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Jeremy A. Leonard, Ph.D. - Publications

Affiliations: 
2013 Toxicology North Carolina State University, Raleigh, NC 
Area:
Toxicology, Environmental Sciences, Wildlife Conservation Agriculture
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tan YM, Chan M, Chukwudebe A, Domoradzki J, Fisher J, Hack CE, Hinderliter P, Hirasawa K, Leonard J, Lumen A, Paini A, Qian H, Ruiz P, Wambaugh J, Zhang F, et al. PBPK model reporting template for chemical risk assessment applications. Regulatory Toxicology and Pharmacology : Rtp. 104691. PMID 32502513 DOI: 10.1016/J.Yrtph.2020.104691  0.333
2020 Clewell RA, Leonard JA, Nicolas CI, Campbell J, Yoon M, Efremenko AY, McMullen PD, Andersen ME, Clewell HJ, Phillips KA, Tan YM. Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalates. Toxicology in Vitro : An International Journal Published in Association With Bibra. 104855. PMID 32278033 DOI: 10.1016/J.Tiv.2020.104855  0.418
2019 Leonard JA, Nelms M, Craig E, Perron M, Pope-Varsalona H, Dobreniecki S, Lowit A, Tan YM. A weight of evidence approach to investigate potential common mechanisms in pesticide groups to support cumulative risk assessment: A case study with dinitroaniline pesticides. Regulatory Toxicology and Pharmacology : Rtp. 104419. PMID 31301330 DOI: 10.1016/J.Yrtph.2019.104419  0.332
2019 Paini A, Leonard JA, Joossens E, Bessems JGM, Desalegn A, Dorne JL, Gosling JP, Heringa MB, Klaric M, Kliment T, Kramer NI, Loizou G, Louisse J, Lumen A, Madden JC, et al. Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making. Computational Toxicology (Amsterdam, Netherlands). 9: 61-72. PMID 31008414 DOI: 10.1016/J.Comtox.2018.11.002  0.35
2019 Price P, Leonard J. A proposal for creating a taxonomy of chemical interactions using concepts from the aggregate exposure and adverse outcome pathways Current Opinion in Toxicology. 16: 58-66. DOI: 10.1016/J.Cotox.2019.05.007  0.348
2019 Leonard JA. Supporting systems science through in silico applications: A focus on informing metabolic mechanisms Current Opinion in Toxicology. 16: 1-8. DOI: 10.1016/J.Cotox.2019.03.007  0.389
2019 Leonard JA, Tan Y. Tiered approaches for screening and prioritizing chemicals through integration of pharmacokinetics and exposure information with in vitro dose-response data Computational Toxicology. 12: 100101. DOI: 10.1016/J.Comtox.2019.100101  0.396
2018 Leonard JA, Stevens C, Mansouri K, Chang D, Pudukodu H, Smith S, Tan YM. A Workflow for Identifying Metabolically Active Chemicals to Complement Toxicity Screening. Computational Toxicology (Amsterdam, Netherlands). 6: 71-83. PMID 30246166 DOI: 10.1016/J.Comtox.2017.10.003  0.323
2018 Tan YM, Leonard JA, Edwards S, Teeguarden J, Paini A, Egeghy P. Aggregate Exposure Pathways in Support of Risk Assessment. Current Opinion in Toxicology. 9: 8-13. PMID 29736486 DOI: 10.1016/J.Cotox.2018.03.006  0.402
2018 Tan YM, Leonard JA, Edwards S, Teeguarden J, Egeghy P. Refining the aggregate exposure pathway. Environmental Science. Processes & Impacts. PMID 29465734 DOI: 10.1039/C8Em00018B  0.371
2018 Tan YM, Worley R, Leonard JA, Fisher J. Challenges Associated with Applying Physiologically Based Pharmacokinetic Modeling for Public Health Decision-Making. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29385573 DOI: 10.1093/Toxsci/Kfy010  0.319
2017 Paini A, Leonard JA, Kliment T, Tan YM, Worth A. Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications. Regulatory Toxicology and Pharmacology : Rtp. PMID 28866268 DOI: 10.1016/J.Yrtph.2017.08.019  0.323
2017 Moreau M, Leonard J, Phillips KA, Campbell J, Pendse SN, Nicolas C, Phillips M, Yoon M, Tan YM, Smith S, Pudukodu H, Isaacs K, Clewell H. Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates. Chemosphere. 184: 1194-1201. PMID 28672700 DOI: 10.1016/J.Chemosphere.2017.06.098  0.354
2016 Leonard JA, Cope WG, Hammer EJ, Barnhart MC, Bringolf RB. Extending the toxicity-testing paradigm for freshwater mussels: Assessing chronic reproductive effects of the synthetic estrogen 17α-ethinylestradiol on the unionid mussel Elliptio complanata. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. PMID 27612666 DOI: 10.1016/J.Cbpc.2016.09.002  0.572
2016 Teeguarden JG, Tan YM, Edwards SW, Leonard JA, Anderson KA, Corley RA, Kile ML, L Massey Simonich S, Stone D, Tanguay RL, Waters KM, Harper SL, Williams DE. Expanding on Successful Concepts, Models, and Organization. Environmental Science & Technology. PMID 27509267 DOI: 10.1021/Acs.Est.6B03027  0.41
2016 Archambault JM, Bergeron CM, Cope WG, Lazaro PR, Leonard JA, Shea D. Assessing toxicity of contaminants in riverine suspended sediments to freshwater mussels. Environmental Toxicology and Chemistry / Setac. PMID 27349213 DOI: 10.1002/Etc.3540  0.521
2016 Leonard JA, Sobel Leonard A, Chang D, Edwards S, Lu J, Scholle S, Key P, Winter M, Isaacs KK, Tan YC. Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays. Environmental Science & Technology. PMID 27124219 DOI: 10.1021/Acs.Est.6B00374  0.348
2016 Lu J, Goldsmith MR, Grulke CM, Chang DT, Brooks RD, Leonard JA, Phillips MB, Hypes ED, Fair MJ, Tornero-Velez R, Johnson J, Dary CC, Tan YM. Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction. Plos Computational Biology. 12: e1004495. PMID 26871706 DOI: 10.1371/Journal.Pcbi.1004495  0.341
2016 Teeguarden JG, Tan C, Edwards S, Leonard JA, Anderson KA, Corley RA, Harding A, Kile M, L Massey Simonich S, Stone D, Waters KM, Harper S, Williams DE, Tanguay RL. Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework. Environmental Science & Technology. PMID 26759916 DOI: 10.1021/Acs.Est.5B05311  0.375
2015 Brown K, Phillips M, Grulke C, Yoon M, Young B, McDougall R, Leonard J, Lu J, Lefew W, Tan YM. Reconstructing exposures from biomarkers using exposure-pharmacokinetic modeling - A case study with carbaryl. Regulatory Toxicology and Pharmacology : Rtp. PMID 26545325 DOI: 10.1016/J.Yrtph.2015.10.031  0.39
2015 Phillips MB, Leonard JA, Grulke CM, Chang DT, Edwards SW, Brooks R, Goldsmith MR, El-Masri H, Tan YM. A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways. Environmental Health Perspectives. PMID 25978103 DOI: 10.1289/Ehp.1409450  0.366
2014 Leonard JA, Cope WG, Barnhart MC, Bringolf RB. Metabolomic, behavioral, and reproductive effects of the aromatase inhibitor fadrozole hydrochloride on the unionid mussel Lampsilis fasciola. General and Comparative Endocrinology. 206: 213-26. PMID 25072892 DOI: 10.1016/J.Ygcen.2014.07.019  0.564
2014 Leonard JA, Cope WG, Barnhart MC, Bringolf RB. Metabolomic, behavioral, and reproductive effects of the synthetic estrogen 17 α-ethinylestradiol on the unionid mussel Lampsilis fasciola. Aquatic Toxicology (Amsterdam, Netherlands). 150: 103-16. PMID 24667233 DOI: 10.1016/J.Aquatox.2014.03.004  0.583
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