Morgan H. James - Publications

Affiliations: 
Anatomy The University of Newcastle 
Area:
Addiction Neurobiology , VTA, Hypothalamus

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Millard SJ, Hoang IB, Sherwood S, Taira M, Reyes V, Greer Z, O'Connor SL, Wassum KM, James MH, Barker DJ, Sharpe MJ. Cognitive representations of intracranial self-stimulation of midbrain dopamine neurons depend on stimulation frequency. Nature Neuroscience. PMID 38741021 DOI: 10.1038/s41593-024-01643-1  0.754
2023 Zhang VY, O'Connor SL, Welsh WJ, James MH. Machine learning models to predict ligand binding affinity for the orexin 1 receptor. Artificial Intelligence Chemistry. 2. PMID 38476266 DOI: 10.1016/j.aichem.2023.100040  0.733
2023 Knowles LG, Armanious AJ, Peng Y, Welsh WJ, James MH. Recent advances in drug discovery efforts targeting the sigma 1 receptor system: Implications for novel medications designed to reduce excessive drug and food seeking. Addiction Neuroscience. 8. PMID 37753198 DOI: 10.1016/j.addicn.2023.100126  0.303
2022 James MH, Aston-Jones G. Orexin Reserve: A Mechanistic Framework for the Role of Orexins (Hypocretins) in Addiction. Biological Psychiatry. 92: 836-844. PMID 36328706 DOI: 10.1016/j.biopsych.2022.06.027  0.326
2022 Giannotti G, Mottarlini F, Heinsbroek JA, Mandel MR, James MH, Peters J. Oxytocin and orexin systems bidirectionally regulate the ability of opioid cues to bias reward seeking. Translational Psychiatry. 12: 432. PMID 36195606 DOI: 10.1038/s41398-022-02161-z  0.311
2022 O'Connor SL, Aston-Jones G, James MH. Novelty preference does not predict trait cocaine behaviors in male rats. Addiction Neuroscience. 2. PMID 35425947 DOI: 10.1016/j.addicn.2022.100013  0.811
2021 Brown RM, Dayas C, James M, Smith RJ. NEW DIRECTIONS IN MODELLING DYSREGULATED REWARD SEEKING FOR FOOD AND DRUGS. Neuroscience and Biobehavioral Reviews. PMID 34736883 DOI: 10.1016/j.neubiorev.2021.10.043  0.712
2021 Mehr JB, Bilotti MM, James MH. Orexin (hypocretin) and addiction. Trends in Neurosciences. 44: 852-855. PMID 34642086 DOI: 10.1016/j.tins.2021.09.002  0.332
2021 Pantazis CB, James MH, O'Connor S, Shin N, Aston-Jones G. Orexin-1 receptor signaling in ventral tegmental area mediates cue-driven demand for cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34635803 DOI: 10.1038/s41386-021-01173-5  0.808
2021 O'Connor SL, Aston-Jones G, James MH. The sensation-seeking trait confers a dormant susceptibility to addiction that is revealed by intermittent cocaine self-administration in rats. Neuropharmacology. 108566. PMID 33862028 DOI: 10.1016/j.neuropharm.2021.108566  0.808
2020 James MH, Fragale JE, O'Connor SL, Zimmer BA, Aston-Jones G. The orexin (hypocretin) neuropeptide system is a target for novel therapeutics to treat cocaine use disorder with alcohol co-abuse. Neuropharmacology. 108359. PMID 33091458 DOI: 10.1016/j.neuropharm.2020.108359  0.804
2020 Fragale JE, James MH, Aston-Jones G. Intermittent self-administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system. Addiction Biology. e12946. PMID 32798290 DOI: 10.1111/Adb.12946  0.526
2020 James MH. Mimicking Human Drug Consumption Patterns in Rat Engages Corticostriatal Circuitry. Neuroscience. PMID 32682655 DOI: 10.1016/J.Neuroscience.2020.06.012  0.338
2020 James MH, Mahler SV. Do striatal push/pull circuits hold the key to compulsive, relapsing heroin addiction? : A Research Highlight on: Chemogenetic modulation of accumbens direct or indirect pathways bidirectionally alters reinstatement of heroin-seeking in high- but not low-risk rats, by O'Neal et al. (2019). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31974443 DOI: 10.1038/S41386-020-0615-1  0.346
2019 Mohammadkhani A, Fragale JE, Pantazis CB, Bowrey HE, James MH, Aston-Jones G. Orexin-1 receptor signaling in ventral pallidum regulates motivation for the opioid remifentanil. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31641055 DOI: 10.1523/Jneurosci.0255-19.2019  0.435
2019 Bello NT, Yeh CY, James MH. Reduced Sensory-Evoked Locus Coeruleus-Norepinephrine Neural Activity in Female Rats With a History of Dietary-Induced Binge Eating. Frontiers in Psychology. 10: 1966. PMID 31551861 DOI: 10.3389/Fpsyg.2019.01966  0.354
2019 Mohammadkhani A, James MH, Pantazis CB, Aston-Jones G. Persistent effects of the orexin-1 receptor antagonist SB-334867 on motivation for the fast acting opioid remifentanil. Brain Research. 146461. PMID 31526801 DOI: 10.1016/J.Brainres.2019.146461  0.438
2019 Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. Addiction Biology. e12795. PMID 31297913 DOI: 10.1111/Adb.12795  0.564
2019 Fragale JE, Pantazis CB, James MH, Aston-Jones G. The role of orexin-1 receptor signaling in demand for the opioid fentanyl. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31112988 DOI: 10.1038/S41386-019-0420-X  0.424
2019 Wiskerke J, James MH, Aston-Jones G. The orexin-1 receptor antagonist SB-334867 reduces motivation, but not inhibitory control, in a rat stop signal task. Brain Research. PMID 31002819 DOI: 10.1016/J.Brainres.2019.04.017  0.426
2018 Yeoh JW, James MH, Adams CD, Bains JS, Sakurai T, Aston-Jones G, Graham BA, Dayas CV. Activation of lateral hypothalamic group III mGluRs suppresses cocaine-seeking following abstinence and normalizes drug-associated increases in excitatory drive to orexin/hypocretin cells. Neuropharmacology. PMID 30253175 DOI: 10.1016/J.Neuropharm.2018.09.033  0.792
2018 James MH, Bowrey HE, Stopper CM, Aston-Jones G. Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin-1 receptor antagonist in rats. The European Journal of Neuroscience. PMID 30240516 DOI: 10.1111/Ejn.14166  0.52
2018 James MH, Stopper CM, Zimmer BA, Koll NE, Bowrey HE, Aston-Jones G. Increased Number and Activity of a Lateral Subpopulation of Hypothalamic Orexin/Hypocretin Neurons Underlies the Expression of an Addicted State in Rats. Biological Psychiatry. PMID 30219208 DOI: 10.1016/J.Biopsych.2018.07.022  0.415
2017 James MH, McGlinchey EM, Vattikonda A, Mahler SV, Aston-Jones G. Cued reinstatement of cocaine- but not sucrose-seeking is dependent upon dopamine signaling in prelimbic cortex and is associated with recruitment of prelimbic neurons that project to contralateral nucleus accumbens core. The International Journal of Neuropsychopharmacology. PMID 29165565 DOI: 10.1093/Ijnp/Pyx107  0.494
2017 Quinn RK, James MH, Hawkins GE, Brown AL, Heathcote A, Smith DW, Cairns MJ, Dayas CV. Temporally specific miRNA expression patterns in the dorsal and ventral striatum of addiction-prone rats. Addiction Biology. PMID 28612502 DOI: 10.1111/Adb.12520  0.708
2017 James MH, Aston-Jones G. Orexin/Hypocretin, Central Amygdala, and Escalation of Cocaine Intake. Biological Psychiatry. 81: 552-553. PMID 28283054 DOI: 10.1016/J.Biopsych.2017.01.010  0.528
2017 James MH, Campbell EJ, Dayas CV. Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders. Current Topics in Behavioral Neurosciences. PMID 28083790 DOI: 10.1007/7854_2016_56  0.668
2016 James MH, Mahler SV, Moorman DE, Aston-Jones G. A Decade of Orexin/Hypocretin and Addiction: Where Are We Now? Current Topics in Behavioral Neurosciences. PMID 28012090 DOI: 10.1007/7854_2016_57  0.493
2016 Moorman DE, James MH, Kilroy EA, Aston-Jones G. Orexin/hypocretin-1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats. Brain Research. PMID 27771284 DOI: 10.1016/J.Brainres.2016.10.018  0.368
2016 James MH, Aston-Jones G. The Ventral Pallidum: Proposed Integrator of Positive and Negative Factors in Cocaine Abuse. Neuron. 92: 5-8. PMID 27710789 DOI: 10.1016/J.Neuron.2016.09.042  0.525
2016 McGlinchey EM, James MH, Mahler SV, Pantazis C, Aston-Jones G. Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8700-11. PMID 27535915 DOI: 10.1523/Jneurosci.1291-15.2016  0.592
2016 James MH, Quinn R, Ong LK, Levi EM, Smith DW, Dickson PW, Dayas CV. Rapamycin reduces motivated responding for cocaine and alters GluA1 expression inthe ventral but not dorsal striatum. European Journal of Pharmacology. PMID 27181066 DOI: 10.1016/J.Ejphar.2016.05.013  0.772
2016 Moorman DE, James MH, Kilroy EA, Aston-Jones G. Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner. The European Journal of Neuroscience. PMID 26750264 DOI: 10.1111/Ejn.13170  0.388
2014 Moorman DE, James MH, McGlinchey EM, Aston-Jones G. Differential roles of medial prefrontal subregions in the regulation of drug seeking. Brain Research. PMID 25529632 DOI: 10.1016/J.Brainres.2014.12.024  0.504
2014 Yeoh JW, James MH, Graham BA, Dayas CV. Electrophysiological characteristics of paraventricular thalamic (PVT) neurons in response to cocaine and cocaine- and amphetamine-regulated transcript (CART). Frontiers in Behavioral Neuroscience. 8: 280. PMID 25309361 DOI: 10.3389/Fnbeh.2014.00280  0.814
2014 Mahler SV, Moorman DE, Smith RJ, James MH, Aston-Jones G. Motivational activation: a unifying hypothesis of orexin/hypocretin function. Nature Neuroscience. 17: 1298-303. PMID 25254979 DOI: 10.1038/Nn.3810  0.366
2014 James MH, Campbell EJ, Walker FR, Smith DW, Richardson HN, Hodgson DM, Dayas CV. Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats. Frontiers in Behavioral Neuroscience. 8: 244. PMID 25100956 DOI: 10.3389/Fnbeh.2014.00244  0.656
2014 Zouikr I, James MH, Campbell EJ, Clifton VL, Beagley KW, Dayas CV, Hodgson DM. Altered formalin-induced pain and Fos induction in the periaqueductal grey of preadolescent rats following neonatal LPS exposure. Plos One. 9: e98382. PMID 24878577 DOI: 10.1371/Journal.Pone.0098382  0.641
2014 Yeoh JW, Campbell EJ, James MH, Graham BA, Dayas CV. Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls. Frontiers in Neuroscience. 8: 36. PMID 24616658 DOI: 10.3389/Fnins.2014.00036  0.726
2014 James MH, Quinn RK, Ong LK, Levi EM, Charnley JL, Smith DW, Dickson PW, Dayas CV. mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1694-702. PMID 24469593 DOI: 10.1038/Npp.2014.16  0.804
2014 Hodgson D, Campbell E, Zouikr I, Watters S, James M, Dayas C. 94. The involvement of orexin (hypocretin) in the formalin-induced inflammatory pain response in adulthood following a neonatal bacterial immune challenge Brain, Behavior, and Immunity. 40: e27-e28. DOI: 10.1016/J.Bbi.2014.06.114  0.642
2013 James MH, Dayas CV. What about me…? The PVT: a role for the paraventricular thalamus (PVT) in drug-seeking behavior. Frontiers in Behavioral Neuroscience. 7: 18. PMID 23509439 DOI: 10.3389/Fnbeh.2013.00018  0.71
2013 James MH, Yeoh JW, Graham BA, Dayas CV. Insights for Developing Pharmacological Treatments for Psychostimulant Relapse Targeting Hypothalamic Peptide Systems Journal of Addiction Research and Therapy. 2013: 2-13. DOI: 10.4172/2155-6105.S4-008  0.484
2012 Yeoh JW, James MH, Jobling P, Bains JS, Graham BA, Dayas CV. Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus. The Journal of Physiology. 590: 3677-89. PMID 22641785 DOI: 10.1113/Jphysiol.2012.230268  0.8
2011 James MH, Charnley JL, Flynn JR, Smith DW, Dayas CV. Propensity to 'relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei. Neuroscience. 199: 235-42. PMID 21985936 DOI: 10.1016/J.Neuroscience.2011.09.047  0.777
2011 James MH, Charnley JL, Levi EM, Jones E, Yeoh JW, Smith DW, Dayas CV. Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 684-90. PMID 21447232 DOI: 10.1017/S1461145711000423  0.808
2010 James MH, Charnley JL, Jones E, Levi EM, Yeoh JW, Flynn JR, Smith DW, Dayas CV. Cocaine- and amphetamine-regulated transcript (CART) signaling within the paraventricular thalamus modulates cocaine-seeking behaviour. Plos One. 5: e12980. PMID 20886038 DOI: 10.1371/Journal.Pone.0012980  0.821
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