| Year |
Citation |
Score |
| 2023 |
Allen JP, Garber KB, Perszyk R, Khayat CT, Kell SA, Kaneko M, Quindipan C, Saitta S, Ladda RL, Hewson S, Inbar-Feigenberg M, Prasad C, Prasad AN, Olewiler L, Mu W, ... ... Yuan H, et al. Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants. Human Molecular Genetics. PMID 37944084 DOI: 10.1093/hmg/ddad188 |
0.812 |
|
| 2023 |
XiangWei W, Perszyk RE, Liu N, Xu Y, Bhattacharya S, Shaulsky GH, Smith-Hicks C, Fatemi A, Fry AE, Chandler K, Wang T, Vogt J, Cohen JS, Paciorkowski AR, Poduri A, ... ... Yuan H, et al. Clinical and functional consequences of GRIA variants in patients with neurological diseases. Cellular and Molecular Life Sciences : Cmls. 80: 345. PMID 37921875 DOI: 10.1007/s00018-023-04991-6 |
0.854 |
|
| 2023 |
Camp CR, Vlachos A, Klöckner C, Krey I, Banke TG, Shariatzadeh N, Ruggiero SM, Galer P, Park KL, Caccavano A, Kimmel S, Yuan X, Yuan H, Helbig I, Benke TA, et al. Loss of Grin2a causes a transient delay in the electrophysiological maturation of hippocampal parvalbumin interneurons. Communications Biology. 6: 952. PMID 37723282 DOI: 10.1038/s42003-023-05298-9 |
0.824 |
|
| 2023 |
Song R, Zhang J, Perszyk RE, Camp CR, Tang W, Kannan V, Li J, Xu Y, Chen J, Li Y, Liang SH, Traynelis SF, Yuan H. Differential responses of disease-related GRIN variants located in pore-forming M2 domain of N-methyl-D-aspartate receptor to FDA-approved inhibitors. Journal of Neurochemistry. PMID 37649269 DOI: 10.1111/jnc.15942 |
0.853 |
|
| 2023 |
Liu N, Li J, Gao K, Perszyk RE, Zhang J, Wang J, Wu Y, Jenkins A, Yuan H, Traynelis SF, Jiang Y. De novo CLPTM1 variants with reduced GABA R current response in patients with epilepsy. Epilepsia. PMID 37577761 DOI: 10.1111/epi.17746 |
0.751 |
|
| 2023 |
D'Erasmo MP, Akins NS, Ma P, Jing Y, Swanger SA, Sharma SK, Bartsch PW, Menaldino DS, Arcoria PJ, Bui TT, Pons-Bennaceur A, Le P, Allen JP, Ullman EZ, Nocilla KA, ... ... Yuan H, et al. Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the -Methyl-d-aspartate Receptor. Acs Chemical Neuroscience. PMID 37566734 DOI: 10.1021/acschemneuro.3c00181 |
0.845 |
|
| 2023 |
Hanson JE, Yuan H, Perszyk RE, Banke TG, Xing H, Tsai MC, Menniti FS, Traynelis SF. Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37369776 DOI: 10.1038/s41386-023-01614-3 |
0.861 |
|
| 2023 |
Myers SJ, Yuan H, Perszyk RE, Zhang J, Kim S, Nocilla KA, Allen JP, Bain JM, Lemke JR, Lal D, Benke TA, Traynelis SF. Classification of missense variants in the N-methyl-D-aspartate receptor GRIN gene family as gain- or loss-of-function. Human Molecular Genetics. PMID 37369021 DOI: 10.1093/hmg/ddad104 |
0.834 |
|
| 2023 |
Xie L, McDaniel MJ, Perszyk RE, Kim S, Cappuccio G, Shapiro KA, Muñoz-Cabello B, Sanchez-Lara PA, Grand K, Zhang J, Nocilla KA, Sheikh R, Armengol L, Romano R, Pierson TM, ... Yuan H, et al. Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening. Cellular and Molecular Life Sciences : Cmls. 80: 110. PMID 37000222 DOI: 10.1007/s00018-023-04705-y |
0.83 |
|
| 2023 |
Tang W, Beckley JT, Zhang J, Song R, Xu Y, Kim S, Quirk MC, Robichaud AJ, Diaz ES, Myers SJ, Doherty JJ, Ackley MA, Traynelis SF, Yuan H. Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions. Cellular and Molecular Life Sciences : Cmls. 80: 42. PMID 36645496 DOI: 10.1007/s00018-022-04667-7 |
0.641 |
|
| 2022 |
Han W, Yuan H, Allen JP, Kim S, Shaulsky GH, Perszyk RE, Traynelis SF, Myers SJ. . The Journal of Pharmacology and Experimental Therapeutics. PMID 35110392 DOI: 10.1124/jpet.121.001000 |
0.86 |
|
| 2021 |
Hansen KB, Wollmuth LP, Bowie D, Furukawa H, Menniti FS, Sobolevsky AI, Swanson GT, Swanger SA, Greger IH, Nakagawa T, McBain CJ, Jayaraman V, Low CM, Dell'Acqua ML, Diamond JS, ... ... Yuan H, et al. Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels. Pharmacological Reviews. 73: 298-487. PMID 34753794 DOI: 10.1124/pharmrev.120.000131 |
0.849 |
|
| 2021 |
Benke TA, Park K, Krey I, Camp CR, Song R, Ramsey AJ, Yuan H, Traynelis SF, Lemke J. Clinical and therapeutic significance of genetic variation in the GRIN gene family encoding NMDARs. Neuropharmacology. 108805. PMID 34560056 DOI: 10.1016/j.neuropharm.2021.108805 |
0.799 |
|
| 2021 |
Zhang J, Tang W, Bhatia NK, Xu Y, Paudyal N, Liu D, Kim S, Song R, XiangWei W, Shaulsky G, Myers SJ, Dobyns W, Jayaraman V, Traynelis SF, Yuan H, et al. A Variant Associated With Myoclonus and Developmental Delay: From Molecular Mechanism to Rescue Pharmacology. Frontiers in Genetics. 12: 694312. PMID 34413877 DOI: 10.3389/fgene.2021.694312 |
0.671 |
|
| 2021 |
Xu Y, Song R, Chen W, Strong K, Shrey D, Gedela S, Traynelis SF, Zhang G, Yuan H. Recurrent seizure-related GRIN1 variant: Molecular mechanism and targeted therapy. Annals of Clinical and Translational Neurology. PMID 34227748 DOI: 10.1002/acn3.51406 |
0.823 |
|
| 2021 |
Perszyk RE, Zheng Z, Banke TG, Zhang J, Xie L, McDaniel MJ, Katzman BM, Pelly SC, Yuan H, Liotta DC, Traynelis SF. . Molecular Pharmacology. PMID 33688039 DOI: 10.1124/molpharm.120.000218 |
0.863 |
|
| 2020 |
Tang W, Liu D, Traynelis SF, Yuan H. Positive allosteric modulators that target NMDA receptors rectify loss-of-function GRIN variants associated with neurological and neuropsychiatric disorders. Neuropharmacology. 108247. PMID 32712275 DOI: 10.1016/J.Neuropharm.2020.108247 |
0.734 |
|
| 2020 |
Amador A, Bostick CD, Olson H, Peters J, Camp CR, Krizay D, Chen W, Han W, Tang W, Kanber A, Kim S, Teoh J, Sah M, Petri S, Paek H, ... ... Yuan H, et al. Modelling and treating GRIN2A developmental and epileptic encephalopathy in mice. Brain : a Journal of Neurology. PMID 32577763 DOI: 10.1093/Brain/Awaa147 |
0.834 |
|
| 2020 |
Perszyk RE, Myers SJ, Yuan H, Gibb AJ, Furukawa H, Sobolevsky AI, Traynelis SF. Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif. The Journal of Physiology. PMID 32468591 DOI: 10.1113/Jp278086 |
0.859 |
|
| 2020 |
Zhu Z, Yi F, Epplin MP, Liu D, Summer SL, Mizu R, Shaulsky G, XiangWei W, Tang W, Burger PB, Menaldino DS, Myers SJ, Liotta DC, Hansen KB, Yuan H, et al. Negative allosteric modulation of GluN1/GluN3 NMDA receptors. Neuropharmacology. 108117. PMID 32389749 DOI: 10.1016/J.Neuropharm.2020.108117 |
0.831 |
|
| 2020 |
Piard J, Béreau M, XiangWei W, Wirth T, Amsallem D, Buisson L, Richard P, Liu N, Xu Y, Myers SJ, Traynelis SF, Chelly J, Anheim M, Raynaud M, Maldergem LV, ... Yuan H, et al. The GRIA3 c.2477G > A Variant Causes an Exaggerated Startle Reflex, Chorea, and Multifocal Myoclonus. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32369665 DOI: 10.1002/Mds.28058 |
0.604 |
|
| 2020 |
Perszyk RE, Swanger SA, Shelley C, Khatri A, Fernandez-Cuervo G, Epplin MP, Zhang J, Le P, Bülow P, Garnier-Amblard E, Gangireddy PKR, Bassell GJ, Yuan H, Menaldino DS, Liotta DC, et al. Biased modulators of NMDA receptors control channel opening and ion selectivity. Nature Chemical Biology. PMID 31959964 DOI: 10.1038/S41589-019-0449-5 |
0.826 |
|
| 2019 |
Camp CR, Yuan H. GRIN2D/GluN2D NMDA receptor: Unique features and its contribution to pediatric developmental and epileptic encephalopathy. European Journal of Paediatric Neurology : Ejpn : Official Journal of the European Paediatric Neurology Society. PMID 31918992 DOI: 10.1016/J.Ejpn.2019.12.007 |
0.849 |
|
| 2019 |
Myers SJ, Yuan H, Kang JQ, Tan FCK, Traynelis SF, Low CM. Distinct roles of and variants in neurological conditions. F1000research. 8. PMID 31807283 DOI: 10.12688/F1000Research.18949.1 |
0.643 |
|
| 2019 |
XiangWei W, Kannan V, Xu Y, Kosobucki GJ, Schulien AJ, Kusumoto H, Moufawad El Achkar C, Bhattacharya S, Lesca G, Nguyen S, Helbig KL, Cuisset JM, Fenger CD, Marjanovic D, Schuler E, ... ... Yuan H, et al. Heterogeneous clinical and functional features of GRIN2D-related developmental and epileptic encephalopathy. Brain : a Journal of Neurology. PMID 31504254 DOI: 10.1093/Brain/Awz232 |
0.87 |
|
| 2019 |
Li J, Zhang J, Tang W, Mizu RK, Kusumoto H, XiangWei W, Xu Y, Chen W, Amin JB, Perozo E, Hu C, Kannan V, Keller SR, Wilcox WR, Lemke JR, ... ... Yuan H, et al. De Novo GRIN Variants in NMDA Receptor M2 Channel Pore-Forming Loop Are Associated with Neurological Diseases. Human Mutation. PMID 31429998 DOI: 10.1002/Humu.23895 |
0.85 |
|
| 2019 |
Fu H, Tang W, Chen Z, Belov VV, Zhang G, Shao T, Zhang X, Yu Q, Rong J, Deng X, Han W, Myers S, Giffenig P, Wang L, Josephson L, ... ... Yuan H, et al. Synthesis and Preliminary Evaluations of a Triazole-cored Antagonist ([18F]N2B-0518) as PET Imaging Probe for GluN2B Subunit in the Brain. Acs Chemical Neuroscience. PMID 30698943 DOI: 10.1021/Acschemneuro.8B00591 |
0.568 |
|
| 2019 |
Regan MC, Zhu Z, Yuan H, Myers SJ, Menaldino DS, Tahirovic YA, Liotta DC, Traynelis SF, Furukawa H. Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors. Nature Communications. 10: 321. PMID 30659174 DOI: 10.2210/Pdb6E7S/Pdb |
0.656 |
|
| 2018 |
Wells G, Yuan H, McDaniel MJ, Kusumoto H, Snyder JP, Liotta DC, Traynelis SF. The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening. Proteins. PMID 30168177 DOI: 10.1002/Prot.25595 |
0.844 |
|
| 2018 |
Bhattacharya S, Khatri A, Swanger SA, DiRaddo JO, Yi F, Hansen KB, Yuan H, Traynelis SF. Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells. Neuron. 99: 315-328.e5. PMID 30056832 DOI: 10.1016/J.Neuron.2018.06.010 |
0.849 |
|
| 2018 |
XiangWei W, Jiang Y, Yuan H. Mutations and Rare Variants Occurring in NMDA Receptors. Current Opinion in Physiology. 2: 27-35. PMID 29756080 DOI: 10.1016/J.Cophys.2017.12.013 |
0.465 |
|
| 2018 |
Fernández-Marmiesse A, Kusumoto H, Rekarte S, Roca I, Zhang J, Myers SJ, Traynelis SF, Couce ML, Gutierrez-Solana L, Yuan H. A novel missense mutation in GRIN2A causes a nonepileptic neurodevelopmental disorder. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29644724 DOI: 10.1002/Mds.27315 |
0.675 |
|
| 2018 |
Fry AE, Fawcett KA, Zelnik N, Yuan H, Thompson BAN, Shemer-Meiri L, Cushion TD, Mugalaasi H, Sims D, Stoodley N, Chung SK, Rees MI, Patel CV, Brueton LA, Layet V, et al. De novo mutations in GRIN1 cause extensive bilateral polymicrogyria. Brain : a Journal of Neurology. PMID 29365063 DOI: 10.1093/Brain/Awx358 |
0.807 |
|
| 2017 |
Hu C, Chen W, Myers SJ, Yuan H, Traynelis SF. Corrigendum to "Human GRIN2B variants in neurodevelopmental disorders" [J Pharmacol Sci 132 (2) 115-121]. Journal of Pharmacological Sciences. PMID 28434657 DOI: 10.1016/J.Jphs.2017.04.001 |
0.503 |
|
| 2017 |
Platzer K, Yuan H, Schütz H, Winschel A, Chen W, Hu C, Kusumoto H, Heyne HO, Helbig KL, Tang S, Willing MC, Tinkle BT, Adams DJ, Depienne C, Keren B, et al. GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects. Journal of Medical Genetics. PMID 28377535 DOI: 10.1136/Jmedgenet-2016-104509 |
0.536 |
|
| 2017 |
Liu S, Zhou L, Yuan H, Vieira M, Sanz-Clemente A, Badger JD, Lu W, Traynelis SF, Roche KW. A rare variant identified within the GluN2B C-terminus in a patient with autism affects NMDA receptor surface expression and spine density. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28283559 DOI: 10.1523/Jneurosci.0827-16.2017 |
0.709 |
|
| 2017 |
Chen W, Shieh C, Swanger SA, Tankovic A, Au M, McGuire M, Tagliati M, Graham JM, Madan-Khetarpal S, Traynelis SF, Yuan H, Pierson TM. GRIN1 mutation associated with intellectual disability alters NMDA receptor trafficking and function. Journal of Human Genetics. PMID 28228639 DOI: 10.1038/Jhg.2017.19 |
0.82 |
|
| 2017 |
Gao K, Tankovic A, Zhang Y, Kusumoto H, Zhang J, Chen W, XiangWei W, Shaulsky GH, Hu C, Traynelis SF, Yuan H, Jiang Y. A de novo loss-of-function GRIN2A mutation associated with childhood focal epilepsy and acquired epileptic aphasia. Plos One. 12: e0170818. PMID 28182669 DOI: 10.1371/Journal.Pone.0170818 |
0.625 |
|
| 2017 |
Chen W, Tankovic A, Burger PB, Kusumoto H, Traynelis SF, Yuan H. Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy. Molecular Pharmacology. PMID 28126851 DOI: 10.1124/Mol.116.106781 |
0.73 |
|
| 2017 |
Ogden KK, Chen W, Swanger SA, McDaniel MJ, Fan LZ, Hu C, Tankovic A, Kusumoto H, Kosobucki GJ, Schulien AJ, Su Z, Pecha J, Bhattacharya S, Petrovski S, Cohen AE, ... ... Yuan H, et al. Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology. Plos Genetics. 13: e1006536. PMID 28095420 DOI: 10.1371/Journal.Pgen.1006536 |
0.84 |
|
| 2016 |
Swanger SA, Chen W, Wells G, Burger PB, Tankovic A, Bhattacharya S, Strong KL, Hu C, Kusumoto H, Zhang J, Adams DR, Millichap JJ, Petrovski S, Traynelis SF, Yuan H. Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains. American Journal of Human Genetics. PMID 27839871 DOI: 10.1016/J.Ajhg.2016.10.002 |
0.833 |
|
| 2016 |
Hu C, Chen W, Myers SJ, Yuan H, Traynelis SF. Human GRIN2B variants in neurodevelopmental disorders. Journal of Pharmacological Sciences. PMID 27818011 DOI: 10.1016/J.Jphs.2016.10.002 |
0.583 |
|
| 2016 |
Li D, Yuan H, Ortiz-Gonzalez XR, Marsh ED, Tian L, McCormick EM, Kosobucki GJ, Chen W, Schulien AJ, Chiavacci R, Tankovic A, Naase C, Brueckner F, von Stülpnagel-Steinbeis C, Hu C, et al. GRIN2D Recurrent De Novo Dominant Mutation Causes a Severe Epileptic Encephalopathy Treatable with NMDA Receptor Channel Blockers. American Journal of Human Genetics. PMID 27616483 DOI: 10.1016/J.Ajhg.2016.07.013 |
0.699 |
|
| 2015 |
Chen W, Yuan H. GRIN1 Mutations in Early-Onset Epileptic Encephalopathy. Pediatric Neurology Briefs. 29: 44. PMID 26933583 DOI: 10.15844/Pedneurbriefs-29-6-3 |
0.487 |
|
| 2015 |
Katzman BM, Perszyk RE, Yuan H, Tahirovic YA, Sotimehin AE, Traynelis SF, Liotta DC. A novel class of negative allosteric modulators of NMDA receptor function. Bioorganic & Medicinal Chemistry Letters. 25: 5583-8. PMID 26525866 DOI: 10.1016/J.Bmcl.2015.10.046 |
0.865 |
|
| 2015 |
Yuan H, Low CM, Moody OA, Jenkins A, Traynelis SF. Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases. Molecular Pharmacology. 88: 203-17. PMID 25904555 DOI: 10.1124/Mol.115.097998 |
0.691 |
|
| 2015 |
Yuan H, Myers SJ, Wells G, Nicholson KL, Swanger SA, Lyuboslavsky P, Tahirovic YA, Menaldino DS, Ganesh T, Wilson LJ, Liotta DC, Snyder JP, Traynelis SF. Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects. Neuron. 85: 1305-18. PMID 25728572 DOI: 10.1016/J.Neuron.2015.02.008 |
0.783 |
|
| 2014 |
Adams DR, Yuan H, Holyoak T, Arajs KH, Hakimi P, Markello TC, Wolfe LA, Vilboux T, Burton BK, Fajardo KF, Grahame G, Holloman C, Sincan M, Smith AC, Wells GA, et al. Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity. Molecular Genetics and Metabolism. 113: 161-70. PMID 24863970 DOI: 10.1016/J.Ymgme.2014.04.001 |
0.615 |
|
| 2014 |
Pierson TM, Yuan H, Marsh ED, Fuentes-Fajardo K, Adams DR, Markello T, Golas G, Simeonov DR, Holloman C, Tankovic A, Karamchandani MM, Schreiber JM, Mullikin JC, Tifft CJ, et al. GRIN2A mutation and early-onset epileptic encephalopathy: personalized therapy with memantine. Annals of Clinical and Translational Neurology. 1: 190-198. PMID 24839611 DOI: 10.1002/Acn3.39 |
0.656 |
|
| 2014 |
Hansen KB, Ogden KK, Yuan H, Traynelis SF. Distinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors. Neuron. 81: 1084-96. PMID 24607230 DOI: 10.1016/J.Neuron.2014.01.035 |
0.873 |
|
| 2014 |
Yuan H, Hansen KB, Zhang J, Pierson TM, Markello TC, Fajardo KV, Holloman CM, Golas G, Adams DR, Boerkoel CF, Gahl WA, Traynelis SF. Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy. Nature Communications. 5: 3251. PMID 24504326 DOI: 10.1038/Ncomms4251 |
0.771 |
|
| 2014 |
Ogden KK, Yuan H, Hansen KB, Zhang J, Gibb AJ, Traynelis SF. A Human Mutation in the M4 Helix of GluN2A Accelerates Forward Gating Transitions in NMDA Receptors Biophysical Journal. 106: 150a. DOI: 10.1016/J.Bpj.2013.11.863 |
0.854 |
|
| 2012 |
Burger PB, Yuan H, Karakas E, Geballe M, Furukawa H, Liotta DC, Snyder JP, Traynelis SF. Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators. Molecular Pharmacology. 82: 344-59. PMID 22596351 DOI: 10.1124/Mol.112.078568 |
0.625 |
|
| 2011 |
Acker TM, Yuan H, Hansen KB, Vance KM, Ogden KK, Jensen HS, Burger PB, Mullasseril P, Snyder JP, Liotta DC, Traynelis SF. Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators. Molecular Pharmacology. 80: 782-95. PMID 21807990 DOI: 10.1124/Mol.111.073239 |
0.862 |
|
| 2010 |
Mullasseril P, Hansen KB, Vance KM, Ogden KK, Yuan H, Kurtkaya NL, Santangelo R, Orr AG, Le P, Vellano KM, Liotta DC, Traynelis SF. A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. Nature Communications. 1: 90. PMID 20981015 DOI: 10.1038/Ncomms1085 |
0.874 |
|
| 2010 |
Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Glutamate receptor ion channels: structure, regulation, and function. Pharmacological Reviews. 62: 405-96. PMID 20716669 DOI: 10.1124/Pr.109.002451 |
0.867 |
|
| 2010 |
Hansen KB, Mullasseril P, Dawit S, Kurtkaya NL, Yuan H, Vance KM, Orr AG, Kvist T, Ogden KK, Le P, Vellano KM, Lewis I, Kurtkaya S, Du Y, Qui M, et al. Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists. The Journal of Pharmacology and Experimental Therapeutics. 333: 650-62. PMID 20197375 DOI: 10.1124/Jpet.110.166256 |
0.864 |
|
| 2010 |
Nagatomo K, Suga S, Shibasaki K, Watanabe N, Kodama S, Yuan H, Inagaki N, Yamamoto Y, Tominaga M, Yamada K. The expression of the dopamine receptors in neurons and astrocytes of the substantia nigra pars reticulata by single-cell real time RT-PCR Neuroscience Research. 68: e126. DOI: 10.1016/J.Neures.2010.07.2127 |
0.359 |
|
| 2010 |
Dravid SM, Yuan H, Traynelis SF. AMPA Receptors: Molecular Biology and Pharmacology Encyclopedia of Neuroscience. 311-318. DOI: 10.1016/B978-008045046-9.01221-3 |
0.793 |
|
| 2009 |
Yuan H, Hansen KB, Vance KM, Ogden KK, Traynelis SF. Control of NMDA receptor function by the NR2 subunit amino-terminal domain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12045-58. PMID 19793963 DOI: 10.1523/Jneurosci.1365-09.2009 |
0.867 |
|
| 2009 |
Mosley CA, Myers SJ, Murray EE, Santangelo R, Tahirovic YA, Kurtkaya N, Mullasseril P, Yuan H, Lyuboslavsky P, Le P, Wilson LJ, Yepes M, Dingledine R, Traynelis SF, Liotta DC. Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors. Bioorganic & Medicinal Chemistry. 17: 6463-80. PMID 19648014 DOI: 10.1016/J.Bmc.2009.05.085 |
0.79 |
|
| 2009 |
Yuan H, Vance KM, Junge CE, Geballe MT, Snyder JP, Hepler JR, Yepes M, Low CM, Traynelis SF. The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 284: 12862-73. PMID 19240037 DOI: 10.1074/Jbc.M805123200 |
0.864 |
|
| 2008 |
Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, et al. Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. Journal of Medicinal Chemistry. 51: 5506-21. PMID 18800760 DOI: 10.1021/Jm8002153 |
0.776 |
|
| 2008 |
Mannaioni G, Orr AG, Hamill CE, Yuan H, Pedone KH, McCoy KL, Berlinguer Palmini R, Junge CE, Lee CJ, Yepes M, Hepler JR, Traynelis SF. Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1. The Journal of Biological Chemistry. 283: 20600-11. PMID 18474593 DOI: 10.1074/Jbc.M803015200 |
0.815 |
|
| 2008 |
Yuan H, Geballe MT, Hansen KB, Traynelis SF. Structure and function of the NMDA receptor Structural and Functional Organization of the Synapse. 289-316. DOI: 10.1007/978-0-387-77232-5_11 |
0.775 |
|
| 2007 |
Erreger K, Geballe MT, Kristensen A, Chen PE, Hansen KB, Lee CJ, Yuan H, Le P, Lyuboslavsky PN, Micale N, Jørgensen L, Clausen RP, Wyllie DJ, Snyder JP, Traynelis SF. Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors. Molecular Pharmacology. 72: 907-20. PMID 17622578 DOI: 10.1124/Mol.107.037333 |
0.866 |
|
| 2007 |
Hamill CE, Caudle WM, Richardson JR, Yuan H, Pennell KD, Greene JG, Miller GW, Traynelis SF. Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1. Molecular Pharmacology. 72: 653-64. PMID 17596374 DOI: 10.1124/Mol.107.038158 |
0.806 |
|
| 2007 |
Hansen KB, Yuan H, Traynelis SF. Structural aspects of AMPA receptor activation, desensitization and deactivation. Current Opinion in Neurobiology. 17: 281-8. PMID 17419047 DOI: 10.1016/J.Conb.2007.03.014 |
0.796 |
|
| 2007 |
Lee CJ, Mannaioni G, Yuan H, Woo DH, Gingrich MB, Traynelis SF. Astrocytic control of synaptic NMDA receptors. The Journal of Physiology. 581: 1057-81. PMID 17412766 DOI: 10.1113/Jphysiol.2007.130377 |
0.759 |
|
| 2007 |
Dravid SM, Erreger K, Yuan H, Nicholson K, Le P, Lyuboslavsky P, Almonte A, Murray E, Mosely C, Barber J, French A, Balster R, Murray TF, Traynelis SF. Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block. The Journal of Physiology. 581: 107-28. PMID 17303642 DOI: 10.1113/Jphysiol.2006.124958 |
0.835 |
|
| 2005 |
Yuan H, Erreger K, Dravid SM, Traynelis SF. Conserved structural and functional control of N-methyl-D-aspartate receptor gating by transmembrane domain M3. The Journal of Biological Chemistry. 280: 29708-16. PMID 15970596 DOI: 10.1074/Jbc.M414215200 |
0.866 |
|
| 2005 |
Chen PE, Geballe MT, Stansfeld PJ, Johnston AR, Yuan H, Jacob AL, Snyder JP, Traynelis SF, Wyllie DJ. Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling. Molecular Pharmacology. 67: 1470-84. PMID 15703381 DOI: 10.1124/Mol.104.008185 |
0.749 |
|
| 2004 |
Yuan H, Yamada K, Inagaki N. Glucose sensitivity in mouse substantia nigra pars reticulata neurons in vitro. Neuroscience Letters. 355: 173-6. PMID 14732459 DOI: 10.1016/J.Neulet.2003.10.068 |
0.327 |
|
| 2004 |
Yuan H, Yamada K, Inagaki N. Multiminute oscillations in mouse substantia nigra pars reticulata neurons in vitro. Neuroscience Letters. 355: 136-40. PMID 14729253 DOI: 10.1016/J.Neulet.2003.10.058 |
0.392 |
|
| 2001 |
Yamada K, Ji JJ, Yuan H, Miki T, Sato S, Horimoto N, Shimizu T, Seino S, Inagaki N. Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science. 292: 1543-1546. PMID 11375491 DOI: 10.1126/Science.1059829 |
0.358 |
|
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