Ernesto L. Schiffrin - Publications

Affiliations: 
Université de Montréal, Montréal, Canada 
Area:
Cell Biology, Animal Physiology Biology, Pathology

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Year Citation  Score
2020 Higaki A, Mahmoud AUM, Paradis P, Schiffrin EL. Role of Interleukin-23/Interleukin-17 Axis in T-Cell Mediated Actions in Hypertension. Cardiovascular Research. PMID 32870976 DOI: 10.1093/Cvr/Cvaa257  0.306
2020 Ferreira NS, Tostes RC, Paradis P, Schiffrin EL. Aldosterone, Inflammation, Immune System and Hypertension. American Journal of Hypertension. PMID 32820797 DOI: 10.1093/Ajh/Hpaa137  0.369
2020 Zanoli L, Briet M, Empana JP, Cunha PG, Mäki-Petäjä KM, Protogerou AD, Tedgui A, Touyz RM, Schiffrin EL, Spronck B, Bouchard P, Vlachopoulos C, Bruno RM, Boutouyrie P. Vascular consequences of inflammation: a position statement from the ESH Working Group on Vascular Structure and Function and the ARTERY Society. Journal of Hypertension. PMID 32649623 DOI: 10.1097/Hjh.0000000000002508  0.374
2020 Ouerd S, Idris-Khodja N, Trindade M, Ferreira NS, Berillo O, Coelho SC, Neves MF, Jandeleit-Dahm KA, Paradis P, Schiffrin EL. ENDOTHELIUM-RESTRICTED ENDOTHELIN-1 OVEREXPRESSION IN TYPE-1 DIABETES WORSENS ATHEROSCLEROSIS AND IMMUNE CELL INFILTRATION VIA NOX1. Cardiovascular Research. PMID 32533834 DOI: 10.1093/Cvr/Cvaa168  0.312
2020 Schiffrin EL. Estrogen receptors and T cells determine how sex affects aldosterone-induced hypertension. Cardiovascular Research. PMID 32533825 DOI: 10.1093/Cvr/Cvaa170  0.372
2020 Schiffrin EL. How Structure, Mechanics, and Function of the Vasculature Contribute to Blood Pressure Elevation in Hypertension. The Canadian Journal of Cardiology. 36: 648-658. PMID 32389338 DOI: 10.1016/J.Cjca.2020.02.003  0.47
2020 Rabi DM, McBrien KA, Sapir-Pichhadze R, Nakhla M, Ahmed SB, Dumanski SM, Butalia S, Leung AA, Harris KC, Cloutier L, Zarnke KB, Ruzicka M, Hiremath S, Feldman RD, Tobe SW, ... ... Schiffrin EL, et al. Hypertension Canada's 2020 Comprehensive Guidelines for the Prevention, Diagnosis, Risk Assessment, and Treatment of Hypertension in Adults and Children. The Canadian Journal of Cardiology. 36: 596-624. PMID 32389335 DOI: 10.1016/J.Cjca.2020.02.086  0.333
2020 Touyz RM, Feldman RD, Harrison DG, Schiffrin EL. A New Look At the Mosaic Theory of Hypertension. The Canadian Journal of Cardiology. 36: 591-592. PMID 32389334 DOI: 10.1016/J.Cjca.2020.03.025  0.313
2020 Schiffrin EL, Flack J, Ito S, Muntner P, Webb C. Hypertension and COVID-19. American Journal of Hypertension. PMID 32251498 DOI: 10.1093/Ajh/Hpaa057  0.427
2020 Berillo O, Huo KG, Fraulob-Aquino JC, Richer C, Briet M, Boutouyrie P, Lipman ML, Sinnett D, Paradis P, Schiffrin EL. Circulating let-7g-5p and miR-191-5p are independent predictors of chronic kidney disease in hypertensive patients. American Journal of Hypertension. PMID 32115655 DOI: 10.1093/Ajh/Hpaa031  0.362
2019 Grunewald ZI, Jurrissen TJ, Woodford ML, Ramirez-Perez FI, Park LK, Pettit-Mee R, Ghiarone T, Brown SM, Morales-Quinones M, Ball JR, Staveley-O'Carroll KF, Aroor AR, Fadel PJ, Paradis P, Schiffrin EL, et al. Chronic Elevation of Endothelin-1 Alone May Not Be Sufficient to Impair Endothelium-Dependent Relaxation. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11913. PMID 31630572 DOI: 10.1161/Hypertensionaha.119.13676  0.366
2019 Schiffrin EL, Engert JC. Periodontitis and hypertension: causally linked by immune mechanisms. European Heart Journal. PMID 31589300 DOI: 10.1093/Eurheartj/Ehz729  0.324
2019 Khan N, Bell A, Berg A, Campbell N, Kaczorowski J, Rabi D, Schiffrin EL, Tsuyuki RT. A call to action to implement prescribing authority to pharmacists for hypertension management. Canadian Pharmacists Journal : Cpj = Revue Des Pharmaciens Du Canada : Rpc. 152: 285-287. PMID 31534583 DOI: 10.1177/1715163519866144  0.316
2019 Carcel C, Neal B, Oparil S, Rogers K, Narkiewicz K, Wang JG, Schiffrin EL, Poulter N, Azizi M, Chalmers J. Clinical characteristics, antihypertensive medication use and blood pressure control among patients with treatment-resistant hypertension: the Survey of PatIents with treatment ResIstant hyperTension study. Journal of Hypertension. PMID 31415307 DOI: 10.1097/Hjh.0000000000002184  0.351
2019 Zack R, Okunade O, Olson E, Salt M, Amodeo C, Anchala R, Berwanger O, Campbell N, Chia YC, Damasceno A, Phuong Do TN, Tamdja Dzudie A, Fiuza M, Mirza F, Nitsch D, ... ... Schiffrin EL, et al. Improving Hypertension Outcome Measurement in Low- and Middle-Income Countries. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11811. PMID 30929516 DOI: 10.1161/Hypertensionaha.118.11916  0.309
2019 Huo KG, Richer C, Berillo O, Mahjoub N, Fraulob-Aquino JC, Barhoumi T, Ouerd S, Coelho SC, Sinnett D, Paradis P, Schiffrin EL. miR-431-5p Knockdown Protects Against Angiotensin II-Induced Hypertension and Vascular Injury. Hypertension (Dallas, Tex. : 1979). 73: 1007-1017. PMID 30929512 DOI: 10.1161/Hypertensionaha.119.12619  0.416
2019 Higaki A, Caillon A, Paradis P, Schiffrin EL. Innate and Innate-Like Immune System in Hypertension and Vascular Injury. Current Hypertension Reports. 21: 4. PMID 30659373 DOI: 10.1007/S11906-019-0907-1  0.334
2019 Schiffrin EL. New blood pressure cut-offs, prevalence of hypertension and control, and mood disorders: are patients benefitting from lower cut-offs for defining hypertension? European Heart Journal. PMID 30624628 DOI: 10.1093/Eurheartj/Ehy891  0.38
2019 Iulita MF, Duchemin S, Vallerand D, Barhoumi T, Alvarez F, Istomine R, Laurent C, Youwakim J, Paradis P, Arbour N, Piccirillo CA, Schiffrin EL, Girouard H. CD4 Regulatory T Lymphocytes Prevent Impaired Cerebral Blood Flow in Angiotensin II-Induced Hypertension. Journal of the American Heart Association. 8: e009372. PMID 30572753 DOI: 10.1161/Jaha.118.009372  0.425
2019 Paradis P, Mahjoub N, Huo K, Berillo O, Richer C, Fraulob-Aquino JC, Rehman A, Briet M, Boutouyrie P, Lipman ML, Sinnett D, Schiffrin EL. Abstract P3003: miR-338-3p Down-Regulation Caused Up-Regulation of Alkaline Ceramidase 2 and Glutathione Peroxidase 3 mRNAs in Subcutaneous Small Arteries of Hypertensive Patients With Chronic Kidney Disease Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.P3003  0.314
2019 Berillo O, Ouerd S, Huo K, Rehman A, Richer C, Sinnett D, Kwitek AE, Paradis P, Schiffrin EL. Abstract P150: Genes of a Brown Norway Chromosome 2 Fragment Introgressed Into Hypertensive Dahl Salt-Sensitive Background Exert Pro-Inflammatory Effects When Stimulated by a High-Salt Diet Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.P150  0.314
2019 Shokoples B, Paradis P, Schiffrin EL. Abstract P1113: P2x7 Receptor Plays a Role in Angiotensin II-Induced Hypertension and Vascular Remodeling Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.P1113  0.477
2019 Mahmoud A, Caillon A, Paradis P, Schiffrin EL. Abstract 126: Role of V γ6 + γδ T Cells in Angiotensin Il-Induced Hypertension and Vascular Injury Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.126  0.363
2019 Caillon A, Paradis P, Schiffrin EL. Abstract 023: γδ T Cells Mediate αβ T Cell Activation in Angiotensin II-Induced Hypertension Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.023  0.369
2019 Berillo O, Mahjoub N, Coelho SC, Mahmoud A, Offermanns S, Paradis P, Schiffrin EL. Abstract 008: Aldosterone Contributes to the Blood Pressure Elevation, Endothelial Dysfunction, and Norepinephrine Sensitivity Caused by Endothelial Human Endothelin-1 Overexpression in Mice Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.008  0.397
2018 Calhoun DA, Schiffrin EL, Flack JM. Resistant Hypertension: An Update. American Journal of Hypertension. PMID 30407514 DOI: 10.1093/Ajh/Hpy156  0.346
2018 Caillon A, Paradis P, Schiffrin EL. Role of Immune Cells in Hypertension. British Journal of Pharmacology. PMID 29952002 DOI: 10.1111/Bph.14427  0.358
2018 Nerenberg KA, Zarnke KB, Leung AA, Dasgupta K, Butalia S, McBrien K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, ... ... Schiffrin EL, et al. Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children. The Canadian Journal of Cardiology. 34: 506-525. PMID 29731013 DOI: 10.1016/J.Cjca.2018.02.022  0.407
2018 Daskalopoulou SS, Rabi DM, Schiffrin EL, Feldman RD, Padwal RS, Tremblay G, Khan NA. Hypertension Guidelines in the United States and Canada: Are We Getting Closer? Hypertension (Dallas, Tex. : 1979). PMID 29686013 DOI: 10.1161/Hypertensionaha.117.10772  0.39
2018 Cerrato R, Crabtree M, Antoniades C, Kublickiene K, Schiffrin EL, Channon KM, Böhm F. Effects Of Endothelin-1 On Intracellular Tetrahydrobiopterin Levels In Vascular Tissue. Scandinavian Cardiovascular Journal : Scj. 1-7. PMID 29566572 DOI: 10.1080/14017431.2018.1453942  0.303
2018 Schiffrin EL. Global Impact of the 2017 American College of Cardiology/American Heart Association Hypertension Guidelines: A Perspective From Canada. Circulation. 137: 883-885. PMID 29483168 DOI: 10.1161/Circulationaha.117.032849  0.396
2018 Schiffrin EL. A Genetic Variant Associated with the Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression. Nephron. PMID 29448245 DOI: 10.1159/000487346  0.396
2018 Schiffrin EL. Hypertension in 2017: Novel mechanisms of hypertension and vascular dysfunction. Nature Reviews. Nephrology. PMID 29292372 DOI: 10.1038/Nrneph.2017.178  0.411
2018 Berillo O, Ouerd S, Huo K, Rehman A, Richer C, Sinnett D, Kwitek AE, Paradis P, Schiffrin EL. Abstract P223: Identification of Chromosome 2 Differentially Expressed Genes Linked to Vascular Inflammation Using Congenic Rats Fed a Normal and High-Salt Diet Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P223  0.387
2018 Berillo O, Coelho SC, Mahjoub N, Ferreira N, Offermanns S, Paradis P, Schiffrin EL. Abstract P116: Induction of Human Endothelin-1 Overexpression for 3 Months Increases Plasma Aldosterone Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P116  0.357
2018 Paradis P, Huo K, Richer C, Fraulob-Aquino J, Rehman A, Briet M, Boutouyrie P, Lipman ML, Sinnett D, Schiffrin EL. A2935 microRNA profiling in peripheral blood mononuclear cells from hypertensive patients with or without chronic kidney disease Journal of Hypertension. 36: e21. DOI: 10.1097/01.Hjh.0000548071.11661.6D  0.333
2018 Paradis P, Huo K, Richer C, Fraulob-Aquino J, Barhoumi T, Ouerd S, Coelho SC, Sinnett D, Schiffrin EL. A2921 In vivo miR-431–5p knockdown protects against angiotensin II-induced hypertension and vascular injury Journal of Hypertension. 36: e21. DOI: 10.1097/01.Hjh.0000548070.04038.1A  0.354
2017 Flack JM, Calhoun D, Schiffrin EL. The New ACC/AHA Hypertension Guidelines for the prevention, detection, evaluation, and management of high blood pressure in adults. American Journal of Hypertension. PMID 29228096 DOI: 10.1093/Ajh/Hpx207  0.346
2017 Schiffrin EL. The Year in Clinical Hypertension from other pages. American Journal of Hypertension. PMID 29186309 DOI: 10.1093/Ajh/Hpx206  0.334
2017 Caillon A, Huo KG, Paradis P, Schiffrin EL. Response by Caillon et al to Letter Regarding Article, "γδ T Cells Mediate Angiotensin II-Induced Hypertension and Vascular Injury". Circulation. 136: 2200-2201. PMID 29180499 DOI: 10.1161/Circulationaha.117.030517  0.447
2017 Coelho SC, Berillo O, Caillon A, Ouerd S, Fraulob-Aquino JC, Barhoumi T, Offermanns S, Paradis P, Schiffrin EL. Three-Month Endothelial Human Endothelin-1 Overexpression Causes Blood Pressure Elevation and Vascular and Kidney Injury. Hypertension (Dallas, Tex. : 1979). PMID 29133362 DOI: 10.1161/Hypertensionaha.117.09925  0.407
2017 Barhoumi T, Fraulob-Aquino JC, Mian MOR, Ouerd S, Idris-Khodja N, Huo KG, Rehman A, Caillon A, Dancose-Giambattisto B, Ebrahimian T, Lehoux S, Paradis P, Schiffrin EL. Matrix metalloproteinase-2 knockout prevents angiotensin II-induced vascular injury. Cardiovascular Research. PMID 29016715 DOI: 10.1093/Cvr/Cvx115  0.385
2017 Kline GA, Prebtani APH, Leung AA, Schiffrin EL. The Potential Role of Primary Care in Case Detection/Screening of Primary Aldosteronism. American Journal of Hypertension. PMID 28992276 DOI: 10.1093/Ajh/Hpx064  0.337
2017 Kline GA, Prebtani APH, Leung AA, Schiffrin EL. Primary aldosteronism: a common cause of resistant hypertension. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 189: E773-E778. PMID 28584041 DOI: 10.1503/Cmaj.161486  0.374
2017 Leung AA, Daskalopoulou SS, Dasgupta K, McBrien K, Butalia S, Zarnke KB, Nerenberg K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, ... ... Schiffrin EL, et al. Hypertension Canada's 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults. The Canadian Journal of Cardiology. 33: 557-576. PMID 28449828 DOI: 10.1016/J.Cjca.2017.03.005  0.415
2017 Caillon A, Mian MO, Fraulob-Aquino JC, Huo KG, Barhoumi T, Ouerd S, Sinnaeve PR, Paradis P, Schiffrin EL. Gamma Delta T Cells Mediate Angiotensin II-Induced Hypertension and Vascular Injury. Circulation. PMID 28330983 DOI: 10.1161/Circulationaha.116.027058  0.401
2017 Idris-Khodja N, Ouerd S, Trindade M, Gornitsky J, Rehman A, Barhoumi T, Offermanns S, Gonzalez FJ, Neves MF, Paradis P, Schiffrin EL. Vascular smooth muscle cell peroxisome proliferator-activated receptor γ protects against endothelin-1-induced oxidative stress and inflammation. Journal of Hypertension. PMID 28234672 DOI: 10.1097/Hjh.0000000000001324  0.405
2017 Rautureau Y, Paradis P, Schiffrin EL. Generation of a Mouse Model with Smooth Muscle Cell Specific Loss of the Expression of PPARγ. Methods in Molecular Biology (Clifton, N.J.). 1527: 381-407. PMID 28116732 DOI: 10.1007/978-1-4939-6625-7_30  0.355
2016 Paradis P, Coelho SC, Ouerd S, Fraulob-Aquino JC, Offermanns S, Schiffrin EL. OS 21-06 THREE-MONTH EXPOSURE TO ENDOTHELIN-1 OVEREXPRESSION INCREASES BLOOD PRESSURE AND CAUSES SMALL ARTERY INJURY. Journal of Hypertension. 34: e236. PMID 27643026 DOI: 10.1097/01.Hjh.0000500525.81457.38  0.383
2016 Paradis P, Ouerd S, Idris-Khodja N, Trindade M, Coelho SC, Jandeleit-Dahm KA, Schiffrin EL. OS 21-01 NOX1 OR NOX4 DELETION PREVENTS TYPE 1 DIABETES-INDUCED ENDOTHELIAL DYSFUNCTION. Journal of Hypertension. 34: e235. PMID 27643021 DOI: 10.1097/01.Hjh.0000500520.50963.97  0.321
2016 Paradis P, Barhoumi T, Mian MO, Fraulob-Aquino JC, Rehman A, Idris-Khodja N, Schiffrin EL. OS 15-02 MATRIX METALLOPROTEINASE 2 KNOCKOUT PROTECTS FROM ANGIOTENSIN II-INDUCED VASCULAR INJURY IN PART VIA INHIBITION OF EGFR AND ERK1/2 ACTIVATION. Journal of Hypertension. 34: e215. PMID 27642974 DOI: 10.1097/01.Hjh.0000500469.76512.2B  0.388
2016 Campbell NR, Lackland DT, Niebylski ML, Orias M, Redburn KA, Nilsson PM, Zhang XH, Burrell L, Horiuchi M, Poulter NR, Prabhakaran D, Ramirez AJ, Schiffrin EL, Schutte AE, Touyz RM, et al. 2016 Dietary Salt Fact Sheet and Call to Action: The World Hypertension League, International Society of Hypertension, and the International Council of Cardiovascular Prevention and Rehabilitation. Journal of Clinical Hypertension (Greenwich, Conn.). PMID 27515460 DOI: 10.1111/Jch.12894  0.403
2016 Idris-Khodja N, Ouerd S, Mian MO, Gornitsky J, Barhoumi T, Paradis P, Schiffrin EL. Endothelin-1 Overexpression Exaggerates Diabetes-Induced Endothelial Dysfunction by Altering Oxidative Stress. American Journal of Hypertension. PMID 27465439 DOI: 10.1093/Ajh/Hpw078  0.315
2016 Schiffrin EL, Campbell NR, Feldman RD, Kaczorowski J, Lewanczuk R, Padwal R, Tobe SW. Hypertension in Canada: Past, Present, and Future. Annals of Global Health. 82: 288-299. PMID 27372532 DOI: 10.1016/J.Aogh.2016.02.006  0.424
2016 Weber MA, Poulter NR, Schutte AE, Burrell LM, Horiuchi M, Prabhakaran D, Ramirez AJ, Wang JG, Schiffrin EL, Touyz RM. Is It Time to Reappraise Blood Pressure Thresholds and Targets? A Statement From the International Society of Hypertension-A Global Perspective. Hypertension. PMID 27354426 DOI: 10.1161/Hypertensionaha.116.07818  0.395
2016 Schiffrin EL, Calhoun DA, Flack JM. Do We Need a New Definition of Hypertension After SPRINT? American Journal of Hypertension. PMID 27334926 DOI: 10.1093/Ajh/Hpw068  0.367
2016 Campbell NR, Khalsa T, Lackland DT, Niebylski ML, Nilsson PM, Redburn KA, Orias M, Zhang XH, Burrell L, Horiuchi M, Poulter NR, Prabhakaran D, Ramirez AJ, ... Schiffrin EL, et al. High Blood Pressure 2016: Why Prevention and Control Are Urgent and Important. The World Hypertension League, International Society of Hypertension, World Stroke Organization, International Diabetes Foundation, International Council of Cardiovascular Prevention and Rehabilitation, International Society of Nephrology. Journal of Clinical Hypertension (Greenwich, Conn.). PMID 27316336 DOI: 10.1111/Jch.12840  0.369
2016 Padwal R, Rabi DM, Schiffrin EL. Recommendations for Intensive Blood Pressure Lowering in High-Risk Patients, the Canadian Viewpoint. Hypertension. 68: 3-5. PMID 27160203 DOI: 10.1161/Hypertensionaha.116.07573  0.363
2016 Leung AA, Nerenberg K, Daskalopoulou SS, McBrien K, Zarnke KB, Dasgupta K, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Tobe SW, Ruzicka M, ... ... Schiffrin EL, et al. Hypertension Canada's 2016 Canadian Hypertension Education Program Guidelines for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension. The Canadian Journal of Cardiology. 32: 569-88. PMID 27118291 DOI: 10.1016/J.Cjca.2016.02.066  0.407
2016 Briet M, Barhoumi T, Mian MO, Coelho SC, Ouerd S, Rautureau Y, Coffman TM, Paradis P, Schiffrin EL. Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors. Hypertension. 67: 897-905. PMID 27045029 DOI: 10.1161/Hypertensionaha.115.07074  0.403
2016 Bertagnolli M, Dios A, Béland-Bonenfant S, Gascon G, Sutherland M, Lukaszewski MA, Cloutier A, Paradis P, Schiffrin EL, Nuyt AM. Activation of the Cardiac Renin-Angiotensin System in High Oxygen-Exposed Newborn Rats: Angiotensin Receptor Blockade Prevents the Developmental Programming of Cardiac Dysfunction. Hypertension. 67: 774-82. PMID 26857347 DOI: 10.1161/Hypertensionaha.115.06745  0.363
2016 Caillon A, Schiffrin EL. Role of Inflammation and Immunity in Hypertension: Recent Epidemiological, Laboratory, and Clinical Evidence. Current Hypertension Reports. 18: 21. PMID 26846785 DOI: 10.1007/S11906-016-0628-7  0.371
2016 Schiffrin EL, Calhoun DA, Flack JM, Ito S, Webb RC. A Message From the New Editorial Team at the American Journal of Hypertension. American Journal of Hypertension. 29: 1. PMID 26658829 DOI: 10.1093/Ajh/Hpv173  0.33
2016 Mian MO, Barhoumi T, Briet M, Paradis P, Schiffrin EL. Deficiency of T-regulatory cells exaggerates angiotensin II-induced microvascular injury by enhancing immune responses. Journal of Hypertension. 34: 97-108. PMID 26630215 DOI: 10.1097/Hjh.0000000000000761  0.369
2016 Ouerd S, Idris-Khodja N, Trindade M, Gornitsky J, Rehman A, Offermanns S, Gonzalez F, Barhoumi T, Paradis P, Schiffrin E. MPS 18-02 ENDOTHELIN-1 OVEREXPRESSION PRESERVES ENDOTHELIAL FUNCTION IN MICE WITH VASCULAR SMOOTH MUSCLE CELL-SPECIFIC DELETION OF PPAR-GAMMA Journal of Hypertension. 34: e423. DOI: 10.1097/01.Hjh.0000501088.36686.4B  0.324
2016 Schiffrin E. SY 15-1 MECHANISM OF ENDOTHELIN-1 REGULATION IN HYPERTENSION Journal of Hypertension. 34: e371. DOI: 10.1097/01.Hjh.0000500955.33596.Eb  0.393
2016 Caillon A, Mian MOR, Fraulob-Aquino JC, Huo K, Barhoumi T, Paradis P, Schiffrin EL. PS 07-28 GAMMA/DELTA T CELLS MEDIATE ANGIOTENSIN II-INDUCED HYPERTENSION AND VASCULAR INJURY Journal of Hypertension. 34: e290. DOI: 10.1097/01.Hjh.0000500691.28985.B4  0.415
2016 Paradis P, Briet M, Barhoumi T, Mian MOR, Coelho SC, Rautureau Y, Coffman TM, Schiffrin EL. PS 07-16 CROSSTALK BETWEEN ALDOSTERONE-STIMULATED MINERALOCORTICOID RECEPTOR AND ANGIOTENSIN RECEPTOR PATHWAYS PLAYS A ROLE IN ALDOSTERONE-INDUCED VASCULAR INJURY Journal of Hypertension. 34: e287-e288. DOI: 10.1097/01.Hjh.0000500680.24040.E2  0.431
2016 Schiffrin E. SP 02-5 DO WE NEED A NEW DEFINITION OF HYPERTENSION? Journal of Hypertension. 34: e194. DOI: 10.1097/01.Hjh.0000500424.95537.4D  0.325
2016 Paradis P, Huo K, Barhoumi T, Fraulob-Aquino JC, Richer C, Lajoie M, Sinnett D, Schiffrin EL. MPS 01-01 A CONSERVED microRNA CLUSTER AS A POTENTIAL MASTER GENE EXPRESSION REGULATOR IN ANGIOTENSIN II-INDUCED VASCULAR DAMAGE Journal of Hypertension. 34: e78. DOI: 10.1097/01.Hjh.0000500055.51324.8F  0.343
2015 Schiffrin EL. Mechanisms of remodelling of small arteries, antihypertensive therapy and the immune system in hypertension. Clinical and Investigative Medicine. MéDecine Clinique Et Experimentale. 38: E394-402. PMID 26654522 DOI: 10.25011/Cim.V38I6.26202  0.443
2015 Townsend RR, Wilkinson IB, Schiffrin EL, Avolio AP, Chirinos JA, Cockcroft JR, Heffernan KS, Lakatta EG, McEniery CM, Mitchell GF, Najjar SS, Nichols WW, Urbina EM, Weber T. Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness: A Scientific Statement From the American Heart Association. Hypertension. 66: 698-722. PMID 26160955 DOI: 10.1161/Hyp.0000000000000033  0.322
2015 Rautureau Y, Coelho SC, Fraulob-Aquino JC, Huo KG, Rehman A, Offermanns S, Paradis P, Schiffrin EL. Inducible Human Endothelin-1 Overexpression in Endothelium Raises Blood Pressure via Endothelin Type A Receptors. Hypertension. PMID 26101346 DOI: 10.1161/Hypertensionaha.115.05168  0.392
2015 Daskalopoulou SS, Rabi DM, Zarnke KB, Dasgupta K, Nerenberg K, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, McKay DW, Tremblay G, McLean D, Tobe SW, Ruzicka M, ... ... Schiffrin EL, et al. The 2015 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. The Canadian Journal of Cardiology. 31: 549-68. PMID 25936483 DOI: 10.1016/J.Cjca.2015.02.016  0.391
2015 Blom KC, Farina S, Gomez YH, Campbell NR, Hemmelgarn BR, Cloutier L, McKay DW, Dawes M, Tobe SW, Bolli P, Gelfer M, McLean D, Bartlett G, Joseph L, Featherstone R, ... Schiffrin EL, et al. MEthods of ASsessing blood pressUre: identifying thReshold and target valuEs (MeasureBP): a review & study protocol. Current Hypertension Reports. 17: 533. PMID 25790798 DOI: 10.1007/S11906-015-0533-5  0.305
2015 Ferrario CM, Schiffrin EL. Role of mineralocorticoid receptor antagonists in cardiovascular disease. Circulation Research. 116: 206-13. PMID 25552697 DOI: 10.1161/Circresaha.116.302706  0.407
2015 Perry CG, Marie Freel E, O'Dwyer P, Schiffrin EL, Jennings GL, Dominiczak AF, De Buyzere M. Rare cause of severe hypertension in a young woman Hypertension. 65: 21-24. PMID 25385763 DOI: 10.1161/Hypertensionaha.114.04619  0.391
2014 Davis M, Schiffrin EL, Joyal D. Renal denervation therapy for resistant hypertension. Current Treatment Options in Cardiovascular Medicine. 16: 350. PMID 25300359 DOI: 10.1007/S11936-014-0350-1  0.372
2014 Mark PB, Schiffrin EL, Jennings GL, Dominiczak AF, Wang JG, De Buyzere M, Staessen JA. Renovascular hypertension: to stent or not to stent? Hypertension. 64: 1165-8. PMID 25245390 DOI: 10.1161/Hypertensionaha.114.04497  0.333
2014 Freel EM, Perry CG, O'Dwyer P, Staessen JA, Jennings GL, Granger JP, De Buyzere M, Schiffrin EL. An unusual cause of mineralocorticoid hypertension. Hypertension. 64: 689-92. PMID 25156173 DOI: 10.1161/Hypertensionaha.114.04401  0.334
2014 Idris-Khodja N, Mian MO, Paradis P, Schiffrin EL. Dual opposing roles of adaptive immunity in hypertension. European Heart Journal. 35: 1238-44. PMID 24685711 DOI: 10.1093/Eurheartj/Ehu119  0.342
2014 Schiffrin EL. Optimum blood pressure target after lacunar stroke: con side of the argument. Hypertension. 63: 923-4. PMID 24591334 DOI: 10.1161/Hypertensionaha.113.02529  0.302
2014 Barhoumi T, Briet M, Kasal DA, Fraulob-Aquino JC, Idris-Khodja N, Laurant P, Paradis P, Schiffrin EL. Erythropoietin-induced hypertension and vascular injury in mice overexpressing human endothelin-1: exercise attenuated hypertension, oxidative stress, inflammation and immune response. Journal of Hypertension. 32: 784-94. PMID 24463938 DOI: 10.1097/Hjh.0000000000000101  0.416
2014 Campbell NRC, Lackland DT, Chockalingam A, Lisheng L, Harrap SB, Touyz RM, Burrell LM, Ramírez AJ, Schmieder RE, Schutte AE, Prabhakaran D, Schiffrin EL. The International Society of Hypertension and World Hypertension League call on governments, nongovernmental organizations and the food industry to work to reduce dietary sodium. Journal of Hypertension. 32: 446-447. PMID 24430121 DOI: 10.1097/Hjh.0000000000000079  0.387
2014 Schiffrin EL. Inflammation, immunity and development of essential hypertension. Journal of Hypertension. 32: 228-9. PMID 24430118 DOI: 10.1097/Hjh.0000000000000042  0.332
2014 Campbell N, Lackland D, Chockalingam A, Lisheng L, Schiffrin EL, Harrap S, Touyz RM, Burrell L, Ramírez A, Schmieder R, Aletta S, Prabhakaran D. The World Hypertension League and International Society of Hypertension Call on Governments, Nongovernmental Organizations, and the Food Industry to Work to Reduce Dietary Sodium Journal of Clinical Hypertension. 16: 99-100. PMID 24422889 DOI: 10.1111/Jch.12245  0.334
2014 Mian MO, Paradis P, Schiffrin EL. Innate immunity in hypertension. Current Hypertension Reports. 16: 413. PMID 24407446 DOI: 10.1007/S11906-013-0413-9  0.347
2014 Weber MA, Schiffrin EL, White WB, Mann S, Lindholm LH, Kenerson JG, Flack JM, Carter BL, Materson BJ, Ram CV, Cohen DL, Cadet JC, Jean-Charles RR, Taler S, Kountz D, et al. Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. Journal of Clinical Hypertension (Greenwich, Conn.). 16: 14-26. PMID 24341872 DOI: 10.1111/Jch.12237  0.347
2014 Weber MA, Schiffrin EL, White WB, Mann S, Lindholm LH, Kenerson JG, Flack JM, Carter BL, Materson BJ, Ram CV, Cohen DL, Cadet JC, Jean-Charles RR, Taler S, Kountz D, et al. Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of Hypertension. Journal of Hypertension. 32: 3-15. PMID 24270181 DOI: 10.1097/Hjh.0000000000000065  0.347
2014 Bertagnolli M, Huyard F, Cloutier A, Anstey Z, Huot-Marchand JÉ, Fallaha C, Paradis P, Schiffrin EL, Deblois D, Nuyt AM. Transient neonatal high oxygen exposure leads to early adult cardiac dysfunction, remodeling, and activation of the renin-angiotensin system. Hypertension. 63: 143-50. PMID 24166752 DOI: 10.1161/Hypertensionaha.113.01760  0.405
2014 Schiffrin EL. Immune mechanisms in hypertension and vascular injury. Clinical Science (London, England : 1979). 126: 267-74. PMID 24144355 DOI: 10.1042/Cs20130407  0.435
2013 Mian MO, Idris-Khodja N, Li MW, Leibowitz A, Paradis P, Rautureau Y, Schiffrin EL. Preservation of endothelium-dependent relaxation in atherosclerotic mice with endothelium-restricted endothelin-1 overexpression. The Journal of Pharmacology and Experimental Therapeutics. 347: 30-7. PMID 23902937 DOI: 10.1124/Jpet.113.206532  0.329
2013 Javeshghani D, Barhoumi T, Idris-Khodja N, Paradis P, Schiffrin EL. Reduced macrophage-dependent inflammation improves endothelin-1-induced vascular injury. Hypertension. 62: 112-7. PMID 23670300 DOI: 10.1161/Hypertensionaha.113.01298  0.345
2013 Davis MI, Filion KB, Zhang D, Eisenberg MJ, Afilalo J, Schiffrin EL, Joyal D. Effectiveness of renal denervation therapy for resistant hypertension: a systematic review and meta-analysis. Journal of the American College of Cardiology. 62: 231-41. PMID 23644092 DOI: 10.1016/J.Jacc.2013.04.010  0.352
2013 Briet M, Barhoumi T, Mian MO, Sierra C, Boutouyrie P, Davidman M, Bercovitch D, Nessim SJ, Frisch G, Paradis P, Lipman ML, Schiffrin EL. Effects of recombinant human erythropoietin on resistance artery endothelial function in stage 4 chronic kidney disease. Journal of the American Heart Association. 2: e000128. PMID 23584809 DOI: 10.1161/Jaha.113.000128  0.344
2013 Leibowitz A, Rehman A, Paradis P, Schiffrin EL. Role of T regulatory lymphocytes in the pathogenesis of high-fructose diet-induced metabolic syndrome. Hypertension. 61: 1316-21. PMID 23529169 DOI: 10.1161/Hypertensionaha.111.203521  0.319
2013 Sheppard RJ, Schiffrin EL. Inhibition of the renin-angiotensin system for lowering coronary artery disease risk. Current Opinion in Pharmacology. 13: 274-9. PMID 23523606 DOI: 10.1016/J.Coph.2013.03.001  0.348
2013 Schiffrin EL. Vascular mineralocorticoid receptors regulate blood pressure effects on myogenic tone and role in aging. Circulation Research. 112: 415-7. PMID 23371898 DOI: 10.1161/Circresaha.113.300883  0.485
2013 Marchesi C, Rehman A, Rautureau Y, Kasal DA, Briet M, Leibowitz A, Simeone SM, Ebrahimian T, Neves MF, Offermanns S, Gonzalez FJ, Paradis P, Schiffrin EL. Protective role of vascular smooth muscle cell PPARγ in angiotensin II-induced vascular disease. Cardiovascular Research. 97: 562-70. PMID 23250918 DOI: 10.1093/Cvr/Cvs362  0.424
2013 Briet M, Schiffrin EL. Treatment of arterial remodeling in essential hypertension. Current Hypertension Reports. 15: 3-9. PMID 23250721 DOI: 10.1007/S11906-012-0325-0  0.481
2013 Briet M, Schiffrin EL. Vascular actions of aldosterone. Journal of Vascular Research. 50: 89-99. PMID 23172373 DOI: 10.1159/000345243  0.448
2013 Schiffrin EL. The immune system: role in hypertension. The Canadian Journal of Cardiology. 29: 543-8. PMID 22902155 DOI: 10.1016/J.Cjca.2012.06.009  0.448
2013 Schiffrin EL. Definition & diagnosis of hypertension Hypertension. 6-14. DOI: 10.2217/Ebo.12.178  0.364
2013 Savoia C, Schiffrin EL. Hypertensive vascular disease Hypertension. 132-150. DOI: 10.2217/Ebo.12.172  0.413
2013 Rautureau Y, Schiffrin EL. Endothelin system: roles in hypertension Hypertension. 102-115. DOI: 10.2217/Ebo.12.169  0.428
2013 Alderman MH, Cifkova R, Cosentino F, Crea F, Ferri C, Grassi D, Lippi C, Croce G, Casale R, Broccoletti S, Valeri L, Desideri G, Kurtz TW, Laurent S, Lüscher TF, ... ... Schiffrin EL, et al. The Renin-Angiotensin System, Capri 2005 Annual Review of Physiology. 12: 91-108. DOI: 10.2165/00151642-200512020-00005  0.422
2013 Paradis P, Barhoumi T, Briet M, Kasal DA, Laurant P, Schiffrin EL. Erythropoietin induced blood pressure rise, vascular inflammation and oxidative stress in mice overexpressing human endothelin-1: Improvement by exercise Life Sciences. 93: e29-e30. DOI: 10.1016/J.Lfs.2013.12.219  0.333
2013 Paradis P, Idris-Khodja N, Mian MOR, Li MW, Leibowitz A, Rautureau Y, Schiffrin EL. Remodeling of endothelial function in atherosclerotic mice overexpressing endothelin-1 restricted to endothelium Life Sciences. 93: e36. DOI: 10.1016/J.Lfs.2013.12.128  0.306
2012 Larochelle P, Kollmannsberger C, Feldman RD, Schiffrin EL, Poirier L, Patenaude F, Ruether D, Myers M, Bjarnason G. Hypertension management in patients with renal cell cancer treated with anti-angiogenic agents. Current Oncology (Toronto, Ont.). 19: 202-8. PMID 22876146 DOI: 10.3747/Co.19.972  0.408
2012 Kasal DA, Schiffrin EL. Angiotensin II, Aldosterone, and Anti-Inflammatory Lymphocytes: Interplay and Therapeutic Opportunities. International Journal of Hypertension. 2012: 829786. PMID 22685633 DOI: 10.1155/2012/829786  0.448
2012 Daskalopoulou SS, Khan NA, Quinn RR, Ruzicka M, McKay DW, Hackam DG, Rabkin SW, Rabi DM, Gilbert RE, Padwal RS, Dawes M, Touyz RM, Campbell TS, Cloutier L, Grover S, ... ... Schiffrin EL, et al. The 2012 Canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. The Canadian Journal of Cardiology. 28: 270-87. PMID 22595447 DOI: 10.1016/J.Cjca.2012.02.018  0.419
2012 Rautureau Y, Schiffrin EL. Endothelin in hypertension: an update. Current Opinion in Nephrology and Hypertension. 21: 128-36. PMID 22257795 DOI: 10.1097/Mnh.0B013E32834F0092  0.436
2012 Schiffrin EL. Effect of treatment on cardiac small resistance arteries in hypertension and diabetes: trick or treat. Journal of Hypertension. 30: 271-2. PMID 22236969 DOI: 10.1097/Hjh.0B013E32834Ea491  0.35
2012 Schiffrin EL. Vascular remodeling in hypertension: mechanisms and treatment. Hypertension. 59: 367-74. PMID 22203749 DOI: 10.1161/Hypertensionaha.111.187021  0.494
2012 Rehman A, Leibowitz A, Yamamoto N, Rautureau Y, Paradis P, Schiffrin EL. Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats. Hypertension. 59: 291-9. PMID 22184324 DOI: 10.1161/Hypertensionaha.111.180158  0.438
2012 Kasal DA, Barhoumi T, Li MW, Yamamoto N, Zdanovich E, Rehman A, Neves MF, Laurant P, Paradis P, Schiffrin EL. T regulatory lymphocytes prevent aldosterone-induced vascular injury. Hypertension. 59: 324-30. PMID 22146512 DOI: 10.1161/Hypertensionaha.111.181123  0.421
2012 Schiffrin EL. Immune modulation of resistance artery remodelling. Basic & Clinical Pharmacology & Toxicology. 110: 70-2. PMID 21740527 DOI: 10.1111/J.1742-7843.2011.00760.X  0.403
2012 Touyz RM, Savoia C, He Y, Endemann D, Pu Q, Ko EA, Deciuceis C, Montezano A, Schiffrin EL. Increased inflammatory biomarkers in hypertensive type 2 diabetic patients: improvement after angiotensin II type 1 receptor blockade. Journal of the American Society of Hypertension : Jash. 1: 189-99. PMID 20409851 DOI: 10.1016/J.Jash.2007.01.009  0.367
2012 Montezano AC, Amiri F, Tostes RC, Touyz RM, Schiffrin EL. Inhibitory effects of PPAR-gamma on endothelin-1-induced inflammatory pathways in vascular smooth muscle cells from normotensive and hypertensive rats. Journal of the American Society of Hypertension : Jash. 1: 150-60. PMID 20409845 DOI: 10.1016/J.Jash.2007.01.005  0.402
2012 Schiffrin EL. The vascular phenotypes in hypertension: Relation with the natural history of hypertension. Journal of the American Society of Hypertension : Jash. 1: 56-67. PMID 20409833 DOI: 10.1016/J.Jash.2006.11.003  0.46
2012 Paradis P, Barhoumi T, Briet M, Schiffrin EL. 414 ERYTHROPOIETIN-INDUCED HYPERTENSION AND VASCULAR INJURY IN MICE OVEREXPRESSING HUMAN ENDOTHELIN-1 WAS ATTENUATED BY EXERCISE Journal of Hypertension. 30: e122-e123. DOI: 10.1097/01.Hjh.0000420269.51013.8D  0.33
2012 Paradis P, Briet M, Mian MOR, Barhoumi T, Coffman TM, Schiffrin EL. 61 ALDOSTERONE-INDUCED SMALL ARTERY ENDOTHELIAL DYSFUNCTION, INFLAMMATION AND OXIDATIVE STRESS REQUIRES A FUNCTIONAL ANGIOTENSIN TYPE 1A RECEPTOR Journal of Hypertension. 30: e19. DOI: 10.1097/01.Hjh.0000419886.27496.A0  0.357
2012 Schiffrin EL. 60 IMMUNE MECHANISMS IN HYPERTENSION Journal of Hypertension. 30: e19. DOI: 10.1097/01.Hjh.0000419885.19873.A6  0.331
2012 Touyz RM, Schiffrin EL. Chapter 99 – Arterial Hypertension Musclefundamental Biology and Mechanisms of Disease. 1311-1319. DOI: 10.1016/B978-0-12-381510-1.00099-5  0.385
2012 Cloutier L, Schiffrin EL. Hypertension Prevalence and Control: Impact of Method of Blood Pressure Measurement Current Cardiovascular Risk Reports. 6: 267-273. DOI: 10.1007/S12170-012-0247-Z  0.353
2011 Leibowitz A, Schiffrin EL. Immune mechanisms in hypertension. Current Hypertension Reports. 13: 465-72. PMID 21842150 DOI: 10.1007/S11906-011-0224-9  0.396
2011 Rabi DM, Daskalopoulou SS, Padwal RS, Khan NA, Grover SA, Hackam DG, Myers MG, McKay DW, Quinn RR, Hemmelgarn BR, Cloutier L, Bolli P, Hill MD, Wilson T, Penner B, ... ... Schiffrin EL, et al. The 2011 Canadian Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. The Canadian Journal of Cardiology. 27: 415-433.e1-2. PMID 21801975 DOI: 10.1016/J.Cjca.2011.03.015  0.414
2011 Marchesi C, Essalmani R, Lemarié CA, Leibovitz E, Ebrahimian T, Paradis P, Seidah NG, Schiffrin EL, Prat A. Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy. Journal of Molecular Medicine (Berlin, Germany). 89: 1103-11. PMID 21681612 DOI: 10.1007/S00109-011-0776-9  0.375
2011 Callera GE, Yogi A, Briones AM, Montezano AC, He Y, Tostes RC, Schiffrin EL, Touyz RM. Vascular proinflammatory responses by aldosterone are mediated via c-Src trafficking to cholesterol-rich microdomains: role of PDGFR. Cardiovascular Research. 91: 720-31. PMID 21576132 DOI: 10.1093/Cvr/Cvr131  0.338
2011 Rautureau Y, Paradis P, Schiffrin EL. Cross-talk between aldosterone and angiotensin signaling in vascular smooth muscle cells. Steroids. 76: 834-9. PMID 21371487 DOI: 10.1016/J.Steroids.2011.02.015  0.436
2011 Sierra C, Coca A, Schiffrin EL. Vascular mechanisms in the pathogenesis of stroke. Current Hypertension Reports. 13: 200-7. PMID 21331606 DOI: 10.1007/S11906-011-0195-X  0.32
2011 Barhoumi T, Kasal DA, Li MW, Shbat L, Laurant P, Neves MF, Paradis P, Schiffrin EL. T regulatory lymphocytes prevent angiotensin II-induced hypertension and vascular injury. Hypertension. 57: 469-76. PMID 21263125 DOI: 10.1161/Hypertensionaha.110.162941  0.441
2011 Ebrahimian T, Li MW, Lemarié CA, Simeone SM, Pagano PJ, Gaestel M, Paradis P, Wassmann S, Schiffrin EL. Mitogen-activated protein kinase-activated protein kinase 2 in angiotensin II-induced inflammation and hypertension: regulation of oxidative stress. Hypertension. 57: 245-54. PMID 21173344 DOI: 10.1161/Hypertensionaha.110.159889  0.452
2011 Lemarié CA, Shbat L, Marchesi C, Angulo OJ, Deschênes ME, Blostein MD, Paradis P, Schiffrin EL. Mthfr deficiency induces endothelial progenitor cell senescence via uncoupling of eNOS and downregulation of SIRT1. American Journal of Physiology. Heart and Circulatory Physiology. 300: H745-53. PMID 21169404 DOI: 10.1152/Ajpheart.00321.2010  0.318
2011 Simeone SM, Li MW, Paradis P, Schiffrin EL. Vascular gene expression in mice overexpressing human endothelin-1 targeted to the endothelium. Physiological Genomics. 43: 148-60. PMID 21045115 DOI: 10.1152/Physiolgenomics.00218.2009  0.348
2011 Sierra C, Briet M, Edwards C, Boutouyrie P, Davidman M, Bercovitch D, Frisch G, Nessim SJ, Lipman ML, Schiffrin EL. EFFECT OF HEMODIALYSIS ON LARGE ARTERIES IN PATIENTS WITH INTRADIALYTIC HYPERTENSION Journal of Hypertension. 29: e74-e75. DOI: 10.1097/00004872-201106001-00188  0.38
2011 Briet M, Barhoumi T, Davidman M, Bercovitch D, Frisch G, Nessim SJ, Lipman ML, Schiffrin EL. RECOMBINANT HUMAN ERYTHROPOIETIN ALTERS SUBCUTANEOUS RESISTANCE ARTERY ENDOTHELIAL FUNCTION THROUGH A MECHANISM INVOLVING OXIDATIVE STRESS AND ENDOTHELIN-1 IN PATIENTS WITH STAGE 4 CHRONIC KIDNEY DISEASE Journal of Hypertension. 29: e10-e11. DOI: 10.1097/00004872-201106001-00029  0.319
2010 Ducharme A, Schiffrin EL. Reviewing the future of renin-angiotensin system blockade: the role of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in the prevention of atrial fibrillation. The Canadian Journal of Cardiology. 26: 21E-23E. PMID 21620287 DOI: 10.1016/S0828-282X(10)71170-3  0.347
2010 Schiffrin EL. Antioxidants in hypertension and cardiovascular disease. Molecular Interventions. 10: 354-62. PMID 21263161 DOI: 10.1124/Mi.10.6.4  0.351
2010 Grassi G, Schiffrin EL. Media-to-lumen ratio as predictor of renal abnormalities in hypertension: new findings, new questions. Journal of Hypertension. 28: 1811-3. PMID 20699714 DOI: 10.1097/Hjh.0B013E32833D7Fed  0.311
2010 Leenen FH, Schiffrin EL. Control rates of hypertension in North America. Hypertension. 56: 571-2. PMID 20696987 DOI: 10.1161/Hypertensionaha.110.157818  0.324
2010 Schiffrin EL. How are stressed prehypertensive rats pressured? Endothelin pleads guilty. Hypertension. 56: 191-2. PMID 20547969 DOI: 10.1161/Hypertensionaha.110.154013  0.42
2010 Rehman A, Schiffrin EL. Vascular effects of antihypertensive drug therapy. Current Hypertension Reports. 12: 226-32. PMID 20514556 DOI: 10.1007/S11906-010-0117-3  0.392
2010 Hackam DG, Khan NA, Hemmelgarn BR, Rabkin SW, Touyz RM, Campbell NR, Padwal R, Campbell TS, Lindsay MP, Hill MD, Quinn RR, Mahon JL, Herman RJ, Schiffrin EL, Ruzicka M, et al. The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. The Canadian Journal of Cardiology. 26: 249-58. PMID 20485689 DOI: 10.1016/S0828-282X(10)70379-2  0.354
2010 Schiffrin EL. Circulatory therapeutics: use of antihypertensive agents and their effects on the vasculature. Journal of Cellular and Molecular Medicine. 14: 1018-29. PMID 20345850 DOI: 10.1111/J.1582-4934.2010.01056.X  0.43
2010 Amiri F, Ko EA, Javeshghani D, Reudelhuber TL, Schiffrin EL. Deleterious combined effects of salt-loading and endothelial cell restricted endothelin-1 overexpression on blood pressure and vascular function in mice. Journal of Hypertension. 28: 1243-51. PMID 20308920 DOI: 10.1097/Hjh.0B013E328338Bb8B  0.421
2010 Briet M, Schiffrin EL. Aldosterone: effects on the kidney and cardiovascular system. Nature Reviews. Nephrology. 6: 261-73. PMID 20234356 DOI: 10.1038/Nrneph.2010.30  0.421
2010 Viel EC, Lemarié CA, Benkirane K, Paradis P, Schiffrin EL. Immune regulation and vascular inflammation in genetic hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 298: H938-44. PMID 20044442 DOI: 10.1152/Ajpheart.00707.2009  0.385
2010 Schiffrin EL. T lymphocytes: a role in hypertension? Current Opinion in Nephrology and Hypertension. 19: 181-6. PMID 20040866 DOI: 10.1097/Mnh.0B013E3283360A2E  0.393
2010 Savoia C, Ebrahimian T, Lemarié CA, Paradis P, Iglarz M, Amiri F, Javeshgani D, Schiffrin EL. Countervailing vascular effects of rosiglitazone in high cardiovascular risk mice: role of oxidative stress and PRMT-1. Clinical Science (London, England : 1979). 118: 583-92. PMID 19951259 DOI: 10.1042/Cs20090289  0.309
2010 Lemarié CA, Schiffrin EL. The angiotensin II type 2 receptor in cardiovascular disease. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 11: 19-31. PMID 19861349 DOI: 10.1177/1470320309347785  0.433
2009 Javeshghani D, Schiffrin EL, Sairam MR, Touyz RM. Potentiation of vascular oxidative stress and nitric oxide-mediated endothelial dysfunction by high-fat diet in a mouse model of estrogen deficiency and hyperandrogenemia. Journal of the American Society of Hypertension : Jash. 3: 295-305. PMID 20409973 DOI: 10.1016/J.Jash.2009.07.002  0.346
2009 Bouchentouf M, Paradis P, Forner KA, Cuerquis J, Boivin MN, Zheng J, Boulassel MR, Routy JP, Schiffrin EL, Galipeau J. Monocyte derivatives promote angiogenesis and myocyte survival in a model of myocardial infarction. Cell Transplantation. 19: 369-86. PMID 20021736 DOI: 10.3727/096368909X484266  0.325
2009 Marchesi C, Ebrahimian T, Angulo O, Paradis P, Schiffrin EL. Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndrome. Hypertension. 54: 1384-92. PMID 19822799 DOI: 10.1161/Hypertensionaha.109.138305  0.346
2009 Lemarié CA, Simeone SM, Nikonova A, Ebrahimian T, Deschênes ME, Coffman TM, Paradis P, Schiffrin EL. Aldosterone-induced activation of signaling pathways requires activity of angiotensin type 1a receptors. Circulation Research. 105: 852-9. PMID 19762686 DOI: 10.1161/Circresaha.109.196576  0.359
2009 Leibovitz E, Ebrahimian T, Paradis P, Schiffrin EL. Aldosterone induces arterial stiffness in absence of oxidative stress and endothelial dysfunction. Journal of Hypertension. 27: 2192-200. PMID 19654560 DOI: 10.1097/Hjh.0B013E328330A963  0.347
2009 Grassi G, Seravalle G, Scopelliti F, Dell'Oro R, Fattori L, Quarti-Trevano F, Brambilla G, Schiffrin EL, Mancia G. Structural and functional alterations of subcutaneous small resistance arteries in severe human obesity. Obesity (Silver Spring, Md.). 18: 92-8. PMID 19521345 DOI: 10.1038/Oby.2009.195  0.306
2009 Khan NA, Hemmelgarn B, Herman RJ, Bell CM, Mahon JL, Leiter LA, Rabkin SW, Hill MD, Padwal R, Touyz RM, Larochelle P, Feldman RD, Schiffrin EL, Campbell NR, Moe G, et al. The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2--therapy. The Canadian Journal of Cardiology. 25: 287-98. PMID 19417859 DOI: 10.1016/S0828-282X(09)70492-1  0.338
2009 Schiffrin EL, Paradis P. Suppression of peroxisome proliferator-activated receptor-gamma activity by angiotensin II in vascular smooth muscle involves Bcr kinase: the fire that drowns the water. Circulation Research. 104: 4-6. PMID 19118280 DOI: 10.1161/Circresaha.108.191155  0.452
2008 Marchesi C, Schiffrin EL. Peroxisome proliferator-activated receptors and the vascular system: beyond their metabolic effects. Journal of the American Society of Hypertension : Jash. 2: 227-38. PMID 20409905 DOI: 10.1016/J.Jash.2007.12.007  0.368
2008 Smith RD, Yokoyama H, Averill DB, Schiffrin EL, Ferrario CM. Reversal of vascular hypertrophy in hypertensive patients through blockade of angiotensin II receptors. Journal of the American Society of Hypertension : Jash. 2: 165-72. PMID 20409899 DOI: 10.1016/J.Jash.2007.11.001  0.483
2008 Levy BI, Schiffrin EL, Mourad JJ, Agostini D, Vicaut E, Safar ME, Struijker-Boudier HA. Impaired tissue perfusion: a pathology common to hypertension, obesity, and diabetes mellitus. Circulation. 118: 968-76. PMID 18725503 DOI: 10.1161/Circulationaha.107.763730  0.376
2008 Dhaun N, Goddard J, Kohan DE, Pollock DM, Schiffrin EL, Webb DJ. Role of endothelin-1 in clinical hypertension: 20 years on. Hypertension (Dallas, Tex. : 1979). 52: 452-9. PMID 18678788 DOI: 10.1161/Hypertensionaha.108.117366  0.366
2008 Ebrahimian T, Sairam MR, Schiffrin EL, Touyz RM. Cardiac hypertrophy is associated with altered thioredoxin and ASK-1 signaling in a mouse model of menopause. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1481-8. PMID 18676690 DOI: 10.1152/Ajpheart.00163.2008  0.414
2008 Marchesi C, Paradis P, Schiffrin EL. Role of the renin-angiotensin system in vascular inflammation. Trends in Pharmacological Sciences. 29: 367-74. PMID 18579222 DOI: 10.1016/J.Tips.2008.05.003  0.466
2008 Tabet F, Schiffrin EL, Callera GE, He Y, Yao G, Ostman A, Kappert K, Tonks NK, Touyz RM. Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR. Circulation Research. 103: 149-58. PMID 18566342 DOI: 10.1161/Circresaha.108.178608  0.411
2008 Khan NA, Hemmelgarn B, Herman RJ, Rabkin SW, McAlister FA, Bell CM, Touyz RM, Padwal R, Leiter LA, Mahon JL, Hill MD, Larochelle P, Feldman RD, Schiffrin EL, Campbell NR, et al. The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. The Canadian Journal of Cardiology. 24: 465-75. PMID 18548143 DOI: 10.1016/S0828-282X(08)70620-2  0.338
2008 Padwal RS, Hemmelgarn BR, Khan NA, Grover S, McAlister FA, McKay DW, Wilson T, Penner B, Burgess E, Bolli P, Hill MD, Mahon J, Myers MG, Abbott C, Schiffrin EL, et al. The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1 - blood pressure measurement, diagnosis and assessment of risk. The Canadian Journal of Cardiology. 24: 455-63. PMID 18548142 DOI: 10.1016/S0828-282X(08)70619-6  0.377
2008 Schiffrin EL. The Flame That Lights the Fire Oxidative Stress, Inflammation, and Renal Damage in Angiotensin II–Induced Hypertension Hypertension. 52: 205-206. PMID 18541731 DOI: 10.1161/Hypertensionaha.108.115402  0.466
2008 Viel EC, Benkirane K, Javeshghani D, Touyz RM, Schiffrin EL. Xanthine oxidase and mitochondria contribute to vascular superoxide anion generation in DOCA-salt hypertensive rats. American Journal of Physiology. Heart and Circulatory Physiology. 295: H281-8. PMID 18487445 DOI: 10.1152/Ajpheart.00304.2008  0.418
2008 Amiri F, Paradis P, Reudelhuber TL, Schiffrin EL. Vascular inflammation in absence of blood pressure elevation in transgenic murine model overexpressing endothelin-1 in endothelial cells. Journal of Hypertension. 26: 1102-9. PMID 18475147 DOI: 10.1097/Hjh.0B013E3282Fc2184  0.4
2008 Montezano AC, Callera GE, Yogi A, He Y, Tostes RC, He G, Schiffrin EL, Touyz RM. Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1511-8. PMID 18467645 DOI: 10.1161/Atvbaha.108.168021  0.418
2008 Lemarié CA, Paradis P, Schiffrin EL. New insights on signaling cascades induced by cross-talk between angiotensin II and aldosterone. Journal of Molecular Medicine (Berlin, Germany). 86: 673-8. PMID 18368382 DOI: 10.1007/S00109-008-0323-5  0.429
2008 Schiffrin EL. New twist to the role of the renin-angiotensin system in heart failure: aldosterone upregulates renin-angiotensin system components in the brain. Hypertension (Dallas, Tex. : 1979). 51: 622-3. PMID 18212262 DOI: 10.1161/Hypertensionaha.107.106898  0.403
2008 Savoia C, Schiffrin EL. Reduction of C-reactive protein and the use of anti-hypertensives. Vascular Health and Risk Management. 3: 975-83. PMID 18200816  0.328
2008 Savoia C, Touyz RM, Amiri F, Schiffrin EL. Selective mineralocorticoid receptor blocker eplerenone reduces resistance artery stiffness in hypertensive patients. Hypertension (Dallas, Tex. : 1979). 51: 432-9. PMID 18195160 DOI: 10.1161/Hypertensionaha.107.103267  0.44
2008 Pu Q, Brassard P, Javeshghani DM, Iglarz M, Webb RL, Amiri F, Schiffrin EL. Effects of combined AT1 receptor antagonist/NEP inhibitor on vascular remodeling and cardiac fibrosis in SHRSP. Journal of Hypertension. 26: 322-33. PMID 18192847 DOI: 10.1097/Hjh.0B013E3282F16Aaf  0.466
2008 Bakris G, Hill M, Mancia G, Steyn K, Black HR, Pickering T, De Geest S, Ruilope L, Giles TD, Morgan T, Kjeldsen S, Schiffrin EL, Coenen A, Mulrow P, Loh A, et al. Achieving blood pressure goals globally: five core actions for health-care professionals. A worldwide call to action. Journal of Human Hypertension. 22: 63-70. PMID 17728797 DOI: 10.1038/Sj.Jhh.1002284  0.312
2008 Smith RD, Yokoyama H, Averill DB, Schiffrin EL, Ferrario CM. Reversal of vascular hypertrophy in hypertensive patients through blockade of angiotensin II receptors Journal of the American Society of Hypertension. 2: 165-172. DOI: 10.1016/j.jash.2007.11.001  0.38
2007 Javeshghani D, Sairam MR, Schiffrin EL, Touyz RM. Increased blood pressure, vascular inflammation, and endothelial dysfunction in androgen-deficient follitropin receptor knockout male mice. Journal of the American Society of Hypertension : Jash. 1: 353-61. PMID 20409866 DOI: 10.1016/J.Jash.2007.06.003  0.428
2007 Schiffrin EL. Oxidative stress, nitric oxide synthase, and superoxide dismutase: a matter of imbalance underlies endothelial dysfunction in the human coronary circulation. Hypertension (Dallas, Tex. : 1979). 51: 31-2. PMID 18071058 DOI: 10.1161/Hypertensionaha.107.103226  0.405
2007 Sampaio WO, Henrique de Castro C, Santos RA, Schiffrin EL, Touyz RM. Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells. Hypertension (Dallas, Tex. : 1979). 50: 1093-8. PMID 17984366 DOI: 10.1161/Hypertensionaha.106.084848  0.415
2007 Leibovitz E, Schiffrin EL. PPAR activation: a new target for the treatment of hypertension. Journal of Cardiovascular Pharmacology. 50: 120-5. PMID 17703128 DOI: 10.1097/Fjc.0B013E318062153B  0.439
2007 Schiffrin EL, Lipman ML, Mann JF. Chronic kidney disease: effects on the cardiovascular system. Circulation. 116: 85-97. PMID 17606856 DOI: 10.1161/Circulationaha.106.678342  0.341
2007 Pandey NR, Benkirane K, Amiri F, Schiffrin EL. Effects of PPAR-gamma knock-down and hyperglycemia on insulin signaling in vascular smooth muscle cells from hypertensive rats. Journal of Cardiovascular Pharmacology. 49: 346-54. PMID 17577098 DOI: 10.1097/Fjc.0B013E31804654D7  0.32
2007 Ebrahimian T, He Y, Schiffrin EL, Touyz RM. Differential regulation of thioredoxin and NAD(P)H oxidase by angiotensin II in male and female mice. Journal of Hypertension. 25: 1263-71. PMID 17563540 DOI: 10.1097/Hjh.0B013E3280Acac60  0.327
2007 Khan NA, Hemmelgarn B, Padwal R, Larochelle P, Mahon JL, Lewanczuk RZ, McAlister FA, Rabkin SW, Hill MD, Feldman RD, Schiffrin EL, Campbell NR, Logan AG, Arnold M, Moe G, et al. The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. The Canadian Journal of Cardiology. 23: 539-50. PMID 17534460 DOI: 10.1016/S0828-282X(07)70798-5  0.337
2007 De Ciuceis C, Amiri F, Iglarz M, Cohn JS, Touyz RM, Schiffrin EL. Synergistic vascular protective effects of combined low doses of PPARalpha and PPARgamma activators in angiotensin II-induced hypertension in rats. British Journal of Pharmacology. 151: 45-53. PMID 17351653 DOI: 10.1038/Sj.Bjp.0707215  0.387
2007 Savoia C, Schiffrin EL. Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions. Clinical Science (London, England : 1979). 112: 375-84. PMID 17324119 DOI: 10.1042/Cs20060247  0.409
2007 Savoia C, Lemarie CA, Touyz RM, Rozen R, Volpe M, Schiffrin EL. Peroxisome Proliferator-Activated Receptors Activator, Rosiglitazone, Improves Vascular Structure and Reduces Lipid Deposition in Atherosclerotic Mthfr Knock-Out Mice High Blood Pressure & Cardiovascular Prevention. 14: 145-196. DOI: 10.2165/00151642-200714030-00180  0.321
2007 Savoia C, Schiffrin EL. Angiotensin Type 2 Receptors in the Cardiovascular System High Blood Pressure & Cardiovascular Prevention. 14: 63-68. DOI: 10.2165/00151642-200714020-00002  0.414
2006 Savoia C, Touyz RM, Volpe M, Schiffrin EL. Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients. Hypertension (Dallas, Tex. : 1979). 49: 341-6. PMID 17159079 DOI: 10.1161/01.Hyp.0000253968.95136.B8  0.451
2006 Ko EA, Amiri F, Pandey NR, Javeshghani D, Leibovitz E, Touyz RM, Schiffrin EL. Resistance artery remodeling in deoxycorticosterone acetate-salt hypertension is dependent on vascular inflammation: evidence from m-CSF-deficient mice. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1789-95. PMID 17142347 DOI: 10.1152/Ajpheart.01118.2006  0.375
2006 Sampaio WO, Souza dos Santos RA, Faria-Silva R, da Mata Machado LT, Schiffrin EL, Touyz RM. Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways. Hypertension (Dallas, Tex. : 1979). 49: 185-92. PMID 17116756 DOI: 10.1161/01.Hyp.0000251865.35728.2F  0.396
2006 Smith RD, Yokoyama H, Averill DB, Cooke L, Brosnihan KB, Schiffrin EL, Ferrario CM. The protective effects of angiotensin II blockade with olmesartan medoxomil on resistance vessel remodeling (The VIOS study): Rationale and baseline characteristics American Journal of Cardiovascular Drugs. 6: 335-342. PMID 17083268 DOI: 10.2165/00129784-200606050-00006  0.453
2006 Savoia C, Ebrahimian T, He Y, Gratton JP, Schiffrin EL, Touyz RM. Angiotensin II/AT2 receptor-induced vasodilation in stroke-prone spontaneously hypertensive rats involves nitric oxide and cGMP-dependent protein kinase. Journal of Hypertension. 24: 2417-22. PMID 17082724 DOI: 10.1097/01.Hjh.0000251902.85675.7E  0.438
2006 Savoia C, Schiffrin EL. Inhibition of the renin angiotensin system: implications for the endothelium. Current Diabetes Reports. 6: 274-8. PMID 16879778 DOI: 10.1007/S11892-006-0060-5  0.464
2006 Javeshghani D, Sairam MR, Neves MF, Schiffrin EL, Touyz RM. Angiotensin II induces vascular dysfunction without exacerbating blood pressure elevation in a mouse model of menopause-associated hypertension. Journal of Hypertension. 24: 1365-73. PMID 16794486 DOI: 10.1097/01.Hjh.0000234117.25401.F8  0.471
2006 Savoia C, Touyz RM, Endemann DH, Pu Q, Ko EA, De Ciuceis C, Schiffrin EL. Angiotensin receptor blocker added to previous antihypertensive agents on arteries of diabetic hypertensive patients. Hypertension (Dallas, Tex. : 1979). 48: 271-7. PMID 16785331 DOI: 10.1161/01.Hyp.0000230234.84356.36  0.418
2006 Touyz RM, Schiffrin EL. Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications. Vascular Pharmacology. 45: 19-28. PMID 16782410 DOI: 10.1016/J.Vph.2005.11.014  0.371
2006 Khan NA, McAlister FA, Rabkin SW, Padwal R, Feldman RD, Campbell NR, Leiter LA, Lewanczuk RZ, Schiffrin EL, Hill MD, Arnold M, Moe G, Campbell TS, Herbert C, Milot A, et al. The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part II - Therapy. The Canadian Journal of Cardiology. 22: 583-93. PMID 16755313 DOI: 10.1016/S0828-282X(06)70280-X  0.363
2006 Savoia C, Schiffrin EL. Inflammation in hypertension. Current Opinion in Nephrology and Hypertension. 15: 152-8. PMID 16481882 DOI: 10.1097/01.Mnh.0000203189.57513.76  0.375
2006 Schiffrin EL. Effects of aldosterone on the vasculature. Hypertension (Dallas, Tex. : 1979). 47: 312-8. PMID 16432039 DOI: 10.1161/01.Hyp.0000201443.63240.A7  0.426
2006 Neves MF, Amiri F, Virdis A, Diep QN, Schiffrin EL. Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy. Canadian Journal of Physiology and Pharmacology. 83: 999-1006. PMID 16391708 DOI: 10.1139/Y05-068  0.432
2006 Tabet F, Schiffrin EL, Touyz RM. Mitogen-activated protein kinase activation by hydrogen peroxide is mediated through tyrosine kinase-dependent, protein kinase C-independent pathways in vascular smooth muscle cells: upregulation in spontaneously hypertensive rats. Journal of Hypertension. 23: 2005-12. PMID 16208142 DOI: 10.1097/01.Hjh.0000185715.60788.1B  0.36
2006 Schiffrin EL. Blood pressure lowering in PROGRESS (Perindopril Protection Against Recurrent Stroke Study) and white matter hyperintensities: should this progress matter to patients? Circulation. 112: 1525-6. PMID 16157782 DOI: 10.1161/Circulationaha.105.566489  0.317
2006 Benkirane K, Amiri F, Diep QN, El Mabrouk M, Schiffrin EL. PPAR-gamma inhibits ANG II-induced cell growth via SHIP2 and 4E-BP1. American Journal of Physiology. Heart and Circulatory Physiology. 290: H390-7. PMID 16155101 DOI: 10.1152/Ajpheart.00662.2005  0.808
2006 Cruzado MC, Risler NR, Miatello RM, Yao G, Schiffrin EL, Touyz RM. Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: Effect of angiotensin II and role of insulinlike growth factor-1 receptor transactivation. American Journal of Hypertension. 18: 81-7. PMID 15691621 DOI: 10.1016/J.Amjhyper.2004.09.001  0.485
2006 Schiffrin EL. Remodeling of resistance arteries in essential hypertension and effects of antihypertensive treatment. American Journal of Hypertension. 17: 1192-200. PMID 15607629 DOI: 10.1016/J.Amjhyper.2004.05.023  0.452
2006 Schiffrin EL. Vascular stiffening and arterial compliance. Implications for systolic blood pressure. American Journal of Hypertension. 17: 39S-48S. PMID 15607434 DOI: 10.1016/J.Amjhyper.2004.08.019  0.438
2006 Savoia C, Touyz RM, Schiffrin EL. Response to Are the Eutrophic Effects of Angiotensin Receptor Blockers Real? Hypertension. 48. DOI: 10.1161/01.Hyp.0000238606.74107.26  0.438
2005 Benkirane K, Viel EC, Amiri F, Schiffrin EL. Peroxisome proliferator-activated receptor gamma regulates angiotensin II-stimulated phosphatidylinositol 3-kinase and mitogen-activated protein kinase in blood vessels in vivo. Hypertension (Dallas, Tex. : 1979). 47: 102-8. PMID 16344371 DOI: 10.1161/01.Hyp.0000196728.05488.C3  0.485
2005 Brassard P, Amiri F, Thibault G, Schiffrin EL. Role of angiotensin type-1 and angiotensin type-2 receptors in the expression of vascular integrins in angiotensin II-infused rats. Hypertension (Dallas, Tex. : 1979). 47: 122-7. PMID 16330679 DOI: 10.1161/01.Hyp.0000196272.79321.11  0.449
2005 Callera GE, Montezano AC, Yogi A, Tostes RC, He Y, Schiffrin EL, Touyz RM. c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 46: 1032-8. PMID 16157790 DOI: 10.1161/01.Hyp.0000176588.51027.35  0.45
2005 De Ciuceis C, Amiri F, Brassard P, Endemann DH, Touyz RM, Schiffrin EL. Reduced vascular remodeling, endothelial dysfunction, and oxidative stress in resistance arteries of angiotensin II-infused macrophage colony-stimulating factor-deficient mice: evidence for a role in inflammation in angiotensin-induced vascular injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2106-13. PMID 16100037 DOI: 10.1161/01.Atv.0000181743.28028.57  0.41
2005 Yokoyama H, Averill DB, Brosnihan KB, Smith RD, Schiffrin EL, Ferrario CM. Role of blood pressure reduction in prevention of cardiac and vascular hypertrophy American Journal of Hypertension. 18: 922-929. PMID 16053988 DOI: 10.1016/J.Amjhyper.2005.01.009  0.483
2005 Brassard P, Amiri F, Schiffrin EL. Combined angiotensin II type 1 and type 2 receptor blockade on vascular remodeling and matrix metalloproteinases in resistance arteries. Hypertension (Dallas, Tex. : 1979). 46: 598-606. PMID 16043661 DOI: 10.1161/01.Hyp.0000176744.15592.7D  0.438
2005 Schiffrin EL. More evidence of cardiorenal protective effects of peroxisome proliferator-activated receptor activation. Hypertension (Dallas, Tex. : 1979). 46: 267-8. PMID 15967865 DOI: 10.1161/01.Hyp.0000172756.41375.E4  0.322
2005 Schiffrin EL. Vascular endothelin in hypertension. Vascular Pharmacology. 43: 19-29. PMID 15955745 DOI: 10.1016/J.Vph.2005.03.004  0.515
2005 Savoia C, Tabet F, Yao G, Schiffrin EL, Touyz RM. Negative regulation of RhoA/Rho kinase by angiotensin II type 2 receptor in vascular smooth muscle cells: role in angiotensin II-induced vasodilation in stroke-prone spontaneously hypertensive rats. Journal of Hypertension. 23: 1037-45. PMID 15834290 DOI: 10.1097/01.Hjh.0000166845.49850.39  0.442
2005 Touyz RM, Yao G, Schiffrin EL. Role of the actin cytoskeleton in angiotensin II signaling in human vascular smooth muscle cells. Canadian Journal of Physiology and Pharmacology. 83: 91-7. PMID 15759055 DOI: 10.1139/Y05-006  0.386
2005 Schiffrin EL, Touyz RM. Calcium, magnesium, and oxidative stress in hyperaldosteronism. Circulation. 111: 830-1. PMID 15723988 DOI: 10.1161/01.Cir.0000157186.95918.78  0.354
2005 Callera GE, Touyz RM, Tostes RC, Yogi A, He Y, Malkinson S, Schiffrin EL. Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src. Hypertension (Dallas, Tex. : 1979). 45: 773-9. PMID 15699470 DOI: 10.1161/01.Hyp.0000154365.30593.D3  0.325
2005 Pu Q, Amiri F, Gannon P, Schiffrin EL. Dual angiotensin-converting enzyme/neutral endopeptidase inhibition on cardiac and renal fibrosis and inflammation in DOCA-salt hypertensive rats. Journal of Hypertension. 23: 401-9. PMID 15662229 DOI: 10.1097/00004872-200502000-00023  0.398
2005 Diep QN, Amiri F, Benkirane K, Paradis P, Schiffrin EL. Long-term effects of the PPAR gamma activator pioglitazone on cardiac inflammation in stroke-prone spontaneously hypertensive rats. Canadian Journal of Physiology and Pharmacology. 82: 976-85. PMID 15644937 DOI: 10.1139/Y04-094  0.401
2005 Deanfield J, Donald A, Ferri C, Giannattasio C, Halcox J, Halligan S, Lerman A, Mancia G, Oliver JJ, Pessina AC, Rizzoni D, Rossi GP, Salvetti A, Schiffrin EL, Taddei S, et al. Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension. Journal of Hypertension. 23: 7-17. PMID 15643116 DOI: 10.1097/00004872-200501000-00004  0.338
2005 Touyz RM, Yao G, Viel E, Amiri F, Schiffrin EL. Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells. Journal of Hypertension. 22: 1141-9. PMID 15167449 DOI: 10.1097/00004872-200406000-00015  0.383
2005 DECIUCEIS C, AMIRI F, ENDEMANN D, TOUYZ R, SCHIFFRIN E. Resistance arteries of Ang II-infused osteopetrotic mice show reduced impairment of endothelial function, oxidative stress, and vascular remodeling: Role of inflammation and mCSF in hypertension American Journal of Hypertension. 18: A242-A242. DOI: 10.1016/J.Amjhyper.2005.03.660  0.437
2005 TOUYZ R, YAO G, SCHIFFRIN E. Role of the actin cytoskeleton in angiotensin II signaling in human vascular smooth muscle cells American Journal of Hypertension. 18: A237-A237. DOI: 10.1016/J.Amjhyper.2005.03.650  0.363
2005 YOKOYAMA H, SMITH R, AVERILL D, SCHIFFRIN E, FERRARIO C. Vascular improvement with olmesartan medoxomil American Journal of Hypertension. 18: A23-A23. DOI: 10.1016/J.Amjhyper.2005.03.060  0.335
2004 Amiri F, Virdis A, Neves MF, Iglarz M, Seidah NG, Touyz RM, Reudelhuber TL, Schiffrin EL. Endothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction. Circulation. 110: 2233-40. PMID 15466627 DOI: 10.1161/01.Cir.0000144462.08345.B9  0.392
2004 Schiffrin EL. Peroxisome proliferator-activated receptors and cardiovascular remodeling. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1037-43. PMID 15374828 DOI: 10.1152/Ajpheart.00677.2004  0.39
2004 Touyz RM, Schiffrin EL. Reactive oxygen species in vascular biology: implications in hypertension. Histochemistry and Cell Biology. 122: 339-52. PMID 15338229 DOI: 10.1007/S00418-004-0696-7  0.376
2004 Schiffrin EL, Touyz RM. From bedside to bench to bedside: role of renin-angiotensin-aldosterone system in remodeling of resistance arteries in hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 287: H435-46. PMID 15277186 DOI: 10.1152/Ajpheart.00262.2004  0.373
2004 Endemann DH, Touyz RM, Iglarz M, Savoia C, Schiffrin EL. Eplerenone prevents salt-induced vascular remodeling and cardiac fibrosis in stroke-prone spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 43: 1252-7. PMID 15117913 DOI: 10.1161/01.Hyp.0000128031.31572.A3  0.453
2004 Neves MF, Endemann D, Amiri F, Virdis A, Pu Q, Rozen R, Schiffrin EL. Small artery mechanics in hyperhomocysteinemic mice: effects of angiotensin II. Journal of Hypertension. 22: 959-66. PMID 15097236 DOI: 10.1097/00004872-200405000-00018  0.393
2004 Elijovich F, Laffer CL, Schiffrin EL, Gavras H, Amador E. Endothelin-aldosterone interaction and proteinuria in low-renin hypertension. Journal of Hypertension. 22: 573-82. PMID 15076164 DOI: 10.1097/00004872-200403000-00021  0.422
2004 Virdis A, Neves MF, Amiri F, Touyz RM, Schiffrin EL. Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice. Journal of Hypertension. 22: 535-42. PMID 15076159 DOI: 10.1097/00004872-200403000-00016  0.397
2004 Endemann DH, Schiffrin EL. Nitric oxide, oxidative excess, and vascular complications of diabetes mellitus. Current Hypertension Reports. 6: 85-9. PMID 15010009 DOI: 10.1007/S11906-004-0081-X  0.319
2004 Schiffrin EL. The many targets of aldosterone. Hypertension (Dallas, Tex. : 1979). 43: 938-40. PMID 15007036 DOI: 10.1161/01.Hyp.0000123573.60340.9B  0.348
2004 Callera GE, Montezano AC, Touyz RM, Zorn TM, Carvalho MH, Fortes ZB, Nigro D, Schiffrin EL, Tostes RC. ETA receptor mediates altered leukocyte-endothelial cell interaction and adhesion molecules expression in DOCA-salt rats. Hypertension (Dallas, Tex. : 1979). 43: 872-9. PMID 14993193 DOI: 10.1161/01.Hyp.0000117296.30296.14  0.413
2004 Diep QN, Benkirane K, Amiri F, Cohn JS, Endemann D, Schiffrin EL. PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats. Journal of Molecular and Cellular Cardiology. 36: 295-304. PMID 14871557 DOI: 10.1016/J.Yjmcc.2003.11.004  0.348
2004 Savoia C, Schiffrin EL. Significance of recently identified peptides in hypertension: endothelin, natriuretic peptides, adrenomedullin, leptin. The Medical Clinics of North America. 88: 39-62. PMID 14871050 DOI: 10.1016/S0025-7125(03)00122-6  0.36
2004 Endemann DH, Pu Q, De Ciuceis C, Savoia C, Virdis A, Neves MF, Touyz RM, Schiffrin EL. Persistent remodeling of resistance arteries in type 2 diabetic patients on antihypertensive treatment. Hypertension (Dallas, Tex. : 1979). 43: 399-404. PMID 14707158 DOI: 10.1161/01.Hyp.0000112029.03691.E7  0.403
2004 El Mabrouk M, Diep QN, Benkirane K, Touyz RM, Schiffrin EL. SAM68: a downstream target of angiotensin II signaling in vascular smooth muscle cells in genetic hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1954-62. PMID 14693677 DOI: 10.1152/Ajpheart.00134.2003  0.802
2004 Touyz RM, Tabet F, Schiffrin EL. Redox-dependent signalling by angiotensin II and vascular remodelling in hypertension. Clinical and Experimental Pharmacology & Physiology. 30: 860-6. PMID 14678251 DOI: 10.1046/J.1440-1681.2003.03930.X  0.477
2004 Schiffrin EL. The angiotensin-endothelin relationship: does it play a role in cardiovascular and renal pathophysiology? Journal of Hypertension. 21: 2245-7. PMID 14654742 DOI: 10.1097/01.Hjh.0000098171.36890.E2  0.333
2004 Pu Q, Larouche I, Schiffrin EL. Effect of dual angiotensin converting enzyme/neutral endopeptidase inhibition, angiotensin converting enzyme inhibition, or AT1 antagonism on coronary microvasculature in spontaneously hypertensive rats. American Journal of Hypertension. 16: 931-7. PMID 14573331 DOI: 10.1016/S0895-7061(03)01029-X  0.422
2004 Touyz RM, Schiffrin EL. Role of endothelin in human hypertension. Canadian Journal of Physiology and Pharmacology. 81: 533-41. PMID 12839265 DOI: 10.1139/Y03-009  0.466
2004 Moreau P, Schiffrin EL. Role of endothelins in animal models of hypertension: focus on cardiovascular protection. Canadian Journal of Physiology and Pharmacology. 81: 511-21. PMID 12839263 DOI: 10.1139/Y03-015  0.459
2004 Schiffrin EL, Touyz RM. Inflammation and vascular hypertrophy induced by angiotensin II: role of NADPH oxidase-derived reactive oxygen species independently of blood pressure elevation? Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 707-9. PMID 12740221 DOI: 10.1161/01.Atv.0000069907.12357.7E  0.476
2004 Virdis A, Schiffrin EL. Vascular inflammation: a role in vascular disease in hypertension? Current Opinion in Nephrology and Hypertension. 12: 181-7. PMID 12589179 DOI: 10.1097/00041552-200303000-00009  0.383
2004 Ammarguellat F, Larouche I, Schiffrin EL. Myocardial fibrosis in DOCA-salt hypertensive rats: effect of endothelin ET(A) receptor antagonism. Circulation. 103: 319-24. PMID 11208696 DOI: 10.1161/01.Cir.103.2.319  0.409
2004 Elijovich F, Laffer CL, Amador E, Gavras H, Bresnahan MR, Schiffrin EL. Regulation of plasma endothelin by salt in salt-sensitive hypertension. Circulation. 103: 263-8. PMID 11208687 DOI: 10.1161/01.Cir.103.2.263  0.414
2004 Neves MF, Amiri F, Virdis A, Diep QN, Schiffrin EL. EFFECTS OF SPIRONOLACTONE ON CARDIAC INFLAMMATION AND FIBROSIS IN ANGIOTENSIN II-INDUCED HYPERTENSION Journal of Hypertension. 22: S163. DOI: 10.1097/00004872-200402001-00693  0.313
2004 Benkirane K, Amiri F, Schiffrin EL. PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA INTERFERES WITH ANGIOTENSIN II SIGNALING IN BLOOD VESSELS Journal of Hypertension. 22: S76. DOI: 10.1097/00004872-200402001-00319  0.307
2004 IGLARZ M, TOUYZ R, VIEL E, AMIRI F, SCHIFFRIN E. American Journal of Hypertension. 17: 597-603. DOI: 10.1016/J.Amjhyper.2004.04.005  0.422
2003 Schiffrin EL, Touyz RM. Multiple actions of angiotensin II in hypertension: benefits of AT1 receptor blockade. Journal of the American College of Cardiology. 42: 911-3. PMID 12957442 DOI: 10.1016/S0735-1097(03)00845-3  0.445
2003 Callera GE, Touyz RM, Teixeira SA, Muscara MN, Carvalho MH, Fortes ZB, Nigro D, Schiffrin EL, Tostes RC. ETA receptor blockade decreases vascular superoxide generation in DOCA-salt hypertension. Hypertension (Dallas, Tex. : 1979). 42: 811-7. PMID 12913063 DOI: 10.1161/01.Hyp.0000088363.65943.6C  0.361
2003 Javeshghani D, Touyz RM, Sairam MR, Virdis A, Neves MF, Schiffrin EL. Attenuated responses to angiotensin II in follitropin receptor knockout mice, a model of menopause-associated hypertension. Hypertension. 42: 761-7. PMID 12885794 DOI: 10.1161/01.Hyp.0000085331.22169.3F  0.439
2003 Schiffrin EL, Amiri F, Benkirane K, Iglarz M, Diep QN. Peroxisome proliferator-activated receptors: vascular and cardiac effects in hypertension. Hypertension (Dallas, Tex. : 1979). 42: 664-8. PMID 12874098 DOI: 10.1161/01.Hyp.0000084370.74777.B6  0.417
2003 Iglarz M, Touyz RM, Viel EC, Paradis P, Amiri F, Diep QN, Schiffrin EL. Peroxisome proliferator-activated receptor-alpha and receptor-gamma activators prevent cardiac fibrosis in mineralocorticoid-dependent hypertension. Hypertension (Dallas, Tex. : 1979). 42: 737-43. PMID 12860836 DOI: 10.1161/01.Hyp.0000083511.91817.B1  0.427
2003 Ruilope LM, Segura J, Schiffrin EL. ACE inhibition or angiotensin receptor blockade: which should we use in diabetic patients? Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 4: 74-9. PMID 12806588 DOI: 10.3317/Jraas.2003.016  0.378
2003 Pu Q, Neves MF, Virdis A, Touyz RM, Schiffrin EL. Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling. Hypertension (Dallas, Tex. : 1979). 42: 49-55. PMID 12782645 DOI: 10.1161/01.Hyp.0000078357.92682.Ec  0.473
2003 Schiffrin EL. Effect of antihypertensive treatment on small artery remodeling in hypertension. Canadian Journal of Physiology and Pharmacology. 81: 168-76. PMID 12710531 DOI: 10.1139/Y02-158  0.479
2003 Touyz RM, Cruzado M, Tabet F, Yao G, Salomon S, Schiffrin EL. Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation. Canadian Journal of Physiology and Pharmacology. 81: 159-67. PMID 12710530 DOI: 10.1139/Y02-164  0.371
2003 Touyz RM, Yao G, Schiffrin EL. c-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 981-7. PMID 12663375 DOI: 10.1161/01.Atv.0000069236.27911.68  0.393
2003 Iglarz M, Schiffrin EL. Role of endothelin-1 in hypertension. Current Hypertension Reports. 5: 144-8. PMID 12642014 DOI: 10.1007/S11906-003-0071-4  0.488
2003 Douglas JG, Bakris GL, Epstein M, Ferdinand KC, Ferrario C, Flack JM, Jamerson KA, Jones WE, Haywood J, Maxey R, Ofili EO, Saunders E, Schiffrin EL, Sica DA, Sowers JR, et al. Management of high blood pressure in African Americans: consensus statement of the Hypertension in African Americans Working Group of the International Society on Hypertension in Blacks. Archives of Internal Medicine. 163: 525-41. PMID 12622600 DOI: 10.1001/Archinte.163.5.525  0.368
2003 Neves MF, Virdis A, Schiffrin EL. Resistance artery mechanics and composition in angiotensin II-infused rats: effects of aldosterone antagonism. Journal of Hypertension. 21: 189-98. PMID 12544451 DOI: 10.1097/00004872-200301000-00029  0.415
2003 Fritsch Neves M, Schiffrin EL. Aldosterone: a risk factor for vascular disease. Current Hypertension Reports. 5: 59-65. PMID 12530937 DOI: 10.1007/S11906-003-0012-2  0.479
2003 Iglarz M, Touyz RM, Amiri F, Lavoie MF, Diep QN, Schiffrin EL. Effect of peroxisome proliferator-activated receptor-alpha and -gamma activators on vascular remodeling in endothelin-dependent hypertension. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 45-51. PMID 12524223 DOI: 10.1161/01.Atv.0000047447.67827.Cd  0.406
2003 Diep QN, Amiri F, Touyz RM, Cohn JS, Endemann D, Neves MF, Schiffrin EL. PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation. Hypertension (Dallas, Tex. : 1979). 40: 866-71. PMID 12468571 DOI: 10.1161/01.Hyp.0000037969.41360.Cc  0.51
2003 Schiffrin EL. Beyond blood pressure: the endothelium and atherosclerosis progression. American Journal of Hypertension. 15: 115S-122S. PMID 12383592 DOI: 10.1016/S0895-7061(02)03006-6  0.499
2002 Schiffrin EL. Vascular and cardiac benefits of angiotensin receptor blockers. The American Journal of Medicine. 113: 409-18. PMID 12401536 DOI: 10.1016/S0002-9343(02)01241-X  0.457
2002 Virdis A, Neves MF, Amiri F, Viel E, Touyz RM, Schiffrin EL. Spironolactone improves angiotensin-induced vascular changes and oxidative stress. Hypertension (Dallas, Tex. : 1979). 40: 504-10. PMID 12364354 DOI: 10.1161/01.Hyp.0000034738.79310.06  0.471
2002 Tostes RC, Touyz RM, He G, Chen X, Schiffrin EL. Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension. Clinical Science (London, England : 1979). 25S-30S. PMID 12193048 DOI: 10.1042/Cs103S025S  0.39
2002 Endemann D, Touyz RM, Yao G, Schiffrin EL. Tyrosine kinase inhibition attenuates vasopressin-induced contraction of mesenteric resistance arteries: alterations in spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology. 40: 123-32. PMID 12072585 DOI: 10.1097/00005344-200207000-00015  0.429
2002 Touyz RM, Chen X, Tabet F, Yao G, He G, Quinn MT, Pagano PJ, Schiffrin EL. Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: Regulation by angiotensin II Circulation Research. 90: 1205-1213. PMID 12065324 DOI: 10.1161/01.Res.0000020404.01971.2F  0.408
2002 Schiffrin EL. Vascular changes in hypertension in response to drug treatment: Effects of angiotensin receptor blockers. The Canadian Journal of Cardiology. 15A-18A. PMID 12045789  0.394
2002 Touyz RM, Deschepper C, Park JB, He G, Chen X, Neves MF, Virdis A, Schiffrin EL. Inhibition of mitogen-activated protein/extracellular signal-regulated kinase improves endothelial function and attenuates Ang II-induced contractility of mesenteric resistance arteries from spontaneously hypertensive rats. Journal of Hypertension. 20: 1127-34. PMID 12023682 DOI: 10.1097/00004872-200206000-00024  0.478
2002 Tostes RC, Touyz RM, He G, Ammarguellat F, Schiffrin EL. Endothelin A receptor blockade decreases expression of growth factors and collagen and improves matrix metalloproteinase-2 activity in kidneys from stroke-prone spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology. 39: 892-900. PMID 12021584 DOI: 10.1097/00005344-200206000-00015  0.356
2002 Pu Q, Touyz RM, Schiffrin EL. Comparison of angiotensin-converting enzyme (ACE), neutral endopeptidase (NEP) and dual ACE/NEP inhibition on blood pressure and resistance arteries of deoxycorticosterone acetate-salt hypertensive rats. Journal of Hypertension. 20: 899-907. PMID 12011651 DOI: 10.1097/00004872-200205000-00025  0.427
2002 Diep QN, El Mabrouk M, Cohn JS, Endemann D, Amiri F, Virdis A, Neves MF, Schiffrin EL. Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-gamma. Circulation. 105: 2296-302. PMID 12010913 DOI: 10.1161/01.Cir.0000016049.86468.23  0.829
2002 Park JB, Intengan HD, Schiffrin EL. Reduction of resistance artery stiffness by treatment with the AT(1)-receptor antagonist losartan in essential hypertension. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 1: 40-5. PMID 11967798 DOI: 10.3317/Jraas.2000.009  0.446
2002 Diep QN, El Mabrouk M, Yue P, Schiffrin EL. Effect of AT(1) receptor blockade on cardiac apoptosis in angiotensin II-induced hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 282: H1635-41. PMID 11959625 DOI: 10.1152/Ajpheart.00984.2001  0.8
2002 Ammarguellat FZ, Gannon PO, Amiri F, Schiffrin EL. Fibrosis, matrix metalloproteinases, and inflammation in the heart of DOCA-salt hypertensive rats: role of ET(A) receptors. Hypertension (Dallas, Tex. : 1979). 39: 679-84. PMID 11882630 DOI: 10.1161/Hy0202.103481  0.377
2002 Touyz RM, Wu XH, He G, Salomon S, Schiffrin EL. Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 39: 479-85. PMID 11882594 DOI: 10.1161/Hy02T2.102909  0.435
2002 Park JB, Schiffrin EL. Cardiac and vascular fibrosis and hypertrophy in aldosterone-infused rats: role of endothelin-1. American Journal of Hypertension. 15: 164-9. PMID 11863252 DOI: 10.1016/S0895-7061(01)02291-9  0.391
2002 Schiffrin EL, Pu Q, Park JB. Effect of amlodipine compared to atenolol on small arteries of previously untreated essential hypertensive patients. American Journal of Hypertension. 15: 105-10. PMID 11863244 DOI: 10.1016/S0895-7061(01)02290-7  0.41
2002 Park JB, Touyz RM, Chen X, Schiffrin EL. Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive rats. American Journal of Hypertension. 15: 78-84. PMID 11824865 DOI: 10.1016/S0895-7061(01)02233-6  0.472
2002 Schiffrin EL. A critical review of the role of endothelial factors in the pathogenesis of hypertension. Journal of Cardiovascular Pharmacology. S3-6. PMID 11811373 DOI: 10.1097/00005344-200111002-00002  0.467
2002 Schiffrin EL, Park JB, Pu Q. Effect of crossing over hypertensive patients from a beta-blocker to an angiotensin receptor antagonist on resistance artery structure and on endothelial function. Journal of Hypertension. 20: 71-8. PMID 11791028 DOI: 10.1097/00004872-200201000-00011  0.416
2002 Pu Q, Schiffrin EL. Effect of ACE/NEP inhibition on cardiac and vascular collagen in stroke-prone spontaneously hypertensive rats. American Journal of Hypertension. 14: 1067-72. PMID 11710787 DOI: 10.1016/S0895-7061(01)02157-4  0.426
2001 Touyz RM, Schiffrin EL. Measurement of phospholipase d activation in vascular smooth muscle cells. Methods in Molecular Medicine. 51: 355-362. PMID 21331729 DOI: 10.1385/1-59259-087-X:355  0.364
2001 Chen X, Touyz RM, Park JB, Schiffrin EL. Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR. Hypertension (Dallas, Tex. : 1979). 38: 606-11. PMID 11566940 DOI: 10.1161/Hy09T1.094005  0.369
2001 Intengan HD, Schiffrin EL. Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis. Hypertension (Dallas, Tex. : 1979). 38: 581-7. PMID 11566935 DOI: 10.1161/Hy09T1.096249  0.434
2001 Ruilope LM, Schiffrin EL. Blood pressure control and benefits of antihypertensive therapy: does it make a difference which agents we use? Hypertension (Dallas, Tex. : 1979). 38: 537-42. PMID 11566927 DOI: 10.1161/Hy09T1.095760  0.421
2001 Diep QN, Schiffrin EL. Increased expression of peroxisome proliferator-activated receptor-alpha and -gamma in blood vessels of spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 38: 249-54. PMID 11509485 DOI: 10.1161/01.Hyp.38.2.249  0.378
2001 Schiffrin EL. Effects of antihypertensive drugs on vascular remodeling: do they predict outcome in response to antihypertensive therapy? Current Opinion in Nephrology and Hypertension. 10: 617-24. PMID 11496055 DOI: 10.1097/00041552-200109000-00011  0.454
2001 Schiffrin EL. Small artery remodeling in hypertension: can it be corrected? The American Journal of the Medical Sciences. 322: 7-11. PMID 11465250 DOI: 10.1097/00000441-200107000-00002  0.484
2001 Touyz RM, He G, Wu XH, Park JB, Mabrouk ME, Schiffrin EL. Src is an important mediator of extracellular signal-regulated kinase 1/2-dependent growth signaling by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients. Hypertension (Dallas, Tex. : 1979). 38: 56-64. PMID 11463760 DOI: 10.1161/01.Hyp.38.1.56  0.379
2001 Touyz RM, Schiffrin EL. Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways. Journal of Hypertension. 19: 1245-54. PMID 11446714 DOI: 10.1097/00004872-200107000-00009  0.443
2001 Schiffrin EL. Role of endothelin-1 in hypertension and vascular disease. American Journal of Hypertension. 14: 83S-89S. PMID 11411770 DOI: 10.1016/S0895-7061(01)02074-X  0.491
2001 Park JB, Schiffrin EL. ET(A) receptor antagonist prevents blood pressure elevation and vascular remodeling in aldosterone-infused rats. Hypertension (Dallas, Tex. : 1979). 37: 1444-9. PMID 11408393 DOI: 10.1161/01.Hyp.37.6.1444  0.503
2001 El Mabrouk M, Touyz RM, Schiffrin EL. Differential ANG II-induced growth activation pathways in mesenteric artery smooth muscle cells from SHR. American Journal of Physiology. Heart and Circulatory Physiology. 281: H30-9. PMID 11406465 DOI: 10.1152/Ajpheart.2001.281.1.H30  0.437
2001 Park JB, Schiffrin EL. Small artery remodeling is the most prevalent (earliest?) form of target organ damage in mild essential hypertension. Journal of Hypertension. 19: 921-30. PMID 11393676 DOI: 10.1097/00004872-200105000-00013  0.435
2001 Chen J, Fabry B, Schiffrin EL, Wang N. Twisting integrin receptors increases endothelin-1 gene expression in endothelial cells. American Journal of Physiology. Cell Physiology. 280: C1475-84. PMID 11350743 DOI: 10.1152/Ajpcell.2001.280.6.C1475  0.304
2001 Touyz RM, He G, El Mabrouk M, Diep Q, Mardigyan V, Schiffrin EL. Differential activation of extracellular signal-regulated protein kinase 1/2 and p38 mitogen activated-protein kinase by AT1 receptors in vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats. Journal of Hypertension. 19: 553-9. PMID 11327629 DOI: 10.1097/00004872-200103001-00006  0.392
2001 Touyz RM, Wu XH, He G, Park JB, Chen X, Vacher J, Rajapurohitam V, Schiffrin EL. Role of c-Src in the regulation of vascular contraction and Ca2+ signaling by angiotensin II in human vascular smooth muscle cells. Journal of Hypertension. 19: 441-9. PMID 11288814 DOI: 10.1097/00004872-200103000-00012  0.394
2001 Park JB, Charbonneau F, Schiffrin EL. Correlation of endothelial function in large and small arteries in human essential hypertension. Journal of Hypertension. 19: 415-20. PMID 11288811 DOI: 10.1097/00004872-200103000-00009  0.411
2001 Diep QN, El Mabrouk M, Touyz RM, Schiffrin EL. Expression of cell cycle proteins in blood vessels of angiotensin II-infused rats: role of AT(1) receptors. Hypertension. 37: 604-8. PMID 11230342 DOI: 10.1161/01.Hyp.37.2.604  0.446
2001 Touyz RM, He G, El Mabrouk M, Schiffrin EL. p38 Map kinase regulates vascular smooth muscle cell collagen synthesis by angiotensin II in SHR but not in WKY. Hypertension. 37: 574-80. PMID 11230337 DOI: 10.1161/01.Hyp.37.2.574  0.396
2001 Touyz RM, Turgeon A, Schiffrin EL. Endothelin-A-receptor blockade improves renal function and doubles the lifespan of stroke-prone spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology. 36: S300-4. PMID 11078404 DOI: 10.1097/00005344-200036051-00088  0.36
2000 Diep QN, Touyz RM, Schiffrin EL. Docosahexaenoic acid, a peroxisome proliferator-activated receptor-alpha ligand, induces apoptosis in vascular smooth muscle cells by stimulation of p38 mitogen-activated protein kinase. Hypertension (Dallas, Tex. : 1979). 36: 851-5. PMID 11082155 DOI: 10.1161/01.Hyp.36.5.851  0.346
2000 Intengan HD, Schiffrin EL. Structure and mechanical properties of resistance arteries in hypertension: role of adhesion molecules and extracellular matrix determinants. Hypertension (Dallas, Tex. : 1979). 36: 312-8. PMID 10988257 DOI: 10.1161/01.Hyp.36.3.312  0.396
2000 El Mabrouk M, Singh A, Touyz RM, Schiffrin EL. Antiproliferative effect of L-NAME on rat vascular smooth muscle cells. Life Sciences. 67: 1613-23. PMID 10983855 DOI: 10.1016/S0024-3205(00)00744-X  0.32
2000 Park JB, Schiffrin EL. Effects of antihypertensive therapy on hypertensive vascular disease. Current Hypertension Reports. 2: 280-8. PMID 10981161 DOI: 10.1007/S11906-000-0011-5  0.48
2000 Schiffrin EL. Endothelin: role in experimental hypertension. Journal of Cardiovascular Pharmacology. 35: S33-35. PMID 10976778 DOI: 10.1097/00005344-200000002-00008  0.48
2000 Intengan HD, Schiffrin EL. Vasopeptidase inhibition has potent effects on blood pressure and resistance arteries in stroke-prone spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 35: 1221-5. PMID 10856267 DOI: 10.1161/01.Hyp.35.6.1221  0.469
2000 Intengan HD, Schiffrin EL. Disparate effects of carvedilol versus metoprolol treatment of stroke-prone spontaneously hypertensive rats on endothelial function of resistance arteries. Journal of Cardiovascular Pharmacology. 35: 763-8. PMID 10813379 DOI: 10.1097/00005344-200005000-00013  0.449
2000 Schiffrin EL, Park JB, Intengan HD, Touyz RM. Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation. 101: 1653-9. PMID 10758046 DOI: 10.1161/01.Cir.101.14.1653  0.481
2000 Fareh J, Touyz RM, Schiffrin EL, Thibault G. Altered cardiac endothelin receptors and protein kinase C in deoxycorticosterone-salt hypertensive rats. Journal of Molecular and Cellular Cardiology. 32: 665-76. PMID 10756122 DOI: 10.1006/Jmcc.2000.1110  0.381
2000 Diep QN, Intengan HD, Schiffrin EL. Endothelin-1 attenuates omega3 fatty acid-induced apoptosis by inhibition of caspase 3. Hypertension (Dallas, Tex. : 1979). 35: 287-91. PMID 10642312 DOI: 10.1161/01.Hyp.35.1.287  0.309
2000 Park JB, Schiffrin EL. Eta Receptor Antagonist Prevents Blood Pressure Elevation and Vascular Hypertrophy of Resistance Arteries in Aldosterone-Infused Rats. Hypertension. 36: 724-724. DOI: 10.1161/01.Hyp.36.Suppl_1.724-C  0.491
2000 Touyz RM, He G, Wu X, Park JB, Mabrouk ME, Schiffrin EL. Src-Dependent Erk1/2-Mediated Signaling Pathways and Associated Ang Ii-Stimulated Growth Responses Are Altered in Vascular Smooth Muscle Cells from Arteries of Hypertensive Patients. Hypertension. 36: 721-721. DOI: 10.1161/01.Hyp.36.Suppl_1.721-A  0.449
2000 Tostes RCA, Touyz RM, He G, Schiffrin EL. Improved Renal Function by Eta Receptor Blockade Is Associated with Reduced Renal Expression of Tgfβ and B FGF and Increased Activity of Mmp-2 in Shrsp Hypertension. 36: 712-712. DOI: 10.1161/01.Hyp.36.Suppl_1.712  0.352
2000 Touyz RM, He G, Wu X, Mabrouk ME, Schiffrin EL. P38 MAP Kinase Regulates Vascular Smooth Muscle Cell (VSMC) Collagen Synthesis by Ang II in Shr But not in Wky. Hypertension. 36: 707-707. DOI: 10.1161/01.Hyp.36.Suppl_1.707-D  0.415
2000 Diep QN, Mabrouk ME, Touyz RM, Schiffrin EL. Expression of Cell Cycle Proteins P21waf1/Cip1, P27kip1, Cyclin D1 and CDK4 in Blood Vessels of Angiotensin II-Infused Rats. Role of AT1 Receptors. Hypertension. 36: 707-707. DOI: 10.1161/01.Hyp.36.Suppl_1.707-B  0.423
2000 Park JB, Touyz RM, Chen X, Schiffrin EL. Tempol, Vitamin C and Vitamin E Improve Endothelial Dysfunction, Regress Vascular Hypertrophy and Prevent Progression of Hypertension and Renal Dysfunction in Stroke-Prone Shr Hypertension. 36: 699-699. DOI: 10.1161/01.Hyp.36.Suppl_1.699-B  0.4
2000 Touyz RM, Chen X, Park JB, Schiffrin EL. Attenuated Development of Hypertension by Antioxidant Vitamins in Stroke-Prone Shr Is Associated with Increased Vascular Superoxide Dismutase Activity and Decreased Oxidative Stress. Hypertension. 36: 699-699. DOI: 10.1161/01.Hyp.36.Suppl_1.699-A  0.377
2000 Touyz RM, Schiffrin EL. Increased Generation of Vascular Reactive Oxygen Species by Ang II Is Mediated Via Src-Dependent Pathways in Essential Hypertension. Hypertension. 36: 685-685. DOI: 10.1161/01.Hyp.36.Suppl_1.685-B  0.475
2000 Park JB, Schiffrin EL. Small Artery Remodeling Is the First Manifestation of Target Organ Damage in Mild Essential Hypertension. Hypertension. 36: 684-684. DOI: 10.1161/01.Hyp.36.Suppl_1.684-A  0.409
2000 Pu Q, Schiffrin EL. Effect of Vasopeptidase Inhibition on Myocardial and Vascular Collagen in Stroke Prone Spontaneously Hypertensive Rats. Hypertension. 36: 684-684. DOI: 10.1161/01.Hyp.36.Suppl_1.684  0.418
2000 Schiffrin E. The evidence for actions of angiotensin II on vascular growth Thursday, may 18, marquis ballroom, 6:30 am to 8:00 am. understanding the role of angiotensin ii in hypertension and beyond American Journal of Hypertension. 13: S331. DOI: 10.1016/S0895-7061(00)00887-6  0.445
2000 Schiffrin E. Vascular remodeling action of angiotensin II from bench to bedside Wednesday, may 17, broadway ballroom south, 9:30 am to 11:30 am. angiotensin ii: antagonism in the management of cardiovascular disease American Journal of Hypertension. 13: S327-S328. DOI: 10.1016/S0895-7061(00)00878-5  0.406
1999 Intengan HD, Thibault G, Li JS, Schiffrin EL. Resistance artery mechanics, structure, and extracellular components in spontaneously hypertensive rats : effects of angiotensin receptor antagonism and converting enzyme inhibition. Circulation. 100: 2267-75. PMID 10578002 DOI: 10.1161/01.Cir.100.22.2267  0.457
1999 Touyz RM, Schiffrin EL. Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 34: 976-82. PMID 10523394 DOI: 10.1161/01.Hyp.34.4.976  0.395
1999 Intengan HD, Park JB, Schiffrin EL. Blood pressure and small arteries in DOCA-salt-treated genetically AVP-deficient rats: role of endothelin. Hypertension (Dallas, Tex. : 1979). 34: 907-13. PMID 10523383 DOI: 10.1161/01.Hyp.34.4.907  0.453
1999 Schiffrin EL. State-of-the-Art lecture. Role of endothelin-1 in hypertension. Hypertension (Dallas, Tex. : 1979). 34: 876-81. PMID 10523377 DOI: 10.1161/01.Hyp.34.4.876  0.493
1999 Larouche I, Schiffrin EL. Cardiac microvasculature in DOCA-salt hypertensive rats : effect of endothelin ET(A) receptor antagonism. Hypertension (Dallas, Tex. : 1979). 34: 795-801. PMID 10523363 DOI: 10.1161/01.Hyp.34.4.795  0.428
1999 Diep QN, Li JS, Schiffrin EL. In vivo study of AT(1) and AT(2) angiotensin receptors in apoptosis in rat blood vessels. Hypertension (Dallas, Tex. : 1979). 34: 617-24. PMID 10523336 DOI: 10.1161/01.Hyp.34.4.617  0.408
1999 Touyz RM, Schiffrin EL. Activation of the Na(+)-H+ exchanger modulates angiotensin II-stimulated Na(+)-dependent Mg2+ transport in vascular smooth muscle cells in genetic hypertension. Hypertension (Dallas, Tex. : 1979). 34: 442-9. PMID 10489391 DOI: 10.1161/01.Hyp.34.3.442  0.358
1999 Touyz RM, Deng LY, He G, Wu XH, Schiffrin EL. Angiotensin II stimulates DNA and protein synthesis in vascular smooth muscle cells from human arteries: role of extracellular signal-regulated kinases. Journal of Hypertension. 17: 907-16. PMID 10419063 DOI: 10.1097/00004872-199917070-00006  0.403
1999 Endemann D, Touyz RM, Li JS, Deng LY, Schiffrin EL. Altered angiotensin II-induced small artery contraction during the development of hypertension in spontaneously hypertensive rats. American Journal of Hypertension. 12: 716-23. PMID 10411369 DOI: 10.1016/S0895-7061(99)00036-9  0.51
1999 Schiffrin EL, Deng LY. Relationship between small-artery structure and systolic, diastolic and pulse pressure in essential hypertension. Journal of Hypertension. 17: 381-7. PMID 10100076 DOI: 10.1097/00004872-199917030-00011  0.421
1999 Touyz RM, El Mabrouk M, He G, Wu XH, Schiffrin EL. Mitogen-activated protein/extracellular signal-regulated kinase inhibition attenuates angiotensin II-mediated signaling and contraction in spontaneously hypertensive rat vascular smooth muscle cells. Circulation Research. 84: 505-15. PMID 10082472 DOI: 10.1161/01.Res.84.5.505  0.421
1999 Intengan HD, Deng LY, Li JS, Schiffrin EL. Mechanics and composition of human subcutaneous resistance arteries in essential hypertension. Hypertension (Dallas, Tex. : 1979). 33: 569-74. PMID 9931167 DOI: 10.1161/01.Hyp.33.1.569  0.428
1999 Touyz RM, Endemann D, He G, Li JS, Schiffrin EL. Role of AT2 receptors in angiotensin II-stimulated contraction of small mesenteric arteries in young SHR. Hypertension (Dallas, Tex. : 1979). 33: 366-72. PMID 9931131 DOI: 10.1161/01.Hyp.33.1.366  0.457
1999 Touyz RM, He G, Deng LY, Schiffrin EL. Role of extracellular signal-regulated kinases in angiotensin II-stimulated contraction of smooth muscle cells from human resistance arteries. Circulation. 99: 392-9. PMID 9918526 DOI: 10.1161/01.Cir.99.3.392  0.37
1999 Intengan HD, Schiffrin EL. Mechanical properties of mesenteric resistance arteries from Dahl salt-resistant and salt-sensitive rats: role of endothelin-1. Journal of Hypertension. 16: 1907-12. PMID 9886876 DOI: 10.1097/00004872-199816121-00009  0.382
1999 Schiffrin EL. Endothelin and endothelin antagonists in hypertension. Journal of Hypertension. 16: 1891-5. PMID 9886874 DOI: 10.1097/00004872-199816121-00007  0.518
1999 Sharifi AM, Li JS, Endemann D, Schiffrin EL. Effects of enalapril and amlodipine on small-artery structure and composition, and on endothelial dysfunction in spontaneously hypertensive rats. Journal of Hypertension. 16: 457-66. PMID 9797191 DOI: 10.1097/00004872-199816040-00007  0.443
1998 Intengan HD, He G, Schiffrin EL. Effect of vasopressin antagonism on structure and mechanics of small arteries and vascular expression of endothelin-1 in deoxycorticosterone acetate salt hypertensive rats. Hypertension (Dallas, Tex. : 1979). 32: 770-7. PMID 9774378 DOI: 10.1161/01.Hyp.32.4.770  0.464
1998 Sharifi AM, Schiffrin EL. Apoptosis in vasculature of spontaneously hypertensive rats: effect of an angiotensin converting enzyme inhibitor and a calcium channel antagonist. American Journal of Hypertension. 11: 1108-16. PMID 9752897 DOI: 10.1016/S0895-7061(98)00120-4  0.399
1998 Li JS, Turgeon A, Schiffrin EL. Effect of chronic treatment with two different ET(A) selective endothelin receptor antagonists on blood pressure and small artery structure of deoxycorticosterone acetate (DOCA)-salt hypertensive rats American Journal of Hypertension. 11: 554-562. PMID 9633791 DOI: 10.1016/S0895-7061(97)00405-6  0.493
1998 Deng LY, Schiffrin EL. Endothelin-1 gene expression in blood vessels and kidney of spontaneously hypertensive rats (SHR), L-NAME-treated SHR, and renovascular hypertensive rats. Journal of Cardiovascular Pharmacology. S380-3. PMID 9595489 DOI: 10.1097/00005344-199800001-00108  0.426
1998 Sharifi AM, He G, Touyz RM, Schiffrin EL. Vascular endothelin-1 expression and effect of an endothelin ETA antagonist on structure and function of small arteries from stroke-prone spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology. S309-12. PMID 9595467 DOI: 10.1097/00005344-199800001-00086  0.434
1998 Touyz RM, Fareh J, Thibault G, Schiffrin EL. Endothelin-1 signaling is altered in cardiac cells from deoxycorticosterone acetate-salt hypertensive rats. Journal of Cardiovascular Pharmacology. S179-81. PMID 9595432 DOI: 10.1097/00005344-199800001-00051  0.388
1998 Schiffrin EL. Vascular remodeling and endothelial function in hypertensive patients: effects of antihypertensive therapy. Scandinavian Cardiovascular Journal. Supplement. 47: 15-21. PMID 9540129 DOI: 10.1080/140174398428009  0.461
1998 Li JS, Touyz RM, Schiffrin EL. Effects of AT1 and AT2 angiotensin receptor antagonists in angiotensin II-infused rats. Hypertension (Dallas, Tex. : 1979). 31: 487-92. PMID 9453350 DOI: 10.1161/01.Hyp.31.1.487  0.448
1998 Sharifi AM, Schiffrin EL. Apoptosis in aorta of deoxycorticosterone acetate-salt hypertensive rats: effect of endothelin receptor antagonism. Journal of Hypertension. 15: 1441-8. PMID 9431850 DOI: 10.1097/00004872-199715120-00011  0.435
1998 Touyz RM, Schiffrin EL. Role of calcium influx and intracellular calcium stores in angiotensin II-mediated calcium hyper-responsiveness in smooth muscle from spontaneously hypertensive rats. Journal of Hypertension. 15: 1431-9. PMID 9431849 DOI: 10.1097/00004872-199715120-00010  0.408
1998 Schiffrin EL. Structure and function of small arteries of essential hypertensive patients following chronic treatment with once-a-day nifedipine. Cardiology. 20-6. PMID 9397289 DOI: 10.1159/000177502  0.415
1997 Fareh J, Touyz RM, Schiffrin EL, Thibault G. Cardiac type-1 angiotensin II receptor status in deoxycorticosterone acetate-salt hypertension in rats. Hypertension (Dallas, Tex. : 1979). 30: 1253-9. PMID 9369284 DOI: 10.1161/01.Hyp.30.5.1253  0.463
1997 Li JS, Sharifi AM, Schiffrin EL. Effect of AT1 angiotensin-receptor blockade on structure and function of small arteries in SHR. Journal of Cardiovascular Pharmacology. 30: 75-83. PMID 9268224 DOI: 10.1097/00005344-199707000-00011  0.481
1997 Touyz RM, Schiffrin EL. Angiotensin II regulates vascular smooth muscle cell pH, contraction, and growth via tyrosine kinase-dependent signaling pathways. Hypertension (Dallas, Tex. : 1979). 30: 222-9. PMID 9260984 DOI: 10.1161/01.Hyp.30.2.222  0.415
1997 Lacroix A, Tremblay J, Touyz RM, Deng LY, Lariviere R, Cusson JR, Schiffrin EL, Hamet P. Abnormal adrenal and vascular responses to vasopressin mediated by a V1-vasopressin receptor in a patient with adrenocorticotropin-independent macronodular adrenal hyperplasia, Cushing's syndrome, and orthostatic hypotension Journal of Clinical Endocrinology and Metabolism. 82: 2414-2422. PMID 9253310 DOI: 10.1210/Jcem.82.8.4140  0.356
1997 Schiffrin EL, Turgeon A, Deng LY. Effect of chronic ETA-selective endothelin receptor antagonism on blood pressure in experimental and genetic hypertension in rats British Journal of Pharmacology. 121: 935-940. PMID 9222550 DOI: 10.1038/Sj.Bjp.0701224  0.473
1997 Schiffrin EL, Hayoz D. How to assess vascular remodelling in small and medium-sized muscular arteries in humans. Journal of Hypertension. 15: 571-84. PMID 9218175 DOI: 10.1097/00004872-199715060-00002  0.385
1997 Laurant P, Touyz RM, Schiffrin EL. Effect of pressurization on mechanical properties of mesenteric small arteries from spontaneously hypertensive rats. Journal of Vascular Research. 34: 117-25. PMID 9167644 DOI: 10.1159/000159209  0.392
1997 Methot D, LaPointe MC, Touyz RM, Yang XP, Carretero OA, Deschepper CF, Schiffrin EL, Thibault G, Reudelhuber TL. Tissue targeting of angiotensin peptides Journal of Biological Chemistry. 272: 12994-12999. PMID 9148907 DOI: 10.1074/Jbc.272.20.12994  0.338
1997 Schiffrin EL, Lariviere R, Touyz RM. ETA and ETB receptors on vascular smooth muscle cells from mesenteric vessels of spontaneously hypertensive rats. Clinical and Experimental Pharmacology & Physiology. Supplement. 22: S193-4. PMID 9072351 DOI: 10.1111/J.1440-1681.1995.Tb02877.X  0.413
1997 Schiffrin EL, Lariviere R, Li JS, Sventek P, Touyz RM. Endothelin-1 gene expression and vascular hypertrophy in DOCA-salt hypertension compared to spontaneously hypertensive rats. Clinical and Experimental Pharmacology & Physiology. Supplement. 22: S188-90. PMID 9072349 DOI: 10.1111/J.1440-1681.1995.Tb02875.X  0.48
1997 Schiffrin EL, Deng LY, Sventek P, Day R. Enhanced expression of endothelin-1 gene in resistance arteries in severe human essential hypertension. Journal of Hypertension. 15: 57-63. PMID 9050971 DOI: 10.1097/00004872-199715010-00005  0.45
1997 Li JS, Schiffrin EL. Effect of short-term treatment of SHR with the novel calcium channel antagonist mibefradil on function of small arteries. American Journal of Hypertension. 10: 94-100. PMID 9008253 DOI: 10.1016/S0895-7061(96)00294-4  0.415
1997 Touyz RM, Schiffrin EL. Treatment of non-insulin-dependent diabetic hypertensive patients with Ca2+ channel blockers is associated with increased platelet sensitivity to insulin. American Journal of Hypertension. 8: 1214-21. PMID 8998256 DOI: 10.1016/0895-7061(95)00249-9  0.309
1997 Sventek P, Turgeon A, Schiffrin EL. Vascular endothelin-1 gene expression and effect on blood pressure of chronic ET(A) endothelin receptor antagonism after nitric oxide synthase inhibition with L-NAME in normal rats Circulation. 95: 240-244. PMID 8994442 DOI: 10.1161/01.Cir.95.1.240  0.418
1997 Schiffrin EL. The endothelium of resistance arteries: physiology and role in hypertension. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 54: 17-25. PMID 8992488 DOI: 10.1016/S0952-3278(96)90076-9  0.31
1997 Schiffrin EL, Deng LY. Structure and function of resistance arteries of hypertensive patients treated with a beta-blocker or a calcium channel antagonist. Journal of Hypertension. 14: 1247-55. PMID 8906525 DOI: 10.1097/00004872-199610000-00014  0.302
1997 Singh A, Sventek P, Larivière R, Thibault G, Schiffrin EL. Inducible nitric oxide synthase in vascular smooth muscle cells from prehypertensive spontaneously hypertensive rats. American Journal of Hypertension. 9: 867-77. PMID 8879343 DOI: 10.1016/S0895-7061(96)00104-5  0.357
1997 Li JS, Schürch W, Schiffrin EL. Renal and vascular effects of chronic endothelin receptor antagonism in malignant hypertensive rats. American Journal of Hypertension. 9: 803-11. PMID 8862227 DOI: 10.1016/0895-7061(96)00100-8  0.47
1997 Li JS, Schiffrin EL. Effect of calcium channel blockade or angiotensin-converting enzyme inhibition on structure of coronary, renal, and other small arteries in spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology. 28: 68-74. PMID 8797138 DOI: 10.1097/00005344-199607000-00011  0.447
1997 Laurant P, Touyz RM, Schiffrin EL. Effect of magnesium on vascular tone and reactivity in pressurized mesenteric resistance arteries from spontaneously hypertensive rats Canadian Journal of Physiology and Pharmacology. 75: 293-300. DOI: 10.1139/Y97-044  0.454
1997 Schiffrin EL, Intengan HD, Thibault G, Touyz RM. Clinical significance of endothelin in cardiovascular disease Current Opinion in Cardiology. 12: 354-367. DOI: 10.1097/00001573-199707000-00003  0.477
1997 SCHIFFRIN E. Endothelin, role in hypertension and vascular hypertrophy American Journal of Hypertension. 10: 222A. DOI: 10.1016/S0895-7061(97)89463-0  0.362
1996 Yang XP, Touyz RM, Nguyen PV, Deng LY, Li JS, Schiffrin EL. Endothelin-1 and vasopressin signalling in blood vessels of young SHR in comparison to adult SHR. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 19: 121-32. PMID 10968205 DOI: 10.1291/Hypres.19.121  0.435
1996 Schiffrin EL, Larivière R, Li JS, Sventek P. Enhanced expression of the endothelin-1 gene in blood vessels of DOCA-salt hypertensive rats: correlation with vascular structure. Journal of Vascular Research. 33: 235-48. PMID 8924521 DOI: 10.1159/000159151  0.475
1996 Touyz RM, Fareh J, Thibault G, Schiffrin EL. Intracellular Ca2+ modulation by angiotensin II and endothelin-1 in cardiomyocytes and fibroblasts from hypertrophied hearts of spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 28: 797-805. PMID 8901826 DOI: 10.1161/01.Hyp.28.5.797  0.455
1996 Touyz RM, Schiffrin EL. Angiotensin II and vasopressin modulate intracellular free magnesium in vascular smooth muscle cells through Na+-dependent protein kinase C pathways. The Journal of Biological Chemistry. 271: 24353-8. PMID 8798689 DOI: 10.1074/Jbc.271.40.24353  0.349
1996 Touyz RM, Fareh J, Thibault G, Tolloczko B, Larivière R, Schiffrin EL. Modulation of Ca2+ transients in neonatal and adult rat cardiomyocytes by angiotensin II and endothelin-1. The American Journal of Physiology. 270: H857-68. PMID 8780179 DOI: 10.1152/Ajpheart.1996.270.3.H857  0.381
1996 Li JS, Knafo L, Turgeon A, Garcia R, Schiffrin EL. Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats American Journal of Physiology - Heart and Circulatory Physiology. 271. PMID 8760162 DOI: 10.1152/Ajpheart.1996.271.1.H88  0.479
1996 Schiffrin EL. Correction of remodeling and function of small arteries in human hypertension by cilazapril, an angiotensin I-converting enzyme inhibitor. Journal of Cardiovascular Pharmacology. S13-8. PMID 8723394 DOI: 10.1097/00005344-199600002-00004  0.424
1996 Li JS, Deng LY, Grove K, Deschepper CF, Schiffrin EL. Comparison of effect of endothelin antagonism and angiotensin- converting enzyme inhibition on blood pressure and vascular structure in spontaneously hypertensive rats treated with N(ω)-nitro-L-arginine methyl ester: Correlation with topography of vascular endothelin-1 gene expression Hypertension. 28: 188-195. PMID 8707380 DOI: 10.1161/01.Hyp.28.2.188  0.429
1996 Marcil J, Schiffrin EL, Anand-Srivastava MB. Aberrant adenylyl cyclase/cAMP signal transduction and G protein levels in platelets from hypertensive patients improve with antihypertensive drug therapy. Hypertension (Dallas, Tex. : 1979). 28: 83-90. PMID 8675269 DOI: 10.1161/01.Hyp.28.1.83  0.347
1996 Touyz RM, Schiffrin EL. Tyrosine kinase signaling pathways modulate angiotensin II-induced calcium ([Ca2+]i) transients in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 27: 1097-103. PMID 8621202 DOI: 10.1161/01.Hyp.27.5.1097  0.367
1996 Touyz RM, Sventek P, Larivière R, Thibault G, Fareh J, Reudelhuber T, Schiffrin EL. Cytosolic calcium changes induced by angiotensin II in neonatal rat atrial and ventricular cardiomyocytes are mediated via angiotensin II subtype 1 receptors. Hypertension (Dallas, Tex. : 1979). 27: 1090-6. PMID 8621201 DOI: 10.1161/01.Hyp.27.5.1090  0.391
1996 Sventek P, Li JS, Grove K, Deschepper CF, Schiffrin EL. Vascular structure and expression of endothelin-1 gene in L-NAME-treated spontaneously hypertensive rats Hypertension. 27: 49-55. PMID 8591887 DOI: 10.1161/01.Hyp.27.1.49  0.455
1996 Larivière R, Deng LY, Day R, Sventek P, Thibault G, Schiffrin EL. Increased endothelin-1 gene expression in the endothelium of coronary arteries and endocardium in the DOCA-salt hypertensive rat. Journal of Molecular and Cellular Cardiology. 27: 2123-31. PMID 8576929 DOI: 10.1016/S0022-2828(95)91263-0  0.435
1996 Fareh J, Touyz RM, Schiffrin EL, Thibault G. Endothelin-1 and angiotensin II receptors in cells from rat hypertrophied heart. Receptor regulation and intracellular Ca2+ modulation. Circulation Research. 78: 302-11. PMID 8575074 DOI: 10.1161/01.Res.78.2.302  0.395
1996 Schiffrin EL. Vascular structure in NG-nitro-L-arginine methyl ester-induced hypertension: methodological considerations for studies of small arteries in hypertension. Journal of Hypertension. 13: 817-21. PMID 8557958 DOI: 10.1097/00004872-199508000-00001  0.416
1996 Fareh J, Touyz RM, Thibault G, Schiffrin EL. Basal and angiotensin II-induced cytosolic free calcium in adult rat cardiomyocytes and fibroblasts after volume overload. Hypertension (Dallas, Tex. : 1979). 26: 1149-53. PMID 7498986 DOI: 10.1161/01.Hyp.26.6.1149  0.341
1996 Touyz RM, Deng LY, Schiffrin EL. Endothelin subtype B receptor-mediated calcium and contractile responses in small arteries of hypertensive rats. Hypertension (Dallas, Tex. : 1979). 26: 1041-5. PMID 7498964 DOI: 10.1161/01.Hyp.26.6.1041  0.431
1996 Sharifi AM, Schiffrin EL. Endothelin receptors mediating vasoconstriction in rat pressurized small arteries Canadian Journal of Physiology and Pharmacology. 74: 934-939. DOI: 10.1139/Y96-085  0.317
1996 Touyz RM, Deng L, Li J, Schiffrin EL. Differential effects of vasopressin and endothelin-1 on vascular contractile and calcium responses in pressurized small arteries from spontaneously hypertensive rats Journal of Hypertension. 14: 983???992. DOI: 10.1097/00004872-199715080-00016  0.392
1996 Sventek P, Turgeon A, Garc??a R, Schiffrin EL. Vascular and cardiac overexpression of endothelin-1 gene in one-kidney, one clip Goldblatt hypertensive rats but only in the late phase of two-kidney one clip Goldblatt hypertension Journal of Hypertension. 14: 57???64. DOI: 10.1097/00004872-199601000-00008  0.457
1995 Touyz RM, Lariviere R, Schiffrin EL. Endothelin receptor subtypes in mesenteric vascular smooth muscle cells of spontaneously hypertensive rats Canadian Journal of Physiology and Pharmacology. 73: 1262-1273. PMID 8748975 DOI: 10.1139/Y95-178  0.385
1995 Schiffrin EL, Sventek P, Li JS, Turgeon A, Reudelhuber T. Antihypertensive effect of an endothelin receptor antagonist in DOCA-salt spontaneously hypertensive rats British Journal of Pharmacology. 115: 1377-1381. PMID 8564194 DOI: 10.1111/J.1476-5381.1995.Tb16626.X  0.475
1995 Schiffrin EL. Intracellular signal transduction for vasoactive peptides in hypertension. Canadian Journal of Physiology and Pharmacology. 72: 954-62. PMID 7834583 DOI: 10.1139/Y94-133  0.46
1995 Day R, Larivière R, Schiffrin EL. In situ hybridization shows increased endothelin-1 mRNA levels in endothelial cells of blood vessels of deoxycorticosterone acetate-salt hypertensive rats. American Journal of Hypertension. 8: 294-300. PMID 7794580 DOI: 10.1016/0895-7061(95)96213-4  0.475
1995 Schiffrin EL, Deng LY, Larochelle P. Progressive improvement in the structure of resistance arteries of hypertensive patients after 2 years of treatment with an angiotensin I-converting enzyme inhibitor. Comparison with effects of a beta-blocker. American Journal of Hypertension. 8: 229-36. PMID 7794571 DOI: 10.1016/0895-7061(95)96211-2  0.381
1995 Schiffrin EL. Endothelin: potential role in hypertension and vascular hypertrophy. Hypertension (Dallas, Tex. : 1979). 25: 1135-43. PMID 7768553 DOI: 10.1161/01.Hyp.25.6.1135  0.494
1995 Touyz RM, Tolloczko B, Schiffrin EL. Blunted attenuation of angiotensin II-mediated Ca2+ transients by insulin in cultured unpassaged vascular smooth muscle cells from spontaneously hypertensive rats. American Journal of Hypertension. 8: 104-12. PMID 7755938 DOI: 10.1016/0895-7061(94)00173-9  0.398
1995 Larivière R, Sventek P, Schiffrin EL. Expression of endothelin-1 gene in blood vessels of adult spontaneously hypertensive rats. Life Sciences. 56: 1889-96. PMID 7746097 DOI: 10.1016/0024-3205(95)00163-Z  0.482
1995 Schiffrin EL, Lariviere R, Li JS, Sventek P, Touyz RM. Deoxycorticosterone acetate plus salt induces overexpression of vascular endothelin-1 and severe vascular hypertrophy in spontaneously hypertensive rats Hypertension. 25: 769-773. PMID 7721430 DOI: 10.1161/01.Hyp.25.4.769  0.476
1995 Schiffrin EL, Deng LY. Comparison of effects of angiotensin I-converting enzyme inhibition and beta-blockade for 2 years on function of small arteries from hypertensive patients. Hypertension (Dallas, Tex. : 1979). 25: 699-703. PMID 7721419 DOI: 10.1161/01.Hyp.25.4.699  0.387
1995 Li JS, Schiffrin EL. Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin receptor antagonist. Hypertension (Dallas, Tex. : 1979). 25: 495-500. PMID 7721389 DOI: 10.1161/01.Hyp.25.4.495  0.49
1995 Schiffrin EL. Remodeling of resistance arteries in human hypertension: effects of cilazapril, an angiotensin-I-converting enzyme inhibitor. Cardiology. 16-22. PMID 7614501 DOI: 10.1159/000176941  0.436
1995 Li JS, Schiffrin EL. Chronic endothelin receptor antagonist treatment of young spontaneously hypertensive rats. Journal of Hypertension. 13: 647-52. PMID 7594422 DOI: 10.1097/00004872-199506000-00011  0.442
1995 Lee RM, Owens GK, Scott-Burden T, Head RJ, Mulvany MJ, Schiffrin EL. Pathophysiology of smooth muscle in hypertension. Canadian Journal of Physiology and Pharmacology. 73: 574-84. PMID 7585323 DOI: 10.1139/Y95-073  0.426
1995 Lariviere R, Sventek P, Thibault G, Schiffrin EL. Endothelin-1 expression in blood vessels of DOCA-salt hypertensive rats treated with the combined ET(A)/ET(B) endothelin receptor antagonist bosentan Canadian Journal of Physiology and Pharmacology. 73: 390-398. PMID 7544236 DOI: 10.1139/Y95-050  0.436
1995 Deng LY, Li JS, Schiffrin EL. Endothelium-dependent relaxation of small arteries from essential hypertensive patients: mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats. Clinical Science (London, England : 1979). 88: 611-22. PMID 7543395 DOI: 10.1042/Cs0880611  0.436
1995 Li JS, Schiffrin EL. Resistance artery structure and neuroeffector mechanisms in hypertension induced by inhibition of nitric oxide synthase. American Journal of Hypertension. 7: 996-1004. PMID 7531459 DOI: 10.1093/Ajh/7.11.996  0.336
1995 Schiffrin EL, Larivière R, Li J, Sventek P, Touyz RM. Enhanced Expression of Endothelin-1 Gene May Cause Blood Pressure-Independent Vascular Hypertrophy Journal of Cardiovascular Pharmacology. 26: S5-8. DOI: 10.1097/00005344-199506263-00003  0.466
1995 Schiffrin EL. Endothelin in hypertension Current Opinion in Cardiology. 10: 493-494. DOI: 10.1097/00001573-199509000-00008  0.506
1995 Deng L, Li J, Schiffrin EL. Endothelin receptor subtypes in resistance arteries from humans and rats Cardiovascular Research. 29: 532-535. DOI: 10.1016/S0008-6363(96)88530-0  0.409
1995 SCHIFFRIN E. Vascular remodeling and endothelin antagonism in hypertension American Journal of Hypertension. 8: 19A. DOI: 10.1016/0895-7061(95)97444-V  0.466
1994 Schiffrin EL, Deng LY, Larochelle P. Effects of a beta-blocker or a converting enzyme inhibitor on resistance arteries in essential hypertension. Hypertension. 23: 83-91. PMID 8282334 DOI: 10.1161/01.Hyp.23.1.83  0.376
1994 Touyz RM, Schiffrin EL. Effects of angiotensin II and endothelin-1 on platelet aggregation and cytosolic pH and free Ca2+ concentrations in essential hypertension. Hypertension (Dallas, Tex. : 1979). 22: 853-62. PMID 8244517 DOI: 10.1161/01.Hyp.22.6.853  0.396
1994 Touyz RM, Schiffrin EL. Insulin-induced Ca2+ transport is altered in vascular smooth muscle cells of spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 23: 931-5. PMID 8206630 DOI: 10.1161/01.Hyp.23.6.931  0.329
1994 Deschepper CF, Li JS, Schiffrin EL, Welner SA. Hypertension induced by brain grafts from fetal spontaneously hypertensive rats Hypertension. 23: 765-773. PMID 8206575 DOI: 10.1161/01.Hyp.23.6.765  0.355
1994 Larochelle P, Cusson JR, du Souich P, Hamet P, Schiffrin EL. Renal effects of immersion in essential hypertension. Carvedilol Study Group. American Journal of Hypertension. 7: 120-8. PMID 8179847 DOI: 10.1093/Ajh/7.2.120  0.339
1994 Li JS, Larivière R, Schiffrin EL. Effect of a nonselective endothelin antagonist on vascular remodeling in deoxycorticosterone acetate-salt hypertensive rats. Evidence for a role of endothelin in vascular hypertrophy. Hypertension (Dallas, Tex. : 1979). 24: 183-8. PMID 8039842 DOI: 10.1161/01.Hyp.24.2.183  0.48
1994 Touyz RM, Schiffrin EL. Signal transduction in hypertension: Part I. Current Opinion in Nephrology and Hypertension. 2: 5-16. PMID 7922167 DOI: 10.1097/00041552-199301000-00003  0.394
1994 Schiffrin EL, Deng LY, Larochelle P. Effects of Antihypertensive Treatment on Vascular Remodeling in Essential Hypertensive Patients Journal of Cardiovascular Pharmacology. 24: 557. DOI: 10.1097/00005344-199400243-00009  0.446
1994 Touyz RM, Schiffrin EL. Blunted inhibition by insulin of agonist-stimulated calcium, pH and aggregatory responses in platelets from hypertensive patients Journal of Hypertension. 12: 1255???1264. DOI: 10.1097/00004872-199411000-00008  0.33
1994 Touyz RM, Tolloczko B, Schiffrin EL. Mesenteric vascular smooth muscle cells from spontaneously hypertensive rats display increased calcium responses to angiotensin II but not to endothelin-1 Journal of Hypertension. 12: 663???674. DOI: 10.1097/00004872-199406000-00006  0.417
1993 Larivière R, Day R, Schiffrin EL. Increased expression of endothelin-1 gene in blood vessels of deoxycorticosterone acetate-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979). 21: 916-20. PMID 8505101 DOI: 10.1161/01.Hyp.21.6.916  0.451
1993 Lariviere R, Thibault G, Schiffrin EL. Increased endothelin-1 content in blood vessels of deoxycorticosterone acetate-salt hypertensive but not in spontaneously hypertensive rats Hypertension. 21: 294-300. PMID 8478038 DOI: 10.1161/01.Hyp.21.3.294  0.469
1993 Touyz RM, Schiffrin EL. The effect of angiotensin II on platelet intracellular free magnesium and calcium ionic concentrations in essential hypertension. Journal of Hypertension. 11: 551-8. PMID 8390527 DOI: 10.1097/00004872-199305000-00011  0.377
1993 Nguyen PV, Yang XP, Li G, Deng LY, Flückiger JP, Schiffrin EL. Contractile responses and signal transduction of endothelin-1 in aorta and mesenteric vasculature of adult spontaneously hypertensive rats. Canadian Journal of Physiology and Pharmacology. 71: 473-83. PMID 8242481 DOI: 10.1139/Y93-069  0.415
1993 Deng LY, Schiffrin EL. Effect of antihypertensive treatment on response to endothelin of resistance arteries of hypertensive rats. Journal of Cardiovascular Pharmacology. 21: 725-31. PMID 7685441 DOI: 10.1097/00005344-199305000-00006  0.432
1993 Deng LY, Thibault G, Schiffrin EL. Effect of hypertension induced by nitric oxide synthase inhibition on structure and function of resistance arteries in the rat. Clinical and Experimental Hypertension (New York, N.Y. : 1993). 15: 527-37. PMID 7683950 DOI: 10.3109/10641969309041627  0.443
1993 Deng LY, Schiffrin EL. Effects of endothelin-1 and vasopressin on resistance arteries of spontaneously hypertensive rats. American Journal of Hypertension. 5: 817-22. PMID 1457083 DOI: 10.1093/Ajh/5.11.817  0.449
1993 Garcia R, Bonhomme MC, Schiffrin EL. Divergent regulation of atrial natriuretic factor receptors in high-output heart failure. The American Journal of Physiology. 263: H1790-7. PMID 1336315 DOI: 10.1152/Ajpheart.1992.263.6.H1790  0.375
1993 Touyz R, Schiffrin EL. Biology of Blood Vessels in Hypertension Cardiology in Review. 1: 87-96. DOI: 10.1097/00045415-199301020-00004  0.428
1992 Schiffrin EL. Reactivity of small blood vessels in hypertension: relation with structural changes. State of the art lecture. Hypertension (Dallas, Tex. : 1979). 19: II1-9. PMID 1735561 DOI: 10.1161/01.HYP.19.2_Suppl.II1-a  0.353
1992 Deng LY, Schiffrin EL. Effects of endothelin on resistance arteries of DOCA-salt hypertensive rats. The American Journal of Physiology. 262: H1782-7. PMID 1621836 DOI: 10.1152/ajpheart.1992.262.6.H1782  0.372
1992 Schiffrin EL, Parent A, St Louis J, Tremblay J, Garcia R, Thibault G. Vascular atrial natriuretic factor receptors in spontaneously hypertensive rats Cardiovascular Research. 26: 857-864. PMID 1360334 DOI: 10.1093/Cvr/26.9.857  0.431
1992 Parent A, Nguyen PV, Yang XP, Schiffrin EL. Inositol phosphate production in response to [Arg8]vasopressin, endothelin 1, and prostaglandin F2 alpha in rat aorta and mesenteric arteries. Canadian Journal of Physiology and Pharmacology. 70: 1408-16. PMID 1337016 DOI: 10.1139/Y92-198  0.345
1992 Schiffrin EL, Deng LY, Larochelle P. Blunted effects of endothelin upon small subcutaneous resistance arteries of mild essential hypertensive patients. Journal of Hypertension. 10: 437-44. PMID 1317904 DOI: 10.1097/00004872-199205000-00006  0.417
1992 Flückiger JP, Nguyen PV, Li G, Yang XP, Schiffrin EL. Calcium, phosphoinositide, and 1,2-diacylglycerol responses of blood vessels of deoxycorticosterone acetate-salt hypertensive rats to endothelin-1. Hypertension. 19: 743-8. PMID 1317355 DOI: 10.1161/01.Hyp.19.6.743  0.403
1992 Nguyen PV, Parent A, Deng LY, Flückiger JP, Thibault G, Schiffrin EL. Endothelin vascular receptors and responses in deoxycorticosterone acetate-salt hypertensive rats. Hypertension. 19: II98-104. PMID 1310486 DOI: 10.1161/01.Hyp.19.2_Suppl.Ii98  0.454
1991 Schiffrin EL. Regulation of receptors for atrial natriuretic peptide in the rat and human. Cardiovascular Drugs and Therapy. 2: 493-500. PMID 2856469 DOI: 10.1007/BF00051188  0.312
1991 Schiffrin EL. Vascular receptors for atrial natriuretic peptide in hypertension. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 17: 673-6. PMID 2175736 DOI: 10.1016/0883-2897(90)90083-D  0.475
1991 Schiffrin EL, Thibault G. Plasma endothelin in human essential hypertension. American Journal of Hypertension. 4: 303-8. PMID 2059394 DOI: 10.1093/Ajh/4.4.303  0.408
1991 Cachofeiro V, Schiffrin EL, Cantin M, Garcia R. Glomerular and vascular atrial natriuretic factor receptors in cardiomyopathic hamsters: correlation with the peptide biological effects. Cardiovascular Research. 24: 843-50. PMID 1964873 DOI: 10.1093/Cvr/24.10.843  0.33
1991 Cachofeiro V, Schiffrin EL, Bonhomme MC, Cantin M, Garcia R. In vivo heterologous regulation of rat glomerular and vascular atrial natriuretic factor receptors by angiotensin II. Journal of Hypertension. 8: 1077-83. PMID 1962795 DOI: 10.1097/00004872-199012000-00002  0.434
1991 Schiffrin EL, Turgeon A, Tremblay J, Deslongchamps M. Effects of ANP, angiotensin, vasopressin, and endothelin on ANP receptors in cultured rat vascular smooth muscle cells American Journal of Physiology - Heart and Circulatory Physiology. 260. PMID 1847018 DOI: 10.1152/Ajpheart.1991.260.1.H58  0.421
1991 Schiffrin EL, Carrier F, Thibault G, Deslongchamps M. Solubilization and molecular characterization of the atrial natriuretic peptide (ANP) receptor in human platelets: comparison with ANP receptors in rat tissues. The Journal of Clinical Endocrinology and Metabolism. 72: 484-91. PMID 1846877 DOI: 10.1210/Jcem-72-2-484  0.356
1991 Parent A, Schiffrin EL, St-Louis J. Receptors for Arg8-vasopressin, angiotensin II, and atrial natriuretic peptide in the mesenteric vasculature of pregnant rats Canadian Journal of Physiology and Pharmacology. 69: 137-144. PMID 1647264 DOI: 10.1139/Y91-020  0.401
1990 Schiffrin EL. Vascular receptors for angiotensin, vasopressin, and atrial natriuretic peptide in experimental hypertension. Canadian Journal of Physiology and Pharmacology. 67: 1118-23. PMID 2557150 DOI: 10.1139/Y89-178  0.489
1990 Parent A, Schiffrin EL, St-Louis J. Role of the endothelium in adrenergic responses of mesenteric artery rings of pregnant rats American Journal of Obstetrics and Gynecology. 163: 229-234. PMID 2375347 DOI: 10.1016/S0002-9378(11)90703-0  0.358
1990 Massicotte G, Coderre L, Chiasson JL, Thibault G, Schiffrin EL, St-Louis J. Regulation of ANG II and AVP receptors in isolated hepatocytes of pregnant rats. The American Journal of Physiology. 258: E597-605. PMID 2333959 DOI: 10.1152/Ajpendo.1990.258.4.E597  0.404
1990 Nuglozeh E, Gauquelin G, Garcia R, Tremblay J, Schiffrin EL. Atrial natriuretic peptide receptors in renal papilla of DOCA-salt hypertensive rats. The American Journal of Physiology. 259: F130-7. PMID 2165357 DOI: 10.1152/Ajprenal.1990.259.1.F130  0.303
1989 St-Louis J, Schiffrin EL. Vasorelaxant effects of and receptors for atrial natriuretic peptides in the mesenteric artery and aorta of the rat. Canadian Journal of Physiology and Pharmacology. 66: 951-6. PMID 2850846 DOI: 10.1139/Y88-155  0.345
1989 Gauquelin G, Schiffrin EL, Garcia R, Entresangles M, Cantin M, Gharib C. Specific binding of atrial natriuretic factor to renal glomeruli during day or night antiorthostatic suspension in the rat. Life Sciences. 43: 1905-12. PMID 2849010 DOI: 10.1016/S0024-3205(88)80008-0  0.341
1989 Garcia R, Gauquelin G, Thibault G, Cantin M, Schiffrin EL. Glomerular atrial natriuretic factor receptors in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 13: 567-74. PMID 2544518 DOI: 10.1161/01.Hyp.13.6.567  0.398
1989 Cachofeiro V, Schiffrin EL, Cantin M, Garcia R. Glomerular and vascular atrial natriuretic factor receptors in adrenalectomized rats. The American Journal of Physiology. 256: R1250-7. PMID 2544113 DOI: 10.1152/ajpregu.1989.256.6.R1250  0.317
1989 Lariviere R, Baribeau J, St-Louis J, Schiffrin EL. Vasopressin receptors and inositol trisphosphate production in blood vessels of spontaneously hypertensive rats Canadian Journal of Physiology and Pharmacology. 67: 232-239. PMID 2525949 DOI: 10.1139/Y89-039  0.449
1989 Cachofeiro V, Schiffrin EL, Thibault G, Cantin M, Garcia R. Effect of a chronic infusion of atrial natriuretic factor on glomerular and vascular receptors in spontaneously hypertensive rats Journal of Hypertension. 7: 335???342. DOI: 10.1097/00004872-198904000-00015  0.456
1988 Larivière R, St-Louis J, Schiffrin EL. Vascular binding sites and biological activity of vasopressin in DOCA-salt hypertensive rats. Journal of Hypertension. 6: 211-7. PMID 3283226 DOI: 10.1097/00004872-198803000-00005  0.448
1988 Lariviere R, St-Louis J, Schiffrin EL. Vascular vasopressin receptors in renal hypertensive rats American Journal of Physiology - Heart and Circulatory Physiology. 255. PMID 2972216 DOI: 10.1152/Ajpheart.1988.255.4.H693  0.412
1988 Cantin M, Garcia R, Thibault G, Kuchel O, Gutkowska J, Larochelle P, Hamet P, Schiffrin EL, Genest J. Atrial natriuretic factor in experimental and human hypertension. European Heart Journal. 9: 21-7. PMID 2971539 DOI: 10.1093/Eurheartj/9.Suppl_H.21  0.401
1988 Gauquelin G, Schiffrin EL, Cantin M, Garcia R. Atrial natriuretic factor: specific binding to renal glomeruli during the development of two-kidney, one clip hypertension in the rat. Journal of Hypertension. 6: 587-92. PMID 2844891 DOI: 10.1097/00004872-198807000-00011  0.409
1988 Schiffrin EL, St-Louis J, Essiambre R. Platelet binding sites and plasma concentration of atrial natriuretic peptide in patients with essential hypertension. Journal of Hypertension. 6: 565-72. PMID 2844890 DOI: 10.1097/00004872-198807000-00008  0.327
1988 Garcia R, Gauquelin G, Cantin M, Schiffrin EL. Glomerular and vascular atrial natriuretic factor receptors in saralasin-sensitive and -resistant two-kidney, one-clip hypertensive rats. Circulation Research. 63: 563-71. PMID 2842085 DOI: 10.1161/01.Res.63.3.563  0.465
1988 St-Louis J, Parent A, Gutkowska J, Genest J, Schiffrin EL. Vasorelaxation and vascular binding sites for atrial natriuretic peptide in pregnant rats American Journal of Physiology - Heart and Circulatory Physiology. 254: 23/6. PMID 2837912 DOI: 10.1152/Ajpheart.1988.254.6.H1027  0.348
1988 Garcia R, Gauquelin G, Cantin M, Schiffrin EL. Renal glomerular atrial natriuretic factor receptors in one-kidney, one clip rats. Hypertension (Dallas, Tex. : 1979). 11: 185-90. PMID 2830190 DOI: 10.1161/01.Hyp.11.2.185  0.406
1987 Massicotte G, St-Louis J, Parent A, Schiffrin EL. Decreased in vitro responses to vasoconstrictors during gestation in normotensive and spontaneously hypertensive rats. Canadian Journal of Physiology and Pharmacology. 65: 2466-71. PMID 3449203 DOI: 10.1139/Y87-391  0.435
1987 Massicotte G, St-Louis J, Schiffrin EL. Heart rate reflex responses during gestation in normotensive and spontaneously hypertensive rats following angiotensin II and vasopressin. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 186: 294-8. PMID 3423017 DOI: 10.3181/00379727-186-42616  0.419
1987 Gauquelin G, Schiffrin EL, Cantin M, Garcia R. Specific binding of atrial natriuretic factor to renal glomeruli in Doca- and Doca-salt-treated rats correlation with atrial and plasma levels. Biochemical and Biophysical Research Communications. 145: 522-31. PMID 3036134 DOI: 10.1016/0006-291X(87)91352-0  0.407
1987 Schiffrin EL, St-Louis J. Decreased density of vascular receptors for atrial natriuretic peptide in DOCA-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979). 9: 504-12. PMID 3032791 DOI: 10.1161/01.HYP.9.5.504  0.38
1987 Larochelle P, Cusson JR, Gutkowska J, Schiffrin EL, Hamet P, Kuchel O, Genest J, Cantin M. Plasma atrial natriuretic factor concentrations in essential and renovascular hypertension. British Medical Journal (Clinical Research Ed.). 294: 1249-52. PMID 2954611 DOI: 10.1136/Bmj.294.6582.1249  0.338
1987 Chartier L, Schiffrin EL. Atrial natriuretic peptide inhibits the effect of endogenous angiotensin II on plasma aldosterone in conscious sodium-depleted rats. Clinical Science (London, England : 1979). 72: 31-5. PMID 2948755 DOI: 10.1042/Cs0720031  0.357
1986 St-Louis J, Parent A, Lariviere R, Schiffrin EL. Vasopressin responses and receptors in the mesenteric vasculature of estrogen-treated rats American Journal of Physiology - Heart and Circulatory Physiology. 251: 20/5. PMID 3777197 DOI: 10.1152/Ajpheart.1986.251.5.H885  0.351
1986 Chartier L, Schiffrin EL. Atrial natriuretic peptide inhibits the stimulation of aldosterone secretion by ACTH in vitro and in vivo. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 182: 132-6. PMID 3008159 DOI: 10.3181/00379727-182-1-Rc2  0.348
1986 Schiffrin EL, Franks DJ, Gutkowska J. Effect of aldosterone on vascular angiotensin II receptors in the rat. Canadian Journal of Physiology and Pharmacology. 63: 1522-7. PMID 3006895 DOI: 10.1139/Y85-250  0.434
1986 Schiffrin EL, Poissant L, Cantin M, Thibault G. Receptors for atrial natriuretic factor in cultured vascular smooth muscle cells. Life Sciences. 38: 817-26. PMID 3005795 DOI: 10.1016/0024-3205(86)90598-9  0.371
1986 Murthy KK, Thibault G, Schiffrin EL, Garcia R, Chartier L, Gutkowska J, Genest J, Cantin M. Disappearance of atrial natriuretic factor from circulation in the rat. Peptides. 7: 241-6. PMID 2942845 DOI: 10.1016/0196-9781(86)90220-2  0.315
1986 Garcia R, Cantin M, De Léan A, Genest J, Godin J, Gutkowska J, Schiffrin EL, Thibault G. Comparative biological activities of ANF (Arg 101-Tyr 126) and the synthetic form of circulating ANF (Ser 99-Tyr 126). Biochemical and Biophysical Research Communications. 135: 987-93. PMID 2938586 DOI: 10.1016/0006-291X(86)91025-9  0.342
1986 Massicotte G, St-louis J, Schiffrin EL. Blood pressure effects of angiotensin II and vasopressin in conscious pregnant normotensive and spontaneously hypertensive rats Hypertension in Pregnancy. 5: 135-158. DOI: 10.3109/10641958609069090  0.369
1986 Cusson JR, Hamet P, Gutkowska J, Kuchel O, Schiffrin EL, du Souich P, Genest J, Cantin M, Larochelle P. Pharmacodynamics of Infusions of ANF in Normotensive and Hypertensive Subjects Journal of Cardiovascular Pharmacology. 8: 1293. DOI: 10.1097/00005344-198611000-00055  0.368
1985 Thibault G, Lazure C, Schiffrin EL, Gutkowska J, Chartier L, Garcia R, Seidah NG, Chrétien M, Genest J, Cantin M. Identification of a biologically active circulating form of rat atrial natriuretic factor. Biochemical and Biophysical Research Communications. 130: 981-6. PMID 3161512 DOI: 10.1016/0006-291X(85)91711-5  0.321
1985 Carrier F, Thibault G, Schiffrin EL, Garcia R, Gutkowska J, Cantin M, Genest J. Partial characterization and solubilization of receptors for atrial natriuretic factor in rat glomeruli. Biochemical and Biophysical Research Communications. 132: 666-73. PMID 2998377 DOI: 10.1016/0006-291X(85)91184-2  0.345
1985 Schiffrin EL, Chartier L, Thibault G, St-Louis J, Cantin M, Genest J. Vascular and adrenal receptors for atrial natriuretic factor in the rat. Circulation Research. 56: 801-7. PMID 2408776 DOI: 10.1161/01.Res.56.6.801  0.395
1984 Chartier L, Schiffrin E, Thibault G. Effect of atrial natriuretic factor (ANF)-related peptides on aldosterone secretion by adrenal glomerulosa cells: Critical role of the intramolecular disulphide bond Biochemical and Biophysical Research Communications. 122: 171-174. PMID 6331441 DOI: 10.1016/0006-291X(84)90455-8  0.374
1984 Schiffrin EL, Gutkowska J, Genest J. Effect of angiotensin II and deoxycorticosterone infusion on vascular angiotensin II receptors in rats. The American Journal of Physiology. 246: H608-14. PMID 6326599 DOI: 10.1152/Ajpheart.1984.246.4.H608  0.4
1984 Schiffrin EL, Thomé FS, Genest J. Vascular angiotensin II receptors in renal and DOCA-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979). 5: V16-21. PMID 6317555 DOI: 10.1161/01.HYP.5.6_Pt_3.V16  0.335
1984 Genest J, Cantin M, Garcia R, Thibault G, Gutkowska J, Schiffrin E, Kuchel O, Hamet P. Extrarenal angiotensin-forming enzymes. Clinical and Experimental Hypertension. Part a, Theory and Practice. 5: 1065-80. PMID 6315265 DOI: 10.3109/10641968309048842  0.366
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