James J. Lah - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
Neuroscience Biology

189 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Guo Q, Ping L, Dammer EB, Yin L, Xu K, Shantaraman A, Fox EJ, Golde TE, Johnson ECB, Roberts BR, Lah JJ, Levey AI, Seyfried NT. Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research Square. PMID 38464223 DOI: 10.21203/rs.3.rs-3933136/v1  0.316
2024 Christensen GM, Li Z, Liang D, Ebelt S, Gearing M, Levey AI, Lah JJ, Wingo A, Wingo T, Hüls A. Association of PM Exposure and Alzheimer Disease Pathology in Brain Bank Donors-Effect Modification by Genotype. Neurology. 102: e209162. PMID 38382009 DOI: 10.1212/WNL.0000000000209162  0.309
2024 Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L. Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 38328211 DOI: 10.1101/2024.01.23.576728  0.381
2024 Chemparathy A, Le Guen Y, Chen S, Lee EG, Leong L, Gorzynski JE, Jensen TD, Ferrasse A, Xu G, Xiang H, Belloy ME, Kasireddy N, Peña-Tauber A, Williams K, Stewart I, ... ... Lah JJ, et al. APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's disease pathology. Neuron. PMID 38301647 DOI: 10.1016/j.neuron.2024.01.008  0.347
2024 Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, et al. Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. Medrxiv : the Preprint Server For Health Sciences. PMID 38260316 DOI: 10.1101/2024.01.10.24301099  0.386
2023 Suridjan I, van der Flier WM, Monsch AU, Burnie N, Baldor R, Sabbagh M, Vilaseca J, Cai D, Carboni M, Lah JJ. Blood-based biomarkers in Alzheimer's disease: Future directions for implementation. Alzheimer's & Dementia (Amsterdam, Netherlands). 15: e12508. PMID 38058357 DOI: 10.1002/dad2.12508  0.308
2023 Dammer EB, Shantaraman A, Ping L, Duong DM, Gerasimov ES, Ravindran SP, Gudmundsdottir V, Frick EA, Gomez GT, Walker KA, Emilsson V, Jennings LL, Gudnason V, Western D, Cruchaga C, ... Lah JJ, et al. Proteomic Network Analysis of Alzheimer's Disease Cerebrospinal Fluid Reveals Alterations Associated with ε4 Genotype and Atomoxetine Treatment. Medrxiv : the Preprint Server For Health Sciences. PMID 37961720 DOI: 10.1101/2023.10.29.23297651  0.355
2023 Higginbotham L, Carter EK, Dammer EB, Haque RU, Johnson ECB, Duong DM, Yin L, De Jager PL, Bennett DA, Felsky D, Tio ES, Lah JJ, Levey AI, Seyfried NT. Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment. Neurobiology of Disease. 106286. PMID 37689213 DOI: 10.1016/j.nbd.2023.106286  0.307
2023 Haque R, Watson CM, Liu J, Carter EK, Duong DM, Lah JJ, Wingo AP, Roberts BR, Johnson ECB, Saykin AJ, Shaw LM, Seyfried NT, Wingo TS, Levey AI. A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease. Science Translational Medicine. 15: eadg4122. PMID 37672565 DOI: 10.1126/scitranslmed.adg4122  0.35
2023 Johnson ECB, Bian S, Haque RU, Carter EK, Watson CM, Gordon BA, Ping L, Duong DM, Epstein MP, McDade E, Barthélemy NR, Karch CM, Xiong C, Cruchaga C, Perrin RJ, ... ... Lah JJ, et al. Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature Medicine. PMID 37550416 DOI: 10.1038/s41591-023-02476-4  0.385
2023 Chemparathy A, Guen YL, Chen S, Lee EG, Leong L, Gorzynski J, Xu G, Belloy M, Kasireddy N, Tauber AP, Williams K, Stewart I, Wingo T, Lah J, Jayadev S, et al. loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's Disease pathology. Medrxiv : the Preprint Server For Health Sciences. PMID 37547016 DOI: 10.1101/2023.07.20.23292771  0.345
2023 Modeste ES, Ping L, Watson CM, Duong DM, Dammer EB, Johnson ECB, Roberts BR, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease. Molecular Neurodegeneration. 18: 48. PMID 37468915 DOI: 10.1186/s13024-023-00638-z  0.316
2023 Watson CM, Dammer EB, Ping L, Duong DM, Modeste E, Carter EK, Johnson ECB, Levey AI, Lah JJ, Roberts BR, Seyfried NT. Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific Data. 10: 261. PMID 37160957 DOI: 10.1038/s41597-023-02158-3  0.369
2023 Christensen GM, Li Z, Liang D, Ebelt S, Gearing M, Levey AI, Lah JJ, Wingo AP, Wingo TS, Huels A. Fine particulate air pollution and neuropathology markers of Alzheimer's disease in donors with and without APOE ε4 alleles - results from an autopsy cohort. Medrxiv : the Preprint Server For Health Sciences. PMID 37066193 DOI: 10.1101/2023.04.07.23288288  0.307
2023 Lah J, Tandon R, Zhao L, Watson C, Elmor M, Heilman C, Sanders K, Hales C, Yang H, Loring D, Goldstein F, Hanfelt J, Duong D, Johnson ECB, Wingo A, et al. Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease. Research Square. PMID 36909654 DOI: 10.21203/rs.3.rs-2577025/v1  0.36
2023 Tandon R, Levey AI, Lah JJ, Seyfried NT, Mitchell CS. Machine Learning Selection of Most Predictive Brain Proteins Suggests Role of Sugar Metabolism in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 36776048 DOI: 10.3233/JAD-220683  0.346
2022 Del Campo M, Peeters CFW, Johnson ECB, Vermunt L, Hok-A-Hin YS, van Nee M, Chen-Plotkin A, Irwin DJ, Hu WT, Lah JJ, Seyfried NT, Dammer EB, Herradon G, Meeter LH, van Swieten J, et al. CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature Aging. 2: 1040-1053. PMID 37118088 DOI: 10.1038/s43587-022-00300-1  0.379
2022 Chan AWS, Cho IK, Li CX, Zhang X, Patel S, Rusnak R, Raper J, Bachevalier J, Moran SP, Chi T, Cannon KH, Hunter CE, Martin RC, Xiao H, Yang SH, ... ... Lah JJ, et al. Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey. Aging Brain. 2. PMID 36589695 DOI: 10.1016/j.nbas.2022.100044  0.335
2022 Hajjar I, Okafor M, Wan L, Yang Z, Nye JA, Bohsali A, Shaw LM, Levey AI, Lah JJ, Calhoun VD, Moore RH, Goldstein FC. Safety and biomarker effects of candesartan in non-hypertensive adults with prodromal Alzheimer's disease. Brain Communications. 4: fcac270. PMID 36440097 DOI: 10.1093/braincomms/fcac270  0.344
2022 Dammer EB, Ping L, Duong DM, Modeste ES, Seyfried NT, Lah JJ, Levey AI, Johnson ECB. Multi-platform proteomic analysis of Alzheimer's disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome. Alzheimer's Research & Therapy. 14: 174. PMID 36384809 DOI: 10.1186/s13195-022-01113-5  0.309
2022 Hone-Blanchet A, Bhosali A, Krishnamurthy LC, Shahid SS, Lin Q, Zhao L, Bisht AS, John SE, Loring D, Goldstein F, Levey A, Lah J, Qiu D, Crosson B. Frontal Metabolites and Alzheimer's Disease Biomarkers in Healthy Older Women and Women Diagnosed with Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 35431238 DOI: 10.3233/JAD-215431  0.325
2022 Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, ... ... Lah JJ, et al. Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature Neuroscience. 25: 213-225. PMID 35115731 DOI: 10.1038/s41593-021-00999-y  0.375
2021 Levey AI, Qiu D, Zhao L, Hu WT, Duong DM, Higginbotham L, Dammer EB, Seyfried NT, Wingo TS, Hales CM, Gámez Tansey M, Goldstein DS, Abrol A, Calhoun VD, Goldstein FC, ... ... Lah JJ, et al. A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment. Brain : a Journal of Neurology. PMID 34919634 DOI: 10.1093/brain/awab452  0.337
2021 Ngolab J, Donohue M, Belsha A, Salazar J, Cohen P, Jaiswal S, Tan V, Gessert D, Korouri S, Aggarwal NT, Alber J, Johnson K, Jicha G, van Dyck C, Lah J, et al. Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12199. PMID 34430703 DOI: 10.1002/dad2.12199  0.306
2021 Abreha MH, Ojelade S, Dammer EB, McEachin ZT, Duong DM, Gearing M, Bassell GJ, Lah JJ, Levey AI, Shulman JM, Seyfried NT. TBK1 interacts with tau and enhances neurodegeneration in tauopathy. The Journal of Biological Chemistry. 100760. PMID 33965374 DOI: 10.1016/j.jbc.2021.100760  0.313
2021 Guo Q, Dammer EB, Zhou M, Kundinger SR, Gearing M, Lah JJ, Levey AI, Shulman JM, Seyfried NT. Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 14: 623659. PMID 33815056 DOI: 10.3389/fnmol.2021.623659  0.306
2021 Wingo AP, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Robins C, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, et al. Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nature Genetics. PMID 33510477 DOI: 10.1038/s41588-020-00773-z  0.351
2021 Li HD, Funk CC, McFarland K, Dammer EB, Allen M, Carrasquillo MM, Levties Y, Chakrabarty P, Burgess JD, Wang X, Dickson D, Seyfried NT, Duong DM, Lah JJ, Younkin SG, et al. Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480174 DOI: 10.1002/alz.12254  0.342
2020 Higginbotham L, Ping L, Dammer EB, Duong DM, Zhou M, Gearing M, Hurst C, Glass JD, Factor SA, Johnson ECB, Hajjar I, Lah JJ, Levey AI, Seyfried NT. Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease. Science Advances. 6. PMID 33087358 DOI: 10.1126/sciadv.aaz9360  0.354
2020 Ping L, Kundinger SR, Duong DM, Yin L, Gearing M, Lah JJ, Levey AI, Seyfried NT. Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease. Scientific Data. 7: 315. PMID 32985496 DOI: 10.1038/s41597-020-00650-8  0.34
2020 Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P, Ma W, Wang YC, Jiang C, Audrain M, Comella PH, Fakira AK, Hariharan SP, Belbin GM, Girdhar K, ... ... Lah JJ, et al. Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. Nature Communications. 11: 3942. PMID 32770063 DOI: 10.1038/S41467-020-17405-Z  0.456
2020 Swarup V, Chang TS, Duong DM, Dammer EB, Dai J, Lah JJ, Johnson ECB, Seyfried NT, Levey AI, Geschwind DH. Identification of Conserved Proteomic Networks in Neurodegenerative Dementia. Cell Reports. 31: 107807. PMID 32579933 DOI: 10.1016/J.Celrep.2020.107807  0.457
2020 Wingo AP, Fan W, Duong DM, Gerasimov ES, Dammer EB, Liu Y, Harerimana NV, White B, Thambisetty M, Troncoso JC, Kim N, Schneider JA, Hajjar IM, Lah JJ, Bennett DA, et al. Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature Neuroscience. PMID 32576978 DOI: 10.1038/S41593-020-0662-2  0.383
2020 Zhou M, Haque RU, Dammer EB, Duong DM, Ping L, Johnson ECB, Lah JJ, Levey AI, Seyfried NT. Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease. Clinical Proteomics. 17: 19. PMID 32514259 DOI: 10.1186/S12014-020-09285-8  0.486
2020 Wingo AP, Fan W, Duong DM, Gerasimov ES, Dammer EB, Liu Y, Harerimana NV, White B, Thambisetty M, Troncoso JC, Kim N, Schneider JA, Hajjar IM, Lah JJ, Bennett DA, et al. Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature Neuroscience. PMID 32424284 DOI: 10.1038/S41593-020-0635-5  0.375
2020 Rayaprolu S, Gao T, Xiao H, Ramesha S, Weinstock LD, Shah J, Duong DM, Dammer EB, Webster JA, Lah JJ, Wood LB, Betarbet R, Levey AI, Seyfried NT, Rangaraju S. Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease. Molecular Neurodegeneration. 15: 28. PMID 32381088 DOI: 10.1186/S13024-020-00377-5  0.371
2020 Haque RU, Pongos AL, Manzaneres CM, Lah JJ, Levey AI, Clifford GD. Deep convolutional neural networks and transfer learning for measuring cognitive impairment using eye-tracking in a distributed tablet-based environment. Ieee Transactions On Bio-Medical Engineering. PMID 32340935 DOI: 10.1109/Tbme.2020.2990734  0.383
2020 Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, ... ... Lah JJ, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6  0.486
2020 Nocera JR, Gregory GJ, Lah JJ, Levey AI. A longitudinal study of gait on fall risk and disease progression in patients with mild cognitive impairment and Alzheimer's disease Alzheimer's & Dementia. 16. DOI: 10.1002/alz.043612  0.303
2020 Higginbotham LA, Ping L, Dammer EB, Duong D, Zhou M, Gearing M, Johnson EC, Hajjar I, Lah JJ, Levey AI, Seyfried NT. Proteomics identifies CSF biomarker panels reflective of pathological networks in the Alzheimer's disease brain Alzheimer's & Dementia. 16. DOI: 10.1002/alz.042227  0.315
2019 Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Reports. 29: 301-316.e10. PMID 31597093 DOI: 10.1016/J.Celrep.2019.08.104  0.449
2019 Higginbotham L, Dammer EB, Duong DM, Modeste E, Montine TJ, Lah JJ, Levey AI, Seyfried NT. Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease. Proteomes. 7. PMID 31461916 DOI: 10.3390/Proteomes7030030  0.402
2019 Goetz ME, Hanfelt JJ, John SE, Bergquist SH, Loring DW, Quyyumi A, Clifford GD, Vaccarino V, Goldstein F, Johnson Nd TM, Kuerston R, Marcus M, Levey AI, Lah JJ. Rationale and Design of the Emory Healthy Aging and Emory Healthy Brain Studies. Neuroepidemiology. 1-14. PMID 31454799 DOI: 10.1159/000501856  0.422
2019 Wingo TS, Cutler DJ, Wingo AP, Le NA, Rabinovici GD, Miller BL, Lah JJ, Levey AI. Association of Early-Onset Alzheimer Disease With Elevated Low-density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB. Jama Neurology. PMID 31135820 DOI: 10.1001/Jamaneurol.2019.0648  0.394
2019 Zhou M, Duong DM, Johnson ECB, Dai J, Lah JJ, Levey AI, Seyfried NT. Mass spectrometry-based quantification of Tau in human cerebrospinal fluid using a complementary tryptic peptide standard. Journal of Proteome Research. PMID 30983353 DOI: 10.1021/Acs.Jproteome.8B00920  0.321
2019 Wingo AP, Dammer EB, Breen MS, Logsdon BA, Duong DM, Troncosco JC, Thambisetty M, Beach TG, Serrano GE, Reiman EM, Caselli RJ, Lah JJ, Seyfried NT, Levey AI, Wingo TS. Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age. Nature Communications. 10: 1619. PMID 30962425 DOI: 10.1038/S41467-019-09613-Z  0.346
2019 Haque RU, Manzanares CM, Brown LN, Pongos AL, Lah JJ, Clifford GD, Levey AI. VisMET: a passive, efficient, and sensitive assessment of visuospatial memory in healthy aging, mild cognitive impairment, and Alzheimer's disease. Learning & Memory (Cold Spring Harbor, N.Y.). 26: 93-100. PMID 30770466 DOI: 10.1101/Lm.048124.118  0.347
2019 Gordon BA, Blazey TM, Christensen J, Dincer A, Flores S, Keefe S, Chen C, Su Y, McDade EM, Wang G, Li Y, Hassenstab J, Aschenbrenner A, Hornbeck R, Jack CR, ... ... Lah JJ, et al. Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers. Brain : a Journal of Neurology. PMID 30753379 DOI: 10.1093/Brain/Awz019  0.439
2019 Zhang TT, Dammer EB, Abreha M, Duong DM, Lah JJ, Levey AI, Seyfried NT. Proteomic analysis of the poly‐ubiquitin profiles in Alzheimer's Disease The Faseb Journal. 33. DOI: 10.1096/fasebj.2019.33.1_supplement.465.7  0.315
2019 Levey AI, Lah JJ, Hu WT, Wingo TS, Hales CM, Manzanares C, Tansey MG, Goldstein DS, Zhao L, Galasko DR, Edland SD, Hanfelt J, Weinshenker D. O4-11-05: A PROOF OF CONCEPT PHASE II STUDY REPURPOSING ATOMOXETINE FOR NEUROPROTECTION IN MILD COGNITIVE IMPAIRMENT: EVIDENCE FOR TARGET ENGAGEMENT, REGULATION OF CSF BIOMARKERS, AND DISEASE-MODIFYING POTENTIAL Alzheimer's & Dementia. 15: P1263-P1264. DOI: 10.1016/J.Jalz.2019.06.4804  0.336
2019 Ping L, Higginbotham LA, Dammer EB, Duong D, Zhou M, Wingo TS, Johnson EC, Lah JJ, Levey AI, Seyfried NT. INTEGRATIVE PROTEOMICS LINKS CEREBROSPINAL FLUID BIOMARKERS TO PATHOLOGICAL NETWORKS IN THE ALZHEIMER’S DISEASE BRAIN Alzheimer's & Dementia. 15: P191. DOI: 10.1016/J.Jalz.2019.06.4517  0.347
2019 Guo C, Hsieh Y, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, Jager PLD, Seyfried NT, Liu Z, Shulman JM. P4-130: Tau-Mediated Disruption Of The Spliceosome Triggers Cryptic Rna Splicing And Neurodegeneration In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3791  0.396
2019 Modeste ES, Dammer EB, Duong D, Lah JJ, Levey AI, Wingo AP, Wingo TS, Seyfried NT. P4-115: SEX-SPECIFIC PROTEIN DIFFERENCES LINKED TO ALZHEIMER'S DISEASE RISK UNCOVERED BY A COEXPRESSION-REGRESSION FRAMEWORK Alzheimer's & Dementia. 15: P1320-P1320. DOI: 10.1016/J.Jalz.2019.06.3776  0.406
2019 Wingo AP, Schneider JA, Breen MS, Seyfried NT, Yang H, Lah JJ, Levey AI, Jin P, Bennett DA, Jager PLD, Wingo TS. P4-107: Brain Micrornas Are Associated With Variation In Cognitive Trajectory In Advanced Age Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3768  0.322
2019 Wingo TS, Yang J, Canon SM, Logsdon BA, Seyfried NT, Lah JJ, Levey AI, Boyle PA, Schneider JA, Jager PLD, Bennett DA, Wingo AP. P3-151: Brain Micrornas Associated With Late-Life Depression Are Also Linked To Cognitive Trajectory And Dementia Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3180  0.337
2019 Lee TV, Allison KS, Ojelade SA, Lah JJ, Levey AI, Seyfried NT, Shulman JM. P3-126: FUNCTIONAL DISSECTION OF AN ALZHEIMER'S DISEASE SUSCEPTIBILITY GENE NETWORK Alzheimer's & Dementia. 15: P978-P979. DOI: 10.1016/J.Jalz.2019.06.3154  0.372
2019 Johnson ECB, Dammer EB, Duong D, Yin L, Thambisetty M, Troncoso JC, Lah JJ, Levey AI, Seyfried NT. P2-218: Deep Proteomic Network Analysis Of Alzheimer'S Disease Brain Reveals Alterations In Rna Binding Proteins And Rna Splicing Associated With Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2625  0.379
2018 Dai J, Johnson ECB, Dammer EB, Duong DM, Gearing M, Lah JJ, Levey AI, Wingo TS, Seyfried NT. Effects of Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 11: 454. PMID 30618606 DOI: 10.3389/Fnmol.2018.00454  0.418
2018 Swarup V, Hinz FI, Rexach JE, Noguchi KI, Toyoshiba H, Oda A, Hirai K, Sarkar A, Seyfried NT, Cheng C, Haggarty SJ, Grossman M, Van Deerlin VM, Trojanowski JQ, ... Lah JJ, et al. Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nature Medicine. PMID 30510257 DOI: 10.1038/S41591-018-0223-3  0.353
2018 Johnson ECB, Dammer EB, Duong DM, Yin L, Thambisetty M, Troncoso JC, Lah JJ, Levey AI, Seyfried NT. Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease. Molecular Neurodegeneration. 13: 52. PMID 30286791 DOI: 10.1186/S13024-018-0282-4  0.491
2018 Abreha MH, Dammer EB, Ping L, Zhang T, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease. Proteomics. e1800108. PMID 30230243 DOI: 10.1002/Pmic.201800108  0.469
2018 Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, ... ... Lah JJ, et al. The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease. Scientific Data. 5: 180185. PMID 30204156 DOI: 10.1038/Sdata.2018.185  0.44
2018 Rangaraju S, Dammer EB, Raza SA, Gao T, Xiao H, Betarbet R, Duong DM, Webster JA, Hales CM, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins. Molecular Neurodegeneration. 13: 34. PMID 29954413 DOI: 10.1186/S13024-018-0266-4  0.375
2018 Hanfelt JJ, Peng L, Goldstein FC, Lah JJ. Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center. Neurobiology of Disease. PMID 29859866 DOI: 10.1016/J.Nbd.2018.05.025  0.41
2018 Bishof I, Dammer EB, Duong DM, Kundinger S, Gearing M, Lah JJ, Levey AI, Seyfried NT. RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease. The Journal of Biological Chemistry. PMID 29802200 DOI: 10.1074/Jbc.Ra118.001747  0.355
2018 Rangaraju S, Dammer EB, Raza SA, Rathakrishnan P, Xiao H, Gao T, Duong DM, Pennington MW, Lah JJ, Seyfried NT, Levey AI. Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease. Molecular Neurodegeneration. 13: 24. PMID 29784049 DOI: 10.1186/S13024-018-0254-8  0.444
2018 Rangaraju S, Raza SA, Li NX, Betarbet R, Dammer EB, Duong D, Lah JJ, Seyfried NT, Levey AI. Differential Phagocytic Properties of CD45Microglia and CD45Brain Mononuclear Phagocytes-Activation and Age-Related Effects. Frontiers in Immunology. 9: 405. PMID 29552013 DOI: 10.3389/Fimmu.2018.00405  0.434
2018 Ping L, Duong DM, Yin L, Gearing M, Lah JJ, Levey AI, Seyfried NT. Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease. Scientific Data. 5: 180036. PMID 29533394 DOI: 10.1038/Sdata.2018.36  0.428
2017 Umoh ME, Dammer EB, Dai J, Duong DM, Lah JJ, Levey AI, Gearing M, Glass JD, Seyfried NT. A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain. Embo Molecular Medicine. PMID 29191947 DOI: 10.15252/Emmm.201708202  0.353
2017 Cherry JD, Zeineddin A, Dammer EB, Webster JA, Duong D, Seyfried NT, Levey AI, Alvarez VE, Huber BR, Stein TD, Kiernan PT, McKee AC, Lah JJ, Hales CM. Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy. Journal of Neuropathology and Experimental Neurology. PMID 29145658 DOI: 10.1093/Jnen/Nlx100  0.467
2017 Chalermpalanupap T, Schroeder JP, Rorabaugh JM, Liles LC, Lah JJ, Levey AI, Weinshenker D. Locus coeruleus ablation exacerbates cognitive deficits, neuropathology, and lethality in P301S tau transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29133432 DOI: 10.1523/Jneurosci.1483-17.2017  0.456
2017 McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, et al. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Molecular Neurodegeneration. 12: 82. PMID 29110684 DOI: 10.1186/S13024-017-0219-3  0.396
2017 Allen M, Wang X, Burgess JD, Watzlawik J, Serie DJ, Younkin CS, Nguyen T, Malphrus KG, Lincoln S, Carrasquillo MM, Ho C, Chakrabarty P, Strickland S, Murray ME, Swarup V, ... ... Lah JJ, et al. Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29107053 DOI: 10.1016/J.Jalz.2017.09.012  0.467
2017 An Y, Varma VR, Varma S, Casanova R, Dammer E, Pletnikova O, Chia CW, Egan JM, Ferrucci L, Troncoso J, Levey A, Lah J, Seyfried N, Legido-Quigley C, O'Brien R, et al. Evidence for brain glucose dysregulation in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29055815 DOI: 10.1016/J.Jalz.2017.09.011  0.424
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Lah JJ, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.384
2017 Wingo TS, Duong DM, Zhou M, Dammer EB, Wu H, Cutler DJ, Lah JJ, Levey AI, Seyfried NT. Integrating Next-Generation Genomic Sequencing and Mass Spectrometry to Estimate Allele-Specific Protein Abundance in Human Brain. Journal of Proteome Research. PMID 28691493 DOI: 10.1021/Acs.Jproteome.7B00324  0.309
2017 Seyfried NT, Dammer EB, Duong DM, Deng Q, Troncoso JC, Thambisetty M, Lah JJ, Levey AI. PROTEIN CO-EXPRESSION NETWORK ANALYSIS IN ASYMPTOMATIC AND SYMPTOMATIC ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P554-P555. DOI: 10.1016/J.Jalz.2017.07.155  0.406
2016 Seyfried NT, Dammer EB, Swarup V, Nandakumar D, Duong DM, Yin L, Deng Q, Nguyen T, Hales CM, Wingo T, Glass J, Gearing M, Thambisetty M, Troncoso JC, Geschwind DH, ... Lah JJ, et al. A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease. Cell Systems. PMID 27989508 DOI: 10.1016/J.Cels.2016.11.006  0.453
2016 Varma VR, Varma S, An Y, Hohman TJ, Seddighi S, Casanova R, Beri A, Dammer EB, Seyfried NT, Pletnikova O, Moghekar A, Wilson MR, Lah JJ, O'Brien RJ, Levey AI, et al. Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway. Molecular Psychiatry. PMID 27872486 DOI: 10.1038/Mp.2016.206  0.463
2016 Hales CM, Dammer EB, Deng Q, Duong DM, Gearing M, Troncoso JC, Thambisetty M, Lah JJ, Shulman JM, Levey AI, Seyfried NT. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. PMID 27718298 DOI: 10.1002/Pmic.201600057  0.476
2016 Agca C, Klakotskaia D, Schachtman TR, Chan AW, Lah JJ, Agca Y. Presenilin 1 transgene addition to amyloid precursor protein overexpressing transgenic rats increases amyloid beta 42 levels and results in loss of memory retention. Bmc Neuroscience. 17: 46. PMID 27388605 DOI: 10.1186/S12868-016-0281-8  0.36
2016 Loring DW, Goldstein FC, Chen C, Drane DL, Lah JJ, Zhao L, Larrabee GJ. False-Positive Error Rates for Reliable Digit Span and Auditory Verbal Learning Test Performance Validity Measures in Amnestic Mild Cognitive Impairment and Early Alzheimer Disease. Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists. PMID 27084732 DOI: 10.1093/Arclin/Acw014  0.363
2016 Bernstein AI, Lin Y, Street RC, Lin L, Dai Q, Yu L, Bao H, Gearing M, Lah JJ, Nelson PT, He C, Levey AI, Mullé JG, Duan R, Jin P. 5-hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity. Human Molecular Genetics. PMID 27060332 DOI: 10.1093/Hmg/Ddw109  0.448
2016 Hu WT, Watts KD, Tailor P, Nguyen TP, Howell JC, Lee RC, Seyfried NT, Gearing M, Hales CM, Levey AI, Lah JJ, Lee EK. CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease. Acta Neuropathologica Communications. 4: 14. PMID 26887322 DOI: 10.1186/S40478-016-0277-8  0.456
2016 Seyfried NT, Ping L, Dammer EB, Duong DM, Gearing M, Deng Q, Lah JJ, Levey AI. O5-06-02: Proteomic Network Analysis to Find Common Mechanisms Underlying Alzheimer's Disease and PD Alzheimer's & Dementia. 12: P390-P391. DOI: 10.1016/J.Jalz.2016.06.736  0.342
2016 Levey AI, Dammer EB, Duong DM, Lah JJ, Seyfried NT. Discovery Of Novel Proteomic Targets For Treatment Of Alzheimer'S Disease Alzheimers & Dementia. 12: 215. DOI: 10.1016/J.Jalz.2016.06.382  0.383
2016 Chalermpalanupap T, Bradner J, Chen T, Jerome C, Schroeder J, Lah JJ, Tansey MG, Levey AI, Weinshenker D. P3-069: Elucidating the Relationship Between Hyperphosphorylated TAU and Locus Coeruleus Degeneration in Alzheimer’s Disease Alzheimer's & Dementia. 12: P844-P844. DOI: 10.1016/J.Jalz.2016.06.1727  0.366
2016 Varma VR, Varma S, An Y, Beri A, Dammer EB, Seyfried NT, Moghekar A, Wilson M, Lah JJ, O’Brien R, Levey AI, Troncoso JC, Albert MS, Thambisetty M. The Acute Phase Protein Alpha-2-Macroglobulin Predicts Risk Of Incident Alzheimer'S Disease And Modulates Tau Pathology Through The Rcan1-Calcineurin Pathway Alzheimers & Dementia. 12: 745. DOI: 10.1016/J.Jalz.2016.06.1554  0.368
2015 Steinberg S, Stefansson H, Jonsson T, Johannsdottir H, Ingason A, Helgason H, Sulem P, Magnusson OT, Gudjonsson SA, Unnsteinsdottir U, Kong A, Helisalmi S, Soininen H, Lah JJ, et al. Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease. Nature Genetics. 47: 445-7. PMID 25807283 DOI: 10.1038/Ng.3246  0.402
2015 Hu WT, Watts KD, Shaw LM, Howell JC, Trojanowski JQ, Basra S, Glass JD, Lah JJ, Levey AI. CSF beta-amyloid 1-42 - what are we measuring in Alzheimer's disease? Annals of Clinical and Translational Neurology. 2: 131-9. PMID 25750918 DOI: 10.1002/Acn3.160  0.397
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Lah JJ, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.446
2015 Dammer EB, Lee AK, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins. Proteomics. 15: 508-19. PMID 25332170 DOI: 10.1002/Pmic.201400189  0.432
2015 Dammer EB, Ren R, Duong DM, Lee AK, Gearing M, Lah JJ, Levey AI, Seyfried NT. O4-12-03: Brain phosphoproteome network analysis discriminates Alzheimer's disease from other tauopathies Alzheimer's & Dementia. 11: P300-P300. DOI: 10.1016/J.Jalz.2015.07.415  0.386
2015 Dammer EB, Duong DM, Yin L, Swarup V, Parikshak N, Coppola G, Geschwind DH, Troncoso JC, Thambisetty M, Seyfried NT, Lah JJ, Levey AI. O4-12-02: Protein co-expression network analysis in Alzheimer's disease Alzheimer's & Dementia. 11: P299-P299. DOI: 10.1016/J.Jalz.2015.07.414  0.381
2014 Hales C, Neill S, Gearing M, Cooper D, Glass J, Lah J. Late-stage CTE pathology in a retired soccer player with dementia. Neurology. 83: 2307-9. PMID 25378682 DOI: 10.1212/Wnl.0000000000001081  0.35
2014 Diner I, Hales CM, Bishof I, Rabenold L, Duong DM, Yi H, Laur O, Gearing M, Troncoso J, Thambisetty M, Lah JJ, Levey AI, Seyfried NT. Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease. The Journal of Biological Chemistry. 289: 35296-313. PMID 25355317 DOI: 10.1074/Jbc.M114.562959  0.342
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Lah JJ, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.353
2014 Bai B, Chen PC, Hales CM, Wu Z, Pagala V, High AA, Levey AI, Lah JJ, Peng J. Integrated approaches for analyzing U1-70K cleavage in Alzheimer's disease. Journal of Proteome Research. 13: 4526-34. PMID 24902715 DOI: 10.1021/Pr5003593  0.329
2014 Hales CM, Seyfried NT, Dammer EB, Duong D, Yi H, Gearing M, Troncoso JC, Mufson EJ, Thambisetty M, Levey AI, Lah JJ. U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21. Molecular Neurodegeneration. 9: 15. PMID 24773620 DOI: 10.1186/1750-1326-9-15  0.416
2014 Hales CM, Dammer EB, Diner I, Yi H, Seyfried NT, Gearing M, Glass JD, Montine TJ, Levey AI, Lah JJ. Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 24: 344-51. PMID 24571648 DOI: 10.1111/Bpa.12133  0.434
2014 Steenland K, Zhao L, Goldstein F, Cellar J, Lah J. Biomarkers for predicting cognitive decline in those with normal cognition. Journal of Alzheimer's Disease : Jad. 40: 587-94. PMID 24496071 DOI: 10.3233/Jad-2014-131343  0.424
2013 Herskowitz JH, Feng Y, Mattheyses AL, Hales CM, Higginbotham LA, Duong DM, Montine TJ, Troncoso JC, Thambisetty M, Seyfried NT, Levey AI, Lah JJ. Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19086-98. PMID 24305806 DOI: 10.1523/Jneurosci.2508-13.2013  0.459
2013 Hu WT, Watts K, Grossman M, Glass J, Lah JJ, Hales C, Shelnutt M, Van Deerlin V, Trojanowski JQ, Levey AI. Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP. Neurology. 81: 1945-52. PMID 24174584 DOI: 10.1212/01.Wnl.0000436625.63650.27  0.358
2013 Hales CM, Rees H, Seyfried NT, Dammer EB, Duong DM, Gearing M, Montine TJ, Troncoso JC, Thambisetty M, Levey AI, Lah JJ, Wingo TS. Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes. Journal of Neuropathology and Experimental Neurology. 72: 1009-15. PMID 24128675 DOI: 10.1097/01.Jnen.0000435847.59828.Db  0.469
2013 Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, ... ... Lah JJ, et al. U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 16562-7. PMID 24023061 DOI: 10.1073/Pnas.1310249110  0.476
2013 Donovan LE, Dammer EB, Duong DM, Hanfelt JJ, Levey AI, Seyfried NT, Lah JJ. Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease. Alzheimer's Research & Therapy. 5: 32. PMID 23764030 DOI: 10.1186/Alzrt186  0.397
2013 Zhou J, Jones DR, Duong DM, Levey AI, Lah JJ, Peng J. Proteomic analysis of postsynaptic density in Alzheimer's disease. Clinica Chimica Acta; International Journal of Clinical Chemistry. 420: 62-8. PMID 23537733 DOI: 10.1016/J.Cca.2013.03.016  0.342
2013 Zola SM, Manzanares CM, Clopton P, Lah JJ, Levey AI. A behavioral task predicts conversion to mild cognitive impairment and Alzheimer's disease. American Journal of Alzheimer's Disease and Other Dementias. 28: 179-84. PMID 23271330 DOI: 10.1177/1533317512470484  0.411
2013 Jonsson T, Stefansson H, Steinberg S, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, et al. Variant of TREM2 associated with the risk of Alzheimer's disease. The New England Journal of Medicine. 368: 107-16. PMID 23150908 DOI: 10.1056/Nejmoa1211103  0.442
2013 Higginbotham L, Donovan L, Duong D, Dammer E, Schantz A, Montine T, Lah J, Levey A, Seyfried N. O2-08-06: Analysis of the synapse-rich brain proteome reveals potential markers of asymptomatic Alzheimer's disease Alzheimer's & Dementia. 9: P331-P331. DOI: 10.1016/J.Jalz.2013.04.182  0.39
2013 Herskowitz J, Feng Y, Higginbotham L, Seyfried N, Levey A, Lah J. Selective drug inhibition of rho kinase II (ROCK2) reduces beta-amyloid production in the brain Alzheimers & Dementia. 9: 153. DOI: 10.1016/J.Jalz.2013.04.115  0.329
2012 Mufson EJ, He B, Nadeem M, Perez SE, Counts SE, Leurgans S, Fritz J, Lah J, Ginsberg SD, Wuu J, Scheff SW. Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 71: 1018-29. PMID 23095849 DOI: 10.1097/Nen.0B013E318272Caab  0.449
2012 Sager KL, Wuu J, Herskowitz JH, Mufson EJ, Levey AI, Lah JJ. Neuronal LR11 expression does not differentiate between clinically-defined Alzheimer's disease and control brains. Plos One. 7: e40527. PMID 22927900 DOI: 10.1371/Journal.Pone.0040527  0.472
2012 Dammer EB, Fallini C, Gozal YM, Duong DM, Rossoll W, Xu P, Lah JJ, Levey AI, Peng J, Bassell GJ, Seyfried NT. Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination. Plos One. 7: e38658. PMID 22761693 DOI: 10.1371/Journal.Pone.0038658  0.335
2012 Herskowitz JH, Gozal YM, Duong DM, Dammer EB, Gearing M, Ye K, Lah JJ, Peng J, Levey AI, Seyfried NT. Asparaginyl endopeptidase cleaves TDP-43 in brain. Proteomics. 12: 2455-63. PMID 22718532 DOI: 10.1002/Pmic.201200006  0.354
2012 Herskowitz JH, Offe K, Deshpande A, Kahn RA, Levey AI, Lah JJ. GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production. Molecular Biology of the Cell. 23: 2645-57. PMID 22621900 DOI: 10.1091/Mbc.E12-01-0014  0.413
2012 Donovan LE, Higginbotham L, Dammer EB, Gearing M, Rees HD, Xia Q, Duong DM, Seyfried NT, Lah JJ, Levey AI. Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease. Proteomics. Clinical Applications. 6: 201-11. PMID 22532456 DOI: 10.1002/Prca.201100068  0.443
2012 Seyfried NT, Gozal YM, Donovan LE, Herskowitz JH, Dammer EB, Xia Q, Ku L, Chang J, Duong DM, Rees HD, Cooper DS, Glass JD, Gearing M, Tansey MG, Lah JJ, et al. Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards. Journal of Proteome Research. 11: 2721-38. PMID 22416763 DOI: 10.1021/Pr2010814  0.382
2012 Yamout K, Goldstein FC, Lah JJ, Levey AI, Bliwise DL. Neurocognitive correlates of nocturnal oxygen desaturation in a memory clinic population. Journal of Clinical and Experimental Neuropsychology. 34: 325-32. PMID 22233185 DOI: 10.1080/13803395.2011.642849  0.316
2012 Rosen RF, Fritz JJ, Dooyema J, Cintron AF, Hamaguchi T, Lah JJ, LeVine H, Jucker M, Walker LC. Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats. Journal of Neurochemistry. 120: 660-6. PMID 22017494 DOI: 10.1111/J.1471-4159.2011.07551.X  0.342
2012 Wingo TS, Lah JJ, Levey AI, Cutler DJ. Autosomal recessive causes likely in early-onset Alzheimer disease. Archives of Neurology. 69: 59-64. PMID 21911656 DOI: 10.1001/Archneurol.2011.221  0.412
2012 Wingo TS, Rosen A, Cutler DJ, Lah JJ, Levey AI. Paraoxonase-1 polymorphisms in Alzheimer's disease, Parkinson's disease, and AD-PD spectrum diseases. Neurobiology of Aging. 33: 204.e13-5. PMID 20947215 DOI: 10.1016/J.Neurobiolaging.2010.08.010  0.373
2011 Gozal YM, Seyfried NT, Gearing M, Glass JD, Heilman CJ, Wuu J, Duong DM, Cheng D, Xia Q, Rees HD, Fritz JJ, Cooper DS, Peng J, Levey AI, Lah JJ. Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration. Molecular Neurodegeneration. 6: 82. PMID 22126117 DOI: 10.1186/1750-1326-6-82  0.416
2011 Hanfelt JJ, Wuu J, Sollinger AB, Greenaway MC, Lah JJ, Levey AI, Goldstein FC. An exploration of subgroups of mild cognitive impairment based on cognitive, neuropsychiatric and functional features: analysis of data from the National Alzheimer's Coordinating Center. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 19: 940-50. PMID 22024618 DOI: 10.1097/Jgp.0B013E31820Ee9D2  0.359
2011 Gozal YM, Dammer EB, Duong DM, Cheng D, Gearing M, Rees HD, Peng J, Lah JJ, Levey AI. Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology. Frontiers in Neurology. 2: 24. PMID 21577247 DOI: 10.3389/Fneur.2011.00024  0.373
2011 Dammer EB, Na CH, Xu P, Seyfried NT, Duong DM, Cheng D, Gearing M, Rees H, Lah JJ, Levey AI, Rush J, Peng J. Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease. The Journal of Biological Chemistry. 286: 10457-65. PMID 21278249 DOI: 10.1074/Jbc.M110.149633  0.348
2011 Wang L, Goldstein FC, Levey AI, Lah JJ, Meltzer CC, Holder CA, Mao H. White matter hyperintensities and changes in white matter integrity in patients with Alzheimer's disease. Neuroradiology. 53: 373-81. PMID 21152911 DOI: 10.1007/S00234-010-0806-2  0.387
2011 Herskowitz JH, Seyfried NT, Gearing M, Kahn RA, Peng J, Levey AI, Lah JJ. Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production. The Journal of Biological Chemistry. 286: 6117-27. PMID 21147781 DOI: 10.1074/Jbc.M110.167239  0.347
2011 Wingo T, Levey A, Lah J, Cutler D. Early-onset Alzheimer's disease likely has autosomal recessive causes Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.088  0.414
2011 Zola S, Manzanares C, Levey A, Lah J. P3-109: Predicting the onset of Alzheimer's disease with a behavioral task Alzheimer's & Dementia. 7: S549-S549. DOI: 10.1016/J.Jalz.2011.05.1549  0.349
2010 Vieira SI, Rebelo S, Esselmann H, Wiltfang J, Lah J, Lane R, Small SA, Gandy S, da Cruz E Silva EF, da Cruz E Silva OA. Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated. Molecular Neurodegeneration. 5: 40. PMID 20937087 DOI: 10.1186/1750-1326-5-40  0.434
2010 Herskowitz JH, Seyfried NT, Duong DM, Xia Q, Rees HD, Gearing M, Peng J, Lah JJ, Levey AI. Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration. Journal of Proteome Research. 9: 6368-79. PMID 20886841 DOI: 10.1021/Pr100666C  0.386
2010 Gandy S, Simon AJ, Steele JW, Lublin AL, Lah JJ, Walker LC, Levey AI, Krafft GA, Levy E, Checler F, Glabe C, Bilker WB, Abel T, Schmeidler J, Ehrlich ME. Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers. Annals of Neurology. 68: 220-30. PMID 20641005 DOI: 10.1002/Ana.22052  0.372
2010 Steenland K, MacNeil J, Bartell S, Lah J. Analyses of diagnostic patterns at 30 alzheimer's disease centers in the US Neuroepidemiology. 35: 19-27. PMID 20357515 DOI: 10.1159/000302844  0.371
2010 Davis AA, Fritz JJ, Wess J, Lah JJ, Levey AI. Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4190-6. PMID 20335454 DOI: 10.1523/Jneurosci.6393-09.2010  0.387
2010 Seyfried NT, Gozal YM, Dammer EB, Xia Q, Duong DM, Cheng D, Lah JJ, Levey AI, Peng J. Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyubiquitin chains. Molecular & Cellular Proteomics : McP. 9: 705-18. PMID 20047951 DOI: 10.1074/Mcp.M800390-Mcp200  0.376
2010 Sollinger AB, Goldstein FC, Lah JJ, Levey AI, Factor SA. Mild cognitive impairment in Parkinson's disease: subtypes and motor characteristics. Parkinsonism & Related Disorders. 16: 177-80. PMID 19939721 DOI: 10.1016/J.Parkreldis.2009.11.002  0.356
2010 Perez SE, Berg BM, Moore KA, He B, Counts SE, Fritz JJ, Hu YS, Lazarov O, Lah JJ, Mufson EJ. DHA diet reduces AD pathology in young APPswe/PS1 Delta E9 transgenic mice: possible gender effects. Journal of Neuroscience Research. 88: 1026-40. PMID 19859965 DOI: 10.1002/Jnr.22266  0.315
2010 Lamar M, Libon DJ, Ashley AV, Lah JJ, Levey AI, Goldstein FC. The impact of vascular comorbidities on qualitative error analysis of executive impairment in Alzheimer's disease. Journal of the International Neuropsychological Society : Jins. 16: 77-83. PMID 19835657 DOI: 10.1017/S1355617709990981  0.391
2010 Rosen RF, Ciliax BJ, Wingo TS, Gearing M, Dooyema J, Lah JJ, Ghiso JA, LeVine H, Walker LC. Deficient high-affinity binding of Pittsburgh compound B in a case of Alzheimer's disease. Acta Neuropathologica. 119: 221-33. PMID 19690877 DOI: 10.1007/S00401-009-0583-3  0.423
2010 Lane RF, Raines SM, Levey A, Lah JJ, Small SA, Tanzi RE, Attie AD, Gandy SE. Diabetes-linked SORCS1, a gamma-secretase substrate and regulator of Alzheimer APP metabolism, forms complexes with multiple Alzheimer-linked proteins (APP, PS1, BACE, VPS35, and SORLA) Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.814  0.369
2010 Steele JW, Simon AJ, Lublin AL, Lah JJ, Walker LC, Levey AI, Krafft GA, Levy E, Glabe C, Bilker W, Abel T, Schmeidler J, Ehrlich ME, Gandy S. Evidence for dose-dependent neurotoxicity of amyloid-β oligomers/Aβ-derived diffusible ligands generated from physiological processing of transgenic human APP in situ in mouse brain Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.737  0.32
2009 Shirey JK, Brady AE, Jones PJ, Davis AA, Bridges TM, Kennedy JP, Jadhav SB, Menon UN, Xiang Z, Watson ML, Christian EP, Doherty JJ, Quirk MC, Snyder DH, Lah JJ, et al. A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14271-86. PMID 19906975 DOI: 10.1523/Jneurosci.3930-09.2009  0.317
2009 Gozal YM, Duong DM, Gearing M, Cheng D, Hanfelt JJ, Funderburk C, Peng J, Lah JJ, Levey AI. Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease. Journal of Proteome Research. 8: 5069-79. PMID 19746990 DOI: 10.1021/Pr900474T  0.48
2009 Mount DL, Ashley AV, Lah JJ, Levey AI, Goldstein FC. Is ApoE epsilon4 associated with cognitive functioning in African Americans diagnosed with Alzheimer Disease? An exploratory study. Southern Medical Journal. 102: 890-3. PMID 19668025 DOI: 10.1097/Smj.0B013E3181B21B82  0.436
2009 Wang L, Goldstein FC, Veledar E, Levey AI, Lah JJ, Meltzer CC, Holder CA, Mao H. Alterations in cortical thickness and white matter integrity in mild cognitive impairment measured by whole-brain cortical thickness mapping and diffusion tensor imaging. Ajnr. American Journal of Neuroradiology. 30: 893-9. PMID 19279272 DOI: 10.3174/Ajnr.A1484  0.309
2009 Crutcher MD, Calhoun-Haney R, Manzanares CM, Lah JJ, Levey AI, Zola SM. Eye tracking during a visual paired comparison task as a predictor of early dementia. American Journal of Alzheimer's Disease and Other Dementias. 24: 258-66. PMID 19246573 DOI: 10.1177/1533317509332093  0.342
2008 Goldstein FC, Ashley AV, Endeshaw YW, Hanfelt J, Lah JJ, Levey AI. Effects of hypertension and hypercholesterolemia on cognitive functioning in patients with alzheimer disease. Alzheimer Disease and Associated Disorders. 22: 336-42. PMID 19068499 DOI: 10.1097/Wad.0B013E318188E80D  0.43
2008 Dodson SE, Andersen OM, Karmali V, Fritz JJ, Cheng D, Peng J, Levey AI, Willnow TE, Lah JJ. Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12877-86. PMID 19036982 DOI: 10.1523/Jneurosci.4582-08.2008  0.481
2008 Steenland NK, Auman CM, Patel PM, Bartell SM, Goldstein FC, Levey AI, Lah JJ. Development of a rapid screening instrument for mild cognitive impairment and undiagnosed dementia. Journal of Alzheimer's Disease : Jad. 15: 419-27. PMID 18997295 DOI: 10.3233/Jad-2008-15308  0.367
2008 Li L, Cao D, Desmond R, Rahman A, Lah JJ, Levey AI, Zamrini E. Cognitive performance and plasma levels of homocysteine, vitamin B12, folate and lipids in patients with Alzheimer disease. Dementia and Geriatric Cognitive Disorders. 26: 384-90. PMID 18931498 DOI: 10.1159/000164271  0.317
2008 Jones CK, Brady AE, Davis AA, Xiang Z, Bubser M, Tantawy MN, Kane AS, Bridges TM, Kennedy JP, Bradley SR, Peterson TE, Ansari MS, Baldwin RM, Kessler RM, Deutch AY, ... Lah JJ, et al. Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10422-33. PMID 18842902 DOI: 10.1523/Jneurosci.1850-08.2008  0.302
2008 Betarbet R, Anderson LR, Gearing M, Hodges TR, Fritz JJ, Lah JJ, Levey AI. Fas-associated factor 1 and Parkinson's disease. Neurobiology of Disease. 31: 309-15. PMID 18573343 DOI: 10.1016/J.Nbd.2008.05.006  0.309
2008 Xia Q, Cheng D, Duong DM, Gearing M, Lah JJ, Levey AI, Peng J. Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry. Journal of Proteome Research. 7: 2845-51. PMID 18510355 DOI: 10.1021/Pr8000496  0.396
2008 Xia Q, Liao L, Cheng D, Duong DM, Gearing M, Lah JJ, Levey AI, Peng J. Proteomic identification of novel proteins associated with Lewy bodies. Frontiers in Bioscience : a Journal and Virtual Library. 13: 3850-6. PMID 18508479 DOI: 10.2741/2973  0.321
2008 Agca C, Fritz JJ, Walker LC, Levey AI, Chan AW, Lah JJ, Agca Y. Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically. Bmc Neuroscience. 9: 28. PMID 18302776 DOI: 10.1186/1471-2202-9-28  0.384
2008 Shrivastava-Ranjan P, Faundez V, Fang G, Rees H, Lah JJ, Levey AI, Kahn RA. Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network. Molecular Biology of the Cell. 19: 51-64. PMID 17959829 DOI: 10.1091/Mbc.E07-05-0465  0.375
2008 Simon ES, Dwolatzky T, Goldstein F, Doniger GM, Levey AI, Lah J, Friger M. P1-170: Non-verbal memory performance is associated with conversion to dementia within one year: A prospective study of mild cognitive impairment using computerized cognitive assessment Alzheimer's & Dementia. 4: T258-T258. DOI: 10.1016/J.Jalz.2008.05.758  0.327
2007 Anderson LR, Betarbet R, Gearing M, Gulcher J, Hicks AA, Stefánsson K, Lah JJ, Levey AI. PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain. Journal of Neuropathology and Experimental Neurology. 66: 955-64. PMID 17917589 DOI: 10.1097/Nen.0B013E3181567F17  0.305
2007 Rosen AR, Steenland NK, Hanfelt J, Factor SA, Lah JJ, Levey AI. Evidence of shared risk for Alzheimer's disease and Parkinson's disease using family history. Neurogenetics. 8: 263-70. PMID 17805588 DOI: 10.1007/S10048-007-0100-6  0.335
2007 Sager KL, Wuu J, Leurgans SE, Rees HD, Gearing M, Mufson EJ, Levey AI, Lah JJ. Neuronal LR11/sorLA expression is reduced in mild cognitive impairment. Annals of Neurology. 62: 640-7. PMID 17721864 DOI: 10.1002/Ana.21190  0.453
2007 Lee JH, Bliwise DL, Ansari FP, Goldstein FC, Cellar JS, Lah JJ, Levey AI. Daytime sleepiness and functional impairment in Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 15: 620-6. PMID 17586786 DOI: 10.1097/Jgp.0B013E3180381521  0.385
2006 Gozal YM, Cheng D, Duong DM, Lah JJ, Levey AI, Peng J. Merger of laser capture microdissection and mass spectrometry: a window into the amyloid plaque proteome. Methods in Enzymology. 412: 77-93. PMID 17046653 DOI: 10.1016/S0076-6879(06)12006-6  0.355
2006 Levey A, Lah J, Goldstein F, Steenland K, Bliwise D. Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's disease. Clinical Therapeutics. 28: 991-1001. PMID 16990077 DOI: 10.1016/J.Clinthera.2006.07.006  0.441
2006 Dodson SE, Gearing M, Lippa CF, Montine TJ, Levey AI, Lah JJ. LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 866-72. PMID 16957580 DOI: 10.1097/01.Jnen.0000228205.19915.20  0.465
2006 Nyborg AC, Ladd TB, Zwizinski CW, Lah JJ, Golde TE. Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel gamma-secretase substrates. Molecular Neurodegeneration. 1: 3. PMID 16930450 DOI: 10.1186/1750-1326-1-3  0.326
2006 Offe K, Dodson SE, Shoemaker JT, Fritz JJ, Gearing M, Levey AI, Lah JJ. The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1596-603. PMID 16452683 DOI: 10.1523/Jneurosci.4946-05.2006  0.451
2006 Ping L, Duong D, Dammer EB, Gearing M, Lah JJ, Levey AI, Seyfried NT. P2-217: INTEGRATED PROTEOMICS AND PHOSPHOPROTEOMICS REVEAL NETWORKS LINKED TO ALZHEIMER'S DISEASE RISK Alzheimer's & Dementia. 14: P752-P752. DOI: 10.1016/J.Jalz.2018.06.905  0.381
2006 Lee TV, Allison KS, Ojelade SA, Giagtzoglou N, Lah JJ, Levey AI, Seyfried NT, Shulman JM. O4-01-05: FUNCTIONAL GENETIC DISSECTION OF AN ALZHEIMER'S DISEASE SUSCEPTIBILITY NETWORK Alzheimer's & Dementia. 14: P1401-P1401. DOI: 10.1016/J.Jalz.2018.06.2913  0.349
2006 Chalermpalanupap T, Rorabaugh JM, DePuy SD, Rasmussen K, Lah JJ, Levey AI, Cohen RM, Weinshenker D. F4-07-04: THE CONSEQUENCES OF TAU IN THE LOCUS COERULEUS ON ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1394-P1394. DOI: 10.1016/J.Jalz.2018.06.2891  0.385
2006 Bishof IJ, Dammer EB, Duong D, Gearing M, Lah JJ, Levey AI, Seyfried NT. O2-02-05: RNA-BINDING PROTEINS WITH MIXED CHARGE DOMAINS SELF-ASSEMBLE AND AGGREGATE IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P612-P612. DOI: 10.1016/J.Jalz.2018.06.2649  0.326
2006 Raza SA, Gao T, Dammer EB, Xiao H, Lah JJ, Seyfried NT, Levey AI, Rangaraju S. O2-01-01: A TRANSCRIPTOMIC LANDSCAPE OF MICROGLIAL ACTIVATION IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P608-P608. DOI: 10.1016/J.Jalz.2018.06.2639  0.373
2006 Abreha M, Dammer EB, Ping L, Duong D, Lah JJ, Levey AI, Seyfried NT. P3-191: COMPREHENSIVE MAPPING OF ALZHEIMER'S DISEASE BRAIN UBIQUITYLOME Alzheimer's & Dementia. 14: P1140-P1140. DOI: 10.1016/J.Jalz.2018.06.1549  0.394
2006 Walker LC, Rosen R, Rees H, Stephens S, Carter S, Fritz J, Chan A, Bogush A, Gandy S, Ehrlich M, Levey A, Smith Y, Lah J. AbstractPoster presentation: Sunday posterP1-017: Focal lentivirus-mediated expression of transgenic tau and APP Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.392  0.324
2006 Lamar M, Goldstein F, Libon DJ, Ashley AV, Lah JJ, Levey AI. P3-055: The role of specific vascular biomarkers on executive functioning in Alzheimer's disease Alzheimer's & Dementia. 2: S388-S388. DOI: 10.1016/J.Jalz.2006.05.1322  0.396
2006 Simon ES, Goldstein FC, Dwolatzky T, Levey AI, Lah JJ, Doniger GM. P2-181: A prospective study of cognitive performance in amnestic MCI using comprehensive computerized assessment Alzheimer's & Dementia. 2: S288-S288. DOI: 10.1016/J.Jalz.2006.05.1019  0.309
2005 Goldstein FC, Ashley AV, Freedman LJ, Penix L, Lah JJ, Hanfelt J, Levey AI. Hypertension and cognitive performance in African Americans with Alzheimer disease. Neurology. 64: 899-901. PMID 15753433 DOI: 10.1212/01.Wnl.0000152888.26576.37  0.354
2004 Scherzer CR, Offe K, Gearing M, Rees HD, Fang G, Heilman CJ, Schaller C, Bujo H, Levey AI, Lah JJ. Loss of apolipoprotein E receptor LR11 in Alzheimer disease. Archives of Neurology. 61: 1200-5. PMID 15313836 DOI: 10.1001/Archneur.61.8.1200  0.432
2004 Liao L, Cheng D, Wang J, Duong DM, Losik TG, Gearing M, Rees HD, Lah JJ, Levey AI, Peng J. Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection. The Journal of Biological Chemistry. 279: 37061-8. PMID 15220353 DOI: 10.1074/Jbc.M403672200  0.468
2004 Dodson SE, Offe K, Carter SC, Shoemaker JT, Fang G, Lah JJ, Levey AI. P3-303 Examining the role of the APOE receptor LR11 in the etiopathology of Alzheimer's disease Neurobiology of Aging. 25: S441. DOI: 10.1016/S0197-4580(04)81453-2  0.408
2004 Sager KL, Lah JJ, Levey AI, Rees HD, Mufson EJ, Bennett DA, Wuu J, Leurgans S. P3-295 Quantification of LR11 expression in mild cognitive impairment, a human model for early Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81445-3  0.413
2004 Jones KA, Carter S, Shoemaker JT, Solomon IG, Lah J, Levey A, Decker MJ. P1-247 Intermitten hypoxic insults occurring during a period of critical brain development reduce the expression of insoluble beta amyloid within the hippocampus Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80560-8  0.318
2004 Zola S, Levey A, Lah J, Ouslander J. P1-075 Behavioral tasks and eye-tracking technology for early diagnosis of Alzheimer's disease in patients with mild cognitive impairment (MCI) Neurobiology of Aging. 25: S116. DOI: 10.1016/S0197-4580(04)80389-0  0.367
2004 Goldstein FC, Ashley AV, Freedman LJ, Cellar J, Harrison J, Lah JJ, Levey AI. P1-023 Functional abilities in patients with mild cognitive impairment versus Alzheimer's disease and normal controls Neurobiology of Aging. 25: S100. DOI: 10.1016/S0197-4580(04)80337-3  0.405
2003 Hill K, Li Y, Bennett M, McKay M, Zhu X, Shern J, Torre E, Lah JJ, Levey AI, Kahn RA. Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein. The Journal of Biological Chemistry. 278: 36032-40. PMID 12842896 DOI: 10.1074/Jbc.M301632200  0.302
2003 Huse JT, Byant D, Yang Y, Pijak DS, D'Souza I, Lah JJ, Lee VM, Doms RW, Cook DG. Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation. The Journal of Biological Chemistry. 278: 17141-9. PMID 12551920 DOI: 10.1074/Jbc.M213303200  0.309
2000 Lah JJ, Levey AI. Endogenous presenilin-1 targets to endocytic rather than biosynthetic compartments. Molecular and Cellular Neurosciences. 16: 111-26. PMID 10924255 DOI: 10.1006/Mcne.2000.0861  0.35
1997 Levey AI, Heilman CJ, Lah JJ, Nash NR, Rees HD, Wakai M, Mirra SS, Rye DB, Nochlin D, Bird TD, Mufson EJ. Presenilin-1 protein expression in familial and sporadic Alzheimer's disease. Annals of Neurology. 41: 742-53. PMID 9189035 DOI: 10.1002/Ana.410410610  0.43
1997 Lah JJ, Heilman CJ, Nash NR, Rees HD, Yi H, Counts SE, Levey AI. Light and electron microscopic localization of presenilin-1 in primate brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1971-80. PMID 9045726 DOI: 10.1523/Jneurosci.17-06-01971.1997  0.335
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