Raymond Chuen-Chung Chang, PhD - Publications

Anatomy The University of Hong Kong, San Francisco, Hong Kong Island, Hong Kong 
Neuroscience, neuroimmunology, neurodegeneration, Alzheimer's disease, Parkinson's disease, glaucoma, herbal medicine, depression, neuroinflammation

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ng LHL, Huang Y, Han L, Chang RC, Chan YS, Lai CSW. Ketamine and selective activation of parvalbumin interneurons inhibit stress-induced dendritic spine elimination. Translational Psychiatry. 8: 272. PMID 30531859 DOI: 10.1038/s41398-018-0321-5  0.6
2016 Yu SS, Tang X, Ho YS, Chang RC, Chiu K. Links between the Brain and Retina: The Effects of Cigarette Smoking-Induced Age-Related Changes in Alzheimer's Disease and Macular Degeneration. Frontiers in Neurology. 7: 119. PMID 27512384 DOI: 10.3389/fneur.2016.00119  0.6
2016 Lai HM, Liu AK, Ng WL, DeFelice J, Lee WS, Li H, Li W, Ng HM, Chang RC, Lin B, Wu W, Gentleman SM. Rationalisation and Validation of an Acrylamide-Free Procedure in Three-Dimensional Histological Imaging. Plos One. 11: e0158628. PMID 27359336 DOI: 10.1371/journal.pone.0158628  0.6
2016 Huang C, Ng OT, Ho YS, Irwin MG, Chang RC, Wong GT. Effect of Continuous Propofol Infusion to Rat on Tau Phosphorylation with or without Temperature Control. Journal of Alzheimer's Disease : Jad. PMID 26836157 DOI: 10.3233/JAD-150645  0.6
2015 Poon DC, Ho YS, You R, Tse HL, Chiu K, Chang RC. PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load. Journal of Neuroinflammation. 12: 212. PMID 26585788 DOI: 10.1186/s12974-015-0433-2  0.6
2015 Liu AK, Hurry ME, Ng OT, DeFelice J, Lai HM, Pearce RK, Wong GT, Chang RC, Gentleman SM. Bringing CLARITY to the human brain: visualisation of Lewy pathology in three-dimensions. Neuropathology and Applied Neurobiology. PMID 26526972 DOI: 10.1111/nan.12293  0.6
2015 Asthana P, Vong JS, Kumar G, Chang RC, Zhang G, Sheikh KA, Ma CH. Dissecting the Role of Anti-ganglioside Antibodies in Guillain-Barré Syndrome: an Animal Model Approach. Molecular Neurobiology. PMID 26374552 DOI: 10.1007/s12035-015-9430-9  0.6
2015 Zhang LQ, Sa F, Chong CM, Wang Y, Zhou ZY, Chang RC, Chan SW, Hoi PM, Yuen Lee SM. Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3β pathways. Journal of Ethnopharmacology. 170: 8-15. PMID 25934514 DOI: 10.1016/j.jep.2015.04.040  0.6
2015 Jiang T, Chang RC, Rosenmann H, Yu JT. Advances in Alzheimer's disease: from bench to bedside. Biomed Research International. 2015: 202676. PMID 25789309 DOI: 10.1155/2015/202676  0.6
2015 Carret-Rebillat AS, Pace C, Gourmaud S, Ravasi L, Montagne-Stora S, Longueville S, Tible M, Sudol E, Chang RC, Paquet C, Mouton-Liger F, Hugon J. Neuroinflammation and Aβ accumulation linked to systemic inflammation are decreased by genetic PKR down-regulation. Scientific Reports. 5: 8489. PMID 25687824 DOI: 10.1038/srep08489  0.6
2015 Liu AK, Chang RC, Pearce RK, Gentleman SM. Nucleus basalis of Meynert revisited: anatomy, history and differential involvement in Alzheimer's and Parkinson's disease. Acta Neuropathologica. 129: 527-40. PMID 25633602 DOI: 10.1007/s00401-015-1392-5  0.6
2015 Ho WL, Leung Y, Cheng SS, Lok CK, Ho YS, Baum L, Yang X, Chiu K, Chang RC. Investigating degeneration of the retina in young and aged tau P301L mice. Life Sciences. 124: 16-23. PMID 25592136 DOI: 10.1016/j.lfs.2014.12.019  0.6
2015 Huang C, Ho YS, Ng OT, Irwin MG, Chang RC, Wong GT. Dexmedetomidine directly increases tau phosphorylation. Journal of Alzheimer's Disease : Jad. 44: 839-50. PMID 25374108 DOI: 10.3233/JAD-142238  0.6
2015 Yu J, Luo X, Xu H, Ma Q, Yuan J, Li X, Chang RC, Qu Z, Huang X, Zhuang Z, Liu J, Yang X. Identification of the key molecules involved in chronic copper exposure-aggravated memory impairment in transgenic mice of Alzheimer's disease using proteomic analysis. Journal of Alzheimer's Disease : Jad. 44: 455-69. PMID 25352456 DOI: 10.3233/JAD-141776  0.6
2015 Wang H, Lau BWM, Wang NL, Wang SY, Lu QJ, Chang RCC, So KF. Lycium barbarum polysaccharides promotes in vivo proliferation of adult rat retinal progenitor cells Neural Regeneration Research. 10: 1976-1981. DOI: 10.4103/1673-5374.172315  0.6
2015 Sy LK, Lok CN, Wang JY, Liu Y, Cheng L, Wan PK, Leung CT, Cao B, Kwong WL, Chang RCC, Che CM. Identification of "sarsasapogenin-aglyconed" timosaponins as novel Aβ-lowering modulators of amyloid precursor protein processing Chemical Science. 7: 3206-3214. DOI: 10.1039/c5sc02377g  0.6
2015 Poon DCH, Ho YS, Chiu K, Wong HL, Chang RCC. Sickness: From the focus on cytokines, prostaglandins, and complement factors to the perspectives of neurons Neuroscience and Biobehavioral Reviews. 57: 30-45. DOI: 10.1016/j.neubiorev.2015.07.015  0.6
2015 Wui-Man Lau B, Chin-Pang Leung M, Po KT, Chang RCC, So KF. Prosexual effects of lycium barbarum Lycium Barbarum and Human Health. 113-123. DOI: 10.1007/978-94-017-9658-3_8  0.6
2015 Ho YS, Li XA, Hiu-Ling Hung C, Chang RCC. Prevention of neurodegeneration for alzheimer’s disease by lycium barbarum Lycium Barbarum and Human Health. 99-111. DOI: 10.1007/978-94-017-9658-3_7  0.6
2015 Mi XS, Huang RJ, Ding Y, Chang RCC, So KF. Effects of lycium barbarum on modulation of blood vessel and hemodynamics Lycium Barbarum and Human Health. 65-77. DOI: 10.1007/978-94-017-9658-3_4  0.6
2015 Li HY, Chan HH, Chu PH, Chang RCC, So KF. Secondary degeneration after partial optic nerve injury and possible neuroprotective effects of lycium barbarum (Wolfberry) Lycium Barbarum and Human Health. 135-151. DOI: 10.1007/978-94-017-9658-3_10  0.6
2015 Chang RCC, So KF. Lycium Barbarum and human health Lycium Barbarum and Human Health. 1-198. DOI: 10.1007/978-94-017-9658-3  0.6
2014 Lau CF, Ho YS, Hung CH, Wuwongse S, Poon CH, Chiu K, Yang X, Chu LW, Chang RC. Protective effects of testosterone on presynaptic terminals against oligomeric β-amyloid peptide in primary culture of hippocampal neurons. Biomed Research International. 2014: 103906. PMID 25045655 DOI: 10.1155/2014/103906  0.6
2014 Xiao J, Xing F, Huo J, Fung ML, Liong EC, Ching YP, Xu A, Chang RC, So KF, Tipoe GL. Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model. Scientific Reports. 4: 5587. PMID 24998389 DOI: 10.1038/srep05587  0.6
2014 He M, Pan H, Chang RC, So KF, Brecha NC, Pu M. Activation of the Nrf2/HO-1 antioxidant pathway contributes to the protective effects of Lycium barbarum polysaccharides in the rodent retina after ischemia-reperfusion-induced damage. Plos One. 9: e84800. PMID 24400114 DOI: 10.1371/journal.pone.0084800  0.6
2014 Chang RC, Ho YS, Wong S, Gentleman SM, Ng HK. Neuropathology of cigarette smoking. Acta Neuropathologica. 127: 53-69. PMID 24240736 DOI: 10.1007/s00401-013-1210-x  0.6
2014 Chiu PW, Mak HK, Yau KK, Chan Q, Chang RC, Chu LW. Metabolic changes in the anterior and posterior cingulate cortices of the normal aging brain: proton magnetic resonance spectroscopy study at 3 T. Age (Dordrecht, Netherlands). 36: 251-64. PMID 23709317 DOI: 10.1007/s11357-013-9545-8  0.6
2013 Xu M, Chen X, Gu Y, Peng T, Yang D, Chang RC, So KF, Liu K, Shen J. Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury. Journal of Ethnopharmacology. 150: 116-24. PMID 23973788 DOI: 10.1016/j.jep.2013.08.020  0.6
2013 Wuwongse S, Cheng SS, Wong GT, Hung CH, Zhang NQ, Ho YS, Law AC, Chang RC. Effects of corticosterone and amyloid-beta on proteins essential for synaptic function: implications for depression and Alzheimer's disease. Biochimica Et Biophysica Acta. 1832: 2245-56. PMID 23928361 DOI: 10.1016/j.bbadis.2013.07.022  0.6
2013 Li H, Liang Y, Chiu K, Yuan Q, Lin B, Chang RC, So KF. Lycium barbarum (wolfberry) reduces secondary degeneration and oxidative stress, and inhibits JNK pathway in retina after partial optic nerve transection. Plos One. 8: e68881. PMID 23894366 DOI: 10.1371/journal.pone.0068881  0.6
2013 Xiao J, Liong EC, Ching YP, Chang RC, Fung ML, Xu AM, So KF, Tipoe GL. Lycium barbarum polysaccharides protect rat liver from non-alcoholic steatohepatitis-induced injury. Nutrition & Diabetes. 3: e81. PMID 23877747 DOI: 10.1038/nutd.2013.22  0.6
2013 Mi XS, Zhong JX, Chang RC, So KF. Research advances on the usage of traditional Chinese medicine for neuroprotection in glaucoma. Journal of Integrative Medicine. 11: 233-40. PMID 23867241 DOI: 10.3736/jintegrmed2013037  0.6
2013 Xiao J, Guo R, Fung ML, Liong EC, Chang RC, Ching YP, Tipoe GL. Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy. Evidence-Based Complementary and Alternative Medicine : Ecam. 2013: 642920. PMID 23861709 DOI: 10.1155/2013/642920  0.6
2013 Sen A, Wang Y, Chiu K, Whiley L, Cowan D, Chang RC, Legido-Quigley C. Metabolic phenotype of the healthy rodent model using in-vial extraction of dried serum, urine, and cerebrospinal fluid spots. Analytical Chemistry. 85: 7257-63. PMID 23845063 DOI: 10.1021/ac401149w  0.6
2013 Zhang YK, Wang J, Liu L, Chang RC, So KF, Ju G. The effect of Lycium barbarum on spinal cord injury, particularly its relationship with M1 and M2 macrophage in rats. Bmc Complementary and Alternative Medicine. 13: 67. PMID 23517687 DOI: 10.1186/1472-6882-13-67  0.6
2013 Poon DC, Ho YS, Chiu K, Chang RC. Cytokines: how important are they in mediating sickness? Neuroscience and Biobehavioral Reviews. 37: 1-10. PMID 23153795 DOI: 10.1016/j.neubiorev.2012.11.001  0.6
2013 Wong GT, Chang RC, Law AC. A breach in the scaffold: the possible role of cytoskeleton dysfunction in the pathogenesis of major depression. Ageing Research Reviews. 12: 67-75. PMID 22995339 DOI: 10.1016/j.arr.2012.08.004  0.6
2013 Ho YS, Hung CHL, Chang RCC. Green Tea and Neurodegeneration in Alzheimer's Disease Tea in Health and Disease Prevention. 691-704. DOI: 10.1016/B978-0-12-384937-3.00058-6  0.6
2012 Mi XS, Chiu K, Van G, Leung JW, Lo AC, Chung SK, Chang RC, So KF. Effect of Lycium barbarum Polysaccharides on the expression of endothelin-1 and its receptors in an ocular hypertension model of rat glaucoma. Neural Regeneration Research. 7: 645-51. PMID 25745457 DOI: 10.3969/j.issn.1673-5374.2012.09.001  0.6
2012 Ho WL, Leung Y, Tsang AW, So KF, Chiu K, Chang RC. Review: tauopathy in the retina and optic nerve: does it shadow pathological changes in the brain? Molecular Vision. 18: 2700-10. PMID 23170062  0.6
2012 Zhang E, Yau SY, Lau BW, Ma H, Lee TM, Chang RC, So KF. Synaptic plasticity, but not hippocampal neurogenesis, mediated the counteractive effect of wolfberry on depression in rats(1). Cell Transplantation. 21: 2635-49. PMID 23127884 DOI: 10.3727/096368912X655181  0.6
2012 Mi XS, Feng Q, Lo AC, Chang RC, Lin B, Chung SK, So KF. Protection of retinal ganglion cells and retinal vasculature by Lycium barbarum polysaccharides in a mouse model of acute ocular hypertension. Plos One. 7: e45469. PMID 23094016 DOI: 10.1371/journal.pone.0045469  0.6
2012 Zhu Q, Zhang NQ, Lau CF, Chao J, Sun Z, Chang RC, Chen F, Wang M. In vitro attenuation of acrolein-induced toxicity by phloretin, a phenolic compound from apple. Food Chemistry. 135: 1762-8. PMID 22953919 DOI: 10.1016/j.foodchem.2012.06.053  0.6
2012 Chao J, Leung Y, Wang M, Chang RC. Nutraceuticals and their preventive or potential therapeutic value in Parkinson's disease. Nutrition Reviews. 70: 373-86. PMID 22747840 DOI: 10.1111/j.1753-4887.2012.00484.x  0.6
2012 Ho YS, Yang X, Yeung SC, Chiu K, Lau CF, Tsang AW, Mak JC, Chang RC. Cigarette smoking accelerated brain aging and induced pre-Alzheimer-like neuropathology in rats. Plos One. 7: e36752. PMID 22606286 DOI: 10.1371/journal.pone.0036752  0.6
2012 Lau BW, Lee JC, Li Y, Fung SM, Sang YH, Shen J, Chang RC, So KF. Polysaccharides from wolfberry prevents corticosterone-induced inhibition of sexual behavior and increases neurogenesis. Plos One. 7: e33374. PMID 22523540 DOI: 10.1371/journal.pone.0033374  0.6
2012 Yang D, Li SY, Yeung CM, Chang RC, So KF, Wong D, Lo AC. Lycium barbarum extracts protect the brain from blood-brain barrier disruption and cerebral edema in experimental stroke. Plos One. 7: e33596. PMID 22438957 DOI: 10.1371/journal.pone.0033596  0.6
2012 Chan TF, Chiu K, Lok CK, Lau HW, So KF, Chang RC. Morphometric analyses of retinal sections. Journal of Visualized Experiments : Jove. PMID 22370760 DOI: 10.3791/3377  0.6
2012 Yik SY, Yu MS, Ho YS, Lai CS, Cheung YT, So KF, Chang RC. Neuroprotective effects of minocycline on double-stranded RNA-induced neurotoxicity in cultured cortical neurons. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 18: 42-4. PMID 22311362  0.6
2012 Ho YS, Poon DC, Chan TF, Chang RC. From small to big molecules: how do we prevent and delay the progression of age-related neurodegeneration? Current Pharmaceutical Design. 18: 15-26. PMID 22211681 DOI: 10.2174/138161212798919039  0.6
2012 Xiao J, Liong EC, Ching YP, Chang RC, So KF, Fung ML, Tipoe GL. Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation. Journal of Ethnopharmacology. 139: 462-70. PMID 22138659 DOI: 10.1016/j.jep.2011.11.033  0.6
2012 Ho YS, Yang X, Lau JC, Hung CH, Wuwongse S, Zhang Q, Wang J, Baum L, So KF, Chang RC. Endoplasmic reticulum stress induces tau pathology and forms a vicious cycle: implication in Alzheimer's disease pathogenesis. Journal of Alzheimer's Disease : Jad. 28: 839-54. PMID 22101233 DOI: 10.3233/JAD-2011-111037  0.6
2012 Chiu K, Chan TF, Wu A, Leung IY, So KF, Chang RC. Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina? Age (Dordrecht, Netherlands). 34: 633-49. PMID 21559868 DOI: 10.1007/s11357-011-9260-2  0.6
2011 Ho YS, So KF, Chang RC. Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia. Chinese Medicine. 6: 15. PMID 21513513 DOI: 10.1186/1749-8546-6-15  0.6
2011 Li SY, Yang D, Yeung CM, Yu WY, Chang RC, So KF, Wong D, Lo AC. Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury. Plos One. 6: e16380. PMID 21298100 DOI: 10.1371/journal.pone.0016380  0.6
2011 Lau BW, Ren C, Yang J, Yan SW, Chang RC, Pu M, So KF. Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal mongolian gerbil (Meriones unguiculatus). Cell Transplantation. 20: 871-81. PMID 21054936 DOI: 10.3727/096368910X539065  0.6
2011 Cheung YT, Zhang NQ, Hung CH, Lai CS, Yu MS, So KF, Chang RC. Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight β-amyloid peptide. Journal of Cellular and Molecular Medicine. 15: 244-57. PMID 20015199 DOI: 10.1111/j.1582-4934.2009.00990.x  0.6
2011 Ho YS, Chiu K, Hung CHL, So KF, Chang RCC. Holistic approach versus scientific evidence, what do we know about anti-aging herbal medicine in aging-associated neurodegenerative diseases? Phytochemicals and Human Health: Pharmacological and Molecular Aspects - a Tribute to Late Professor Bimal Kumar Bachhawat. 157-186.  0.6
2011 Ckiu K, Liang YX, Chang RCC, So KF. Lycium barbarum L.: A neuroprotective drug for glaucoma Ophthalmology in China. 20: 21-27.  0.6
2010 Zheng ZP, Ma J, Cheng KW, Chao J, Zhu Q, Chang RC, Zhao M, Lin ZX, Wang M. Sulfur-containing constituents and one 1H-pyrrole-2-carboxylic acid derivative from pineapple [Ananas comosus (L.) Merr.] fruit. Phytochemistry. 71: 2046-51. PMID 20843530 DOI: 10.1016/j.phytochem.2010.08.014  0.6
2010 Hung CH, Ho YS, Chang RC. Modulation of mitochondrial calcium as a pharmacological target for Alzheimer's disease. Ageing Research Reviews. 9: 447-56. PMID 20553970 DOI: 10.1016/j.arr.2010.05.003  0.6
2010 Peng X, Ma J, Chao J, Sun Z, Chang RC, Tse I, Li ET, Chen F, Wang M. Beneficial effects of cinnamon proanthocyanidins on the formation of specific advanced glycation endproducts and methylglyoxal-induced impairment on glucose consumption. Journal of Agricultural and Food Chemistry. 58: 6692-6. PMID 20476737 DOI: 10.1021/jf100538t  0.6
2010 Wuwongse S, Chang RC, Law AC. The putative neurodegenerative links between depression and Alzheimer's disease. Progress in Neurobiology. 91: 362-75. PMID 20441786 DOI: 10.1016/j.pneurobio.2010.04.005  0.6
2010 Chiu K, Zhou Y, Yeung SC, Lok CK, Chan OO, Chang RC, So KF, Chiu JF. Up-regulation of crystallins is involved in the neuroprotective effect of wolfberry on survival of retinal ganglion cells in rat ocular hypertension model. Journal of Cellular Biochemistry. 110: 311-20. PMID 20336662 DOI: 10.1002/jcb.22539  0.6
2010 Ho YS, Yu MS, Yang XF, So KF, Yuen WH, Chang RC. Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons. Journal of Alzheimer's Disease : Jad. 19: 813-27. PMID 20157238 DOI: 10.3233/JAD-2010-1280  0.6
2010 Yu HT, Chan WW, Chai KH, Lee CW, Chang RC, Yu MS, McLoughlin DM, Miller CC, Lau KF. Transcriptional regulation of human FE65, a ligand of Alzheimer's disease amyloid precursor protein, by Sp1. Journal of Cellular Biochemistry. 109: 782-93. PMID 20091743 DOI: 10.1002/jcb.22457  0.6
2010 Chiu K, Yeung SC, So KF, Chang RC. Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma. Cellular & Molecular Immunology. 7: 61-8. PMID 20081877 DOI: 10.1038/cmi.2009.110  0.6
2010 Chao J, Lau WK, Huie MJ, Ho YS, Yu MS, Lai CS, Wang M, Yuen WH, Lam WH, Chan TH, Chang RC. A pro-drug of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) prevents differentiated SH-SY5Y cells from toxicity induced by 6-hydroxydopamine. Neuroscience Letters. 469: 360-4. PMID 20026175 DOI: 10.1016/j.neulet.2009.12.028  0.6
2010 Ho YS, So KF, Chang RC. Anti-aging herbal medicine--how and why can they be used in aging-associated neurodegenerative diseases? Ageing Research Reviews. 9: 354-62. PMID 19833234 DOI: 10.1016/j.arr.2009.10.001  0.6
2010 Chao J, Li H, Cheng KW, Yu MS, Chang RC, Wang M. Protective effects of pinostilbene, a resveratrol methylated derivative, against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells. The Journal of Nutritional Biochemistry. 21: 482-9. PMID 19443200 DOI: 10.1016/j.jnutbio.2009.02.004  0.6
2010 Cheung YT, Lau WKW, Chang RCC. What do we need to concern in using cell line for neurotoxicology research, differentiation or disturbance of intracellular signaling? Neurotoxicology. 31: 165-166. DOI: 10.1016/j.neuro.2009.10.016  0.6
2009 Chang RC, Chiu K, Ho YS, So KF. Modulation of neuroimmune responses on glia in the central nervous system: implication in therapeutic intervention against neuroinflammation. Cellular & Molecular Immunology. 6: 317-26. PMID 19887044 DOI: 10.1038/cmi.2009.42  0.6
2009 Hugon J, Paquet C, Chang RC. Could PKR inhibition modulate human neurodegeneration? Expert Review of Neurotherapeutics. 9: 1455-7. PMID 19831834 DOI: 10.1586/ern.09.92  0.6
2009 Chiu K, Chan HC, Yeung SC, Yuen WH, Zee SY, Chang RC, So KF. Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model. Journal of Ocular Biology, Diseases, and Informatics. 2: 47-56. PMID 19672466 DOI: 10.1007/s12177-009-9023-9  0.6
2009 Yu JT, Chang RC, Tan L. Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities. Progress in Neurobiology. 89: 240-55. PMID 19664678 DOI: 10.1016/j.pneurobio.2009.07.009  0.6
2009 Ho YS, Yu MS, Yik SY, So KF, Yuen WH, Chang RC. Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons. Cellular and Molecular Neurobiology. 29: 1233-44. PMID 19499323 DOI: 10.1007/s10571-009-9419-x  0.6
2009 Lai CS, Preisler J, Baum L, Lee DH, Ng HK, Hugon J, So KF, Chang RC. Low molecular weight Abeta induces collapse of endoplasmic reticulum. Molecular and Cellular Neurosciences. 41: 32-43. PMID 19386229 DOI: 10.1016/j.mcn.2009.01.006  0.6
2009 Albensi B, Breen G, Cashikar A, Chai X, Chang R, Cuellar T, Frederikse P, Hayashi M, Hebert S, Kinoshita J, Kosik K, Long J, Maloney B, Mizumoto L, Muresan V, et al. Alzheimer research forum live discussion: Non-coding RNAs in neurodegeneration Journal of Alzheimer's Disease. 16: 441-444. PMID 19221433 DOI: 10.3233/JAD-2009-1007  0.6
2009 Cheung YT, Lau WK, Yu MS, Lai CS, Yeung SC, So KF, Chang RC. Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research. Neurotoxicology. 30: 127-35. PMID 19056420 DOI: 10.1016/j.neuro.2008.11.001  0.6
2008 Chiu K, Lau WM, Yeung SC, Chang RC, So KF. Retrograde labeling of retinal ganglion cells by application of fluoro-gold on the surface of superior colliculus. Journal of Visualized Experiments : Jove. PMID 19066544 DOI: 10.3791/819  0.6
2008 Lau KF, Chan WM, Perkinton MS, Tudor EL, Chang RC, Chan HY, McLoughlin DM, Miller CC. Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription. The Journal of Biological Chemistry. 283: 34728-37. PMID 18922798 DOI: 10.1074/jbc.M801874200  0.6
2008 Chao J, Yu MS, Ho YS, Wang M, Chang RC. Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity. Free Radical Biology & Medicine. 45: 1019-26. PMID 18675900 DOI: 10.1016/j.freeradbiomed.2008.07.002  0.6
2008 Lai CS, Yu MS, Yuen WH, So KF, Zee SY, Chang RC. Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum. Brain Research. 1190: 215-24. PMID 18083148 DOI: 10.1016/j.brainres.2007.10.103  0.6
2008 Chang RC, So KF. Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far? Cellular and Molecular Neurobiology. 28: 643-52. PMID 17710531 DOI: 10.1007/s10571-007-9181-x  0.6
2008 Mok P, Chang RCC, Wang M, So KF. A review on the laboratory investigations and epidemiological studies of black and pu-Erh tea Acs Symposium Series. 987: 144-159. DOI: 10.1021/bk-2008-0987.ch009  0.6
2008 Sze SCW, Song J, Chang RCC, Zhang KY, Wong RNS, Tong Y. Research advances on the anti-aging profile of Fructus lycii: An ancient Chinese herbal medicine Journal of Complementary and Integrative Medicine. 5.  0.6
2007 Chiu K, Lau WM, Lau HT, So KF, Chang RC. Micro-dissection of rat brain for RNA or protein extraction from specific brain region. Journal of Visualized Experiments : Jove. 269. PMID 18989440 DOI: 10.3791/269  0.6
2007 Chiu K, Chang RC, So KF. Intravitreous injection for establishing ocular diseases model. Journal of Visualized Experiments : Jove. 313. PMID 18989417 DOI: 10.3791/313  0.6
2007 Chiu K, Chang R, So KF. Laser-induced chronic ocular hypertension model on SD rats. Journal of Visualized Experiments : Jove. 549. PMID 18989402 DOI: 10.3791/549  0.6
2007 Yu MS, Lai CS, Ho YS, Zee SY, So KF, Yuen WH, Chang RC. Characterization of the effects of anti-aging medicine Fructus lycii on beta-amyloid peptide neurotoxicity. International Journal of Molecular Medicine. 20: 261-8. PMID 17611646  0.6
2007 Ho YS, Yu MS, Lai CS, So KF, Yuen WH, Chang RC. Characterizing the neuroprotective effects of alkaline extract of Lycium barbarum on beta-amyloid peptide neurotoxicity. Brain Research. 1158: 123-34. PMID 17568570 DOI: 10.1016/j.brainres.2007.04.075  0.6
2007 Yu MS, Wong AY, So KF, Fang JN, Yuen WH, Chang RC. New polysaccharide from Nerium indicum protects neurons via stress kinase signaling pathway. Brain Research. 1153: 221-30. PMID 17475226 DOI: 10.1016/j.brainres.2007.03.074  0.6
2007 Chan HC, Chang RC, Koon-Ching Ip A, Chiu K, Yuen WH, Zee SY, So KF. Neuroprotective effects of Lycium barbarum Lynn on protecting retinal ganglion cells in an ocular hypertension model of glaucoma. Experimental Neurology. 203: 269-73. PMID 17045262 DOI: 10.1016/j.expneurol.2006.05.031  0.6
2006 Chang RC, Yu MS, Lai CS. Significance of molecular signaling for protein translation control in neurodegenerative diseases. Neuro-Signals. 15: 249-58. PMID 17496426 DOI: 10.1159/000102599  0.6
2006 Yu MS, Ho YS, So KF, Yuen WH, Chang RC. Cytoprotective effects of Lycium barbarum against reducing stress on endoplasmic reticulum. International Journal of Molecular Medicine. 17: 1157-61. PMID 16685430  0.6
2006 Yu MS, Suen KC, Kwok NS, So KF, Hugon J, Chang RC. Beta-amyloid peptides induces neuronal apoptosis via a mechanism independent of unfolded protein responses. Apoptosis : An International Journal On Programmed Cell Death. 11: 687-700. PMID 16532272 DOI: 10.1007/s10495-006-5540-1  0.6
2006 Lai SW, Yu MS, Yuen WH, Chang RC. Novel neuroprotective effects of the aqueous extracts from Verbena officinalis Linn. Neuropharmacology. 50: 641-50. PMID 16406021 DOI: 10.1016/j.neuropharm.2005.11.009  0.6
2005 Fang X, Yu MM, Yuen WH, Zee SY, Chang RC. Immune modulatory effects of Prunella vulgaris L. on monocytes/macrophages. International Journal of Molecular Medicine. 16: 1109-16. PMID 16273294  0.6
2005 Yu MS, Leung SK, Lai SW, Che CM, Zee SY, So KF, Yuen WH, Chang RC. Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity. Experimental Gerontology. 40: 716-27. PMID 16139464 DOI: 10.1016/j.exger.2005.06.010  0.6
2005 Wong HL, Wang X, Chang RCC, Jin DY, Feng H, Wang Q, Lo KW, Huang DP, Yuen PW, Takada K, Wong YC, Tsao SW. Stable expression of EBERs in immortalized nasopharyngeal epithelial cells confers resistance to apoptotic stress Molecular Carcinogenesis. 44: 92-101. PMID 16086371 DOI: 10.1002/mc.20133  0.6
2004 Lin KF, Chang RC, Suen KC, So KF, Hugon J. Modulation of calcium/calmodulin kinase-II provides partial neuroprotection against beta-amyloid peptide toxicity. The European Journal of Neuroscience. 19: 2047-55. PMID 15090032 DOI: 10.1111/j.0953-816X.2004.03245.x  0.6
2003 Suen KC, Lin KF, Elyaman W, So KF, Chang RC, Hugon J. Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity. Journal of Neurochemistry. 87: 1413-26. PMID 14713297 DOI: 10.1111/j.1471-4159.2003.02259.x  0.6
2003 Suen KC, Yu MS, So KF, Chang RC, Hugon J. Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity. The Journal of Biological Chemistry. 278: 49819-27. PMID 12975376 DOI: 10.1074/jbc.M306503200  0.6
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