Jack T. Stapleton - Publications

Affiliations: 
Molecular & Cell Biology University of Iowa, Iowa City, IA 
Area:
Virology Biology, Immunology, Cell Biology

145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mishra T, Phillips S, Maldonado C, Stapleton JT, Wu L. Antiretroviral Therapy Suppresses RNA -Methyladenosine Modification in Peripheral Blood Mononuclear Cells from HIV-1-Infected Individuals. Aids Research and Human Retroviruses. PMID 38753726 DOI: 10.1089/AID.2024.0003  0.353
2022 Stapleton JT. Human Pegivirus Type 1: A Common Human Virus That Is Beneficial in Immune-Mediated Disease? Frontiers in Immunology. 13: 887760. PMID 35707535 DOI: 10.3389/fimmu.2022.887760  0.471
2021 Colon-Moran W, Baer A, Lamture G, Stapleton JT, Fischer JW, Bhattarai N. A short hepatitis C virus NS5A peptide expression by AAV vector modulates human T cell activation and reduces vector immunogenicity. Gene Therapy. PMID 34759330 DOI: 10.1038/s41434-021-00302-5  0.565
2020 Kaddour H, Lyu Y, Welch JL, Paromov V, Mandape SN, Sakhare SS, Pandhare J, Stapleton JT, Pratap S, Dash C, Okeoma CM. Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities. Molecular & Cellular Proteomics : McP. 19: 78-100. PMID 33451560 DOI: 10.1074/mcp.RA119.001594  0.331
2020 Kaddour H, Panzner TD, Welch JL, Shouman N, Mohan M, Stapleton JT, Okeoma CM. Electrostatic Surface Properties of Blood and Semen Extracellular Vesicles: Implications of Sialylation and HIV-Induced Changes on EV Internalization. Viruses. 12. PMID 33019624 DOI: 10.3390/v12101117  0.339
2020 Welch JL, Xiang J, Okeoma CM, Schlievert PM, Stapleton JT. Glycerol Monolaurate, an Analogue to a Factor Secreted by , Is Virucidal against Enveloped Viruses, Including HIV-1. Mbio. 11. PMID 32371599 DOI: 10.1128/Mbio.00686-20  0.52
2020 Welch JL, Kaddour H, Winchester L, Fletcher CV, Stapleton JT, Okeoma CM. Semen Extracellular Vesicles From HIV-1-Infected Individuals Inhibit HIV-1 Replication In Vitro, and Extracellular Vesicles Carry Antiretroviral Drugs In Vivo. Journal of Acquired Immune Deficiency Syndromes (1999). 83: 90-98. PMID 31809364 DOI: 10.1097/Qai.0000000000002233  0.49
2019 Kaddour H, Lyu Y, Welch JL, Paromov V, Mandape SN, Sakhare SS, Pandhare J, Stapleton JT, Pratap S, Dash C, Okeoma CM. Proteomics profiling of autologous blood and semen exosomes from HIV-infected and uninfected individuals reveals compositional and functional variabilities. Molecular & Cellular Proteomics : McP. PMID 31676584 DOI: 10.1074/Mcp.Ra119.001594  0.438
2019 Fama A, Larson MC, Link BK, Habermann TM, Feldman AL, Call TG, Ansell SM, Liebow M, Xiang J, Maurer MJ, Slager SL, Nowakowski GS, Stapleton JT, Cerhan JR. Human Pegivirus Infection and Lymphoma Risk: A Systematic Review and Meta-analysis. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 31671178 DOI: 10.1093/Cid/Ciz940  0.356
2019 Welch JL, Kaufman TM, Stapleton JT, Okeoma CM. Semen exosomes inhibit HIV infection and HIV-induced proinflammatory cytokine production independently of the activation state of primary lymphocytes. Febs Letters. PMID 31665815 DOI: 10.1002/1873-3468.13653  0.504
2019 Lyu Y, Kaddour H, Kopcho S, Panzner TD, Shouman N, Kim EY, Martinson J, McKay H, Martinez-Maza O, Margolick JB, Stapleton JT, Okeoma CM. Human Immunodeficiency Virus (HIV) Infection and Use of Illicit Substances Promote Secretion of Semen Exosomes that Enhance Monocyte Adhesion and Induce Actin Reorganization and Chemotactic Migration. Cells. 8. PMID 31484431 DOI: 10.3390/Cells8091027  0.475
2019 Welch JL, Stapleton JT, Okeoma CM. Vehicles of intercellular communication: exosomes and HIV-1. The Journal of General Virology. PMID 30702421 DOI: 10.1099/Jgv.0.001193  0.448
2018 Welch JL, Kaddour H, Schlievert PM, Stapleton JT, Okeoma CM. Semen exosomes promote transcriptional silencing of HIV-1 by disrupting NF-kB/Sp1/Tat circuitry. Journal of Virology. PMID 30111566 DOI: 10.1128/Jvi.00731-18  0.472
2017 Siewe B, Nipper AJ, Sohn H, Stapleton JT, Landay A. FcRL4 Expression Identifies a Pro-inflammatory B Cell Subset in Viremic HIV-Infected Subjects. Frontiers in Immunology. 8: 1339. PMID 29104574 DOI: 10.3389/Fimmu.2017.01339  0.374
2017 Malherbe DC, Mendy J, Vang L, Barnette PT, Reed J, Lakhashe SK, Owuor J, Gach JS, Legasse AW, Axthelm MK, LaBranche CC, Montefiori D, Forthal DN, Park B, Wilson JM, ... ... Stapleton JT, et al. Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C SHIV Mucosal Challenge. Journal of Virology. PMID 29093095 DOI: 10.1128/Jvi.01092-17  0.399
2017 Baer A, Colon-Moran W, Xiang J, Stapleton JT, Bhattarai N. Src-family kinases negatively regulate NFAT signaling in resting human T cells. Plos One. 12: e0187123. PMID 29073235 DOI: 10.1371/Journal.Pone.0187123  0.565
2017 McLinden JH, Bhattarai N, Stapleton JT, Chang Q, Kaufman TM, Cassel SL, Sutterwala FS, Haim H, Houtman J, Xiang J. Yellow fever virus, but not Zika or Dengue virus inhibits T cell receptor-mediated T cell function by an RNA-based mechanism. The Journal of Infectious Diseases. PMID 28968905 DOI: 10.1093/Infdis/Jix462  0.641
2017 Smith DB, Meyers G, Bukh J, Gould EA, Monath T, Scott Muerhoff A, Pletnev A, Rico-Hesse R, Stapleton JT, Simmonds P, Becher P. Proposed revision to the taxonomy of the genus Pestivirus, family Flaviviridae. The Journal of General Virology. PMID 28786787 DOI: 10.1099/Jgv.0.000873  0.343
2017 DeLeon O, Hodis H, O'Malley Y, Johnson J, Salimi H, Zhai Y, Winter E, Remec C, Eichelberger N, Van Cleave B, Puliadi R, Harrington RD, Stapleton JT, Haim H. Accurate predictions of population-level changes in sequence and structural properties of HIV-1 Env using a volatility-controlled diffusion model. Plos Biology. 15: e2001549. PMID 28384158 DOI: 10.1371/Journal.Pbio.2001549  0.324
2017 Bhattarai N, McLinden JH, Xiang J, Mathahs MM, Schmidt WN, Kaufman TM, Stapleton JT. Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo. Plos Pathogens. 13: e1006232. PMID 28235043 DOI: 10.1371/Journal.Ppat.1006232  0.627
2017 Simmonds P, Becher P, Bukh J, Gould EA, Meyers G, Monath T, Muerhoff S, Pletnev A, Rico-Hesse R, Smith DB, Stapleton JT, Ictv Report Consortium. ICTV Virus Taxonomy Profile: Flaviviridae. The Journal of General Virology. 98: 2-3. PMID 28218572 DOI: 10.1099/Jgv.0.000672  0.41
2017 Fama A, Xiang J, Allmer C, Link BK, Klinzman D, Feldman AL, Nowakowski GS, Liebow M, Larson MC, Maurer MJ, Slager SL, Call TG, Ansell SM, Novak AJ, Habermann TM, ... ... Stapleton JT, et al. Human Pegivirus (HPgV) Infection and Lymphoma Risk and Prognosis: A Study from North America Blood. 130: 2773-2773. DOI: 10.1182/Blood.V130.Suppl_1.2773.2773  0.313
2017 Fama A, Allmer C, Link B, Xiang J, Klinzman D, Feldman A, Nowakowski G, Liebow M, Larson M, Slager S, Call T, Habermann T, Cerhan J, Stapleton J. GB VIRUS-C (GBV-C) INFECTION AND RISK OF LYMPHOMA: A CASE-CONTROL STUDY FROM NORTH AMERICA Hematological Oncology. 35: 55-56. DOI: 10.1002/Hon.2437_40  0.431
2016 Gajurel K, Stapleton JT. Hepatitis Viruses in Kidney Transplantation. Seminars in Nephrology. 36: 386-396. PMID 27772623 DOI: 10.1016/J.Semnephrol.2016.05.015  0.322
2016 Smith DB, Becher P, Bukh J, Gould EA, Meyers G, Monath T, Muerhoff AS, Pletnev A, Rico-Hesse R, Stapleton JT, Simmonds P. Proposed update to the taxonomy of the genera Hepacivirus and Pegivirus within the Flaviviridae family. The Journal of General Virology. PMID 27692039 DOI: 10.1099/Jgv.0.000612  0.321
2015 Dogan MV, Xiang J, Beach SR, Cutrona C, Gibbons FX, Simons RL, Brody GH, Stapleton JT, Philibert RA. Ethnicity and Smoking-Associated DNA Methylation Changes at HIV Co-Receptor GPR15. Frontiers in Psychiatry. 6: 132. PMID 26441693 DOI: 10.3389/Fpsyt.2015.00132  0.35
2015 Bhattarai N, McLinden JH, Xiang J, Kaufman TM, Stapleton JT. Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation. Plos Pathogens. 11: e1005183. PMID 26421924 DOI: 10.1371/Journal.Ppat.1005183  0.611
2015 Overton ET, Stapleton J, Frank I, Hassler S, Goepfert PA, Barker D, Wagner E, von Krempelhuber A, Virgin G, Meyer TP, Müller J, Bädeker N, Grünert R, Young P, Rösch S, et al. Safety and Immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic Smallpox Vaccine in Vaccinia-Naive and Experienced Human Immunodeficiency Virus-Infected Individuals: An Open-Label, Controlled Clinical Phase II Trial. Open Forum Infectious Diseases. 2: ofv040. PMID 26380340 DOI: 10.1093/Ofid/Ofv040  0.456
2015 Chivero ET, Bhattarai N, McLinden JH, Xiang J, Stapleton JT. Human Pegivirus (HPgV; formerly known as GBV-C) inhibits IL-12 dependent natural killer cell function. Virology. 485: 116-127. PMID 26245365 DOI: 10.1016/J.Virol.2015.07.008  0.684
2015 Chastain CA, Beekmann SE, Wallender EK, Hulgan T, Stapleton JT, Polgreen PM. Hepatitis C Management and the Infectious Diseases Physician: A Survey of Current and Anticipated Practice Patterns. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 61: 792-4. PMID 25979310 DOI: 10.1093/Cid/Civ384  0.335
2015 Chivero ET, Stapleton JT. Tropism of human pegivirus (formerly known as GB virus C/hepatitis G virus) and host immunomodulation: insights into a highly successful viral infection. The Journal of General Virology. 96: 1521-32. PMID 25667328 DOI: 10.1099/Vir.0.000086  0.457
2015 Lanteri MC, Vahidnia F, Tan S, Stapleton JT, Norris PJ, Heitman J, Deng X, Keating SM, Brambilla D, Busch MP, Custer B. Downregulation of Cytokines and Chemokines by GB Virus C After Transmission Via Blood Transfusion in HIV-Positive Blood Recipients. The Journal of Infectious Diseases. 211: 1585-96. PMID 25425697 DOI: 10.1093/Infdis/Jiu660  0.591
2015 Chivero ET, Bhattarai N, McLinden JH, Xiang J, Stapleton JT. Human Pegivirus (HPgV; formerly known as GBV-C) inhibits IL-12 dependent natural killer cell function Virology. 485: 116-127. DOI: 10.1016/j.virol.2015.07.008  0.534
2014 Stapleton JT, Xiang J, McLinden JH, Bhattarai N, Chivero ET, Klinzman D, Kaufman TM, Chang Q. A novel T cell evasion mechanism in persistent RNA virus infection. Transactions of the American Clinical and Climatological Association. 125: 14-24; discussion 24. PMID 25125715  0.632
2014 Chang CM, Stapleton JT, Klinzman D, McLinden JH, Purdue MP, Katki HA, Engels EA. GBV-C infection and risk of NHL among U.S. adults. Cancer Research. 74: 5553-60. PMID 25115299 DOI: 10.1158/0008-5472.Can-14-0209  0.416
2014 Siewe B, Wallace J, Rygielski S, Stapleton JT, Martin J, Deeks SG, Landay A. Regulatory B cells inhibit cytotoxic T lymphocyte (CTL) activity and elimination of infected CD4 T cells after in vitro reactivation of HIV latent reservoirs. Plos One. 9: e92934. PMID 24739950 DOI: 10.1371/Journal.Pone.0092934  0.464
2014 Chivero ET, Bhattarai N, Rydze RT, Winters MA, Holodniy M, Stapleton JT. Human pegivirus RNA is found in multiple blood mononuclear cells in vivo and serum-derived viral RNA-containing particles are infectious in vitro. The Journal of General Virology. 95: 1307-19. PMID 24668525 DOI: 10.1099/Vir.0.063016-0  0.606
2014 Sahni H, Kirkwood K, Kyriakides TC, Stapleton J, Brown ST, Holodniy M. GBV-C viremia and clinical events in advanced HIV infection. Journal of Medical Virology. 86: 426-32. PMID 24249700 DOI: 10.1002/Jmv.23845  0.531
2014 Smith DB, Bukh J, Kuiken C, Muerhoff AS, Rice CM, Stapleton JT, Simmonds P. Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource. Hepatology (Baltimore, Md.). 59: 318-27. PMID 24115039 DOI: 10.1002/Hep.26744  0.321
2014 Lanteri M, Vahidnia F, Tan S, Stapleton J, Norris PJ, Heitman JW, Deng X, Keating S, Brambilla D, Busch M, Custer B. Downregulation of Cytokines and Chemokines By GB Virus C after Transfusion-Transmission in HIV+ Blood Recipients Blood. 124: 4122-4122. DOI: 10.1182/Blood.V124.21.4122.4122  0.552
2014 Chastain C, Beekmann SE, Wallender E, Hulgan T, Stapleton J, Polgreen PM. 741Management of Hepatitis C Among Infectious Diseases Physicians: Current Practice and Opinions Open Forum Infectious Diseases. 1: S209-S209. DOI: 10.1093/Ofid/Ofu052.449  0.314
2013 Stapleton JT, Martinson JA, Klinzman D, Xiang J, Desai SN, Landay A. GB virus C infection and B-cell, natural killer cell, and monocyte activation markers in HIV-infected individuals. Aids (London, England). 27: 1829-32. PMID 23807277 DOI: 10.1097/Qad.0B013E328363089F  0.568
2013 Bhattarai N, McLinden JH, Xiang J, Landay AL, Chivero ET, Stapleton JT. GB virus C particles inhibit T cell activation via envelope E2 protein-mediated inhibition of TCR signaling. Journal of Immunology (Baltimore, Md. : 1950). 190: 6351-9. PMID 23686495 DOI: 10.4049/Jimmunol.1300589  0.706
2013 Siewe B, Stapleton JT, Martinson J, Keshavarzian A, Kazmi N, Demarais PM, French AL, Landay A. Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8⁺ T cell function in vitro. Journal of Leukocyte Biology. 93: 811-8. PMID 23434518 DOI: 10.1189/Jlb.0912436  0.453
2013 McLinden JH, Stapleton JT, Klinzman D, Murthy KK, Chang Q, Kaufman TM, Bhattarai N, Xiang J. Chimpanzee GB virus C and GB virus A E2 envelope glycoproteins contain a peptide motif that inhibits human immunodeficiency virus type 1 replication in human CD4⁺ T-cells. The Journal of General Virology. 94: 774-82. PMID 23288422 DOI: 10.1099/Vir.0.047126-0  0.716
2013 Chang C, Stapleton J, Klinzman D, Larson L, Katki H, Purdue M, Engels EA. Abstract 2538: GB virus C viremia and subsequent risk of non-Hodgkin lymphoma in the PLCO screening trial. Cancer Research. 73: 2538-2538. DOI: 10.1158/1538-7445.Am2013-2538  0.423
2012 Stapleton JT, Chaloner K, Martenson JA, Zhang J, Klinzman D, Xiang J, Sauter W, Desai SN, Landay A. GB virus C infection is associated with altered lymphocyte subset distribution and reduced T cell activation and proliferation in HIV-infected individuals. Plos One. 7: e50563. PMID 23209780 DOI: 10.1371/Journal.Pone.0050563  0.53
2012 Rydze RT, Bhattarai N, Stapleton JT. GB virus C infection is associated with a reduced rate of reactivation of latent HIV and protection against activation-induced T-cell death. Antiviral Therapy. 17: 1271-9. PMID 22951385 DOI: 10.3851/Imp2309  0.715
2012 Bhattarai N, Rydze RT, Chivero ET, Stapleton JT. GB virus C viremia is associated with higher levels of double-negative T cells and lower T-cell activation in HIV-infected individuals receiving antiretroviral therapy. The Journal of Infectious Diseases. 206: 1469-72. PMID 22927453 DOI: 10.1093/Infdis/Jis515  0.7
2012 Bhattarai N, McLinden JH, Xiang J, Kaufman TM, Stapleton JT. GB virus C envelope protein E2 inhibits TCR-induced IL-2 production and alters IL-2-signaling pathways. Journal of Immunology (Baltimore, Md. : 1950). 189: 2211-6. PMID 22844114 DOI: 10.4049/Jimmunol.1201324  0.612
2012 Vahidnia F, Petersen M, Stapleton JT, Rutherford GW, Busch M, Custer B. Acquisition of GB virus type C and lower mortality in patients with advanced HIV disease. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 55: 1012-9. PMID 22752515 DOI: 10.1093/Cid/Cis589  0.555
2012 Bhattarai N, Stapleton JT. Study design may explain discrepancies in GB virus C effects on interferon-γ and interleukin-2 production and CD38 expression in T lymphocytes. MemóRias Do Instituto Oswaldo Cruz. 107: 568-9; author reply . PMID 22666874 DOI: 10.1590/S0074-02762012000400023  0.611
2012 Xiang J, McLinden JH, Kaufman TM, Mohr EL, Bhattarai N, Chang Q, Stapleton JT. Characterization of a peptide domain within the GB virus C envelope glycoprotein (E2) that inhibits HIV replication. Virology. 430: 53-62. PMID 22608061 DOI: 10.1016/J.Virol.2012.04.019  0.804
2012 Rydze RT, Xiang J, McLinden JH, Stapleton JT. GB virus type C infection polarizes T-cell cytokine gene expression toward a Th1 cytokine profile via NS5A protein expression. The Journal of Infectious Diseases. 206: 69-72. PMID 22535999 DOI: 10.1093/infdis/jis312  0.415
2012 Vahidnia F, Petersen M, Rutherford G, Busch M, Assmann S, Stapleton JT, Custer B. Transmission of GB virus type C via transfusion in a cohort of HIV-infected patients Journal of Infectious Diseases. 205: 1436-1442. PMID 22438325 DOI: 10.1093/Infdis/Jis209  0.53
2012 Bhattarai N, Stapleton JT. GB virus C: the good boy virus? Trends in Microbiology. 20: 124-30. PMID 22325031 DOI: 10.1016/J.Tim.2012.01.004  0.731
2012 Stapleton JT, Smith DB, Simmonds P. Evidence against GB virus C infection in dromedary camels. Veterinary Microbiology. 154: 403-6. PMID 21757300 DOI: 10.1016/J.Vetmic.2011.06.017  0.418
2011 Goldblatt D, Plikaytis BD, Akkoyunlu M, Antonello J, Ashton L, Blake M, Burton R, Care R, Durant N, Feavers I, Fernsten P, Fievet F, Giardina P, Jansen K, Katz L, ... ... Stapleton J, et al. Establishment of a new human pneumococcal standard reference serum, 007sp. Clinical and Vaccine Immunology : Cvi. 18: 1728-36. PMID 21852547 DOI: 10.1128/Cvi.05252-11  0.342
2011 Stapleton JT, Foung S, Muerhoff AS, Bukh J, Simmonds P. The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae. The Journal of General Virology. 92: 233-46. PMID 21084497 DOI: 10.1099/Vir.0.027490-0  0.402
2011 Mohr EL, Murthy KK, McLinden JH, Xiang J, Stapleton JT. The natural history of non-human GB virus C in captive chimpanzees. The Journal of General Virology. 92: 91-100. PMID 20861317 DOI: 10.1099/Vir.0.026088-0  0.757
2011 Boodram B, Hershow RC, Klinzman D, Stapleton JT. GB virus C infection among young, HIV-negative injection drug users with and without hepatitis C virus infection Journal of Viral Hepatitis. 18. PMID 20738773 DOI: 10.1111/J.1365-2893.2010.01350.X  0.434
2010 Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, ... ... Stapleton JT, et al. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science (New York, N.Y.). 330: 1551-7. PMID 21051598 DOI: 10.1126/Science.1195271  0.389
2010 Mohr EL, Xiang J, McLinden JH, Kaufman TM, Chang Q, Montefiori DC, Klinzman D, Stapleton JT. GB virus type C envelope protein E2 elicits antibodies that react with a cellular antigen on HIV-1 particles and neutralize diverse HIV-1 isolates. Journal of Immunology (Baltimore, Md. : 1950). 185: 4496-505. PMID 20826757 DOI: 10.4049/Jimmunol.1001980  0.771
2010 Stapleton JT, Chaloner K. GB virus C infection and non-Hodgkin lymphoma: important to know but the jury is out. International Journal of Cancer. Journal International Du Cancer. 126: 2759-61. PMID 20235124 DOI: 10.1002/Ijc.25194  0.447
2010 Zhang S, Zhang Y, Chaloner K, Stapleton JT. A copula model for bivariate hybrid censored survival data with application to the MACS study. Lifetime Data Analysis. 16: 231-49. PMID 19921432 DOI: 10.1007/S10985-009-9139-Z  0.486
2010 Vahidnia F, Petersen M, Rutherford G, Busch M, Assmann S, Stapleton J, Custer B. Transfusion Transmission of GB Virus Type C (HGV) In a Cohort of HIV Infected Patients Blood. 116: 3341-3341. DOI: 10.1182/Blood.V116.21.3341.3341  0.499
2009 Xiang J, McLinden JH, Rydze RA, Chang Q, Kaufman TM, Klinzman D, Stapleton JT. Viruses within the Flaviviridae decrease CD4 expression and inhibit HIV replication in human CD4+ cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 7860-9. PMID 19923460 DOI: 10.4049/Jimmunol.0902276  0.536
2009 Mohr EL, Stapleton JT. GB virus type C interactions with HIV: the role of envelope glycoproteins. Journal of Viral Hepatitis. 16: 757-68. PMID 19758271 DOI: 10.1111/J.1365-2893.2009.01194.X  0.788
2009 Stapleton JT. Comment on: GB virus infection: a silent anti-HIV panacea within? Transactions of the Royal Society of Tropical Medicine and Hygiene. 103: 1291-2; author reply. PMID 19576606 DOI: 10.1016/J.Trstmh.2009.05.011  0.515
2009 Stapleton JT, Chaloner K, Zhang J, Klinzman D, Souza IE, Xiang J, Landay A, Fahey J, Pollard R, Mitsuyasu R. GBV-C viremia is associated with reduced CD4 expansion in HIV-infected people receiving HAART and interleukin-2 therapy. Aids (London, England). 23: 605-10. PMID 19194270 DOI: 10.1097/Qad.0B013E32831F1B00  0.466
2008 Blankson JN, Klinzman D, Astemborski J, Thomas DL, Kirk GD, Stapleton JT. Low frequency of GB virus C viremia in a cohort of HIV-1-infected elite suppressors. Aids (London, England). 22: 2398-400. PMID 18981782 DOI: 10.1097/Qad.0B013E328316C3Fb  0.457
2008 Stapleton JT, Balfour HH. Coinfection alters the playing field: herpesviruses induce acyclovir to inhibit HIV. Cell Host & Microbe. 4: 194-5. PMID 18779044 DOI: 10.1016/J.Chom.2008.08.006  0.458
2008 McLinden JH, Stapleton JT, Chang Q, Xiang J. Expression of the dengue virus type 2 NS5 protein in a CD4(+) T cell line inhibits HIV replication. The Journal of Infectious Diseases. 198: 860-3. PMID 18721058 DOI: 10.1086/591254  0.546
2008 Xiang J, McLinden JH, Chang Q, Jordan EL, Stapleton JT. Characterization of a peptide domain within the GB virus C NS5A phosphoprotein that inhibits HIV replication. Plos One. 3: e2580. PMID 18596910 DOI: 10.1371/Journal.Pone.0002580  0.508
2008 Graziano FM, Kettoola SY, Munshower JM, Stapleton JT, Towfic GJ. Effect of spatial distribution of T-Cells and HIV load on HIV progression. Bioinformatics (Oxford, England). 24: 855-60. PMID 18187444 DOI: 10.1093/Bioinformatics/Btn008  0.359
2008 Stapleton J. A new variable influencing HCV-related liver disease in HIV-HCV coinfected individuals? Gastroenterology. 133: 2042-5. PMID 18054575 DOI: 10.1053/J.Gastro.2007.10.032  0.377
2008 Zhang W, Chaloner K, Cowles MK, Zhang Y, Stapleton JT. A Bayesian analysis of doubly censored data using a hierarchical Cox model. Statistics in Medicine. 27: 529-42. PMID 17694594 DOI: 10.1002/Sim.3002  0.455
2007 Stapleton JT, Bennett K, Bosch RJ, Polgreen PM, Swindells S. Effect of antiretroviral therapy and hepatitis C co-infection on changes in lipid levels in HIV-infected patients 48 weeks after initiation of therapy Hiv Clinical Trials. 8: 429-436. PMID 18042508 DOI: 10.1310/Hct0806-429  0.456
2007 Chang Q, McLinden JH, Stapleton JT, Sathar MA, Xiang J. Expression of GB virus C NS5A protein from genotypes 1, 2, 3 and 5 and a 30 aa NS5A fragment inhibit human immunodeficiency virus type 1 replication in a CD4+ T-lymphocyte cell line. The Journal of General Virology. 88: 3341-6. PMID 18024904 DOI: 10.1099/Vir.0.83198-0  0.552
2007 Handelsman E, Cheng I, Thompson B, Hershow R, Mofenson LM, Hollinger FB, Chen KT, Burchett SK, Klinzman D, Stapleton JT. Impact of GB virus type C infection on mother-to-child HIV transmission in the Women and Infants Transmission Study Cohort. Hiv Medicine. 8: 561-7. PMID 17944690 DOI: 10.1111/J.1468-1293.2007.00510.X  0.512
2007 Scherer CA, Magness CL, Steiger KV, Poitinger ND, Caputo CM, Miner DG, Winokur PL, Klinzman D, McKee J, Pilar C, Ward PA, Gillham MH, Haulman NJ, Stapleton JT, Iadonato SP. Distinct gene expression profiles in peripheral blood mononuclear cells from patients infected with vaccinia virus, yellow fever 17D virus, or upper respiratory infections. Vaccine. 25: 6458-73. PMID 17651872 DOI: 10.1016/J.Vaccine.2007.06.035  0.371
2007 Dillon DM, Stapleton JT. Selenium effects on HIV RNA and CD4 cell counts. Archives of Internal Medicine. 167: 1556-7; author reply. PMID 17646616 DOI: 10.1001/archinte.167.14.1556  0.307
2007 Kaufman TM, McLinden JH, Xiang J, Engel AM, Stapleton JT. The GBV-C envelope glycoprotein E2 does not interact specifically with CD81. Aids (London, England). 21: 1045-8. PMID 17457101 DOI: 10.1097/Qad.0B013E3280F77412  0.425
2007 Chamie G, Bonacini M, Bangsberg DR, Stapleton JT, Hall C, Overton ET, Scherzer R, Tien PC. Factors associated with seronegative chronic hepatitis C virus infection in HIV infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 44: 577-83. PMID 17243063 DOI: 10.1086/511038  0.486
2006 McLinden JH, Kaufman TM, Xiang J, Chang Q, Klinzman D, Engel AM, Hess G, Schmidt U, Houghton M, Stapleton JT. Characterization of an immunodominant antigenic site on GB virus C glycoprotein E2 that is involved in cell binding. Journal of Virology. 80: 12131-40. PMID 17035329 DOI: 10.1128/Jvi.01206-06  0.355
2006 Xiang J, McLinden JH, Chang Q, Kaufman TM, Stapleton JT. An 85-aa segment of the GB virus type C NS5A phosphoprotein inhibits HIV-1 replication in CD4+ Jurkat T cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 15570-5. PMID 17030806 DOI: 10.1073/Pnas.0604728103  0.578
2006 Wunschmann S, Muller HM, Stipp CS, Hemler ME, Stapleton JT. In vitro interaction between hepatitis C virus (HCV) envelope glycoprotein E2 and serum lipoproteins (LPs) results in enhanced cellular binding of both HCV E2 and LPs. The Journal of Infectious Diseases. 194: 1058-67. PMID 16991080 DOI: 10.1086/507647  0.372
2006 Souza IE, Allen JB, Xiang J, Klinzman D, Diaz R, Zhang S, Chaloner K, Zdunek D, Hess G, Williams CF, Benning L, Stapleton JT. Effect of primer selection on estimates of GB virus C (GBV-C) prevalence and response to antiretroviral therapy for optimal testing for GBV-C viremia Journal of Clinical Microbiology. 44: 3105-3113. PMID 16954234 DOI: 10.1128/Jcm.02663-05  0.488
2006 Stapleton JT, Xiang J, Williams CF. HIV and GB virus C coinfection. The Lancet. Infectious Diseases. 6: 187-8; author reply . PMID 16554239 DOI: 10.1016/S1473-3099(06)70419-4  0.547
2006 Zhang W, Chaloner K, Tillmann HL, Williams CF, Stapleton JT. Effect of early and late GB virus C viraemia on survival of HIV-infected individuals: A meta-analysis Hiv Medicine. 7: 173-180. PMID 16494631 DOI: 10.1111/J.1468-1293.2006.00366.X  0.532
2006 George SL, Varmaz D, Stapleton JT. GB virus C replicates in primary T and B lymphocytes. The Journal of Infectious Diseases. 193: 451-4. PMID 16388494 DOI: 10.1086/499435  0.481
2006 Souza IE, Zhang W, Diaz RS, Chaloner K, Klinzman D, Stapleton JT. Effect of GB virus C on response to antiretroviral therapy in HIV-infected Brazilians Hiv Medicine. 7: 25-31. PMID 16313289 DOI: 10.1111/J.1468-1293.2005.00339.X  0.543
2005 Xiang J, Sathar MA, McLinden JH, Klinzman D, Chang Q, Stapleton JT. South African GB virus C isolates: interactions between genotypes 1 and 5 isolates and HIV. The Journal of Infectious Diseases. 192: 2147-51. PMID 16288381 DOI: 10.1086/498170  0.538
2005 Bisson GP, Strom BL, Gross R, Weissman D, Klinzman D, Hwang WT, Kostman JR, Metzger D, Stapleton JT, Frank I. Effect of GB virus C viremia on HIV acquisition and HIV set-point. Aids (London, England). 19: 1910-2. PMID 16227800 DOI: 10.1097/01.Aids.0000188427.25657.E7  0.53
2005 Stapleton JT, Chaloner K, Williams CF. GB virus C infection and survival in the Amsterdam Cohort Study. The Journal of Infectious Diseases. 191: 2157-8; author reply. PMID 15898008 DOI: 10.1086/430505  0.446
2005 Schuval S, Lindsey JC, Stapleton JT, Van Dyke RB, Palumbo P, Mofenson LM, Oleske JM, Cervia J, Kovacs A, Dankner WN, Smith E, Nowak B, Ciupak G, Webb N, Eagle M, et al. GB virus C infection in children with perinatal human immunodeficiency virus infection. The Pediatric Infectious Disease Journal. 24: 417-22. PMID 15876940 DOI: 10.1097/01.Inf.0000160943.17750.94  0.55
2005 Xiang J, Martinez-Smith C, Gale M, Chang Q, Labrecque DR, Schmidt WN, Stapleton JT. GB virus type C NS5A sequence polymorphisms: association with interferon susceptibility and inhibition of PKR-mediated eIF2alpha phosphorylation. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 25: 261-70. PMID 15871663 DOI: 10.1089/Jir.2005.25.261  0.427
2004 Stapleton JT, Chaloner K. GB virus C and survival in HIV-positive people. Aids (London, England). 18: 2343-4; author reply. PMID 15577553 DOI: 10.1097/00002030-200411190-00021  0.512
2004 Stapleton JT, Williams CF, Xiang J. GB virus type C: a beneficial infection? Journal of Clinical Microbiology. 42: 3915-9. PMID 15364968 DOI: 10.1128/Jcm.42.9.3915-3919.2004  0.548
2004 Stapleton JT, Schmidt WN, Katz L. Seronegative hepatitis C virus infection, not just RNA detection. The Journal of Infectious Diseases. 190: 651-2. PMID 15243946 DOI: 10.1086/421282  0.432
2004 Xiang J, George SL, Wünschmann S, Chang Q, Klinzman D, Stapleton JT. Inhibition of HIV-1 replication by GB virus C infection through increases in RANTES, MIP-1alpha, MIP-1beta, and SDF-1. Lancet (London, England). 363: 2040-6. PMID 15207954 DOI: 10.1016/S0140-6736(04)16453-2  0.555
2004 Björkman P, Flamholc L, Widell A, Canducci F, Lazzarin A, Clementi M, Stapleton JT, Williams CF, Xiang J. GB virus C and survival in persons with HIV infection [1] (multiple letters) New England Journal of Medicine. 350: 2617-2618. PMID 15201420 DOI: 10.1056/NEJM200406173502516  0.449
2004 Polgreen PM, Fultz SL, Justice AC, Wagner JH, Diekema DJ, Rabeneck L, Weissman S, Stapleton JT. Association of hypocholesterolaemia with hepatitis C virus infection in HIV-infected people. Hiv Medicine. 5: 144-50. PMID 15139979 DOI: 10.1111/J.1468-1293.2004.00202.X  0.541
2004 Weintrob AC, Hamilton JD, Hahn C, Klinzman D, Moyo G, Zdunek D, Hess G, Benjamin DK, Stapleton JT. Active or prior GB virus C infection does not protect against vertical transmission of HIV in coinfected women from Tanzania. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 38: e46-8. PMID 14999645 DOI: 10.1086/382079  0.553
2004 Williams CF, Klinzman D, Yamashita TE, Xiang J, Polgreen PM, Rinaldo C, Liu C, Phair J, Margolick JB, Zdunek D, Hess G, Stapleton JT. Persistent GB virus C infection and survival in HIV-infected men. The New England Journal of Medicine. 350: 981-90. PMID 14999110 DOI: 10.1056/Nejmoa030107  0.544
2004 Kim SJ, Jang MH, Stapleton JT, Yoon SO, Kim KS, Jeon ES, Hong HJ. Neutralizing human monoclonal antibodies to hepatitis A virus recovered by phage display. Virology. 318: 598-607. PMID 14972527 DOI: 10.1016/J.Virol.2003.10.014  0.308
2004 Ullrich PM, Lutgendorf SK, Stapleton JT, Horowitz M. Self regard and concealment of homosexuality as predictors of CD4+ cell count over time among HIV seropositive gay men Psychology and Health. 19: 183-196. DOI: 10.1080/08870440310001652704  0.385
2003 George SL, Xiang J, Stapleton JT. Clinical isolates of GB virus type C vary in their ability to persist and replicate in peripheral blood mononuclear cell cultures. Virology. 316: 191-201. PMID 14644602 DOI: 10.1016/S0042-6822(03)00585-3  0.457
2003 Polgreen PM, Xiang J, Chang Q, Stapleton JT. GB virus type C/hepatitis G virus: a non-pathogenic flavivirus associated with prolonged survival in HIV-infected individuals. Microbes and Infection / Institut Pasteur. 5: 1255-61. PMID 14623022 DOI: 10.1016/J.Micinf.2003.08.006  0.587
2003 Stapleton JT. GB virus type C/Hepatitis G virus. Seminars in Liver Disease. 23: 137-48. PMID 12800067 DOI: 10.1055/S-2003-39943  0.568
2003 Ullrich PM, Lutgendorf SK, Stapleton JT. Concealment of homosexual identity, social support and CD4 cell count among HIV-seropositive gay men. Journal of Psychosomatic Research. 54: 205-12. PMID 12614830 DOI: 10.1016/S0022-3999(02)00481-6  0.34
2002 George SL, Wünschmann S, McCoy J, Xiang J, Stapleton JT. Interactions Between GB Virus Type C and HIV. Current Infectious Disease Reports. 4: 550-558. PMID 12433333 DOI: 10.1007/S11908-002-0044-9  0.575
2002 George SL, Gebhardt J, Klinzman D, Foster MB, Patrick KD, Schmidt WN, Alden B, Pfaller MA, Stapleton JT. Hepatitis C virus viremia in HIV-infected individuals with negative HCV antibody tests. Journal of Acquired Immune Deficiency Syndromes (1999). 31: 154-62. PMID 12394793 DOI: 10.1097/00126334-200210010-00005  0.426
2002 Xiang J, Wünschmann S, George SL, Klinzman D, Schmidt WN, LaBrecque DR, Stapleton JT. Recombinant hepatitis C virus-like particles expressed by baculovirus: utility in cell-binding and antibody detection assays. Journal of Medical Virology. 68: 537-43. PMID 12376962 DOI: 10.1002/Jmv.10237  0.348
2002 Kresina TF, Flexner CW, Sinclair J, Correia MA, Stapleton JT, Adeniyi-Jones S, Cargill V, Cheever LW. Alcohol use and HIV pharmacotherapy. Aids Research and Human Retroviruses. 18: 757-70. PMID 12167267 DOI: 10.1089/08892220260139495  0.368
2002 Mosier DE, Chisari FV, Macalalad AR, Snydman DR, Takamatsu J, Toyoda H, Fukuda Y, Stapleton JT, Diekema DJ, Xiang J, Tillmann HL, Schmidt RE, Manns MP. GB virus C and mortality from HIV infection [2] (multiple letters) New England Journal of Medicine. 346: 377-379. PMID 11824420 DOI: 10.1056/NEJM200201313460518  0.444
2002 Ullrich PM, Lutgendorf SK, Stapleton JT. Social constraints and depression in HIV infection: Effects of sexual orientation and area of residence Journal of Social and Clinical Psychology. 21: 46-65. DOI: 10.1521/Jscp.21.1.46.22402  0.351
2002 Stapleton JT, Bengel FM, Samo Y, Hallam N, Aguzzi A, DeVeber G. B Virus and HIV infection Biomedicine and Pharmacotherapy. 56: 111. DOI: 10.1016/S0753-3322(02)00167-1  0.405
2001 Schmid W, Stapleton JT, Knight GB, Agnello V. Whole-blood hepatitis C virus RNA extraction methods [4] (multiple letters) Journal of Clinical Microbiology. 39: 3812-3813. PMID 11599521 DOI: 10.1128/Jcm.39.10.3812-3813.2001  0.34
2001 Xiang J, Wunschmann S, Diekema DJ, Klinzman D, Patrick KD, George SL, Stapleton JT. Effect of coinfection with GB virus C on survival among patients with HIV infection New England Journal of Medicine. 345: 707-714. PMID 11547739 DOI: 10.1056/Nejmoa003364  0.582
2000 Wünschmann S, Medh JD, Klinzmann D, Schmidt WN, Stapleton JT. Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor. Journal of Virology. 74: 10055-62. PMID 11024134 DOI: 10.1128/Jvi.74.21.10055-10062.2000  0.364
2000 Vargas K, Messer SA, Pfaller M, Lockhart SR, Stapleton JT, Hellstein J, Soll DR. Elevated phenotypic switching and drug resistance of Candida albicans from human immunodeficiency virus-positive individuals prior to first thrush episode Journal of Clinical Microbiology. 38: 3595-3607. PMID 11015370 DOI: 10.1128/Jcm.38.10.3595-3607.2000  0.369
2000 Xiang J, Wunschmann S, Schmidt W, Shao J, Stapleton JT. Full-length GB virus C (hepatitis G virus) RNA transcripts are infectious in primary CD4-positive T cells Journal of Virology. 74: 9125-9133. PMID 10982359 DOI: 10.1128/Jvi.74.19.9125-9133.2000  0.473
2000 Wunschmann S, Stapleton JT. Fluorescence-based quantitative methods for detecting human immunodeficiency virus type 1-induced syncytia Journal of Clinical Microbiology. 38: 3055-3060. PMID 10921977 DOI: 10.1128/Jcm.38.8.3055-3060.2000  0.47
1999 Xiang J, Daniels KJ, Soll DR, Schmidt WN, LaBrecque DR, Stapleton JT. Visualization and characterization of GB virus-C particles: Evidence for a nucleocapsid Journal of Viral Hepatitis. 6: 16-22. PMID 10760030 DOI: 10.1046/J.1365-2893.1999.00003.X  0.447
1999 George SL, Swindells S, Knudson R, Stapleton JT. Unexplained thrombosis in HIV-infected patients receiving protease inhibitors: Report of seven cases American Journal of Medicine. 107: 624-626. PMID 10625032 DOI: 10.1016/S0002-9343(99)00296-X  0.42
1999 Cederna JB, Klinzman D, Stapleton JT. Hepatitis A virus-specific humoral and cellular immune responses following immunization with a formalin-inactivated hepatitis A vaccine Vaccine. 18: 892-898. PMID 10580203 DOI: 10.1016/S0264-410X(99)00342-4  0.326
1999 Herman RA, Noormohamed S, Hirankarn S, Shelton MJ, Huang E, Morse GD, Hewitt RG, Stapleton JT. Comparison of a neural network approach with five traditional methods for predicting creatinine clearance in patients with human immunodeficiency virus infection. Pharmacotherapy. 19: 734-40. PMID 10391419 DOI: 10.1592/Phco.19.9.734.31545  0.397
1999 Ullrich P, Lutgendorf S, Stapleton J. HIV IN METROPOLITAN AND NON-METROPOLITAN AREAS Psychosomatic Medicine. 61: 119. DOI: 10.1097/00006842-199901000-00191  0.303
1998 Noormohamed SE, Katseres JK, Stapleton JT. Poor correlation between published methods to predict creatinine clearance and measured creatinine clearance in asymptomatic HIV infected individuals Renal Failure. 20: 627-633. PMID 9713882 DOI: 10.3109/08860229809045156  0.436
1998 Xiang J, Klinzman D, McLinden J, Schmidt WN, LaBrecque DR, Gish R, Stapleton JT. Characterization of hepatitis G virus (GB-C virus) particles: Evidence for a nucleocapsid and expression of sequences upstream of the E1 protein Journal of Virology. 72: 2738-2744. PMID 9525592  0.306
1997 Schmidt WN, Wu P, Cederna J, Mitros FA, LaBrecque DR, Stapleton JT. Surreptitious hepatitis C virus (HCV) infection detected in the majority of patients with cryptogenic chronic hepatitis and negative HCV antibody tests Journal of Infectious Diseases. 176: 27-33. PMID 9207346 DOI: 10.1086/514033  0.353
1997 Schmidt WN, Wu P, Han JQ, Perino MJ, LaBrecque DR, Stapleton JT. Distribution of hepatitis C virus (HCV) RNA in whole blood and blood cell fractions: Plasma HCV RNA analysis underestimates circulating virus load Journal of Infectious Diseases. 176: 20-26. PMID 9207345 DOI: 10.1086/514024  0.333
1995 Stapleton JT. Host immune response to hepatitis a virus Journal of Infectious Diseases. 171. PMID 7876654 DOI: 10.1093/Infdis/171.Supplement_1.S9  0.328
1995 Sylwester A, Shutt D, Wessels D, Stapleton JT, Stites J, Kennedy RC, Soll DR. T cells and HIV-induced T cell syncytia exhibit the same motility cycle. Journal of Leukocyte Biology. 57: 643-50. PMID 7722421 DOI: 10.1002/Jlb.57.4.643  0.411
1995 Shutt DC, Stapleton JT, Kennedy RC, Soll DR. HIV-induced syncytia in peripheral blood cell cultures crawl by extending giant pseudopods. Cellular Immunology. 166: 261-74. PMID 7497528 DOI: 10.1006/Cimm.1995.9971  0.44
1993 Naides SJ, Howard EJ, Swack NS, True CA, Stapleton JT. Parvovirus B19 infection in human immunodeficiency virus type 1-infected persons failing or intolerant to zidovudine therapy. The Journal of Infectious Diseases. 168: 101-5. PMID 8515096 DOI: 10.1093/Infdis/168.1.101  0.31
1993 Rosen E, Stapleton JT, McLinden J. Synthesis of immunogenic hepatitis A virus particles by recombinant baculoviruses Vaccine. 11: 706-712. PMID 8393604 DOI: 10.1016/0264-410X(93)90253-T  0.377
1992 Stapleton JT. Passive immunization against hepatitis A Vaccine. 10. PMID 1335658 DOI: 10.1016/0264-410X(92)90541-Q  0.349
1992 Davis KA, Cameron B, Stapleton JT. The impact of HIV patient migration to rural areas Aids Patient Care. 6: 225-228. DOI: 10.1089/Apc.1992.6.225  0.392
1991 Stapleton JT, Lange DK, LeDuc JW, Binn LN, Jansen RW, Lemon SM. The role of secretory immunity in hepatitis A virus infection Journal of Infectious Diseases. 163: 7-11. PMID 1845810 DOI: 10.1093/Infdis/163.1.7  0.385
1991 Stapleton JT, Frederick J, Meyer B. Hepatitis A virus attachment to cultured cell lines Journal of Infectious Diseases. 164: 1098-1103. PMID 1659597 DOI: 10.1093/Infdis/164.6.1098  0.343
1991 Davis K, Stapleton J. Migration to Rural Areas by HIV Patients Impact on HIV-Related Healthcare Use Infection Control and Hospital Epidemiology. 12: 540-543. DOI: 10.2307/30145229  0.425
1990 Lemon SM, Binn LN, Marchwicki R, Murphy PC, Ping LH, Jansen RW, Asher LVS, Stapleton JT, Taylor DG, LeDuc JW. In vivo replication and reversion to wild type of a neutralization-resistant antigenic variant of hepatitis A virus Journal of Infectious Diseases. 161: 7-13. PMID 1688601 DOI: 10.1093/Infdis/161.1.7  0.352
1988 Shamsuddin H, Stapleton JT. HIV infection: manifestations, therapy and transmission Iowa Medicine : Journal of the Iowa Medical Society. 78: 125-128. PMID 3350630  0.342
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