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Phyllis L. Faust, MD PhD - Publications

Affiliations: 
Pathology Columbia University, New York, NY 
Area:
We are studying a PEX2 mouse model for the human neuronal migration disorder Zellweger syndrome. The defective assembly of the peroxisomal organelle in this disease leads to widespread metabolic disarray in selected cellular lipid pathways and results in
Website:
http://156.111.235.11/pharm/cumc/profile.php?id=20

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yang Y, Zheng C, Chen B, Hernandez NC, Faust PL, Cai Z, Louis ED, Matuskey D. Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density. Cerebellum (London, England). PMID 37783917 DOI: 10.1007/s12311-023-01611-8  0.323
2023 Yang Y, Zheng C, Chen B, Hernandez NC, Faust PL, Cai Z, Louis ED, Matuskey D. Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density. Research Square. PMID 37205584 DOI: 10.21203/rs.3.rs-2838184/v1  0.346
2023 Louis ED, Martuscello RT, Gionco JT, Hartstone WG, Musacchio JB, Portenti M, McCreary M, Kuo SH, Vonsattel JG, Faust PL. Histopathology of the cerebellar cortex in essential tremor and other neurodegenerative motor disorders: comparative analysis of 320 brains. Acta Neuropathologica. PMID 36607423 DOI: 10.1007/s00401-022-02535-z  0.782
2022 Martuscello RT, Sivaprakasam K, Hartstone W, Kuo SH, Konopka G, Louis ED, Faust PL. Gene Expression Analysis of Laser-Captured Purkinje Cells in the Essential Tremor Cerebellum. Cerebellum (London, England). PMID 36242761 DOI: 10.1007/s12311-022-01483-4  0.354
2022 Louis ED, Iglesias-Hernandez D, Hernandez NC, Flowers X, Kuo SH, Vonsattel JPG, Faust PL. Characterizing Lewy Pathology in 231 Essential Tremor Brains From the Essential Tremor Centralized Brain Repository. Journal of Neuropathology and Experimental Neurology. PMID 35950950 DOI: 10.1093/jnen/nlac068  0.305
2022 Faust PL. Is essential tremor a degenerative disorder or an electric disorder? Degenerative disorder. International Review of Neurobiology. 163: 65-101. PMID 35750370 DOI: 10.1016/bs.irn.2022.02.003  0.365
2021 Kim SH, Farrell K, Cosentino S, Vonsattel JG, Faust PL, Cortes EP, Bennet DA, Louis ED, Crary JF. Tau Isoform Profile in Essential Tremor Diverges From Other Tauopathies. Journal of Neuropathology and Experimental Neurology. PMID 34363663 DOI: 10.1093/jnen/nlab073  0.747
2021 Gionco JT, Hartstone WG, Martuscello RT, Kuo SH, Faust PL, Louis ED. Essential Tremor versus "ET-plus": A Detailed Postmortem Study of Cerebellar Pathology. Cerebellum (London, England). PMID 33768479 DOI: 10.1007/s12311-021-01263-6  0.437
2020 Louis ED, Faust PL. Essential Tremor Within the Broader Context of Other Forms of Cerebellar Degeneration. Cerebellum (London, England). PMID 32666285 DOI: 10.1007/s12311-020-01160-4  0.399
2020 Louis ED, Faust PL. Essential tremor pathology: neurodegeneration and reorganization of neuronal connections. Nature Reviews. Neurology. PMID 31959938 DOI: 10.1038/S41582-019-0302-1  0.435
2020 Pan MK, Li YS, Wong SB, Ni CL, Wang YM, Liu WC, Lu LY, Lee JC, Cortes EP, Vonsattel JG, Sun Q, Louis ED, Faust PL, Kuo SH. Cerebellar oscillations driven by synaptic pruning deficits of cerebellar climbing fibers contribute to tremor pathophysiology. Science Translational Medicine. 12. PMID 31941824 DOI: 10.1126/Scitranslmed.Aay1769  0.769
2019 Martuscello RT, Kerridge CA, Chatterjee D, Hartstone WG, Kuo SH, Sims PA, Louis ED, Faust PL. Gene Expression Analysis of the Cerebellar Cortex in Essential Tremor. Neuroscience Letters. 134540. PMID 31707044 DOI: 10.1016/J.Neulet.2019.134540  0.473
2019 Louis ED, Kerridge CA, Chatterjee D, Martuscello RT, Diaz DT, Koeppen AH, Kuo SH, Vonsattel JG, Sims PA, Faust PL. Contextualizing the pathology in the essential tremor cerebellar cortex: a patholog-omics approach. Acta Neuropathologica. PMID 31317229 DOI: 10.1007/S00401-019-02043-7  0.785
2018 Lee PJ, Kerridge CA, Chatterjee D, Koeppen AH, Faust PL, Louis ED. A Quantitative Study of Empty Baskets in Essential Tremor and Other Motor Neurodegenerative Diseases. Journal of Neuropathology and Experimental Neurology. PMID 30590599 DOI: 10.1093/Jnen/Nly114  0.513
2018 Farrell K, Cosentino S, Iida MA, Chapman S, Bennett DA, Faust PL, Louis ED, Crary JF. Quantitative Assessment of Pathological Tau Burden in Essential Tremor: A Postmortem Study. Journal of Neuropathology and Experimental Neurology. PMID 30476290 DOI: 10.1093/Jnen/Nly104  0.399
2018 Lee D, Gan SR, Faust PL, Louis ED, Kuo SH. Climbing fiber-Purkinje cell synaptic pathology across essential tremor subtypes. Parkinsonism & Related Disorders. PMID 29482925 DOI: 10.1016/J.Parkreldis.2018.02.032  0.463
2017 Louis ED, Kuo SH, Tate WJ, Kelly GC, Faust PL. Cerebellar Pathology in Childhood-Onset vs. Adult-Onset Essential Tremor. Neuroscience Letters. PMID 28867587 DOI: 10.1016/J.Neulet.2017.08.072  0.458
2017 Louis ED, Kuo SH, Tate WJ, Kelly GC, Gutierrez J, Cortes EP, Vonsattel JG, Faust PL. Heterotopic Purkinje Cells: a Comparative Postmortem Study of Essential Tremor and Spinocerebellar Ataxias 1, 2, 3, and 6. Cerebellum (London, England). PMID 28791574 DOI: 10.1007/S12311-017-0876-3  0.784
2017 Louis ED, Kuo SH, Wang J, Tate WJ, Pan MK, Kelly GC, Gutierrez J, Cortes EP, Vonsattel JG, Faust PL. Cerebellar Pathology in Familial vs. Sporadic Essential Tremor. Cerebellum (London, England). PMID 28364185 DOI: 10.1007/S12311-017-0853-X  0.777
2016 Kuo SH, Wang J, Tate WJ, Pan MK, Kelly GC, Gutierrez J, Cortes EP, Vonsattel JG, Louis ED, Faust PL. Cerebellar Pathology in Early Onset and Late Onset Essential Tremor. Cerebellum (London, England). PMID 27726094 DOI: 10.1007/S12311-016-0826-5  0.768
2016 Kuo SH, Lin CY, Wang J, Sims PA, Pan MK, Liou JY, Lee D, Tate WJ, Kelly GC, Louis ED, Faust PL. Climbing fiber-Purkinje cell synaptic pathology in tremor and cerebellar degenerative diseases. Acta Neuropathologica. PMID 27704282 DOI: 10.1007/S00401-016-1626-1  0.441
2016 Wang J, Kelly GC, Tate WJ, Li YS, Lee M, Gutierrez J, Louis ED, Faust PL, Kuo SH. Excitatory Amino acid transporter expression in the essential tremor dentate nucleus and cerebellar cortex: A postmortem study. Parkinsonism & Related Disorders. PMID 27624392 DOI: 10.1016/J.Parkreldis.2016.09.003  0.333
2016 Kuo SH, Lin CY, Wang J, Liou JY, Pan MK, Louis RJ, Wu WP, Gutierrez J, Louis ED, Faust PL. Deep Brain Stimulation and Climbing Fiber Synaptic Pathology in Essential Tremor. Annals of Neurology. PMID 27422481 DOI: 10.1002/Ana.24728  0.421
2016 Barca E, Kleiner G, Tang G, Ziosi M, Tadesse S, Masliah E, Louis ED, Faust P, Kang UJ, Torres J, Cortes EP, Vonsattel JG, Kuo SH, Quinzii CM. Decreased Coenzyme Q10 Levels in Multiple System Atrophy Cerebellum. Journal of Neuropathology and Experimental Neurology. PMID 27235405 DOI: 10.1093/Jnen/Nlw037  0.748
2016 Choe M, Cortés E, Vonsattel JG, Kuo SH, Faust PL, Louis ED. Purkinje cell loss in essential tremor: Random sampling quantification and nearest neighbor analysis. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26861543 DOI: 10.1002/Mds.26490  0.737
2015 Louis ED, Rabinowitz D, Choe M, Tate WJ, Kelly GC, Kuo SH, Faust PL. Mapping Purkinje Cell Placement Along the Purkinje Cell Layer: an Analysis of Postmortem Tissue from Essential Tremor Patients vs. Controls. Cerebellum (London, England). PMID 26563297 DOI: 10.1007/S12311-015-0742-0  0.43
2015 Louis RJ, Lin CY, Faust PL, Koeppen AH, Kuo SH. Climbing fiber synaptic changes correlate with clinical features in essential tremor. Neurology. 84: 2284-6. PMID 25948728 DOI: 10.1212/Wnl.0000000000001636  0.449
2014 Lee M, Cheng MM, Lin CY, Louis ED, Faust PL, Kuo SH. Decreased EAAT2 protein expression in the essential tremor cerebellar cortex. Acta Neuropathologica Communications. 2: 157. PMID 25391854 DOI: 10.1186/S40478-014-0157-Z  0.355
2014 Louis ED, Lee M, Babij R, Ma K, Cortés E, Vonsattel JP, Faust PL. Reduced Purkinje cell dendritic arborization and loss of dendritic spines in essential tremor. Brain : a Journal of Neurology. 137: 3142-8. PMID 25367027 DOI: 10.1093/Brain/Awu314  0.4
2014 Louis RJ, Lee M, Kuo SH, Vonsattel JP, Louis ED, Faust PL. Cellular density in the cerebellar molecular layer in essential tremor, spinocerebellar ataxia, and controls. Parkinsonism & Related Disorders. 20: 1270-3. PMID 25218844 DOI: 10.1016/J.Parkreldis.2014.08.014  0.424
2014 Louis ED, Faust PL. Purkinje cell loss in essential tremor. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1329-30. PMID 25042039 DOI: 10.1002/Mds.25965  0.395
2014 Louis ED, Lee M, Cortés E, Vonsattel JP, Faust PL. Matching asymmetry of tremor with asymmetry of postmortem cerebellar hemispheric changes in essential tremor. Cerebellum (London, England). 13: 462-70. PMID 24756341 DOI: 10.1007/S12311-014-0560-9  0.435
2014 Pan JJ, Lee M, Honig LS, Vonsattel JP, Faust PL, Louis ED. Alzheimer's-related changes in non-demented essential tremor patients vs. controls: links between tau and tremor? Parkinsonism & Related Disorders. 20: 655-8. PMID 24679899 DOI: 10.1016/J.Parkreldis.2014.03.003  0.435
2014 Louis ED, Kuo SH, Vonsattel JP, Faust PL. Torpedo formation and Purkinje cell loss: modeling their relationship in cerebellar disease. Cerebellum (London, England). 13: 433-9. PMID 24590661 DOI: 10.1007/S12311-014-0556-5  0.443
2014 Gillman A, Babij R, Lee M, Moskowitz C, Faust PL, Louis ED. Reflections: neurology and the humanities. Odd harvest. Neurology. 82: 184-6. PMID 24571012 DOI: 10.1212/Wnl.0000000000000021  0.302
2014 Hiebler S, Masuda T, Hacia JG, Moser AB, Faust PL, Liu A, Chowdhury N, Huang N, Lauer A, Bennett J, Watkins PA, Zack DJ, Braverman NE, Raymond GV, Steinberg SJ. The Pex1-G844D mouse: a model for mild human Zellweger spectrum disorder. Molecular Genetics and Metabolism. 111: 522-32. PMID 24503136 DOI: 10.1016/J.Ymgme.2014.01.008  0.322
2013 Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, et al. A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS. Nature Cell Biology. 15: 1186-96. PMID 23955302 DOI: 10.1038/Ncb2822  0.533
2013 Kuo SH, Tang G, Louis ED, Ma K, Babji R, Balatbat M, Cortes E, Vonsattel JP, Yamamoto A, Sulzer D, Faust PL. Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau. Acta Neuropathologica. 125: 879-89. PMID 23543187 DOI: 10.1007/S00401-013-1108-7  0.478
2013 Louis ED, Babij R, Cortés E, Vonsattel JP, Faust PL. The inferior olivary nucleus: a postmortem study of essential tremor cases versus controls. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 779-86. PMID 23483605 DOI: 10.1002/Mds.25400  0.337
2012 Kuo SH, Tang G, Ma K, Babij R, Cortes E, Vonsattel JP, Faust PL, Sulzer D, Louis ED. Macroautophagy abnormality in essential tremor. Plos One. 7: e53040. PMID 23300858 DOI: 10.1371/Journal.Pone.0053040  0.405
2012 Louis ED, Faust PL, Vonsattel JP. Purkinje cell loss is a characteristic of essential tremor: towards a more mature understanding of pathogenesis. Parkinsonism & Related Disorders. 18: 1003-4. PMID 22795481 DOI: 10.1016/J.Parkreldis.2012.06.017  0.344
2012 Louis ED, Ma K, Babij R, Cortés E, Liem RK, Vonsattel JP, Faust PL. Neurofilament protein levels: quantitative analysis in essential tremor cerebellar cortex. Neuroscience Letters. 518: 49-54. PMID 22561033 DOI: 10.1016/J.Neulet.2012.04.054  0.409
2012 Yu M, Ma K, Faust PL, Honig LS, Cortés E, Vonsattel JP, Louis ED. Increased number of Purkinje cell dendritic swellings in essential tremor. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 19: 625-30. PMID 22136494 DOI: 10.1111/J.1468-1331.2011.03598.X  0.487
2012 Louis E, Yu M, Ma K, Faust P, Honig L, Cortes E, Vonsattel J. Increased Number of Purkinje Cell Dendritic Swellings: Evidence of Another Structural Abnormality in Essential Tremor (P04.043) Neurology. 78: P04.043-P04.043. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P04.043  0.306
2011 Louis ED, Faust PL, Ma KJ, Yu M, Cortes E, Vonsattel JP. Torpedoes in the cerebellar vermis in essential tremor cases vs. controls. Cerebellum (London, England). 10: 812-9. PMID 21656041 DOI: 10.1007/S12311-011-0291-0  0.511
2011 Louis ED, Faust PL, Vonsattel JP. Purkinje cell loss is a characteristic of essential tremor. Parkinsonism & Related Disorders. 17: 406-9. PMID 21600832 DOI: 10.1016/J.Parkreldis.2011.05.004  0.472
2011 Kuo SH, Faust PL, Vonsattel JP, Ma K, Louis ED. Parallel fiber counts and parallel fiber integrated density are similar in essential tremor cases and controls. Acta Neuropathologica. 121: 287-9. PMID 21080179 DOI: 10.1007/S00401-010-0776-9  0.482
2011 Kuo SH, Erickson-Davis C, Gillman A, Faust PL, Vonsattel JP, Louis ED. Increased number of heterotopic Purkinje cells in essential tremor. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 1038-40. PMID 20802031 DOI: 10.1136/Jnnp.2010.213330  0.496
2011 Louis ED, Asabere N, Agnew A, Moskowitz CB, Lawton A, Cortes E, Faust PL, Vonsattel JP. Rest tremor in advanced essential tremor: a post-mortem study of nine cases. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 261-5. PMID 20802027 DOI: 10.1136/Jnnp.2010.215681  0.443
2010 Faust PL, Kaye EM, Powers JM. Myelin lesions associated with lysosomal and peroxisomal disorders. Expert Review of Neurotherapeutics. 10: 1449-66. PMID 20819015 DOI: 10.1586/Ern.10.127  0.355
2010 Erickson-Davis CR, Faust PL, Vonsattel JP, Gupta S, Honig LS, Louis ED. "Hairy baskets" associated with degenerative Purkinje cell changes in essential tremor. Journal of Neuropathology and Experimental Neurology. 69: 262-71. PMID 20142764 DOI: 10.1097/Nen.0B013E3181D1Ad04  0.527
2010 Louis ED, Erickson-Davis C, Pahwa R, Lyons KE, Garber A, Moskowitz CB, Lawton A, Faust PL, Vonsattel JP. Essential tremor with ubiquitinated Purkinje cell intranuclear inclusions. Acta Neuropathologica. 119: 375-7. PMID 20107820 DOI: 10.1007/S00401-010-0641-X  0.499
2010 Yakunin E, Moser A, Loeb V, Saada A, Faust P, Crane DI, Baes M, Sharon R. alpha-Synuclein abnormalities in mouse models of peroxisome biogenesis disorders. Journal of Neuroscience Research. 88: 866-76. PMID 19830841 DOI: 10.1002/Jnr.22246  0.318
2009 Louis ED, Faust PL, Vonsattel JP, Honig LS, Henchcliffe C, Pahwa R, Lyons KE, Rios E, Erickson-Davis C, Moskowitz CB, Lawton A. Older onset essential tremor: More rapid progression and more degenerative pathology. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 1606-12. PMID 19526587 DOI: 10.1002/Mds.22570  0.364
2009 Louis ED, Faust PL, Vonsattel JP, Honig LS, Rajput A, Rajput A, Pahwa R, Lyons KE, Ross WG, Elble RJ, Erickson-Davis C, Moskowitz CB, Lawton A. Torpedoes in Parkinson's disease, Alzheimer's disease, essential tremor, and control brains. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 1600-5. PMID 19526585 DOI: 10.1002/Mds.22567  0.477
2009 Louis ED, Faust PL, Vonsattel JP, Erickson-Davis C. Purkinje cell axonal torpedoes are unrelated to advanced aging and likely reflect cerebellar injury. Acta Neuropathologica. 117: 719-21. PMID 19360423 DOI: 10.1007/S00401-009-0534-Z  0.352
2009 Louis ED, Yi H, Erickson-Davis C, Vonsattel JP, Faust PL. Structural study of Purkinje cell axonal torpedoes in essential tremor. Neuroscience Letters. 450: 287-91. PMID 19047012 DOI: 10.1016/J.Neulet.2008.11.043  0.469
2008 Axelrad JE, Louis ED, Honig LS, Flores I, Ross GW, Pahwa R, Lyons KE, Faust PL, Vonsattel JP. Reduced Purkinje cell number in essential tremor: a postmortem study. Archives of Neurology. 65: 101-7. PMID 18195146 DOI: 10.1001/Archneurol.2007.8  0.467
2007 Louis ED, Faust PL, Vonsattel JP, Honig LS, Rajput A, Robinson CA, Rajput A, Pahwa R, Lyons KE, Ross GW, Borden S, Moskowitz CB, Lawton A, Hernandez N. Neuropathological changes in essential tremor: 33 cases compared with 21 controls. Brain : a Journal of Neurology. 130: 3297-307. PMID 18025031 DOI: 10.1093/Brain/Awm266  0.36
2003 Faust PL. Abnormal cerebellar histogenesis in PEX2 Zellweger mice reflects multiple neuronal defects induced by peroxisome deficiency. The Journal of Comparative Neurology. 461: 394-413. PMID 12746876 DOI: 10.1002/Cne.10699  0.344
2001 Faust PL, Su HM, Moser A, Moser HW. The peroxisome deficient PEX2 Zellweger mouse: pathologic and biochemical correlates of lipid dysfunction. Journal of Molecular Neuroscience : Mn. 16: 289-97; discussion 3. PMID 11478384 DOI: 10.1385/Jmn:16:2-3:289  0.335
1993 McDonald TD, Faust PL, Bruno C, DiMauro S, Goldman JE. Polyglucosan body disease simulating amyotrophic lateral sclerosis. Neurology. 43: 785-90. PMID 8469341 DOI: 10.1212/Wnl.43.4.785  0.342
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