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Lijun Sun - Publications

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Innate Immunity
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tan X, Sun L, Chen J, Chen ZJ. Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids. Annual Review of Microbiology. 72: 447-478. PMID 30200854 DOI: 10.1146/Annurev-Micro-102215-095605  0.305
2017 Wang H, Hu S, Chen X, Shi H, Chen C, Sun L, Chen ZJ. cGAS is essential for the antitumor effect of immune checkpoint blockade. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137885 DOI: 10.1073/Pnas.1621363114  0.309
2016 Chen Q, Sun L, Chen ZJ. Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing. Nature Immunology. 17: 1142-1149. PMID 27648547 DOI: 10.1038/Ni.3558  0.325
2014 Zhang X, Wu J, Du F, Xu H, Sun L, Chen Z, Brautigam CA, Chen ZJ. The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop Cell Reports. 6: 421-430. PMID 24462292 DOI: 10.1016/J.Celrep.2014.01.003  0.303
2013 Li XD, Wu J, Gao D, Wang H, Sun L, Chen ZJ. Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science (New York, N.Y.). 341: 1390-4. PMID 23989956 DOI: 10.1126/Science.1244040  0.313
2013 Liu S, Chen J, Cai X, Wu J, Chen X, Wu YT, Sun L, Chen ZJ. MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife. 2: e00785. PMID 23951545 DOI: 10.7554/Elife.00785  0.365
2013 Zhang X, Shi H, Wu J, Zhang X, Sun L, Chen C, Chen ZJ. Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Molecular Cell. 51: 226-35. PMID 23747010 DOI: 10.1016/J.Molcel.2013.05.022  0.304
2013 Sun L, Wu J, Du F, Chen X, Chen ZJ. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway Science. 339: 786-791. PMID 23258413 DOI: 10.1126/Science.1232458  0.321
2013 Wu J, Sun L, Chen X, Du F, Shi H, Chen C, Chen ZJ. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science (New York, N.Y.). 339: 826-30. PMID 23258412 DOI: 10.1126/Science.1229963  0.306
2011 Hou F, Sun L, Zheng H, Skaug B, Jiang QX, Chen ZJ. MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell. 146: 448-61. PMID 21782231 DOI: 10.1016/J.Cell.2011.06.041  0.34
2010 Zeng W, Sun L, Jiang X, Chen X, Hou F, Adhikari A, Xu M, Chen ZJ. Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell. 141: 315-30. PMID 20403326 DOI: 10.1016/J.Cell.2010.03.029  0.322
2010 Sun L, Liu S, Chen ZJ. SnapShot: Pathways of Antiviral Innate Immunity Cell. 140: 436-436.e2. PMID 20144765 DOI: 10.1016/J.Cell.2010.01.041  0.321
2009 Zeng W, Xu M, Liu S, Sun L, Chen ZJ. Key Role of Ubc5 and Lysine-63 Polyubiquitination in Viral Activation of IRF3 Molecular Cell. 36: 315-325. PMID 19854139 DOI: 10.1016/J.Molcel.2009.09.037  0.359
2009 Xia ZP, Sun L, Chen X, Pineda G, Jiang X, Adhikari A, Zeng W, Chen ZJ. Direct activation of protein kinases by unanchored polyubiquitin chains. Nature. 461: 114-9. PMID 19675569 DOI: 10.1038/Nature08247  0.316
2008 Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature. 451: 573-7. PMID 18200010 DOI: 10.1038/Nature06501  0.337
2007 Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature. 446: 916-920. PMID 17392790 DOI: 10.1038/Nature05732  0.344
2006 Sun Q, Sun L, Liu HH, Chen X, Seth RB, Forman J, Chen ZJ. The Specific and Essential Role of MAVS in Antiviral Innate Immune Responses Immunity. 24: 633-642. PMID 16713980 DOI: 10.1016/J.Immuni.2006.04.004  0.347
2006 Seth RB, Sun L, Chen ZJ. Antiviral innate immunity pathways. Cell Research. 16: 141-147. PMID 16474426 DOI: 10.1038/Sj.Cr.7310019  0.341
2005 Seth RB, Sun L, Ea CK, Chen ZJ. Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3 Cell. 122: 669-682. PMID 16125763 DOI: 10.1016/J.Cell.2005.08.012  0.352
2004 Ea CK, Sun L, Inoue JI, Chen ZJ. TIFA activates IκB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6 Proceedings of the National Academy of Sciences of the United States of America. 101: 15318-15323. PMID 15492226 DOI: 10.1073/Pnas.0404132101  0.314
2004 Sun L, Deng L, Ea CK, Xia ZP, Chen ZJ. The TRAF6 Ubiquitin Ligase and TAK1 Kinase Mediate IKK Activation by BCL10 and MALT1 in T Lymphocytes Molecular Cell. 14: 289-301. PMID 15125833 DOI: 10.1016/S1097-2765(04)00236-9  0.322
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