Stephanie M. Reeve, Ph.D. - Publications

Affiliations: 
St. Jude Children’s Research Hospital, USA 
Area:
Drug Discovery, Antibiotic Resistance

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Phelps GA, Cheramie MN, Fernando DM, Selchow P, Meyer CJ, Waidyarachchi SL, Dharuman S, Liu J, Meuli M, Molin MD, Killam BY, Murphy PA, Reeve SM, Wilt LA, Anderson SM, et al. Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in abscessus. Proceedings of the National Academy of Sciences of the United States of America. 121: e2314101120. PMID 38165935 DOI: 10.1073/pnas.2314101120  0.505
2022 Leshchiner D, Rosconi F, Sundaresh B, Rudmann E, Ramirez LMN, Nishimoto AT, Wood SJ, Jana B, Buján N, Li K, Gao J, Frank M, Reeve SM, Lee RE, Rock CO, et al. A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance. Nature Communications. 13: 3165. PMID 35672367 DOI: 10.1038/s41467-022-30967-4  0.507
2022 Dharuman S, Wallace MJ, Reeve SM, Bulitta JB, Lee RE. Synthesis and Structure-Activity Relationship of Thioacetamide-Triazoles against . Molecules (Basel, Switzerland). 27. PMID 35268619 DOI: 10.3390/molecules27051518  0.471
2022 Wang S, Reeve SM, Holt GT, Ojewole AA, Frenkel MS, Gainza P, Keshipeddy S, Fowler VG, Wright DL, Donald BR. Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus. Plos Computational Biology. 18: e1009855. PMID 35143481 DOI: 10.1371/journal.pcbi.1009855  0.761
2021 Sharma S, Rao R, Reeve SM, Phelps GA, Bharatham N, Katagihallimath N, Ramachandran V, Raveendran S, Sarma M, Nath A, Thomas T, Manickam D, Nagaraj S, Balasubramanian V, Lee RE, et al. Azaindole Based Potentiator of Antibiotics against Gram-Negative Bacteria. Acs Infectious Diseases. PMID 34699190 DOI: 10.1021/acsinfecdis.1c00171  0.492
2021 Lang Y, Shah NR, Tao X, Reeve SM, Zhou J, Moya B, Sayed ARM, Dharuman S, Oyer JL, Copik AJ, Fleischer BA, Shin E, Werkman C, Basso KB, Deveson Lucas D, et al. Combating multidrug-resistant bacteria by integrating a novel target site penetration and receptor binding assay platform into translational modeling. Clinical Pharmacology and Therapeutics. PMID 33576025 DOI: 10.1002/cpt.2205  0.467
2021 Dharuman S, Wilt LA, Liu J, Reeve SM, Thompson CW, Elmore JM, Shcherbakov D, Lee RB, Böttger EC, Lee RE. Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins. The Journal of Antibiotics. PMID 33504919 DOI: 10.1038/s41429-021-00408-3  0.423
2020 Kim TH, Tao X, Moya B, Jiao Y, Basso KB, Zhou J, Lang Y, Sutaria DS, Zavascki AP, Barth AL, Reeve SM, Schweizer HP, Deveson Lucas D, Boyce JD, Bonomo RA, et al. Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant and . Mbio. 11. PMID 32047131 DOI: 10.1128/Mbio.03189-19  0.529
2019 Wallace MJ, Dharuman S, Fernando D, Reeve SM, Gee C, Yao J, Griffith E, Phelps G, Wright WC, Elmore J, Lee RB, Chen T, Lee RE. Discovery and characterization of the antimetabolite action of thioacetamide-linked 1,2,3-triazoles as disruptors of cysteine biosynthesis in Gram-negative bacteria. Acs Infectious Diseases. PMID 31887254 DOI: 10.1021/Acsinfecdis.9B00406  0.759
2019 Reeve SM, Si D, Krucinska J, Yan Y, Viswanathan K, Wang S, Holt GT, Frenkel MS, Ojewole A, Estrada A, Agabiti SS, Alverson JB, Gibson ND, Priestly ND, Wiemer AJ, et al. Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus. Acs Infectious Diseases. PMID 31565920 DOI: 10.1021/Acsinfecdis.9B00222  0.773
2019 Lombardo MN, G-Dayanandan N, Keshipeddy S, Zhou W, Si D, Reeve SM, Alverson J, Barney P, Walker L, Hoody J, Priestley N, Obach RS, Wright DL. Structure guided in-vitro to in-vivo pharmacokinetic optimization of propargyl-linked antifolates. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31201212 DOI: 10.1124/Dmd.119.086504  0.659
2017 Ojewole A, Lowegard A, Gainza P, Reeve SM, Georgiev I, Anderson AC, Donald BR. OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design. Methods in Molecular Biology (Clifton, N.J.). 1529: 291-306. PMID 27914058 DOI: 10.1007/978-1-4939-6637-0_15  0.763
2016 Reeve SM, Scocchera EW, G-Dayanadan N, Keshipeddy S, Krucinska J, Hajian B, Ferreira J, Nailor M, Aeschlimann J, Wright DL, Anderson AC. MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates. Cell Chemical Biology. PMID 27939900 DOI: 10.1016/J.Chembiol.2016.11.007  0.759
2016 Hajian B, Scocchera E, Keshipeddy S, G-Dayanandan N, Shoen C, Krucinska J, Reeve S, Cynamon M, Anderson AC, Wright DL. Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Plos One. 11: e0161740. PMID 27580226 DOI: 10.1371/Journal.Pone.0161740  0.722
2016 Scocchera E, Reeve SM, Keshipeddy S, Lombardo MN, Hajian B, Sochia AE, Alverson JB, Priestley ND, Anderson AC, Wright DL. Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens. Acs Medicinal Chemistry Letters. 7: 692-6. PMID 27437079 DOI: 10.1021/Acsmedchemlett.6B00120  0.689
2016 Reeve SM, Scocchera E, Ferreira J, G-Dayanandan N, Keshipeddy S, Wright DL, Anderson AC. Charged propargyl-linked antifolates reveal mechanisms of antifolate resistance and inhibit trimethoprim-resistant MRSA strains possessing clinically relevant mutations. Journal of Medicinal Chemistry. PMID 27308944 DOI: 10.1021/Acs.Jmedchem.6B00688  0.769
2015 Reeve SM, Lombardo MN, Anderson AC. Understanding the structural mechanisms of antibiotic resistance sets the platform for new discovery. Future Microbiology. PMID 26516790 DOI: 10.2217/Fmb.15.78  0.72
2015 Keshipeddy S, Reeve SM, Anderson AC, Wright DL. Non-racemic Antifolates Stereo-selectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus. Journal of the American Chemical Society. PMID 26098608 DOI: 10.1021/Jacs.5B01442  0.775
2015 Reeve SM, Gainza P, Frey KM, Georgiev I, Donald BR, Anderson AC. Protein design algorithms predict viable resistance to an experimental antifolate. Proceedings of the National Academy of Sciences of the United States of America. 112: 749-54. PMID 25552560 DOI: 10.1073/Pnas.1411548112  0.761
2011 Kelliher MT, Reeve SM, Agne ID, Southern CA. Single Molecule Fluorescence Studies of Antibody Structure Biophysical Journal. 100: 376a. DOI: 10.1016/J.Bpj.2010.12.2241  0.663
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