Andrea G. Nackley - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pain Neurobiology and Genetics

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wu PY, Caceres AI, Chen J, Sokoloff J, Huang M, Baht GS, Nackley AG, Jordt SE, Terrando N. Vagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice. Pain. PMID 38422485 DOI: 10.1097/j.pain.0000000000003181  0.39
2023 Wu PY, Caceres AI, Chen J, Sokoloff J, Huang M, Baht GS, Nackley AG, Jordt SE, Terrando N. Vagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice. Biorxiv : the Preprint Server For Biology. PMID 37292744 DOI: 10.1101/2023.05.16.540949  0.418
2023 Scarneo S, Zhang X, Wang Y, Camacho-Domenech J, Ricano J, Hughes P, Haystead T, Nackley AG. Transforming growth factor-β-activated kinase 1 (TAK1) mediates chronic pain and cytokine production in mouse models of inflammatory, neuropathic, and primary pain. The Journal of Pain. PMID 37121498 DOI: 10.1016/j.jpain.2023.04.011  0.515
2022 Suttle A, Wang P, Dias FC, Zhang Q, Luo Y, Simmons L, Bortsov A, Tchivileva IE, Nackley AG, Chen Y. Sensory Neuron-TRPV4 Modulates Temporomandibular Disorder Pain Via CGRP in Mice. The Journal of Pain. PMID 36509176 DOI: 10.1016/j.jpain.2022.12.001  0.429
2022 Carey ET, Geller EJ, Rapkin A, Farb D, Cutting H, Akaninwor J, Stirling C, Bortsov A, McNulty S, Merrill P, Zakroysky P, DeLaRosa J, Luo S, Nackley AG. Rationale and design of a multicenter randomized clinical trial of vestibulodynia: understanding pathophysiology and determining appropriate treatments (vestibulodynia: UPDATe). Annals of Medicine. 54: 2885-2897. PMID 36269028 DOI: 10.1080/07853890.2022.2132531  0.44
2022 Parisien M, Lima LV, Dagostino C, El-Hachem N, Drury GL, Grant AV, Huising J, Verma V, Meloto CB, Silva JR, Dutra GGS, Markova T, Dang H, Tessier PA, Slade GD, ... Nackley AG, et al. Acute inflammatory response via neutrophil activation protects against the development of chronic pain. Science Translational Medicine. 14: eabj9954. PMID 35544595 DOI: 10.1126/scitranslmed.abj9954  0.698
2021 Wang Y, Scarneo SA, Kim SH, Zhang X, Chen J, Yang KW, Hughes P, Haystead T, Nackley AG. Expression of ectopic heat shock protein 90 in male and female primary afferent nociceptors regulates inflammatory pain. Pain. PMID 34995041 DOI: 10.1097/j.pain.0000000000002511  0.413
2021 Ji J, He Q, Luo X, Bang S, Matsuoka Y, McGinnis A, Nackley AG, Ji RR. IL-23 Enhances C-Fiber-Mediated and Blue Light-Induced Spontaneous Pain in Female Mice. Frontiers in Immunology. 12: 787565. PMID 34950149 DOI: 10.3389/fimmu.2021.787565  0.353
2021 Luo X, Chen O, Wang Z, Bang S, Ji J, Lee SH, Huh Y, Furutani K, He Q, Tao X, Ko MC, Bortsov A, Donnelly CR, Chen Y, Nackley A, et al. IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice. Neuron. 109: 2691-2706.e5. PMID 34473953 DOI: 10.1016/j.neuron.2021.06.015  0.385
2020 Gaynor SM, Bortsov A, Bair E, Fillingim RB, Greenspan JD, Ohrbach R, Diatchenko L, Nackley A, Tchivileva IE, Whitehead W, Alonso AA, Buchheit TE, Boortz-Marx RL, Liedtke W, Park JJ, et al. Phenotypic profile clustering pragmatically identifies diagnostically and mechanistically informative subgroups of chronic pain patients. Pain. PMID 33259458 DOI: 10.1097/j.pain.0000000000002153  0.805
2020 Khoury S, Wang QP, Parisien M, Gris P, Bortsov AV, Linnstaedt SD, McLean SA, Tungate AS, Sofer T, Lee J, Louie T, Redline S, Kaunisto MA, Kalso EA, Munter HM, ... Nackley AG, et al. Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons. Sleep. PMID 33034629 DOI: 10.1093/sleep/zsaa211  0.719
2020 van Tilburg MA, Parisien M, Boles RG, Drury GL, Smith-Voudouris J, Verma V, Khoury S, Chabot-Doré AJ, Nackley AG, Smith SB, Whitehead WE, Zolnoun DA, Slade GD, Tchivileva I, Maixner W, et al. A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia. Pain. PMID 32658146 DOI: 10.1097/J.Pain.0000000000001996  0.803
2020 Zhang X, Kanter K, Chen J, Kim S, Wang Y, Adeyemi C, OʼBuckley SC, Nackley AG. Low catechol-O-methyltransferase and stress potentiate functional pain and depressive behavior, especially in female mice. Pain. 161: 446-458. PMID 31972854 DOI: 10.1097/j.pain.0000000000001734  0.416
2019 Zhang X, Kanter K, Chen J, Kim S, Wang Y, Adeyemi C, O'Buckley SC, Nackley AG. Low COMT and Stress Potentiate Functional Pain and Depressive Behavior, Especially in Female Mice. Pain. PMID 31815911 DOI: 10.1097/j.pain.0000000000001734  0.301
2018 Smith SB, Parisien M, Bair E, Belfer I, Chabot-Doré AJ, Gris P, Khoury S, Tansley S, Torosyan Y, Zaykin DV, Bernhardt O, de Oliveira Serrano P, Gracely RH, Jain D, Järvelin MR, ... ... Nackley AG, et al. Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males. Pain. PMID 30431558 DOI: 10.1097/J.Pain.0000000000001438  0.839
2018 Shepherd SD, O'Buckley SC, Harrington JM, Haines LG, Rothrock GD, Johnson LM, Nackley AG. A moldable sustained release bupivacaine formulation for tailored treatment of postoperative dental pain. Scientific Reports. 8: 12172. PMID 30111777 DOI: 10.1038/s41598-018-29696-w  0.389
2018 Kim S, Zhang X, O'Buckley SC, Cooter M, Park JJ, Nackley AG. Acupuncture Resolves Persistent Pain and Neuroinflammation in a Mouse Model of Chronic Overlapping Pain Conditions. The Journal of Pain : Official Journal of the American Pain Society. PMID 29981376 DOI: 10.1016/j.jpain.2018.05.013  0.549
2018 Zhang X, Hartung JE, Bortsov AV, Kim S, O'Buckley SC, Kozlowski J, Nackley AG. Sustained Stimulation of β- and β-adrenergic Receptors Leads to Persistent Functional Pain and Neuroinflammation. Brain, Behavior, and Immunity. PMID 29935309 DOI: 10.1016/J.Bbi.2018.06.017  0.819
2018 Ji RR, Nackley A, Huh Y, Terrando N, Maixner W. Neuroinflammation and Central Sensitization in Chronic and Widespread Pain. Anesthesiology. PMID 29462012 DOI: 10.1097/Aln.0000000000002130  0.703
2017 Martin LJ, Smith SB, Khoutorsky A, Magnussen CA, Samoshkin A, Sorge RE, Cho C, Yosefpour N, Sivaselvachandran S, Tohyama S, Cole T, Khuong TM, Mir E, Gibson DG, Wieskopf JS, ... ... Nackley AG, et al. Epiregulin and EGFR interactions are involved in pain processing. The Journal of Clinical Investigation. PMID 28783046 DOI: 10.1172/Jci87406  0.821
2016 Geller EJ, Babb E, Nackley AG, Zolnoun D. Incidence and risk factors for pelvic pain following mesh implant surgery for the treatment of pelvic floor disorders. Journal of Minimally Invasive Gynecology. PMID 27773810 DOI: 10.1016/j.jmig.2016.10.001  0.439
2016 Harmon JB, Sanders AE, Wilder RS, Essick GK, Slade GD, Hartung JE, Nackley AG. Circulating Omentin-1 and Chronic Painful Temporomandibular Disorders. Journal of Oral & Facial Pain and Headache. 30: 203-209. PMID 27472522 DOI: 10.11607/Ofph.1608  0.828
2016 Oladosu FA, Ciszek BP, O'Buckley SC, Nackley AG. Novel intrathecal and subcutaneous catheter delivery systems in the mouse. Journal of Neuroscience Methods. PMID 26976722 DOI: 10.1016/J.Jneumeth.2016.03.006  0.74
2016 Ciszek BP, O'Buckley SC, Nackley AG. Persistent Catechol-O-methyltransferase-dependent Pain Is Initiated by Peripheral β-Adrenergic Receptors. Anesthesiology. PMID 26950706 DOI: 10.1097/ALN.0000000000001070  0.741
2016 Hartung J, Ciszek B, O'Buckley S, Nackley A. (374) Distinct mechanisms underlie the development and maintenance of COMT-dependent pain The Journal of Pain. 17: S68. DOI: 10.1016/J.Jpain.2016.01.281  0.836
2016 Ciszek B, O'Buckley S, Nackley A. (312) Peripherally located β2- and β3-adrenergic receptors contribute to the development of COMT-dependent pain in rats, but not the maintenance of pain in COMT-/- mice The Journal of Pain. 17: S53-S54. DOI: 10.1016/J.Jpain.2016.01.219  0.731
2015 Oladosu FA, Conrad MS, O'Buckley SC, Rashid NU, Slade GD, Nackley AG. Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia. Plos One. 10: e0135711. PMID 26270813 DOI: 10.1371/Journal.Pone.0135711  0.787
2015 Oladosu FA, Maixner W, Nackley AG. Alternative Splicing of G Protein-Coupled Receptors: Relevance to Pain Management. Mayo Clinic Proceedings. 90: 1135-51. PMID 26250730 DOI: 10.1016/j.mayocp.2015.06.010  0.814
2015 Oladosu FA, Maixner W, Nackley AG. Alternative Splicing of G Protein-Coupled Receptors: Relevance to Pain Management. Mayo Clinic Proceedings. 90: 1135-51. PMID 26250730 DOI: 10.1016/j.mayocp.2015.06.010  0.386
2015 Hartung JE, Eskew O, Wong T, Tchivileva IE, Oladosu FA, O'Buckley SC, Nackley AG. Nuclear factor-kappa B regulates pain and COMT expression in a rodent model of inflammation. Brain, Behavior, and Immunity. PMID 26187567 DOI: 10.1016/J.Bbi.2015.07.014  0.81
2015 Ciszek BP, Khan AA, Dang H, Slade GD, Smith S, Bair E, Maixner W, Zolnoun D, Nackley AG. MicroRNA expression profiles differentiate chronic pain condition subtypes. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 26166255 DOI: 10.1016/J.Trsl.2015.06.008  0.812
2015 Applebaum E, Nackley AG, Bair E, Maixner W, Khan AA. Genetic Variants in Cyclooxygenase-2 Contribute to Post-treatment Pain among Endodontic Patients. Journal of Endodontics. PMID 26081267 DOI: 10.1016/j.joen.2015.04.021  0.697
2015 Kline RH, Exposto FG, O'Buckley SC, Westlund KN, Nackley AG. Catechol-O-methyltransferase inhibition alters pain and anxiety-related volitional behaviors through activation of β-adrenergic receptors in the rat. Neuroscience. 290: 561-9. PMID 25659347 DOI: 10.1016/j.neuroscience.2015.01.064  0.574
2015 Babb E, Zolnoun D, Nackley A, Khan A, Geller E. Prevalence and Risk Factors for Pelvic Pain following Mesh Implant Surgery for the Treatment of Pelvic Organ Prolapse and Stress Urinary Incontinence Journal of Minimally Invasive Gynecology. 22: S49. DOI: 10.1016/J.JMIG.2014.12.101  0.387
2014 Smith SB, Reenilä I, Männistö PT, Slade GD, Maixner W, Diatchenko L, Nackley AG. Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain. Pain. 155: 2390-9. PMID 25218601 DOI: 10.1016/J.Pain.2014.09.009  0.801
2014 Hartung JE, Ciszek BP, Nackley AG. β2- and β3-adrenergic receptors drive COMT-dependent pain by increasing production of nitric oxide and cytokines. Pain. 155: 1346-55. PMID 24727346 DOI: 10.1016/J.Pain.2014.04.011  0.818
2014 Nackley AG. Molecular correlates of localized versus co-occurring chronic pain conditions Molecular Pain. 10: O11. DOI: 10.1186/1744-8069-10-S1-O11  0.582
2014 Hartung J, Nackley A. 127. B2-and B3-adrenergic receptors drive the development of COMT-dependent pain by increasing release of NO and innate immune cytokines Brain, Behavior, and Immunity. 40: e37. DOI: 10.1016/J.Bbi.2014.06.147  0.828
2013 Chen H, Nackley A, Miller V, Diatchenko L, Maixner W. Multisystem dysregulation in painful temporomandibular disorders. The Journal of Pain : Official Journal of the American Pain Society. 14: 983-96. PMID 23721875 DOI: 10.1016/j.jpain.2013.03.011  0.783
2012 Sanders AE, Maixner W, Nackley AG, Diatchenko L, By K, Miller VE, Slade GD. Excess risk of temporomandibular disorder associated with cigarette smoking in young adults. The Journal of Pain : Official Journal of the American Pain Society. 13: 21-31. PMID 22036516 DOI: 10.1016/J.Jpain.2011.08.003  0.631
2011 Slade GD, Conrad MS, Diatchenko L, Rashid NU, Zhong S, Smith S, Rhodes J, Medvedev A, Makarov S, Maixner W, Nackley AG. Cytokine biomarkers and chronic pain: association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness. Pain. 152: 2802-12. PMID 22000099 DOI: 10.1016/J.Pain.2011.09.005  0.775
2010 Segall SK, Nackley AG, Diatchenko L, Lariviere WR, Lu X, Marron JS, Grabowski-Boase L, Walker JR, Slade G, Gauthier J, Bailey JS, Steffy BM, Maynard TM, Tarantino LM, Wiltshire T. Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice. Genes, Brain, and Behavior. 9: 933-46. PMID 20659173 DOI: 10.1111/J.1601-183X.2010.00633.X  0.81
2010 Gris P, Gauthier J, Cheng P, Gibson DG, Gris D, Laur O, Pierson J, Wentworth S, Nackley AG, Maixner W, Diatchenko L. A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism. Molecular Pain. 6: 33. PMID 20525224 DOI: 10.1186/1744-8069-6-33  0.66
2010 Cevidanes LH, Hajati AK, Paniagua B, Lim PF, Walker DG, Palconet G, Nackley AG, Styner M, Ludlow JB, Zhu H, Phillips C. Quantification of condylar resorption in temporomandibular joint osteoarthritis. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 110: 110-7. PMID 20382043 DOI: 10.1016/J.Tripleo.2010.01.008  0.452
2010 Nackley AG, Diatchenko L. Assessing potential functionality of catechol-O-methyltransferase (COMT) polymorphisms associated with pain sensitivity and temporomandibular joint disorders. Methods in Molecular Biology (Clifton, N.J.). 617: 375-93. PMID 20336436 DOI: 10.1007/978-1-60327-323-7_28  0.683
2010 Nackley A, Conrad M, Slade G, Smith S, Gibson D, Kasravi P, Miller V, Lim P, Maixner W, Diatchenko L. Cytokines associated with TMD case status and related intermediate phenotypes The Journal of Pain. 11: S18. DOI: 10.1016/J.Jpain.2010.01.077  0.687
2009 Tchivileva IE, Tan KS, Gambarian M, Nackley AG, Medvedev AV, Romanov S, Flood PM, Maixner W, Makarov SS, Diatchenko L. Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytes. Molecular Immunology. 46: 2256-66. PMID 19477016 DOI: 10.1016/J.Molimm.2009.04.008  0.636
2009 Nackley AG, Shabalina SA, Lambert JE, Conrad MS, Gibson DG, Spiridonov AN, Satterfield SK, Diatchenko L. Low enzymatic activity haplotypes of the human catechol-O-methyltransferase gene: enrichment for marker SNPs. Plos One. 4: e5237. PMID 19365560 DOI: 10.1371/journal.pone.0005237  0.631
2009 Tchivileva IE, Nackley AG, Qian L, Wentworth S, Conrad M, Diatchenko LB. Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase. Molecular Pain. 5: 13. PMID 19291302 DOI: 10.1186/1744-8069-5-13  0.694
2008 Conrad M, Arunasalam R, Gibson D, Bair E, Smith S, Slade G, Maixner W, Diatchenko L, Nackley A. (169) Proinflammatory cytokine profiles associated with TMD case status and related intermediate phenotypes The Journal of Pain. 9: 18. DOI: 10.1016/J.Jpain.2008.01.089  0.688
2007 Diatchenko L, Nackley AG, Tchivileva IE, Shabalina SA, Maixner W. Genetic architecture of human pain perception. Trends in Genetics : Tig. 23: 605-13. PMID 18023497 DOI: 10.1016/j.tig.2007.09.004  0.77
2007 Diatchenko L, Slade GD, Nackley AG, Maixner W. Responses to Drs. Kim and Dionne regarding comments on Diatchenko, et al. Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. Pain 2006; 125: 216-24. Pain. 129: 366-370. PMID 17851590 DOI: 10.1016/J.Pain.2007.02.012  0.749
2007 Nackley AG, Tan KS, Fecho K, Flood P, Diatchenko L, Maixner W. Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors. Pain. 128: 199-208. PMID 17084978 DOI: 10.1016/J.Pain.2006.09.022  0.766
2007 Tan KS, Nackley AG, Satterfield K, Maixner W, Diatchenko L, Flood PM. Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms. Cellular Signalling. 19: 251-60. PMID 16996249 DOI: 10.1016/J.Cellsig.2006.06.007  0.637
2007 Nackley A, Tchivileva I, Conrad M, Cooke B, Maixner W, Diatchenko L. (649) The Journal of Pain. 8: S13. DOI: 10.1016/j.jpain.2007.02.060  0.626
2007 Tchivileva I, Nackley A, Maixner W, Diatchenko L. (610) The Journal of Pain. 8: S3. DOI: 10.1016/j.jpain.2007.02.012  0.626
2006 Nackley AG, Shabalina SA, Tchivileva IE, Satterfield K, Korchynskyi O, Makarov SS, Maixner W, Diatchenko L. Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. Science (New York, N.Y.). 314: 1930-3. PMID 17185601 DOI: 10.1126/science.1131262  0.71
2006 Diatchenko L, Nackley AG, Slade GD, Bhalang K, Belfer I, Max MB, Goldman D, Maixner W. Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. Pain. 125: 216-24. PMID 16837133 DOI: 10.1016/J.Pain.2006.05.024  0.84
2006 Diatchenko L, Nackley AG, Slade GD, Fillingim RB, Maixner W. Idiopathic pain disorders--pathways of vulnerability. Pain. 123: 226-30. PMID 16777329 DOI: 10.1016/J.Pain.2006.04.015  0.783
2006 Nackley A, Diatchenko L, Maixner W. Perspectives on the genetic basis of opioid-induced hyperalgesia. Anesthesiology. 104: 909-10. PMID 16645440 DOI: 10.1097/00000542-200605000-00004  0.627
2005 Hohmann AG, Neely MH, Piña J, Nackley AG. Neonatal chronic hind paw inflammation alters sensitization to intradermal capsaicin in adult rats: a behavioral and immunocytochemical study. The Journal of Pain : Official Journal of the American Pain Society. 6: 798-808. PMID 16326368 DOI: 10.1016/j.jpain.2005.07.009  0.607
2005 Fecho K, Nackley AG, Wu Y, Maixner W. Basal and carrageenan-induced pain behavior in Sprague-Dawley, Lewis and Fischer rats. Physiology & Behavior. 85: 177-86. PMID 15924913 DOI: 10.1016/J.Physbeh.2005.03.018  0.718
2005 Diatchenko L, Slade GD, Nackley AG, Bhalang K, Sigurdsson A, Belfer I, Goldman D, Xu K, Shabalina SA, Shagin D, Max MB, Makarov SS, Maixner W. Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Human Molecular Genetics. 14: 135-43. PMID 15537663 DOI: 10.1093/Hmg/Ddi013  0.846
2005 Fecho K, Faison J, Manning E, Nackley A, Maixner W. Genetic differences in basal and inflammatory pain behavior and in morphine’s analgesic effects in the rat The Journal of Pain. 6: S14. DOI: 10.1016/j.jpain.2005.01.053  0.658
2004 Nackley AG, Zvonok AM, Makriyannis A, Hohmann AG. Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation. Journal of Neurophysiology. 92: 3562-74. PMID 15317842 DOI: 10.1152/Jn.00886.2003  0.603
2003 Gutierrez T, Nackley AG, Neely MH, Freeman KG, Edwards GL, Hohmann AG. Effects of neurotoxic destruction of descending noradrenergic pathways on cannabinoid antinociception in models of acute and tonic nociception. Brain Research. 987: 176-85. PMID 14499961 DOI: 10.1016/S0006-8993(03)03324-9  0.613
2003 Nackley AG, Makriyannis A, Hohmann AG. Selective activation of cannabinoid CB(2) receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation. Neuroscience. 119: 747-57. PMID 12809695 DOI: 10.1016/S0306-4522(03)00126-X  0.686
2003 Nackley AG, Suplita RL, Hohmann AG. A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation. Neuroscience. 117: 659-70. PMID 12617970 DOI: 10.1016/S0306-4522(02)00870-9  0.643
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