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Shixin Liu, Ph.D. - Publications

Affiliations: 
2009 Harvard University, Cambridge, MA, United States 
Area:
single-molecule approaches to examine protein-RNA complexes
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ju X, Li S, Froom R, Wang L, Lilic M, Campbell EA, Rock JM, Liu S. Incomplete transcripts dominate the transcriptome. Biorxiv : the Preprint Server For Biology. PMID 36945399 DOI: 10.1101/2023.03.10.532058  0.33
2023 Wang L, Watters JW, Ju X, Lu G, Liu S. Head-on and co-directional RNA polymerase collisions orchestrate bidirectional transcription termination. Molecular Cell. PMID 36917983 DOI: 10.1016/j.molcel.2023.02.017  0.354
2022 Cao X, Liu K, Yan S, Li S, Li Y, Jin T, Liu S. Mechanical regulation of the helicase activity of Zika virus NS3. Biophysical Journal. PMID 35923103 DOI: 10.1016/j.bpj.2022.07.030  0.349
2020 Mickolajczyk KJ, Shelton PMM, Grasso M, Cao X, Warrington SE, Aher A, Liu S, Kapoor TM. Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase. Biophysical Journal. PMID 33340543 DOI: 10.1016/j.bpj.2020.11.2276  0.36
2020 Mickolajczyk KJ, Shelton PMM, Grasso M, Cao X, Warrington SR, Aher A, Liu S, Kapoor TM. Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase. Biorxiv : the Preprint Server For Biology. PMID 32766580 DOI: 10.1101/2020.07.31.231274  0.344
2020 Wang L, Johnson ZL, Wasserman MR, Levring J, Chen J, Liu S. Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses. Elife. 9. PMID 32458799 DOI: 10.7554/Elife.56451  0.358
2020 Leicher R, Ge E, Lin X, Reynolds MJ, Walz T, Zhang B, Muir T, Liu S. Single-Molecule Investigation of PRC2 Non-Adjacent Nucleosome Bridging Biophysical Journal. 118: 380a. DOI: 10.1016/J.Bpj.2019.11.2170  0.307
2019 Li S, Zheng EB, Zhao L, Liu S. Nonreciprocal and Conditional Cooperativity Directs the Pioneer Activity of Pluripotency Transcription Factors. Cell Reports. 28: 2689-2703.e4. PMID 31484078 DOI: 10.1016/J.Celrep.2019.07.103  0.328
2019 Wasserman MR, Schauer GD, O'Donnell ME, Liu S. Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase. Cell. 178: 600-611.e16. PMID 31348887 DOI: 10.1016/J.Bpj.2019.11.2143  0.337
2019 Ju X, Li D, Liu S. Full-length RNA profiling reveals pervasive bidirectional transcription terminators in bacteria. Nature Microbiology. PMID 31308523 DOI: 10.1038/S41564-019-0500-Z  0.43
2019 Wasserman MR, Liu S. A Tour de Force on the Double Helix: Exploiting DNA Mechanics To Study DNA-Based Molecular Machines. Biochemistry. PMID 31251042 DOI: 10.1021/Acs.Biochem.9B00346  0.321
2019 Wang L, Mo CY, Wasserman MR, Rostøl JT, Marraffini LA, Liu S. Dynamics of Cas10 Govern Discrimination between Self and Non-self in Type III CRISPR-Cas Immunity. Molecular Cell. 73: 278-290.e4. PMID 30503774 DOI: 10.1016/J.Molcel.2018.11.008  0.392
2019 Wasserman MR, Schauer GD, O'Donnell ME, Liu S. Replisome Preservation by a Single-Stranded DNA Gate in the CMG Helicase Biophysical Journal. 116: 76a. DOI: 10.1016/J.Bpj.2018.11.450  0.3
2018 Tafoya S, Liu S, Castillo JP, Atz R, Morais MC, Grimes S, Jardine PJ, Bustamante C. Molecular switch-like regulation enables global subunit coordination in a viral ring ATPase. Proceedings of the National Academy of Sciences of the United States of America. PMID 30012596 DOI: 10.1073/Pnas.1802736115  0.351
2017 Liu S, Tafoya S, Bustamante C. Deciphering the Molecular Mechanism of the Bacteriophage φ29 DNA Packaging Motor. Methods in Molecular Biology (Clifton, N.J.). 1486: 343-355. PMID 27844435 DOI: 10.1007/978-1-4939-6421-5_13  0.321
2015 Cheng B, Wu S, Liu S, Rodriguez-Aliaga P, Yu J, Cui S. Protein denaturation at a single-molecule level: the effect of nonpolar environments and its implications on the unfolding mechanism by proteases. Nanoscale. 7: 2970-7. PMID 25597693 DOI: 10.1039/C4Nr07140A  0.327
2014 Liu S, Chistol G, Bustamante C. Mechanical operation and intersubunit coordination of ring-shaped molecular motors: insights from single-molecule studies. Biophysical Journal. 106: 1844-58. PMID 24806916 DOI: 10.1016/J.Bpj.2014.03.029  0.361
2014 Tafoya S, Chistol G, Liu S, Jardine P, Grimes S, Bustamante C. Structural Basis for the Mechano-Chemical Coupling and Inter-Subunit Coordination of Ring ATPase Biophysical Journal. 106: 495a. DOI: 10.1016/J.Bpj.2013.11.2769  0.347
2013 Dangkulwanich M, Ishibashi T, Liu S, Kireeva ML, Lubkowska L, Kashlev M, Bustamante CJ. Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism. Elife. 2: e00971. PMID 24066225 DOI: 10.7554/Elife.00971  0.494
2013 Dangkulwanich M, Ishibashi T, Liu S, Kireeva ML, Lubkowska L, Kashlev M, Bustamante CJ. Author response: Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism Elife. DOI: 10.7554/Elife.00971.024  0.429
2013 Liu S, Chistol G, Tafoya S, Grimes S, Jardine PJ, Bustamante C. Feeling the Pressure: Dynamics of Viral DNA Packaging are Controlled by the Confined Genome within the Capsid Biophysical Journal. 104: 382a. DOI: 10.1016/J.Bpj.2012.11.2126  0.329
2013 Dangkulwanich M, Ishibashi T, Liu S, Kireeva ML, Lubkowska L, Kashlev M, Bustamante C. A Quantitative Kinetic Model of Eukaryotic Transcription Elongation from Single-Molecule Experiments Biophysical Journal. 104: 364a. DOI: 10.1016/J.Bpj.2012.11.2023  0.414
2012 Chistol G, Liu S, Hetherington CL, Moffitt JR, Grimes S, Jardine PJ, Bustamante C. High degree of coordination and division of labor among subunits in a homomeric ring ATPase. Cell. 151: 1017-28. PMID 23178121 DOI: 10.1016/J.Cell.2012.10.031  0.336
2012 Liu S, Chistol G, Hetherington CL, Moffitt JR, Grimes S, Jardine PJ, Bustamante C. Complete Characterization of the Mechanochemical Cycle of a Homomeric Ring ATPase Biophysical Journal. 102: 175a. DOI: 10.1016/J.Bpj.2011.11.948  0.344
2010 Liu S, Harada BT, Miller JT, Le Grice SF, Zhuang X. Initiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription. Nature Structural & Molecular Biology. 17: 1453-60. PMID 21102446 DOI: 10.1038/Nsmb.1937  0.532
2010 Chung S, Wendeler M, Rausch JW, Beilhartz G, Gotte M, O'Keefe BR, Bermingham A, Beutler JA, Liu S, Zhuang X, Le Grice SF. Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H. Antimicrobial Agents and Chemotherapy. 54: 3913-21. PMID 20547794 DOI: 10.1128/Aac.00434-10  0.486
2010 Harada BT, Liu S, Grice SFJL, Zhuang X. Dynamics of the HIV Reverse Transcription Initiation Complex Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.073  0.58
2008 Liu S, Abbondanzieri EA, Rausch JW, Le Grice SF, Zhuang X. Slide into action: dynamic shuttling of HIV reverse transcriptase on nucleic acid substrates. Science (New York, N.Y.). 322: 1092-7. PMID 19008444 DOI: 10.1126/Science.1163108  0.565
2007 Liu S, Bokinsky G, Walter NG, Zhuang X. Dissecting the multistep reaction pathway of an RNA enzyme by single-molecule kinetic "fingerprinting". Proceedings of the National Academy of Sciences of the United States of America. 104: 12634-9. PMID 17496145 DOI: 10.1073/Pnas.0610597104  0.654
2006 Bokinsky G, Nivón LG, Liu S, Chai G, Hong M, Weeks KM, Zhuang X. Two distinct binding modes of a protein cofactor with its target RNA. Journal of Molecular Biology. 361: 771-84. PMID 16872630 DOI: 10.1016/J.Jmb.2006.06.048  0.561
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