| Year |
Citation |
Score |
| 2023 |
Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM, Vasan N, Ma Y, Krismer K, Robles JT, van de Kooij B, ... ... Ryazanov AG, et al. An atlas of substrate specificities for the human serine/threonine kinome. Nature. PMID 36631611 DOI: 10.1038/s41586-022-05575-3 |
0.792 |
|
| 2020 |
Gosrani SP, Jester HM, Zhou X, Ryazanov AG, Ma T. Repression of eEF2 kinase improves deficits in novel object recognition memory in aged mice. Neurobiology of Aging. 95: 154-160. PMID 32810756 DOI: 10.1016/J.Neurobiolaging.2020.07.016 |
0.337 |
|
| 2019 |
Rios FJ, Zou ZG, Harvey AP, Harvey KY, Nosalski R, Anyfanti P, Camargo LL, Lacchini S, Ryazanov AG, Ryazanova L, McGrath S, Guzik TJ, Goodyear CS, Montezano AC, Touyz RM. Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis. Cardiovascular Research. PMID 31250885 DOI: 10.1093/Cvr/Cvz164 |
0.352 |
|
| 2019 |
Beckelman BC, Yang W, Kasica NP, Zimmermann HR, Zhou X, Keene CD, Ryazanov AG, Ma T. Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice. The Journal of Clinical Investigation. PMID 30667373 DOI: 10.1172/Jci122954 |
0.316 |
|
| 2018 |
Cheng Y, Ren X, Yuan Y, Shan Y, Li L, Chen X, Zhang L, Takahashi Y, Yang JW, Han B, Liao J, Li Y, Harvey H, Ryazanov A, Robertson GP, et al. Correction: eEF-2 kinase is a critical regulator of Warbrug effect through controlling PP2A-A synthesis. Oncogene. PMID 29973686 DOI: 10.1038/S41388-018-0322-0 |
0.335 |
|
| 2018 |
Zimmermann HR, Yang W, Beckelman BC, Kasica NP, Zhou X, Galli L, Ryazanov AG, Ma T. Genetic Removal of eIF2α Kinase PERK in Mice Enables Hippocampal L-LTP Independent of mTORC1 Activity. Journal of Neurochemistry. PMID 29337352 DOI: 10.1111/Jnc.14306 |
0.432 |
|
| 2016 |
De Gassart A, Demaria O, Panes R, Zaffalon L, Ryazanov AG, Gilliet M, Martinon F. Pharmacological eEF2K activation promotes cell death and inhibits cancer progression. Embo Reports. PMID 27572820 DOI: 10.15252/Embr.201642194 |
0.367 |
|
| 2016 |
Liao Y, Chu HP, Hu Z, Merkin JJ, Chen J, Liu Z, Degenhardt K, White E, Ryazanov AG. Paradoxical roles of elongation factor-2 kinase in stem cell survival. The Journal of Biological Chemistry. PMID 27466362 DOI: 10.1074/Jbc.M116.724856 |
0.41 |
|
| 2016 |
Nakano Y, Le MH, Abduweli D, Ho SP, Ryazanova LV, Hu Z, Ryazanov AG, Den Besten PK, Zhang Y. A Critical Role of TRPM7 As an Ion Channel Protein in Mediating the Mineralization of the Craniofacial Hard Tissues. Frontiers in Physiology. 7: 258. PMID 27458382 DOI: 10.3389/Fphys.2016.00258 |
0.392 |
|
| 2016 |
Heise C, Taha E, Murru L, Ponzoni L, Cattaneo A, Guarnieri FC, Montani C, Mossa A, Vezzoli E, Ippolito G, Zapata J, Barrera I, Ryazanov AG, Cook J, Poe M, et al. eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures. Cerebral Cortex (New York, N.Y. : 1991). PMID 27005990 DOI: 10.1093/Cercor/Bhw075 |
0.359 |
|
| 2016 |
Antunes TT, Callera GE, He Y, Yogi A, Ryazanov AG, Ryazanova LV, Zhai A, Stewart DJ, Shrier A, Touyz RM. Transient Receptor Potential Melastatin 7 Cation Channel Kinase: New Player in Angiotensin II-Induced Hypertension. Hypertension. PMID 26928801 DOI: 10.1161/Hypertensionaha.115.07021 |
0.397 |
|
| 2015 |
Zierler S, Sumoza-Toledo A, Suzuki S, Ó Dúill F, Ryazanova LV, Penner R, Ryazanov AG, Fleig A. TRPM7 kinase activity regulates murine mast cell degranulation. The Journal of Physiology. PMID 26660477 DOI: 10.1113/Jp271564 |
0.511 |
|
| 2015 |
von Hoven G, Neukirch C, Meyenburg M, Füser S, Petrivna MB, Rivas AJ, Ryazanov A, Kaufman RJ, Aroian RV, Husmann M. eIF2α Confers Cellular Tolerance to S. aureus α-Toxin. Frontiers in Immunology. 6: 383. PMID 26284068 DOI: 10.3389/Fimmu.2015.00383 |
0.487 |
|
| 2015 |
Faller WJ, Jackson TJ, Knight JR, Ridgway RA, Jamieson T, Karim SA, Jones C, Radulescu S, Huels DJ, Myant KB, Dudek KM, Casey HA, Scopelliti A, Cordero JB, Vidal M, ... ... Ryazanov AG, et al. mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature. 517: 497-500. PMID 25383520 DOI: 10.1038/Nature13896 |
0.37 |
|
| 2014 |
Ryazanova LV, Hu Z, Suzuki S, Chubanov V, Fleig A, Ryazanov AG. Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice. Scientific Reports. 4: 7599. PMID 25534891 DOI: 10.1038/Srep07599 |
0.507 |
|
| 2014 |
Nikonorova IA, Kornakov NV, Dmitriev SE, Vassilenko KS, Ryazanov AG. Identification of a Mg2+-sensitive ORF in the 5'-leader of TRPM7 magnesium channel mRNA. Nucleic Acids Research. 42: 12779-88. PMID 25326319 DOI: 10.1093/Nar/Gku951 |
0.42 |
|
| 2014 |
Chu HP, Liao Y, Novak JS, Hu Z, Merkin JJ, Shymkiv Y, Braeckman BP, Dorovkov MV, Nguyen A, Clifford PM, Nagele RG, Harrison DE, Ellis RE, Ryazanov AG. Germline quality control: eEF2K stands guard to eliminate defective oocytes. Developmental Cell. 28: 561-572. PMID 24582807 DOI: 10.1016/J.Devcel.2014.01.027 |
0.745 |
|
| 2014 |
Faller W, Jackson T, Ridgway R, Knight J, Jamieson T, Pende M, Ryazanov A, Sonenberg N, Meyuhas O, Bushell M, Hall M, Willis A, Sansom O. PWE-021 Mtorc1 Mediated Translational Elongation Is Limiting For Intestinal Tumour Initiation And Growth Gut. 63: A130.2-A131. DOI: 10.1136/Gutjnl-2014-307263.281 |
0.339 |
|
| 2013 |
Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, ... ... Ryazanov AG, et al. Construction of human activity-based phosphorylation networks. Molecular Systems Biology. 9: 655. PMID 23549483 DOI: 10.1038/Msb.2013.12 |
0.536 |
|
| 2013 |
Hizli AA, Chi Y, Swanger J, Carter JH, Liao Y, Welcker M, Ryazanov AG, Clurman BE. Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase. Molecular and Cellular Biology. 33: 596-604. PMID 23184662 DOI: 10.1128/Mcb.01270-12 |
0.541 |
|
| 2012 |
Abramczyk O, Tavares CDJ, Devkota AK, Ryazanov AG, Turk BE, Riggs AF, Ozpolat B, Dalby KN. Corrigendum to "Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli" [Protein Expression and Purification 79 (2011) 237-244] (DOI:10.1016/j.pep.2011.05.005) Protein Expression and Purification. DOI: 10.1016/J.Pep.2012.07.010 |
0.412 |
|
| 2011 |
Abramczyk O, Tavares CD, Devkota AK, Ryazanov AG, Turk BE, Riggs AF, Ozpolat B, Dalby KN. Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli. Protein Expression and Purification. 79: 237-44. PMID 21605678 DOI: 10.1016/J.Pep.2011.05.005 |
0.468 |
|
| 2011 |
Bewley MA, Pham TK, Marriott HM, Noirel J, Chu HP, Ow SY, Ryazanov AG, Read RC, Whyte MKB, Chain B, Wright PC, Dockrell DH. Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae Molecular and Cellular Proteomics. 10. PMID 21474794 DOI: 10.1074/Mcp.M111.008193 |
0.355 |
|
| 2011 |
Dorovkov MV, Kostyukova AS, Ryazanov AG. Phosphorylation of annexin A1 by TRPM7 kinase: a switch regulating the induction of an α-helix. Biochemistry. 50: 2187-93. PMID 21280599 DOI: 10.1021/Bi101963H |
0.771 |
|
| 2011 |
Perraud AL, Zhao X, Ryazanov AG, Schmitz C. The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k. Cellular Signalling. 23: 586-93. PMID 21112387 DOI: 10.1016/J.Cellsig.2010.11.011 |
0.602 |
|
| 2010 |
Ryazanova LV, Rondon LJ, Zierler S, Hu Z, Galli J, Yamaguchi TP, Mazur A, Fleig A, Ryazanov AG. TRPM7 is essential for Mg(2+) homeostasis in mammals. Nature Communications. 1: 109. PMID 21045827 DOI: 10.1038/Ncomms1108 |
0.509 |
|
| 2010 |
Khan AA, Dace DS, Ryazanov AG, Kelly J, Apte RS. Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway. The American Journal of Pathology. 177: 481-92. PMID 20472894 DOI: 10.2353/Ajpath.2010.090836 |
0.471 |
|
| 2008 |
Clark K, Middelbeek J, Dorovkov MV, Figdor CG, Ryazanov AG, Lasonder E, van Leeuwen FN. The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC. Febs Letters. 582: 2993-7. PMID 18675813 DOI: 10.1016/J.Febslet.2008.07.043 |
0.812 |
|
| 2008 |
Park S, Park JM, Kim S, Kim JA, Shepherd JD, Smith-Hicks CL, Chowdhury S, Kaufmann W, Kuhl D, Ryazanov AG, Huganir RL, Linden DJ, Worley PF. Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron. 59: 70-83. PMID 18614030 DOI: 10.1016/J.Neuron.2008.05.023 |
0.392 |
|
| 2008 |
Clark K, Middelbeek J, Lasonder E, Dulyaninova NG, Morrice NA, Ryazanov AG, Bresnick AR, Figdor CG, van Leeuwen FN. TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. Journal of Molecular Biology. 378: 790-803. PMID 18394644 DOI: 10.1016/J.Jmb.2008.02.057 |
0.485 |
|
| 2008 |
Boyce M, Py BF, Ryazanov AG, Minden JS, Long K, Ma D, Yuan J. A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death. Cell Death and Differentiation. 15: 589-99. PMID 18188169 DOI: 10.1038/Sj.Cdd.4402296 |
0.344 |
|
| 2006 |
Clark K, Langeslag M, van Leeuwen B, Ran L, Ryazanov AG, Figdor CG, Moolenaar WH, Jalink K, van Leeuwen FN. TRPM7, a novel regulator of actomyosin contractility and cell adhesion. The Embo Journal. 25: 290-301. PMID 16407977 DOI: 10.1038/Sj.Emboj.7600931 |
0.551 |
|
| 2005 |
Schmitz C, Dorovkov MV, Zhao X, Davenport BJ, Ryazanov AG, Perraud AL. The channel kinases TRPM6 and TRPM7 are functionally nonredundant. The Journal of Biological Chemistry. 280: 37763-71. PMID 16150690 DOI: 10.1074/Jbc.M509175200 |
0.768 |
|
| 2005 |
Hermosura MC, Nayakanti H, Dorovkov MV, Calderon FR, Ryazanov AG, Haymer DS, Garruto RM. A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders. Proceedings of the National Academy of Sciences of the United States of America. 102: 11510-5. PMID 16051700 DOI: 10.1073/Pnas.0505149102 |
0.75 |
|
| 2005 |
Heine M, Cramm-Behrens CI, Ansari A, Chu HP, Ryazanov AG, Naim HY, Jacob R. Alpha-kinase 1, a new component in apical protein transport. The Journal of Biological Chemistry. 280: 25637-43. PMID 15883161 DOI: 10.1074/Jbc.M502265200 |
0.45 |
|
| 2004 |
Dorovkov MV, Ryazanov AG. Phosphorylation of annexin I by TRPM7 channel-kinase. The Journal of Biological Chemistry. 279: 50643-6. PMID 15485879 DOI: 10.1074/Jbc.C400441200 |
0.82 |
|
| 2004 |
Drennan D, Ryazanov AG. Alpha-kinases: analysis of the family and comparison with conventional protein kinases. Progress in Biophysics and Molecular Biology. 85: 1-32. PMID 15050379 DOI: 10.1016/S0079-6107(03)00060-9 |
0.564 |
|
| 2004 |
Ryazanova LV, Dorovkov MV, Ansari A, Ryazanov AG. Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel. The Journal of Biological Chemistry. 279: 3708-16. PMID 14594813 DOI: 10.1074/Jbc.M308820200 |
0.818 |
|
| 2002 |
Dorovkov MV, Pavur KS, Petrov AN, Ryazanov AG. Regulation of elongation factor-2 kinase by pH. Biochemistry. 41: 13444-50. PMID 12416990 DOI: 10.1021/Bi026494P |
0.742 |
|
| 2002 |
Ryazanov AG. Elongation factor-2 kinase and its newly discovered relatives. Febs Letters. 514: 26-9. PMID 11904175 DOI: 10.1016/S0014-5793(02)02299-8 |
0.605 |
|
| 2002 |
Ryazanov AG, Nefsky BS. Protein turnover plays a key role in aging. Mechanisms of Ageing and Development. 123: 207-13. PMID 11718813 DOI: 10.1016/S0047-6374(01)00337-2 |
0.323 |
|
| 2001 |
Ryazanov AG. Molecular Biology. 35: 623-625. DOI: 10.1023/A:1010539430165 |
0.317 |
|
| 2001 |
Ryazanova LV, Pavur KS, Petrov AN, Dorovkov MV, Ryazanov AG. Molecular Biology. 35: 271-283. DOI: 10.1023/A:1010499720185 |
0.808 |
|
| 2000 |
Pavur KS, Petrov AN, Ryazanov AG. Mapping the functional domains of elongation factor-2 kinase. Biochemistry. 39: 12216-24. PMID 11015200 DOI: 10.1021/Bi0007270 |
0.565 |
|
| 2000 |
Tavernarakis N, Wang SL, Dorovkov M, Ryazanov A, Driscoll M. Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes. Nature Genetics. 24: 180-3. PMID 10655066 DOI: 10.1038/72850 |
0.713 |
|
| 1999 |
Enkemann SA, Pavur KS, Ryazanov AG, Berger SL. Does prothymosin α affect the phosphorylation of elongation factor 2? Journal of Biological Chemistry. 274: 18644-18650. PMID 10373476 DOI: 10.1074/Jbc.274.26.18644 |
0.444 |
|
| 1999 |
Ryazanov AG, Pavur KS, Dorovkov MV. Alpha-kinases: a new class of protein kinases with a novel catalytic domain. Current Biology : Cb. 9: R43-5. PMID 10021370 DOI: 10.1016/S0960-9822(99)80006-2 |
0.798 |
|
| 1998 |
Laitusis AL, Brostrom CO, Ryazanov AG, Brostrom MA. An examination of the role of increased cytosolic free Ca2+ concentrations in the inhibition of mRNA translation. Archives of Biochemistry and Biophysics. 354: 270-80. PMID 9637736 DOI: 10.1006/Abbi.1998.0712 |
0.392 |
|
| 1997 |
Ryazanov AG, Ward MD, Mendola CE, Pavur KS, Dorovkov MV, Wiedmann M, Erdjument-Bromage H, Tempst P, Parmer TG, Prostko CR, Germino FJ, Hait WN. Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 4884-9. PMID 9144159 DOI: 10.1073/Pnas.94.10.4884 |
0.81 |
|
| 1997 |
Hait WN, Ward MD, Trakht IN, Ryazanov AG. Elongation factor-2 kinase: immunological evidence for the existence of tissue-specific isoforms. Febs Letters. 397: 55-60. PMID 8941713 DOI: 10.1016/S0014-5793(96)01140-4 |
0.554 |
|
| 1991 |
Ryazanov AG, Rudkin BB, Spirin AS. Regulation of protein synthesis at the elongation stage. New insights into the control of gene expression in eukaryotes. Febs Letters. 285: 170-5. PMID 1855586 DOI: 10.1016/0014-5793(91)80798-8 |
0.429 |
|
| 1990 |
Celis JE, Madsen P, Ryazanov AG. Increased phosphorylation of elongation factor 2 during mitosis in transformed human amnion cells correlates with a decreased rate of protein synthesis. Proceedings of the National Academy of Sciences of the United States of America. 87: 4231-5. PMID 2349232 DOI: 10.1073/pnas.87.11.4231 |
0.304 |
|
| 1989 |
Koizumi S, Ryazanov A, Hama T, Chen HC, Guroff G. Identification of Nsp100 as elongation factor 2 (EF-2). Febs Letters. 253: 55-8. PMID 2759242 DOI: 10.1016/0014-5793(89)80928-7 |
0.518 |
|
| 1989 |
Ryazanov AG, Davydova EK. Mechanism of elongation factor 2 (EF-2) inactivation upon phosphorylation. Phosphorylated EF-2 is unable to catalyze translocation. Febs Letters. 251: 187-90. PMID 2753158 DOI: 10.1016/0014-5793(89)81452-8 |
0.539 |
|
| 1988 |
Ryazanov AG, Shestakova EA, Natapov PG. Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation. Nature. 334: 170-3. PMID 3386756 DOI: 10.1038/334170A0 |
0.582 |
|
| 1988 |
Sitikov AS, Simonenko PN, Shestakova EA, Ryazanov AG, Ovchinnikov LP. cAMP-dependent activation of protein synthesis correlates with dephosphorylation of elongation factor 2. Febs Letters. 228: 327-31. PMID 2830143 DOI: 10.1016/0014-5793(88)80025-5 |
0.455 |
|
| 1988 |
Ryazanov AG, Natapov PG, Shestakova EA, Severin FF, Spirin AS. Phosphorylation of the elongation factor 2: the fifth Ca2+/calmodulin-dependent system of protein phosphorylation. Biochimie. 70: 619-26. PMID 2458772 DOI: 10.1016/0300-9084(88)90245-3 |
0.492 |
|
| 1987 |
Ryazanov AG. Ca2+/calmodulin-dependent phosphorylation of elongation factor 2. Febs Letters. 214: 331-4. PMID 3569528 DOI: 10.1016/0014-5793(87)80081-9 |
0.409 |
|
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