Yang-Xin Fu - Publications

Affiliations: 
Immunology University of Chicago, Chicago, IL 
Area:
Immunology, Microbiology Biology

263 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wang J, Li S, Wang M, Wang X, Chen S, Sun Z, Ren X, Huang G, Sumer BD, Yan N, Fu YX, Gao J. STING licensing of type I dendritic cells potentiates antitumor immunity. Science Immunology. 9: eadj3945. PMID 38363830 DOI: 10.1126/sciimmunol.adj3945  0.395
2024 Wang J, Li S, Wang M, Wang X, Chen S, Sun Z, Ren X, Huang G, Sumer BD, Yan N, Fu YX, Gao J. STING Licensing of Type I Dendritic Cells Potentiates Antitumor Immunity. Biorxiv : the Preprint Server For Biology. PMID 38260493 DOI: 10.1101/2024.01.02.573934  0.403
2023 Wang X, Liu L, Yue T, Sun Z, Bae J, Tseng KF, Zhang A, Qiao J, Fu YX. Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates dysfunctional CD8 T cells. Signal Transduction and Targeted Therapy. 8: 268. PMID 37433760 DOI: 10.1038/s41392-023-01463-y  0.332
2022 Moore C, Bae J, Liu L, Li H, Fu YX, Qiao J. Exogenous signaling repairs defective T cell signaling inside the tumor microenvironment for better immunity. Jci Insight. 7. PMID 36073543 DOI: 10.1172/jci.insight.159479  0.428
2022 Feng Q, Liu Z, Yu X, Huang T, Chen J, Wang J, Wilhelm J, Li S, Song J, Li W, Sun Z, Sumer BD, Li B, Fu YX, Gao J. Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity. Nature Communications. 13: 4981. PMID 36068198 DOI: 10.1038/s41467-022-32521-8  0.451
2022 Li F, Zhang H, Wang W, Yang P, Huang Y, Zhang J, Yan Y, Wang Y, Ding X, Liang J, Qi X, Li M, Han P, Zhang X, Wang X, ... ... Fu YX, et al. T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies. Nature Communications. 13: 4334. PMID 35882880 DOI: 10.1038/s41467-022-32092-8  0.398
2022 Lee KM, Lin CC, Servetto A, Bae J, Kandagatla V, Ye D, Kim GM, Sudhan DR, Mendiratta S, Gonzalez-Ericsson PI, Balko JM, Lee J, Barnes S, Malladi VS, Tabrizi S, ... ... Fu YX, et al. Epigenetic repression of STING by MYC promotes immune evasion and resistance to immune checkpoint inhibitors in triple negative breast cancer. Cancer Immunology Research. PMID 35561311 DOI: 10.1158/2326-6066.CIR-21-0826  0.323
2022 Li H, Liu Z, Liu L, Zhang H, Han C, Girard L, Park H, Zhang A, Dong C, Ye J, Rayford A, Peyton M, Li X, Avila K, Cao X, ... ... Fu YX, et al. AXL targeting restores PD-1 blockade sensitivity of mutant NSCLC through expansion of TCF1 CD8 T cells. Cell Reports. Medicine. 3: 100554. PMID 35492873 DOI: 10.1016/j.xcrm.2022.100554  0.357
2022 Liu L, Chen J, Zhang H, Ye J, Moore C, Lu C, Fang Y, Fu YX, Li B. Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated antitumor immunity. Nature Cancer. PMID 35393580 DOI: 10.1038/s43018-022-00352-7  0.435
2022 Xue D, Moon B, Liao J, Guo J, Zou Z, Han Y, Cao S, Wang Y, Fu YX, Peng H. A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control established tumors. Science Immunology. 7: eabi6899. PMID 34995098 DOI: 10.1126/sciimmunol.abi6899  0.328
2021 Liu L, Chen J, Bae J, Li H, Sun Z, Moore C, Hsu E, Han C, Qiao J, Fu YX. Rejuvenation of tumour-specific T cells through bispecific antibodies targeting PD-L1 on dendritic cells. Nature Biomedical Engineering. PMID 34725504 DOI: 10.1038/s41551-021-00800-2  0.382
2021 Rao E, Hou Y, Huang X, Wang L, Wang J, Zheng W, Yang H, Yu X, Yang K, Bugno J, Ding X, Vokes E, Fu YX, Weichselbaum RR, Liang HL. All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages. Science Immunology. 6. PMID 34723044 DOI: 10.1126/sciimmunol.aba8426  0.39
2021 Cao X, Liang Y, Hu Z, Li H, Yang J, Hsu EJ, Zhu J, Zhou J, Fu YX. Next generation of tumor-activating type I IFN enhances anti-tumor immune responses to overcome therapy resistance. Nature Communications. 12: 5866. PMID 34620867 DOI: 10.1038/s41467-021-26112-2  0.312
2021 Guo J, Liang Y, Xue D, Shen J, Cai Y, Zhu J, Fu YX, Peng H. Tumor-conditional IL-15 pro-cytokine reactivates anti-tumor immunity with limited toxicity. Cell Research. PMID 34376814 DOI: 10.1038/s41422-021-00543-4  0.306
2021 Zhang A, Ren Z, Tseng KF, Liu X, Li H, Lu C, Cai Y, Minna JD, Fu YX. Dual targeting of CTLA-4 and CD47 on T cells promotes immunity against solid tumors. Science Translational Medicine. 13. PMID 34349035 DOI: 10.1126/scitranslmed.abg8693  0.449
2021 Rodriguez AB, Peske JD, Woods AN, Leick KM, Mauldin IS, Meneveau MO, Young SJ, Lindsay RS, Melssen MM, Cyranowski S, Parriott G, Conaway MR, Fu YX, Slingluff CL, Engelhard VH. Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts. Cell Reports. 36: 109422. PMID 34289373 DOI: 10.1016/j.celrep.2021.109422  0.397
2021 Xue D, Hsu E, Fu YX, Peng H. Next-generation cytokines for cancer immunotherapy. Antibody Therapeutics. 4: 123-133. PMID 34263141 DOI: 10.1093/abt/tbab014  0.301
2021 He Y, Fu L, Li Y, Wang W, Gong M, Zhang J, Dong X, Huang J, Wang Q, Mackay CR, Fu YX, Chen Y, Guo X. Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8 T cell immunity. Cell Metabolism. PMID 33761313 DOI: 10.1016/j.cmet.2021.03.002  0.418
2021 Liang Y, Hannan R, Fu YX. Type I interferon activating type I dendritic cells for anti-tumor immunity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33692027 DOI: 10.1158/1078-0432.CCR-20-2564  0.466
2021 Kolb R, De U, Khan S, Luo Y, Kim MC, Yu H, Wu C, Mo J, Zhang X, Zhang P, Zhang X, Borcherding N, Koppel D, Fu YX, Zheng SG, et al. Proteolysis-targeting chimera against BCL-X destroys tumor-infiltrating regulatory T cells. Nature Communications. 12: 1281. PMID 33627663 DOI: 10.1038/s41467-021-21573-x  0.388
2021 Hou Y, Liang HL, Yu X, Liu Z, Cao X, Rao E, Huang X, Wang L, Li L, Bugno J, Fu Y, Chmura SJ, Wu W, Luo SZ, Zheng W, ... ... Fu YX, et al. Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity. Science Translational Medicine. 13. PMID 33627484 DOI: 10.1126/scitranslmed.abb0130  0.407
2021 Zhang H, Li F, Cao J, Wang X, Cheng H, Qi K, Wang G, Xu K, Zheng J, Fu YX, Yang X. A chimeric antigen receptor with antigen-independent OX40 signaling mediates potent antitumor activity. Science Translational Medicine. 13. PMID 33504651 DOI: 10.1126/scitranslmed.aba7308  0.401
2021 Yang K, Hou Y, Zhang Y, Liang H, Sharma A, Zheng W, Wang L, Torres R, Tatebe K, Chmura SJ, Pitroda SP, Gilbert JA, Fu YX, Weichselbaum RR. Suppression of local type I interferon by gut microbiota-derived butyrate impairs antitumor effects of ionizing radiation. The Journal of Experimental Medicine. 218. PMID 33496784 DOI: 10.1084/jem.20201915  0.392
2021 Son YM, Cheon IS, Wu Y, Li C, Wang Z, Gao X, Chen Y, Takahashi Y, Fu YX, Dent AL, Kaplan MH, Taylor JJ, Cui W, Sun J. Tissue-resident CD4 T helper cells assist the development of protective respiratory B and CD8 T cell memory responses. Science Immunology. 6. PMID 33419791 DOI: 10.1126/sciimmunol.abb6852  0.371
2020 Lu C, Guan J, Lu S, Jin Q, Rousseau B, Lu T, Stephens D, Zhang H, Zhu J, Yang M, Ren Z, Liang Y, Liu Z, Han C, Liu L, ... ... Fu YX, et al. DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity. Cancer Cell. PMID 33338425 DOI: 10.1016/j.ccell.2020.11.006  0.351
2020 Kuo TC, Chen A, Harrabi O, Sockolosky JT, Zhang A, Sangalang E, Doyle LV, Kauder SE, Fontaine D, Bollini S, Han B, Fu YX, Sim J, Pons J, Wan HI. Targeting the myeloid checkpoint receptor SIRPα potentiates innate and adaptive immune responses to promote anti-tumor activity. Journal of Hematology & Oncology. 13: 160. PMID 33256806 DOI: 10.1186/s13045-020-00989-w  0.32
2020 Wang Y, Luo M, Chen Y, Wang Y, Zhang B, Ren Z, Bao L, Wang Y, Wang JE, Fu YX, Luo W, Wang Y. ZMYND8 expression in breast cancer cells blocks T-lymphocyte surveillance to promote tumor growth. Cancer Research. PMID 33148660 DOI: 10.1158/0008-5472.CAN-20-1710  0.34
2020 Zheng W, Ranoa DRE, Huang X, Hou Y, Yang K, Poli EC, Beckett MA, Fu YX, Weichselbaum RR. RIG-I-like receptor LGP2 is required for tumor control by radiation therapy. Cancer Research. PMID 33087322 DOI: 10.1158/0008-5472.CAN-20-2324  0.4
2020 Suresh S, Chen B, Zhu J, Golden RJ, Lu C, Evers BM, Novaresi N, Smith B, Zhan X, Schmid V, Jun S, Karacz CM, Peyton M, Zhong L, Wen Z, ... ... Fu YX, et al. eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer. Nature Cancer. 1: 533-545. PMID 32984844 DOI: 10.1038/S43018-020-0056-0  0.34
2020 Peng Q, Qiu X, Zhang Z, Zhang S, Zhang Y, Liang Y, Guo J, Peng H, Chen M, Fu YX, Tang H. PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade. Nature Communications. 11: 4835. PMID 32973173 DOI: 10.1038/s41467-020-18570-x  0.31
2020 Han C, Liu Z, Zhang Y, Shen A, Dong C, Zhang A, Moore C, Ren Z, Lu C, Cao X, Zhang CL, Qiao J, Fu YX. Author Correction: Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling. Nature Immunology. PMID 32939095 DOI: 10.1038/S41590-020-00805-0  0.422
2020 Beshnova D, Ye J, Onabolu O, Moon B, Zheng W, Fu YX, Brugarolas J, Lea J, Li B. De novo prediction of cancer-associated T cell receptors for noninvasive cancer detection. Science Translational Medicine. 12. PMID 32817363 DOI: 10.1126/Scitranslmed.Aaz3738  0.376
2020 Wang W, Li Y, Hao J, He Y, Dong X, Fu YX, Guo X. The Interaction between Lymphoid Tissue Inducer-Like Cells and T Cells in the Mesenteric Lymph Node Restrains Intestinal Humoral Immunity. Cell Reports. 32: 107936. PMID 32698011 DOI: 10.1016/J.Celrep.2020.107936  0.495
2020 Mender I, Zhang A, Ren Z, Han C, Deng Y, Siteni S, Li H, Zhu J, Vemula A, Shay JW, Fu YX. Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity. Cancer Cell. PMID 32619407 DOI: 10.1016/J.Ccell.2020.05.020  0.479
2020 Qiao J, Fu YX. Cytokines that target immune killer cells against tumors. Cellular & Molecular Immunology. PMID 32523115 DOI: 10.1038/s41423-020-0481-0  0.355
2020 Zhang F, Manna S, Pop LM, Chen ZJ, Fu YX, Hannan R. Type I Interferon Response in Radiation-Induced Anti-Tumor Immunity. Seminars in Radiation Oncology. 30: 129-138. PMID 32381292 DOI: 10.1016/J.Semradonc.2019.12.009  0.46
2020 Deng S, Sun Z, Qiao J, Liang Y, Liu L, Dong C, Shen A, Wang Y, Tang H, Fu YX, Peng H. Targeting tumors with IL-21 reshapes the tumor microenvironment by proliferating PD-1intTim-3-CD8+ T cells. Jci Insight. 5. PMID 32271164 DOI: 10.1172/Jci.Insight.132000  0.314
2020 Sun Z, Ren Z, Yang K, Liu Z, Cao S, Deng S, Xu L, Liang Y, Guo J, Bian Y, Xu H, Shi J, Wang F, Fu YX, Peng H. Author Correction: A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 T-cell response and effective tumor control. Nature Communications. 11: 1716. PMID 32238807 DOI: 10.1038/S41467-020-15532-1  0.448
2020 Han C, Liu Z, Zhang Y, Shen A, Dong C, Zhang A, Moore C, Ren Z, Lu C, Cao X, Zhang CL, Qiao J, Fu YX. Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling. Nature Immunology. PMID 32231300 DOI: 10.1038/S41590-020-0641-5  0.404
2020 Liu Z, Fu YX. Chemotherapy Induces Cancer-Fighting B Cells. Cell. PMID 32142652 DOI: 10.1016/j.cell.2020.02.046  0.423
2020 Shi Y, Zheng W, Yang K, Harris KG, Ni K, Xue L, Lin W, Chang EB, Weichselbaum RR, Fu YX. Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling. The Journal of Experimental Medicine. 217. PMID 32142585 DOI: 10.1084/Jem.20192282  0.468
2020 Wang W, Zhou X, Bian Y, Wang S, Chai Q, Guo Z, Wang Z, Zhu P, Peng H, Yan X, Li W, Fu YX, Zhu M. Dual-targeting nanoparticle vaccine elicits a therapeutic antibody response against chronic hepatitis B. Nature Nanotechnology. PMID 32123380 DOI: 10.1038/S41565-020-0648-Y  0.31
2020 Zhang A, Mender I, Ren Z, Han C, Deng Y, Siteni S, Li H, Shay JW, Fu Y. Abstract 973: Telomere stress potentiates host STING-dependent anti-tumor immunity Immunology. 80: 973-973. DOI: 10.1158/1538-7445.Am2020-973  0.469
2019 Liu Z, Han C, Fu YX. Targeting innate sensing in the tumor microenvironment to improve immunotherapy. Cellular & Molecular Immunology. PMID 31844141 DOI: 10.1038/S41423-019-0341-Y  0.463
2019 Li B, Zhang H, Liu L, Zhang J, Chen J, Ye J, Shukla SA, Qiao J, Zhan X, Chen H, Wu CJ, Fu YX. Investigation of antigen-specific T cell receptor clusters in human cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31831563 DOI: 10.1158/1078-0432.Ccr-19-3249  0.341
2019 Arina A, Beckett M, Fernandez C, Zheng W, Pitroda S, Chmura SJ, Luke JJ, Forde M, Hou Y, Burnette B, Mauceri H, Lowy I, Sims T, Khodarev N, Fu YX, et al. Tumor-reprogrammed resident T cells resist radiation to control tumors. Nature Communications. 10: 3959. PMID 31477729 DOI: 10.1038/S41467-019-11906-2  0.82
2019 Sun Z, Ren Z, Yang K, Liu Z, Cao S, Deng S, Xu L, Liang Y, Guo J, Bian Y, Xu H, Shi J, Wang F, Fu YX, Peng H. A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 T-cell response and effective tumor control. Nature Communications. 10: 3874. PMID 31462678 DOI: 10.1038/S41467-019-11782-W  0.427
2019 Liu Z, Han C, Dong C, Shen A, Hsu E, Ren Z, Lu C, Liu L, Zhang A, Timmerman C, Pu Y, Wang Y, Chen M, Qiao J, Fu YX. Hypofractionated EGFR tyrosine kinase inhibitor limits tumor relapse through triggering innate and adaptive immunity. Science Immunology. 4. PMID 31399492 DOI: 10.1126/sciimmunol.aav6473  0.309
2019 Li X, Liu Z, Zhang A, Han C, Shen A, Jiang L, Boothman DA, Qiao J, Wang Y, Huang X, Fu YX. NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance. Nature Communications. 10: 3251. PMID 31324798 DOI: 10.1038/S41467-019-11238-1  0.37
2019 Qiao J, Liu Z, Dong C, Luan Y, Zhang A, Moore C, Fu K, Peng J, Wang Y, Ren Z, Han C, Xu T, Fu YX. Targeting Tumors with IL-10 Prevents Dendritic Cell-Mediated CD8 T Cell Apoptosis. Cancer Cell. 35: 901-915.e4. PMID 31185213 DOI: 10.1016/J.Ccell.2019.05.005  0.435
2019 Ye C, Li Q, Li X, Park CG, He Y, Zhang Y, Wu B, Xue Y, Yang K, Lv Y, Ying XL, Ding HH, Cai H, Alkraiem AA, Njiri O, ... ... Fu Y, et al. interacts with CD209 receptors to promote host dissemination and infection. Infection and Immunity. PMID 31085704 DOI: 10.1128/Iai.00100-19  0.333
2019 Wang Y, Du X, Wei J, Long L, Tan H, Guy C, Dhungana Y, Qian C, Neale G, Fu YX, Yu J, Peng J, Chi H. LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity. Cell Research. PMID 30911060 DOI: 10.1038/S41422-019-0157-4  0.376
2019 Wang GZ, Zhang L, Zhao XC, Gao SH, Qu LW, Yu H, Fang WF, Zhou YC, Liang F, Zhang C, Huang YC, Liu Z, Fu YX, Zhou GB. The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy. Nature Communications. 10: 1125. PMID 30850589 DOI: 10.1038/S41467-019-08887-7  0.354
2019 Luo M, Liu Z, Zhang X, Han C, Samandi LZ, Dong C, Sumer BD, Lea J, Fu YX, Gao J. Synergistic STING activation by PC7A nanovaccine and ionizing radiation improves cancer immunotherapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30844475 DOI: 10.1016/J.Jconrel.2019.02.036  0.411
2018 Sun Z, Fu YX, Peng H. Targeting tumor cells with antibodies enhances anti-tumor immunity. Biophysics Reports. 4: 243-253. PMID 30533489 DOI: 10.1007/S41048-018-0070-2  0.469
2018 Yang K, Liang Y, Sun Z, Liu L, Liao J, Xu H, Zhu M, Fu YX, Peng H. T cell-derived lymphotoxin limits Th1 response during HSV-1 infection. Scientific Reports. 8: 17727. PMID 30531962 DOI: 10.1038/S41598-018-36012-Z  0.493
2018 He YX, Ye CL, Zhang P, Li Q, Park CG, Yang K, Jiang LY, Lv Y, Ying XL, Ding HH, Huang HP, Tembo JM, Li AY, Cheng B, Zhang SS, ... ... Fu YX, et al. exploits CD209 receptors for promoting host dissemination and infection. Infection and Immunity. PMID 30348825 DOI: 10.1128/Iai.00654-18  0.348
2018 Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, He L, Chen Y, Chen H, Luo W, Lu Z, Xie J, Churchill H, Xu Y, Zhou Z, ... ... Fu YX, et al. LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. Nature. PMID 30333625 DOI: 10.1038/S41586-018-0615-Z  0.481
2018 Hou Y, Liang H, Rao E, Zheng W, Huang X, Deng L, Zhang Y, Yu X, Xu M, Mauceri H, Arina A, Weichselbaum RR, Fu YX. Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Immunity. PMID 30170810 DOI: 10.1016/J.Immuni.2018.07.008  0.385
2018 Tang H, Qiu X, Timmerman C, Fu YX. Targeting Tertiary Lymphoid Structures for Tumor Immunotherapy. Methods in Molecular Biology (Clifton, N.J.). 1845: 275-286. PMID 30141019 DOI: 10.1007/978-1-4939-8709-2_16  0.449
2018 Liu X, Liu L, Ren Z, Yang K, Xu H, Luan Y, Fu K, Guo J, Peng H, Zhu M, Fu YX. Dual Targeting of Innate and Adaptive Checkpoints on Tumor Cells Limits Immune Evasion. Cell Reports. 24: 2101-2111. PMID 30134171 DOI: 10.1016/j.celrep.2018.07.062  0.379
2018 Cai Y, Xue F, Quan C, Qu M, Liu N, Zhang Y, Fleming C, Hu X, Zhang HG, Weichselbaum R, Fu YX, Tieri D, Rouchka EC, Zheng J, Yan J. A Critical Role of the IL-1β-IL-1R Signaling Pathway in Skin Inflammation and Psoriasis Pathogenesis. The Journal of Investigative Dermatology. PMID 30120937 DOI: 10.1016/J.Jid.2018.07.025  0.309
2018 Yang K, Liang Y, Sun Z, Xue D, Xu H, Zhu M, Fu YX, Peng H. T cell-derived Lymphotoxin is Essential for anti-HSV-1 Humoral Immune Response. Journal of Virology. PMID 29743364 DOI: 10.1128/JVI.00428-18  0.434
2018 Tang H, Fu YX. Immune Evasion in Tumor's Own Sweet Way. Cell Metabolism. PMID 29628418 DOI: 10.1016/j.cmet.2018.03.013  0.344
2018 Zhang CC, Fu YX. Another way to not get eaten. Nature Immunology. 19: 6-7. PMID 29242546 DOI: 10.1038/S41590-017-0009-7  0.361
2018 Fu Y, Liu X. Abstract 4557: Dual targeting of innate and adaptive checkpoints on tumor cells limits immune evasion Cancer Research. 78: 4557-4557. DOI: 10.1158/1538-7445.Am2018-4557  0.507
2018 Liu Z, Han C, Shen A, Dong C, Qiao J, Fu Y. Abstract 2752: EGFR tyrosine kinase inhibitor limits tumor relapse through enhancing anti-tumor T cell responses Cancer Research. 78: 2752-2752. DOI: 10.1158/1538-7445.Am2018-2752  0.399
2017 Liang H, Deng L, Hou Y, Meng X, Huang X, Rao E, Zheng W, Mauceri H, Mack M, Xu M, Fu YX, Weichselbaum RR. Host STING-dependent MDSC mobilization drives extrinsic radiation resistance. Nature Communications. 8: 1736. PMID 29170400 DOI: 10.1038/s41467-017-01566-5  0.305
2017 Xu MM, Pu Y, Han D, Shi Y, Cao X, Liang H, Chen X, Li XD, Deng L, Chen ZJ, Weichselbaum RR, Fu YX. Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling. Immunity. PMID 28801234 DOI: 10.1016/j.immuni.2017.07.016  0.318
2017 Weinstein AM, Chen L, Brzana EA, Patil PR, Taylor JL, Fabian KL, Wallace CT, Jones SD, Watkins SC, Lu B, Stroncek DF, Denning TL, Fu YX, Cohen PA, Storkus WJ. Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment. Oncoimmunology. 6: e1322238. PMID 28680760 DOI: 10.1080/2162402X.2017.1322238  0.319
2017 Zhang Y, Kim TJ, Wroblewska JA, Tesic V, Upadhyay V, Weichselbaum RR, Tumanov AV, Tang H, Guo X, Tang H, Fu YX. Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation. Cellular & Molecular Immunology. PMID 28579615 DOI: 10.1038/Cmi.2017.25  0.594
2017 Liao J, Luan Y, Ren Z, Liu X, Xue D, Xu H, Sun Z, Yang K, Peng H, Fu YX. Converting lymphoma cells into potent antigen-presenting cells for interferon-induced tumor regression. Cancer Immunology Research. PMID 28533311 DOI: 10.1158/2326-6066.CIR-16-0221  0.368
2017 Bian Y, Zhang Z, Sun Z, Zhao J, Zhu D, Wang Y, Fu S, Guo J, Liu L, Su L, Wang FS, Fu YX, Peng H. Vaccines Targeting PreS1 Domain Overcome Immune Tolerance in HBV Carrier Mice. Hepatology (Baltimore, Md.). PMID 28445927 DOI: 10.1002/Hep.29239  0.303
2017 Luo M, Wang H, Wang Z, Cai H, Lu Z, Li Y, Du M, Huang G, Wang C, Chen X, Porembka MR, Lea J, Frankel AE, Fu YX, Chen ZJ, et al. A STING-activating nanovaccine for cancer immunotherapy. Nature Nanotechnology. PMID 28436963 DOI: 10.1038/Nnano.2017.52  0.307
2017 Qiao G, Qin J, Kunda N, Calata J, Mahmud D, Gann PH, Fu YX, Rosenberg SA, Prabhakar BS, Maker AV. LIGHT elevation enhances immune eradication of colon cancer metastases. Cancer Research. PMID 28249900 DOI: 10.1158/0008-5472.Can-16-1655  0.359
2017 Weichselbaum RR, Liang H, Deng L, Fu YX. Radiotherapy and immunotherapy: a beneficial liaison? Nature Reviews. Clinical Oncology. PMID 28094262 DOI: 10.1038/nrclinonc.2016.211  0.31
2017 Liu X, Kwon H, Li Z, Fu YX. Is CD47 an innate immune checkpoint for tumor evasion? Journal of Hematology & Oncology. 10: 12. PMID 28077173 DOI: 10.1186/S13045-016-0381-Z  0.44
2016 Spiotto M, Fu YX, Weichselbaum RR. The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications. Science Immunology. 1. PMID 28018989 DOI: 10.1126/Sciimmunol.Aag1266  0.539
2016 Ascierto PA, Agarwala S, Botti G, Cesano A, Ciliberto G, Davies MA, Demaria S, Dummer R, Eggermont AM, Ferrone S, Fu YX, Gajewski TF, Garbe C, Huber V, Khleif S, et al. Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015. Journal of Translational Medicine. 14: 313. PMID 27846884 DOI: 10.1186/S12967-016-1070-Y  0.372
2016 Shi Y, Wu W, Chai Q, Li Q, Hou Y, Xia H, Ren B, Xu H, Guo X, Jin C, Lv M, Wang Z, Fu YX, Zhu M. LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration. Nature Communications. 7: 12369. PMID 27493002 DOI: 10.1038/Ncomms12369  0.451
2016 Ren Z, Guo J, Liao J, Luan Y, Liu Z, Sun Z, Liu X, Liang Y, Peng H, Fu YX. CTLA-4 limits anti-CD20-mediated tumor regression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27354469 DOI: 10.1158/1078-0432.CCR-16-0040  0.352
2016 Zheng H, Zou W, Shen J, Xu L, Wang S, Fu YX, Fan W. Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth. Stem Cells Translational Medicine. PMID 27352928 DOI: 10.5966/Sctm.2015-0300  0.35
2016 Zheng W, Skowron KB, Namm JP, Burnette B, Fernandez C, Arina A, Liang H, Spiotto MT, Posner MC, Fu YX, Weichselbaum RR. Combination of radiotherapy and vaccination overcome checkpoint blockade resistance. Oncotarget. PMID 27343548 DOI: 10.18632/Oncotarget.9915  0.801
2016 Ren Z, Peng H, Fu YX. PD-1 Shapes B Cells as Evildoers in the Tumor Microenvironment. Cancer Discovery. 6: 477-478. PMID 27138562 DOI: 10.1158/2159-8290.Cd-16-0307  0.349
2016 Tang H, Wang Y, Chlewicki LK, Zhang Y, Guo J, Liang W, Wang J, Wang X, Fu YX. Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade. Cancer Cell. 29: 285-296. PMID 26977880 DOI: 10.1016/j.ccell.2016.02.004  0.429
2016 Tang H, Wang Y, Fu Y. Abstract A088: Increase lymphocyte infiltration overcomes tumor resistance to checkpoint blockade Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A088  0.502
2016 Tang H, Qiu X, Wang Y, Fu Y. Abstract A112: Manipulating tumor microenvironment for immunotherapy Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A112  0.455
2016 Zheng W, Skowron KB, Namm JP, Burnette B, Fernandez C, Arina A, Liang H, Spiotto MT, Posner MC, Fu Y, Weichselbaum RR. Abstract LB-251: Radiotherapy sensitizes pancreatic cancer to immunotherapy by promoting T cell infiltration Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-251  0.807
2015 Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, Minze L, Fu YX, Ghobrial RM, Liu W, Li XC. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nature Communications. 6: 8266. PMID 26365427 DOI: 10.1038/ncomms9266  0.385
2015 Deng L, Liang H, Fu S, Weichselbaum RR, Fu YX. From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26362999 DOI: 10.1158/1078-0432.CCR-14-3110  0.352
2015 Liu X, Pu Y, Cron K, Deng L, Kline J, Frazier WA, Xu H, Peng H, Fu YX, Xu MM. CD47 blockade triggers T cell-mediated destruction of immunogenic tumors. Nature Medicine. PMID 26322579 DOI: 10.1038/Nm.3931  0.413
2015 Li H, Fu YX, Wu Q, Zhou Y, Crossman DK, Yang P, Li J, Luo B, Morel LM, Kabarowski JH, Yagita H, Ware CF, Hsu HC, Mountz JD. Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus. The Journal of Clinical Investigation. PMID 26098211 DOI: 10.1172/Jci81059  0.397
2015 Okwor I, Xu G, Tang H, Liang Y, Fu YX, Uzonna JE. Deficiency of CD40 Reveals an Important Role for LIGHT in Anti-Leishmania Immunity. Journal of Immunology (Baltimore, Md. : 1950). 195: 194-202. PMID 26026056 DOI: 10.4049/jimmunol.1401892  0.351
2015 Peske JD, Thompson ED, Gemta L, Baylis RA, Fu YX, Engelhard VH. Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity. Nature Communications. 6: 7114. PMID 25968334 DOI: 10.1038/Ncomms8114  0.404
2015 Kumar V, Dasoveanu DC, Chyou S, Tzeng TC, Rozo C, Liang Y, Stohl W, Fu YX, Ruddle NH, Lu TT. A dendritic-cell-stromal axis maintains immune responses in lymph nodes. Immunity. 42: 719-30. PMID 25902483 DOI: 10.1016/J.Immuni.2015.03.015  0.319
2015 Xu M, Liu M, Du X, Li S, Li H, Li X, Li Y, Wang Y, Qin Z, Fu YX, Wang S. Intratumoral Delivery of IL-21 Overcomes Anti-Her2/Neu Resistance through Shifting Tumor-Associated Macrophages from M2 to M1 Phenotype. Journal of Immunology (Baltimore, Md. : 1950). 194: 4997-5006. PMID 25876763 DOI: 10.4049/jimmunol.1402603  0.303
2015 Tu TC, Brown NK, Kim TJ, Wroblewska J, Yang X, Guo X, Lee SH, Kumar V, Lee KM, Fu YX. CD160 is essential for NK-mediated IFN-γ production. The Journal of Experimental Medicine. 212: 415-29. PMID 25711213 DOI: 10.1084/Jem.20131601  0.706
2015 Ma SY, Song H, Park JH, Choi JH, Kim JH, Kim KH, Park S, Park DH, Kang MS, Kwak M, Fu YX, Choi I, Cho H, Park S. Addition of anti-neu antibody to local irradiation can improve tumor-bearing BALB/c mouse survival through immune-mediated mechanisms. Radiation Research. 183: 271-8. PMID 25706775 DOI: 10.1667/Rr13800.1  0.426
2015 Macho-Fernandez E, Koroleva EP, Spencer CM, Tighe M, Torrado E, Cooper AM, Fu YX, Tumanov AV. Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells. Mucosal Immunology. 8: 403-13. PMID 25183367 DOI: 10.1038/Mi.2014.78  0.391
2015 Fu Y. Abstract SY39-03: Radiation-mediated DNA sensing pathway for immunity and tumor regression Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy39-03  0.479
2014 Deng L, Liang H, Xu M, Yang X, Burnette B, Arina A, Li XD, Mauceri H, Beckett M, Darga T, Huang X, Gajewski TF, Chen ZJ, Fu YX, Weichselbaum RR. STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors. Immunity. 41: 843-52. PMID 25517616 DOI: 10.1016/J.Immuni.2014.10.019  0.793
2014 Spaapen RM, Leung MY, Fuertes MB, Kline JP, Zhang L, Zheng Y, Fu YX, Luo X, Cohen KS, Gajewski TF. Therapeutic activity of high-dose intratumoral IFN-β requires direct effect on the tumor vasculature. Journal of Immunology (Baltimore, Md. : 1950). 193: 4254-60. PMID 25217157 DOI: 10.4049/jimmunol.1401109  0.373
2014 Song H, Kim TO, Ma SY, Park JH, Choi JH, Kim JH, Kang MS, Bae SK, Kim KH, Kim TH, Seo SK, Choi IW, Song GA, Mortenson ED, Fu YX, et al. Intratumoral heterogeneity impacts the response to anti-neu antibody therapy. Bmc Cancer. 14: 647. PMID 25179116 DOI: 10.1186/1471-2407-14-647  0.373
2014 Stefka AT, Feehley T, Tripathi P, Qiu J, McCoy K, Mazmanian SK, Tjota MY, Seo GY, Cao S, Theriault BR, Antonopoulos DA, Zhou L, Chang EB, Fu YX, Nagler CR. Commensal bacteria protect against food allergen sensitization. Proceedings of the National Academy of Sciences of the United States of America. 111: 13145-50. PMID 25157157 DOI: 10.1073/Pnas.1412008111  0.314
2014 Deng L, Liang H, Burnette B, Weicheslbaum RR, Fu YX. Radiation and anti-PD-L1 antibody combinatorial therapy induces T cell-mediated depletion of myeloid-derived suppressor cells and tumor regression. Oncoimmunology. 3: e28499. PMID 25050217 DOI: 10.4161/Onci.28499  0.806
2014 Yang X, Zhang X, Sun Y, Tu T, Fu ML, Miller M, Fu YX. A BTLA-mediated bait and switch strategy permits Listeria expansion in CD8α(+) DCs to promote long-term T cell responses. Cell Host & Microbe. 16: 68-80. PMID 25011109 DOI: 10.1016/J.Chom.2014.05.021  0.805
2014 Kim TJ, Upadhyay V, Kumar V, Lee KM, Fu YX. Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment. The Journal of Experimental Medicine. 211: 1421-31. PMID 24913234 DOI: 10.1084/Jem.20131501  0.624
2014 Kohrt HE, Colevas AD, Houot R, Weiskopf K, Goldstein MJ, Lund P, Mueller A, Sagiv-Barfi I, Marabelle A, Lira R, Troutner E, Richards L, Rajapaska A, Hebb J, Chester C, ... ... Fu YX, et al. Targeting CD137 enhances the efficacy of cetuximab. The Journal of Clinical Investigation. 124: 2668-82. PMID 24837434 DOI: 10.1172/Jci73014  0.329
2014 Zhao J, Zhang Z, Luan Y, Zou Z, Sun Y, Li Y, Jin L, Zhou C, Fu J, Gao B, Fu Y, Wang FS. Pathological functions of interleukin-22 in chronic liver inflammation and fibrosis with hepatitis B virus infection by promoting T helper 17 cell recruitment. Hepatology (Baltimore, Md.). 59: 1331-42. PMID 24677193 DOI: 10.1002/Hep.26916  0.35
2014 Bility MT, Cheng L, Zhang Z, Luan Y, Li F, Chi L, Zhang L, Tu Z, Gao Y, Fu Y, Niu J, Wang F, Su L. Hepatitis B virus infection and immunopathogenesis in a humanized mouse model: induction of human-specific liver fibrosis and M2-like macrophages. Plos Pathogens. 10: e1004032. PMID 24651854 DOI: 10.1371/Journal.Ppat.1004032  0.316
2014 Mortenson ED, Fu YX. Anti-HER2/Neu passive-aggressive immunotherapy. Oncoimmunology. 3: e27296. PMID 24605268 DOI: 10.4161/Onci.27296  0.465
2014 Ma F, Feng J, Zhang C, Li Y, Qi G, Li H, Wu Y, Fu Y, Zhao Y, Chen H, Du J, Tang H. The requirement of CD8+ T cells to initiate and augment acute cardiac inflammatory response to high blood pressure. Journal of Immunology (Baltimore, Md. : 1950). 192: 3365-73. PMID 24600037 DOI: 10.4049/Jimmunol.1301522  0.445
2014 Yang X, Zhang X, Fu ML, Weichselbaum RR, Gajewski TF, Guo Y, Fu YX. Targeting the tumor microenvironment with interferon-β bridges innate and adaptive immune responses. Cancer Cell. 25: 37-48. PMID 24434209 DOI: 10.1016/J.Ccr.2013.12.004  0.422
2014 Guo X, Qiu J, Tu T, Yang X, Deng L, Anders RA, Zhou L, Fu YX. Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection. Immunity. 40: 25-39. PMID 24412612 DOI: 10.1016/J.Immuni.2013.10.021  0.69
2014 Upadhyay V, Fu YX. Lymphotoxin organizes contributions to host defense and metabolic illness from innate lymphoid cells. Cytokine & Growth Factor Reviews. 25: 227-33. PMID 24411493 DOI: 10.1016/J.Cytogfr.2013.12.007  0.559
2014 Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum RR, Fu YX. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. The Journal of Clinical Investigation. 124: 687-95. PMID 24382348 DOI: 10.1172/Jci67313  0.808
2014 Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum R, Fu Y. Abstract 5019: Irradiation and anti-B7-H1 provide synergistic treatment effects in murine cancer Cancer Research. 74: 5019-5019. DOI: 10.1158/1538-7445.Am2014-5019  0.814
2013 Binder DC, Engels B, Arina A, Yu P, Slauch JM, Fu YX, Karrison T, Burnette B, Idel C, Zhao M, Hoffman RM, Munn DH, Rowley DA, Schreiber H. Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer. Cancer Immunology Research. 1: 123-33. PMID 24455752 DOI: 10.1158/2326-6066.Cir-13-0058  0.806
2013 Liang H, Deng L, Burnette B, Weichselbaum RR, Fu YX. Radiation-induced tumor dormancy reflects an equilibrium between the proliferation and T lymphocyte-mediated death of malignant cells. Oncoimmunology. 2: e25668. PMID 24319637 DOI: 10.4161/Onci.25668  0.829
2013 Gajewski TF, Schreiber H, Fu YX. Innate and adaptive immune cells in the tumor microenvironment. Nature Immunology. 14: 1014-22. PMID 24048123 DOI: 10.1038/Ni.2703  0.456
2013 Qiu J, Guo X, Chen ZM, He L, Sonnenberg GF, Artis D, Fu YX, Zhou L. Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora. Immunity. 39: 386-99. PMID 23954130 DOI: 10.1016/J.Immuni.2013.08.002  0.479
2013 Obeid E, Nanda R, Fu YX, Olopade OI. The role of tumor-associated macrophages in breast cancer progression (review). International Journal of Oncology. 43: 5-12. PMID 23673510 DOI: 10.3892/Ijo.2013.1938  0.332
2013 Upadhyay V, Fu YX. Linking the microbiota and metabolic disease with lymphotoxin. International Immunology. 25: 397-403. PMID 23657002 DOI: 10.1093/Intimm/Dxt018  0.588
2013 Liang H, Deng L, Chmura S, Burnette B, Liadis N, Darga T, Beckett MA, Lingen MW, Witt M, Weichselbaum RR, Fu YX. Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell-mediated killing. Journal of Immunology (Baltimore, Md. : 1950). 190: 5874-81. PMID 23630355 DOI: 10.4049/Jimmunol.1202612  0.821
2013 Su L, Nalle SC, Shen L, Turner ES, Singh G, Breskin LA, Khramtsova EA, Khramtsova G, Tsai PY, Fu YX, Abraham C, Turner JR. TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. Gastroenterology. 145: 407-15. PMID 23619146 DOI: 10.1053/J.Gastro.2013.04.011  0.392
2013 Upadhyay V, Fu YX, Bromberg JS. From infection to colonization: the role of microbiota in transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 829. PMID 23551627 DOI: 10.1111/ajt.12232  0.461
2013 Upadhyay V, Fu YX. Lymphotoxin signalling in immune homeostasis and the control of microorganisms. Nature Reviews. Immunology. 13: 270-9. PMID 23524463 DOI: 10.1038/Nri3406  0.624
2013 Mortenson ED, Fu YX. Adaptive Immune Responses and HER2/neu Positive Breast Cancer. Current Pathobiology Reports. 1: 37-42. PMID 23420038 DOI: 10.1007/S40139-012-0001-8  0.336
2013 Mortenson ED, Park S, Jiang Z, Wang S, Fu YX. Effective anti-neu-initiated antitumor responses require the complex role of CD4+ T cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1476-86. PMID 23363817 DOI: 10.1158/1078-0432.Ccr-12-2522  0.506
2013 Chellan B, Koroleva EP, Sontag TJ, Tumanov AV, Fu YX, Getz GS, Reardon CA. LIGHT/TNFSR14 can regulate hepatic lipase expression by hepatocytes independent of T cells and Kupffer cells. Plos One. 8: e54719. PMID 23355893 DOI: 10.1371/Journal.Pone.0054719  0.399
2013 Fuertes MB, Woo SR, Burnett B, Fu YX, Gajewski TF. Type I interferon response and innate immune sensing of cancer. Trends in Immunology. 34: 67-73. PMID 23122052 DOI: 10.1016/j.it.2012.10.004  0.373
2013 Yang X, Zhang X, Mortenson ED, Radkevich-Brown O, Wang Y, Fu YX. Cetuximab-mediated tumor regression depends on innate and adaptive immune responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 91-100. PMID 22990672 DOI: 10.1038/mt.2012.184  0.396
2012 Burnette B, Fu YX, Weichselbaum RR. The confluence of radiotherapy and immunotherapy. Frontiers in Oncology. 2: 143. PMID 23087904 DOI: 10.3389/Fonc.2012.00143  0.778
2012 Upadhyay V, Poroyko V, Kim TJ, Devkota S, Fu S, Liu D, Tumanov AV, Koroleva EP, Deng L, Nagler C, Chang EB, Tang H, Fu YX. Lymphotoxin regulates commensal responses to enable diet-induced obesity. Nature Immunology. 13: 947-53. PMID 22922363 DOI: 10.1038/Ni.2403  0.574
2012 Xiao X, Balasubramanian S, Liu W, Chu X, Wang H, Taparowsky EJ, Fu YX, Choi Y, Walsh MC, Li XC. OX40 signaling favors the induction of T(H)9 cells and airway inflammation. Nature Immunology. 13: 981-90. PMID 22842344 DOI: 10.1038/Ni.2390  0.338
2012 Xu M, Du X, Liu M, Li S, Li X, Fu YX, Wang S. The tumor immunosuppressive microenvironment impairs the therapy of anti-HER2/neu antibody. Protein & Cell. 3: 441-9. PMID 22717982 DOI: 10.1007/s13238-012-2044-3  0.428
2012 Zou W, Zheng H, He TC, Chang J, Fu YX, Fan W. LIGHT delivery to tumors by mesenchymal stem cells mobilizes an effective antitumor immune response. Cancer Research. 72: 2980-9. PMID 22511579 DOI: 10.1158/0008-5472.Can-11-4216  0.503
2012 Oh SS, Moon C, Kim DH, Song H, Park S, Fu Y, Kim KD. Adenovirally delivered IFN-β exerts antitumor effects through transient T-lymphocyte depletion and Ag-specific T-cell proliferation. International Journal of Molecular Medicine. 29: 1153-7. PMID 22426464 DOI: 10.3892/Ijmm.2012.936  0.491
2012 Moseman EA, Iannacone M, Bosurgi L, Tonti E, Chevrier N, Tumanov A, Fu YX, Hacohen N, von Andrian UH. B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity. Immunity. 36: 415-26. PMID 22386268 DOI: 10.1016/J.Immuni.2012.01.013  0.303
2012 Meng Y, Efimova EV, Hamzeh KW, Darga TE, Mauceri HJ, Fu YX, Kron SJ, Weichselbaum RR. Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1046-55. PMID 22334019 DOI: 10.1038/Mt.2012.19  0.453
2012 Yang X, Mortenson ED, Fu YX. Targeting and utilizing primary tumors as live vaccines: changing strategies. Cellular & Molecular Immunology. 9: 20-6. PMID 22101245 DOI: 10.1038/Cmi.2011.49  0.428
2011 Zhu M, Fu YX. The role of core TNF/LIGHT family members in lymph node homeostasis and remodeling. Immunological Reviews. 244: 75-84. PMID 22017432 DOI: 10.1111/J.1600-065X.2011.01061.X  0.364
2011 Zhu M, Fu Y. Proinflammatory IL-17 induces iBALT development. Cellular & Molecular Immunology. 9: 101-2. PMID 21927015 DOI: 10.1038/Cmi.2011.46  0.408
2011 Tumanov AV, Koroleva EP, Guo X, Wang Y, Kruglov A, Nedospasov S, Fu YX. Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge. Cell Host & Microbe. 10: 44-53. PMID 21767811 DOI: 10.1016/J.Chom.2011.06.002  0.352
2011 Zhang Z, Xu X, Lu J, Zhang S, Gu L, Fu J, Jin L, Li H, Zhao M, Zhang J, Wu H, Su L, Fu YX, Wang FS. B and T lymphocyte attenuator down-regulation by HIV-1 depends on type I interferon and contributes to T-cell hyperactivation. The Journal of Infectious Diseases. 203: 1668-78. PMID 21592997 DOI: 10.1093/Infdis/Jir165  0.418
2011 Lasaro MO, Sazanovich M, Giles-Davis W, Mrass P, Bunte RM, Sewell DA, Hussain SF, Fu YX, Weninger W, Paterson Y, Ertl HC. Active immunotherapy combined with blockade of a coinhibitory pathway achieves regression of large tumor masses in cancer-prone mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1727-36. PMID 21587210 DOI: 10.1038/Mt.2011.88  0.377
2011 Zhu M, Yang Y, Wang Y, Wang Z, Fu YX. LIGHT regulates inflamed draining lymph node hypertrophy. Journal of Immunology (Baltimore, Md. : 1950). 186: 7156-63. PMID 21572030 DOI: 10.4049/Jimmunol.1002097  0.441
2011 Jang IK, Cronshaw DG, Xie LK, Fang G, Zhang J, Oh H, Fu YX, Gu H, Zou Y. Growth-factor receptor-bound protein-2 (Grb2) signaling in B cells controls lymphoid follicle organization and germinal center reaction. Proceedings of the National Academy of Sciences of the United States of America. 108: 7926-31. PMID 21508326 DOI: 10.1073/Pnas.1016451108  0.393
2011 Burnette BC, Liang H, Lee Y, Chlewicki L, Khodarev NN, Weichselbaum RR, Fu YX, Auh SL. The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity. Cancer Research. 71: 2488-96. PMID 21300764 DOI: 10.1158/0008-5472.Can-10-2820  0.819
2011 Tumanov A, Koroleva E, Fu Y. Lymphotoxin-dependent control of innate immune responses in the gut Inflammatory Bowel Diseases. 17: S11. DOI: 10.1097/00054725-201112002-00031  0.36
2010 Park S, Jiang Z, Mortenson ED, Deng L, Radkevich-Brown O, Yang X, Sattar H, Wang Y, Brown NK, Greene M, Liu Y, Tang J, Wang S, Fu YX. The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity. Cancer Cell. 18: 160-70. PMID 20708157 DOI: 10.1016/J.Ccr.2010.06.014  0.452
2010 Zhu M, Brown NK, Fu YX. Direct and indirect roles of the LTbetaR pathway in central tolerance induction. Trends in Immunology. 31: 325-31. PMID 20675191 DOI: 10.1016/J.It.2010.06.005  0.354
2010 Thompson ED, Enriquez HL, Fu YX, Engelhard VH. Tumor masses support naive T cell infiltration, activation, and differentiation into effectors. The Journal of Experimental Medicine. 207: 1791-804. PMID 20660615 DOI: 10.1084/Jem.20092454  0.43
2010 Blink SE, Fu YX. IgE regulates T helper cell differentiation through FcgammaRIII mediated dendritic cell cytokine modulation. Cellular Immunology. 264: 54-60. PMID 20494341 DOI: 10.1016/J.Cellimm.2010.04.011  0.82
2010 Kanodia S, Da Silva DM, Karamanukyan T, Bogaert L, Fu YX, Kast WM. Expression of LIGHT/TNFSF14 combined with vaccination against human papillomavirus Type 16 E7 induces significant tumor regression. Cancer Research. 70: 3955-64. PMID 20460520 DOI: 10.1158/0008-5472.Can-09-3773  0.454
2010 Wang Y, Koroleva EP, Kruglov AA, Kuprash DV, Nedospasov SA, Fu YX, Tumanov AV. Lymphotoxin beta receptor signaling in intestinal epithelial cells orchestrates innate immune responses against mucosal bacterial infection. Immunity. 32: 403-13. PMID 20226692 DOI: 10.1016/J.Immuni.2010.02.011  0.428
2010 Zhu M, Fu Y. The complicated role of NF-kappaB in T-cell selection. Cellular & Molecular Immunology. 7: 89-93. PMID 20190822 DOI: 10.1038/Cmi.2009.112  0.409
2010 Wang Y, Zhu M, Yu P, Fu YX. Promoting immune responses by LIGHT in the face of abundant regulatory T cell inhibition. Journal of Immunology (Baltimore, Md. : 1950). 184: 1589-95. PMID 20042587 DOI: 10.4049/jimmunol.0901582  0.384
2010 Chen L, Park S, Tumanov AV, Hau A, Sawada K, Feig C, Turner JR, Fu Y, Romero I, Lengyel E, Peter ME. Abstract LB-341: CD95/FAS promotes tumorigenesis Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-341  0.453
2010 Zheng P, Zhou P, Yu P, Zhu M, Wang L, Fu Y, Liu Y. Abstract 4759: Immune prevention of prostate cancer in TRAMP mice targeting lymphotoxin signaling pathway Cancer Research. 70: 4759-4759. DOI: 10.1158/1538-7445.Am10-4759  0.445
2009 Zhou P, Fang X, McNally BA, Yu P, Zhu M, Fu YX, Wang L, Liu Y, Zheng P. Targeting lymphotoxin-mediated negative selection to prevent prostate cancer in mice with genetic predisposition. Proceedings of the National Academy of Sciences of the United States of America. 106: 17134-9. PMID 19805094 DOI: 10.1073/Pnas.0905707106  0.393
2009 Sun Y, Brown NK, Ruddy MJ, Miller ML, Lee Y, Wang Y, Murphy KM, Pfeffer K, Chen L, Kaye J, Fu YX. B and T lymphocyte attenuator tempers early infection immunity. Journal of Immunology (Baltimore, Md. : 1950). 183: 1946-51. PMID 19587015 DOI: 10.4049/Jimmunol.0801866  0.657
2009 Miller ML, Sun Y, Fu YX. Cutting edge: B and T lymphocyte attenuator signaling on NKT cells inhibits cytokine release and tissue injury in early immune responses. Journal of Immunology (Baltimore, Md. : 1950). 183: 32-6. PMID 19535622 DOI: 10.4049/Jimmunol.0900690  0.677
2009 Wang Y, Zhu M, Miller M, Fu YX. Immunoregulation by tumor necrosis factor superfamily member LIGHT. Immunological Reviews. 229: 232-43. PMID 19426225 DOI: 10.1111/J.1600-065X.2009.00762.X  0.584
2009 Lee Y, Auh SL, Wang Y, Burnette B, Wang Y, Meng Y, Beckett M, Sharma R, Chin R, Tu T, Weichselbaum RR, Fu YX. Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment. Blood. 114: 589-95. PMID 19349616 DOI: 10.1182/Blood-2009-02-206870  0.809
2009 Gräbner R, Lötzer K, Döpping S, Hildner M, Radke D, Beer M, Spanbroek R, Lippert B, Reardon CA, Getz GS, Fu YX, Hehlgans T, Mebius RE, van der Wall M, Kruspe D, et al. Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice. The Journal of Experimental Medicine. 206: 233-48. PMID 19139167 DOI: 10.1084/Jem.20080752  0.417
2009 Zhao J, Yang X, Auh SL, Kim KD, Tang H, Fu YX. Do adaptive immune cells suppress or activate innate immunity? Trends in Immunology. 30: 8-12. PMID 19058755 DOI: 10.1016/J.It.2008.10.003  0.802
2009 Tumanov AV, Koroleva EP, Christiansen PA, Khan MA, Ruddy MJ, Burnette B, Papa S, Franzoso G, Nedospasov SA, Fu YX, Anders RA. T cell-derived lymphotoxin regulates liver regeneration. Gastroenterology. 136: 694-704.e4. PMID 18952083 DOI: 10.1053/J.Gastro.2008.09.015  0.772
2008 Chen Y, Wang X, Di L, Fu G, Chen Y, Bai L, Liu J, Feng X, McDonald JM, Michalek S, He Y, Yu M, Fu YX, Wen R, Wu H, et al. Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis. The Journal of Biological Chemistry. 283: 29593-601. PMID 18728019 DOI: 10.1074/Jbc.M802493200  0.33
2008 Yu P, Fu YX. Targeting tumors with LIGHT to generate metastasis-clearing immunity. Cytokine & Growth Factor Reviews. 19: 285-94. PMID 18508404 DOI: 10.1016/J.Cytogfr.2008.04.004  0.465
2008 Zhao J, Kim KD, Yang X, Auh S, Fu YX, Tang H. Hyper innate responses in neonates lead to increased morbidity and mortality after infection. Proceedings of the National Academy of Sciences of the United States of America. 105: 7528-33. PMID 18490660 DOI: 10.1073/Pnas.0800152105  0.799
2008 Zhang Z, Zhang JY, Wherry EJ, Jin B, Xu B, Zou ZS, Zhang SY, Li BS, Wang HF, Wu H, Lau GK, Fu YX, Wang FS. Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B. Gastroenterology. 134: 1938-49, 1949.e1-3. PMID 18455515 DOI: 10.1053/J.Gastro.2008.03.037  0.374
2008 Zhang B, Zhang Y, Bowerman NA, Schietinger A, Fu YX, Kranz DM, Rowley DA, Schreiber H. Equilibrium between host and cancer caused by effector T cells killing tumor stroma. Cancer Research. 68: 1563-71. PMID 18316622 DOI: 10.1158/0008-5472.Can-07-5324  0.414
2008 De Trez C, Schneider K, Potter K, Droin N, Fulton J, Norris PS, Ha SW, Fu YX, Murphy T, Murphy KM, Pfeffer K, Benedict CA, Ware CF. The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 238-48. PMID 18097025 DOI: 10.4049/Jimmunol.180.1.238  0.399
2008 Schreiber H, Zhang B, Schietinger A, Rowley D, Bowerman N, Kranz D, Weichselbaum R, Fu Y, Meredith S, Schreiber K. Tumor-promoting stroma impregnated by cancer cells is destroyed by specific T cells European Journal of Cancer Supplements. 6: 66. DOI: 10.1016/S1359-6349(08)71428-9  0.375
2007 Zhu M, Chin RK, Tumanov AV, Liu X, Fu YX. Lymphotoxin beta receptor is required for the migration and selection of autoreactive T cells in thymic medulla. Journal of Immunology (Baltimore, Md. : 1950). 179: 8069-75. PMID 18056347 DOI: 10.4049/Jimmunol.179.12.8069  0.629
2007 Li J, Li Y, Yao JY, Jin R, Zhu MZ, Qian XP, Zhang J, Fu YX, Wu L, Zhang Y, Chen WF. Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 18175-80. PMID 17984055 DOI: 10.1073/Pnas.0708884104  0.322
2007 Xu G, Liu D, Okwor I, Wang Y, Korner H, Kung SK, Fu YX, Uzonna JE. LIGHT Is critical for IL-12 production by dendritic cells, optimal CD4+ Th1 cell response, and resistance to Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 179: 6901-9. PMID 17982081 DOI: 10.4049/Jimmunol.179.10.6901  0.434
2007 Xu G, Liu D, Fan Y, Yang X, Korner H, Fu YX, Uzonna JE. Lymphotoxin alpha beta 2 (membrane lymphotoxin) is critically important for resistance to Leishmania major infection in mice. Journal of Immunology (Baltimore, Md. : 1950). 179: 5358-66. PMID 17911622 DOI: 10.4049/Jimmunol.179.8.5358  0.383
2007 Tumanov AV, Christiansen PA, Fu YX. The role of lymphotoxin receptor signaling in diseases. Current Molecular Medicine. 7: 567-78. PMID 17896993 DOI: 10.2174/156652407781695701  0.341
2007 Kim KD, Zhao J, Auh S, Yang X, Du P, Tang H, Fu YX. Adaptive immune cells temper initial innate responses. Nature Medicine. 13: 1248-52. PMID 17891146 DOI: 10.1038/Nm1633  0.842
2007 Yu P, Lee Y, Wang Y, Liu X, Auh S, Gajewski TF, Schreiber H, You Z, Kaynor C, Wang X, Fu YX. Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases. Journal of Immunology (Baltimore, Md. : 1950). 179: 1960-8. PMID 17641063 DOI: 10.4049/Jimmunol.179.3.1960  0.805
2007 Schwarz BT, Wang F, Shen L, Clayburgh DR, Su L, Wang Y, Fu YX, Turner JR. LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. Gastroenterology. 132: 2383-94. PMID 17570213 DOI: 10.1053/J.Gastro.2007.02.052  0.357
2007 Lo JC, Wang Y, Tumanov AV, Bamji M, Yao Z, Reardon CA, Getz GS, Fu YX. Lymphotoxin beta receptor-dependent control of lipid homeostasis. Science (New York, N.Y.). 316: 285-8. PMID 17431181 DOI: 10.1126/Science.1137221  0.594
2007 Yang Y, Xiu F, Cai Z, Wang J, Wang Q, Fu Y, Cao X. Increased induction of antitumor response by exosomes derived from interleukin-2 gene-modified tumor cells. Journal of Cancer Research and Clinical Oncology. 133: 389-99. PMID 17219198 DOI: 10.1007/S00432-006-0184-7  0.368
2007 Zhang B, Bowerman NA, Salama JK, Schmidt H, Spiotto MT, Schietinger A, Yu P, Fu YX, Weichselbaum RR, Rowley DA, Kranz DM, Schreiber H. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. The Journal of Experimental Medicine. 204: 49-55. PMID 17210731 DOI: 10.1084/Jem.20062056  0.368
2007 Krieg C, Boyman O, Fu YX, Kaye J. B and T lymphocyte attenuator regulates CD8+ T cell-intrinsic homeostasis and memory cell generation. Nature Immunology. 8: 162-71. PMID 17206146 DOI: 10.1038/Ni1418  0.468
2007 Sharma RR, Lee Y, Knab B, Posner M, Fu Y, Weichselbaum R. Immunotherapy with Ad-LIGHT enhances radiation induced tumor cell death Journal of the American College of Surgeons. 205: S87-S88. DOI: 10.1016/J.Jamcollsurg.2007.06.218  0.373
2006 Zhu M, Chin RK, Christiansen PA, Lo JC, Liu X, Ware C, Siebenlist U, Fu YX. NF-kappaB2 is required for the establishment of central tolerance through an Aire-dependent pathway. The Journal of Clinical Investigation. 116: 2964-71. PMID 17039258 DOI: 10.1172/Jci28326  0.73
2006 Dai S, Zhou X, Wang B, Wang Q, Fu Y, Chen T, Wan T, Yu Y, Cao X. Enhanced induction of dendritic cell maturation and HLA-A*0201-restricted CEA-specific CD8(+) CTL response by exosomes derived from IL-18 gene-modified CEA-positive tumor cells. Journal of Molecular Medicine (Berlin, Germany). 84: 1067-76. PMID 17016692 DOI: 10.1007/S00109-006-0102-0  0.393
2006 Marinkovic T, Garin A, Yokota Y, Fu YX, Ruddle NH, Furtado GC, Lira SA. Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid. The Journal of Clinical Investigation. 116: 2622-32. PMID 16998590 DOI: 10.1172/Jci28993  0.39
2006 Lee Y, Chin RK, Christiansen P, Sun Y, Tumanov AV, Wang J, Chervonsky AV, Fu YX. Recruitment and activation of naive T cells in the islets by lymphotoxin beta receptor-dependent tertiary lymphoid structure. Immunity. 25: 499-509. PMID 16934497 DOI: 10.1016/J.Immuni.2006.06.016  0.599
2006 Sun Y, Blink SE, Liu W, Lee Y, Chen B, Solway J, Weinstock J, Chen L, Fu YX. Inhibition of Th2-mediated allergic airway inflammatory disease by CD137 costimulation. Journal of Immunology (Baltimore, Md. : 1950). 177: 814-21. PMID 16818735 DOI: 10.4049/Jimmunol.177.2.814  0.822
2006 Chin RK, Zhu M, Christiansen PA, Liu W, Ware C, Peltonen L, Zhang X, Guo L, Han S, Zheng B, Fu YX. Lymphotoxin pathway-directed, autoimmune regulator-independent central tolerance to arthritogenic collagen. Journal of Immunology (Baltimore, Md. : 1950). 177: 290-7. PMID 16785524 DOI: 10.4049/Jimmunol.177.1.290  0.607
2006 Kim HK, Guan H, Zu G, Li H, Wu L, Feng X, Elmets C, Fu Y, Xu H. High-level expression of B7-H1 molecules by dendritic cells suppresses the function of activated T cells and desensitizes allergen-primed animals. Journal of Leukocyte Biology. 79: 686-95. PMID 16461745 DOI: 10.1189/Jlb.0805436  0.444
2006 Yu P, Rowley DA, Fu YX, Schreiber H. The role of stroma in immune recognition and destruction of well-established solid tumors. Current Opinion in Immunology. 18: 226-31. PMID 16459066 DOI: 10.1016/J.Coi.2006.01.004  0.426
2006 Yu P, Fu YX. Tumor-infiltrating T lymphocytes: friends or foes? Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 231-45. PMID 16446705 DOI: 10.1038/labinvest.3700389  0.42
2006 Wang YG, Kim KD, Wang J, Yu P, Fu YX. Stimulating lymphotoxin beta receptor on the dendritic cells is critical for their homeostasis and expansion. Journal of Immunology (Baltimore, Md. : 1950). 175: 6997-7002. PMID 16272360 DOI: 10.4049/jimmunol.175.10.6997  0.35
2006 Fan Z, Yu P, Wang Y, Wang Y, Fu ML, Liu W, Sun Y, Fu YX. NK-cell activation by LIGHT triggers tumor-specific CD8+ T-cell immunity to reject established tumors. Blood. 107: 1342-51. PMID 16223768 DOI: 10.1182/Blood-2005-08-3485  0.519
2006 Lo JC, Basak S, James ES, Quiambo RS, Kinsella MC, Alegre ML, Weih F, Franzoso G, Hoffmann A, Fu YX. Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues. Blood. 107: 1048-55. PMID 16195333 DOI: 10.1182/Blood-2005-06-2452  0.533
2005 Han S, Zhang X, Marinova E, Ozen Z, Bheekha-Escura R, Guo L, Wansley D, Booth G, Fu YX, Zheng B. Blockade of lymphotoxin pathway exacerbates autoimmune arthritis by enhancing the Th1 response. Arthritis and Rheumatism. 52: 3202-9. PMID 16200624 DOI: 10.1002/Art.21341  0.31
2005 Wu L, Estrada O, Zaborina O, Bains M, Shen L, Kohler JE, Patel N, Musch MW, Chang EB, Fu YX, Jacobs MA, Nishimura MI, Hancock RE, Turner JR, Alverdy JC. Recognition of host immune activation by Pseudomonas aeruginosa. Science (New York, N.Y.). 309: 774-7. PMID 16051797 DOI: 10.1126/Science.1112422  0.33
2005 Anders RA, Subudhi SK, Wang J, Pfeffer K, Fu YX. Contribution of the lymphotoxin beta receptor to liver regeneration. Journal of Immunology (Baltimore, Md. : 1950). 175: 1295-300. PMID 16002734 DOI: 10.4049/Jimmunol.175.2.1295  0.608
2005 Sun Y, Blink SE, Chen JH, Fu YX. Regulation of follicular dendritic cell networks by activated T cells: the role of CD137 signaling. Journal of Immunology (Baltimore, Md. : 1950). 175: 884-90. PMID 16002686 DOI: 10.4049/Jimmunol.175.2.884  0.83
2005 Wang J, Anders RA, Wang Y, Turner JR, Abraham C, Pfeffer K, Fu YX. The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease. Journal of Immunology (Baltimore, Md. : 1950). 174: 8173-82. PMID 15944326 DOI: 10.4049/Jimmunol.174.12.8173  0.307
2005 Huber C, Thielen C, Seeger H, Schwarz P, Montrasio F, Wilson MR, Heinen E, Fu YX, Miele G, Aguzzi A. Lymphotoxin-beta receptor-dependent genes in lymph node and follicular dendritic cell transcriptomes. Journal of Immunology (Baltimore, Md. : 1950). 174: 5526-36. PMID 15843551 DOI: 10.4049/Jimmunol.174.9.5526  0.338
2005 Wang J, Fu YX. Tumor necrosis factor family members and inflammatory bowel disease. Immunological Reviews. 204: 144-55. PMID 15790356 DOI: 10.1111/J.0105-2896.2005.00218.X  0.337
2005 Yu P, Lee Y, Liu W, Krausz T, Chong A, Schreiber H, Fu YX. Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors. The Journal of Experimental Medicine. 201: 779-91. PMID 15753211 DOI: 10.1084/Jem.20041684  0.496
2005 Wang Y, Subudhi SK, Anders RA, Lo J, Sun Y, Blink S, Wang Y, Wang J, Liu X, Mink K, Degrandi D, Pfeffer K, Fu YX. The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses. The Journal of Clinical Investigation. 115: 711-7. PMID 15696194 DOI: 10.1172/JCI22982  0.829
2005 Shao H, Fu Y, Liao T, Peng Y, Chen L, Kaplan HJ, Sun D. Anti-CD137 mAb treatment inhibits experimental autoimmune uveitis by limiting expansion and increasing apoptotic death of uveitogenic T cells. Investigative Ophthalmology & Visual Science. 46: 596-603. PMID 15671287 DOI: 10.1167/Iovs.04-0835  0.466
2005 Subudhi SK, Alegre ML, Fu YX. The balance of immune responses: costimulation verse coinhibition. Journal of Molecular Medicine (Berlin, Germany). 83: 193-202. PMID 15630593 DOI: 10.1007/S00109-004-0617-1  0.626
2005 Wang J, Fu YX. The role of LIGHT in T cell-mediated immunity. Immunologic Research. 30: 201-14. PMID 15477661 DOI: 10.1385/Ir:30:2:201  0.456
2004 Baron BW, Anastasi J, Montag A, Huo D, Baron RM, Karrison T, Thirman MJ, Subudhi SK, Chin RK, Felsher DW, Fu YX, McKeithan TW, Baron JM. The human BCL6 transgene promotes the development of lymphomas in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 101: 14198-203. PMID 15375218 DOI: 10.1073/Pnas.0406138101  0.734
2004 Lian RH, Chin RK, Nemeth HE, Libby SL, Fu YX, Kumar V. A role for lymphotoxin in the acquisition of Ly49 receptors during NK cell development. European Journal of Immunology. 34: 2699-707. PMID 15368286 DOI: 10.1002/Eji.200425394  0.624
2004 Subudhi SK, Zhou P, Yerian LM, Chin RK, Lo JC, Anders RA, Sun Y, Chen L, Wang Y, Alegre ML, Fu YX. Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection. The Journal of Clinical Investigation. 113: 694-700. PMID 14991067 DOI: 10.1172/Jci19210  0.794
2004 Wu Q, Fu YX, Sontheimer RD. Blockade of lymphotoxin signaling inhibits the clinical expression of murine graft-versus-host skin disease. Journal of Immunology (Baltimore, Md. : 1950). 172: 1630-6. PMID 14734744 DOI: 10.4049/Jimmunol.172.3.1630  0.35
2004 Yu P, Lee Y, Liu W, Chin RK, Wang J, Wang Y, Schietinger A, Philip M, Schreiber H, Fu YX. Priming of naive T cells inside tumors leads to eradication of established tumors. Nature Immunology. 5: 141-9. PMID 14704792 DOI: 10.1038/Ni1029  0.673
2004 Chin R, Wang J, Fu YX. Lymphoid microenvironment in the gut for immunoglobulin A and inflammation. Immunological Reviews. 195: 190-201. PMID 12969319 DOI: 10.1034/J.1600-065X.2003.00066.X  0.637
2003 Kang HS, Blink SE, Chin RK, Lee Y, Kim O, Weinstock J, Waldschmidt T, Conrad D, Chen B, Solway J, Sperling AI, Fu YX. Lymphotoxin is required for maintaining physiological levels of serum IgE that minimizes Th1-mediated airway inflammation. The Journal of Experimental Medicine. 198: 1643-52. PMID 14638845 DOI: 10.1084/Jem.20021784  0.788
2003 Spiotto MT, Fu YX, Schreiber H. Tumor immunity meets autoimmunity: antigen levels and dendritic cell maturation. Current Opinion in Immunology. 15: 725-30. PMID 14630209 DOI: 10.1016/J.Coi.2003.09.018  0.389
2003 Lo JC, Chin RK, Lee Y, Kang HS, Wang Y, Weinstock JV, Banks T, Ware CF, Franzoso G, Fu YX. Differential regulation of CCL21 in lymphoid/nonlymphoid tissues for effectively attracting T cells to peripheral tissues. The Journal of Clinical Investigation. 112: 1495-505. PMID 14617751 DOI: 10.1172/Jci19188  0.746
2003 Sun Y, Subudhi SK, Fu YX. Co-stimulation agonists as a new immunotherapy for autoimmune diseases. Trends in Molecular Medicine. 9: 483-9. PMID 14604826 DOI: 10.1016/J.Molmed.2003.09.011  0.669
2003 Prinz M, Heikenwalder M, Junt T, Schwarz P, Glatzel M, Heppner FL, Fu YX, Lipp M, Aguzzi A. Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature. 425: 957-62. PMID 14562059 DOI: 10.1038/Nature02072  0.342
2003 Mullins DW, Sheasley SL, Ream RM, Bullock TN, Fu YX, Engelhard VH. Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control. The Journal of Experimental Medicine. 198: 1023-34. PMID 14530375 DOI: 10.1084/Jem.20021348  0.488
2003 Chin RK, Lo JC, Kim O, Blink SE, Christiansen PA, Peterson P, Wang Y, Ware C, Fu YX. Lymphotoxin pathway directs thymic Aire expression. Nature Immunology. 4: 1121-7. PMID 14517552 DOI: 10.1038/Ni982  0.777
2003 Liu X, Gao JX, Wen J, Yin L, Li O, Zuo T, Gajewski TF, Fu YX, Zheng P, Liu Y. B7DC/PDL2 promotes tumor immunity by a PD-1-independent mechanism. The Journal of Experimental Medicine. 197: 1721-30. PMID 12810690 DOI: 10.1084/jem.20022089  0.352
2003 Shao H, Fu Y, Song L, Sun S, Kaplan HJ, Sun D. Lymphotoxin beta receptor-Ig fusion protein treatment blocks actively induced, but not adoptively transferred, uveitis in Lewis rats. European Journal of Immunology. 33: 1736-43. PMID 12778492 DOI: 10.1002/Eji.200323745  0.352
2003 Yu P, Spiotto MT, Lee Y, Schreiber H, Fu YX. Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells. The Journal of Experimental Medicine. 197: 985-95. PMID 12695490 DOI: 10.1084/Jem.20021804  0.416
2003 Wang J, Fu YX. LIGHT (a cellular ligand for herpes virus entry mediator and lymphotoxin receptor)-mediated thymocyte deletion is dependent on the interaction between TCR and MHC/self-peptide. Journal of Immunology (Baltimore, Md. : 1950). 170: 3986-93. PMID 12682226 DOI: 10.4049/Jimmunol.170.8.3986  0.339
2003 Zhou P, Hwang KW, Palucki D, Kim O, Newell KA, Fu YX, Alegre ML. Secondary lymphoid organs are important but not absolutely required for allograft responses. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 259-66. PMID 12614279 DOI: 10.1034/J.1600-6143.2003.00067.X  0.355
2002 Spiotto MT, Yu P, Rowley DA, Nishimura MI, Meredith SC, Gajewski TF, Fu YX, Schreiber H. Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity. 17: 737-47. PMID 12479820 DOI: 10.1016/S1074-7613(02)00480-6  0.35
2002 Sun Y, Chen HM, Subudhi SK, Chen J, Koka R, Chen L, Fu YX. Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease. Nature Medicine. 8: 1405-13. PMID 12426559 DOI: 10.1038/Nm1202-796  0.664
2002 Fu YX, Storb U. Immunology. Autoreactive B cells migrate into T cell territory. Science (New York, N.Y.). 297: 2006-8. PMID 12242429 DOI: 10.1126/Science.1077011  0.407
2002 Wang J, Foster A, Chin R, Yu P, Sun Y, Wang Y, Pfeffer K, Fu YX. The complementation of lymphotoxin deficiency with LIGHT, a newly discovered TNF family member, for the restoration of secondary lymphoid structure and function. European Journal of Immunology. 32: 1969-79. PMID 12115617 DOI: 10.1002/1521-4141(200207)32:7<1969::Aid-Immu1969>3.0.Co;2-M  0.658
2002 Kang HS, Chin RK, Wang Y, Yu P, Wang J, Newell KA, Fu YX. Signaling via LTbetaR on the lamina propria stromal cells of the gut is required for IgA production. Nature Immunology. 3: 576-82. PMID 12006975 DOI: 10.1038/Ni795  0.623
2002 Yu P, Wang Y, Chin RK, Martinez-Pomares L, Gordon S, Kosco-Vibois MH, Cyster J, Fu YX. B cells control the migration of a subset of dendritic cells into B cell follicles via CXC chemokine ligand 13 in a lymphotoxin-dependent fashion. Journal of Immunology (Baltimore, Md. : 1950). 168: 5117-23. PMID 11994465 DOI: 10.4049/Jimmunol.168.10.5117  0.655
2002 Tamada K, Tamura H, Flies D, Fu YX, Celis E, Pease LR, Blazar BR, Chen L. Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease. The Journal of Clinical Investigation. 109: 549-57. PMID 11854328 DOI: 10.1172/JCI13604  0.38
2002 Sun Y, Lin X, Chen HM, Wu Q, Subudhi SK, Chen L, Fu YX. Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 168: 1457-65. PMID 11801689 DOI: 10.4049/Jimmunol.168.3.1457  0.704
2001 Wang J, Lo JC, Foster A, Yu P, Chen HM, Wang Y, Tamada K, Chen L, Fu YX. The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT. The Journal of Clinical Investigation. 108: 1771-80. PMID 11748260 DOI: 10.1172/Jci13827  0.665
2001 Wang J, Chun T, Lo JC, Wu Q, Wang Y, Foster A, Roca K, Chen M, Tamada K, Chen L, Wang CR, Fu YX. The critical role of LIGHT, a TNF family member, in T cell development. Journal of Immunology (Baltimore, Md. : 1950). 167: 5099-105. PMID 11673520 DOI: 10.4049/Jimmunol.167.9.5099  0.632
2001 Guo Z, Wang J, Meng L, Wu Q, Kim O, Hart J, He G, Zhou P, Thistlethwaite JR, Alegre ML, Fu YX, Newell KA. Cutting edge: membrane lymphotoxin regulates CD8(+) T cell-mediated intestinal allograft rejection. Journal of Immunology (Baltimore, Md. : 1950). 167: 4796-800. PMID 11673481 DOI: 10.4049/Jimmunol.167.9.4796  0.423
2001 Fu Y, Sies H, Lei XG. Opposite roles of selenium-dependent glutathione peroxidase-1 in superoxide generator diquat- and peroxynitrite-induced apoptosis and signaling. The Journal of Biological Chemistry. 276: 43004-9. PMID 11562367 DOI: 10.1074/Jbc.M106946200  0.334
2001 Zhu G, Flies DB, Tamada K, Sun Y, Rodriguez M, Fu YX, Chen L. Progressive depletion of peripheral B lymphocytes in 4-1BB (CD137) ligand/I-Ealpha)-transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 167: 2671-6. PMID 11509610 DOI: 10.4049/Jimmunol.167.5.2671  0.498
2001 Fu Y, McCormick CC, Roneker C, Lei XG. Lipopolysaccharide and interferon-gamma-induced nitric oxide production and protein oxidation in mouse peritoneal macrophages are affected by glutathione peroxidase-1 gene knockout. Free Radical Biology & Medicine. 31: 450-9. PMID 11498278 DOI: 10.1016/S0891-5849(01)00607-4  0.305
2001 Wu Q, Salomon B, Chen M, Wang Y, Hoffman LM, Bluestone JA, Fu YX. Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor Journal of Experimental Medicine. 193: 1327-1332. PMID 11390440 DOI: 10.1084/Jem.193.11.1327  0.319
2001 Rennert PD, Hochman PS, Flavell RA, Chaplin DD, Jayaraman S, Browning JL, Fu YX. Essential role of lymph nodes in contact hypersensitivity revealed in lymphotoxin-alpha-deficient mice. The Journal of Experimental Medicine. 193: 1227-38. PMID 11390430 DOI: 10.1084/Jem.193.11.1227  0.458
2001 Wu Q, Sun Y, Wang J, Lin X, Wang Y, Pegg LE, Fütterer A, Pfeffer K, Fu Y. Signal Via Lymphotoxin-βR on Bone Marrow Stromal Cells Is Required for an Early Checkpoint of NK Cell Development Journal of Immunology. 166: 1684-1689. PMID 11160211 DOI: 10.4049/Jimmunol.166.3.1684  0.379
2001 Wang Y, Wang J, Sun Y, Wu Q, Fu Y. Complementary effects of TNF and lymphotoxin on the formation of germinal center and follicular dendritic cells. Journal of Immunology. 166: 330-337. PMID 11123309 DOI: 10.4049/Jimmunol.166.1.330  0.408
2001 Fu Y, Porres JM, Lei XG. Comparative impacts of glutathione peroxidase-1 gene knockout on oxidative stress induced by reactive oxygen and nitrogen species in mouse hepatocytes Biochemical Journal. 359: 687-695. DOI: 10.1042/Bj3590687  0.346
2000 Wu X, Jiang N, Fang Y, Xu C, Mao D, Singh J, Fu Y, Molina H. Impaired affinity maturation in Cr2-/- mice is rescued by adjuvants without improvement in germinal center development. Journal of Immunology. 165: 3119-3127. PMID 10975825 DOI: 10.4049/Jimmunol.165.6.3119  0.374
2000 Wang Y, Huang G, Wang J, Molina H, Chaplin DD, Fu YX. Antigen persistence is required for somatic mutation and affinity maturation of immunoglobulin. European Journal of Immunology. 30: 2226-34. PMID 10940914 DOI: 10.1002/1521-4141(2000)30:8<2226::Aid-Immu2226>3.0.Co;2-5  0.386
2000 Tamada K, Shimozaki K, Chapoval AI, Zhu G, Sica G, Flies D, Boone T, Hsu H, Fu YX, Nagata S, Ni J, Chen L. Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway. Nature Medicine. 6: 283-9. PMID 10700230 DOI: 10.1038/73136  0.419
2000 Fu YX, Huang G, Wang Y, Chaplin DD. Lymphotoxin-alpha-dependent spleen microenvironment supports the generation of memory B cells and is required for their subsequent antigen-induced activation. Journal of Immunology (Baltimore, Md. : 1950). 164: 2508-14. PMID 10679088 DOI: 10.4049/Jimmunol.164.5.2508  0.378
1999 Wu Q, Wang Y, Wang J, Hedgeman EO, Browning JL, Fu YX. The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues. The Journal of Experimental Medicine. 190: 629-38. PMID 10477548 DOI: 10.1084/Jem.190.5.629  0.359
1998 Fu YX, Huang G, Wang Y, Chaplin DD. B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion. The Journal of Experimental Medicine. 187: 1009-18. PMID 9529317 DOI: 10.1084/Jem.187.7.1009  0.485
1997 Matsumoto M, Fu YX, Molina H, Huang G, Kim J, Thomas DA, Nahm MH, Chaplin DD. Distinct roles of lymphotoxin α and the type i tumor necrosis factor (TNF) receptor in the establishment of follicular dendritic cells from non- bone marrow-derived cells Journal of Experimental Medicine. 186: 1997-2004. PMID 9396768 DOI: 10.1084/Jem.186.12.1997  0.374
1997 Fu YX, Molina H, Matsumoto M, Huang G, Min J, Chaplin DD. Lymphotoxin-alpha (LTalpha) supports development of splenic follicular structure that is required for IgG responses. The Journal of Experimental Medicine. 185: 2111-20. PMID 9182683 DOI: 10.1084/Jem.185.12.2111  0.469
1997 Fu YX, Huang G, Matsumoto M, Molina H, Chaplin DD. Independent signals regulate development of primary and secondary follicle structure in spleen and mesenteric lymph node. Proceedings of the National Academy of Sciences of the United States of America. 94: 5739-43. PMID 9159143 DOI: 10.1073/Pnas.94.11.5739  0.426
1995 Sotomayor EM, DiNapoli MR, Calderon C, Colsky A, Fu YX, Lopez DM. Decreased macrophage-mediated cytotoxicity in mammary-tumor-bearing mice is related to alteration of nitric-oxide production and/or release International Journal of Cancer. 60: 660-667. PMID 7860141 DOI: 10.1002/Ijc.2910600516  0.432
1993 Fu Y, Cranfill R, Vollmer M, Zee RVD, O'brien RL, Born W. In vivo response of murine gamma delta T cells to a heat shock protein-derived peptide Proceedings of the National Academy of Sciences of the United States of America. 90: 322-326. PMID 8093560 DOI: 10.1073/Pnas.90.1.322  0.435
1992 O'brien RL, Fu YX, Cranfill R, Dallas A, Ellis C, Reardon C, Lang J, Carding SR, Kubo R, Born W. Heat shock protein Hsp60-reactive γδ cells: A large, diversified T-lymphocyte subset with highly focused specificity Proceedings of the National Academy of Sciences of the United States of America. 89: 4348-4352. PMID 1584768 DOI: 10.1073/Pnas.89.10.4348  0.388
1991 Watson GA, Fu YX, Lopez DM. Splenic macrophages from tumor-bearing mice co-expressing MAC-1 and MAC-2 antigens exert immunoregulatory functions via two distinct mechanisms Journal of Leukocyte Biology. 49: 126-138. PMID 1991996 DOI: 10.1002/Jlb.49.2.126  0.541
1991 O'Brien RL, Happ MP, Dallas A, Cranfill R, Hall L, Lang J, Fu YX, Kubo R, Born W. Recognition of a single hsp-60 epitope by an entire subset of γδ T lymphocytes Immunological Reviews. 155-170. PMID 1718844 DOI: 10.1111/J.1600-065X.1991.Tb00827.X  0.413
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