Nan M. Laird - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Biostatistics Biology

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hecker J, William Townes F, Kachroo P, Laurie C, Lasky-Su J, Ziniti J, Cho MH, Weiss ST, Laird NM, Lange C. A unifying framework for rare variant association testing in family-based designs, including higher criticism approaches, SKATs, and burden tests. Bioinformatics (Oxford, England). PMID 33367522 DOI: 10.1093/bioinformatics/btaa1055  0.304
2020 Prokopenko D, Hecker J, Kirchner R, Chapman BA, Hoffman O, Mullin K, Hide W, Bertram L, Laird N, DeMeo DL, Lange C, Tanzi RE. Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data. Scientific Reports. 10: 5029. PMID 32193444 DOI: 10.1038/S41598-020-61883-6  0.35
2019 Hecker J, Laird N, Lange C. A comparison of popular TDT-generalizations for family-based association analysis. Genetic Epidemiology. PMID 30609057 DOI: 10.1002/Gepi.22181  0.414
2019 Fitzmaurice GM, Laird NM. Generalized linear mixture models for handling nonignorable dropouts in longitudinal studies. Biostatistics (Oxford, England). 1: 141-56. PMID 12933516 DOI: 10.1093/Biostatistics/1.2.141  0.364
2017 Hecker J, Xu X, Townes FW, Loehlein Fier H, Corcoran C, Laird N, Lange C. Family-based tests for associating haplotypes with general phenotype data: Improving the FBAT-haplotype algorithm. Genetic Epidemiology. PMID 29159827 DOI: 10.1002/Gepi.22094  0.36
2017 Qiao D, Lange C, Laird NM, Won S, Hersh CP, Morrow J, Hobbs BD, Lutz SM, Ruczinski I, Beaty TH, Silverman EK, Cho MH. Gene-based segregation method for identifying rare variants in family-based sequencing studies. Genetic Epidemiology. PMID 28191685 DOI: 10.1002/Gepi.22037  0.408
2015 Lutz SM, Cho MH, Young K, Hersh CP, Castaldi PJ, McDonald ML, Regan E, Mattheisen M, DeMeo DL, Parker M, Foreman M, Make BJ, Jensen RL, Casaburi R, Lomas DA, ... ... Laird NM, et al. A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. Bmc Genetics. 16: 138. PMID 26634245 DOI: 10.1186/S12863-015-0299-4  0.301
2015 DerSimonian R, Laird N. Meta-analysis in clinical trials revisited. Contemporary Clinical Trials. 45: 139-45. PMID 26343745 DOI: 10.1016/J.Cct.2015.09.002  0.356
2015 Zhou JJ, Cho MH, Lange C, Lutz S, Silverman EK, Laird NM. Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability. Human Heredity. 79: 93-104. PMID 26111731 DOI: 10.1159/000381641  0.391
2014 Zhou JJ, Yip WK, Cho MH, Qiao D, McDonald ML, Laird NM. A comparative analysis of family-based and population-based association tests using whole genome sequence data. Bmc Proceedings. 8: S33. PMID 25519381 DOI: 10.1186/1753-6561-8-S1-S33  0.4
2014 Yip WK, Fier H, DeMeo DL, Aryee M, Laird N, Lange C. A novel method for detecting association between DNA methylation and diseases using spatial information. Genetic Epidemiology. 38: 714-21. PMID 25250875 DOI: 10.1002/Gepi.21851  0.311
2014 Cho MH, McDonald ML, Zhou X, Mattheisen M, Castaldi PJ, Hersh CP, Demeo DL, Sylvia JS, Ziniti J, Laird NM, Lange C, Litonjua AA, Sparrow D, Casaburi R, Barr RG, et al. Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. The Lancet. Respiratory Medicine. 2: 214-25. PMID 24621683 DOI: 10.1016/S2213-2600(14)70002-5  0.338
2013 Zhou JJ, Cho MH, Castaldi PJ, Hersh CP, Silverman EK, Laird NM. Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers. American Journal of Respiratory and Critical Care Medicine. 188: 941-7. PMID 23972146 DOI: 10.1164/Rccm.201302-0263Oc  0.309
2013 Lutz S, Yip WK, Hokanson J, Laird N, Lange C. A general semi-parametric approach to the analysis of genetic association studies in population-based designs. Bmc Genetics. 14: 13. PMID 23448186 DOI: 10.1186/1471-2156-14-13  0.374
2013 De G, Yip WK, Ionita-Laza I, Laird N. Rare variant analysis for family-based design. Plos One. 8: e48495. PMID 23341868 DOI: 10.1371/Journal.Pone.0048495  0.762
2013 Ionita-Laza I, Cho MH, Laird NM. Statistical Challenges in Sequence-Based Association Studies with Population- and Family-Based Designs Statistics in Biosciences. 5: 54-70. DOI: 10.1007/S12561-012-9062-9  0.359
2012 Adhikari K, AlChawa T, Ludwig K, Mangold E, Laird N, Lange C. Is it rare or common? Genetic Epidemiology. 36: 419-29. PMID 22549767 DOI: 10.1002/Gepi.21637  0.363
2012 Sebro R, Lange C, Laird NM, Rogus JJ, Risch NJ. Differentiating population stratification from genotyping error using family data. Annals of Human Genetics. 76: 42-52. PMID 22111716 DOI: 10.1111/J.1469-1809.2011.00689.X  0.61
2011 Yan A, Laird NM, Li C. Identifying rare variants using a Bayesian regression approach. Bmc Proceedings. 5: S99. PMID 22373362 DOI: 10.1186/1753-6561-5-S9-S99  0.369
2011 Ghosh S, Bickeböller H, Bailey J, Bailey-Wilson JE, Cantor R, Culverhouse R, Daw W, Destefano AL, Engelman CD, Hinrichs A, Houwing-Duistermaat J, König IR, Kent J, Laird N, Pankratz N, et al. Identifying rare variants from exome scans: the GAW17 experience. Bmc Proceedings. 5: S1. PMID 22373325 DOI: 10.1186/1753-6561-5-S9-S1  0.334
2011 Yip WK, De G, Raby BA, Laird N. Identifying causal rare variants of disease through family-based analysis of Genetics Analysis Workshop 17 data set. Bmc Proceedings. 5: S21. PMID 22373204 DOI: 10.1186/1753-6561-5-S9-S21  0.763
2011 Castaldi PJ, Cho MH, Litonjua AA, Bakke P, Gulsvik A, Lomas DA, Anderson W, Beaty TH, Hokanson JE, Crapo JD, Laird N, Silverman EK. The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility American Journal of Respiratory Cell and Molecular Biology. 45: 1147-1153. PMID 21659657 DOI: 10.1165/Rcmb.2011-0055Oc  0.35
2011 Yoon FB, Fitzmaurice GM, Lipsitz SR, Horton NJ, Laird NM, Normand SL. Alternative methods for testing treatment effects on the basis of multiple outcomes: simulation and case study. Statistics in Medicine. 30: 1917-32. PMID 21538986 DOI: 10.1002/Sim.4262  0.316
2011 Howrigan DP, Laird NM, Smoller JW, Devlin B, McQueen MB. Using linkage information to weight a genome-wide association of bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 462-71. PMID 21480485 DOI: 10.1002/Ajmg.B.31183  0.368
2011 Javaras KN, Goldsmith HH, Laird NM. Estimating the effect of a predictor measured by two informants on a continuous outcome: a comparison of methods. Epidemiology (Cambridge, Mass.). 22: 390-9. PMID 21403520 DOI: 10.1097/Ede.0B013E318212B940  0.323
2011 Hoffmann TJ, Vansteelandt S, Lange C, Silverman EK, DeMeo DL, Laird NM. Combining disease models to test for gene-environment interaction in nuclear families. Biometrics. 67: 1260-70. PMID 21401569 DOI: 10.1111/J.1541-0420.2011.01581.X  0.566
2011 Ionita-Laza I, Buxbaum JD, Laird NM, Lange C. A new testing strategy to identify rare variants with either risk or protective effect on disease. Plos Genetics. 7: e1001289. PMID 21304886 DOI: 10.1371/Journal.Pgen.1001289  0.372
2011 VanderWeele TJ, Laird NM. Tests for compositional epistasis under single interaction-parameter models. Annals of Human Genetics. 75: 146-56. PMID 20726965 DOI: 10.1111/J.1469-1809.2010.00600.X  0.347
2011 Litman HJ, Horton NJ, Hernández B, Laird NM. Estimation of Marginal Regression Models with Multiple Source Predictors Essential Statistical Methods For Medical Statistics. 27: 291-307. DOI: 10.1016/B978-0-444-53737-9.50013-X  0.561
2010 Sinha SK, Laird NM, Fitzmaurice GM. Multivariate logistic regression with incomplete covariate and auxiliary information. Journal of Multivariate Analysis. 101: 2389-2397. PMID 20953361 DOI: 10.1016/J.Jmva.2010.06.010  0.354
2010 Ionita-Laza I, Laird NM. On the optimal design of genetic variant discovery studies. Statistical Applications in Genetics and Molecular Biology. 9: Article33. PMID 20812911 DOI: 10.2202/1544-6115.1581  0.34
2010 Moreno-Macias H, Romieu I, London SJ, Laird NM. Gene-environment interaction tests for family studies with quantitative phenotypes: A review and extension to longitudinal measures. Human Genomics. 4: 302-26. PMID 20650819 DOI: 10.1186/1479-7364-4-5-302  0.376
2010 Laird N, Fitzmaurice G, Ding X. Comments on 'Empirical vs natural weighting in random effects meta-analysis'. Statistics in Medicine. 29: 1266-7; discussion 1. PMID 20499329 DOI: 10.1002/Sim.3657  0.456
2010 Cho MH, Washko GR, Hoffmann TJ, Criner GJ, Hoffman EA, Martinez FJ, Laird N, Reilly JJ, Silverman EK. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation. Respiratory Research. 11: 30. PMID 20233420 DOI: 10.1186/1465-9921-11-30  0.513
2010 Hoffmann TJ, Lange C, Vansteelandt S, Raby BA, DeMeo DL, Silverman EK, Weiss ST, Laird NM. Parsing the effects of individual SNPs in candidate genes with family data. Human Heredity. 69: 91-103. PMID 19996607 DOI: 10.1159/000264447  0.592
2010 Javaras KN, Hudson JI, Laird NM. Fitting ACE structural equation models to case-control family data. Genetic Epidemiology. 34: 238-45. PMID 19918760 DOI: 10.1002/Gepi.20454  0.383
2010 Javaras KN, Laird NM, Hudson JI, Ripley BD. Estimating disease prevalence using relatives of case and control probands. Biometrics. 66: 214-21. PMID 19459833 DOI: 10.1111/J.1541-0420.2009.01272.X  0.36
2010 Fan J, Ionita-Laza I, McQueen MB, Devlin B, Purcell S, Faraone SV, Allen MH, Bowden CL, Calabrese JR, Fossey MD, Friedman ES, Gyulai L, Hauser P, Ketter TB, Marangell LB, ... ... Laird NM, et al. Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 29-37. PMID 19308960 DOI: 10.1002/Ajmg.B.30942  0.353
2009 Hoffmann TJ, Laird NM. fgui: A Method for Automatically Creating Graphical User Interfaces for Command-Line R Packages. Journal of Statistical Software. 30. PMID 21625291 DOI: 10.18637/Jss.V030.I02  0.434
2009 Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, ... ... Laird N, et al. Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? Plos Genetics. 5: e1000694. PMID 19851442 DOI: 10.1371/Journal.Pgen.1000694  0.306
2009 Mansour HA, Talkowski ME, Wood J, Chowdari KV, McClain L, Prasad K, Montrose D, Fagiolini A, Friedman ES, Allen MH, Bowden CL, Calabrese J, El-Mallakh RS, Escamilla M, Faraone SV, ... ... Laird N, et al. Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia. Bipolar Disorders. 11: 701-10. PMID 19839995 DOI: 10.1111/J.1399-5618.2009.00756.X  0.333
2009 Hoffmann TJ, Lange C, Vansteelandt S, Laird NM. Gene-environment interaction tests for dichotomous traits in trios and sibships. Genetic Epidemiology. 33: 691-9. PMID 19365860 DOI: 10.1002/Gepi.20421  0.551
2009 Ding X, Laird N. Family-Based Association Tests with longitudinal measurements: handling missing data. Human Heredity. 68: 98-105. PMID 19365136 DOI: 10.1159/000212502  0.567
2009 Ding X, Weiss S, Raby B, Lange C, Laird NM. Impact of population stratification on family-based association tests with longitudinal measurements. Statistical Applications in Genetics and Molecular Biology. 8: Article 17. PMID 19222384 DOI: 10.2202/1544-6115.1398  0.561
2009 Sato Y, Laird NM, Nagashima K, Kato R, Hamano T, Yafune A, Kaniwa N, Saito Y, Sugiyama E, Kim SR, Furuse J, Ishii H, Ueno H, Okusaka T, Saijo N, et al. A new statistical screening approach for finding pharmacokinetics-related genes in genome-wide studies. The Pharmacogenomics Journal. 9: 137-46. PMID 19104505 DOI: 10.1038/Tpj.2008.17  0.382
2009 Ding X, Lange C, Xu X, Laird N. New powerful approaches for family-based association tests with longitudinal measurements. Annals of Human Genetics. 73: 74-83. PMID 18798838 DOI: 10.1111/J.1469-1809.2008.00481.X  0.547
2009 Laird NM, Lange C. The role of family-based designs in genome-wide association studies Statistical Science. 24: 388-397. DOI: 10.1214/08-Sts280  0.352
2008 Neale BM, Lasky-Su J, Anney R, Franke B, Zhou K, Maller JB, Vasquez AA, Asherson P, Chen W, Banaschewski T, Buitelaar J, Ebstein R, Gill M, Miranda A, Oades RD, ... ... Laird N, et al. Genome-wide association scan of attention deficit hyperactivity disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1337-44. PMID 18980221 DOI: 10.1002/Ajmg.B.30866  0.346
2008 Bertram L, Lange C, Mullin K, Parkinson M, Hsiao M, Hogan MF, Schjeide BM, Hooli B, Divito J, Ionita I, Jiang H, Laird N, Moscarillo T, Ohlsen KL, Elliott K, et al. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. American Journal of Human Genetics. 83: 623-32. PMID 18976728 DOI: 10.1016/J.Ajhg.2008.10.008  0.347
2008 Lasky-Su J, Anney RJ, Neale BM, Franke B, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, ... ... Laird N, et al. Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1355-8. PMID 18937294 DOI: 10.1002/Ajmg.B.30869  0.335
2008 Lasky-Su J, Neale BM, Franke B, Anney RJ, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, ... ... Laird N, et al. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1345-54. PMID 18821565 DOI: 10.1002/Ajmg.B.30867  0.335
2008 Lasky-Su J, Lyon HN, Emilsson V, Heid IM, Molony C, Raby BA, Lazarus R, Klanderman B, Soto-Quiros ME, Avila L, Silverman EK, Thorleifsson G, Thorsteinsdottir U, Kronenberg F, Vollmert C, ... ... Laird N, et al. On the replication of genetic associations: timing can be everything! American Journal of Human Genetics. 82: 849-58. PMID 18387595 DOI: 10.1016/J.Ajhg.2008.01.018  0.508
2008 Rakovski CS, Weiss ST, Laird NM, Lange C. FBAT-SNP-PC: an approach for multiple markers and single trait in family-based association tests. Human Heredity. 66: 122-6. PMID 18382091 DOI: 10.1159/000119111  0.716
2008 Hudson JI, Javaras KN, Laird NM, VanderWeele TJ, Pope HG, Hernán MA. A structural approach to the familial coaggregation of disorders. Epidemiology (Cambridge, Mass.). 19: 431-9. PMID 18379420 DOI: 10.1097/Ede.0B013E31816A9De7  0.363
2008 Laird NM, Lange C. Family-based methods for linkage and association analysis. Advances in Genetics. 60: 219-52. PMID 18358323 DOI: 10.1016/S0065-2660(07)00410-5  0.378
2008 Ionita-Laza I, Perry GH, Raby BA, Klanderman B, Lee C, Laird NM, Weiss ST, Lange C. On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test. Genetic Epidemiology. 32: 273-84. PMID 18228561 DOI: 10.1002/Gepi.20302  0.412
2008 Javaras KN, Laird NM, Reichborn-Kjennerud T, Bulik CM, Pope HG, Hudson JI. Familiality and heritability of binge eating disorder: results of a case-control family study and a twin study. The International Journal of Eating Disorders. 41: 174-9. PMID 18095307 DOI: 10.1002/Eat.20484  0.311
2008 Lasky-Su J, Lange C, Biederman J, Tsuang M, Doyle AE, Smoller JW, Laird N, Faraone S. Family-based association analysis of a statistically derived quantitative traits for ADHD reveal an association in DRD4 with inattentive symptoms in ADHD individuals. American Journal of Medical Genetics. 147: 100-106. PMID 17579349 DOI: 10.1002/Ajmg.B.30567  0.302
2008 Ionita-Laza I, McQueen MB, Weiss S, Laird NM, Lange C. Response to Macgregor American Journal of Human Genetics. 82: 799-800. DOI: 10.1016/J.Ajhg.2008.02.002  0.393
2007 Harezlak J, Coull BA, Laird NM, Magari SR, Christiani DC. Penalized solutions to functional regression problems. Computational Statistics & Data Analysis. 51: 4911-4925. PMID 18552972 DOI: 10.1016/J.Csda.2006.09.034  0.574
2007 Schneiter K, Degnan JH, Corcoran C, Xu X, Laird N. EFBAT: exact family-based association tests. Bmc Genetics. 8: 86. PMID 18096066 DOI: 10.1186/1471-2156-8-86  0.388
2007 Ionita-Laza I, McQueen MB, Laird NM, Lange C. Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan. American Journal of Human Genetics. 81: 607-14. PMID 17701906 DOI: 10.1086/519748  0.413
2007 Lasky-Su J, Biederman J, Laird N, Tsuang M, Doyle AE, Smoller JW, Lange C, Faraone SV. Evidence for an association of the dopamine D5 receptor gene on age at onset of attention deficit hyperactivity disorder. Annals of Human Genetics. 71: 648-59. PMID 17501935 DOI: 10.1111/J.1469-1809.2007.00366.X  0.32
2007 Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen TT, Scherag A, Pfeufer A, ... ... Laird N, et al. The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. Plos Genetics. 3: e61. PMID 17465681 DOI: 10.1371/Journal.Pgen.0030061  0.539
2007 McQueen MB, Weiss S, Laird NM, Lange C. On the parsing of statistical information in family-based association testing. Nature Genetics. 39: 281-2. PMID 17325672 DOI: 10.1038/Ng0307-281  0.376
2007 Van Steen K, Laird NM, Markel P, Molenberghs G. Approaches to handling incomplete data in family-based association testing Annals of Human Genetics. 71: 141-151. PMID 17096676 DOI: 10.1111/J.1469-1809.2006.00325.X  0.404
2007 Rakovski CS, Xu X, Lazarus R, Blacker D, Laird NM. A new multimarker test for family-based association studies. Genetic Epidemiology. 31: 9-17. PMID 17086514 DOI: 10.1002/Gepi.20186  0.723
2007 Xu X, Rakovski C, Xu X, Laird N. An efficient family-based association test using multiple markers. Genetic Epidemiology. 30: 620-6. PMID 16868964 DOI: 10.1002/Gepi.20174  0.686
2007 Harezlak J, Naumova E, Laird NM. LongCriSP: a test for bump hunting in longitudinal data. Statistics in Medicine. 26: 1383-97. PMID 16850452 DOI: 10.1002/Sim.2623  0.601
2007 Litman HJ, Horton NJ, Hernández B, Laird NM. Incorporating missingness for estimation of marginal regression models with multiple source predictors. Statistics in Medicine. 26: 1055-68. PMID 16755531 DOI: 10.1002/Sim.2593  0.614
2007 Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann H, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, ... ... Laird NM, et al. Response to Comments on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity" Science. 315: 187e-187e. DOI: 10.1126/Science.1129763  0.323
2007 Litman HJ, Horton NJ, Hernández B, Laird NM. 25 Estimation of Marginal Regression Models with Multiple Source Predictors Handbook of Statistics. 27: 730-746. DOI: 10.1016/S0169-7161(07)27025-7  0.633
2006 Litman HJ, Horton NJ, Murphy JM, Laird NM. Marginal regression models with a time to event outcome and discrete multiple source predictors. Lifetime Data Analysis. 12: 249-65. PMID 17021951 DOI: 10.1007/S10985-006-9013-1  0.629
2006 McQueen MB, Blacker D, Laird NM. Variance calculations for identity-by-descent estimation. American Journal of Human Genetics. 78: 914-21. PMID 16685643 DOI: 10.1086/503920  0.359
2006 Wang L, Wang X, Laird N, Zuckerman B, Stubblefield P, Xu X. Polymorphism in maternal LRP8 gene is associated with fetal growth. American Journal of Human Genetics. 78: 770-777. PMID 16642433 DOI: 10.1086/503712  0.32
2006 Laird NM, Lange C. Family-based designs in the age of large-scale gene-association studies. Nature Reviews. Genetics. 7: 385-94. PMID 16619052 DOI: 10.1038/Nrg1839  0.381
2006 Hsu YH, Niu T, Terwedow HA, Xu X, Feng Y, Li Z, Brain JD, Rosen CJ, Laird N, Xu X. Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men. Human Genetics. 118: 568-77. PMID 16249885 DOI: 10.1007/S00439-005-0062-4  0.309
2005 McQueen MB, Murphy A, Kraft P, Su J, Lazarus R, Laird NM, Lange C, Van Steen K. Comparison of linkage and association strategies for quantitative traits using the COGA dataset. Bmc Genetics. 6: S96. PMID 16451712 DOI: 10.1186/1471-2156-6-S1-S96  0.372
2005 Murphy A, McQueen MB, Su J, Kraft P, Lazarus R, Laird NM, Lange C, Van Steen K. Genomic screening in family-based association testing. Bmc Genetics. 6: S115. PMID 16451572 DOI: 10.1186/1471-2156-6-S1-S115  0.394
2005 McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, ... ... Laird NM, et al. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. American Journal of Human Genetics. 77: 582-95. PMID 16175504 DOI: 10.1086/491603  0.345
2005 Schneiter K, Laird N, Corcoran C. Exact family-based association tests for biallelic data. Genetic Epidemiology. 29: 185-94. PMID 16094642 DOI: 10.1002/Gepi.20088  0.429
2005 Smoller JW, Yamaki LH, Fagerness JA, Biederman J, Racette S, Laird NM, Kagan J, Snidman N, Faraone SV, Hirshfeld-Becker D, Tsuang MT, Slaugenhaupt SA, Rosenbaum JF, Sklar PB. The corticotropin-releasing hormone gene and behavioral inhibition in children at risk for panic disorder. Biological Psychiatry. 57: 1485-92. PMID 15953484 DOI: 10.1016/J.Biopsych.2005.02.018  0.348
2005 Van Steen K, McQueen MB, Herbert A, Raby B, Lyon H, Demeo DL, Murphy A, Su J, Datta S, Rosenow C, Christman M, Silverman EK, Laird NM, Weiss ST, Lange C. Genomic screening and replication using the same data set in family-based association testing. Nature Genetics. 37: 683-91. PMID 15937480 DOI: 10.1038/Ng1582  0.371
2005 Hersh CP, Demeo DL, Lange C, Litonjua AA, Reilly JJ, Kwiatkowski D, Laird N, Sylvia JS, Sparrow D, Speizer FE, Weiss ST, Silverman EK. Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. American Journal of Respiratory Cell and Molecular Biology. 33: 71-8. PMID 15817713 DOI: 10.1165/Rcmb.2005-0073Oc  0.348
2004 Lange C, van Steen K, Andrew T, Lyon H, DeMeo DL, Raby B, Murphy A, Silverman EK, MacGregor A, Weiss ST, Laird NM. A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects. Statistical Applications in Genetics and Molecular Biology. 3: Article17. PMID 16646795 DOI: 10.2202/1544-6115.1067  0.357
2004 Abecasis G, Cox N, Daly MJ, Kruglyak L, Laird N, Markianos K, Patterson N. No bias in linkage analysis. American Journal of Human Genetics. 75: 722-3; author reply . PMID 15338460 DOI: 10.1086/424757  0.407
2004 Celedón JC, Lange C, Raby BA, Litonjua AA, Palmer LJ, DeMeo DL, Reilly JJ, Kwiatkowski DJ, Chapman HA, Laird N, Sylvia JS, Hernandez M, Speizer FE, Weiss ST, Silverman EK. The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Human Molecular Genetics. 13: 1649-56. PMID 15175276 DOI: 10.1093/Hmg/Ddh171  0.301
2004 Feng Y, Niu T, Xing H, Xu X, Chen C, Peng S, Wang L, Laird N, Xu X. A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men. American Journal of Human Genetics. 75: 112-21. PMID 15154117 DOI: 10.1086/422194  0.301
2004 Hao K, Wang X, Niu T, Xu X, Li A, Chang W, Wang L, Li G, Laird N, Xu X. A candidate gene association study on preterm delivery: application of high-throughput genotyping technology and advanced statistical methods. Human Molecular Genetics. 13: 683-91. PMID 14976157 DOI: 10.1093/Hmg/Ddh091  0.367
2004 Lake SL, Laird NM. Tests of gene-environment interaction for case-parent triads with general environmental exposures. Annals of Human Genetics. 68: 55-64. PMID 14748830 DOI: 10.1046/J.1529-8817.2003.00073.X  0.31
2004 Lange C, DeMeo D, Silverman EK, Weiss ST, Laird NM. PBAT: tools for family-based association studies. American Journal of Human Genetics. 74: 367-9. PMID 14740322 DOI: 10.1086/381563  0.392
2004 Lange C, Blacker D, Laird NM. Family-based association tests for survival and times-to-onset analysis. Statistics in Medicine. 23: 179-89. PMID 14716720 DOI: 10.1002/Sim.1707  0.413
2004 Horvath S, Xu X, Lake SL, Silverman EK, Weiss ST, Laird NM. Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genetic Epidemiology. 26: 61-9. PMID 14691957 DOI: 10.1002/Gepi.10295  0.408
2004 Hao K, Xu X, Laird N, Wang X, Xu X. Power estimation of multiple SNP association test of case-control study and application. Genetic Epidemiology. 26: 22-30. PMID 14691954 DOI: 10.1002/Gepi.10293  0.395
2003 Smoller JW, Rosenbaum JF, Biederman J, Kennedy J, Dai D, Racette SR, Laird NM, Kagan J, Snidman N, Hirshfeld-Becker D, Tsuang MT, Sklar PB, Slaugenhaupt SA. Association of a genetic marker at the corticotropin-releasing hormone locus with behavioral inhibition. Biological Psychiatry. 54: 1376-81. PMID 14675801 DOI: 10.1016/S0006-3223(03)00598-5  0.327
2003 Lange C, DeMeo D, Silverman EK, Weiss ST, Laird NM. Using the noninformative families in family-based association tests: a powerful new testing strategy. American Journal of Human Genetics. 73: 801-11. PMID 14502464 DOI: 10.1086/378591  0.41
2003 Saunders AJ, Bertram L, Mullin K, Sampson AJ, Latifzai K, Basu S, Jones J, Kinney D, MacKenzie-Ingano L, Yu S, Albert MS, Moscarillo TJ, Go RC, Bassett SS, Daly MJ, ... Laird NM, et al. Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin. Human Molecular Genetics. 12: 2765-76. PMID 12966032 DOI: 10.1093/Hmg/Ddg310  0.362
2003 Lange C, Silverman EK, Xu X, Weiss ST, Laird NM. A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics (Oxford, England). 4: 195-206. PMID 12925516 DOI: 10.1093/Biostatistics/4.2.195  0.409
2003 Lake SL, Lyon H, Tantisira K, Silverman EK, Weiss ST, Laird NM, Schaid DJ. Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous. Human Heredity. 55: 56-65. PMID 12890927 DOI: 10.1159/000071811  0.396
2003 Slasor P, Laird N. Joint models for efficient estimation in proportional hazards regression models. Statistics in Medicine. 22: 2137-2148. PMID 12820279 DOI: 10.1002/Sim.1439  0.332
2003 Laird NM, Cuenco KT. Regression methods for assessing familial aggregation of disease. Statistics in Medicine. 22: 1447-55. PMID 12704608 DOI: 10.1002/Sim.1504  0.329
2002 Lange C, DeMeo DL, Laird NM. Power and design considerations for a general class of family-based association tests: quantitative traits. American Journal of Human Genetics. 71: 1330-41. PMID 12454799 DOI: 10.1086/344696  0.385
2002 DeMeo DL, Lange C, Silverman EK, Senter JM, Drazen JM, Barth MJ, Laird N, Weiss ST. Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program. Genetic Epidemiology. 23: 335-48. PMID 12432502 DOI: 10.1002/Gepi.10182  0.32
2002 Lange C, Laird NM. On a general class of conditional tests for family-based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations. Genetic Epidemiology. 23: 165-80. PMID 12214309 DOI: 10.1002/Gepi.209  0.397
2002 Lange C, Laird NM. Power calculations for a general class of family-based association tests: dichotomous traits. American Journal of Human Genetics. 71: 575-84. PMID 12181775 DOI: 10.1086/342406  0.336
2001 Naumova EN, Must A, Laird NM. Tutorial in Biostatistics: Evaluating the impact of 'critical periods' in longitudinal studies of growth using piecewise mixed effects models. International Journal of Epidemiology. 30: 1332-41. PMID 11821342 DOI: 10.1093/Ije/30.6.1332  0.323
2001 Horton NJ, Laird NM, Murphy JM, Monson RR, Sobol AM, Leighton AH. Multiple informants: mortality associated with psychiatric disorders in the Stirling County Study. American Journal of Epidemiology. 154: 649-56. PMID 11581099 DOI: 10.1093/Aje/154.7.649  0.312
2001 Smoller JW, Rosenbaum JF, Biederman J, Susswein LS, Kennedy J, Kagan J, Snidman N, Laird N, Tsuang MT, Faraone SV, Schwarz A, Slaugenhaupt SA. Genetic association analysis of behavioral inhibition using candidate loci from mouse models. American Journal of Medical Genetics. 105: 226-35. PMID 11353440 DOI: 10.1002/Ajmg.1328  0.339
2001 Horvath S, Xu X, Laird NM. The family based association test method: strategies for studying general genotype--phenotype associations. European Journal of Human Genetics : Ejhg. 9: 301-6. PMID 11313775 DOI: 10.1038/Sj.Ejhg.5200625  0.429
2001 Fitzmaurice GM, Laird NM, Shneyer L. An alternative parameterization of the general linear mixture model for longitudinal data with non-ignorable drop-outs Statistics in Medicine. 20: 1009-1021. PMID 11276032 DOI: 10.1002/Sim.718  0.3
2001 Horton NJ, Laird NM. Maximum likelihood analysis of logistic regression models with incomplete covariate data and auxiliary information Biometrics. 57: 34-42. PMID 11252616 DOI: 10.1111/J.0006-341X.2001.00034.X  0.38
2001 Hudson JI, Laird NM, Betensky RA, Keck PE, Pope HG. Multivariate logistic regression for familial aggregation of two disorders. II. Analysis of studies of eating and mood disorders American Journal of Epidemiology. 153: 506-514. PMID 11226983 DOI: 10.1093/Aje/153.5.506  0.317
2001 Hudson JI, Laird NM, Betensky RA. Multivariate logistic regression for familial aggregation of two disorders. I. Development of models and methods American Journal of Epidemiology. 153: 500-505. PMID 11226971 DOI: 10.1093/Aje/153.5.500  0.333
2000 Lake SL, Blacker D, Laird NM. Family-based tests of association in the presence of linkage. American Journal of Human Genetics. 67: 1515-25. PMID 11058432 DOI: 10.1086/316895  0.415
2000 Laird NM, Horvath S, Xu X. Implementing a unified approach to family-based tests of association. Genetic Epidemiology. 19: S36-42. PMID 11055368 DOI: 10.1002/1098-2272(2000)19:1+<::Aid-Gepi6>3.0.Co;2-M  0.41
2000 Pauler DK, Laird NM. A mixture model for longitudinal data with application to assessment of noncompliance Biometrics. 56: 464-472. PMID 10877305 DOI: 10.1111/J.0006-341X.2000.00464.X  0.319
2000 Rabinowitz D, Laird N. A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Human Heredity. 50: 211-23. PMID 10782012 DOI: 10.1159/000022918  0.403
2000 Horvath S, Laird NM, Knapp M. The transmission/disequilibrium test and parental-genotype reconstruction for X-chromosomal markers. American Journal of Human Genetics. 66: 1161-7. PMID 10712229 DOI: 10.1086/302823  0.345
2000 Lunetta KL, Faraone SV, Biederman J, Laird NM. Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions American Journal of Human Genetics. 66: 605-614. PMID 10677320 DOI: 10.1086/302782  0.424
2000 Laird NM, Fitzmaurice GM, Schwartz AG. 15 The analysis of case-control data: Epidemiologic studies of familial aggregation Handbook of Statistics. 18: 465-482. DOI: 10.1016/S0169-7161(00)18017-4  0.303
1999 Korhonen PA, Laird NM, Palmgren J. Correcting for non-compliance in randomized trials: An application to the ATBC Study Statistics in Medicine. 18: 2879-2897. PMID 10523748 DOI: 10.1002/(Sici)1097-0258(19991115)18:21<2879::Aid-Sim190>3.0.Co;2-K  0.322
1999 Horton NJ, Laird NM. Maximum likelihood analysis of generalized linear models with missing covariates Statistical Methods in Medical Research. 8: 37-50. PMID 10347859 DOI: 10.1177/096228029900800104  0.347
1999 Niu T, Yang J, Wang B, Chen W, Wang Z, Laird N, Wei E, Fang Z, Lindpaintner K, Rogus JJ, Xu X. Angiotensinogen gene polymorphisms M235T/T174M: No excess transmission to hypertensive chinese Hypertension. 33: 698-702. PMID 10024331 DOI: 10.1161/01.Hyp.33.2.698  0.321
1999 Horton NJ, Laird NM, Zahner GEP. Use of multiple informant data as a predictor in psychiatric epidemiology International Journal of Methods in Psychiatric Research. 8: 6-18. DOI: 10.1002/Mpr.52  0.319
1998 Laird NM, Blacker D, Wilcox M, Ewens WJ, Spielman RS. The sib transmission/disequilibrium test is a Mantel-Haenszel test [5] (multiple letters) American Journal of Human Genetics. 63: 1915-1916. PMID 9838272 DOI: 10.1086/302151  0.394
1998 Horvath S, Laird NM. A discordant-sibship test for disequilibrium and linkage: no need for parental data. American Journal of Human Genetics. 63: 1886-97. PMID 9837840 DOI: 10.1086/302137  0.394
1998 Lipsitz SR, Dear KBG, Laird NM, Molenberghs G. Tests for homogeneity of the risk difference when data are sparse Biometrics. 54: 148-160. PMID 9544513 DOI: 10.2307/2534003  0.347
1998 Hogan JW, Laird NM. Increasing efficiency from censored survival data by using random effects to model longitudinal covariates Statistical Methods in Medical Research. 7: 28-48. PMID 9533260 DOI: 10.1177/096228029800700104  0.306
1997 Cnaan A, Laird NM, Slasor P. Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data Statistics in Medicine. 16: 2349-2380. PMID 9351170 DOI: 10.1002/(Sici)1097-0258(19971030)16:20<2349::Aid-Sim667>3.0.Co;2-E  0.34
1997 Fitzmaurice GM, Laird NM. Regression models for mixed discrete and continuous responses with potentially missing values Biometrics. 53: 110-122. PMID 9147588 DOI: 10.2307/2533101  0.369
1997 Hogan JW, Laird NM. Model-based approaches to analysing incomplete longitudinal and failure time data Statistics in Medicine. 16: 259-272. PMID 9004396 DOI: 10.1002/(Sici)1097-0258(19970215)16:3<259::Aid-Sim484>3.0.Co;2-S  0.309
1997 Hogan JW, Laird NM. Mixture models for the joint distribution of repeated measures and event times Statistics in Medicine. 16: 239-257. PMID 9004395 DOI: 10.1002/(Sici)1097-0258(19970215)16:3<239::Aid-Sim483>3.0.Co;2-X  0.312
1997 Shah A, Laird N, Schoenfeld D. A Random-Effects Model for Multiple Characteristics with Possibly Missing Data Journal of the American Statistical Association. 92: 775-779. DOI: 10.1080/01621459.1997.10474030  0.329
1996 Hogan JW, Laird NM. Intention-to-treat analyses for incomplete repeated measures data Biometrics. 52: 1002-1017. PMID 8805765 DOI: 10.2307/2533061  0.347
1996 Fitzmaurice GM, Laird NM, Zahner GEP. Multivariate logistic models for incomplete binary responses Journal of the American Statistical Association. 91: 99-108. DOI: 10.1080/01621459.1996.10476667  0.319
1995 Wang-Clow F, Lange M, Laird NM, Ware JH. A simulation study of estimators for rates of change in longitudinal studies with attrition Statistics in Medicine. 14: 283-297. PMID 7724914 DOI: 10.1016/0197-2456(91)90211-4  0.354
1995 Fitzmaurice GM, Laird NM, Zahner GEP, Daskalakis C. Bivariate logistic regression analysis of childhood psychopathology ratings using multiple informants American Journal of Epidemiology. 142: 1194-1203. PMID 7485066 DOI: 10.1093/Oxfordjournals.Aje.A117578  0.313
1995 Donnelly CA, Laird NM, Ware JH. Prediction and creation of smooth curves for temporally correlated longitudinal data Journal of the American Statistical Association. 90: 984-989. DOI: 10.1080/01621459.1995.10476599  0.338
1995 Fitzmaurice GM, Laird NM. Regression models for a bivariate discrete and continuous outcome with clustering Journal of the American Statistical Association. 90: 845-852. DOI: 10.1080/01621459.1995.10476583  0.358
1994 Lipsitz SR, Fitzmaurice GM, Orav EJ, Laird NM. Performance of generalized estimating equations in practical situations Biometrics. 50: 270-278. PMID 8086610 DOI: 10.2307/2533218  0.321
1994 Lipsitz SR, Laird NM, Harrington DP. Weighted least squares analysis of repeated categorical measurements with outcomes subject to nonresponse Biometrics. 50: 11-24. PMID 8086595 DOI: 10.2307/2533193  0.324
1994 Fitzmaurice GM, Laird NM, Lipsitz SR. Analysing incomplete longitudinal binary responses: A likelihood-based approach Biometrics. 50: 601-612. PMID 7981387 DOI: 10.2307/2532775  0.366
1994 Donnelly CA, Ware JH, Laird NM. 19 Regression analysis of spatially correlated data: The kanawha county health study Handbook of Statistics. 12: 643-660. DOI: 10.1016/S0169-7161(05)80021-5  0.327
1993 Fitzmaurice GM, Laird NM, Rotnitzky AG. Regression models for discrete longitudinal responses Statistical Science. 8: 284-299. DOI: 10.1214/Ss/1177010899  0.354
1993 Fitzmaurice GM, Laird NM. A likelihood-based method for analysing longitudinal binary responses Biometrika. 80: 141-151. DOI: 10.1093/Biomet/80.1.141  0.377
1993 Glynn RJ, Laird NM, Rubin DB. Multiple imputation in mixture models for nonignorable nonresponse with follow-ups Journal of the American Statistical Association. 88: 984-993. DOI: 10.1080/01621459.1993.10476366  0.334
1992 Lipsitz SR, Laird NM, Harrington DP. A Three-Stage Estimator for Studies with Repeated and Possibly Missing Binary Outcomes Applied Statistics. 41: 203. DOI: 10.2307/2347629  0.336
1991 Lipsitz SR, Laird NM, Harrington DP. Generalized estimating equations for correlated binary data: Using the odds ratio as a measure of association Biometrika. 78: 153-160. DOI: 10.1093/Biomet/78.1.153  0.333
1991 Laird NM, Louis TA. Smoothing the non-parametric estimate of a prior distribution by roughening. A computational study Computational Statistics and Data Analysis. 12: 27-37. DOI: 10.1016/0167-9473(91)90101-7  0.325
1990 Lipsitz SR, Laird NM, Harrington DP. Maximum likelihood regression methods for paired binary data Statistics in Medicine. 9: 1517-1525. PMID 2281239 DOI: 10.1002/Sim.4780091215  0.331
1990 Laird NM, Fong Wang. Estimating rates of change in randomized clinical trials Controlled Clinical Trials. 11: 405-419. PMID 1963133 DOI: 10.1016/0197-2456(90)90018-W  0.351
1990 Lipsitz SR, Laird NM, Harrington DP. Using the jackknife to estimate the variance of regression estimators from repeated measures studies Communications in Statistics - Theory and Methods. 19: 821-845. DOI: 10.1080/03610929008830234  0.327
1989 Berlin JA, Laird NM, Sacks HS, Chalmers TC. A comparison of statistical methods for combining event rates from clinical trials Statistics in Medicine. 8: 141-151. PMID 2704896 DOI: 10.1002/Sim.4780080202  0.33
1989 Laird NM, Louis TA. Empirical Bayes Ranking Methods Journal of Educational Statistics. 14: 29-46. DOI: 10.3102/10769986014001029  0.35
1989 Laird NM, Louis TA. Empirical Bayes confidence intervals for a series of related experiments Biometrics. 45: 481-495. DOI: 10.2307/2531491  0.369
1989 Lange N, Laird NM. The effect of covariance structure on variance estimation in balanced growth-curve models with random parameters Journal of the American Statistical Association. 84: 241-247. DOI: 10.1080/01621459.1989.10478761  0.355
1988 Laird NM. Missing data in longitudinal studies Statistics in Medicine. 7: 305-315. PMID 3353609 DOI: 10.1002/Sim.4780070131  0.368
1988 Baker SG, Laird NM. Regression analysis for categorical variables with outcome subject to nonignorable nonresponse Journal of the American Statistical Association. 83: 62-69. DOI: 10.1080/01621459.1988.10478565  0.352
1987 Laird NM, Louis TA. Empirical Bayes confidence intervals based on bootstrap samples Journal of the American Statistical Association. 82: 739-750. DOI: 10.1080/01621459.1987.10478490  0.354
1987 Laird N, Lange N, Stram D. Maximum Likelihood Computations with Repeated Measures: Application of the EM Algorithm Journal of the American Statistical Association. 82: 97-105. DOI: 10.1080/01621459.1987.10478395  0.316
1986 Berkey CS, Laird NM. Nonlinear growth curve analysis: Estimating the population parameters Annals of Human Biology. 13: 111-128. PMID 3707041 DOI: 10.1080/03014468600008261  0.31
1984 Stiratelli R, Laird N, Ware JH. Random-Effects Models for Serial Observations with Binary Response Biometrics. 40: 961. DOI: 10.2307/2531147  0.368
1983 DerSimonian R, Laird N. Evaluating the Effect of Coaching on SAT Scores: A Meta-Analysis Harvard Educational Review. 53: 1-15. DOI: 10.17763/Haer.53.1.N06J5H5356217648  0.333
1982 Laird NM, Ware JH. Random-effects models for longitudinal data Biometrics. 38: 963-974. PMID 7168798 DOI: 10.2307/2529876  0.336
1982 Laird NM. Computation of Variance Components Using the EM Algorithm Journal of Statistical Computation and Simulation. 14: 295-303. DOI: 10.1080/00949658208810550  0.314
1981 Laird N, Olivier D. Covariance Analysis of Censored Survival Data Using Log-Linear Analysis Techniques Journal of the American Statistical Association. 76: 231-240. DOI: 10.1080/01621459.1981.10477634  0.334
1978 Laird NM. Empirical Bayes methods for two-way contingency tables Biometrika. 65: 581-590. DOI: 10.1093/Biomet/65.3.581  0.319
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