Carrie L. Lucas, Ph.D.

Affiliations: 
2010 Harvard University, Cambridge, MA, United States 
Area:
Immunology, Cell Biology
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"Carrie Lucas"

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Megan Sykes grad student 2010 Harvard
 (Mechanisms of Deletional Tolerance of Peripheral CD8+ T Cells Induced by Anti-CD40L and Allogeneic Bone Marrow Transplantation.)
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Publications

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Lanahan SM, Yang L, Jones KM, et al. (2024) PI3Kγ in B cells promotes antibody responses and generation of antibody-secreting cells. Nature Immunology
Axisa PP, Yoshida TM, Lucca LE, et al. (2022) A multiple sclerosis-protective coding variant reveals an essential role for HDAC7 in regulatory T cells. Science Translational Medicine. 14: eabl3651
Reed JC, Preston-Hurlburt P, Philbrick W, et al. (2020) The receptor for advanced glycation endproducts (RAGE) modulates T cell signaling. Plos One. 15: e0236921
Takeda AJ, Maher TJ, Zhang Y, et al. (2019) Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology. Nature Communications. 10: 4364
Carpier JM, Lucas CL. (2017) Epstein-Barr Virus Susceptibility in Activated PI3Kδ Syndrome (APDS) Immunodeficiency. Frontiers in Immunology. 8: 2005
Rao VK, Webster S, Dalm VASH, et al. (2017) Effective 'Activated PI3Kδ Syndrome'-targeted therapy with the PI3Kδ inhibitor leniolisib. Blood
Lucas CL, Chandra A, Nejentsev S, et al. (2016) PI3Kδ and primary immunodeficiencies. Nature Reviews. Immunology
Elkaim E, Neven B, Bruneau J, et al. (2016) Clinical and immunologic phenotype associated with activated phosphoinositide 3-kinase δ syndrome 2: A cohort study. The Journal of Allergy and Clinical Immunology
Lucas CL, Zhang Y, Venida A, et al. (2014) Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K. The Journal of Experimental Medicine. 211: 2537-47
Haspot F, Li HW, Lucas CL, et al. (2014) Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 49-58
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