Charles A. Downs, Ph.D. - Publications

Affiliations: 
2011 Nursing University of Arizona, Tucson, AZ 
Area:
Toxicology, Cell Biology, Nursing

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Downs CA, Johnson NM, Tsaprailis G, Helms MN. RAGE-induced changes in the proteome of alveolar epithelial cells. Journal of Proteomics. 177: 11-20. PMID 29448054 DOI: 10.1016/J.Jprot.2018.02.010  0.336
2017 Downs CA, Johnson NM, Coca C, Helms MN. Angiotensin II regulates δ-ENaC in human umbilical vein endothelial cells. Microvascular Research. PMID 29051045 DOI: 10.1016/J.Mvr.2017.10.001  0.327
2017 Downs CA, Dang VD, Johnson NM, Denslow N, Alli AA. Hydrogen peroxide stimulates exosomal cathepsin B regulation of the receptor for advanced glycation end-products (RAGE). Journal of Cellular Biochemistry. PMID 28618037 DOI: 10.1002/Jcb.26219  0.366
2015 Downs CA, Kreiner L, Zhao XM, Trac P, Johnson NM, Hansen JM, Brown LA, Helms MN. Oxidized glutathione (GSSG) inhibits epithelial sodium channel activity in primary alveolar epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L943-52. PMID 25713321 DOI: 10.1152/Ajplung.00213.2014  0.345
2015 Downs CA, Kreiner LH, Johnson NM, Brown LA, Helms MN. Receptor for advanced glycation end-products regulates lung fluid balance via protein kinase C-gp91(phox) signaling to epithelial sodium channels. American Journal of Respiratory Cell and Molecular Biology. 52: 75-87. PMID 24978055 DOI: 10.1165/Rcmb.2014-0002Oc  0.329
2013 Trac D, Liu B, Pao AC, Thomas SV, Park M, Downs CA, Ma HP, Helms MN. Fulvene-5 inhibition of Nadph oxidases attenuates activation of epithelial sodium channels in A6 distal nephron cells. American Journal of Physiology. Renal Physiology. 305: F995-F1005. PMID 23863470 DOI: 10.1152/Ajprenal.00098.2013  0.336
2013 Downs CA, Kreiner LH, Trac DQ, Helms MN. Acute effects of cigarette smoke extract on alveolar epithelial sodium channel activity and lung fluid clearance. American Journal of Respiratory Cell and Molecular Biology. 49: 251-9. PMID 23526224 DOI: 10.1165/Rcmb.2012-0234Oc  0.405
2013 Downs CA, Trac DQ, Kreiner LH, Eaton AF, Johnson NM, Brown LA, Helms MN. Ethanol alters alveolar fluid balance via Nadph oxidase (NOX) signaling to epithelial sodium channels (ENaC) in the lung. Plos One. 8: e54750. PMID 23382956 DOI: 10.1371/Journal.Pone.0054750  0.309
2013 Downs CA, Kumar A, Kreiner LH, Johnson NM, Helms MN. H2O2 regulates lung epithelial sodium channel (ENaC) via ubiquitin-like protein Nedd8. The Journal of Biological Chemistry. 288: 8136-45. PMID 23362276 DOI: 10.1074/Jbc.M112.389536  0.337
2012 Downs CA, Kriener LH, Yu L, Eaton DC, Jain L, Helms MN. β-Adrenergic agonists differentially regulate highly selective and nonselective epithelial sodium channels to promote alveolar fluid clearance in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L1167-78. PMID 22505670 DOI: 10.1152/Ajplung.00038.2012  0.319
2011 Downs CA, Montgomery DW, Merkle CJ. Age-related differences in cigarette smoke extract-induced H2O2 production by lung endothelial cells. Microvascular Research. 82: 311-7. PMID 22001394 DOI: 10.1016/J.Mvr.2011.09.013  0.644
2011 Downs CA, Montgomery DW, Merkle CJ. Cell culture models using rat primary alveolar type I cells. Pulmonary Pharmacology & Therapeutics. 24: 577-86. PMID 21624488 DOI: 10.1016/J.Pupt.2011.05.005  0.634
2011 Downs CA, Montgomery DW, Merkle CJ. Alveolar Epithelial Type I Cells Attenuate Cigarette Smoke Extract-Induced Production of Hydrogen Peroxide by Microvascular Endothelial Cells Free Radical Biology and Medicine. 51: S110-S111. DOI: 10.1016/J.Freeradbiomed.2011.10.347  0.633
2010 Downs CA, Fauth JE, Downs VD, Ostrander GK. In vitro cell-toxicity screening as an alternative animal model for coral toxicology: effects of heat stress, sulfide, rotenone, cyanide, and cuprous oxide on cell viability and mitochondrial function. Ecotoxicology (London, England). 19: 171-84. PMID 19757033 DOI: 10.1007/S10646-009-0403-5  0.313
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