| Year |
Citation |
Score |
| 2022 |
Panayi MC, Boerner T, Jahans-Price T, Huber A, Sprengel R, Gilmour G, Sanderson DJ, Harrison PJ, Walton ME, Bannerman DM. Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience. Molecular Psychiatry. PMID 36460723 DOI: 10.1038/s41380-022-01861-8 |
0.688 |
|
| 2022 |
Harrison PJ, Husain SM, Lee H, Los Angeles A, Colbourne L, Mould A, Hall NAL, Haerty W, Tunbridge EM. CACNA1C (Ca1.2) and other L-type calcium channels in the pathophysiology and treatment of psychiatric disorders: Advances from functional genomics and pharmacoepidemiology. Neuropharmacology. 220: 109262. PMID 36154842 DOI: 10.1016/j.neuropharm.2022.109262 |
0.61 |
|
| 2022 |
Harrison PJ, Mould A, Tunbridge EM. New drug targets in psychiatry: Neurobiological considerations in the genomics era. Neuroscience and Biobehavioral Reviews. 139: 104763. PMID 35787892 DOI: 10.1016/j.neubiorev.2022.104763 |
0.603 |
|
| 2022 |
Martens MA, Dalton N, Scaife J, Harmer CJ, Harrison PJ, Tunbridge EM. Catechol-O-methyltransferase activity does not influence emotional processing in men. Journal of Psychopharmacology (Oxford, England). 2698811221089032. PMID 35443830 DOI: 10.1177/02698811221089032 |
0.573 |
|
| 2021 |
Hong JSW, Atkinson LZ, Al-Juffali N, Awad A, Geddes JR, Tunbridge EM, Harrison PJ, Cipriani A. Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale. Molecular Psychiatry. PMID 34819636 DOI: 10.1038/s41380-021-01386-6 |
0.596 |
|
| 2021 |
De Los Angeles A, Fernando MB, Hall NAL, Brennand KJ, Harrison PJ, Maher BJ, Weinberger DR, Tunbridge EM. Induced Pluripotent Stem Cells in Psychiatry: An Overview and Critical Perspective. Biological Psychiatry. PMID 34176589 DOI: 10.1016/j.biopsych.2021.04.008 |
0.626 |
|
| 2020 |
Taquet M, Smith SM, Prohl AK, Peters JM, Warfield SK, Scherrer B, Harrison PJ. A structural brain network of genetic vulnerability to psychiatric illness. Molecular Psychiatry. PMID 32372008 DOI: 10.1038/S41380-020-0723-7 |
0.321 |
|
| 2020 |
Lee H, Hall N, Wreszinski T, Weinberger D, Harrison P, Haerty W, Tunbridge E. P.121 Characterizing the transcriptional profile of L-type calcium channels (CACNA1S and, CACNA1F) in human brain European Neuropsychopharmacology. 31. DOI: 10.1016/J.Euroneuro.2019.12.022 |
0.604 |
|
| 2020 |
Martens M, Tunbridge E, Harrison P. The Interaction Between COMT Genotype and Tolcapone on Cerebral Perfusion and Resting-State Functional Connectivity Biological Psychiatry. 87: S344-S345. DOI: 10.1016/J.Biopsych.2020.02.884 |
0.604 |
|
| 2020 |
Hall N, Clark MB, Wrzesinski T, Garcia AB, Husain SM, Kleinman JE, Hyde T, Weinberger DR, Harrison PJ, Haerty W, Tunbridge EM. Exploiting the Variability of CACNA1C Splicing to Identify Novel, Brain-Selective Targets for Schizophrenia and Bipolar Disorder Biological Psychiatry. 87: S172-S173. DOI: 10.1016/J.Biopsych.2020.02.455 |
0.692 |
|
| 2019 |
Harrison PJ, Geddes JR, Tunbridge EM. The Emerging Neurobiology of Bipolar Disorder. Focus (American Psychiatric Publishing). 17: 284-293. PMID 32015720 DOI: 10.1176/appi.focus.17309 |
0.589 |
|
| 2019 |
Harrison PJ, Hall N, Mould A, Al-Juffali N, Tunbridge EM. Cellular calcium in bipolar disorder: systematic review and meta-analysis. Molecular Psychiatry. PMID 31801967 DOI: 10.1038/S41380-019-0622-Y |
0.634 |
|
| 2019 |
Clark MB, Wrzesinski T, Garcia AB, Hall NAL, Kleinman JE, Hyde T, Weinberger DR, Harrison PJ, Haerty W, Tunbridge EM. Long-read sequencing reveals the complex splicing profile of the psychiatric risk gene CACNA1C in human brain. Molecular Psychiatry. PMID 31695164 DOI: 10.1038/S41380-019-0583-1 |
0.68 |
|
| 2019 |
Ward J, Tunbridge EM, Sandor C, Lyall LM, Ferguson A, Strawbridge RJ, Lyall DM, Cullen B, Graham N, Johnston KJA, Webber C, Escott-Price V, O'Donovan M, Pell JP, Bailey MES, ... Harrison PJ, et al. Correction: The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function. Molecular Psychiatry. PMID 31363164 DOI: 10.1038/s41380-019-0466-5 |
0.604 |
|
| 2019 |
Tunbridge EM, Narajos M, Harrison CH, Beresford C, Cipriani A, Harrison PJ. Which Dopamine Polymorphisms Are Functional? Systematic Review and Meta-analysis of COMT, DAT, DBH, DDC, DRD1-5, MAOA, MAOB, TH, VMAT1, and VMAT2. Biological Psychiatry. PMID 31303260 DOI: 10.1016/J.Biopsych.2019.05.014 |
0.634 |
|
| 2019 |
Martens MA, Antley A, Freeman D, Slater M, Harrison PJ, Tunbridge EM. It feels real: physiological responses to a stressful virtual reality environment and its impact on working memory. Journal of Psychopharmacology (Oxford, England). 269881119860156. PMID 31294651 DOI: 10.1177/0269881119860156 |
0.6 |
|
| 2019 |
Harrison PJ, Tunbridge EM, Dolphin AC, Hall J. Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal. The British Journal of Psychiatry : the Journal of Mental Science. 1-4. PMID 31230606 DOI: 10.1192/Bjp.2019.157 |
0.617 |
|
| 2019 |
Ward J, Tunbridge EM, Sandor C, Lyall LM, Ferguson A, Strawbridge RJ, Lyall DM, Cullen B, Graham N, Johnston KJA, Webber C, Escott-Price V, O'Donovan M, Pell JP, Bailey MES, ... Harrison PJ, et al. The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function. Molecular Psychiatry. PMID 31168069 DOI: 10.1038/S41380-019-0439-8 |
0.657 |
|
| 2019 |
Atkinson LZ, Colbourne L, Smith A, Harmer CH, Nobre AC, Rendell J, Jones H, Hinds C, Mould A, Tunbridge EM, Cipriani A, Geddes JR, Saunders KEA, Harrison PJ. The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study. Trials. 20: 120. PMID 30755265 DOI: 10.1186/S13063-019-3175-0 |
0.62 |
|
| 2019 |
Ward J, Tunbridge E, Sandor C, Webber C, Lyall L, Ferguson A, Strawbridge R, Lyall D, Cullen B, Graham N, Johnston K, Bail M, Pell J, Harrison P, Smith D. F80Genome-Wide Association Of 45 Loci With Mood Instability In 363,705 Uk Biobank Participants: Genetic Correlation With Multiple Psychiatric Phenotypes And Association With Nervous System Function European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.08.160 |
0.619 |
|
| 2019 |
Strawbridge R, Ward J, Cullen B, Tunbridge E, Hartz S, Bierut L, Bailey M, Graham N, Ferguson A, Lyall D, Pidgeon L, O'Donovan M, Escott-Price V, Harrison P, Smith D. Genome-Wide Analysis Of Risk-Taking Behaviour In 116 255 Individuals From The Uk Biobank Cohort And Cross-Disorder Genetic Correlations European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.356 |
0.643 |
|
| 2018 |
Deakin IH, Godlewska BR, Walker MA, Huang GJ, Schwab MH, Nave KA, Law AJ, Harrison PJ. Altered hippocampal gene expression and structure in transgenic mice overexpressing neuregulin 1 (Nrg1) type I. Translational Psychiatry. 8: 229. PMID 30348978 DOI: 10.1038/S41398-018-0288-2 |
0.605 |
|
| 2018 |
Strawbridge RJ, Ward J, Lyall LM, Tunbridge EM, Cullen B, Graham N, Ferguson A, Johnston KJA, Lyall DM, Mackay D, Cavanagh J, Howard DM, Adams MJ, Deary I, Escott-Price V, ... ... Harrison PJ, et al. Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression. Translational Psychiatry. 8: 178. PMID 30181555 DOI: 10.1038/s41398-018-0236-1 |
0.65 |
|
| 2018 |
Kano SI, Hodgkinson CA, Jones-Brando L, Eastwood S, Ishizuka K, Niwa M, Choi EY, Chang DJ, Chen Y, Velivela SD, Leister F, Wood J, Chowdari K, Ducci F, Caycedo DA, ... ... Harrison PJ, et al. Host-parasite interaction associated with major mental illness. Molecular Psychiatry. PMID 30127472 DOI: 10.1038/S41380-018-0217-Z |
0.319 |
|
| 2018 |
Harrison PJ, Colbourne L, Harrison CH. The neuropathology of bipolar disorder: systematic review and meta-analysis. Molecular Psychiatry. PMID 30127470 DOI: 10.1038/S41380-018-0213-3 |
0.303 |
|
| 2018 |
Strawbridge RJ, Ward J, Cullen B, Tunbridge EM, Hartz S, Bierut L, Horton A, Bailey MES, Graham N, Ferguson A, Lyall DM, Mackay D, Pidgeon LM, Cavanagh J, Pell JP, ... ... Harrison PJ, et al. Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort. Translational Psychiatry. 8: 39. PMID 29391395 DOI: 10.1038/S41398-017-0079-1 |
0.635 |
|
| 2017 |
Harrison PJ, Geddes JR, Tunbridge EM. The Emerging Neurobiology of Bipolar Disorder. Trends in Neurosciences. PMID 29169634 DOI: 10.1016/J.Tins.2017.10.006 |
0.636 |
|
| 2017 |
Tunbridge EM, Attenburrow MJ, Gardiner A, Rendell JM, Hinds C, Goodwin GM, Harrison PJ, Geddes JR. Biochemical and genetic predictors and correlates of response to lamotrigine and folic acid in bipolar depression: Analysis of the CEQUEL clinical trial. Bipolar Disorders. 19: 477-486. PMID 28833962 DOI: 10.1111/Bdi.12531 |
0.604 |
|
| 2017 |
García-Bea A, Bermudez I, Harrison PJ, Lane TA. A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding. Journal of Psychopharmacology (Oxford, England). 269881117715597. PMID 28655286 DOI: 10.1177/0269881117715597 |
0.336 |
|
| 2017 |
Harrison PJ. ZNF804A: Insights From the First Genome-wide Significant Schizophrenia Gene. Biological Psychiatry. 82: 6-7. PMID 28619252 DOI: 10.1016/J.Biopsych.2017.03.024 |
0.306 |
|
| 2017 |
Martens M, Tunbridge E, Harrison P. Physiological and psychological effects of the Montreal Imaging Stress Task European Neuropsychopharmacology. 27. DOI: 10.1016/S0924-977X(17)30136-0 |
0.585 |
|
| 2016 |
Barkus C, Korn C, Stumpenhorst K, Laatikainen LM, Ballard D, Lee S, Sharp T, Harrison PJ, Bannerman DM, Weinberger DR, Chen J, Tunbridge EM. Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly-Specific, Novel Mouse Model of Altered COMT Activity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27388330 DOI: 10.1038/Npp.2016.119 |
0.774 |
|
| 2016 |
Cipriani A, Saunders K, Attenburrow MJ, Stefaniak J, Panchal P, Stockton S, Lane TA, Tunbridge EM, Geddes JR, Harrison PJ. A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development. Molecular Psychiatry. PMID 27240535 DOI: 10.1038/Mp.2016.86 |
0.644 |
|
| 2016 |
García-Bea A, Walker MA, Hyde TM, Kleinman JE, Harrison PJ, Lane TA. Metabotropic glutamate receptor 3 (mGlu3; mGluR3; GRM3) in schizophrenia: Antibody characterisation and a semi-quantitative western blot study. Schizophrenia Research. PMID 27130562 DOI: 10.1016/J.Schres.2016.04.015 |
0.338 |
|
| 2016 |
Harrison PJ, Cipriani A, Harmer CJ, Nobre AC, Saunders K, Goodwin GM, Geddes JR. Innovative approaches to bipolar disorder and its treatment. Annals of the New York Academy of Sciences. 1366: 76-89. PMID 27111134 DOI: 10.1111/Nyas.13048 |
0.307 |
|
| 2016 |
Bygrave AM, Masiulis S, Nicholson E, Berkemann M, Barkus C, Sprengel R, Harrison PJ, Kullmann DM, Bannerman DM, Kätzel D. Knockout of NMDA-receptors from parvalbumin interneurons sensitizes to schizophrenia-related deficits induced by MK-801. Translational Psychiatry. 6: e778. PMID 27070406 DOI: 10.1038/Tp.2016.44 |
0.33 |
|
| 2016 |
Harrison PJ. Neuropathological studies of bipolar disorder. Acta Neuropsychiatrica. 12: 96-8. PMID 26975261 DOI: 10.1017/S0924270800035493 |
0.326 |
|
| 2016 |
Pritchett D, Taylor AM, Barkus C, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Peirson SN, Bannerman DM. Searching for cognitive enhancement in the Morris watermaze: Better and worse performance in D-amino acid oxidase knockout (Dao(-/-) ) mice. The European Journal of Neuroscience. PMID 26833794 DOI: 10.1111/Ejn.13192 |
0.481 |
|
| 2015 |
Geddes JR, Gardiner A, Rendell J, Voysey M, Tunbridge E, Hinds C, Yu LM, Hainsworth J, Attenburrow MJ, Simon J, Goodwin GM, Harrison PJ. Comparative evaluation of quetiapine plus lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in bipolar depression (CEQUEL): a 2 × 2 factorial randomised trial. The Lancet. Psychiatry. PMID 26687300 DOI: 10.1016/S2215-0366(15)00450-2 |
0.603 |
|
| 2015 |
Tunbridge EM, Dunn G, Murray RM, Evans N, Lister R, Stumpenhorst K, Harrison PJ, Morrison PD, Freeman D. Genetic moderation of the effects of cannabis: Catechol-O-methyltransferase (COMT) affects the impact of Δ9-tetrahydrocannabinol (THC) on working memory performance but not on the occurrence of psychotic experiences. Journal of Psychopharmacology (Oxford, England). PMID 26464454 DOI: 10.1177/0269881115609073 |
0.631 |
|
| 2015 |
Harrison PJ. Molecular neurobiological clues to the pathogenesis of bipolar disorder. Current Opinion in Neurobiology. 36: 1-6. PMID 26210959 DOI: 10.1016/J.Conb.2015.07.002 |
0.329 |
|
| 2015 |
Pritchett D, Hasan S, Tam SK, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Bannerman DM, Peirson SN. d-amino acid oxidase knockout (Dao(-/-) ) mice show enhanced short-term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption. The European Journal of Neuroscience. 41: 1167-79. PMID 25816902 DOI: 10.1111/Ejn.12880 |
0.473 |
|
| 2015 |
Cousijn H, Tunbridge EM, Rolinski M, Wallis G, Colclough GL, Woolrich MW, Nobre AC, Harrison PJ. Modulation of hippocampal theta and hippocampal-prefrontal cortex function by a schizophrenia risk gene. Human Brain Mapping. 36: 2387-95. PMID 25757652 DOI: 10.1002/Hbm.22778 |
0.655 |
|
| 2015 |
Harrison PJ. GABA circuitry, cells and molecular regulation in schizophrenia: Life in the graveyard. Schizophrenia Research. PMID 25694185 DOI: 10.1016/J.Schres.2015.02.003 |
0.306 |
|
| 2015 |
Harrison PJ. Recent genetic findings in schizophrenia and their therapeutic relevance. Journal of Psychopharmacology (Oxford, England). 29: 85-96. PMID 25315827 DOI: 10.1177/0269881114553647 |
0.355 |
|
| 2015 |
Freeman D, Dunn G, Murray RM, Evans N, Lister R, Antley A, Slater M, Godlewska B, Cornish R, Williams J, Di Simplicio M, Igoumenou A, Brenneisen R, Tunbridge EM, Harrison PJ, et al. How cannabis causes paranoia: using the intravenous administration of ∆9-tetrahydrocannabinol (THC) to identify key cognitive mechanisms leading to paranoia. Schizophrenia Bulletin. 41: 391-9. PMID 25031222 DOI: 10.1093/Schbul/Sbu098 |
0.622 |
|
| 2014 |
Barkus C, Sanderson DJ, Rawlins JN, Walton ME, Harrison PJ, Bannerman DM. What causes aberrant salience in schizophrenia? A role for impaired short-term habituation and the GRIA1 (GluA1) AMPA receptor subunit. Molecular Psychiatry. 19: 1060-70. PMID 25224260 DOI: 10.1038/Mp.2014.91 |
0.353 |
|
| 2014 |
Cousijn H, Eissing M, Fernández G, Fisher SE, Franke B, Zwiers M, Harrison PJ, Arias-Vásquez A. No effect of schizophrenia risk genes MIR137, TCF4, and ZNF804A on macroscopic brain structure. Schizophrenia Research. 159: 329-32. PMID 25217366 DOI: 10.1016/J.Schres.2014.08.007 |
0.321 |
|
| 2014 |
Tao R, Cousijn H, Jaffe AE, Burnet PW, Edwards F, Eastwood SL, Shin JH, Lane TA, Walker MA, Maher BJ, Weinberger DR, Harrison PJ, Hyde TM, Kleinman JE. Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706. Jama Psychiatry. 71: 1112-20. PMID 25162540 DOI: 10.1001/Jamapsychiatry.2014.1079 |
0.472 |
|
| 2014 |
Schweimer JV, Coullon GS, Betts JF, Burnet PW, Engle SJ, Brandon NJ, Harrison PJ, Sharp T. Increased burst-firing of ventral tegmental area dopaminergic neurons in D-amino acid oxidase knockout mice in vivo. The European Journal of Neuroscience. 40: 2999-3009. PMID 25040393 DOI: 10.1111/Ejn.12667 |
0.778 |
|
| 2014 |
Betts JF, Schweimer JV, Burnham KE, Burnet PW, Sharp T, Harrison PJ. D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine. Frontiers in Synaptic Neuroscience. 6: 11. PMID 24822045 DOI: 10.3389/Fnsyn.2014.00011 |
0.788 |
|
| 2014 |
Carter CS, Bullmore ET, Harrison P. Is there a flame in the brain in psychosis? Biological Psychiatry. 75: 258-9. PMID 24439553 DOI: 10.1016/J.Biopsych.2013.10.023 |
0.349 |
|
| 2013 |
Lane TA, Boerner T, Bannerman DM, Kew JN, Tunbridge EM, Sharp T, Harrison PJ. Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice. Bmc Neuroscience. 14: 102. PMID 24053122 DOI: 10.1186/1471-2202-14-102 |
0.699 |
|
| 2013 |
Laatikainen LM, Sharp T, Harrison PJ, Tunbridge EM. Sexually dimorphic effects of catechol-O-methyltransferase (COMT) inhibition on dopamine metabolism in multiple brain regions. Plos One. 8: e61839. PMID 23613951 DOI: 10.1371/Journal.Pone.0061839 |
0.692 |
|
| 2013 |
Tunbridge EM, Farrell SM, Harrison PJ, Mackay CE. Catechol-O-methyltransferase (COMT) influences the connectivity of the prefrontal cortex at rest. Neuroimage. 68: 49-54. PMID 23228511 DOI: 10.1016/J.Neuroimage.2012.11.059 |
0.642 |
|
| 2012 |
Laatikainen LM, Sharp T, Bannerman DM, Harrison PJ, Tunbridge EM. Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition. Journal of Psychopharmacology (Oxford, England). 26: 1561-8. PMID 22815336 DOI: 10.1177/0269881112454228 |
0.694 |
|
| 2012 |
Law AJ, Wang Y, Sei Y, O'Donnell P, Piantadosi P, Papaleo F, Straub RE, Huang W, Thomas CJ, Vakkalanka R, Besterman AD, Lipska BK, Hyde TM, Harrison PJ, Kleinman JE, et al. Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy. Proceedings of the National Academy of Sciences of the United States of America. 109: 12165-70. PMID 22689948 DOI: 10.1073/Pnas.1206118109 |
0.674 |
|
| 2012 |
Matthews PR, Eastwood SL, Harrison PJ. Reduced myelin basic protein and actin-related gene expression in visual cortex in schizophrenia. Plos One. 7: e38211. PMID 22675524 DOI: 10.1371/Journal.Pone.0038211 |
0.357 |
|
| 2012 |
Pritchett D, Wulff K, Oliver PL, Bannerman DM, Davies KE, Harrison PJ, Peirson SN, Foster RG. Evaluating the links between schizophrenia and sleep and circadian rhythm disruption. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 1061-75. PMID 22569850 DOI: 10.1007/S00702-012-0817-8 |
0.328 |
|
| 2012 |
Tunbridge EM, Huber A, Farrell SM, Stumpenhorst K, Harrison PJ, Walton ME. The role of catechol-O-methyltransferase in reward processing and addiction. Cns & Neurological Disorders Drug Targets. 11: 306-23. PMID 22483300 DOI: 10.2174/187152712800672409 |
0.777 |
|
| 2012 |
Farrell SM, Tunbridge EM, Braeutigam S, Harrison PJ. COMT Val(158)Met genotype determines the direction of cognitive effects produced by catechol-O-methyltransferase inhibition. Biological Psychiatry. 71: 538-44. PMID 22364739 DOI: 10.1016/J.Biopsych.2011.12.023 |
0.643 |
|
| 2012 |
Cousijn H, Rijpkema M, Harteveld A, Harrison PJ, Fernández G, Franke B, Arias-Vásquez A. Schizophrenia risk gene ZNF804A does not influence macroscopic brain structure: an MRI study in 892 volunteers. Molecular Psychiatry. 17: 1155-7. PMID 22270476 DOI: 10.1038/Mp.2011.181 |
0.315 |
|
| 2012 |
Matthews PR, Harrison PJ. A morphometric, immunohistochemical, and in situ hybridization study of the dorsal raphe nucleus in major depression, bipolar disorder, schizophrenia, and suicide. Journal of Affective Disorders. 137: 125-34. PMID 22129767 DOI: 10.1016/J.Jad.2011.10.043 |
0.314 |
|
| 2012 |
Deakin IH, Nissen W, Law AJ, Lane T, Kanso R, Schwab MH, Nave KA, Lamsa KP, Paulsen O, Bannerman DM, Harrison PJ. Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation. Cerebral Cortex (New York, N.Y. : 1991). 22: 1520-9. PMID 21878485 DOI: 10.1093/Cercor/Bhr223 |
0.598 |
|
| 2012 |
Harrison PJ, Pritchett D, Stumpenhorst K, Betts JF, Nissen W, Schweimer J, Lane T, Burnet PW, Lamsa KP, Sharp T, Bannerman DM, Tunbridge EM. Genetic mouse models relevant to schizophrenia: taking stock and looking forward. Neuropharmacology. 62: 1164-7. PMID 21864547 DOI: 10.1016/J.Neuropharm.2011.08.009 |
0.784 |
|
| 2011 |
Tunbridge EM, Harrison PJ. Importance of the COMT gene for sex differences in brain function and predisposition to psychiatric disorders. Current Topics in Behavioral Neurosciences. 8: 119-40. PMID 21769726 DOI: 10.1007/7854_2010_97 |
0.65 |
|
| 2011 |
Kleinman JE, Law AJ, Lipska BK, Hyde TM, Ellis JK, Harrison PJ, Weinberger DR. Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains. Biological Psychiatry. 69: 140-5. PMID 21183009 DOI: 10.1016/J.Biopsych.2010.10.032 |
0.679 |
|
| 2011 |
Harrison PJ. Using our brains: the findings, flaws, and future of postmortem studies of psychiatric disorders. Biological Psychiatry. 69: 102-3. PMID 21183008 DOI: 10.1016/J.Biopsych.2010.09.008 |
0.315 |
|
| 2011 |
Tunbridge EM, Eastwood SL, Harrison PJ. Changed relative to what? Housekeeping genes and normalization strategies in human brain gene expression studies. Biological Psychiatry. 69: 173-9. PMID 20673871 DOI: 10.1016/J.Biopsych.2010.05.023 |
0.647 |
|
| 2011 |
Harrison PJ, Lewis DA, Kleinman JE. Neuropathology of Schizophrenia Schizophrenia: Third Edition. 372-392. DOI: 10.1383/Psyt.2005.4.10.18 |
0.351 |
|
| 2011 |
Laatikainen L, Sharp T, Harrison P, Tunbridge E. P.4.002 Catechol-o-methyltransferase (COMT) influences dopamine metabolism outside of the prefrontal cortex European Neuropsychopharmacology. 21: S79-S80. DOI: 10.1016/S0924-977X(11)70091-8 |
0.677 |
|
| 2010 |
Harrison PJ, Laatikainen LM, Tunbridge EM, Eastwood SL. Human brain weight is correlated with expression of the 'housekeeping genes' beta-2-microglobulin (β2M) and TATA-binding protein (TBP). Neuropathology and Applied Neurobiology. 36: 498-504. PMID 20831744 DOI: 10.1111/J.1365-2990.2010.01098.X |
0.633 |
|
| 2010 |
Eastwood SL, Walker M, Hyde TM, Kleinman JE, Harrison PJ. The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain. Human Molecular Genetics. 19: 2487-96. PMID 20360304 DOI: 10.1093/Hmg/Ddq130 |
0.349 |
|
| 2010 |
Arabadzisz D, Diaz-Heijtz R, Knuesel I, Weber E, Pilloud S, Dettling AC, Feldon J, Law AJ, Harrison PJ, Pryce CR. Primate early life stress leads to long-term mild hippocampal decreases in corticosteroid receptor expression. Biological Psychiatry. 67: 1106-9. PMID 20132928 DOI: 10.1016/J.Biopsych.2009.12.016 |
0.589 |
|
| 2010 |
Eastwood SL, Harrison PJ. Markers of glutamate synaptic transmission and plasticity are increased in the anterior cingulate cortex in bipolar disorder. Biological Psychiatry. 67: 1010-6. PMID 20079890 DOI: 10.1016/J.Biopsych.2009.12.004 |
0.33 |
|
| 2010 |
Verrall L, Burnet PW, Betts JF, Harrison PJ. The neurobiology of D-amino acid oxidase and its involvement in schizophrenia. Molecular Psychiatry. 15: 122-37. PMID 19786963 DOI: 10.1038/Mp.2009.99 |
0.35 |
|
| 2009 |
Deakin IH, Law AJ, Oliver PL, Schwab MH, Nave KA, Harrison PJ, Bannerman DM. Behavioural characterization of neuregulin 1 type I overexpressing transgenic mice. Neuroreport. 20: 1523-8. PMID 19829162 DOI: 10.1097/Wnr.0B013E328330F6E7 |
0.601 |
|
| 2009 |
Bristow GC, Lane TA, Walker M, Chen L, Sei Y, Hyde TM, Kleinman JE, Harrison PJ, Eastwood SL. Expression of kinase interacting with stathmin (KIS, UHMK1) in human brain and lymphoblasts: Effects of schizophrenia and genotype. Brain Research. 1301: 197-206. PMID 19747464 DOI: 10.1016/J.Brainres.2009.08.090 |
0.79 |
|
| 2009 |
Law AJ, Pei Q, Feldon J, Pryce CR, Harrison PJ. Gene expression in the anterior cingulate cortex and amygdala of adolescent marmoset monkeys following parental separations in infancy. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 761-72. PMID 19102816 DOI: 10.1017/S1461145708009723 |
0.601 |
|
| 2009 |
Law AJ, Pei Q, Walker M, Gordon-Andrews H, Weickert CS, Feldon J, Pryce CR, Harrison PJ. Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1381-94. PMID 18615010 DOI: 10.1038/Npp.2008.106 |
0.617 |
|
| 2008 |
Burnet PW, Eastwood SL, Bristow GC, Godlewska BR, Sikka P, Walker M, Harrison PJ. D-amino acid oxidase activity and expression are increased in schizophrenia. Molecular Psychiatry. 13: 658-60. PMID 18560437 DOI: 10.1038/Mp.2008.47 |
0.79 |
|
| 2008 |
Harrison PJ, Lyon L, Sartorius LJ, Burnet PW, Lane TA. The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): expression, function and involvement in schizophrenia. Journal of Psychopharmacology (Oxford, England). 22: 308-22. PMID 18541626 DOI: 10.1177/0269881108089818 |
0.36 |
|
| 2008 |
Burnet PW, Hutchinson L, von Hesling M, Gilbert EJ, Brandon NJ, Rutter AR, Hutson PH, Harrison PJ. Expression of D-serine and glycine transporters in the prefrontal cortex and cerebellum in schizophrenia. Schizophrenia Research. 102: 283-94. PMID 18400471 DOI: 10.1016/J.Schres.2008.02.009 |
0.365 |
|
| 2008 |
Sartorius LJ, Weinberger DR, Hyde TM, Harrison PJ, Kleinman JE, Lipska BK. Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2626-34. PMID 18256595 DOI: 10.1038/Sj.Npp.1301669 |
0.485 |
|
| 2008 |
Harrison PJ. Metabotropic glutamate receptor agonists for schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 192: 86-7. PMID 18245019 DOI: 10.1192/Bjp.Bp.107.045088 |
0.32 |
|
| 2008 |
Tunbridge EM, Harrison PJ, Warden DR, Johnston C, Refsum H, Smith AD. Polymorphisms in the catechol-O-methyltransferase (COMT) gene influence plasma total homocysteine levels. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 996-9. PMID 18189241 DOI: 10.1002/Ajmg.B.30700 |
0.636 |
|
| 2008 |
Harrison PJ, Tunbridge EM. Catechol-O-methyltransferase (COMT): a gene contributing to sex differences in brain function, and to sexual dimorphism in the predisposition to psychiatric disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 3037-45. PMID 17805313 DOI: 10.1038/Sj.Npp.1301543 |
0.644 |
|
| 2008 |
Eastwood SL, Harrison PJ. Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 933-45. PMID 17507910 DOI: 10.1038/Sj.Npp.1301457 |
0.363 |
|
| 2008 |
Harrison P, Verrall L, Burnet PWJ. Molecular Studies Of Nmda Receptor Modulators In Schizophrenia Schizophrenia Research. 102: 8. DOI: 10.1016/S0920-9964(08)70024-0 |
0.308 |
|
| 2007 |
Harrison PJ. Schizophrenia susceptibility genes and their neurodevelopmental implications: focus on neuregulin 1. Novartis Foundation Symposium. 288: 246-55; discussion 2. PMID 18494263 DOI: 10.1002/9780470994030.Ch17 |
0.342 |
|
| 2007 |
Verrall L, Walker M, Rawlings N, Benzel I, Kew JN, Harrison PJ, Burnet PW. d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia. The European Journal of Neuroscience. 26: 1657-69. PMID 17880399 DOI: 10.1111/J.1460-9568.2007.05769.X |
0.32 |
|
| 2007 |
Tan W, Wang Y, Gold B, Chen J, Dean M, Harrison PJ, Weinberger DR, Law AJ. Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia. The Journal of Biological Chemistry. 282: 24343-51. PMID 17565985 DOI: 10.1074/Jbc.M702953200 |
0.663 |
|
| 2007 |
Harrison PJ. Schizophrenia susceptibility genes and neurodevelopment. Biological Psychiatry. 61: 1119-20. PMID 17481418 DOI: 10.1016/J.Biopsych.2007.02.021 |
0.32 |
|
| 2007 |
Tunbridge EM, Lane TA, Harrison PJ. Expression of multiple catechol-o-methyltransferase (COMT) mRNA variants in human brain. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 834-9. PMID 17477346 DOI: 10.1002/Ajmg.B.30539 |
0.643 |
|
| 2007 |
Eastwood SL, Lyon L, George L, Andrieux A, Job D, Harrison PJ. Altered expression of synaptic protein mRNAs in STOP (MAP6) mutant mice. Journal of Psychopharmacology (Oxford, England). 21: 635-44. PMID 17050659 DOI: 10.1177/0269881106068825 |
0.319 |
|
| 2007 |
Tunbridge EM, Weickert CS, Kleinman JE, Herman MM, Chen J, Kolachana BS, Harrison PJ, Weinberger DR. Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan. Cerebral Cortex (New York, N.Y. : 1991). 17: 1206-12. PMID 16835293 DOI: 10.1093/Cercor/Bhl032 |
0.677 |
|
| 2006 |
Harrison PJ, West VA. Six degrees of separation: on the prior probability that schizophrenia susceptibility genes converge on synapses, glutamate and NMDA receptors. Molecular Psychiatry. 11: 981-3. PMID 17063182 DOI: 10.1038/Sj.Mp.4001886 |
0.307 |
|
| 2006 |
Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R, Harrison PJ, Kleinman JE, Weinberger DR. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 6747-52. PMID 16618933 DOI: 10.1073/Pnas.0602002103 |
0.664 |
|
| 2006 |
Eastwood SL, Harrison PJ. Cellular basis of reduced cortical reelin expression in schizophrenia. The American Journal of Psychiatry. 163: 540-2. PMID 16513881 DOI: 10.1176/Appi.Ajp.163.3.540 |
0.349 |
|
| 2006 |
Tunbridge EM, Harrison PJ, Weinberger DR. Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond. Biological Psychiatry. 60: 141-51. PMID 16476412 DOI: 10.1016/J.Biopsych.2005.10.024 |
0.703 |
|
| 2006 |
Harrison PJ, Law AJ. Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology. Biological Psychiatry. 60: 132-40. PMID 16442083 DOI: 10.1016/J.Biopsych.2005.11.002 |
0.638 |
|
| 2006 |
Sartorius LJ, Nagappan G, Lipska BK, Lu B, Sei Y, Ren-Patterson R, Li Z, Weinberger DR, Harrison PJ. Alternative splicing of human metabotropic glutamate receptor 3. Journal of Neurochemistry. 96: 1139-48. PMID 16417579 DOI: 10.1111/J.1471-4159.2005.03609.X |
0.462 |
|
| 2006 |
Cullen TJ, Walker MA, Eastwood SL, Esiri MM, Harrison PJ, Crow TJ. Anomalies of asymmetry of pyramidal cell density and structure in dorsolateral prefrontal cortex in schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 188: 26-31. PMID 16388066 DOI: 10.1192/Bjp.Bp.104.008169 |
0.318 |
|
| 2006 |
Tunbridge EM, Weinberger DR, Harrison PJ. A novel protein isoform of catechol O-methyltransferase (COMT): brain expression analysis in schizophrenia and bipolar disorder and effect of Val158Met genotype. Molecular Psychiatry. 11: 116-7. PMID 16247488 DOI: 10.1038/Sj.Mp.4001767 |
0.699 |
|
| 2005 |
Eastwood SL, Salih T, Harrison PJ. Differential expression of calcineurin A subunit mRNA isoforms during rat hippocampal and cerebellar development. The European Journal of Neuroscience. 22: 3017-24. PMID 16367768 DOI: 10.1111/J.1460-9568.2005.04518.X |
0.325 |
|
| 2005 |
Eastwood SL, Harrison PJ. Interstitial white matter neuron density in the dorsolateral prefrontal cortex and parahippocampal gyrus in schizophrenia. Schizophrenia Research. 79: 181-8. PMID 16076548 DOI: 10.1016/J.Schres.2005.07.001 |
0.305 |
|
| 2005 |
Sodhi MS, Airey DC, Lambert W, Burnet PW, Harrison PJ, Sanders-Bush E. A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts. Molecular Pharmacology. 68: 711-9. PMID 15917433 DOI: 10.1124/Mol.105.014134 |
0.662 |
|
| 2005 |
Eastwood SL, Burnet PW, Harrison PJ. Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia. Biological Psychiatry. 57: 702-10. PMID 15820226 DOI: 10.1016/J.Biopsych.2004.12.029 |
0.351 |
|
| 2005 |
Owen MJ, O'Donovan MC, Harrison PJ. Schizophrenia: a genetic disorder of the synapse? Bmj (Clinical Research Ed.). 330: 158-9. PMID 15661762 DOI: 10.1136/Bmj.330.7484.158 |
0.358 |
|
| 2005 |
Eastwood SL, Harrison PJ. Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: further evidence for a synaptic pathology affecting glutamate neurons. Schizophrenia Research. 73: 159-72. PMID 15653259 DOI: 10.1016/J.Schres.2004.05.010 |
0.339 |
|
| 2005 |
Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Molecular Psychiatry. 10: 40-68; image 5. PMID 15263907 DOI: 10.1038/Sj.Mp.4001558 |
0.503 |
|
| 2005 |
LAW AJ, WEICKERT CS, HYDE TM, KLEINMAN JE, HARRISON PJ. Dr. Law and Colleagues Reply American Journal of Psychiatry. 162: 1389-a-1390. DOI: 10.1176/Appi.Ajp.162.7.1389-A |
0.526 |
|
| 2005 |
Harrison PJ, Weinberger DR. Erratum: Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence Molecular Psychiatry. 10: 420-420. DOI: 10.1038/Sj.Mp.4001630 |
0.448 |
|
| 2004 |
Law AJ, Weickert CS, Hyde TM, Kleinman JE, Harrison PJ. Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines. The American Journal of Psychiatry. 161: 1848-55. PMID 15465982 DOI: 10.1176/Ajp.161.10.1848 |
0.627 |
|
| 2004 |
Law AJ, Shannon Weickert C, Hyde TM, Kleinman JE, Harrison PJ. Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain. Neuroscience. 127: 125-36. PMID 15219675 DOI: 10.1016/J.Neuroscience.2004.04.026 |
0.611 |
|
| 2004 |
Harrison PJ. The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications. Psychopharmacology. 174: 151-62. PMID 15205886 DOI: 10.1007/S00213-003-1761-Y |
0.357 |
|
| 2004 |
Tunbridge EM, Bannerman DM, Sharp T, Harrison PJ. Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5331-5. PMID 15190105 DOI: 10.1523/Jneurosci.1124-04.2004 |
0.704 |
|
| 2004 |
Law AJ, Hutchinson LJ, Burnet PW, Harrison PJ. Antipsychotics increase microtubule-associated protein 2 mRNA but not spinophilin mRNA in rat hippocampus and cortex. Journal of Neuroscience Research. 76: 376-82. PMID 15079866 DOI: 10.1002/Jnr.20092 |
0.617 |
|
| 2004 |
Pooley EC, Fairburn CG, Cooper Z, Sodhi MS, Cowen PJ, Harrison PJ. A 5-HT2C receptor promoter polymorphism (HTR2C - 759C/T) is associated with obesity in women, and with resistance to weight loss in heterozygotes. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 126: 124-7. PMID 15048662 DOI: 10.1002/Ajmg.B.20143 |
0.505 |
|
| 2004 |
Tunbridge E, Burnet PW, Sodhi MS, Harrison PJ. Catechol-o-methyltransferase (COMT) and proline dehydrogenase (PRODH) mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression. Synapse (New York, N.Y.). 51: 112-8. PMID 14618678 DOI: 10.1002/Syn.10286 |
0.743 |
|
| 2004 |
Harrison PJ, Weinberger DR. Schizophrenia genes within cortical neural circuits Molecular Psychiatry. 10: 5-5. DOI: 10.1038/Sj.Mp.4001625 |
0.439 |
|
| 2003 |
Law AJ, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Changes in NMDA receptor subunit mRNAs and cyclophilin mRNA during development of the human hippocampus. Annals of the New York Academy of Sciences. 1003: 426-30. PMID 14684479 DOI: 10.1196/Annals.1300.043 |
0.57 |
|
| 2003 |
Harrison PJ, Law AJ, Eastwood SL. Glutamate receptors and transporters in the hippocampus in schizophrenia. Annals of the New York Academy of Sciences. 1003: 94-101. PMID 14684437 DOI: 10.1196/Annals.1300.006 |
0.626 |
|
| 2003 |
Law AJ, Harrison PJ. The distribution and morphology of prefrontal cortex pyramidal neurons identified using anti-neurofilament antibodies SMI32, N200 and FNP7. Normative data and a comparison in subjects with schizophrenia, bipolar disorder or major depression. Journal of Psychiatric Research. 37: 487-99. PMID 14563380 DOI: 10.1016/S0022-3956(03)00075-X |
0.603 |
|
| 2003 |
Harrison PJ, Freemantle N, Geddes JR. Meta-analysis of brain weight in schizophrenia. Schizophrenia Research. 64: 25-34. PMID 14511798 DOI: 10.1016/S0920-9964(02)00502-9 |
0.323 |
|
| 2003 |
Harris LW, Sharp T, Gartlon J, Jones DN, Harrison PJ. Long-term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism. The European Journal of Neuroscience. 18: 1706-10. PMID 14511349 DOI: 10.1046/J.1460-9568.2003.02902.X |
0.493 |
|
| 2003 |
Law AJ, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation. The European Journal of Neuroscience. 18: 1197-205. PMID 12956718 DOI: 10.1046/J.1460-9568.2003.02850.X |
0.602 |
|
| 2003 |
Eastwood SL, Harrison PJ. Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis. Molecular Psychiatry. 8: 769, 821-31. PMID 12931209 DOI: 10.1038/Sj.Mp.4001399 |
0.34 |
|
| 2003 |
Highley JR, Walker MA, Crow TJ, Esiri MM, Harrison PJ. Low medial and lateral right pulvinar volumes in schizophrenia: a postmortem study. The American Journal of Psychiatry. 160: 1177-9. PMID 12777280 DOI: 10.1176/Appi.Ajp.160.6.1177 |
0.312 |
|
| 2003 |
Eastwood SL, Law AJ, Everall IP, Harrison PJ. The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology. Molecular Psychiatry. 8: 148-55. PMID 12610647 DOI: 10.1038/Sj.Mp.4001233 |
0.627 |
|
| 2003 |
Cullen TJ, Walker MA, Parkinson N, Craven R, Crow TJ, Esiri MM, Harrison PJ. A postmortem study of the mediodorsal nucleus of the thalamus in schizophrenia. Schizophrenia Research. 60: 157-66. PMID 12591579 DOI: 10.1016/S0920-9964(02)00297-9 |
0.326 |
|
| 2003 |
Harrison PJ, Owen MJ. Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet. 361: 417-9. PMID 12573388 DOI: 10.1016/S0140-6736(03)12379-3 |
0.334 |
|
| 2003 |
Law A, Shannon-Weickert C, Hyde T, Kleinman J, Harrison P. Does synaptic pathology in schizophrenia involve a selective dendritic spine deficit? A study of spinophilin and MAP2 gene expression in the hippocampus Schizophrenia Research. 60: 72-73. DOI: 10.1016/S0920-9964(03)80601-1 |
0.605 |
|
| 2003 |
Eastwood S, Harrison P. Reelin MRNA is decreased in neurons of the hippocampus and temporal cortex in schizophrenia: A cellular in situ hybridisation study Schizophrenia Research. 60: 71. DOI: 10.1016/S0920-9964(03)80595-9 |
0.32 |
|
| 2003 |
Harrison P, Eastwood S. Vesicular glutamate transporter (VGLUT) gene expression provides further evidence for glutamatergic synaptic pathology in the hippocampus in schizophrenia Schizophrenia Research. 60: 62-63. DOI: 10.1016/S0920-9964(03)80571-6 |
0.319 |
|
| 2003 |
Harris L, Sharp T, Harrison P. A neurodevelopmental, glutamatergic model relevant to schizophrenia? MK801-induced apoptosis in the neonatal rat produces molecular changes in the adult brain Schizophrenia Research. 60: 57-58. DOI: 10.1016/S0920-9964(03)80557-1 |
0.484 |
|
| 2003 |
Harrison P, Owen M. Genes for schizophrenia The Lancet. 361: 1829-1830. DOI: 10.1016/S0140-6736(03)13434-4 |
0.318 |
|
| 2002 |
Highley JR, Walker MA, Esiri MM, Crow TJ, Harrison PJ. Asymmetry of the uncinate fasciculus: a post-mortem study of normal subjects and patients with schizophrenia. Cerebral Cortex (New York, N.Y. : 1991). 12: 1218-24. PMID 12379610 DOI: 10.1093/Cercor/12.11.1218 |
0.308 |
|
| 2002 |
East SZ, Burnet PW, Kerwin RW, Harrison PJ. An RT-PCR study of 5-HT(6) and 5-HT(7) receptor mRNAs in the hippocampal formation and prefrontal cortex in schizophrenia. Schizophrenia Research. 57: 15-26. PMID 12165372 DOI: 10.1016/S0920-9964(01)00323-1 |
0.499 |
|
| 2002 |
East SZ, Burnet PW, Leslie RA, Roberts JC, Harrison PJ. 5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: autoradiographic studies with [125I]SB-258585. Synapse (New York, N.Y.). 45: 191-9. PMID 12112397 DOI: 10.1002/Syn.10097 |
0.328 |
|
| 2002 |
Harrison PJ. The neuropathology of primary mood disorder. Brain : a Journal of Neurology. 125: 1428-49. PMID 12076995 DOI: 10.1093/Brain/Awf149 |
0.323 |
|
| 2002 |
Meller R, Harrison PJ, Sharp T. Studies on the role of calcium in the 5-HT-stimulated release of glutamate from C6 glioma cells. European Journal of Pharmacology. 445: 13-9. PMID 12065189 DOI: 10.1016/S0014-2999(02)01718-1 |
0.446 |
|
| 2002 |
Meller R, Harrison PJ, Elliott JM, Sharp T. In vitro evidence that 5-hydroxytryptamine increases efflux of glial glutamate via 5-HT(2A) receptor activation. Journal of Neuroscience Research. 67: 399-405. PMID 11813245 DOI: 10.1002/Jnr.10126 |
0.447 |
|
| 2002 |
Burnet P, Eastwood S, East S, Crossland N, Harrison P. Serotonin receptor gene expression in the pathology of schizophrenia European Psychiatry. 17: 24. DOI: 10.1016/S0924-9338(02)80110-9 |
0.339 |
|
| 2001 |
Harrison PJ, Eastwood SL. Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia. Hippocampus. 11: 508-19. PMID 11732704 DOI: 10.1002/Hipo.1067 |
0.351 |
|
| 2001 |
Eastwood SL, Harrison PJ. Synaptic pathology in the anterior cingulate cortex in schizophrenia and mood disorders. A review and a Western blot study of synaptophysin, GAP-43 and the complexins. Brain Research Bulletin. 55: 569-78. PMID 11576753 DOI: 10.1016/S0361-9230(01)00530-5 |
0.336 |
|
| 2001 |
Eastwood SL, Cotter D, Harrison PJ. Cerebellar synaptic protein expression in schizophrenia. Neuroscience. 105: 219-29. PMID 11483314 DOI: 10.1016/S0306-4522(01)00141-5 |
0.346 |
|
| 2001 |
Sodhi MS, Burnet PW, Makoff AJ, Kerwin RW, Harrison PJ. RNA editing of the 5-HT(2C) receptor is reduced in schizophrenia. Molecular Psychiatry. 6: 373-9. PMID 11443520 DOI: 10.1038/Sj.Mp.4000920 |
0.641 |
|
| 2001 |
Highley JR, Walker MA, Esiri MM, McDonald B, Harrison PJ, Crow TJ. Schizophrenia and the frontal lobes: post-mortem stereological study of tissue volume. The British Journal of Psychiatry : the Journal of Mental Science. 178: 337-43. PMID 11282813 DOI: 10.1192/Bjp.178.4.337 |
0.304 |
|
| 2001 |
Burnet PW, Miller R, Lewis LJ, Pei Q, Sharp T, Harrison PJ. Electroconvulsive shock increases tachykinin NK(1) receptors, but not the encoding mRNA, in rat cortex. European Journal of Pharmacology. 413: 213-9. PMID 11226395 DOI: 10.1016/S0014-2999(01)00777-4 |
0.477 |
|
| 2000 |
Geddes J, Freemantle N, Harrison P, Bebbington P. Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis Bmj. 321: 1371-1376. PMID 11099280 DOI: 10.1136/Bmj.321.7273.1371 |
0.309 |
|
| 2000 |
Harrison PJ. Dopamine and schizophrenia--proof at last? Lancet. 356: 958-9. PMID 11041394 DOI: 10.1016/S0140-6736(00)02710-0 |
0.31 |
|
| 2000 |
Rabiner EA, Gunn RN, Castro ME, Sargent PA, Cowen PJ, Koepp MJ, Meyer JH, Bench CJ, Harrison PJ, Pazos A, Sharp T, Grasby PM. beta-blocker binding to human 5-HT(1A) receptors in vivo and in vitro: implications for antidepressant therapy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 285-93. PMID 10942852 DOI: 10.1016/S0893-133X(00)00109-3 |
0.441 |
|
| 2000 |
Castro ME, Harrison PJ, Pazos A, Sharp T. Affinity of (+/-)-pindolol, (-)-penbutolol, and (-)-tertatolol for pre- and postsynaptic serotonin 5-HT(1A) receptors in human and rat brain. Journal of Neurochemistry. 75: 755-62. PMID 10899952 DOI: 10.1046/J.1471-4159.2000.0750755.X |
0.452 |
|
| 2000 |
Eastwood SL, Harrison PJ. Hippocampal synaptic pathology in schizophrenia, bipolar disorder and major depression: a study of complexin mRNAs. Molecular Psychiatry. 5: 425-32. PMID 10889554 DOI: 10.1038/Sj.Mp.4000741 |
0.354 |
|
| 2000 |
Eastwood SL, Cairns NJ, Harrison PJ. Synaptophysin gene expression in schizophrenia. Investigation of synaptic pathology in the cerebral cortex. The British Journal of Psychiatry : the Journal of Mental Science. 176: 236-42. PMID 10755070 DOI: 10.1192/Bjp.176.3.236 |
0.353 |
|
| 2000 |
Burnet PW, Harrison PJ. Substance P (NK1) receptors in the cingulate cortex in unipolar and bipolar mood disorder and schizophrenia. Biological Psychiatry. 47: 80-3. PMID 10650452 DOI: 10.1016/S0006-3223(99)00264-4 |
0.328 |
|
| 2000 |
Sodhi M, Makoff A, Crossland N, Kerwin R, Harrison P. RNA editing of the 5-HT2C receptor in human brain Schizophrenia Research. 41: 253. DOI: 10.1016/S0920-9964(00)90939-3 |
0.462 |
|
| 2000 |
Harrison P, Baker K, Eastwood S. Cerebellar serotonin 5-HT2A receptors in schizophrenia Schizophrenia Research. 41: 252-253. DOI: 10.1016/S0920-9964(00)90937-X |
0.317 |
|
| 2000 |
Walker M, Highley R, Harrison P, Esiri M, Crow T. Structure of frontal lobe gyri in schizophrenia: A postmortem study Schizophrenia Research. 41: 111. DOI: 10.1016/S0920-9964(00)90565-6 |
0.305 |
|
| 2000 |
Cullen TJ, Walker MA, Roberts H, Crow TJ, Harrison P, Esiri M. The mediodorsal nucleus of the thalamus in schizophrenia: A post-mortem study Schizophrenia Research. 41: 5. DOI: 10.1016/S0920-9964(00)90318-9 |
0.31 |
|
| 1999 |
Burnet PW, Sharp T, LeCorre SM, Harrison PJ. Expression of 5-HT receptors and the 5-HT transporter in rat brain after electroconvulsive shock. Neuroscience Letters. 277: 79-82. PMID 10624814 DOI: 10.1016/S0304-3940(99)00857-5 |
0.46 |
|
| 1999 |
Harrison PJ. The neuropathological effects of antipsychotic drugs. Schizophrenia Research. 40: 87-99. PMID 10593448 DOI: 10.1016/S0920-9964(99)00065-1 |
0.32 |
|
| 1999 |
Harrison PJ. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain : a Journal of Neurology. 122: 593-624. PMID 10219775 DOI: 10.1093/Brain/122.4.593 |
0.361 |
|
| 1999 |
Harrison PJ. Brains at risk of schizophrenia. Lancet. 353: 3-4. PMID 10023939 DOI: 10.1016/S0140-6736(05)74878-9 |
0.305 |
|
| 1998 |
Eastwood SL, Harrison PJ. Hippocampal and cortical growth-associated protein-43 messenger RNA in schizophrenia. Neuroscience. 86: 437-48. PMID 9881859 DOI: 10.1016/S0306-4522(98)00040-2 |
0.318 |
|
| 1998 |
Harrison PJ, Eastwood SL. Preferential involvement of excitatory neurons in medial temporal lobe in schizophrenia. Lancet. 352: 1669-73. PMID 9853440 DOI: 10.1016/S0140-6736(98)03341-8 |
0.339 |
|
| 1998 |
Harrison PJ. Schizophrenia neuropathology: tortoises and hares. Journal of Neurology, Neurosurgery, and Psychiatry. 65: 432. PMID 9771759 DOI: 10.1136/Jnnp.65.4.432 |
0.335 |
|
| 1998 |
Harrison P, Eastwood S. Synaptic pathology in schizophrenia: Differential involvement of the complexins Schizophrenia Research. 29: 88. DOI: 10.1016/S0920-9964(97)88520-9 |
0.3 |
|
| 1997 |
Harrison PJ, Burnet PW, Falkai P, Bogerts B, Eastwood SL. Gene expression and neuronal activity in schizophrenia: a study of polyadenylated mRNA in the hippocampal formation and cerebral cortex. Schizophrenia Research. 26: 93-102. PMID 9323338 DOI: 10.1016/S0920-9964(97)00048-0 |
0.328 |
|
| 1997 |
Le Corre SM, Burnet PW, Meller R, Sharp T, Harrison PJ. Critical issues in the antisense inhibition of brain gene expression in vivo: experiences targetting the 5-HT1A receptor. Neurochemistry International. 31: 349-62. PMID 9246678 DOI: 10.1016/S0197-0186(96)00106-4 |
0.49 |
|
| 1997 |
Eastwood SL, Heffernan J, Harrison PJ. Chronic haloperidol treatment differentially affects the expression of synaptic and neuronal plasticity-associated genes. Molecular Psychiatry. 2: 322-9. PMID 9246673 DOI: 10.1038/Sj.Mp.4000238 |
0.308 |
|
| 1997 |
Le Corre S, Sharp T, Young AH, Harrison PJ. Increase of 5-HT7 (serotonin-7) and 5-HT1A (serotonin-1A) receptor mRNA expression in rat hippocampus after adrenalectomy. Psychopharmacology. 130: 368-74. PMID 9160853 DOI: 10.1007/S002130050252 |
0.464 |
|
| 1997 |
Harrison PJ. Schizophrenia: a disorder of neurodevelopment? Current Opinion in Neurobiology. 7: 285-9. PMID 9142763 DOI: 10.1016/S0959-4388(97)80018-9 |
0.341 |
|
| 1997 |
Porter RH, Eastwood SL, Harrison PJ. Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia. Brain Research. 751: 217-31. PMID 9099808 DOI: 10.1016/S0006-8993(96)01404-7 |
0.318 |
|
| 1997 |
Harrison PJ, Burnet PW. The 5-HT2A (serotonin2A) receptor gene in the aetiology, pathophysiology and pharmacotherapy of schizophrenia. Journal of Psychopharmacology (Oxford, England). 11: 18-20. PMID 9097886 DOI: 10.1177/026988119701100105 |
0.331 |
|
| 1997 |
Eastwood SL, Kerwin RW, Harrison PJ. Immunoautoradiographic evidence for a loss of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate-preferring non-N-methyl-D-aspartate glutamate receptors within the medial temporal lobe in schizophrenia. Biological Psychiatry. 41: 636-43. PMID 9066986 DOI: 10.1016/S0006-3223(96)00220-X |
0.526 |
|
| 1997 |
Eastwood SL, Burnet PW, Harrison PJ. GluR2 glutamate receptor subunit flip and flop isoforms are decreased in the hippocampal formation in schizophrenia: a reverse transcriptase-polymerase chain reaction (RT-PCR) study. Brain Research. Molecular Brain Research. 44: 92-8. PMID 9030702 DOI: 10.1016/S0169-328X(96)00195-7 |
0.323 |
|
| 1997 |
Harrison PJ, Eastwood SL. Gene expression markers of neuronal activity and plasticity in the cerebral cortex in schizophrenia Schizophrenia Research. 24: 86-87. DOI: 10.1016/S0920-9964(97)82234-7 |
0.326 |
|
| 1997 |
Burnet PW, Harrison PJ. 5-HT (serotonin) receptor gene expression in the aetiology, pathophysiology and pharmacotherapy of schizophrenia Schizophrenia Research. 24: 86. DOI: 10.1016/S0920-9964(97)82232-3 |
0.311 |
|
| 1996 |
Harrison PJ. Advances in post mortem molecular neurochemistry and neuropathology: examples from schizophrenia research. British Medical Bulletin. 52: 527-38. PMID 8949255 DOI: 10.1093/Oxfordjournals.Bmb.A011565 |
0.351 |
|
| 1996 |
Burnet PW, Eastwood SL, Harrison PJ. 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 442-55. PMID 8914117 DOI: 10.1016/S0893-133X(96)00053-X |
0.321 |
|
| 1996 |
Harrison PJ, Geddes JR. Schizophrenia and the 5-HT2A receptor gene. Lancet. 347: 1274. PMID 8622497 DOI: 10.1016/S0140-6736(96)90931-9 |
0.326 |
|
| 1996 |
Harrison P, Eastwood S, Esiri M, Zaidel D. Cytoarchitectural hippocampal asymmetries in schizophrenia Schizophrenia Research. 18: 180. DOI: 10.1016/0920-9964(96)85566-6 |
0.31 |
|
| 1996 |
Eastwood S, Porter R, Burnet P, Kerwin R, Harrison P. Non-NMDA glutamate receptor expression in schizophrenia Schizophrenia Research. 18: 174. DOI: 10.1016/0920-9964(96)85549-6 |
0.507 |
|
| 1995 |
Eastwood SL, Harrison PJ. Decreased synaptophysin in the medial temporal lobe in schizophrenia demonstrated using immunoautoradiography. Neuroscience. 69: 339-43. PMID 8552231 DOI: 10.1016/0306-4522(95)00324-C |
0.321 |
|
| 1995 |
Zaidel DW, Esiri MM, Eastwood SL, Harrison PJ. Asymmetrical hippocampal circuitry and schizophrenia. Lancet. 345: 656-7. PMID 7898213 DOI: 10.1016/S0140-6736(95)90562-6 |
0.311 |
|
| 1995 |
Burnet PW, Mead A, Eastwood SL, Lacey K, Harrison PJ, Sharp T. Repeated ECS differentially affects rat brain 5-HT1A and 5-HT2A receptor expression. Neuroreport. 6: 901-4. PMID 7612879 DOI: 10.1097/00001756-199504190-00019 |
0.472 |
|
| 1995 |
Eastwood SL, McDonald B, Burnet PW, Beckwith JP, Kerwin RW, Harrison PJ. Decreased expression of mRNAs encoding non-NMDA glutamate receptors GluR1 and GluR2 in medial temporal lobe neurons in schizophrenia. Brain Research. Molecular Brain Research. 29: 211-23. PMID 7609609 DOI: 10.1016/0169-328X(94)00247-C |
0.523 |
|
| 1995 |
Harrison PJ. On the neuropathology of schizophrenia and its dementia: neurodevelopmental, neurodegenerative, or both? Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 4: 1-12. PMID 7600178 DOI: 10.1006/Neur.1995.0001 |
0.316 |
|
| 1995 |
Eastwood SL, Burnet PW, Harrison PJ. Altered synaptophysin expression as a marker of synaptic pathology in schizophrenia. Neuroscience. 66: 309-19. PMID 7477874 DOI: 10.1016/0306-4522(94)00586-T |
0.319 |
|
| 1995 |
Kerwin R, Harrison P. Loss of non nmda receptors in medial temporal lobe—-a robust neurochemical finding: autoradiographical, gene expression and immunocytochemical findings Schizophrenia Research. 15: 62. DOI: 10.1016/0920-9964(95)95196-G |
0.489 |
|
| 1995 |
Burnet P, Harrison P. 5-HT1A and 5-HT2A receptor gene expression in schizophrenia Schizophrenia Research. 15: 55. DOI: 10.1016/0920-9964(95)95176-A |
0.33 |
|
| 1995 |
Beckwith J, McLaughlin D, Stefanis N, Eastwood S, Harrison P, Kerwin R. Expression of developmentally specific isoforms on non-NMDA mRNAs in the hippocampus of schizophrenics Schizophrenia Research. 15: 53-54. DOI: 10.1016/0920-9964(95)95170-E |
0.483 |
|
| 1994 |
Eastwood SL, Story P, Burnet PW, Heath P, Harrison PJ. Differential changes in glutamate receptor subunit messenger RNAs in rat brain after haloperidol treatment. Journal of Psychopharmacology (Oxford, England). 8: 196-203. PMID 22298625 DOI: 10.1177/026988119400800402 |
0.307 |
|
| 1994 |
Eastwood SL, Burnet PW, Beckwith J, Kerwin RW, Harrison PJ. AMPA glutamate receptors and their flip and flop mRNAs in human hippocampus. Neuroreport. 5: 1325-8. PMID 7919190 DOI: 10.1097/00001756-199406000-00007 |
0.499 |
|
| 1993 |
McLaughlin D, Beckwith J, Harrison P, Kerwin R. Expression of developmentally specific forms of glutamate receptor mRNAs in the hippocampus of schizophrenics Schizophrenia Research. 9: 223-224. DOI: 10.1016/0920-9964(93)90487-4 |
0.491 |
|
| 1993 |
Eastwood S, Falkai P, Bogerts B, Kerwin R, Harrison P. Hippocampal synaptophysin gene expression in schizophrenia Schizophrenia Research. 9: 217-218. DOI: 10.1016/0920-9964(93)90470-4 |
0.525 |
|
| 1993 |
Harrison PJ, Lewis DA, Kleinman JE. Neuropathology of Schizophrenia Journal of the Neurological Sciences. 120: 372-392. DOI: 10.1016/0022-510X(93)90008-M |
0.306 |
|
| 1991 |
Harrison PJ, McLaughlin D, Kerwin RW. Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. Lancet. 337: 450-2. PMID 1671470 DOI: 10.1016/0140-6736(91)93392-M |
0.541 |
|
| Show low-probability matches. |