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Steven E. Arnold, MD - Publications

Affiliations: 
Center for Neurobiology and Behavior University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cellular and molecular neurobiology of schizophrenia and mood disorders, aging and neurodegenerative dementias
Website:
http://www.med.upenn.edu/ins/faculty/arnold.htm

239 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yang HS, Yau WW, Carlyle BC, Trombetta BA, Zhang C, Shirzadi Z, Schultz AP, Pruzin JJ, Fitzpatrick CD, Kirn DR, Rabin JS, Buckley RF, Hohman TJ, Rentz DM, Tanzi RE, ... ... Arnold SE, et al. Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease. Brain : a Journal of Neurology. PMID 38315899 DOI: 10.1093/brain/awae034  0.34
2024 Lacar B, Ferdosi S, Alavi A, Stukalov A, Venkataraman GR, de Geus M, Dodge H, Wu CY, Kivisakk P, Das S, Guturu H, Hyman B, Batzoglou S, Arnold SE, Siddiqui A. Identification of Novel Biomarkers for Alzheimer's Disease and Related Dementias Using Unbiased Plasma Proteomics. Biorxiv : the Preprint Server For Biology. PMID 38260620 DOI: 10.1101/2024.01.05.574446  0.317
2023 Kivisäkk P, Carlyle BC, Sweeney T, Trombetta BA, LaCasse K, El-Mufti L, Tuncali I, Chibnik LB, Das S, Scherzer CR, Johnson KA, Dickerson BC, Gomez-Isla T, Blacker D, Oakley DH, ... ... Arnold SE, et al. Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment. Frontiers in Neurology. 14: 1069411. PMID 36937522 DOI: 10.3389/fneur.2023.1069411  0.341
2023 Quinn JP, Ethier EC, Novielli A, Malone A, Ramirez CE, Salloum L, Trombetta BA, Kivisäkk P, Bremang M, Selzer S, Fournier M, Das S, Xing Y, Arnold SE, Carlyle BC. Cerebrospinal Fluid and Brain Proteoforms of the Granin Neuropeptide Family in Alzheimer's Disease. Journal of the American Society For Mass Spectrometry. PMID 36912488 DOI: 10.1021/jasms.2c00341  0.324
2023 Azami H, Moguilner S, Penagos H, Sarkis RA, Arnold SE, Gomperts SN, Lam AD. EEG Entropy in REM Sleep as a Physiologic Biomarker in Early Clinical Stages of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 36641682 DOI: 10.3233/JAD-221152  0.644
2022 Ko YA, Billheimer JT, Lyssenko NN, Kueider-Paisley A, Wolk DA, Arnold SE, Leung YY, Shaw LM, Trojanowski JQ, Kaddurah-Daouk RF, Kling MA, Rader DJ. ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease. Alzheimer's Research & Therapy. 14: 194. PMID 36572909 DOI: 10.1186/s13195-022-01119-z  0.49
2022 Azami H, Chang Z, Arnold SE, Sapiro G, Gupta AS. Detection of Oculomotor Dysmetria From Mobile Phone Video of the Horizontal Saccades Task Using Signal Processing and Machine Learning Approaches. Ieee Access : Practical Innovations, Open Solutions. 10: 34022-34031. PMID 36339795 DOI: 10.1109/access.2022.3156964  0.581
2021 Carlyle BC, Kandigian SE, Kreuzer J, Das S, Trombetta BA, Kuo Y, Bennett DA, Schneider JA, Petyuk VA, Kitchen RR, Morris R, Nairn AC, Hyman BT, Haas W, Arnold SE. Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics. Neurobiology of Aging. 105: 99-114. PMID 34052751 DOI: 10.1016/j.neurobiolaging.2021.04.012  0.326
2021 Fong TG, Vasunilashorn SM, Gou Y, Libermann TA, Dillon S, Schmitt E, Arnold SE, Kivisäkk P, Carlyle B, Oh ES, Vlassakov K, Kunze L, Hshieh T, Jones RN, Marcantonio ER, et al. Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults. Alzheimer's & Dementia (New York, N. Y.). 7: e12125. PMID 33748398 DOI: 10.1002/trc2.12125  0.319
2020 DesRuisseaux LA, Williams VJ, McManus AJ, Gupta AS, Carlyle BC, Azami H, Gerber JA, Bolling AM, Cook CL, Betensky RA, Arnold SE. A pilot protocol to assess the feasibility of a virtual multiple crossover, randomized controlled trial design using methylphenidate in mild cognitive impairment. Trials. 21: 1016. PMID 33308285 DOI: 10.1186/s13063-020-04752-x  0.636
2020 Bryant AG, Hu M, Carlyle BC, Arnold SE, Frosch MP, Das S, Hyman BT, Bennett RE. Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. Frontiers in Neurology. 11: 575953. PMID 33041998 DOI: 10.3389/Fneur.2020.575953  0.379
2020 Arvanitakis Z, Wang HY, Capuano AW, Khan A, Taïb B, Anokye-Danso F, Schneider JA, Bennett DA, Ahima RS, Arnold SE. Brain insulin signaling, Alzheimer's disease pathology, and cognitive function. Annals of Neurology. PMID 32557841 DOI: 10.1002/Ana.25826  0.409
2020 Vallabh SM, Minikel EV, Williams VJ, Carlyle BC, McManus AJ, Wennick CD, Bolling A, Trombetta BA, Urick D, Nobuhara CK, Gerber J, Duddy H, Lachmann I, Stehmann C, Collins SJ, ... ... Arnold SE, et al. Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease. Bmc Medicine. 18: 140. PMID 32552681 DOI: 10.1186/S12916-020-01608-8  0.326
2019 Daiello LA, Racine AM, Yun Gou R, Marcantonio ER, Xie Z, Kunze LJ, Vlassakov KV, Inouye SK, Jones RN, Alsop D, Travison T, Arnold S, Cooper Z, Dickerson B, Fong T, et al. Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence. Anesthesiology. PMID 31166241 DOI: 10.1097/Aln.0000000000002729  0.318
2019 Vallabh SM, Nobuhara CK, Llorens F, Zerr I, Parchi P, Capellari S, Kuhn E, Klickstein J, Safar JG, Nery FC, Swoboda KJ, Geschwind MD, Zetterberg H, Arnold SE, Minikel EV, et al. Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development. Proceedings of the National Academy of Sciences of the United States of America. PMID 30936307 DOI: 10.1073/Pnas.1901947116  0.302
2019 Capuano AW, Wilson RS, Honer WG, Petyuk VA, Leurgans SE, Yu L, Gatchel JR, Arnold S, Bennett DA, Arvanitakis Z. Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons. Journal of Affective Disorders. 250: 313-318. PMID 30875674 DOI: 10.1016/J.Jad.2019.03.051  0.327
2019 Azami H, Li P, Arnold SE, Escudero J, Humeau-Heurtier A. Fuzzy Entropy Metrics for the Analysis of Biomedical Signals: Assessment and Comparison Ieee Access. 7: 104833-104847. DOI: 10.1109/Access.2019.2930625  0.612
2019 Azami H, Arnold SE, Sanei S, Chang Z, Sapiro G, Escudero J, Gupta AS. Multiscale Fluctuation-Based Dispersion Entropy and Its Applications to Neurological Diseases Ieee Access. 7: 68718-68733. DOI: 10.1109/Access.2019.2918560  0.72
2019 Leslie S, Wilson R, Kivisäkk P, Kandigian SE, Trombetta BA, Nairn AC, Arnold SE, Carlyle BC. P1-269: Development And Technical Validation Of A Data-Independent Acquisition Methodology For Analysis Of Human Alzheimer'S Disease Cerebrospinal Fluid Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.824  0.35
2019 Carlyle BC, Kandigian SE, Trombetta BA, Haas W, Arnold SE. PROTEOMIC ASSESSMENT OF SYNAPSES WITH RICH ASSOCIATED CLINICAL DATA HIGHLIGHTS POTENTIAL TARGETS FOR MEDIATING ALZHEIMER’S PATHOLOGY AND COGNITIVE DECLINE Alzheimer's & Dementia. 15: P192-P193. DOI: 10.1016/J.Jalz.2019.06.4521  0.34
2019 Trombetta BA, Kandigian SE, Williams VJ, Kivisäkk P, Carlyle BC, Arnold SE. P4-217: A MULTIPLE PATHOPHYSIOLOGY PANEL FOR CLINICAL TRIALS IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P1359-P1359. DOI: 10.1016/J.Jalz.2019.06.3880  0.366
2019 Kandigian SE, Trombetta BA, Kanyo JE, Arnold SE, Carlyle BC. P4-173: SUBCELLULAR ORGANELLE FRACTIONATION FOR PROTEOMIC ANALYSIS IN POSTMORTEM ALZHEIMER'S DISEASE TISSUE Alzheimer's & Dementia. 15: P1341-P1341. DOI: 10.1016/J.Jalz.2019.06.3835  0.356
2019 Azami H, Escudero J, Fernandez A, Arnold SE. P2-405: AMPLITUDE- AND FLUCTUATION-BASED DISPERSION ENTROPY FOR THE ANALYSIS OF RESTING-STATE MAGNETOENCEPHALOGRAM IRREGULARITY IN MCI AND ALZHEIMER'S DISEASE PATIENTS Alzheimer's & Dementia. 15: P762-P762. DOI: 10.1016/J.Jalz.2019.06.2812  0.685
2018 Gangishetti U, Christina Howell J, Perrin RJ, Louneva N, Watts KD, Kollhoff A, Grossman M, Wolk DA, Shaw LM, Morris JC, Trojanowski JQ, Fagan AM, Arnold SE, Hu WT. Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer's disease. Alzheimer's Research & Therapy. 10: 98. PMID 30253800 DOI: 10.1186/S13195-018-0426-3  0.58
2018 Carlyle BC, Trombetta BA, Arnold SE. Proteomic Approaches for the Discovery of Biofluid Biomarkers of Neurodegenerative Dementias. Proteomes. 6. PMID 30200280 DOI: 10.3390/Proteomes6030032  0.373
2018 Arnold SE, Betensky RA. Multi-crossover randomized controlled trial designs in Alzheimer's disease. Annals of Neurology. PMID 30014506 DOI: 10.1002/Ana.25280  0.34
2018 Robinson JL, Lee EB, Xie SX, Rennert L, Suh E, Bredenberg C, Caswell C, Van Deerlin VM, Yan N, Yousef A, Hurtig HI, Siderowf A, Grossman M, McMillan CT, Miller B, ... ... Arnold SE, et al. Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated. Brain : a Journal of Neurology. PMID 29878075 DOI: 10.1093/Brain/Awy146  0.558
2018 Trombetta BA, Carlyle BC, Koenig AM, Shaw LM, Trojanowski JQ, Wolk DA, Locascio JJ, Arnold SE. The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer's disease. Plos One. 13: e0193707. PMID 29505610 DOI: 10.1371/Journal.Pone.0193707  0.57
2018 Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, Terrando N, Newman MF, Doraiswamy PM, Mathew JP, Weiner MW, Aisen P, Weiner M, Aisen P, ... ... Arnold SE, et al. 18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery. Anesthesiology. PMID 29389750 DOI: 10.1097/Aln.0000000000002103  0.448
2018 Arnold SE, Arvanitakis Z, Macauley-Rambach SL, Koenig AM, Wang HY, Ahima RS, Craft S, Gandy S, Buettner C, Stoeckel LE, Holtzman DM, Nathan DM. Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums. Nature Reviews. Neurology. PMID 29377010 DOI: 10.1038/Nrneurol.2017.185  0.321
2017 Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, ... ... Arnold SE, et al. Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia. Jama Psychiatry. PMID 29188296 DOI: 10.1001/Jamapsychiatry.2017.3391  0.573
2017 Lanctôt KL, Amatniek J, Ancoli-Israel S, Arnold SE, Ballard C, Cohen-Mansfield J, Ismail Z, Lyketsos C, Miller DS, Musiek E, Osorio RS, Rosenberg PB, Satlin A, Steffens D, Tariot P, et al. Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms. Alzheimer's & Dementia (New York, N. Y.). 3: 440-449. PMID 29067350 DOI: 10.1016/J.Trci.2017.07.001  0.415
2017 Kimchi EY, Hshieh TT, Guo R, Wong B, O'Connor M, Marcantonio ER, Metzger ED, Strauss J, Arnold SE, Inouye SK, Fong TG. Consensus Approaches to Identify Incident Dementia in Cohort Studies: Systematic Review and Approach in the Successful Aging after Elective Surgery Study. Journal of the American Medical Directors Association. PMID 28927945 DOI: 10.1016/J.Jamda.2017.07.014  0.34
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Arnold SE, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.343
2017 Koenig AM, Mechanic-Hamilton D, Xie SX, Combs MF, Cappola AR, Xie L, Detre JA, Wolk DA, Arnold SE. Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study. Alzheimer Disease and Associated Disorders. 31: 107-113. PMID 28538088 DOI: 10.1097/Wad.0000000000000202  0.58
2017 Roalf DR, Moore TM, Mechanic-Hamilton D, Wolk DA, Arnold SE, Weintraub DA, Moberg PJ. Bridging cognitive screening tests in neurologic disorders: A crosswalk between the short Montreal Cognitive Assessment and Mini-Mental State Examination. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28238740 DOI: 10.1016/J.Jalz.2017.01.015  0.511
2017 Sepulveda V, Arnold SE, Jimenez-Velazquez IZ, Wojna V. ARE INSULIN RESISTANCE AND CEREBROSPINAL FLUID BIOMARKERS CORRELATED IN PUERTO RICANS WITH MINIMAL COGNITIVE IMPAIRMENT AND EARLY ALZHEIMER’S DISEASE? Alzheimer's & Dementia. 13: P1517. DOI: 10.1016/J.Jalz.2017.07.638  0.344
2017 Gangishetti U, Perrin RJ, Arnold SE, Fagan AM, Morris JC, Trojanowski JQ, Hu WT. VALIDATING NON-AMYLOID, NON-TAU CSF BIOMARKERS FOR ALZHEIMER'S DISEASE IN THE PRE-SYMPTOMATIC, MCI, AND DEMENTIA STAGES: A MULTI-CENTER STUDY Alzheimer's & Dementia. 13: P1513-P1514. DOI: 10.1016/J.Jalz.2017.07.632  0.412
2016 Yarchoan M, James BD, Shah RC, Arvanitakis Z, Wilson RS, Schneider J, Bennett DA, Arnold SE. Association of Cancer History with Alzheimer's Disease Dementia and Neuropathology. Journal of Alzheimer's Disease : Jad. PMID 28035936 DOI: 10.3233/Jad-160977  0.409
2016 Quarmley M, Moberg PJ, Mechanic-Hamilton D, Kabadi S, Arnold SE, Wolk DA, Roalf DR. Odor Identification Screening Improves Diagnostic Classification in Incipient Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27886011 DOI: 10.3233/Jad-160842  0.592
2016 Pruzin JJ, Schneider JA, Capuano AW, Leurgans SE, Barnes LL, Ahima RS, Arnold SE, Bennett DA, Arvanitakis Z. Diabetes, Hemoglobin A1C, and Regional Alzheimer Disease and Infarct Pathology. Alzheimer Disease and Associated Disorders. PMID 27755004 DOI: 10.1097/Wad.0000000000000172  0.329
2016 Roalf DR, Quarmley M, Mechanic-Hamilton D, Wolk DA, Arnold SE, Moberg PJ. Within-Individual Variability: An Index for Subtle Change in Neurocognition in Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. 54: 325-35. PMID 27567827 DOI: 10.3233/Jad-160259  0.546
2016 Roalf DR, Moore TM, Wolk DA, Arnold SE, Mechanic-Hamilton D, Rick J, Kabadi S, Ruparel K, Chen-Plotkin AS, Chahine LM, Dahodwala NA, Duda JE, Weintraub DA, Moberg PJ. Defining and validating a short form Montreal Cognitive Assessment (s-MoCA) for use in neurodegenerative disease. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27071646 DOI: 10.1136/Jnnp-2015-312723  0.547
2016 Camacho-Mercado CL, Figueroa R, Acosta H, Arnold SE, Vega IE. Profiling of Alzheimer's disease patients in Puerto Rico: A comparison of two distinct socioeconomic areas. Sage Open Medicine. 4: 2050312115627826. PMID 26893902 DOI: 10.1177/2050312115627826  0.334
2016 Chen Y, Bang S, McMullen MF, Kazi H, Talbot K, Ho MX, Carlson G, Arnold SE, Ong WY, Kim SF. Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice-Potential Link to Cognitive Impairment in Schizophrenia. Molecular Neurobiology. PMID 26873854 DOI: 10.1007/S12035-016-9773-X  0.305
2016 Koenig AM, Arnold SE, Streim JE. Agitation and Irritability in Alzheimer's Disease: Evidenced-Based Treatments and the Black-Box Warning. Current Psychiatry Reports. 18: 3. PMID 26695173 DOI: 10.1007/S11920-015-0640-7  0.371
2016 Ahima RS, Capuano AW, Schneider JA, Bennett DA, Arnold SE, Arvanitakis Z. P2-107: Brain Insulin Resistance and Alzheimer's Disease Neuropathology Among Older Autopsied Persons With and Without Diabetes Alzheimer's & Dementia. 12: P653-P653. DOI: 10.1016/J.Jalz.2016.06.1313  0.322
2015 Cecchi M, Moore DK, Sadowsky CH, Solomon PR, Doraiswamy PM, Smith CD, Jicha GA, Budson AE, Arnold SE, Fadem KC. A clinical trial to validate event-related potential markers of Alzheimer's disease in outpatient settings. Alzheimer's & Dementia (Amsterdam, Netherlands). 1: 387-94. PMID 27239520 DOI: 10.1016/J.Dadm.2015.08.004  0.423
2015 Toledo JB, Gopal P, Raible K, Irwin DJ, Brettschneider J, Sedor S, Waits K, Boluda S, Grossman M, Van Deerlin VM, Lee EB, Arnold SE, Duda JE, Hurtig H, Lee VM, et al. Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology. Acta Neuropathologica. PMID 26721587 DOI: 10.1007/S00401-015-1526-9  0.368
2015 Leung YY, Toledo JB, Nefedov A, Polikar R, Raghavan N, Xie SX, Farnum M, Schultz T, Baek Y, Deerlin VV, Hu WT, Holtzman DM, Fagan AM, Perrin RJ, Grossman M, ... ... Arnold SE, et al. Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study. Alzheimer's & Dementia (Amsterdam, Netherlands). 1: 339-348. PMID 26693175 DOI: 10.1016/J.Dadm.2015.06.008  0.447
2015 Irwin DJ, Brettschneider J, McMillan CT, Cooper F, Olm C, Arnold SE, Van Deerlin VM, Seeley WW, Miller BL, Lee EB, Lee VM, Grossman M, Trojanowski JQ. Deep Clinical and Neuropathological Phenotyping of Pick's Disease. Annals of Neurology. PMID 26583316 DOI: 10.1002/Ana.24559  0.34
2015 Irwin DJ, Byrne MD, McMillan CT, Cooper F, Arnold SE, Lee EB, Van Deerlin VM, Xie SX, Lee VM, Grossman M, Trojanowski JQ. Semi-Automated Digital Image Analysis of Pick's Disease and TDP-3 Proteinopathy. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. PMID 26538548 DOI: 10.1369/0022155415614303  0.334
2015 Toledo JB, Bjerke M, Chen K, Rozycki M, Jack CR, Weiner MW, Arnold SE, Reiman EM, Davatzikos C, Shaw LM, Trojanowski JQ. Memory, executive, and multidomain subtle cognitive impairment: Clinical and biomarker findings. Neurology. 85: 144-53. PMID 26085606 DOI: 10.1016/J.Jalz.2015.06.1758  0.31
2015 Negash S, Kliot D, Howard DV, Howard JH, Das SR, Yushkevich PA, Pluta JB, Arnold SE, Wolk DA. Relationship of contextual cueing and hippocampal volume in amnestic mild cognitive impairment patients and cognitively normal older adults. Journal of the International Neuropsychological Society : Jins. 21: 285-96. PMID 25991413 DOI: 10.1017/S1355617715000223  0.499
2015 Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FR, Visser PJ, Aalten P, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, et al. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. Jama. 313: 1924-38. PMID 25988462 DOI: 10.1001/Jama.2015.4668  0.506
2015 Kandel BM, Avants BB, Gee JC, Arnold SE, Wolk DA. Neuropsychological Testing Predicts Cerebrospinal Fluid Amyloid-β in Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 25881908 DOI: 10.3233/Jad-142943  0.58
2015 Das SR, Mancuso L, Olson IR, Arnold SE, Wolk DA. Short-Term Memory Depends on Dissociable Medial Temporal Lobe Regions in Amnestic Mild Cognitive Impairment. Cerebral Cortex (New York, N.Y. : 1991). PMID 25725042 DOI: 10.1093/Cercor/Bhv022  0.538
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Arnold SE, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.404
2015 Cecchi M, Moore D, Sadowsky CH, Solomon P, Doraiswamy M, Smith CD, Jicha GA, Budson A, Arnold SE. P2-080: Neuropsychological correlates of erp cognitive measures in Alzheimer's disease Alzheimer's & Dementia. 11: P514-P514. DOI: 10.1016/J.Jalz.2015.06.617  0.417
2015 Kansal K, Kamath V, Mechanic-Hamilton D, Irwin DJ, Moberg PJ, Turetsky BI, Grossman M, Arnold SE, Onyike CU. Odor identification in frontotemporal dementia, Alzheimer’s disease, and major depression Alzheimers & Dementia. 11: 375. DOI: 10.1016/J.Jalz.2015.06.292  0.319
2015 Partch AB, Laufer D, Valladares O, Iodice J, Greenfest-Allen E, Childress DM, Malamon J, Gangadharan P, Arnold SE, Stoeckert CJ, Schellenberg GD, Wang L. P1-061: Nia genetics of Alzheimer's disease data storage site (NIAGADS): 2015 update Alzheimer's & Dementia. 11: P362-P362. DOI: 10.1016/J.Jalz.2015.06.258  0.336
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/S00401-014-1349-0  0.458
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Arnold SE, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.334
2014 Glenn M, Mace L, Shaw L, Arnold S, Wolk D, Moelter S. A-79Primacy-Weighted Retrieval Differences in Healthy Older Adults with Pathological or Normal Cerebrospinal Fluid Markers of Alzheimer's Disease. Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists. 29: 532. PMID 25176741 DOI: 10.1093/Arclin/Acu038.79  0.525
2014 Yarchoan M, Toledo JB, Lee EB, Arvanitakis Z, Kazi H, Han LY, Louneva N, Lee VM, Kim SF, Trojanowski JQ, Arnold SE. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathologica. 128: 679-89. PMID 25107476 DOI: 10.1007/S00401-014-1328-5  0.374
2014 Wilson RS, Capuano AW, Boyle PA, Hoganson GM, Hizel LP, Shah RC, Nag S, Schneider JA, Arnold SE, Bennett DA. Clinical-pathologic study of depressive symptoms and cognitive decline in old age. Neurology. 83: 702-9. PMID 25080520 DOI: 10.1212/Wnl.0000000000000715  0.31
2014 Yarchoan M, Arnold SE. Repurposing diabetes drugs for brain insulin resistance in Alzheimer disease. Diabetes. 63: 2253-61. PMID 24931035 DOI: 10.2337/Db14-0287  0.385
2014 Toledo JB, Weiner MW, Wolk DA, Da X, Chen K, Arnold SE, Jagust W, Jack C, Reiman EM, Davatzikos C, Shaw LM, Trojanowski JQ. Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition. Acta Neuropathologica Communications. 2: 26. PMID 24602322 DOI: 10.1186/2051-5960-2-26  0.574
2014 Toledo JB, Da X, Weiner MW, Wolk DA, Xie SX, Arnold SE, Davatzikos C, Shaw LM, Trojanowski JQ. CSF Apo-E levels associate with cognitive decline and MRI changes. Acta Neuropathologica. 127: 621-32. PMID 24385135 DOI: 10.1007/S00401-013-1236-0  0.546
2014 Bennett DA, Arnold SE, Valenzuela MJ, Brayne C, Schneider JA. Cognitive and social lifestyle: links with neuropathology and cognition in late life. Acta Neuropathologica. 127: 137-50. PMID 24356982 DOI: 10.1007/S00401-013-1226-2  0.365
2014 Adler BL, Yarchoan M, Hwang HM, Louneva N, Blair JA, Palm R, Smith MA, Lee HG, Arnold SE, Casadesus G. Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition. Neurobiology of Aging. 35: 793-801. PMID 24239383 DOI: 10.1016/J.Neurobiolaging.2013.10.076  0.42
2014 Toledo JB, Van Deerlin VM, Lee EB, Suh E, Baek Y, Robinson JL, Xie SX, McBride J, Wood EM, Schuck T, Irwin DJ, Gross RG, Hurtig H, McCluskey L, Elman L, ... ... Arnold SE, et al. A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 477-84.e1. PMID 23978324 DOI: 10.1016/J.Jalz.2013.06.003  0.512
2014 Mathews SB, Arnold SE, Epperson CN. Hospitalization and cognitive decline: Can the nature of the relationship be deciphered? The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 22: 465-80. PMID 23567430 DOI: 10.1016/J.Jagp.2012.08.012  0.321
2014 Leinonen V, Rinne J, Wong D, Wolk DA, Arnold SE, Trojanowski JQ, Sherwin P, Smith A, Heurling K, Henry E, Grachev ID. P3-189: DIAGNOSTIC EFFECTIVENESS OF QUANTITATIVE [18F]FLUTEMETAMOL PET IMAGING IN SUBJECTS WITH NORMAL PRESSURE HYDROCEPHALUS USING BIOPSY HISTOPATHOLOGY STANDARD OF TRUTH FOR DETECTION OF FIBRILLAR AMYLOID B Alzheimer's & Dementia. 10: P699-P699. DOI: 10.1016/J.Jalz.2014.05.1279  0.462
2014 Wang L, Wang L, Valladares O, Childress DM, Partch A, Laufer D, Iodice J, Lawrence C, Hu T, Malamon J, Tang M, Lin C, Arnold SE, Stoeckert CJ, Schellenberg GD. P3-020: NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE (NIAGADS): 2014 UPDATE Alzheimer's & Dementia. 10: P634-P635. DOI: 10.1016/J.Jalz.2014.05.1107  0.302
2014 Cecchi M, Sadowsky C, Solomon P, Doraiswamy PM, Smith C, Jicha GA, Budson A, Arnold SE. O3-13-05: EVALUATION OF EVENT RELATED POTENTIALS AND QUANTITATIVE EEG AS USEFUL BIOMARKERS FOR THE DIAGNOSIS OF EARLY-STAGE ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P236-P236. DOI: 10.1016/J.Jalz.2014.04.345  0.383
2014 Schoen M, Richardson K, French B, Mitchell MD, Arnold SE, Heidenreich PA, Rader DJ, Umscheid CA, deGoma EM. Statins and Cognitive Function: A Systematic Review†∗ Journal of Clinical Lipidology. 8: 336-338. DOI: 10.1016/J.Jacl.2014.02.067  0.309
2013 Wolk DA, Manning K, Kliot D, Arnold SE. Recognition memory in amnestic-mild cognitive impairment: insights from event-related potentials. Frontiers in Aging Neuroscience. 5: 89. PMID 24376418 DOI: 10.3389/Fnagi.2013.00089  0.54
2013 Steinberg SI, Negash S, Sammel MD, Bogner H, Harel BT, Livney MG, McCoubrey H, Wolk DA, Kling MA, Arnold SE. Subjective memory complaints, cognitive performance, and psychological factors in healthy older adults. American Journal of Alzheimer's Disease and Other Dementias. 28: 776-83. PMID 24363073 DOI: 10.1177/1533317513504817  0.513
2013 Motsinger-Reif AA, Zhu H, Kling MA, Matson W, Sharma S, Fiehn O, Reif DM, Appleby DH, Doraiswamy PM, Trojanowski JQ, Kaddurah-Daouk R, Arnold SE. Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer's disease from normal cognitive aging. Acta Neuropathologica Communications. 1: 28. PMID 24252434 DOI: 10.1186/2051-5960-1-28  0.443
2013 Richardson K, Schoen M, French B, Umscheid CA, Mitchell MD, Arnold SE, Heidenreich PA, Rader DJ, deGoma EM. Statins and cognitive function: a systematic review. Annals of Internal Medicine. 159: 688-97. PMID 24247674 DOI: 10.7326/0003-4819-159-10-201311190-00007  0.354
2013 Wang Z, Das SR, Xie SX, Arnold SE, Detre JA, Wolk DA. Arterial spin labeled MRI in prodromal Alzheimer's disease: A multi-site study. Neuroimage. Clinical. 2: 630-6. PMID 24179814 DOI: 10.1016/J.Nicl.2013.04.014  0.599
2013 Yarchoan M, Louneva N, Xie SX, Swenson FJ, Hu W, Soares H, Trojanowski JQ, Lee VM, Kling MA, Shaw LM, Chen-Plotkin A, Wolk DA, Arnold SE. Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease. Journal of the Neurological Sciences. 333: 9-12. PMID 23978419 DOI: 10.1016/J.Jns.2013.05.028  0.571
2013 Negash S, Wilson RS, Leurgans SE, Wolk DA, Schneider JA, Buchman AS, Bennett DA, Arnold SE. Resilient brain aging: characterization of discordance between Alzheimer's disease pathology and cognition. Current Alzheimer Research. 10: 844-51. PMID 23919768 DOI: 10.2174/15672050113109990157  0.572
2013 Irwin DJ, Cohen TJ, Grossman M, Arnold SE, McCarty-Wood E, Van Deerlin VM, Lee VM, Trojanowski JQ. Acetylated tau neuropathology in sporadic and hereditary tauopathies. The American Journal of Pathology. 183: 344-51. PMID 23885714 DOI: 10.1016/J.Ajpath.2013.04.025  0.354
2013 Arnold SE, Toledo JB, Appleby DH, Xie SX, Wang LS, Baek Y, Wolk DA, Lee EB, Miller BL, Lee VM, Trojanowski JQ. Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases. The Journal of Comparative Neurology. 521: 4339-55. PMID 23881776 DOI: 10.1002/Cne.23430  0.542
2013 Toledo JB, Arnold SE, Raible K, Brettschneider J, Xie SX, Grossman M, Monsell SE, Kukull WA, Trojanowski JQ. Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre. Brain : a Journal of Neurology. 136: 2697-706. PMID 23842566 DOI: 10.1093/Brain/Awt188  0.415
2013 Kaddurah-Daouk R, Zhu H, Sharma S, Bogdanov M, Rozen SG, Matson W, Oki NO, Motsinger-Reif AA, Churchill E, Lei Z, Appleby D, Kling MA, Trojanowski JQ, Doraiswamy PM, Arnold SE, et al. Alterations in metabolic pathways and networks in Alzheimer's disease. Translational Psychiatry. 3: e244. PMID 23571809 DOI: 10.1038/Tp.2013.18  0.409
2013 Wolk DA, Mancuso L, Kliot D, Arnold SE, Dickerson BC. Familiarity-based memory as an early cognitive marker of preclinical and prodromal AD. Neuropsychologia. 51: 1094-102. PMID 23474075 DOI: 10.1016/J.Neuropsychologia.2013.02.014  0.586
2013 Berlau DJ, Corrada MM, Robinson JL, Geser F, Arnold SE, Lee VM, Kawas CH, Trojanowski JQ. Neocortical β-amyloid area is associated with dementia and APOE in the oldest-old. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 699-705. PMID 23474043 DOI: 10.1016/J.Jalz.2012.11.011  0.401
2013 Toledo JB, Da X, Bhatt P, Wolk DA, Arnold SE, Shaw LM, Trojanowski JQ, Davatzikos C. Relationship between plasma analytes and SPARE-AD defined brain atrophy patterns in ADNI. Plos One. 8: e55531. PMID 23408997 DOI: 10.1371/Journal.Pone.0055531  0.561
2013 Seligman SC, Kamath V, Giovannetti T, Arnold SE, Moberg PJ. Olfaction and apathy in Alzheimer's disease, mild cognitive impairment, and healthy older adults. Aging & Mental Health. 17: 564-70. PMID 23398350 DOI: 10.1080/13607863.2013.768208  0.432
2013 Roalf DR, Moberg PJ, Xie SX, Wolk DA, Moelter ST, Arnold SE. Comparative accuracies of two common screening instruments for classification of Alzheimer's disease, mild cognitive impairment, and healthy aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 529-37. PMID 23260866 DOI: 10.1016/J.Jalz.2012.10.001  0.586
2013 Kling MA, Trojanowski JQ, Wolk DA, Lee VM, Arnold SE. Vascular disease and dementias: paradigm shifts to drive research in new directions. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 76-92. PMID 23183137 DOI: 10.1016/J.Jalz.2012.02.007  0.568
2013 Negash S, Xie S, Davatzikos C, Clark CM, Trojanowski JQ, Shaw LM, Wolk DA, Arnold SE. Cognitive and functional resilience despite molecular evidence of Alzheimer's disease pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: e89-95. PMID 23127468 DOI: 10.1016/J.Jalz.2012.01.009  0.612
2013 Irwin DJ, McMillan CT, Brettschneider J, Libon DJ, Powers J, Rascovsky K, Toledo JB, Boller A, Bekisz J, Chandrasekaran K, Wood EM, Shaw LM, Woo JH, Cook PA, Wolk DA, ... Arnold SE, et al. Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 84: 163-9. PMID 23117491 DOI: 10.1136/Jnnp-2012-303507  0.497
2013 Arnold SE, Vega IE, Karlawish JH, Wolk DA, Nunez J, Negron M, Xie SX, Wang LS, Dubroff JG, McCarty-Wood E, Trojanowski JQ, Van Deerlin V. Frequency and clinicopathological characteristics of presenilin 1 Gly206Ala mutation in Puerto Rican Hispanics with dementia. Journal of Alzheimer's Disease : Jad. 33: 1089-95. PMID 23114514 DOI: 10.3233/Jad-2012-121570  0.554
2013 Arnold SE, Louneva N, Cao K, Wang LS, Han LY, Wolk DA, Negash S, Leurgans SE, Schneider JA, Buchman AS, Wilson RS, Bennett DA. Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease. Neurobiology of Aging. 34: 157-68. PMID 22554416 DOI: 10.1016/J.Neurobiolaging.2012.03.004  0.603
2013 Cecchi M, Berg S, Smith C, Jicha G, Solomon P, Sadowsky C, Doraiswamy PM, Arnold S, Folley B, Casey D, Budson A. P1-131: A multicenter clinical trial to validate event-related potentials as useful biomarkers for early detection of Alzheimer's disease Alzheimer's & Dementia. 9: P197-P198. DOI: 10.1016/J.Jalz.2013.05.353  0.353
2013 Ryvkin P, Leung YY, Dragomir I, Schuck T, Schellenberg G, Arnold S, Chen-Plotkin A, Van Deerlin V, Lee V, Trojanowski J, Gregory B, Wang L. P3-064: Characterizing the Alzheimer's disease prefrontal cortex transcriptome by multiple RNA-sequencing Alzheimer's & Dementia. 9: P574-P574. DOI: 10.1016/J.Jalz.2013.05.1134  0.309
2013 Kaddurah-Daouk R, Doraiswamy PM, Zhu H, Kling M, Arnold S, Trojanowski J, Saykin A, Shen L, Kim S, Nho K, Matson W, Han X, Sharma S. Alterations in metabolic pathways and networks in mild cognitive impairment and early Alzheimer's disease Alzheimers & Dementia. 9: 571. DOI: 10.1016/J.Jalz.2013.05.1126  0.386
2013 Arnold S. F5-04-03: Molecular neuropathology in Alzheimer's disease without dementia: Focus on synapses Alzheimer's & Dementia. 9: P827-P827. DOI: 10.1016/J.Jalz.2013.04.465  0.375
2013 Kim S, Nho K, Shen L, Kling M, Han X, Zhu H, Sullivan P, Arnold S, Risacher S, Ramanan V, Doraiswamy PM, Trojanowski J, Kaddurah-Daouk R, Saykin A. Targeted lipidomic pathway-guided genetic association with Alzheimer's disease–relevant endophenotypes Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.339  0.304
2013 Leung YY, Toledo J, Nefedov A, Polikar R, Raghavan N, Xie S, Farnum M, Schultz T, Baek Y, Lobanov V, DiBernardo A, Deerlin VV, Kling M, Chen-Plotkin A, Mailman M, ... ... Arnold S, et al. Identifying multi-analyte CSF biomarkers for Alzheimer’s disease in a multi-cohort study Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.059  0.317
2012 Yarchoan M, Xie SX, Kling MA, Toledo JB, Wolk DA, Lee EB, Van Deerlin V, Lee VM, Trojanowski JQ, Arnold SE. Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias. Brain : a Journal of Neurology. 135: 3749-56. PMID 23204143 DOI: 10.1093/Brain/Aws271  0.583
2012 Trojanowski JQ, Arnold SE, Karlawish JH, Naylor M, Brunden KR, Lee VM. A model for improving the treatment and care of Alzheimer's disease patients through interdisciplinary research. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 564-73. PMID 23102127 DOI: 10.1016/J.Jalz.2011.08.005  0.377
2012 Rinne JO, Wong DF, Wolk DA, Leinonen V, Arnold SE, Buckley C, Smith A, McLain R, Sherwin PF, Farrar G, Kailajärvi M, Grachev ID. [(18)F]Flutemetamol PET imaging and cortical biopsy histopathology for fibrillar amyloid β detection in living subjects with normal pressure hydrocephalus: pooled analysis of four studies. Acta Neuropathologica. 124: 833-45. PMID 23053137 DOI: 10.1007/S00401-012-1051-Z  0.54
2012 De Jesús-Cortés HJ, Nogueras-Ortiz CJ, Gearing M, Arnold SE, Vega IE. Amphiphysin-1 protein level changes associated with tau-mediated neurodegeneration. Neuroreport. 23: 942-6. PMID 22975846 DOI: 10.1097/Wnr.0B013E32835982Ce  0.32
2012 Naylor MD, Karlawish JH, Arnold SE, Khachaturian AS, Khachaturian ZS, Lee VM, Baumgart M, Banerjee S, Beck C, Blennow K, Brookmeyer R, Brunden KR, Buckwalter KC, Comer M, Covinsky K, et al. Advancing Alzheimer's disease diagnosis, treatment, and care: recommendations from the Ware Invitational Summit. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 445-52. PMID 22959699 DOI: 10.1016/J.Jalz.2012.08.001  0.522
2012 Zhang Q, Stafford RB, Wang Z, Arnold SE, Wolk DA, Detre JA. Microvascular perfusion based on arterial spin labeled perfusion MRI as a measure of vascular risk in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 32: 677-87. PMID 22886015 DOI: 10.3233/Jad-2012-120964  0.574
2012 Hu WT, Holtzman DM, Fagan AM, Shaw LM, Perrin R, Arnold SE, Grossman M, Xiong C, Craig-Schapiro R, Clark CM, Pickering E, Kuhn M, Chen Y, Van Deerlin VM, McCluskey L, et al. Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease. Neurology. 79: 897-905. PMID 22855860 DOI: 10.1212/Wnl.0B013E318266Fa70  0.433
2012 Arnold SE, Xie SX, Leung YY, Wang LS, Kling MA, Han X, Kim EJ, Wolk DA, Bennett DA, Chen-Plotkin A, Grossman M, Hu W, Lee VM, Mackin RS, Trojanowski JQ, et al. Plasma biomarkers of depressive symptoms in older adults. Translational Psychiatry. 2: e65. PMID 22832727 DOI: 10.1038/Tp.2011.63  0.488
2012 Wolk DA, Zhang Z, Boudhar S, Clark CM, Pontecorvo MJ, Arnold SE. Amyloid imaging in Alzheimer's disease: comparison of florbetapir and Pittsburgh compound-B positron emission tomography. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 923-6. PMID 22791901 DOI: 10.1136/Jnnp-2012-302548  0.54
2012 Farlow M, Arnold SE, van Dyck CH, Aisen PS, Snider BJ, Porsteinsson AP, Friedrich S, Dean RA, Gonzales C, Sethuraman G, DeMattos RB, Mohs R, Paul SM, Siemers ER. Safety and biomarker effects of solanezumab in patients with Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 261-71. PMID 22672770 DOI: 10.1016/J.Jalz.2011.09.224  0.349
2012 Newberg AB, Arnold SE, Wintering N, Rovner BW, Alavi A. Initial clinical comparison of 18F-florbetapir and 18F-FDG PET in patients with Alzheimer disease and controls. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 902-7. PMID 22577238 DOI: 10.2967/Jnumed.111.099606  0.369
2012 Toledo JB, Brettschneider J, Grossman M, Arnold SE, Hu WT, Xie SX, Lee VM, Shaw LM, Trojanowski JQ. CSF biomarkers cutoffs: the importance of coincident neuropathological diseases. Acta Neuropathologica. 124: 23-35. PMID 22526019 DOI: 10.1007/S00401-012-0983-7  0.421
2012 Irwin DJ, McMillan CT, Toledo JB, Arnold SE, Shaw LM, Wang LS, Van Deerlin V, Lee VM, Trojanowski JQ, Grossman M. Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms. Archives of Neurology. 69: 1018-25. PMID 22490326 DOI: 10.1001/Archneurol.2012.26  0.392
2012 Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, ... Arnold SE, et al. Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. The Journal of Clinical Investigation. 122: 1316-38. PMID 22476197 DOI: 10.1172/Jci59903  0.361
2012 Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, et al. An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers. The Journal of Clinical Investigation. 122: 1339-53. PMID 22476196 DOI: 10.1172/Jci57256  0.382
2012 Patel S, Lee EB, Xie SX, Law A, Jackson EM, Arnold SE, Clark CM, Shaw LM, Grady MS, Trojanowski JQ, Hamilton RH. Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus. Fluids and Barriers of the Cns. 9: 7. PMID 22444461 DOI: 10.1186/2045-8118-9-7  0.4
2012 Irwin DJ, Cohen TJ, Grossman M, Arnold SE, Xie SX, Lee VM, Trojanowski JQ. Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies. Brain : a Journal of Neurology. 135: 807-18. PMID 22366796 DOI: 10.1093/Brain/Aws013  0.388
2012 Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, ... ... Arnold SE, et al. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proceedings of the National Academy of Sciences of the United States of America. 109: 3985-90. PMID 22343285 DOI: 10.1073/Pnas.1105829109  0.367
2012 Chin AL, Negash S, Xie S, Arnold SE, Hamilton R. Quality, and not just quantity, of education accounts for differences in psychometric performance between african americans and white non-hispanics with Alzheimer's disease. Journal of the International Neuropsychological Society : Jins. 18: 277-85. PMID 22300593 DOI: 10.1017/S1355617711001688  0.364
2012 Glass DJ, Arnold SE. Some evolutionary perspectives on Alzheimer's disease pathogenesis and pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 343-51. PMID 22137143 DOI: 10.1016/J.Jalz.2011.05.2408  0.396
2012 Musiek ES, Chen Y, Korczykowski M, Saboury B, Martinez PM, Reddin JS, Alavi A, Kimberg DY, Wolk DA, Julin P, Newberg AB, Arnold SE, Detre JA. Direct comparison of fluorodeoxyglucose positron emission tomography and arterial spin labeling magnetic resonance imaging in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 51-9. PMID 22018493 DOI: 10.1016/J.Jalz.2011.06.003  0.517
2012 Irwin D, McMillan C, Toledo J, Arnold S, Shaw L, Wang L, Lee V, Trojanowski J, Grossman M. Comparison of Cerebrospinal Fluid Levels of Tau and A 1-42 in Alzheimer's Disease and Frontotemporal Degeneration Using Two Analytical Platforms (P02.055) Neurology. 78: P02.055-P02.055. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P02.055  0.377
2012 Toledo J, Brettschneider J, Grossman M, Arnold S, Hu W, Xie S, Lee V, Shaw L, Trojanowski J. Improving Diagnostic Accuracy for Dementia: CSF Biomarker Cutoffs Based on Clinical and Neuropathological Criteria (IN3-1.010) Neurology. 78: IN3-1.010-IN3-1.010. DOI: 10.1212/Wnl.78.1_Meetingabstracts.In3-1.010  0.328
2012 Wolk D, Rinne J, Wong D, Leinonen V, Arnold S, Buckley C, Smith A, McLain R, Sherwin P, Farrar G, Kailajarvi M, Grachev I. [18F]-Flutemetamol PET Amyloid Imaging and Cortical Biopsy Histopathology in Normal Pressure Hydrocephalus: Pooled Analysis of Four Studies (IN3-1.009) Neurology. 78: IN3-1.009-IN3-1.009. DOI: 10.1212/Wnl.78.1_Meetingabstracts.In3-1.009  0.504
2012 Steinberg S, Sammel M, Livney M, Kling M, McCoubrey H, Yuen S, Arnold S. P1-128: Factors associated with cognitive resilience in late life: A three-sample comparison Alzheimer's & Dementia. 8: P150-P151. DOI: 10.1016/J.Jalz.2012.05.405  0.304
2012 Moelter S, Glenn M, Xie SX, Chittams J, Arnold S, Clark C. P1-074: The Dementia Severity Rating Scale for dementia: Relationships with the CDR sum of boxes, clinical diagnosis and CSF biomarkers Alzheimer's & Dementia. 8: P132-P132. DOI: 10.1016/J.Jalz.2012.05.350  0.391
2012 Farnum M, Baek Y, Schultz T, Nefedov A, Xie S, Leung YY, Toledo J, Raghavan N, Chen-Plotkin A, Wolk D, Polikar R, DiBernardo A, Siderowf A, Davatzikos C, Van Deerlin V, ... ... Arnold S, et al. P1-006: An integrated approach to the development of biomarkers for Alzheimer's disease using hospital population data Alzheimer's & Dementia. 8: P109-P109. DOI: 10.1016/J.Jalz.2012.05.281  0.514
2012 Arnold S, Rinne J, Wong D, Leinonen V, Wolk D, Buckley C, Smith A, McLain R, Sherwin P, Farrar G, Kailajarvi M, Grachev I. Prospective and retrospective evaluation of [18F]Flutemetamol for beta-amyloid detection in the brain of living subjects with normal pressure hydrocephalus Alzheimers & Dementia. 8: 91. DOI: 10.1016/J.Jalz.2012.05.224  0.47
2012 Leung YY, Wang L, Hu WT, Kling M, Wolk D, Trojanowski J, Lee V, Shaw L, Arnold S. P2-049: Cerebrospinal fluid biochemical biomarkers of depressive symptoms in older adults Alzheimer's & Dementia. 8: P280-P280. DOI: 10.1016/J.Jalz.2012.05.2143  0.452
2012 Jicha G, Cecchi M, Doraiswamy PM, Solomon P, Arnold S, Wolk D, Casey D, Smith C, Kulkarni M. P2-407: A multicenter clinical trial to validate Event-Related Potentials (ERPs) as useful biomarkers for early detection of Alzheimer's Alzheimer's & Dementia. 8: P406-P407. DOI: 10.1016/J.Jalz.2012.05.2032  0.506
2012 Toledo J, Yotter R, Da X, Bhatt P, Wolk D, Arnold S, Shaw L, Trojanowski J, Davatzikos C. O5-04-03: Relationship between plasma analytes and SPARE-Alzheimer's disease defined patterns of brain atrophy in ADNI Alzheimer's & Dementia. 8: P737-P738. DOI: 10.1016/J.Jalz.2012.05.1989  0.516
2012 Yarchoan M, Xie SX, Kling MA, Toledo JB, Wolk DA, Lee EB, Van Deerlin VM, Virginia ML, Trojanowski JQ, Arnold SE. S5-02-04: Relationships of cerebrovascular atherosclerosis with amyloid, tau, α-synuclein and TDP-43 pathologies in neurodegenerative disease dementias Alzheimer's & Dementia. 8: P725-P725. DOI: 10.1016/J.Jalz.2012.05.1951  0.381
2012 Moelter S, Clark C, Xie SX, Glenn M, Chittams J, Arnold S. O4-10-03: Detecting reliable change in cognitive and functional measures of mild cognitive impairment and Alzheimer's disease Alzheimer's & Dementia. 8: P634-P634. DOI: 10.1016/J.Jalz.2012.05.1691  0.385
2012 Nefedov A, Toledo J, Leung YY, Raghavan N, Xie S, Polikar R, Farnum M, Schultz T, Baek Y, Lobanov V, DiBernardo A, Narayan V, Lee V, Arnold S, Trojanowski J, et al. P3-101: Neuropathological subtypes among subjects with Alzheimer's disease Alzheimer's & Dementia. 8: P488-P488. DOI: 10.1016/J.Jalz.2012.05.1321  0.384
2011 Robinson JL, Geser F, Corrada MM, Berlau DJ, Arnold SE, Lee VM, Kawas CH, Trojanowski JQ. Neocortical and hippocampal amyloid-β and tau measures associate with dementia in the oldest-old. Brain : a Journal of Neurology. 134: 3708-15. PMID 22120149 DOI: 10.1093/Brain/Awr308  0.408
2011 Chen Y, Wolk DA, Reddin JS, Korczykowski M, Martinez PM, Musiek ES, Newberg AB, Julin P, Arnold SE, Greenberg JH, Detre JA. Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease. Neurology. 77: 1977-85. PMID 22094481 DOI: 10.1212/Wnl.0B013E31823A0Ef7  0.533
2011 Wilson RS, Boyle PA, Buchman AS, Yu L, Arnold SE, Bennett DA. Harm avoidance and risk of Alzheimer's disease. Psychosomatic Medicine. 73: 690-6. PMID 21949425 DOI: 10.1097/Psy.0B013E3182302Ale  0.38
2011 Xie SX, Baek Y, Grossman M, Arnold SE, Karlawish J, Siderowf A, Hurtig H, Elman L, McCluskey L, Van Deerlin V, Lee VM, Trojanowski JQ. Building an integrated neurodegenerative disease database at an academic health center. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: e84-93. PMID 21784346 DOI: 10.1016/J.Jalz.2010.08.233  0.365
2011 Wolk DA, Grachev ID, Buckley C, Kazi H, Grady MS, Trojanowski JQ, Hamilton RH, Sherwin P, McLain R, Arnold SE. Association between in vivo fluorine 18-labeled flutemetamol amyloid positron emission tomography imaging and in vivo cerebral cortical histopathology. Archives of Neurology. 68: 1398-403. PMID 21747004 DOI: 10.1001/Archneurol.2011.153  0.514
2011 Livney MG, Clark CM, Karlawish JH, Cartmell S, Negrón M, Nuñez J, Xie SX, Entenza-Cabrera F, Vega IE, Arnold SE. Ethnoracial differences in the clinical characteristics of Alzheimer's disease at initial presentation at an urban Alzheimer's disease center. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 19: 430-9. PMID 21522051 DOI: 10.1097/Jgp.0B013E3181F7D881  0.428
2011 Chen-Plotkin AS, Hu WT, Siderowf A, Weintraub D, Goldmann Gross R, Hurtig HI, Xie SX, Arnold SE, Grossman M, Clark CM, Shaw LM, McCluskey L, Elman L, Van Deerlin VM, Lee VM, et al. Plasma epidermal growth factor levels predict cognitive decline in Parkinson disease. Annals of Neurology. 69: 655-63. PMID 21520231 DOI: 10.1002/Ana.22271  0.328
2011 Wilson RS, Yu L, Schneider JA, Arnold SE, Buchman AS, Bennett DA. Lewy bodies and olfactory dysfunction in old age. Chemical Senses. 36: 367-73. PMID 21257733 DOI: 10.1093/Chemse/Bjq139  0.357
2011 Negash S, Bennett DA, Wilson RS, Schneider JA, Arnold SE. Cognition and neuropathology in aging: multidimensional perspectives from the Rush Religious Orders Study and Rush Memory And Aging Project. Current Alzheimer Research. 8: 336-40. PMID 21222592 DOI: 10.2174/156720511795745302  0.367
2011 Womack KB, Diaz-Arrastia R, Aizenstein HJ, Arnold SE, Barbas NR, Boeve BF, Clark CM, DeCarli CS, Jagust WJ, Leverenz JB, Peskind ER, Turner RS, Zamrini EY, Heidebrink JL, Burke JR, et al. Temporoparietal hypometabolism in frontotemporal lobar degeneration and associated imaging diagnostic errors. Archives of Neurology. 68: 329-37. PMID 21059987 DOI: 10.1001/Archneurol.2010.295  0.352
2011 Wang H, Stucky A, Hahn C, Wilson R, Bennett D, Arnold S. BDNF-trkB signaling in late life cognitive decline and Alzheimer’s disease Translational Neuroscience. 2. DOI: 10.2478/S13380-011-0015-4  0.352
2011 Talbot K, Wang H, Bakshi K, Trojanowski J, Arnold S. P4-441: The diabetes drug liraglutide ameliorates insulin resistance in the hippocampal formation of Alzheimer's disease (AD) cases Alzheimer's & Dementia. 7: e65-e65. DOI: 10.1016/J.Jalz.2011.09.137  0.339
2011 Negash S, Xie SX, Davatzikos C, Wolk D, Arnold S. P2-053: Factors associated with cognitive and functional resilience despite molecular evidence of Alzheimer's disease pathology Alzheimer's & Dementia. 7: S324-S324. DOI: 10.1016/J.Jalz.2011.05.942  0.581
2011 Arnold S, Xie SX, Leung Y, Kim E, Kling M, Wilson R, Bennett D, Hu W, Mackin S, Grossman M, Chen-Plotkin A, Wolk D, Lee V, Trojanowski J, Shaw L. P2-017: Biochemical Biomarkers of Depressive Symptoms in ADNI Alzheimer's & Dementia. 7: S312-S312. DOI: 10.1016/J.Jalz.2011.05.907  0.446
2011 Negash S, Chin A, Xie S, Arnold S, Hamilton R. P1-450: Quality, and not just quantity, of education accounts for ethnoracial differences in neuropsychological performance in Alzheimer's disease Alzheimer's & Dementia. 7: S257-S258. DOI: 10.1016/J.Jalz.2011.05.732  0.341
2011 Hu WT, Holtzman D, Clark C, Grossman M, Karlawish J, Fagan A, Lee V, Swenson F, Craig-Schapiro R, Perrin RJ, Soares H, Trojanowski J, Xiong C, Morris J, Shaw L, ... Arnold S, et al. P1-089: Plasma multianalyte profiling of mild cognitive impairment and Alzheimer's disease in two academic centers and the Alzheimer's Disease Neuroimaging Initiative Alzheimer's & Dementia. 7: S138-S138. DOI: 10.1016/J.Jalz.2011.05.368  0.43
2011 Wolk D, Grachev I, Buckley C, Heurling K, Hamilton R, Arnold S. [18F]-Flutemetamol amyloid PET imaging in patients with normal pressure hydrocephalus Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2099  0.459
2011 Talbot K, Wang H, Kazi H, Han L, Bakshi K, Wilson R, Schneider J, Bennett D, Wolf B, Trojanowski J, Arnold S. O4-02-01: Brain insulin resistance demonstrated in Alzheimer's disease is closely associated with elevated IRS-1 pS and cognitive deficits Alzheimer's & Dementia. 7: S683-S683. DOI: 10.1016/J.Jalz.2011.05.1972  0.366
2011 Steinberg S, Livney M, Kling M, McCoubrey H, Yuen S, Edwards C, Xie SX, Arnold S. P3-279: Predictors of resilient cognitive aging: Baseline characteristics Alzheimer's & Dementia. 7: S605-S606. DOI: 10.1016/J.Jalz.2011.05.1721  0.317
2011 Bilello M, Doshi J, Xie S, Arnold S, Davatzikos C. IC-P-032: Association of brain atrophy and vascular white matter lesions with CERAD score in Alzheimer's disease Alzheimer's & Dementia. 7: S21-S21. DOI: 10.1016/J.Jalz.2011.05.048  0.309
2010 Gabel MJ, Foster NL, Heidebrink JL, Higdon R, Aizenstein HJ, Arnold SE, Barbas NR, Boeve BF, Burke JR, Clark CM, Dekosky ST, Farlow MR, Jagust WJ, Kawas CH, Koeppe RA, et al. Validation of consensus panel diagnosis in dementia. Archives of Neurology. 67: 1506-12. PMID 21149812 DOI: 10.1001/Archneurol.2010.301  0.32
2010 Hu WT, Chen-Plotkin A, Grossman M, Arnold SE, Clark CM, Shaw LM, McCluskey L, Elman L, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Novel CSF biomarkers for frontotemporal lobar degenerations. Neurology. 75: 2079-86. PMID 21048198 DOI: 10.1016/J.Jalz.2010.05.253  0.333
2010 Geser F, Robinson JL, Malunda JA, Xie SX, Clark CM, Kwong LK, Moberg PJ, Moore EM, Van Deerlin VM, Lee VM, Arnold SE, Trojanowski JQ. Pathological 43-kDa transactivation response DNA-binding protein in older adults with and without severe mental illness. Archives of Neurology. 67: 1238-50. PMID 20937952 DOI: 10.1001/Archneurol.2010.254  0.365
2010 Hamilton R, Patel S, Lee EB, Jackson EM, Lopinto J, Arnold SE, Clark CM, Basil A, Shaw LM, Xie SX, Grady MS, Trojanowski JQ. Lack of shunt response in suspected idiopathic normal pressure hydrocephalus with Alzheimer disease pathology. Annals of Neurology. 68: 535-40. PMID 20687117 DOI: 10.1002/Ana.22015  0.425
2010 Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, McCluskey L, Elman L, Karlawish J, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Biomarker discovery for Alzheimer's disease, frontotemporal lobar degeneration, and Parkinson's disease. Acta Neuropathologica. 120: 385-99. PMID 20652578 DOI: 10.1007/S00401-010-0723-9  0.45
2010 Arnold SE, Lee EB, Moberg PJ, Stutzbach L, Kazi H, Han LY, Lee VM, Trojanowski JQ. Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease. Annals of Neurology. 67: 462-9. PMID 20437581 DOI: 10.1002/Ana.21910  0.39
2010 Trojanowski JQ, Arnold SE, Karlawish JH, Brunden K, Cary M, Davatzikos C, Detre J, Gaulton G, Grossman M, Hurtig H, Jedrziewski K, McCluskey L, Naylor M, Polsky D, Schellenberg GD, et al. Design of comprehensive Alzheimer's disease centers to address unmet national needs. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 150-5. PMID 20298979 DOI: 10.1016/J.Jalz.2009.11.004  0.399
2010 Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, Pickering E, Kuhn M, Chen Y, McCluskey L, Elman L, Karlawish J, Hurtig HI, Siderowf A, Lee VM, et al. Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment. Acta Neuropathologica. 119: 669-78. PMID 20232070 DOI: 10.1007/S00401-010-0667-0  0.442
2010 Berlau DJ, Corrada MM, Robinson J, Geser F, Arnold S, Lee VM, Kawas CH, Trojanowski JQ. O3-01-06: Neocortical beta-amyloid area, but not CERAD plaque stage, is associated with dementia status and Apolipoprotein E (APOE) genotype in the oldest old Alzheimer's & Dementia. 6: S125-S126. DOI: 10.1016/J.Jalz.2010.05.394  0.304
2009 Xie SX, Ewbank DC, Chittams J, Karlawish JH, Arnold SE, Clark CM. Rate of decline in Alzheimer disease measured by a Dementia Severity Rating Scale. Alzheimer Disease and Associated Disorders. 23: 268-74. PMID 19812470 DOI: 10.1097/Wad.0B013E318194A324  0.382
2009 Wilson RS, Arnold SE, Schneider JA, Boyle PA, Buchman AS, Bennett DA. Olfactory impairment in presymptomatic Alzheimer's disease. Annals of the New York Academy of Sciences. 1170: 730-5. PMID 19686220 DOI: 10.1111/J.1749-6632.2009.04013.X  0.465
2009 Moelter ST, Davatzikos C, Moberg PJ, Koka D, Shaw LM, Trojanowski JQ, Arnold SE, Karlawish JH, Clark CM. O4-05-01: Cognitive performance characteristics of individuals with normal or pathological CSF and MRI biomarkers of Alzheimer's disease Alzheimer's & Dementia. 5: P159-P159. DOI: 10.1016/J.Jalz.2009.05.549  0.411
2008 Louneva N, Cohen JW, Han LY, Talbot K, Wilson RS, Bennett DA, Trojanowski JQ, Arnold SE. Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease. The American Journal of Pathology. 173: 1488-95. PMID 18818379 DOI: 10.2353/Ajpath.2008.080434  0.376
2008 Wilson RS, Arnold SE, Buchman AS, Tang Y, Bennett DA. Odor identification and progression of parkinsonian signs in older persons. Experimental Aging Research. 34: 173-87. PMID 18568978 DOI: 10.1080/03610730802070001  0.342
2008 Xie SX, Forman MS, Farmer J, Moore P, Wang Y, Wang X, Clark CM, Coslett HB, Chatterjee A, Arnold SE, Rosen H, Karlawish JH, Van Deerlin VM, Lee VM, Trojanowski JQ, et al. Factors associated with survival probability in autopsy-proven frontotemporal lobar degeneration. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 126-9. PMID 17615171 DOI: 10.1136/Jnnp.2006.110288  0.339
2008 Cartmell SP, Xie SX, Martinez P, Nunez J, Janis P, Baek Y, Karlawish JHT, Arnold SE, Clark CM. P3-007: Instability of a diagnosis of mild cognitive impairment based on a brief screening assessment of English- and Spanish-speaking individuals in a general care clinic Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1570  0.32
2007 Wilson RS, Schneider JA, Arnold SE, Bienias JL, Bennett DA. Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment. Archives of General Psychiatry. 64: 1204-12. PMID 17909133 DOI: 10.1001/Archpsyc.64.10.1204  0.406
2007 Foster NL, Heidebrink JL, Clark CM, Jagust WJ, Arnold SE, Barbas NR, DeCarli CS, Turner RS, Koeppe RA, Higdon R, Minoshima S. FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease. Brain : a Journal of Neurology. 130: 2616-35. PMID 17704526 DOI: 10.1093/Brain/Awm177  0.345
2007 Nakashima-Yasuda H, Uryu K, Robinson J, Xie SX, Hurtig H, Duda JE, Arnold SE, Siderowf A, Grossman M, Leverenz JB, Woltjer R, Lopez OL, Hamilton R, Tsuang DW, Galasko D, et al. Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases. Acta Neuropathologica. 114: 221-9. PMID 17653732 DOI: 10.1007/S00401-007-0261-2  0.404
2007 Wilson RS, Schneider JA, Arnold SE, Tang Y, Boyle PA, Bennett DA. Olfactory identification and incidence of mild cognitive impairment in older age. Archives of General Psychiatry. 64: 802-8. PMID 17606814 DOI: 10.1001/Archpsyc.64.7.802  0.39
2007 Wilson RS, Schneider JA, Boyle PA, Arnold SE, Tang Y, Bennett DA. Chronic distress and incidence of mild cognitive impairment. Neurology. 68: 2085-92. PMID 17562829 DOI: 10.1212/01.Wnl.0000264930.97061.82  0.334
2007 Wilson RS, Arnold SE, Schneider JA, Li Y, Bennett DA. Chronic distress, age-related neuropathology, and late-life dementia. Psychosomatic Medicine. 69: 47-53. PMID 17244848 DOI: 10.1097/01.Psy.0000250264.25017.21  0.389
2007 Wilson RS, Arnold SE, Schneider JA, Tang Y, Bennett DA. The relationship between cerebral Alzheimer's disease pathology and odour identification in old age. Journal of Neurology, Neurosurgery, and Psychiatry. 78: 30-5. PMID 17012338 DOI: 10.1136/Jnnp.2006.099721  0.347
2006 Arvanitakis Z, Schneider JA, Wilson RS, Li Y, Arnold SE, Wang Z, Bennett DA. Diabetes is related to cerebral infarction but not to AD pathology in older persons. Neurology. 67: 1960-5. PMID 17159101 DOI: 10.1212/01.Wnl.0000247053.45483.4E  0.387
2006 Moberg PJ, Arnold SE, Doty RL, Gur RE, Balderston CC, Roalf DR, Gur RC, Kohler CG, Kanes SJ, Siegel SJ, Turetsky BI. Olfactory functioning in schizophrenia: relationship to clinical, neuropsychological, and volumetric MRI measures. Journal of Clinical and Experimental Neuropsychology. 28: 1444-61. PMID 17050269 DOI: 10.1080/13803390500434409  0.312
2006 Wilson RS, Arnold SE, Schneider JA, Kelly JF, Tang Y, Bennett DA. Chronic psychological distress and risk of Alzheimer's disease in old age. Neuroepidemiology. 27: 143-53. PMID 16974109 DOI: 10.1159/000095761  0.45
2006 Forman MS, Farmer J, Johnson JK, Clark CM, Arnold SE, Coslett HB, Chatterjee A, Hurtig HI, Karlawish JH, Rosen HJ, Van Deerlin V, Lee VM, Miller BL, Trojanowski JQ, Grossman M. Frontotemporal dementia: clinicopathological correlations. Annals of Neurology. 59: 952-62. PMID 16718704 DOI: 10.1002/Ana.20873  0.409
2006 Bennett DA, Schneider JA, Tang Y, Arnold SE, Wilson RS. The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study. The Lancet. Neurology. 5: 406-12. PMID 16632311 DOI: 10.1016/S1474-4422(06)70417-3  0.353
2006 Wilson RS, Arnold SE, Tang Y, Bennett DA. Odor identification and decline in different cognitive domains in old age. Neuroepidemiology. 26: 61-7. PMID 16352908 DOI: 10.1159/000090250  0.324
2006 Leung YY, Chou Y, Arnold SE, Trojanowski JQ, Schellenberg GD, Wang L. P2-279: CSF SMALL RNA BIOMARKERS FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P785-P786. DOI: 10.1016/J.Jalz.2018.06.968  0.342
2006 Carlyle BC, Leslie S, Trombetta BA, Nobuhara CK, van Dyck CH, Nairn AC, Arnold SE. P1-274: A TARGETED MASS-SPECTROMETRY METHOD FOR QUANTIFICATION OF CEREBROSPINAL FLUID BIOMARKERS OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P387-P387. DOI: 10.1016/J.Jalz.2018.06.280  0.339
2006 Arnold SE, Soetanto A, Chea H, Schneider JA, Bennett DA, Wilson RS. P1-396: Neuropathological investigations of chronic psychological distress and its correlation with cognitive impairment in the elderly Alzheimer's & Dementia. 2: S214-S214. DOI: 10.1016/J.Jalz.2006.05.774  0.332
2006 Talbot K, Han L, Schneider JA, Wilson RS, Bennett DA, Arnold SE. O3-02-02: Expression of pIRS-1 (S312 and S616) is elevated in MCI and AD and correlates with cognitive impairment and neurofibrillary pathology Alzheimer's & Dementia. 2: S54-S54. DOI: 10.1016/J.Jalz.2006.05.197  0.393
2005 Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE. Education modifies the association of amyloid but not tangles with cognitive function. Neurology. 65: 953-5. PMID 16186546 DOI: 10.1212/01.Wnl.0000176286.17192.69  0.382
2005 Bennett DA, Schneider JA, Wilson RS, Bienias JL, Berry-Kravis E, Arnold SE. Amyloid mediates the association of apolipoprotein E e4 allele to cognitive function in older people. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 1194-9. PMID 16107349 DOI: 10.1136/Jnnp.2004.054445  0.317
2005 Sunderland T, Gur RE, Arnold SE. The use of biomarkers in the elderly: current and future challenges. Biological Psychiatry. 58: 272-6. PMID 16018985 DOI: 10.1016/J.Biopsych.2005.05.016  0.356
2005 Francis PT, Nordberg A, Arnold SE. A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease? Trends in Pharmacological Sciences. 26: 104-11. PMID 15681028 DOI: 10.1016/J.Tips.2004.12.010  0.403
2005 Bodner SM, Berrettini W, van Deerlin V, Bennett DA, Wilson RS, Trojanowski JQ, Arnold SE. Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 134: 1-5. PMID 15635706 DOI: 10.1002/Ajmg.B.30154  0.354
2004 Cairns NJ, Grossman M, Arnold SE, Burn DJ, Jaros E, Perry RH, Duyckaerts C, Stankoff B, Pillon B, Skullerud K, Cruz-Sanchez FF, Bigio EH, Mackenzie IR, Gearing M, Juncos JL, et al. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease. Neurology. 63: 1376-84. PMID 15505152 DOI: 10.1212/01.Wnl.0000139809.16817.Dd  0.355
2004 Cairns NJ, Uryu K, Bigio EH, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Arnold SE, Lee VM, Trojanowski JQ. alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases. Acta Neuropathologica. 108: 213-23. PMID 15170578 DOI: 10.1007/S00401-004-0882-7  0.318
2004 Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE. Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. Archives of Neurology. 61: 378-84. PMID 15023815 DOI: 10.1001/Archneur.61.3.378  0.44
2004 Bennett DA, Wilson RS, Schneider JA, Bienias JL, Arnold SE. Cerebral infarctions and the relationship of depression symptoms to level of cognitive functioning in older persons. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 12: 211-9. PMID 15010350 DOI: 10.1097/00019442-200403000-00012  0.337
2004 Higdon R, Foster NL, Koeppe RA, DeCarli CS, Jagust WJ, Clark CM, Barbas NR, Arnold SE, Turner RS, Heidebrink JL, Minoshima S. A comparison of classification methods for differentiating fronto-temporal dementia from Alzheimer's disease using FDG-PET imaging. Statistics in Medicine. 23: 315-26. PMID 14716732 DOI: 10.1002/Sim.1719  0.365
2004 Bodner SM, Arnold S, Berrettini W. P4-089 Population based case control association study of the brain-derived neurotrophic factor gene in Alzheimer's disease Neurobiology of Aging. 25: S499. DOI: 10.1016/S0197-4580(04)81647-6  0.346
2004 Foster NL, Barbas NR, Heidebrink JL, Scott Turner R, Clark CM, Jagust WJ, Arnold SE, DeCarli CS, Koeppe RA, Higdon R. P3-070 Adding FDG-PET to clinical history and examination improves the accuracy of dementia diagnosis Neurobiology of Aging. 25: S372. DOI: 10.1016/S0197-4580(04)81222-3  0.353
2004 Heidebrink JL, Barbas NR, Scott Turner R, Clark CM, Jagust WJ, Arnold SE, DeCarli CS, Koeppe RA, Higdon R, Foster NL. P3-065 FDG-PET improves differential diagnosis of dementia when clinical history and examination are ambiguous Neurobiology of Aging. 25: S370-S371. DOI: 10.1016/S0197-4580(04)81217-X  0.302
2004 Bennett DA, Schneider JA, Wilson RS, Bienias JL, Berry-Kravis E, Arnold SE. P2-271 Amyloid mediates the association of apolipoprotein E ε4 allele to cognitive function in older persons Neurobiology of Aging. 25: S309. DOI: 10.1016/S0197-4580(04)81016-9  0.346
2004 Clark CM, Xie S, Chittams J, Karlawish J, Arnold SE, Ewbank DC. P1-015 The dementia severity rating scale, a knowledgeable informant measure of dementia symptom severity, provides a reliable and clinically efficient measure of Alzheimer's disease progression from the time of initial evaluation to the severe impairment stage Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80329-4  0.373
2003 Turetsky BI, Moberg PJ, Roalf DR, Arnold SE, Gur RE. Decrements in volume of anterior ventromedial temporal lobe and olfactory dysfunction in schizophrenia. Archives of General Psychiatry. 60: 1193-200. PMID 14662551 DOI: 10.1001/Archpsyc.60.12.1193  0.309
2003 Lowery N, Giovanni L, Mozley LH, Arnold SE, Bilker WB, Gur RE, Moberg PJ. Relationship between clock-drawing and neuropsychological and functional status in elderly institutionalized patients with schizophrenia. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 11: 621-8. PMID 14609802 DOI: 10.1176/Appi.Ajgp.11.6.621  0.364
2003 Wilson RS, Schneider JA, Bienias JL, Arnold SE, Evans DA, Bennett DA. Depressive symptoms, clinical AD, and cortical plaques and tangles in older persons. Neurology. 61: 1102-7. PMID 14581672 DOI: 10.1212/01.Wnl.0000092914.04345.97  0.391
2003 Falke E, Nissanov J, Mitchell TW, Bennett DA, Trojanowski JQ, Arnold SE. Subicular dendritic arborization in Alzheimer's disease correlates with neurofibrillary tangle density. The American Journal of Pathology. 163: 1615-21. PMID 14507668 DOI: 10.1016/S0002-9440(10)63518-3  0.342
2003 Bennett DA, Wilson RS, Schneider JA, Evans DA, Mendes de Leon CF, Arnold SE, Barnes LL, Bienias JL. Education modifies the relation of AD pathology to level of cognitive function in older persons. Neurology. 60: 1909-15. PMID 12821732 DOI: 10.1212/01.Wnl.0000069923.64550.9F  0.388
2003 Schneider JA, Wilson RS, Cochran EJ, Bienias JL, Arnold SE, Evans DA, Bennett DA. Relation of cerebral infarctions to dementia and cognitive function in older persons. Neurology. 60: 1082-8. PMID 12682310 DOI: 10.1212/01.Wnl.0000055863.87435.B2  0.343
2003 Bennett DA, Wilson RS, Schneider JA, Evans DA, Aggarwal NT, Arnold SE, Cochran EJ, Berry-Kravis E, Bienias JL. Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease. Neurology. 60: 246-52. PMID 12552039 DOI: 10.1212/01.Wnl.0000042478.08543.F7  0.426
2002 Wilson RS, Barnes LL, Mendes de Leon CF, Aggarwal NT, Schneider JS, Bach J, Pilat J, Beckett LA, Arnold SE, Evans DA, Bennett DA. Depressive symptoms, cognitive decline, and risk of AD in older persons. Neurology. 59: 364-70. PMID 12177369 DOI: 10.1212/Wnl.59.3.364  0.359
2002 McBride T, Moberg PJ, Arnold SE, Mozley LH, Mahr RN, Gibney M, Kumar A, Gur RE. Neuropsychological functioning in elderly patients with schizophrenia and Alzheimer's disease. Schizophrenia Research. 55: 217-27. PMID 12048145 DOI: 10.1016/S0920-9964(01)00232-8  0.397
2002 Mitchell TW, Mufson EJ, Schneider JA, Cochran EJ, Nissanov J, Han LY, Bienias JL, Lee VM, Trojanowski JQ, Bennett DA, Arnold SE. Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease. Annals of Neurology. 51: 182-9. PMID 11835374 DOI: 10.1002/Ana.10086  0.443
2001 Kurtz MM, Moberg PJ, Mozley LH, Hickey T, Arnold SE, Bilker WB, Gur RE. Cognitive impairment and functional status in elderly institutionalized patients with schizophrenia. International Journal of Geriatric Psychiatry. 16: 631-8. PMID 11424173 DOI: 10.1002/Gps.394  0.375
2001 Arnold SE. Contributions of neuropathology to understanding schizophrenia in late life. Harvard Review of Psychiatry. 9: 69-76. PMID 11266404 DOI: 10.1080/10673220127882  0.33
2001 Zhukareva V, Vogelsberg-Ragaglia V, Van Deerlin VM, Bruce J, Shuck T, Grossman M, Clark CM, Arnold SE, Masliah E, Galasko D, Trojanowski JQ, Lee VM. Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia. Annals of Neurology. 49: 165-75. PMID 11220736 DOI: 10.1002/1531-8249(20010201)49:2<165::Aid-Ana36>3.0.Co;2-3  0.349
2000 Arnold SE, Han LY, Clark CM, Grossman M, Trojanowski JQ. Quantitative neurohistological features of frontotemporal degeneration. Neurobiology of Aging. 21: 913-9. PMID 11124442 DOI: 10.1016/S0197-4580(00)00173-1  0.383
2000 Mitchell TW, Nissanov J, Han LY, Mufson EJ, Schneider JA, Cochran EJ, Bennett DA, Lee VM, Trojanowski JQ, Arnold SE. Novel method to quantify neuropil threads in brains from elders with or without cognitive impairment. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 48: 1627-38. PMID 11101631 DOI: 10.1177/002215540004801206  0.435
2000 Arnold SE. Part III. Neuropathology of Alzheimer's disease. Disease-a-Month : Dm. 46: 687-705. PMID 11078010 DOI: 10.1016/S0011-5029(00)90030-0  0.391
2000 Hurtig HI, Trojanowski JQ, Galvin J, Ewbank D, Schmidt ML, Lee VM, Clark CM, Glosser G, Stern MB, Gollomp SM, Arnold SE. Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's disease. Neurology. 54: 1916-21. PMID 10822429 DOI: 10.1212/Wnl.54.10.1916  0.327
2000 Falke E, Han LY, Arnold SE. Absence of neurodegeneration in the thalamus and caudate of elderly patients with schizophrenia. Psychiatry Research. 93: 103-10. PMID 10725527 DOI: 10.1016/S0165-1781(00)00104-9  0.371
1999 Arnold SE. Cognition and neuropathology in schizophrenia. Acta Psychiatrica Scandinavica. Supplementum. 395: 41-50. PMID 10225332 DOI: 10.1111/J.1600-0447.1999.Tb05982.X  0.319
1998 Arnold SE, Smutzer GS, Trojanowski JQ, Moberg PJ. Cellular and molecular neuropathology of the olfactory epithelium and central olfactory pathways in Alzheimer's disease and schizophrenia. Annals of the New York Academy of Sciences. 855: 762-75. PMID 9929682 DOI: 10.1111/J.1749-6632.1998.Tb10656.X  0.352
1998 Davies P, Resnick J, Resnick B, Gilman S, Growdon JH, Khachaturian ZS, Radebaugh TS, Roses AD, Selkoe DJ, Trojanowski JQ, Blass JP, Gibson GE, Sheu KFR, Blennow K, Delacourte A, ... ... Arnold SE, et al. Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease' Neurobiology of Aging. 19: 109-116. PMID 9558143 DOI: 10.1016/S0197-4580(98)00022-0  0.402
1998 Arnold SE, Trojanowski JQ, Gur RE, Blackwell P, Han LY, Choi C. Absence of neurodegeneration and neural injury in the cerebral cortex in a sample of elderly patients with schizophrenia. Archives of General Psychiatry. 55: 225-32. PMID 9510216 DOI: 10.1001/Archpsyc.55.3.225  0.369
1997 Trojanowski JQ, Clark CM, Schmidt ML, Arnold SE, Lee VM. Strategies for improving the postmortem neuropathological diagnosis of Alzheimer's disease. Neurobiology of Aging. 18: S75-9. PMID 9330990 DOI: 10.1016/S0197-4580(97)00075-4  0.438
1997 Moberg PJ, Doty RL, Mahr RN, Mesholam RI, Arnold SE, Turetsky BI, Gur RE. Olfactory identification in elderly schizophrenia and Alzheimer's disease. Neurobiology of Aging. 18: 163-7. PMID 9258893 DOI: 10.1016/S0197-4580(97)00015-8  0.412
1997 Prohovnik I, Arnold SE, Smith G, Lucas LR. Physostigmine reversal of scopolamine-induced hypofrontality. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 220-8. PMID 9040502 DOI: 10.1097/00004647-199702000-00012  0.363
1996 Arnold SE, Trojanowski JQ. Recent advances in defining the neuropathology of schizophrenia. Acta Neuropathologica. 92: 217-31. PMID 8870823 DOI: 10.1007/S004010050512  0.318
1996 Arnold SE, Franz BR, Trojanowski JQ, Moberg PJ, Gur RE. Glial fibrillary acidic protein-immunoreactive astrocytosis in elderly patients with schizophrenia and dementia. Acta Neuropathologica. 91: 269-77. PMID 8834539 DOI: 10.1007/S004010050425  0.385
1996 Arnold SE, Trojanowski JQ. Cognitive impairment in elderly schizophrenia: a dementia (still) lacking distinctive histopathology. Schizophrenia Bulletin. 22: 5-9. PMID 8685663 DOI: 10.1093/Schbul/22.1.5  0.398
1995 Martinoli MG, Trojanowski JQ, Schmidt ML, Arnold SE, Fujiwara TM, Lee VM, Hurtig H, Julien JP, Clark C. Association of apolipoprotein epsilon 4 allele and neuropathologic findings in patients with dementia. Acta Neuropathologica. 90: 239-43. PMID 8525796 DOI: 10.1007/Bf00296506  0.391
1994 Arnold SE, Hyman BT, Van Hoesen GW. Neuropathologic changes of the temporal pole in Alzheimer's disease and Pick's disease. Archives of Neurology. 51: 145-50. PMID 8304839 DOI: 10.1001/Archneur.1994.00540140051014  0.382
1994 Arnold SE, Franz BR, Trojanowski JQ. Elderly patients with schizophrenia exhibit infrequent neurodegenerative lesions. Neurobiology of Aging. 15: 299-303. PMID 7936053 DOI: 10.1016/0197-4580(94)90024-8  0.41
1994 Holdnack JA, Moberg PJ, Arnold SE, Gur RE, Gur RC. MMPI characteristics in adults diagnosed with ADD: a preliminary report. The International Journal of Neuroscience. 79: 47-58. PMID 7744550 DOI: 10.3109/00207459408986066  0.301
1991 Hyman BT, Flory JE, Arnold SE, Van Hoesen GW, Schelper RL, Ghanbari H, Haigler H. Quantitative assessment of ALZ-50 immunoreactivity in Alzheimer's disease. Journal of Geriatric Psychiatry and Neurology. 4: 231-5. PMID 1789912 DOI: 10.1177/089198879100400410  0.36
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