Year |
Citation |
Score |
2022 |
Araujo JA, Segarra S, Mendes J, Paradis A, Brooks M, Thevarkunnel S, Milgram NW. Sphingolipids and DHA Improve Cognitive Deficits in Aged Beagle Dogs. Frontiers in Veterinary Science. 9: 646451. PMID 35909696 DOI: 10.3389/fvets.2022.646451 |
0.371 |
|
2018 |
Pan Y, Landsberg G, Mougeot I, Kelly S, Xu H, Bhatnagar S, Gardner CL, Milgram NW. Efficacy of a Therapeutic Diet on Dogs With Signs of Cognitive Dysfunction Syndrome (CDS): A Prospective Double Blinded Placebo Controlled Clinical Study. Frontiers in Nutrition. 5: 127. PMID 30619873 DOI: 10.3389/Fnut.2018.00127 |
0.33 |
|
2017 |
Snigdha S, Yassa MA, deRivera C, Milgram NW, Cotman CW. Pattern separation and goal-directed behavior in the aged canine. Learning & Memory (Cold Spring Harbor, N.Y.). 24: 123-131. PMID 28202716 DOI: 10.1101/Lm.043422.116 |
0.401 |
|
2016 |
Zanghi BM, Gardner C, Araujo J, Milgram NW. Diurnal changes in core body temperature, day/night locomotor activity patterns, and actigraphy-generated behavioral sleep in aged canines with varying levels of cognitive dysfunction Neurobiology of Sleep and Circadian Rhythms. 1: 8-18. DOI: 10.1016/J.Nbscr.2016.07.001 |
0.364 |
|
2015 |
Snigdha S, de Rivera C, Milgram NW, Cotman CW. Effect of mitochondrial cofactors and antioxidants supplementation on cognition in the aged canine. Neurobiology of Aging. PMID 26481404 DOI: 10.1016/J.Neurobiolaging.2015.09.015 |
0.412 |
|
2015 |
Zanghi BM, Araujo J, Milgram NW. Cognitive domains in the dog: independence of working memory from object learning, selective attention, and motor learning. Animal Cognition. 18: 789-800. PMID 25677729 DOI: 10.1007/S10071-015-0847-3 |
0.41 |
|
2015 |
Milgram NW, Landsberg G, Merrick D, Underwood MY. A novel mechanism for cognitive enhancement in aged dogs with the use of a calcium-buffering protein Journal of Veterinary Behavior: Clinical Applications and Research. 10: 217-222. DOI: 10.1016/J.Jveb.2015.02.003 |
0.434 |
|
2014 |
Snigdha S, de Rivera C, Milgram NW, Cotman CW. Exercise enhances memory consolidation in the aging brain. Frontiers in Aging Neuroscience. 6: 3. PMID 24550824 DOI: 10.3389/Fnagi.2014.00003 |
0.338 |
|
2014 |
Lazarowski L, Foster ML, Gruen ME, Sherman BL, Case BC, Fish RE, Milgram NW, Dorman DC. Acquisition of a visual discrimination and reversal learning task by Labrador retrievers. Animal Cognition. 17: 787-92. PMID 24277162 DOI: 10.1007/S10071-013-0712-1 |
0.395 |
|
2013 |
Snigdha S, Milgram NW, Willis SL, Albert M, Weintraub S, Fortin NJ, Cotman CW. A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap. Neurobiology of Aging. 34: 1891-901. PMID 23434040 DOI: 10.1016/J.Neurobiolaging.2013.01.018 |
0.423 |
|
2013 |
Pan Y, Araujo JA, Burrows J, de Rivera C, Gore A, Bhatnagar S, Milgram NW. Cognitive enhancement in middle-aged and old cats with dietary supplementation with a nutrient blend containing fish oil, B vitamins, antioxidants and arginine. The British Journal of Nutrition. 110: 40-9. PMID 23211671 DOI: 10.1017/S0007114512004771 |
0.432 |
|
2013 |
Araujo JA, de Rivera C, Landsberg GM, Adams PE, Milgram NW. Development and validation of a novel laboratory model of sound-induced fear and anxiety in Beagle dogs Journal of Veterinary Behavior: Clinical Applications and Research. 8: 204-212. DOI: 10.1016/J.Jveb.2012.10.008 |
0.3 |
|
2012 |
Zicker SC, Jewell DE, Yamka RM, Milgram NW. Evaluation of cognitive learning, memory, psychomotor, immunologic, and retinal functions in healthy puppies fed foods fortified with docosahexaenoic acid-rich fish oil from 8 to 52 weeks of age. Journal of the American Veterinary Medical Association. 241: 583-94. PMID 22916855 DOI: 10.2460/Javma.241.5.583 |
0.337 |
|
2012 |
Snigdha S, Christie LA, De Rivera C, Araujo JA, Milgram NW, Cotman CW. Age and distraction are determinants of performance on a novel visual search task in aged Beagle dogs. Age (Dordrecht, Netherlands). 34: 67-73. PMID 21336566 DOI: 10.1007/S11357-011-9219-3 |
0.401 |
|
2012 |
Zanghi BM, Kerr W, de Rivera C, Araujo JA, Milgram NW. Effect of age and feeding schedule on diurnal rest/activity rhythms in dogs Journal of Veterinary Behavior: Clinical Applications and Research. 7: 339-347. DOI: 10.1016/J.Jveb.2012.01.004 |
0.343 |
|
2011 |
Araujo JA, Greig NH, Ingram DK, Sandin J, de Rivera C, Milgram NW. Cholinesterase inhibitors improve both memory and complex learning in aged beagle dogs. Journal of Alzheimer's Disease : Jad. 26: 143-55. PMID 21593569 DOI: 10.3233/Jad-2011-110005 |
0.442 |
|
2011 |
Araujo JA, Nobrega JN, Raymond R, Milgram NW. Aged dogs demonstrate both increased sensitivity to scopolamine impairment and decreased muscarinic receptor density. Pharmacology, Biochemistry, and Behavior. 98: 203-9. PMID 21238475 DOI: 10.1016/J.Pbb.2011.01.005 |
0.433 |
|
2011 |
Milgram N, Underwood M. P4-283: A novel mechanism for cognitive enhancement in aged dogs with the use of a calcium binding protein Alzheimer's & Dementia. 7: e10-e11. DOI: 10.1016/J.Jalz.2011.09.028 |
0.441 |
|
2011 |
Araujo JA, Higgins G, de Rivera C, Milgram N. P1-030: Evaluation of translational Alzheimer's disease biomarkers in the aged dog: The effects of age and bace inhibition on CSF amyloid Alzheimer's & Dementia. 7: S120-S120. DOI: 10.1016/J.Jalz.2011.05.310 |
0.373 |
|
2010 |
Pop V, Head E, Hill MA, Gillen D, Berchtold NC, Muggenburg BA, Milgram NW, Murphy MP, Cotman CW. Synergistic effects of long-term antioxidant diet and behavioral enrichment on beta-amyloid load and non-amyloidogenic processing in aged canines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9831-9. PMID 20660265 DOI: 10.1523/Jneurosci.6194-09.2010 |
0.349 |
|
2010 |
Pan Y, Larson B, Araujo JA, Lau W, de Rivera C, Santana R, Gore A, Milgram NW. Dietary supplementation with medium-chain TAG has long-lasting cognition-enhancing effects in aged dogs. The British Journal of Nutrition. 103: 1746-54. PMID 20141643 DOI: 10.1017/S0007114510000097 |
0.435 |
|
2010 |
Collison KS, Makhoul NJ, Inglis A, Al-Johi M, Zaidi MZ, Maqbool Z, Saleh SM, Bakheet R, Mondreal R, Al-Rabiah R, Shoukri M, Milgram NW, Al-Mohanna FA. Dietary trans-fat combined with monosodium glutamate induces dyslipidemia and impairs spatial memory. Physiology & Behavior. 99: 334-42. PMID 19945473 DOI: 10.1016/J.Physbeh.2009.11.010 |
0.321 |
|
2010 |
Araujo JA, de Rivera C, Ethier JL, Landsberg GM, Denenberg S, Arnold S, Milgram NW. ANXITANE® tablets reduce fear of human beings in a laboratory model of anxiety-related behavior Journal of Veterinary Behavior: Clinical Applications and Research. 5: 268-275. DOI: 10.1016/J.Jveb.2010.02.003 |
0.305 |
|
2009 |
Christie LA, Opii WO, Head E, Araujo JA, de Rivera C, Milgram NW, Cotman CW. Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles. Experimental Gerontology. 44: 752-9. PMID 19735717 DOI: 10.1016/J.Exger.2009.08.012 |
0.424 |
|
2009 |
Araujo JA, de Rivera C, Milgram NW, Sandin J. P4-316: Pharmacological Validation Of The Canine Model Of Alzheimer's Disease: Donepezil Improves Memory In Cognitively Impaired Aged Beagle Dogs Alzheimer's & Dementia. 5: e23-e23. DOI: 10.1016/J.Jalz.2009.07.095 |
0.397 |
|
2008 |
Araujo JA, Landsberg GM, Milgram NW, Miolo A. Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine. The Canadian Veterinary Journal. La Revue VéTéRinaire Canadienne. 49: 379-85. PMID 18481547 |
0.331 |
|
2008 |
Siwak-Tapp CT, Head E, Muggenburg BA, Milgram NW, Cotman CW. Region specific neuron loss in the aged canine hippocampus is reduced by enrichment. Neurobiology of Aging. 29: 39-50. PMID 17092609 DOI: 10.1016/J.Neurobiolaging.2006.09.018 |
0.348 |
|
2008 |
Araujo JA, de Rivera C, Milgram NW. P1-001: Visual attention is decreased in aged dogs Alzheimer's & Dementia. 4: T205-T206. DOI: 10.1016/J.Jalz.2008.05.586 |
0.313 |
|
2008 |
de Rivera C, Araujo JA, Dobson H, Zicker S, Milgram NW. IC-P1-016: Fractional anisotropy increases with development and is correlated with cognitive function in the beagle dog Alzheimer's & Dementia. 4: T15-T15. DOI: 10.1016/J.Jalz.2008.05.027 |
0.391 |
|
2007 |
Boutet I, Milgram NW, Freedman M. Cognitive decline and human (Homo sapiens) aging: an investigation using a comparative neuropsychological approach. Journal of Comparative Psychology (Washington, D.C. : 1983). 121: 270-81. PMID 17696653 DOI: 10.1037/0735-7036.121.3.270 |
0.409 |
|
2007 |
Milgram NW, Araujo JA, Hagen TM, Treadwell BV, Ames BN. Acetyl-L-carnitine and alpha-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3756-62. PMID 17622567 DOI: 10.1096/Fj.07-8531Com |
0.434 |
|
2007 |
Siwak-Tapp CT, Head E, Muggenburg BA, Milgram NW, Cotman CW. Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function. Neurobiology of Learning and Memory. 88: 249-59. PMID 17587610 DOI: 10.1016/J.Nlm.2007.05.001 |
0.413 |
|
2007 |
Nippak PM, Mendelson J, Muggenburg B, Milgram NW. Enhanced spatial ability in aged dogs following dietary and behavioural enrichment. Neurobiology of Learning and Memory. 87: 610-23. PMID 17303448 DOI: 10.1016/J.Nlm.2007.01.001 |
0.457 |
|
2006 |
Milgram NW, Siwak-Tapp CT, Araujo J, Head E. Neuroprotective effects of cognitive enrichment. Ageing Research Reviews. 5: 354-69. PMID 16949888 DOI: 10.1016/J.Arr.2006.04.004 |
0.379 |
|
2006 |
Studzinski CM, Christie LA, Araujo JA, Burnham WM, Head E, Cotman CW, Milgram NW. Visuospatial function in the beagle dog: an early marker of cognitive decline in a model of human aging and dementia. Neurobiology of Learning and Memory. 86: 197-204. PMID 16616528 DOI: 10.1016/J.Nlm.2006.02.005 |
0.48 |
|
2006 |
Nippak PM, Ikeda-Douglas C, Milgram NW. Extensive spatial training does not negate age differences in response latency. Brain Research. 1070: 171-88. PMID 16460702 DOI: 10.1016/J.Brainres.2005.11.026 |
0.429 |
|
2006 |
Tapp PD, Head K, Head E, Milgram NW, Muggenburg BA, Su MY. Application of an automated voxel-based morphometry technique to assess regional gray and white matter brain atrophy in a canine model of aging. Neuroimage. 29: 234-44. PMID 16275022 DOI: 10.1016/J.Neuroimage.2005.07.043 |
0.388 |
|
2006 |
Araujo JA, Chan AD, Milgram NW. A Scopolamine-Induced Model of Cognitive Dysfunction in Canines Cns Drug Reviews. 6: 43-43. DOI: 10.1111/J.1527-3458.2000.Tb00186.X |
0.314 |
|
2006 |
Araujo JA, Segarra S, Paradis A, Thevarkunnel S, Milgram NW. P4-214: SUPPLEMENTATION WITH A NOVEL LIPID EXTRACT IMPROVES FRONTAL LOBE LINKED COGNITIVE DEFICITS IN AN AGED BEAGLE MODEL OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1523-P1523. DOI: 10.1016/J.Jalz.2018.07.035 |
0.364 |
|
2006 |
Araujo JA, Nobrega JN, Raymond R, Milgram NW. P2-007: Functional and physiological cholinergic deficits in the aged dog: Extending the canine model of dementia and Alzheimer's disease Alzheimer's & Dementia. 2: S234-S234. DOI: 10.1016/J.Jalz.2006.05.844 |
0.357 |
|
2006 |
Henderson ST, Studzinski CM, Araujo JA, Milgram NW, Larson B. P4-382: Beneficial effects of AC1203 in a dog model of human aging and dementia Alzheimer's & Dementia. 2: S630-S630. DOI: 10.1016/J.Jalz.2006.05.2123 |
0.367 |
|
2005 |
Araujo JA, Studzinski CM, Head E, Cotman CW, Milgram NW. Assessment of nutritional interventions for modification of age-associated cognitive decline using a canine model of human aging. Age (Dordrecht, Netherlands). 27: 27-37. PMID 23598601 DOI: 10.1007/S11357-005-4001-Z |
0.439 |
|
2005 |
Roudebush P, Zicker SC, Cotman CW, Milgram NW, Muggenburg BA, Head E. Nutritional management of brain aging in dogs. Journal of the American Veterinary Medical Association. 227: 722-8. PMID 16178393 DOI: 10.2460/Javma.2005.227.722 |
0.318 |
|
2005 |
Studzinski CM, Araujo JA, Milgram NW. The canine model of human cognitive aging and dementia: pharmacological validity of the model for assessment of human cognitive-enhancing drugs. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 489-98. PMID 15795058 DOI: 10.1016/J.Pnpbp.2004.12.014 |
0.4 |
|
2005 |
Chan JW, Araujo JA, Zicker SC, Pun TW, Milgram NW. Effect of feeding patterns on performance of a visuospatial memory task in the beagle dog: a novel cognitive-based protocol for assessing satiety. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 481-8. PMID 15795057 DOI: 10.1016/J.Pnpbp.2004.12.013 |
0.384 |
|
2005 |
Siwak CT, Tapp PD, Head E, Zicker SC, Murphey HL, Muggenburg BA, Ikeda-Douglas CJ, Cotman CW, Milgram NW. Chronic antioxidant and mitochondrial cofactor administration improves discrimination learning in aged but not young dogs. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 461-9. PMID 15795055 DOI: 10.1016/J.Pnpbp.2004.12.011 |
0.472 |
|
2005 |
Nelson L, Johnson JK, Freedman M, Lott I, Groot J, Chang M, Milgram NW, Head E. Learning and memory as a function of age in Down syndrome: a study using animal-based tasks. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 443-53. PMID 15795053 DOI: 10.1016/J.Pnpbp.2004.12.009 |
0.454 |
|
2005 |
Boutet I, Ryan M, Kulaga V, McShane C, Christie LA, Freedman M, Milgram NW. Age-associated cognitive deficits in humans and dogs: a comparative neuropsychological approach. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 433-41. PMID 15795052 DOI: 10.1016/J.Pnpbp.2004.12.015 |
0.405 |
|
2005 |
Araujo JA, Studzinski CM, Milgram NW. Further evidence for the cholinergic hypothesis of aging and dementia from the canine model of aging. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 411-22. PMID 15795050 DOI: 10.1016/J.Pnpbp.2004.12.008 |
0.468 |
|
2005 |
Tapp PD, Chu Y, Araujo JA, Chiou JY, Head E, Milgram NW, Su MY. Effects of scopolamine challenge on regional cerebral blood volume. A pharmacological model to validate the use of contrast enhanced magnetic resonance imaging to assess cerebral blood volume in a canine model of aging. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 399-406. PMID 15795048 DOI: 10.1016/J.Pnpbp.2004.12.006 |
0.363 |
|
2005 |
de Rivera C, Boutet I, Zicker SC, Milgram NW. A novel method for assessing contrast sensitivity in the beagle dog is sensitive to age and an antioxidant enriched food. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 379-87. PMID 15795046 DOI: 10.1016/J.Pnpbp.2004.12.004 |
0.427 |
|
2005 |
Nippak PM, Milgram NW. An investigation of the relationship between response latency across several cognitive tasks in the beagle dog. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 371-7. PMID 15795045 DOI: 10.1016/J.Pnpbp.2004.12.003 |
0.371 |
|
2005 |
Christie LA, Studzinski CM, Araujo JA, Leung CS, Ikeda-Douglas CJ, Head E, Cotman CW, Milgram NW. A comparison of egocentric and allocentric age-dependent spatial learning in the beagle dog. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 361-9. PMID 15795044 DOI: 10.1016/J.Pnpbp.2004.12.002 |
0.373 |
|
2005 |
Milgram NW, Head E, Zicker SC, Ikeda-Douglas CJ, Murphey H, Muggenburg B, Siwak C, Tapp D, Cotman CW. Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study. Neurobiology of Aging. 26: 77-90. PMID 15585348 DOI: 10.1016/J.Neurobiolaging.2004.02.014 |
0.417 |
|
2004 |
Tapp PD, Siwak CT, Gao FQ, Chiou JY, Black SE, Head E, Muggenburg BA, Cotman CW, Milgram NW, Su MY. Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8205-13. PMID 15385603 DOI: 10.1523/Jneurosci.1339-04.2004 |
0.419 |
|
2004 |
Tapp PD, Siwak CT, Head E, Cotman CW, Murphey H, Muggenburg BA, Ikeda-Douglas C, Milgram NW. Concept abstraction in the aging dog: development of a protocol using successive discrimination and size concept tasks. Behavioural Brain Research. 153: 199-210. PMID 15219721 DOI: 10.1016/J.Bbr.2003.12.003 |
0.409 |
|
2004 |
Milgram NW, Head E, Zicker SC, Ikeda-Douglas C, Murphey H, Muggenberg BA, Siwak CT, Tapp PD, Lowry SR, Cotman CW. Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs. Experimental Gerontology. 39: 753-65. PMID 15130670 DOI: 10.1016/J.Exger.2004.01.007 |
0.425 |
|
2004 |
Tapp D, Siwak CT, Gao FQ, Chiou J, Black SE, Head E, Muggenburg BA, Cotman CW, Milgram NW, Su M. P3-066 Changes in frontal lobe volume, executive function, and amyloid load in a canine model of aging Neurobiology of Aging. 25: S371. DOI: 10.1016/S0197-4580(04)81218-1 |
0.327 |
|
2004 |
Araujo JA, Studzinski CM, Milgram NW. P2-022 The effects of age and scopolamine on skilled motor function in dogs: further evidence of age-dependent cholinergic dysfunction Neurobiology of Aging. 25: S230. DOI: 10.1016/S0197-4580(04)80770-X |
0.37 |
|
2003 |
Milgram NW. Cognitive experience and its effect on age-dependent cognitive decline in beagle dogs. Neurochemical Research. 28: 1677-82. PMID 14584821 DOI: 10.1023/A:1026009005108 |
0.477 |
|
2003 |
Nippak PM, Chan AD, Campbell Z, Muggenburg B, Head E, Ikeda-Douglas CJ, Murphey H, Cotman CW, Milgram NW. Response latency in Canis familiaris: mental ability or mental strategy? Behavioral Neuroscience. 117: 1066-75. PMID 14570555 DOI: 10.1037/0735-7044.117.5.1066 |
0.431 |
|
2003 |
Siwak CT, Tapp PD, Milgram NW. Adrafinil disrupts performance on a delayed nonmatching-to-position task in aged beagle dogs. Pharmacology, Biochemistry, and Behavior. 76: 161-8. PMID 13679229 DOI: 10.1016/S0091-3057(03)00211-9 |
0.426 |
|
2003 |
Siwak CT, Tapp PD, Zicker SC, Murphey HL, Muggenburg BA, Head E, Cotman CW, Milgram NW. Locomotor activity rhythms in dogs vary with age and cognitive status. Behavioral Neuroscience. 117: 813-24. PMID 12931965 DOI: 10.1037/0735-7044.117.4.813 |
0.415 |
|
2003 |
Tapp PD, Siwak CT, Estrada J, Holowachuk D, Milgram NW. Effects of age on measures of complex working memory span in the beagle dog (Canis familiaris) using two versions of a spatial list learning paradigm. Learning & Memory (Cold Spring Harbor, N.Y.). 10: 148-60. PMID 12663753 DOI: 10.1101/Lm.56503 |
0.373 |
|
2003 |
Tapp PD, Siwak CT, Estrada J, Head E, Muggenburg BA, Cotman CW, Milgram NW. Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging. Learning & Memory (Cold Spring Harbor, N.Y.). 10: 64-73. PMID 12551965 DOI: 10.1101/Lm.54403 |
0.451 |
|
2002 |
Milgram NW, Head E, Muggenburg B, Holowachuk D, Murphey H, Estrada J, Ikeda-Douglas CJ, Zicker SC, Cotman CW. Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy. Neuroscience and Biobehavioral Reviews. 26: 679-95. PMID 12479842 DOI: 10.1016/S0149-7634(02)00039-8 |
0.448 |
|
2002 |
Cotman CW, Head E, Muggenburg BA, Zicker S, Milgram NW. Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction. Neurobiology of Aging. 23: 809-18. PMID 12392784 DOI: 10.1016/S0197-4580(02)00073-8 |
0.466 |
|
2002 |
Milgram NW, Zicker SC, Head E, Muggenburg BA, Murphey H, Ikeda-Douglas CJ, Cotman CW. Dietary enrichment counteracts age-associated cognitive dysfunction in canines. Neurobiology of Aging. 23: 737-45. PMID 12392778 DOI: 10.1016/S0197-4580(02)00020-9 |
0.448 |
|
2002 |
Head E, Liu J, Hagen TM, Muggenburg BA, Milgram NW, Ames BN, Cotman CW. Oxidative damage increases with age in a canine model of human brain aging. Journal of Neurochemistry. 82: 375-81. PMID 12124438 DOI: 10.1046/J.1471-4159.2002.00969.X |
0.339 |
|
2002 |
Chan AD, Nippak PM, Murphey H, Ikeda-Douglas CJ, Muggenburg B, Head E, Cotman CW, Milgram NW. Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility. Behavioral Neuroscience. 116: 443-54. PMID 12049325 DOI: 10.1037/0735-7044.116.3.443 |
0.453 |
|
2002 |
Siwak CT, Murphey HL, Muggenburg BA, Milgram NW. Age-dependent decline in locomotor activity in dogs is environment specific. Physiology & Behavior. 75: 65-70. PMID 11890954 DOI: 10.1016/S0031-9384(01)00632-1 |
0.381 |
|
2001 |
Siwak CT, Tapp PD, Milgram NW. Effect of age and level of cognitive function on spontaneous and exploratory behaviors in the beagle dog. Learning & Memory (Cold Spring Harbor, N.Y.). 8: 317-25. PMID 11773431 DOI: 10.1101/Lm.41701 |
0.452 |
|
2000 |
Callahan H, Ikeda-Douglas C, Head E, Cotman CW, Milgram NW. Development of a protocol for studying object recognition memory in the dog. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 693-707. PMID 11191709 DOI: 10.1016/S0278-5846(00)00102-0 |
0.339 |
|
2000 |
Adams B, Chan A, Callahan H, Milgram NW. The canine as a model of human cognitive aging: recent developments. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 675-92. PMID 11191708 DOI: 10.1016/S0278-5846(00)00101-9 |
0.436 |
|
2000 |
Head E, Cotman CW, Milgram NW. Canine cognition, aging and neuropathology. Introduction. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 671-3. PMID 11191707 DOI: 10.1016/S0278-5846(00)00100-7 |
0.399 |
|
2000 |
Siwak CT, Gruet P, Woehrlé F, Muggenburg BA, Murphey HL, Milgram NW. Comparison of the effects of adrafinil, propentofylline, and nicergoline on behavior in aged dogs. American Journal of Veterinary Research. 61: 1410-4. PMID 11108188 DOI: 10.2460/Ajvr.2000.61.1410 |
0.374 |
|
2000 |
Milgram NW, Siwak CT, Gruet P, Atkinson P, Woehrlé F, Callahan H. Oral administration of adrafinil improves discrimination learning in aged beagle dogs. Pharmacology, Biochemistry, and Behavior. 66: 301-5. PMID 10880682 DOI: 10.1016/S0091-3057(00)00175-1 |
0.381 |
|
2000 |
Siwak CT, Gruet P, Woehrlé F, Schneider M, Muggenburg BA, Murphey HL, Callahan H, Milgram NW. Behavioral activating effects of adrafinil in aged canines. Pharmacology, Biochemistry, and Behavior. 66: 293-300. PMID 10880681 DOI: 10.1016/S0091-3057(00)00188-X |
0.331 |
|
2000 |
Head E, McCleary R, Hahn FF, Milgram NW, Cotman CW. Region-specific age at onset of beta-amyloid in dogs. Neurobiology of Aging. 21: 89-96. PMID 10794853 DOI: 10.1016/S0197-4580(00)00093-2 |
0.352 |
|
2000 |
Adams B, Chan A, Callahan H, Siwak C, Tapp D, Ikeda-Douglas C, Atkinson P, Head E, Cotman CW, Milgram NW. Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog. Behavioural Brain Research. 108: 47-56. PMID 10680756 DOI: 10.1016/S0166-4328(99)00132-1 |
0.454 |
|
1999 |
Morgan HD, Watchus JA, Milgram NW, Fleming AS. The long lasting effects of electrical simulation of the medial preoptic area and medial amygdala on maternal behavior in female rats. Behavioural Brain Research. 99: 61-73. PMID 10512573 DOI: 10.1016/S0166-4328(98)00070-9 |
0.302 |
|
1999 |
Milgram NW, Adams B, Callahan H, Head E, Mackay B, Thirlwell C, Cotman CW. Landmark discrimination learning in the dog. Learning & Memory (Cold Spring Harbor, N.Y.). 6: 54-61. PMID 10355524 DOI: 10.1101/Lm.6.1.54 |
0.362 |
|
1998 |
Head E, Callahan H, Muggenburg BA, Cotman CW, Milgram NW. Visual-discrimination learning ability and beta-amyloid accumulation in the dog. Neurobiology of Aging. 19: 415-25. PMID 9880044 DOI: 10.1016/S0197-4580(98)00084-0 |
0.394 |
|
1997 |
Cammisuli S, Murphy MP, Ikeda-Douglas CJ, Balkissoon V, Holsinger RM, Head E, Michael M, Racine RJ, Milgram NW. Effects of extended electrical kindling on exploratory behavior and spatial learning. Behavioural Brain Research. 89: 179-90. PMID 9475625 DOI: 10.1016/S0166-4328(97)00059-4 |
0.348 |
|
1997 |
Head E, Callahan H, Cummings BJ, Cotman CW, Ruehl WW, Muggenberg BA, Milgram NW. Open field activity and human interaction as a function of age and breed in dogs. Physiology & Behavior. 62: 963-71. PMID 9333188 DOI: 10.1016/S0031-9384(97)00198-4 |
0.422 |
|
1996 |
Head E, Hartley J, Kameka AM, Mehta R, Ivy GO, Ruehl WW, Milgram NW. The effects of L-deprenyl on spatial short term memory in young and aged dogs. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 20: 515-30. PMID 8771606 DOI: 10.1016/0278-5846(96)00014-0 |
0.393 |
|
1996 |
Cummings BJ, Head E, Ruehl W, Milgram NW, Cotman CW. The canine as an animal model of human aging and dementia. Neurobiology of Aging. 17: 259-68. PMID 8744407 DOI: 10.1016/0197-4580(95)02060-8 |
0.455 |
|
1996 |
Rick JT, Murphy MP, Ivy GO, Milgram NW. Short intertrial intervals impair water maze performance in old Fischer 344 rats. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 51: B253-60. PMID 8680989 DOI: 10.1093/Gerona/51A.4.B253 |
0.395 |
|
1996 |
Cummings BJ, Head E, Afagh AJ, Milgram NW, Cotman CW. Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine. Neurobiology of Learning and Memory. 66: 11-23. PMID 8661247 DOI: 10.1006/Nlme.1996.0039 |
0.383 |
|
1995 |
Ruehl WW, Bruyette DS, DePaoli A, Cotman CW, Head E, Milgram NW, Cummings BJ. Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to 1-deprenyl therapy. Progress in Brain Research. 106: 217-25. PMID 8584657 DOI: 10.1016/S0079-6123(08)61218-2 |
0.39 |
|
1995 |
Head E, Mehta R, Hartley J, Kameka M, Cummings BJ, Cotman CW, Ruehl WW, Milgram NW. Spatial learning and memory as a function of age in the dog. Behavioral Neuroscience. 109: 851-8. PMID 8554710 DOI: 10.1037//0735-7044.109.5.851 |
0.444 |
|
1995 |
Murphy MP, Rick JT, Milgram NW, Ivy GO. A simple and rapid test of sensorimotor function in the aged rat. Neurobiology of Learning and Memory. 64: 181-6. PMID 7582826 DOI: 10.1006/Nlme.1995.1057 |
0.362 |
|
1994 |
Milgram NW, Head E, Weiner E, Thomas E. Cognitive functions and aging in the dog: acquisition of nonspatial visual tasks. Behavioral Neuroscience. 108: 57-68. PMID 8192851 DOI: 10.1037//0735-7044.108.1.57 |
0.455 |
|
1994 |
Carrillo MC, Ivy GO, Milgram NW, Head E, Wu P, Kitani K. (-)Deprenyl increases activities of superoxide dismutase (SOD) in striatum of dog brain. Life Sciences. 54: 1483-9. PMID 8190023 DOI: 10.1016/0024-3205(94)90015-9 |
0.301 |
|
1994 |
Ivy GO, Rick JT, Murphy MP, Head E, Reid C, Milgram NW. Effects of L-deprenyl on manifestations of aging in the rat and dog. Annals of the New York Academy of Sciences. 717: 45-59. PMID 8030851 DOI: 10.1111/J.1749-6632.1994.Tb12072.X |
0.339 |
|
1993 |
Milgram NW, Ivy GO, Head E, Murphy MP, Wu PH, Ruehl WW, Yu PH, Durden DA, Davis BA, Paterson IA. The effect of L-deprenyl on behavior, cognitive function, and biogenic amines in the dog. Neurochemical Research. 18: 1211-9. PMID 8272186 DOI: 10.1007/Bf00975038 |
0.318 |
|
1990 |
Milgram NW, Racine RJ, Nellis P, Mendonca A, Ivy GO. Maintenance on L-deprenyl prolongs life in aged male rats. Life Sciences. 47: 415-20. PMID 2118586 DOI: 10.1016/0024-3205(90)90299-7 |
0.317 |
|
1985 |
Campbell KA, Milgram NW. Mechanisms underlying the plasticity of hippocampal stimulation-induced reward Behavioral Neuroscience. 99: 209-219. PMID 3843708 DOI: 10.1037//0735-7044.99.2.209 |
0.303 |
|
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