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Amanda B. Hummon - Publications

Affiliations: 
Chemistry & Biochemistry University of Notre Dame, Notre Dame, IN, United States 
Area:
transcriptome and the proteome in cancer cells
Website:
http://chemistry.nd.edu/faculty/detail/ahummon/

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Buechler SA, Stephens MT, Hummon AB, Ludwig K, Cannon E, Carter TC, Resnick J, Gökmen-Polar Y, Badve SS. ColoType: a forty gene signature for consensus molecular subtyping of colorectal cancer tumors using whole-genome assay or targeted RNA-sequencing. Scientific Reports. 10: 12123. PMID 32694712 DOI: 10.1038/S41598-020-69083-Y  0.357
2019 Wangsa D, Braun R, Stuelten CH, Brown M, Bauer KM, Emons G, Weston LA, Hu Y, Yang HH, Vila-Casadesús M, Lee MP, Brauer P, Warner L, Upender M, Hummon AB, et al. Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells. Neoplasia (New York, N.Y.). 21: 721-729. PMID 31174021 DOI: 10.1016/J.Neo.2019.04.009  0.544
2019 Georgiadis RA, Stark A, Hummon AB. Abstract 2075: MAPK pathway expression in platinum-treated cancers Cancer Research. 79: 2075-2075. DOI: 10.1158/1538-7445.Sabcs18-2075  0.367
2018 Liu X, Lukowski JK, Flinders C, Georgiadis R, Kim S, Mumenthaler S, Hummon AB. MALDI-MSI of Immunotherapy: Mapping the EGFR-Targeting Antibody Cetuximab in 3D Colon Cancer Cell Cultures. Analytical Chemistry. PMID 30479121 DOI: 10.1021/Acs.Analchem.8B02151  0.328
2018 Schroll MM, Ludwig KR, LaBonia GJ, Herring EL, Hummon AB. Combined Short-Term Glucose Starvation and Chemotherapy in 3D Colorectal Cancer Cell Culture Decreases 14-3-3 Family Protein Expression and Phenotypic Response to Therapy. Journal of the American Society For Mass Spectrometry. PMID 30019162 DOI: 10.1007/S13361-018-2013-Z  0.319
2018 Schroll MM, Hummon AB. Employing proteomics to understand the effects of nutritional intervention in cancer treatment. Analytical and Bioanalytical Chemistry. PMID 29974151 DOI: 10.1007/S00216-018-1219-Z  0.338
2018 Schroll MM, Ludwig KR, Bauer KM, Hummon AB. Calcitriol Supplementation Causes Decreases in Tumorigenic Proteins and Different Proteomic and Metabolomic Signatures in Right versus Left-Sided Colon Cancer. Metabolites. 8. PMID 29324674 DOI: 10.3390/Metabo8010005  0.332
2018 Buechler SA, Badve SS, Gokmen-Polar Y, Herring E, Ludwig K, Hummon A. ColotypeR: A tool to classify colon cancers by consensus molecular subtype and subtype-specific risk of recurrence. Journal of Clinical Oncology. 36: 632-632. DOI: 10.1200/Jco.2018.36.4_Suppl.632  0.325
2018 Sen N, Ludwig K, Rangel-Rivera GO, Kim S, Huppi K, Jenkins L, Dwyer JE, Hoover S, Helman L, Simpson M, Mendoza A, Hummon AB, Caplen NJ. Abstract IA04: Targeting the expression of EWS-FLI1 Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-Ia04  0.353
2017 Feist PE, Loughran EA, Stack MS, Hummon AB. Quantitative proteomic analysis of murine white adipose tissue for peritoneal cancer metastasis. Analytical and Bioanalytical Chemistry. PMID 29282499 DOI: 10.1007/S00216-017-0813-9  0.322
2017 LaBonia GJ, Ludwig KR, Mousseau CB, Hummon AB. iTRAQ Quantitative Proteomic Profiling and MALDI-MSI of Colon Cancer Spheroids Treated with Combination Chemotherapies in a 3D Printed Fluidic Device. Analytical Chemistry. PMID 29227110 DOI: 10.1021/Acs.Analchem.7B04969  0.345
2017 Liu X, Flinders C, Mumenthaler SM, Hummon AB. MALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids. Journal of the American Society For Mass Spectrometry. PMID 29209911 DOI: 10.1007/S13361-017-1851-4  0.315
2017 Bailey KA, Klymenko Y, Feist PE, Hummon AB, Stack MS, Schultz ZD. Chemical Analysis of Morphological Changes in Lysophosphatidic Acid-Treated Ovarian Cancer Cells. Scientific Reports. 7: 15295. PMID 29127342 DOI: 10.1038/S41598-017-15547-7  0.344
2017 Zhang G, Vilim FS, Liu DD, Romanova EV, Yu K, Yuan WD, Xiao H, Hummon AB, Chen TT, Alexeeva V, Yin SY, Chen SA, Cropper EC, Sweedler JV, Weiss KR, et al. Discovery of leucokinin-like neuropeptides that modulate a specific parameter of feeding motor programs in the molluscan model, Aplysia. The Journal of Biological Chemistry. PMID 28924050 DOI: 10.1074/Jbc.M117.795450  0.621
2017 Boyce MW, LaBonia GJ, Hummon AB, Lockett MR. Assessing chemotherapeutic effectiveness using a paper-based tumor model. The Analyst. PMID 28702529 DOI: 10.1039/C7An00806F  0.312
2017 Schroll MM, LaBonia GJ, Ludwig KR, Hummon AB. Glucose restriction combined with autophagy inhibition and chemotherapy in HCT 116 spheroids decreases cell clonogenicity and viability regulated by tumor suppressor genes. Journal of Proteome Research. PMID 28650662 DOI: 10.1021/Acs.Jproteome.7B00293  0.348
2017 Feist PE, Sidoli S, Liu X, Schroll MM, Rahmy S, Fujiwara R, Garcia BA, Hummon AB. Multicellular Tumor Spheroids Combined with Mass Spectrometric Histone Analysis to Evaluate Epigenetic Drugs. Analytical Chemistry. PMID 28194967 DOI: 10.1021/Acs.Analchem.6B03602  0.307
2017 Schroll MM, Schultz ZD, Hummon AB. Abstract B42: Combination of liquid chromatography-surface enhanced Raman spectroscopy and liquid chromatography-mass spectrometry to identify SUMOylated proteins due to nutrient restriction in colorectal cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-B42  0.386
2016 Schunter AJ, Yue X, Hummon AB. Phosphoproteomics of colon cancer metastasis: comparative mass spectrometric analysis of the isogenic primary and metastatic cell lines SW480 and SW620. Analytical and Bioanalytical Chemistry. PMID 27987026 DOI: 10.1007/S00216-016-0125-5  0.376
2016 Schroll MM, Liu X, Herzog SK, Skube SB, Hummon AB. Nutrient restriction of glucose or serum results in similar proteomic expression changes in 3D colon cancer cell cultures. Nutrition Research (New York, N.Y.). 36: 1068-1080. PMID 27865348 DOI: 10.1016/J.Nutres.2016.08.002  0.353
2016 Yue X, Lukowski JK, Weaver EM, Skube SB, Hummon AB. Quantitative Proteomic and Phosphoproteomic Comparison of 2D and 3D Colon Cancer Cell Culture Models. Journal of Proteome Research. PMID 27696853 DOI: 10.1021/Acs.Jproteome.6B00342  0.33
2016 LaBonia GJ, Lockwood SY, Heller AA, Spence DM, Hummon AB. Drug penetration and metabolism in 3-dimensional cell cultures treated in a 3D printed fluidic device: Assessment of irinotecan via MALDI imaging mass spectrometry. Proteomics. PMID 27198560 DOI: 10.1002/Pmic.201500524  0.309
2016 Huang W, Feist P, Hummon A, Hill R. Abstract A05: Proteomic analysis of exosome content changes induced by gemcitabine in pancreatic cancer stromal cells Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A05  0.358
2015 Weaver EM, Hummon AB, Keithley RB. Chemometric analysis of MALDI mass spectrometric images of three-dimensional cell culture systems. Analytical Methods : Advancing Methods and Applications. 7: 7208-7219. PMID 26604989 DOI: 10.1039/C5Ay00293A  0.322
2015 Feist PE, Sun L, Liu X, Dovichi NJ, Hummon AB. Bottom-up proteomic analysis of single HCT 116 colon carcinoma multicellular spheroids. Rapid Communications in Mass Spectrometry : Rcm. 29: 654-8. PMID 26212283 DOI: 10.1002/Rcm.7150  0.311
2015 Liu X, Hummon AB. Mass Spectrometry Imaging of Therapeutics from Animal Models to Three-Dimensional Cell Cultures. Analytical Chemistry. PMID 26084404 DOI: 10.1021/Acs.Analchem.5B00419  0.316
2015 Feist P, Hummon AB. Proteomic challenges: sample preparation techniques for microgram-quantity protein analysis from biological samples. International Journal of Molecular Sciences. 16: 3537-63. PMID 25664860 DOI: 10.3390/Ijms16023537  0.303
2015 Liu X, Hummon AB. Quantitative determination of irinotecan and the metabolite SN-38 by nanoflow liquid chromatography-tandem mass spectrometry in different regions of multicellular tumor spheroids. Journal of the American Society For Mass Spectrometry. 26: 577-86. PMID 25604392 DOI: 10.1007/S13361-014-1071-0  0.303
2015 Yue X, Hummon A. Abstract B48: Modeling of EMT process in 3D cultures and proteomic analysis of differential protein expression in EMT related drug resistance in colorectal cancer cells Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-B48  0.343
2014 Ahlf Wheatcraft DR, Liu X, Hummon AB. Sample preparation strategies for mass spectrometry imaging of 3D cell culture models. Journal of Visualized Experiments : Jove. PMID 25549242 DOI: 10.3791/52313  0.328
2014 Bauer KM, Watts TN, Buechler S, Hummon AB. Proteomic and functional investigation of the colon cancer relapse-associated genes NOX4 and ITGA3. Journal of Proteome Research. 13: 4910-8. PMID 25096929 DOI: 10.1021/Pr500557N  0.373
2014 Ahlf DR, Masyuko RN, Hummon AB, Bohn PW. Correlated mass spectrometry imaging and confocal Raman microscopy for studies of three-dimensional cell culture sections. The Analyst. 139: 4578-85. PMID 25030970 DOI: 10.1039/C4An00826J  0.504
2013 Weston LA, Bauer KM, Hummon AB. Comparison of bottom-up proteomic approaches for LC-MS analysis of complex proteomes. Analytical Methods : Advancing Methods and Applications. 5. PMID 24288579 DOI: 10.1039/C3Ay40853A  0.332
2013 Liu X, Weaver EM, Hummon AB. Evaluation of therapeutics in three-dimensional cell culture systems by MALDI imaging mass spectrometry. Analytical Chemistry. 85: 6295-302. PMID 23724927 DOI: 10.1021/Ac400519C  0.312
2013 Padilla-Nash HM, McNeil NE, Yi M, Nguyen QT, Hu Y, Wangsa D, Mack DL, Hummon AB, Case C, Cardin E, Stephens R, Difilippantonio MJ, Ried T. Aneuploidy, oncogene amplification and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells. Carcinogenesis. 34: 1929-39. PMID 23619298 DOI: 10.1093/Carcin/Bgt138  0.708
2013 Weaver EM, Hummon AB. Imaging mass spectrometry: from tissue sections to cell cultures. Advanced Drug Delivery Reviews. 65: 1039-55. PMID 23571020 DOI: 10.1016/J.Addr.2013.03.006  0.313
2013 Camps J, Pitt JJ, Emons G, Hummon AB, Case CM, Grade M, Jones TL, Nguyen QT, Ghadimi BM, Beissbarth T, Difilippantonio MJ, Caplen NJ, Ried T. Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer. Cancer Research. 73: 2003-13. PMID 23319804 DOI: 10.1158/0008-5472.CAN-12-3159  0.704
2013 Liu X, Weaver E, Hummon AB. Abstract 3219: DrIMS-3DCC: Drug imaging mass spectrometry of 3D cell culture systems. Cancer Research. 73: 3219-3219. DOI: 10.1158/1538-7445.Am2013-3219  0.335
2013 Bauer KM, Buechler S, Hummon AB. Abstract 3218: Interrogating the role of NOX4 in colon cancer metastasis. Cancer Research. 73: 3218-3218. DOI: 10.1158/1538-7445.Am2013-3218  0.383
2012 Bauer KM, Lambert PA, Hummon AB. Comparative label-free LC-MS/MS analysis of colorectal adenocarcinoma and metastatic cells treated with 5-fluorouracil. Proteomics. 12: 1928-37. PMID 22623418 DOI: 10.1002/Pmic.201200041  0.336
2012 Hummon AB, Pitt JJ, Camps J, Emons G, Skube SB, Huppi K, Jones TL, Beissbarth T, Kramer F, Grade M, Difilippantonio MJ, Ried T, Caplen NJ. Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells. Molecular Cancer. 11: 1. PMID 22216762 DOI: 10.1186/1476-4598-11-1  0.717
2012 Bauer KM, Hummon AB, Buechler S. Right-side and left-side colon cancer follow different pathways to relapse. Molecular Carcinogenesis. 51: 411-21. PMID 21656576 DOI: 10.1002/Mc.20804  0.349
2012 Hummon AB, Li H, Weaver E. Abstract 1281: MALDI imaging mass spectrometry of three-dimensional cell culture systems Cancer Research. 72: 1281-1281. DOI: 10.1158/1538-7445.Am2012-1281  0.369
2012 Yue XS, Hummon AB. Mass spectrometry-based phosphoproteomics in cancer research Frontiers in Biology. 7: 566-586. DOI: 10.1007/S11515-012-2022-4  0.332
2011 Li H, Hummon AB. Imaging mass spectrometry of three-dimensional cell culture systems. Analytical Chemistry. 83: 8794-801. PMID 21992577 DOI: 10.1021/Ac202356G  0.324
2011 Grade M, Hummon AB, Camps J, Emons G, Spitzner M, Gaedcke J, Hoermann P, Ebner R, Becker H, Difilippantonio MJ, Ghadimi BM, Beissbarth T, Caplen NJ, Ried T. A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets. International Journal of Cancer. Journal International Du Cancer. 128: 1069-79. PMID 20473941 DOI: 10.1002/Ijc.25453  0.717
2009 Camps J, Nguyen QT, Padilla-Nash HM, Knutsen T, McNeil NE, Wangsa D, Hummon AB, Grade M, Ried T, Difilippantonio MJ. Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer. Genes, Chromosomes & Cancer. 48: 1002-17. PMID 19691111 DOI: 10.1002/Gcc.20699  0.72
2008 Camps J, Grade M, Nguyen QT, Hörmann P, Becker S, Hummon AB, Rodriguez V, Chandrasekharappa S, Chen Y, Difilippantonio MJ, Becker H, Ghadimi BM, Ried T. Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome. Cancer Research. 68: 1284-95. PMID 18316590 DOI: 10.1158/0008-5472.Can-07-2864  0.695
2008 Grade M, Hummon A, Camps J, Emons G, Spitzner M, Gaedcke J, Difilippantonio M, Ghadimi B, Caplen N, Ried T. 551 POSTER RNAi-based identification of potential targets in colorectal cancers European Journal of Cancer Supplements. 6: 174. DOI: 10.1016/S1359-6349(08)72485-6  0.678
2007 Hummon AB, Lim SR, Difilippantonio MJ, Ried T. Isolation and solubilization of proteins after TRIzol extraction of RNA and DNA from patient material following prolonged storage. Biotechniques. 42: 467-70, 472. PMID 17489233 DOI: 10.2144/000112401  0.667
2007 Grade M, Hörmann P, Becker S, Hummon AB, Wangsa D, Varma S, Simon R, Liersch T, Becker H, Difilippantonio MJ, Ghadimi BM, Ried T. Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas. Cancer Research. 67: 41-56. PMID 17210682 DOI: 10.1158/0008-5472.Can-06-1514  0.685
2006 Hummon AB, Richmond TA, Verleyen P, Baggerman G, Huybrechts J, Ewing MA, Vierstraete E, Rodriguez-Zas SL, Schoofs L, Robinson GE, Sweedler JV. From the genome to the proteome: uncovering peptides in the Apis brain. Science (New York, N.Y.). 314: 647-9. PMID 17068263 DOI: 10.1126/Science.1124128  0.489
2006 Amare A, Hummon AB, Southey BR, Zimmerman TA, Rodriguez-Zas SL, Sweedler JV. Bridging neuropeptidomics and genomics with bioinformatics: Prediction of mammalian neuropeptide prohormone processing. Journal of Proteome Research. 5: 1162-7. PMID 16674105 DOI: 10.1021/Pr0504541  0.703
2006 Hummon AB, Amare A, Sweedler JV. Discovering new invertebrate neuropeptides using mass spectrometry. Mass Spectrometry Reviews. 25: 77-98. PMID 15937922 DOI: 10.1002/Mas.20055  0.477
2004 Stuart JN, Hummon AB, Sweedler JV. The chemistry of thought: neurotransmitters in the brain. Analytical Chemistry. 76: 121A-128A. PMID 15101371  0.653
2004 Cummins SF, Nichols AE, Amare A, Hummon AB, Sweedler JV, Nagle GT. Characterization of Aplysia enticin and temptin, two novel water-borne protein pheromones that act in concert with attractin to stimulate mate attraction. The Journal of Biological Chemistry. 279: 25614-22. PMID 15054104 DOI: 10.1074/Jbc.M313585200  0.471
2004 Stuart JN, Hummon AB, Sweedler JV. Peer Reviewed: The Chemistry of Thought: Neurotransmitters in the Brain Analytical Chemistry. 76. DOI: 10.1021/Ac041534B  0.674
2003 Hummon AB, Hummon NP, Corbin RW, Li L, Vilim FS, Weiss KR, Sweedler JV. From precursor to final peptides: a statistical sequence-based approach to predicting prohormone processing. Journal of Proteome Research. 2: 650-6. PMID 14692459 DOI: 10.1021/Pr034046D  0.553
2003 Hummon AB, Sweedler JV, Corbin RW. Discovering new neuropeptides using single-cell mass spectrometry Trac - Trends in Analytical Chemistry. 22: 515-521. DOI: 10.1016/S0165-9936(03)00901-4  0.479
2002 Hummon AB, Kelley WP, Sweedler JV. A novel prohormone processing site in Aplysia californica: the Leu-Leu rule. Journal of Neurochemistry. 82: 1398-405. PMID 12354287 DOI: 10.1046/J.1471-4159.2002.01070.X  0.667
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