| Year |
Citation |
Score |
| 2022 |
Woller SA, Ruschel J, Morquette B, Cardia J, Yan D, Holton K, Shmushkovich T, Niederst E, Bulock K, Wolfson A, Abbinanti M, Fournier AE, McKerracher L, Rosen KM. Self-delivering RNAi compounds as therapeutic agents in the central nervous system to enhance axonal regeneration after injury. Iscience. 25: 104379. PMID 35620420 DOI: 10.1016/j.isci.2022.104379 |
0.566 |
|
| 2021 |
Fehlings MG, Chen Y, Aarabi B, Ahmad FU, Anderson KD, Dumont T, Fourney DR, Harrop JS, Kim KD, Kwon BK, Lingman H, Rizzo M, Shih L, Tsai E, Vaccaro A, ... McKerracher L, et al. A Randomized Controlled Trial of Local Delivery of a Rho-Inhibitor (VX-210) in Patients With Acute Traumatic Cervical Spinal Cord Injury. Journal of Neurotrauma. PMID 33559524 DOI: 10.1089/neu.2020.7096 |
0.333 |
|
| 2018 |
Fehlings MG, Kim KD, Aarabi B, Rizzo M, Bond LM, McKerracher L, Vaccaro A, Okonkwo DO. Rho Inhibitor VX-210 in Acute Traumatic Subaxial Cervical Spinal Cord Injury: Design of the SPinal Cord Injury Rho INhibition InvestiGation (SPRING) Clinical Trial. Journal of Neurotrauma. PMID 29316845 DOI: 10.1089/Neu.2017.5434 |
0.44 |
|
| 2015 |
McKerracher L, Rosen KM. MAG, myelin and overcoming growth inhibition in the CNS. Frontiers in Molecular Neuroscience. 8: 51. PMID 26441514 DOI: 10.3389/Fnmol.2015.00051 |
0.582 |
|
| 2015 |
McKerracher L, Rosen KM. MAG, myelin and overcoming growth inhibition in the CNS Frontiers in Molecular Neuroscience. 8. DOI: 10.3389/fnmol.2015.00051 |
0.378 |
|
| 2014 |
Bond LM, McKerracher L. Cervical spinal cord injury: tailoring clinical trial endpoints to reflect meaningful functional improvements. Neural Regeneration Research. 9: 1493-7. PMID 25317162 DOI: 10.4103/1673-5374.139470 |
0.33 |
|
| 2013 |
McKerracher L, Anderson KD. Analysis of recruitment and outcomes in the phase I/IIa Cethrin clinical trial for acute spinal cord injury. Journal of Neurotrauma. 30: 1795-804. PMID 23844986 DOI: 10.1089/Neu.2013.2909 |
0.331 |
|
| 2013 |
McKerracher L, Guertin P. Rho as a target to promote repair: translation to clinical studies with cethrin. Current Pharmaceutical Design. 19: 4400-10. PMID 23360272 DOI: 10.2174/1381612811319240007 |
0.525 |
|
| 2012 |
McKerracher L, Ferraro GB, Fournier AE. Rho signaling and axon regeneration. International Review of Neurobiology. 105: 117-40. PMID 23206598 DOI: 10.1016/B978-0-12-398309-1.00007-X |
0.706 |
|
| 2011 |
Fehlings MG, Theodore N, Harrop J, Maurais G, Kuntz C, Shaffrey CI, Kwon BK, Chapman J, Yee A, Tighe A, McKerracher L. A phase I/IIa clinical trial of a recombinant Rho protein antagonist in acute spinal cord injury. Journal of Neurotrauma. 28: 787-96. PMID 21381984 DOI: 10.1089/Neu.2011.1765 |
0.356 |
|
| 2010 |
Fehlings MG, Theodore N, Harrop JS, Maurais G, Kuntz C, Shaffrey CI, Kwon B, Chapman J, Tighe A, McKerracher L. A Phase I/IIa Clinical Trial of a Recombinant Rho Protein Antagonist in Patients With Complete Cervical and Thoracic Spinal Cord Injuries Neurosurgery. 67: 545-546. DOI: 10.1227/01.Neu.0000387001.04626.C6 |
0.363 |
|
| 2009 |
Mckerracher L, Julien JP, Aguayo AJ. Role of cellular interactions in axonal growth and regeneration The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0029 |
0.657 |
|
| 2008 |
Lord-Fontaine S, Yang F, Diep Q, Dergham P, Munzer S, Tremblay P, McKerracher L. Local inhibition of Rho signaling by cell-permeable recombinant protein BA-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury. Journal of Neurotrauma. 25: 1309-22. PMID 19061375 DOI: 10.1089/Neu.2008.0613 |
0.769 |
|
| 2008 |
Ruff RL, McKerracher L, Selzer ME. Repair and neurorehabilitation strategies for spinal cord injury. Annals of the New York Academy of Sciences. 1142: 1-20. PMID 18990118 DOI: 10.1196/annals.1444.004 |
0.556 |
|
| 2007 |
Bertrand J, Di Polo A, McKerracher L. Enhanced survival and regeneration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists. Neurobiology of Disease. 25: 65-72. PMID 17011202 DOI: 10.1016/J.Nbd.2006.08.008 |
0.538 |
|
| 2007 |
Fehlings M, Theodore N, Harrop J, Maurais G, Kuntz C, Shaffrey C, Kwon B, Chapman J, Yee A, Tremblay P, McKerracher L. P166. The Cethrin Phase I/IIa Prospective Clinical Trial of a Cethrin for the Treatment of Acute Spinal Cord Injury The Spine Journal. 7: 159S. DOI: 10.1016/J.Spinee.2007.07.376 |
0.348 |
|
| 2006 |
McKerracher L, Higuchi H. Targeting Rho to stimulate repair after spinal cord injury. Journal of Neurotrauma. 23: 309-17. PMID 16629618 DOI: 10.1310/5Na7-Mbgu-Q2Tu-N41Q |
0.543 |
|
| 2006 |
Lasko D, McKerracher L. Fluorescent assay of cell-permeable C3 transferase activity. Methods in Enzymology. 406: 512-20. PMID 16472683 DOI: 10.1016/S0076-6879(06)06039-3 |
0.316 |
|
| 2006 |
Dubreuil CI, Marklund N, Deschamps K, McIntosh TK, McKerracher L. Activation of Rho after traumatic brain injury and seizure in rats. Experimental Neurology. 198: 361-9. PMID 16448651 DOI: 10.1016/J.Expneurol.2005.12.002 |
0.387 |
|
| 2005 |
Bertrand J, Winton MJ, Rodriguez-Hernandez N, Campenot RB, McKerracher L. Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1113-21. PMID 15689547 DOI: 10.1523/Jneurosci.3931-04.2005 |
0.822 |
|
| 2004 |
McKerracher L, David S. Easing the brakes on spinal cord repair. Nature Medicine. 10: 1052-3. PMID 15459707 DOI: 10.1038/Nm1004-1052 |
0.748 |
|
| 2003 |
Dubreuil CI, Winton MJ, McKerracher L. Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. The Journal of Cell Biology. 162: 233-43. PMID 12860969 DOI: 10.1083/Jcb.200301080 |
0.794 |
|
| 2003 |
Ellezam B, Bertrand J, Dergham P, McKerracher L. Vaccination stimulates retinal ganglion cell regeneration in the adult optic nerve. Neurobiology of Disease. 12: 1-10. PMID 12609484 DOI: 10.1016/S0969-9961(02)00013-X |
0.771 |
|
| 2002 |
Ellezam B, Dubreuil C, Winton M, Loy L, Dergham P, Sellés-Navarro I, McKerracher L. Inactivation of intracellular Rho to stimulate axon growth and regeneration. Progress in Brain Research. 137: 371-80. PMID 12440379 DOI: 10.1016/S0079-6123(02)37028-6 |
0.792 |
|
| 2002 |
McKerracher L, Winton MJ. Nogo on the go. Neuron. 36: 345-8. PMID 12408839 DOI: 10.1016/S0896-6273(02)01018-8 |
0.805 |
|
| 2002 |
Dergham P, Ellezam B, Essagian C, Avedissian H, Lubell WD, McKerracher L. Rho signaling pathway targeted to promote spinal cord repair. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6570-7. PMID 12151536 DOI: 10.1523/Jneurosci.22-15-06570.2002 |
0.815 |
|
| 2002 |
Winton MJ, Dubreuil CI, Lasko D, Leclerc N, McKerracher L. Characterization of new cell permeable C3-like proteins that inactivate Rho and stimulate neurite outgrowth on inhibitory substrates. The Journal of Biological Chemistry. 277: 32820-9. PMID 12091381 DOI: 10.1074/Jbc.M201195200 |
0.764 |
|
| 2002 |
McKerracher L. Ganglioside rafts as MAG receptors that mediate blockade of axon growth. Proceedings of the National Academy of Sciences of the United States of America. 99: 7811-3. PMID 12060723 DOI: 10.1073/Pnas.132280299 |
0.593 |
|
| 2002 |
McKerracher L, Ellezam B. Development. Putting the brakes on regeneration. Science (New York, N.Y.). 296: 1819-20. PMID 12052945 DOI: 10.1126/Science.1073590 |
0.618 |
|
| 2001 |
Ellezam B, Selles-Navarro I, Manitt C, Kennedy TE, McKerracher L. Expression of netrin-1 and its receptors DCC and UNC-5H2 after axotomy and during regeneration of adult rat retinal ganglion cells. Experimental Neurology. 168: 105-15. PMID 11170725 DOI: 10.1006/Exnr.2000.7589 |
0.494 |
|
| 2001 |
McKerracher L. Spinal cord repair: Strategies to promote axon regeneration Neurobiology of Disease. 8: 11-18. PMID 11162236 DOI: 10.1006/Nbdi.2000.0359 |
0.645 |
|
| 2001 |
Sellés-Navarro I, Ellezam B, Fajardo R, Latour M, McKerracher L. Retinal ganglion cell and nonneuronal cell responses to a microcrush lesion of adult rat optic nerve Experimental Neurology. 167: 282-289. PMID 11161616 DOI: 10.1006/Exnr.2000.7573 |
0.519 |
|
| 1999 |
Renaudin A, Lehmann M, Girault JA, McKerracher L. Organization of point contacts in neuronal growth cones Journal of Neuroscience Research. 55: 458-471. PMID 10723056 DOI: 10.1002/(Sici)1097-4547(19990215)55:4<458::Aid-Jnr6>3.0.Co;2-D |
0.352 |
|
| 1999 |
Huang DW, McKerracher L, Braun PE, David S. A therapeutic vaccine approach to stimulate axon regeneration in the adult mammalian spinal cord Neuron. 24: 639-647. PMID 10595515 DOI: 10.1016/S0896-6273(00)81118-6 |
0.75 |
|
| 1999 |
Lehmann M, Fournier A, Selles-Navarro I, Dergham P, Sebok A, Leclerc N, Tigyi G, McKerracher L. Inactivation of rho signaling pathway promotes CNS axon regeneration Journal of Neuroscience. 19: 7537-7547. PMID 10460260 DOI: 10.1523/Jneurosci.19-17-07537.1999 |
0.818 |
|
| 1999 |
McKerracher L. Rho family antagonists and their use to block inhibition of neurite growth Expert Opinion On Therapeutic Patents. 9: 1571-1574. DOI: 10.1517/13543776.9.11.1571 |
0.473 |
|
| 1998 |
Song H, Ming G, He Z, Lehmann M, McKerracher L, Tessier-Lavigne M, Poo M. Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides. Science (New York, N.Y.). 281: 1515-8. PMID 9727979 DOI: 10.1126/Science.281.5382.1515 |
0.499 |
|
| 1998 |
Shibata A, Wright MV, David S, McKerracher L, Braun PE, Kater SB. Unique responses of differentiating neuronal growth cones to inhibitory cues presented by oligodendrocytes. The Journal of Cell Biology. 142: 191-202. PMID 9660873 DOI: 10.1083/Jcb.142.1.191 |
0.706 |
|
| 1997 |
Fournier AE, McKerracher L. Expression of specific tubulin isotypes increases during regeneration of injured CNS neurons, but not after the application of brain-derived neurotrophic factor (BDNF) Journal of Neuroscience. 17: 4623-4632. PMID 9169523 DOI: 10.1523/Jneurosci.17-12-04623.1997 |
0.651 |
|
| 1997 |
Fournier AE, Beer J, Arregui CO, Essagian C, Aguayo AJ, McKerracher L. Brain-derived neurotrophic factor modulates GAP-43 but not T alpha1 expression in injured retinal ganglion cells of adult rats. Journal of Neuroscience Research. 47: 561-72. PMID 9089204 DOI: 10.1002/(Sici)1097-4547(19970315)47:6<561::Aid-Jnr1>3.0.Co;2-B |
0.63 |
|
| 1997 |
Fessler R, Quencer R, Hall E, Tessier-Lavigne M, McKerracher L, Kocsis J, Reier P, Snyder E, Bregman B, Edgerton R, Calancie B, Trull FL, Cardenas D, DeLisa J, Whiteneck G, et al. Abstracts from the Spinal Cord Research Foundation’s 20th Anniversary Symposium The Journal of Spinal Cord Medicine. 20: 90-100. DOI: 10.1080/10790268.1997.11719462 |
0.339 |
|
| 1996 |
Li M, Shibata A, Li C, Braun PE, McKerracher L, Roder J, Kater SB, David S. Myelin-associated glycoprotein inhibits neurite/axon growth and causes growth cone collapse. Journal of Neuroscience Research. 46: 404-14. PMID 8950700 DOI: 10.1002/(Sici)1097-4547(19961115)46:4<404::Aid-Jnr2>3.0.Co;2-K |
0.738 |
|
| 1996 |
McKerracher L, Chamoux M, Arregui CO. Role of laminin and integrin interactions in growth cone guidance Molecular Neurobiology. 12: 95-116. PMID 8818145 DOI: 10.1007/Bf02740648 |
0.486 |
|
| 1995 |
Fournier AE, McKerracher L. Tubulin expression and axonal transport in injured and regenerating neurons in the adult mammalian central nervous system Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 659-664. PMID 8714686 DOI: 10.1139/O95-073 |
0.682 |
|
| 1995 |
Minzenberg M, Berkelaar M, Bray G, McKerracher L. Changes in retinal ganglion cell axons after optic nerve crush: neurofilament expression is not the sole determinant of calibre Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 599-604. PMID 8714678 DOI: 10.1139/O95-065 |
0.584 |
|
| 1995 |
David S, Braun PE, Jackson DL, Kottis V, McKerracher L. Laminin overrides the inhibitory effects of peripheral nervous system and central nervous system myelin-derived inhibitors of neurite growth. Journal of Neuroscience Research. 42: 594-602. PMID 8568945 DOI: 10.1002/Jnr.490420417 |
0.736 |
|
| 1994 |
McKerracher L, David S, Jackson DL, Kottis V, Dunn RJ, Braun PE. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron. 13: 805-11. PMID 7524558 DOI: 10.1016/0896-6273(94)90247-X |
0.718 |
|
| 1993 |
McKerracher L, Essagian C, Aguayo AJ. Temporal changes in beta-tubulin and neurofilament mRNA levels after transection of adult rat retinal ganglion cell axons in the optic nerve. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2617-26. PMID 8501527 DOI: 10.1523/Jneurosci.13-06-02617.1993 |
0.588 |
|
| 1993 |
McKerracher L, Essagian C, Aguayo AJ. Marked increase in beta-tubulin mRNA expression during regeneration of axotomized retinal ganglion cells in adult mammals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 5294-300. PMID 8254375 |
0.593 |
|
| 1992 |
McKerracher L, Hirscheimer A. Slow transport of the cytoskeleton after axonal injury Journal of Neurobiology. 23: 568-578. PMID 1279115 DOI: 10.1002/Neu.480230510 |
0.529 |
|
| 1991 |
Aguayo AJ, Rasminsky M, Bray GM, Carbonetto S, McKerracher L, Villegas-Pérez MP, Vidal-Sanz M, Carter DA. Degenerative and regenerative responses of injured neurons in the central nervous system of adult mammals. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 331: 337-43. PMID 1677478 DOI: 10.1098/rstb.1991.0025 |
0.628 |
|
| 1990 |
McKerracher L, Vidal-Sanz M, Aguayo AJ. Slow transport rates of cytoskeletal proteins change during regeneration of axotomized retinal neurons in adult rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 641-8. PMID 2106015 DOI: 10.1523/Jneurosci.10-02-00641.1990 |
0.688 |
|
| 1990 |
McKerracher L, Vidal-Sanz M, Essagian C, Aguayo AJ. Selective impairment of slow axonal transport after optic nerve injury in adult rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2834-41. PMID 1696983 DOI: 10.1523/Jneurosci.10-08-02834.1990 |
0.657 |
|
| 1989 |
McKerracher L, Vallee RB, Aguayo AJ. Microtubule-associated protein 1A (MAP 1A) is a ganglion cell marker in adult rat retina. Visual Neuroscience. 2: 349-56. PMID 2484862 DOI: 10.1017/S0952523800002157 |
0.668 |
|
| 1989 |
Schoenfeld TA, McKerracher L, Obar R, Vallee RB. MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 1712-30. PMID 2470876 DOI: 10.1523/Jneurosci.09-05-01712.1989 |
0.504 |
|
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