamp E, Alley K, Clymer J, Goldman S, Cheng SY, James CD, Nakano I, Horbinski C, et al. Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy is Regulated by MNK1 and mRNA Translation. Molecular Cancer Research : McR. PMID 29042487 DOI: 10.1158/1541-7786.Mcr-17-0397  0.355
2017 Zhai L, Ladomersky E, Lauing KL, Wu M, Genet M, Gritsina G, Győrffy B, Brastianos PK, Binder D, Sosman JA, Giles FJ, James CD, Horbinski C, Stupp R, Wainwright DA. Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28751450 DOI: 10.1158/1078-0432.Ccr-17-0120  0.338
2017 Panwalkar P, Clark J, Ramaswamy V, Hawes D, Yang F, Dunham C, Yip S, Hukin J, Sun Y, Schipper MJ, Chavez L, Margol A, Pekmezci M, Chung C, Banda A, ... ... Horbinski CM, et al. Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome. Acta Neuropathologica. PMID 28733933 DOI: 10.1007/S00401-017-1752-4  0.379
2017 Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, ... ... Horbinski CM, et al. Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. Nature. PMID 28678782 DOI: 10.1038/Nature23000  0.316
2017 Calvert AE, Chalastanis A, Wu Y, Hurley LA, Kouri FM, Bi Y, Kachman M, May JL, Bartom E, Hua Y, Mishra RK, Schiltz GE, Dubrovskyi O, Mazar AP, Peter ME, ... ... Horbinski C, et al. Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation. Cell Reports. 19: 1858-1873. PMID 28564604 DOI: 10.1016/J.Celrep.2017.05.014  0.386
2017 Huang TY, Piunti A, Lulla RR, Qi J, Horbinski CM, Tomita T, James CD, Shilatifard A, Saratsis AM. Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma. Acta Neuropathologica Communications. 5: 28. PMID 28416018 DOI: 10.1186/S40478-017-0436-6  0.376
2017 Chen H, Judkins J, Thomas C, Wu M, Khoury L, Benjamin CG, Pacione D, Golfinos JG, Kumthekar P, Ghamsari F, Chen L, Lein P, Chetkovich DM, Snuderl M, Horbinski C. Mutant IDH1 and seizures in patients with glioma. Neurology. PMID 28404805 DOI: 10.1212/Wnl.0000000000003911  0.552
2017 Wainwright DA, Horbinski CM, Hashizume R, James CD. Therapeutic Hypothesis Testing With Rodent Brain Tumor Models. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28321824 DOI: 10.1007/S13311-017-0523-1  0.353
2017 Huang B, Luo A, Durbin EB, Lycan E, Tucker T, Chen Q, Horbinski C, Villano JL. Incidence of CNS tumors in Appalachian children. Journal of Neuro-Oncology. PMID 28285334 DOI: 10.1007/S11060-017-2403-2  0.311
2017 Piunti A, Hashizume R, Morgan MA, Bartom ET, Horbinski CM, Marshall SA, Rendleman EJ, Ma Q, Takahashi YH, Woodfin AR, Misharin AV, Abshiru NA, Lulla RR, Saratsis AM, Kelleher NL, et al. Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas. Nature Medicine. PMID 28263307 DOI: 10.1038/Nm.4296  0.396
2017 Wicker CA, Scott TL, Suganya R, Arnold SM, Brill YM, Horbinski CM, Napier D, Valentino J, Kudrimoti MR, Yu G, Izumi T. Abstract 4142: Regulation of tumor suppressor decorin by APE1 in head and neck squamous cell carcinoma Cancer Research. 77: 4142-4142. DOI: 10.1158/1538-7445.Am2017-4142  0.362
2017 Unruh D, Mirkov S, James CD, Horbinski C. Abstract 1345: Mutant IDH1 and tissue factor in gliomas Cancer Research. 77: 1345-1345. DOI: 10.1158/1538-7445.Am2017-1345  0.39
2017 Oh S, Vigneswaran K, Schniederjan M, Horbinski C, Hambardzumyan D, Becher O, Kenney A, Read R. PDTM-35. THERAPEUTIC RELEVANCE OF YAP/TAZ ACTIVITY IN PEDIATRIC HIGH-GRADE GLIOMA. Neuro-Oncology. 19: vi197-vi197. DOI: 10.1093/Neuonc/Nox168.798  0.313
2017 Zhai L, Ladomersky E, Lauing K, Wu M, Genet M, Gritsina G, Gyorffy B, Brastianos P, Binder D, Sosman J, Giles F, James CD, Horbinski CM, Stupp R, Wainwright D. IMMU-66. IDO1 EXPRESSION STRATIFIES PATIENT SURVIVAL AND IS REGULATED BY TUMOR INFILTRATING T CELLS IN HUMAN GLIOBLASTOMA Neuro-Oncology. 19: vi127-vi127. DOI: 10.1093/Neuonc/Nox168.523  0.351
2017 James CD, Stupp R, Lukas RV, Kalapurakal JA, Akhtar-Zaidi B, Horbinski CM. TMOD-17. BRAIN TUMOR PATIENT DERIVED XENOGRAFT FROM LUNG TUMOR METASTASIS: ESTABLISHMENT AND CHARACTERIZATION Neuro-Oncology. 19: vi258-vi258. DOI: 10.1093/Neuonc/Nox168.1055  0.341
2017 Ahmed AU, Horbinski CM, Stupp R, Lesniak MS, James CD. P08.01 Tumor cell subpopulation changes during intracranial glioblastoma patient derived xenograft recurrence following radiation, temozolomide, or combination therapy Neuro-Oncology. 19: iii53-iii53. DOI: 10.1093/Neuonc/Nox036.191  0.357
2017 Chen H, Judkins J, Ghamsari F, Lein P, Horbinski C. OS05.1 The D-2-hydroxyglutarate product of mutant IDH1 induces synchronized neuronal firing via NMDA receptor activation Neuro-Oncology. 19: iii8-iii9. DOI: 10.1093/Neuonc/Nox036.028  0.493
2016 Unruh D, Schwarze SR, Khoury L, Thomas C, Wu M, Chen L, Chen R, Liu Y, Schwartz MA, Amidei C, Kumthekar P, Benjamin CG, Song K, Dawson C, Rispoli JM, ... ... Horbinski C, et al. Mutant IDH1 and thrombosis in gliomas. Acta Neuropathologica. PMID 27664011 DOI: 10.1007/S00401-016-1620-7  0.38
2016 Chang AL, Miska J, Wainwright DA, Dey M, Rivetta CV, Yu D, Kanojia D, Pituch KC, Qiao J, Pytel P, Han Y, Wu M, Zhang L, Horbinski C, Ahmed AU, et al. CCL2 produced by the glioma microenvironment is essential for the recruitment of regulatory T cells and myeloid-derived suppressor cells. Cancer Research. PMID 27530322 DOI: 10.1158/0008-5472.Can-16-0144  0.366
2016 Hashizume R, Zhang A, Mueller S, Prados MD, Lulla RR, Goldman S, Saratsis AM, Mazar AP, Stegh AH, Cheng SY, Horbinski C, Haas-Kogan DA, Sarkaria JN, Waldman T, James CD. Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth. Neuro-Oncology. PMID 27370397 DOI: 10.1093/Neuonc/Now106  0.367
2016 Bell JB, Eckerdt F, Alley K, Magnusson LP, Hussain H, Bi Y, Arslan AD, Clymer J, Alvarez AA, Goldman S, Cheng SY, Nakano I, Horbinski C, Davuluri RV, James CD, et al. MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma. Molecular Cancer Research : McR. PMID 27364770 DOI: 10.1158/1541-7786.Mcr-16-0172  0.402
2016 Scott TL, Wicker CA, Suganya R, Dhar B, Pittman T, Horbinski C, Izumi T. Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin. Molecular Carcinogenesis. PMID 27148961 DOI: 10.1002/Mc.22495  0.306
2016 Zhai L, Genet M, Ladomersky E, Lauing K, Wu M, Binder D, Kim L, Rich J, Horbinski C, James CD, Sosman JA, Bloch O, Wainwright DA. Abstract A064: IDO1 expression stratifies glioblastoma patient survival and correlates with dominantly immunosuppressive pathways Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A064  0.313
2016 Zhou P, Erfani S, Segal R, Horbinski C, Yang XH. Abstract 5092: CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion Cancer Research. 76: 5092-5092. DOI: 10.1158/1538-7445.Am2016-5092  0.369
2016 Chen H, Judkins J, Ghamsari F, Lein P, Horbinski C. QLIF-03. MUTANT IDH1 PROMOTES TUMOR-ASSOCIATED EPILEPSY IN GLIOMA PATIENTS Neuro-Oncology. 18: vi156-vi156. DOI: 10.1093/Neuonc/Now212.649  0.584
2016 Chen H, Thomas C, Munoz FA, Alexandrescu S, Horbinski C, Olar A, McGuone D, Camelo-Piragua S, Wang L, Pentsova E, Phillips J, Aldape K, Iafrate AJ, Golfinos J, Chi A, et al. MPTH-34. THE PROGNOSTIC VALUE OF POLYSOMY IN OLIGODENDROGLIAL TUMORS Neuro-Oncology. 18: vi113-vi113. DOI: 10.1093/Neuonc/Now212.471  0.326
2015 Nikiforova MN, Wald AI, Melan MA, Roy S, Zhong S, Hamilton RL, Lieberman FS, Drappatz J, Amankulor NM, Pollack IF, Nikiforov YE, Horbinski C. Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors. Neuro-Oncology. PMID 26681766 DOI: 10.1093/Neuonc/Nov289  0.54
2015 Zhou P, Erfani S, Liu Z, Jia C, Chen Y, Xu B, Deng X, Alfaro JE, Chen L, Napier D, Lu M, Huang JA, Liu C, Thibault O, Segal R, ... ... Horbinski C, et al. CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion. Oncotarget. PMID 26377974 DOI: 10.18632/Oncotarget.4896  0.384
2015 Venere M, Horbinski C, Crish JF, Jin X, Vasanji A, Major J, Burrows AC, Chang C, Prokop J, Wu Q, Sims PA, Canoll P, Summers MK, Rosenfeld SS, Rich JN. The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma. Science Translational Medicine. 7: 304ra143. PMID 26355032 DOI: 10.1126/Scitranslmed.Aac6762  0.357
2015 Lee DH, Zhang Y, Kassam AB, Park MJ, Gardner P, Prevedello D, Henry S, Horbinski C, Beumer JH, Tawbi H, Williams BJ, Shaffrey ME, Egorin MJ, Abounader R, Park DM. Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma. Plos One. 10: e0134426. PMID 26247786 DOI: 10.1371/Journal.Pone.0134426  0.359
2015 Lee TJ, Haque F, Shu D, Yoo JY, Li H, Yokel RA, Horbinski C, Kim TH, Kim SH, Kwon CH, Nakano I, Kaur B, Guo P, Croce CM. RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model. Oncotarget. 6: 14766-76. PMID 25885522 DOI: 10.18632/Oncotarget.3632  0.315
2015 Xie Q, Wu Q, Horbinski CM, Flavahan WA, Yang K, Zhou W, Dombrowski SM, Huang Z, Fang X, Shi Y, Ferguson AN, Kashatus DF, Bao S, Rich JN. Mitochondrial control by DRP1 in brain tumor initiating cells. Nature Neuroscience. 18: 501-10. PMID 25730670 DOI: 10.1038/Nn.3960  0.333
2015 Massarweh SA, Chmielecki J, Sun J, Stewart RL, Dressler EVM, Kadamyan V, Chambers MD, Horbinski C, Mehdi M, Black EP, Romond EH. Effect of mutations in distinct components of the PI3K/AKT/mTOR pathway on sensitivity to endocrine therapy in estrogen receptor (ER)-positive breast cancer. Journal of Clinical Oncology. 33: 532-532. DOI: 10.1200/Jco.2015.33.15_Suppl.532  0.352
2015 Schwarze S, Khoury L, Thomas C, Benjamin C, Chen R, Chen L, Liu Y, Song K, Dawson C, Pacione D, Zagzag D, McIntyre T, Snuderl M, Horbinski C. TMIC-13MUTANTIDH1/2SUPPRESSES LOCAL AND SYSTEMIC THROMBOSIS IN GLIOMA PATIENTS Neuro-Oncology. 17: v217.5-v217. DOI: 10.1093/Neuonc/Nov236.13  0.375
2014 Liu Y, Gilbert MR, Kyprianou N, Rangnekar VM, Horbinski C. The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells. Acta Neuropathologica. 128: 723-32. PMID 25135281 DOI: 10.1007/S00401-014-1334-7  0.41
2014 Thakkar JP, Dolecek TA, Horbinski C, Ostrom QT, Lightner DD, Barnholtz-Sloan JS, Villano JL. Epidemiologic and molecular prognostic review of glioblastoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 23: 1985-96. PMID 25053711 DOI: 10.1158/1055-9965.Epi-14-0275  0.353
2014 Chen L, Voronovich Z, Clark K, Hands I, Mannas J, Walsh M, Nikiforova MN, Durbin EB, Weiss H, Horbinski C. Predicting the likelihood of an isocitrate dehydrogenase 1 or 2 mutation in diagnoses of infiltrative glioma. Neuro-Oncology. 16: 1478-83. PMID 24860178 DOI: 10.1093/Neuonc/Nou097  0.31
2014 Hale JS, Otvos B, Sinyuk M, Alvarado AG, Hitomi M, Stoltz K, Wu Q, Flavahan W, Levison B, Johansen ML, Schmitt D, Neltner JM, Huang P, Ren B, Sloan AE, ... ... Horbinski C, et al. Cancer stem cell-specific scavenger receptor 36 drives glioblastoma progression. Stem Cells (Dayton, Ohio). 32: 1746-58. PMID 24737733 DOI: 10.1002/Stem.1716  0.629
2014 Gilbert MR, Liu Y, Neltner J, Pu H, Morris A, Sunkara M, Pittman T, Kyprianou N, Horbinski C. Autophagy and oxidative stress in gliomas with IDH1 mutations. Acta Neuropathologica. 127: 221-33. PMID 24150401 DOI: 10.1007/S00401-013-1194-6  0.357
2014 Venere M, Crish J, Wu Q, Horbinski C, Rich J, Rosenfeld S. SC-32 * TARGETING PROLIFERATION AND INVASION IN GLIOBLASTOMA VIA MITOTIC KINESINS Neuro-Oncology. 16: v203-v204. DOI: 10.1093/Neuonc/Nou275.31  0.388
2014 Lathia JD, Hale JS, Sloan AE, Gladson CL, Hazen SL, Horbinski C, Rich JN, Brown JM. INTEGRATION OF CANCER STEM CELL MAINTENANCE AND LIPID METABOLISM BY SCAVENGER RECEPTORS Neuro-Oncology. 16: iii17-iii17. DOI: 10.1093/Neuonc/Nou206.62  0.311
2014 Horbinski C, Liu Y, Gilbert MR, Kyprianou N. MUTANT IDH1 SUPPRESSES APOPTOSIS REGULATOR PAR-4 IN GLIOMAS Neuro-Oncology. 16: iii6-iii6. DOI: 10.1093/Neuonc/Nou206.21  0.4
2013 Horbinski C. What do we know about IDH1/2 mutations so far, and how do we use it? Acta Neuropathologica. 125: 621-36. PMID 23512379 DOI: 10.1007/S00401-013-1106-9  0.306
2013 Phillips JJ, Aranda D, Ellison DW, Judkins AR, Croul SE, Brat DJ, Ligon KL, Horbinski C, Venneti S, Zadeh G, Santi M, Zhou S, Appin CL, Sioletic S, Sullivan LM, et al. PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma. Brain Pathology (Zurich, Switzerland). 23: 565-73. PMID 23438035 DOI: 10.1111/Bpa.12043  0.356
2013 Clark KH, Villano JL, Nikiforova MN, Hamilton RL, Horbinski C. 1p/19q testing has no significance in the workup of glioblastomas. Neuropathology and Applied Neurobiology. 39: 706-17. PMID 23363074 DOI: 10.1111/Nan.12031  0.481
2013 Horbinski C. To BRAF or not to BRAF: is that even a question anymore? Journal of Neuropathology and Experimental Neurology. 72: 2-7. PMID 23242278 DOI: 10.1097/Nen.0B013E318279F3Db  0.346
2012 Horbinski C. Something old and something new about molecular diagnostics in gliomas. Surgical Pathology Clinics. 5: 919-939. PMID 23459421 DOI: 10.1016/J.Path.2012.09.001  0.31
2012 Horbinski C, Nikiforova MN, Hagenkord JM, Hamilton RL, Pollack IF. Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas. Neuro-Oncology. 14: 777-89. PMID 22492957 DOI: 10.1093/Neuonc/Nos077  0.545
2012 Hobbs J, Nikiforova MN, Fardo DW, Bortoluzzi S, Cieply K, Hamilton RL, Horbinski C. Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas. The American Journal of Surgical Pathology. 36: 1186-93. PMID 22472960 DOI: 10.1097/Pas.0B013E3182518E12  0.533
2012 Horbinski C, Nikiforova MN, Hobbs J, Bortoluzzi S, Cieply K, Dacic S, Hamilton RL. The importance of 10q status in an outcomes-based comparison between 1p/19q fluorescence in situ hybridization and polymerase chain reaction-based microsatellite loss of heterozygosity analysis of oligodendrogliomas. Journal of Neuropathology and Experimental Neurology. 71: 73-82. PMID 22157622 DOI: 10.1097/Nen.0B013E318240Fa65  0.476
2012 Liu Y, Komohara Y, Domenick N, Ohno M, Ikeura M, Hamilton RL, Horbinski C, Wang X, Ferrone S, Okada H. Expression of antigen processing and presenting molecules in brain metastasis of breast cancer. Cancer Immunology, Immunotherapy : Cii. 61: 789-801. PMID 22065046 DOI: 10.1007/S00262-011-1137-9  0.502
2012 Horbinski C, Nikiforova MN, Hagenkord J, Hamilton RL, Pollack IF. Abstract 5558: Interplay between BRAF, p16, p53, and MIB1 in pediatric low grade gliomas Cancer Research. 72: 5558-5558. DOI: 10.1158/1538-7445.Am2012-5558  0.541
2012 Gilbert M, Liu Y, Morris A, Sunkara M, Kyprinaou N, Horbinski C. Abstract 4971: The oncometabolite (R)-2-hydroxyglutarate modulates stress-induced caspase activity in glioma cells Cancer Research. 72: 4971-4971. DOI: 10.1158/1538-7445.Am2012-4971  0.35
2011 Horbinski C, Hobbs J, Cieply K, Dacic S, Hamilton RL. EGFR expression stratifies oligodendroglioma behavior. The American Journal of Pathology. 179: 1638-44. PMID 21839716 DOI: 10.1016/J.Ajpath.2011.06.020  0.522
2011 Horbinski C, Kofler J, Yeaney G, Camelo-Piragua S, Venneti S, Louis DN, Perry A, Murdoch G, Nikiforova M. Isocitrate dehydrogenase 1 analysis differentiates gangliogliomas from infiltrative gliomas. Brain Pathology (Zurich, Switzerland). 21: 564-74. PMID 21314850 DOI: 10.1111/J.1750-3639.2011.00480.X  0.75
2011 Horbinski C, Miller CR, Perry A. Gone FISHing: clinical lessons learned in brain tumor molecular diagnostics over the last decade. Brain Pathology (Zurich, Switzerland). 21: 57-73. PMID 21129060 DOI: 10.1111/J.1750-3639.2010.00453.X  0.322
2011 Horbinski C, Dillon D, Pittman T. Low-grade recurrence of a congenital high-grade supratentorial tumor with astrocytic features in the absence of adjuvant therapy. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 31: 286-91. PMID 20880322 DOI: 10.1111/J.1440-1789.2010.01156.X  0.386
2011 Liu Y, Komohara Y, Domenick N, Horbinski C, Hamilton R, Ferrone S, Okada H. Abstract 2439: Association of antigen processing machinery components and CD8+ T-cell infiltration in breast cancer brain metastasis Cancer Research. 71: 2439-2439. DOI: 10.1158/1538-7445.Am2011-2439  0.486
2010 Horbinski C. Practical molecular diagnostics in neuropathology: making a tough job a little easier. Seminars in Diagnostic Pathology. 27: 105-13. PMID 20860314 DOI: 10.1053/J.Semdp.2010.04.001  0.373
2010 Horbinski C, Mojesky C, Kyprianou N. Live free or die: tales of homeless (cells) in cancer. The American Journal of Pathology. 177: 1044-52. PMID 20639456 DOI: 10.2353/Ajpath.2010.091270  0.349
2010 Horbinski C, Pollack IF, Wiley C, Murdoch G. A 10-year old girl with neck pain. Brain Pathology (Zurich, Switzerland). 20: 519-22. PMID 20438474 DOI: 10.1111/j.1750-3639.2009.00365.x  0.416
2010 Horbinski C, Kelly L, Nikiforov YE, Durso MB, Nikiforova MN. Detection of IDH1 and IDH2 mutations by fluorescence melting curve analysis as a diagnostic tool for brain biopsies. The Journal of Molecular Diagnostics : Jmd. 12: 487-92. PMID 20431032 DOI: 10.2353/Jmoldx.2010.090228  0.354
2010 Horbinski C, Wang G, Wiley CA. YKL-40 is directly produced by tumor cells and is inversely linked to EGFR in glioblastomas. International Journal of Clinical and Experimental Pathology. 3: 226-37. PMID 20224722  0.508
2010 Horbinski C, Hamilton RL, Nikiforov Y, Pollack IF. Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas. Acta Neuropathologica. 119: 641-9. PMID 20044755 DOI: 10.1007/S00401-009-0634-9  0.538
2010 Horbinski C, Hamilton RL, Lovell C, Burnham J, Pollack IF. Impact of morphology, MIB-1, p53 and MGMT on outcome in pilocytic astrocytomas. Brain Pathology (Zurich, Switzerland). 20: 581-8. PMID 19832838 DOI: 10.1111/J.1750-3639.2009.00336.X  0.536
2009 Horbinski C, Mintz A, Engh J, Lieberman F, Hamilton RL, Park DM. Post-therapeutic changes in the molecular profile of glioblastomas. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 2026. PMID 27964598 DOI: 10.1200/Jco.2009.27.15_Suppl.2026  0.531
2009 Park DM, Prevedello DM, Gardner P, Lee D, Henry S, Snyderman C, Carrau R, Horbinski C, Hamilton RL, Kassam AB. Clival chordoma molecular subtypes and clinical behavior. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 10538. PMID 27963890 DOI: 10.1200/Jco.2009.27.15_Suppl.10538  0.481
2009 Horbinski C, Kofler J, Kelly LM, Murdoch GH, Nikiforova MN. Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues. Journal of Neuropathology and Experimental Neurology. 68: 1319-25. PMID 19915484 DOI: 10.1097/Nen.0B013E3181C391Be  0.523
2009 Horbinski C, Wiley CA. Comparison of telepathology systems in neuropathological intraoperative consultations. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 29: 655-63. PMID 19422534 DOI: 10.1111/J.1440-1789.2009.01022.X  0.494
2009 Horbinski C, Hamilton RL. Application of telepathology for neuropathologic intraoperative consultations. Brain Pathology (Zurich, Switzerland). 19: 317-22. PMID 19290998 DOI: 10.1111/J.1750-3639.2009.00265.X  0.456
2009 Horbinski C, Bartynski WS, Carson-Walter E, Hamilton RL, Tan HP, Cheng S. Reversible encephalopathy after cardiac transplantation: histologic evidence of endothelial activation, T-cell specific trafficking, and vascular endothelial growth factor expression. Ajnr. American Journal of Neuroradiology. 30: 588-90. PMID 18854444 DOI: 10.3174/Ajnr.A1311  0.473
2009 Horbinski C, Dacic S, McLendon RE, Cieply K, Datto M, Brat DJ, Chu CT. Chordoid glioma: a case report and molecular characterization of five cases. Brain Pathology (Zurich, Switzerland). 19: 439-48. PMID 18652591 DOI: 10.1111/J.1750-3639.2008.00196.X  0.66
2008 Horbinski C, Cieply K, Bejjani GK, McFadden K. Primary intracranial dural-based synovial sarcoma with an unusual SYT fluorescence in situ hybridization pattern. Journal of Neurosurgery. 109: 897-903. PMID 18976081 DOI: 10.3171/Jns/2008/109/11/0897  0.664
2008 Striebel JM, Bhargava R, Horbinski C, Surti U, Dabbs DJ. The equivocally amplified HER2 FISH result on breast core biopsy: indications for further sampling do affect patient management. American Journal of Clinical Pathology. 129: 383-90. PMID 18285260 DOI: 10.1309/Kfkdnk8Cenvn24Vu  0.334
2007 Horbinski C, Fine JL, Medina-Flores R, Yagi Y, Wiley CA. Telepathology for intraoperative neuropathologic consultations at an academic medical center: a 5-year report. Journal of Neuropathology and Experimental Neurology. 66: 750-9. PMID 17882019 DOI: 10.1097/Nen.0B013E318126C179  0.748
2007 Kulich SM, Horbinski C, Patel M, Chu CT. 6-Hydroxydopamine induces mitochondrial ERK activation. Free Radical Biology & Medicine. 43: 372-83. PMID 17602953 DOI: 10.1016/J.Freeradbiomed.2007.04.028  0.733
2007 Zhu JH, Horbinski C, Guo F, Watkins S, Uchiyama Y, Chu CT. Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. The American Journal of Pathology. 170: 75-86. PMID 17200184 DOI: 10.2353/Ajpath.2007.060524  0.751
2007 Horbinski C, Wiley C. Molecular Genetic Analysis of Oligodendroglial Tumors Yearbook of Pathology and Laboratory Medicine. 2007: 233-235. DOI: 10.1016/S1077-9108(08)70402-X  0.532
2005 Horbinski C, Chu CT. Kinase signaling cascades in the mitochondrion: a matter of life or death. Free Radical Biology & Medicine. 38: 2-11. PMID 15589366 DOI: 10.1016/J.Freeradbiomed.2004.09.030  0.532
2004 Kim WY, Horbinski C, Sigurdson W, Higgins D. Proteasome inhibitors suppress formation of polyglutamine-induced nuclear inclusions in cultured postmitotic neurons. Journal of Neurochemistry. 91: 1044-56. PMID 15569248 DOI: 10.1111/J.1471-4159.2004.02788.X  0.59
2003 Garrick MD, Dolan KG, Horbinski C, Ghio AJ, Higgins D, Porubcin M, Moore EG, Hainsworth LN, Umbreit JN, Conrad ME, Feng L, Lis A, Roth JA, Singleton S, Garrick LM. DMT1: a mammalian transporter for multiple metals. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 16: 41-54. PMID 12572663 DOI: 10.1023/A:1020702213099  0.382
2002 Roth JA, Horbinski C, Higgins D, Lein P, Garrick MD. Mechanisms of manganese-induced rat pheochromocytoma (PC12) cell death and cell differentiation. Neurotoxicology. 23: 147-57. PMID 12224755 DOI: 10.1016/S0161-813X(01)00077-8  0.582
2002 Horbinski C, Stachowiak EK, Chandrasekaran V, Miuzukoshi E, Higgins D, Stachowiak MK. Bone morphogenetic protein-7 stimulates initial dendritic growth in sympathetic neurons through an intracellular fibroblast growth factor signaling pathway. Journal of Neurochemistry. 80: 54-63. PMID 11796743 DOI: 10.1046/J.0022-3042.2001.00657.X  0.418
2001 Dattatreyamurty B, Roux E, Horbinski C, Kaplan PL, Robak LA, Beck HN, Lein P, Higgins D, Chandrasekaran V. Cerebrospinal fluid contains biologically active bone morphogenetic protein-7. Experimental Neurology. 172: 273-81. PMID 11716552 DOI: 10.1006/Exnr.2001.7728  0.568
2001 Guo X, Lin Y, Horbinski C, Drahushuk KM, Kim IJ, Kaplan PL, Lein P, Wang T, Higgins D. Dendritic growth induced by BMP-7 requires Smad1 and proteasome activity. Journal of Neurobiology. 48: 120-30. PMID 11438941 DOI: 10.1002/Neu.1046  0.738
2001 Horbinski C, Stachowiak MK, Higgins D, Finnegan SG. Polyethyleneimine-mediated transfection of cultured postmitotic neurons from rat sympathetic ganglia and adult human retina. Bmc Neuroscience. 2: 2. PMID 11231879 DOI: 10.1186/1471-2202-2-2  0.392
2000 Roth JA, Horbinski C, Feng L, Dolan KG, Higgins D, Garrick MD. Differential localization of divalent metal transporter 1 with and without iron response element in rat PC12 and sympathetic neuronal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7595-601. PMID 11027219 DOI: 10.1523/Jneurosci.20-20-07595.2000  0.394
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