Year |
Citation |
Score |
2021 |
Chu X, Li J, Qiao C, Wang J, Wang Y, Jiang XC, You H, Xiao X, Wang B. Long-term effect of human mini-dystrophin in transgenic mdx mice improves muscle physiological function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21628. PMID 33982338 DOI: 10.1096/fj.202100057RR |
0.334 |
|
2019 |
Jin Q, Qiao C, Li J, Li J, Xiao X. An engineered serum albumin-binding AAV9 capsid achieves improved liver transduction after intravenous delivery in mice. Gene Therapy. PMID 31819202 DOI: 10.1038/S41434-019-0107-2 |
0.371 |
|
2019 |
Jin Q, Qiao C, Li J, Xiao B, Li J, Xiao X. A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx mice. Skeletal Muscle. 9: 16. PMID 31133057 DOI: 10.1186/S13395-019-0197-Y |
0.365 |
|
2018 |
Yan H, Meng J, Zhang S, Zhuang H, Song Y, Xiao X, Wang DW, Jiang J. Pretreatment of rAAV-Mediated Expression of Myostatin Propeptide Lowers Type 2 Diabetes Incidence in C57BL/6 Mice on High-fat Diet. Human Gene Therapy. PMID 30526118 DOI: 10.1089/Hum.2018.140 |
0.304 |
|
2018 |
Bulaklak K, Xiao B, Qiao C, Li J, Patel T, Jin Q, Li J, Xiao X. MicroRNA-206 Downregulation Improves Therapeutic Gene Expression and Motor Function in mdx Mice. Molecular Therapy. Nucleic Acids. 12: 283-293. PMID 30195767 DOI: 10.1016/J.Omtn.2018.05.011 |
0.422 |
|
2018 |
Xiao W, Gao G, Ling C, Herzog RW, Xiao X, Samulski RJ. Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates. Nature Medicine. PMID 29867233 DOI: 10.1038/S41591-018-0062-2 |
0.456 |
|
2018 |
Tucker JD, Lu PJ, Xiao X, Lu QL. Overexpression of Mutant FKRP Restores Functional Glycosylation and Improves Dystrophic Phenotype in FKRP Mutant Mice. Molecular Therapy. Nucleic Acids. 11: 216-227. PMID 29858056 DOI: 10.1016/J.Omtn.2018.02.008 |
0.359 |
|
2018 |
Qiao C, Dai Y, Nikolova VD, Jin Q, Li J, Xiao B, Li J, Moy SS, Xiao X. Amelioration of Muscle and Nerve Pathology in LAMA2 Muscular Dystrophy by AAV9-Mini-Agrin. Molecular Therapy. Methods & Clinical Development. 9: 47-56. PMID 29766020 DOI: 10.1016/J.Omtm.2018.01.005 |
0.412 |
|
2018 |
Jin Q, Qiao C, Li J, Li J, Xiao X. Neonatal Systemic AAV-Mediated Gene Delivery of GDF11 Inhibits Skeletal Muscle Growth. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29503194 DOI: 10.1016/J.Ymthe.2018.01.016 |
0.379 |
|
2017 |
Sun J, Yuan Z, Abajas YL, Szollosi DE, Hu G, Hua B, Xiao X, Li C. A retrospective study of cytokine profiles changes in mice with FVIII inhibitor development after AAV mediated gene therapy in hemophilia A mouse model. Human Gene Therapy. PMID 28922951 DOI: 10.1089/Hum.2017.094 |
0.373 |
|
2017 |
Zheng H, Qiao C, Tang R, Li J, Bulaklak K, Huang Z, Zhao C, Dai Y, Li J, Xiao X. Follistatin N terminus differentially regulates muscle size and fat in vivo. Experimental & Molecular Medicine. 49: e377. PMID 28912572 DOI: 10.1038/Emm.2017.135 |
0.359 |
|
2017 |
Bulaklak K, Xiao X. Therapeutic advances in musculoskeletal AAV targeting approaches. Current Opinion in Pharmacology. 34: 56-63. PMID 28743034 DOI: 10.1016/J.Coph.2017.07.001 |
0.429 |
|
2017 |
Vannoy CH, Xiao W, Lu P, Xiao X, Lu QL. Efficacy of Gene Therapy Is Dependent on Disease Progression in Dystrophic Mice with Mutations in the FKRP Gene. Molecular Therapy. Methods & Clinical Development. 5: 31-42. PMID 28480302 DOI: 10.1016/J.Omtm.2017.02.002 |
0.429 |
|
2017 |
Yin C, Zhang T, Qu X, Zhang Y, Putatunda R, Xiao X, Li F, Xiao W, Zhao H, Dai S, Qin X, Mo X, Young WB, Khalili K, Hu W. In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28366764 DOI: 10.1016/J.Ymthe.2017.03.012 |
0.383 |
|
2017 |
Vannoy CH, Zhou H, Qiao C, Xiao X, Bang AG, Lu QL. Adeno-Associated Virus-Mediated Mini-Agrin Delivery Is Unable to Rescue Disease Phenotype in a Mouse Model of Limb Girdle Muscular Dystrophy Type 2I. The American Journal of Pathology. 187: 431-440. PMID 28107841 DOI: 10.1016/J.Ajpath.2016.09.024 |
0.359 |
|
2016 |
Jiang J, Shen G, Li J, Qiao C, Xiao B, Yan H, Wang DW, Xiao X. Adeno-associated virus-mediated expression of myostatin propeptide improves the growth of skeletal muscle and attenuates hyperglycemia in db/db mice. Gene Therapy. PMID 27983718 DOI: 10.1038/Gt.2016.85 |
0.379 |
|
2016 |
Li J, Komegay J, Qiao C, Zheng H, Li J, Tang R, Dai Y, Xiao X. 721. Long-Term (2-8 years) Body-Wide Expression of AAV9-Minidystrophin Gene in Golden Retriever Muscular Dystrophy Dogs After Regional Limb Vein Injection Molecular Therapy. 24: S284. DOI: 10.1016/S1525-0016(16)33529-8 |
0.442 |
|
2015 |
Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A. The Adeno-Associated Virus Genome Packaging Puzzle. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research. 9. PMID 26949410 DOI: 10.4172/1747-0862.1000175 |
0.538 |
|
2015 |
He B, Cruz-Topete D, Oakley RH, Xiao X, Cidlowski JA. Human Glucocorticoid Receptor β (hGRβ) Regulates Gluconeogenesis and Inflammation in Mouse Liver. Molecular and Cellular Biology. PMID 26711253 DOI: 10.1128/Mcb.00908-15 |
0.302 |
|
2015 |
Berns KI, Byrne BJ, Flotte TR, Gao G, Hauswirth WW, Herzog RW, Muzyczka N, VandenDriessche T, Xiao X, Zolotukhin S, Srivastava A. Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma? Human Gene Therapy. 26: 779-81. PMID 26690810 DOI: 10.1089/Hum.2015.29014.Kib |
0.627 |
|
2015 |
Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A. Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo. Journal of Virology. 89: 952-61. PMID 25355884 DOI: 10.1128/Jvi.02581-14 |
0.581 |
|
2015 |
Xiao B, Yuan Z, Yang L, Qiao C, Li J, Li J, Xiao X. 603. Novel DNA-Shuffled AAV Capsids Show Robust and Unique Gene Delivery and Expression Profiles in the CNS Via Intrathecal Injection Molecular Therapy. 23: S239-S240. DOI: 10.1016/S1525-0016(16)34212-5 |
0.397 |
|
2015 |
Qiao C, Dai Y, Nikolova V, Li J, Li J, Moy S, Xiao X. 507. AAV-Mini-Agrin for Laminin-alpha2 Deficient CMD Molecular Therapy. 23: S203. DOI: 10.1016/S1525-0016(16)34116-8 |
0.386 |
|
2015 |
Tremblay JP, Gérard C, Xiao X, Filali M, Coulombe Z, Arsenault M, Couet J, Li J, Drolet M, Chapdelaine P, Chikh A. 384. AAV9 -Frataxin Reduces the Symptoms and Prolongs the Life of Friedreich Ataxia Mouse Models Molecular Therapy. 23: S153. DOI: 10.1016/S1525-0016(16)33993-4 |
0.374 |
|
2015 |
Martin CB, Mayer C, Qiao C, Yuan Z, Yang L, Li J, Li J, Xiao X. 317. HH67.2, a Promising Novel Adeno-Associated Virus (AAV) Vector, Shows Improved Muscle Specificity and Infectivity Compared To AAV9 Molecular Therapy. 23: S128. DOI: 10.1016/S1525-0016(16)33926-0 |
0.453 |
|
2015 |
Xiao B, Zheng P, Yuan Z, Qiao C, Li J, Xiao X. 102. AAV9 Exclusively Targets the Juxtaglomerular Apparatus in the Adult Mouse Kidney After Intravenous Injection Molecular Therapy. 23: S43. DOI: 10.1016/S1525-0016(16)33707-8 |
0.323 |
|
2014 |
Gérard C, Xiao X, Filali M, Coulombe Z, Arsenault M, Couet J, Li J, Drolet MC, Chapdelaine P, Chikh A, Tremblay JP. An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse models. Molecular Therapy. Methods & Clinical Development. 1: 14044. PMID 26015982 DOI: 10.1038/Mtm.2014.44 |
0.393 |
|
2014 |
Qiao C, Wang CH, Zhao C, Lu P, Awano H, Xiao B, Li J, Yuan Z, Dai Y, Martin CB, Li J, Lu Q, Xiao X. Muscle and heart function restoration in a limb girdle muscular dystrophy 2I (LGMD2I) mouse model by systemic FKRP gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1890-9. PMID 25048216 DOI: 10.1038/Mt.2014.141 |
0.43 |
|
2014 |
Lenhart KC, Becherer AL, Li J, Xiao X, McNally EM, Mack CP, Taylor JM. GRAF1 promotes ferlin-dependent myoblast fusion. Developmental Biology. 393: 298-311. PMID 25019370 DOI: 10.1016/J.Ydbio.2014.06.025 |
0.331 |
|
2014 |
Vannoy CH, Xu L, Keramaris E, Lu P, Xiao X, Lu QL. Adeno-associated virus-mediated overexpression of LARGE rescues α-dystroglycan function in dystrophic mice with mutations in the fukutin-related protein. Human Gene Therapy Methods. 25: 187-96. PMID 24635668 DOI: 10.1089/Hgtb.2013.151 |
0.405 |
|
2014 |
Ma HI, Hueng DY, Shui HA, Han JM, Wang CH, Lai YH, Cheng SY, Xiao X, Chen MT, Yang YP. Intratumoral decorin gene delivery by AAV vector inhibits brain glioblastomas and prolongs survival of animals by inducing cell differentiation. International Journal of Molecular Sciences. 15: 4393-414. PMID 24625664 DOI: 10.3390/Ijms15034393 |
0.381 |
|
2014 |
Qiao C, Li C, Zhao C, Li J, Bian T, Grieger J, Li J, Samulski RJ, Xiao X. K137R mutation on adeno-associated viral capsids had minimal effect on enhancing gene delivery in vivo. Human Gene Therapy Methods. 25: 33-9. PMID 24116972 DOI: 10.1089/Hgtb.2013.176 |
0.46 |
|
2013 |
Xu L, Lu PJ, Wang CH, Keramaris E, Qiao C, Xiao B, Blake DJ, Xiao X, Lu QL. Adeno-associated virus 9 mediated FKRP gene therapy restores functional glycosylation of α-dystroglycan and improves muscle functions. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1832-40. PMID 23817215 DOI: 10.1038/Mt.2013.156 |
0.455 |
|
2013 |
Blaeser A, Keramaris E, Chan YM, Sparks S, Cowley D, Xiao X, Lu QL. Mouse models of fukutin-related protein mutations show a wide range of disease phenotypes. Human Genetics. 132: 923-34. PMID 23591631 DOI: 10.1007/S00439-013-1302-7 |
0.322 |
|
2013 |
Lee HH, O'Malley MJ, Friel NA, Payne KA, Qiao C, Xiao X, Chu CR. Persistence, localization, and external control of transgene expression after single injection of adeno-associated virus into injured joints. Human Gene Therapy. 24: 457-66. PMID 23496155 DOI: 10.1089/Hum.2012.118 |
0.339 |
|
2013 |
Yang L, Xiao X. Creation of a cardiotropic adeno-associated virus: the story of viral directed evolution. Virology Journal. 10: 50. PMID 23394344 DOI: 10.1186/1743-422X-10-50 |
0.438 |
|
2013 |
Tremblay JP, Xiao X, Aartsma-Rus A, Barbas C, Blau HM, Bogdanove AJ, Boycott K, Braun S, Breakefield XO, Bueren JA, Buschmann M, Byrne BJ, Calos M, Cathomen T, Chamberlain J, et al. Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 266-8. PMID 23369965 DOI: 10.1038/Mt.2013.4 |
0.699 |
|
2013 |
Qiao C, Yuan Z, Li J, Tang R, Li J, Xiao X. Single tyrosine mutation in AAV8 and AAV9 capsids is insufficient to enhance gene delivery to skeletal muscle and heart. Human Gene Therapy Methods. 23: 29-37. PMID 22428978 DOI: 10.1089/Hgtb.2011.229 |
0.462 |
|
2012 |
He B, Tang RH, Weisleder N, Xiao B, Yuan Z, Cai C, Zhu H, Lin P, Qiao C, Li J, Mayer C, Li J, Ma J, Xiao X. Enhancing muscle membrane repair by gene delivery of MG53 ameliorates muscular dystrophy and heart failure in δ-Sarcoglycan-deficient hamsters. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 727-35. PMID 22314291 DOI: 10.1038/Mt.2012.5 |
0.376 |
|
2012 |
Kornegay JN, Bogan JR, Bogan DJ, Childers MK, Li J, Nghiem P, Detwiler DA, Larsen CA, Grange RW, Bhavaraju-Sanka RK, Tou S, Keene BP, Howard JF, Wang J, Fan Z, ... Xiao X, et al. Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 85-108. PMID 22218699 DOI: 10.1007/S00335-011-9382-Y |
0.385 |
|
2012 |
Bowles DE, McPhee SW, Li C, Gray SJ, Samulski JJ, Camp AS, Li J, Wang B, Monahan PE, Rabinowitz JE, Grieger JC, Govindasamy L, Agbandje-McKenna M, Xiao X, Samulski RJ. Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 443-55. PMID 22068425 DOI: 10.1038/Mt.2011.237 |
0.696 |
|
2011 |
Qiao C, Koo T, Li J, Xiao X, Dickson JG. Gene therapy in skeletal muscle mediated by adeno-associated virus vectors Methods in Molecular Biology. 807: 119-140. PMID 22034028 DOI: 10.1007/978-1-61779-370-7_5 |
0.474 |
|
2011 |
Payne KA, Lee HH, Haleem AM, Martins C, Yuan Z, Qiao C, Xiao X, Chu CR. Single intra-articular injection of adeno-associated virus results in stable and controllable in vivo transgene expression in normal rat knees. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 19: 1058-65. PMID 21571082 DOI: 10.1016/J.Joca.2011.04.009 |
0.385 |
|
2011 |
Pichavant C, Aartsma-Rus A, Clemens PR, Davies KE, Dickson G, Takeda S, Wilton SD, Wolff JA, Wooddell CI, Xiao X, Tremblay JP. Current status of pharmaceutical and genetic therapeutic approaches to treat DMD. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 830-40. PMID 21468001 DOI: 10.1038/Mt.2011.59 |
0.43 |
|
2011 |
Lee HH, Haleem AM, Yao V, Li J, Xiao X, Chu CR. Release of bioactive adeno-associated virus from fibrin scaffolds: effects of fibrin glue concentrations. Tissue Engineering. Part A. 17: 1969-78. PMID 21449684 DOI: 10.1089/Ten.Tea.2010.0586 |
0.325 |
|
2011 |
Nguyen AT, Xiao B, Neppl RL, Kallin EM, Li J, Chen T, Wang DZ, Xiao X, Zhang Y. DOT1L regulates dystrophin expression and is critical for cardiac function. Genes & Development. 25: 263-74. PMID 21289070 DOI: 10.1101/Gad.2018511 |
0.327 |
|
2011 |
Wang CH, Chan YM, Tang RH, Xiao B, Lu P, Keramaris-Vrantsis E, Zheng H, Qiao C, Jiang J, Li J, Ma HI, Lu Q, Xiao X. Post-Natal knockdown of fukutin-related protein expression in muscle by long-termRNA interference induces dystrophic pathology [corrected]. The American Journal of Pathology. 178: 261-72. PMID 21224063 DOI: 10.1016/J.Ajpath.2010.11.020 |
0.464 |
|
2011 |
Yang L, Li J, Xiao X. Directed evolution of adeno-associated virus (AAV) as vector for muscle gene therapy. Methods in Molecular Biology (Clifton, N.J.). 709: 127-39. PMID 21194025 DOI: 10.1007/978-1-61737-982-6_8 |
0.47 |
|
2011 |
Yuan Z, Qiao C, Hu P, Li J, Xiao X. A versatile adeno-associated virus vector producer cell line method for scalable vector production of different serotypes. Human Gene Therapy. 22: 613-24. PMID 21186998 DOI: 10.1089/Hum.2010.241 |
0.372 |
|
2011 |
Wu B, Xiao B, Cloer C, Shaban M, Sali A, Lu P, Li J, Nagaraju K, Xiao X, Lu QL. One-year treatment of morpholino antisense oligomer improves skeletal and cardiac muscle functions in dystrophic mdx mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 576-83. PMID 21179007 DOI: 10.1038/Mt.2010.288 |
0.384 |
|
2011 |
Qiao C, Yuan Z, Li J, He B, Zheng H, Mayer C, Li J, Xiao X. Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver. Gene Therapy. 18: 403-10. PMID 21150938 DOI: 10.1038/Gt.2010.157 |
0.339 |
|
2011 |
Hoshijima M, Hayashi T, Jeon YE, Fu Z, Gu Y, Dalton ND, Ellisman MH, Xiao X, Powell FL, Ross J. Delta-sarcoglycan gene therapy halts progression of cardiac dysfunction, improves respiratory failure, and prolongs life in myopathic hamsters. Circulation. Heart Failure. 4: 89-97. PMID 21036890 DOI: 10.1161/Circheartfailure.110.957258 |
0.361 |
|
2010 |
Xiao X. Adeno-associated viral vectors found free in media Human Gene Therapy. 21: 1221-1222. PMID 20942751 DOI: 10.1089/Hum.2010.921 |
0.33 |
|
2010 |
Mendell JR, Campbell K, Rodino-Klapac L, Sahenk Z, Shilling C, Lewis S, Bowles D, Gray S, Li C, Galloway G, Malik V, Coley B, Clark KR, Li J, Xiao X, et al. Dystrophin immunity in Duchenne's muscular dystrophy. The New England Journal of Medicine. 363: 1429-37. PMID 20925545 DOI: 10.1056/Nejmoa1000228 |
0.681 |
|
2010 |
Koppanati BM, Li J, Reay DP, Wang B, Daood M, Zheng H, Xiao X, Watchko JF, Clemens PR. Improvement of the mdx mouse dystrophic phenotype by systemic in utero AAV8 delivery of a minidystrophin gene. Gene Therapy. 17: 1355-62. PMID 20535217 DOI: 10.1038/Gt.2010.84 |
0.426 |
|
2010 |
Kornegay JN, Li J, Bogan JR, Bogan DJ, Chen C, Zheng H, Wang B, Qiao C, Howard JF, Xiao X. Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1501-8. PMID 20517298 DOI: 10.1038/Mt.2010.94 |
0.432 |
|
2010 |
Qiao C, Zhang W, Yuan Z, Shin JH, Li J, Jayandharan GR, Zhong L, Srivastava A, Xiao X, Duan D. Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle. Human Gene Therapy. 21: 1343-8. PMID 20497037 DOI: 10.1089/Hum.2010.003 |
0.483 |
|
2010 |
Pichavant C, Chapdelaine P, Cerri DG, Dominique JC, Quenneville SP, Skuk D, Kornegay JN, Bizario JC, Xiao X, Tremblay JP. Expression of dog microdystrophin in mouse and dog muscles by gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1002-9. PMID 20179674 DOI: 10.1038/Mt.2010.23 |
0.418 |
|
2010 |
Zheng H, Qiao C, Wang CH, Li J, Li J, Yuan Z, Zhang C, Xiao X. Efficient retrograde transport of adeno-associated virus type 8 to spinal cord and dorsal root ganglion after vector delivery in muscle. Human Gene Therapy. 21: 87-97. PMID 19719401 DOI: 10.1089/Hum.2009.131 |
0.367 |
|
2010 |
Zhou L, Zhu T, Ye X, Yang L, Wang B, Liang X, Lu L, Tsao YP, Chen SL, Li J, Xiao X. Long-term protection against human papillomavirus e7-positive tumor by a single vaccination of adeno-associated virus vectors encoding a fusion protein of inactivated e7 of human papillomavirus 16/18 and heat shock protein 70. Human Gene Therapy. 21: 109-19. PMID 19715402 DOI: 10.1089/Hum.2009.139 |
0.332 |
|
2010 |
Qiao C, Li J, Zheng H, Bogan J, Li J, Yuan Z, Zhang C, Bogan D, Kornegay J, Xiao X. Hydrodynamic limb vein injection of adeno-associated virus serotype 8 vector carrying canine myostatin propeptide gene into normal dogs enhances muscle growth. Human Gene Therapy. 20: 1-10. PMID 18828709 DOI: 10.1089/Hum.2008.135 |
0.439 |
|
2010 |
Payne K, Lee H, Haleem A, Martin C, Xiao X, Chu C. 030 SINGLE INTRA-ARTICULAR INJECTION RESULTS IN STABLE AND CONTROLLABLE IN VIVO TRANSGENE EXPRESSION Osteoarthritis and Cartilage. 18: S22. DOI: 10.1016/S1063-4584(10)60057-X |
0.314 |
|
2010 |
Qiao C, Xiao X. Muscular dystrophy gene therapy in small animal models Muscle Gene Therapy. 55-68. DOI: 10.1007/978-1-4419-1207-7_4 |
0.354 |
|
2009 |
Yan W, Wang P, Zhao CX, Tang J, Xiao X, Wang DW. Decorin gene delivery inhibits cardiac fibrosis in spontaneously hypertensive rats by modulation of transforming growth factor-beta/Smad and p38 mitogen-activated protein kinase signaling pathways. Human Gene Therapy. 20: 1190-200. PMID 19697998 DOI: 10.1089/Hum.2008.204 |
0.339 |
|
2009 |
Yu CY, Yuan Z, Cao Z, Wang B, Qiao C, Li J, Xiao X. A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery. Gene Therapy. 16: 953-62. PMID 19474807 DOI: 10.1038/Gt.2009.59 |
0.385 |
|
2009 |
Koppanati BM, Li J, Xiao X, Clemens PR. Systemic delivery of AAV8 in utero results in gene expression in diaphragm and limb muscle: treatment implications for muscle disorders. Gene Therapy. 16: 1130-7. PMID 19474806 DOI: 10.1038/Gt.2009.71 |
0.431 |
|
2009 |
Yang L, Jiang J, Drouin LM, Agbandje-McKenna M, Chen C, Qiao C, Pu D, Hu X, Wang DZ, Li J, Xiao X. A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection. Proceedings of the National Academy of Sciences of the United States of America. 106: 3946-51. PMID 19234115 DOI: 10.1073/Pnas.0813207106 |
0.463 |
|
2009 |
Méjat A, Decostre V, Li J, Renou L, Kesari A, Hantaï D, Stewart CL, Xiao X, Hoffman E, Bonne G, Misteli T. Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy. The Journal of Cell Biology. 184: 31-44. PMID 19124654 DOI: 10.1083/Jcb.200811035 |
0.315 |
|
2009 |
Chen CC, Sun CP, Ma HI, Fang CC, Wu PY, Xiao X, Tao MH. Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 352-9. PMID 19066602 DOI: 10.1038/Mt.2008.245 |
0.341 |
|
2009 |
Wang B, Li J, Fu FH, Xiao X. Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 421-6. PMID 18973234 DOI: 10.1002/Jor.20781 |
0.431 |
|
2009 |
Wang T, Hou LB, Liu ZJ, Wang Y, Chen CL, Xiao X, Wang DW. Intramuscular delivery of rAAV-mediated kallikrein gene reduces hypertension and prevents cardiovascular injuries in model rats. Acta Pharmacologica Sinica. 28: 1898-906. PMID 18031602 DOI: 10.1111/J.1745-7254.2007.00677.X |
0.341 |
|
2008 |
Pan T, Cai M, Tang L, Zhou LQ, Li BJ, Zhu T, Li HZ, Li SY, Xiao X, Chen ZS. A novel approach of prophylaxis to HBV recurrence after liver transplantation. Virology. 382: 1-9. PMID 18945464 DOI: 10.1016/J.Virol.2008.06.024 |
0.303 |
|
2008 |
Wu B, Moulton HM, Iversen PL, Jiang J, Li J, Li J, Spurney CF, Sali A, Guerron AD, Nagaraju K, Doran T, Lu P, Xiao X, Lu QL. Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer. Proceedings of the National Academy of Sciences of the United States of America. 105: 14814-9. PMID 18806224 DOI: 10.1073/Pnas.0805676105 |
0.376 |
|
2008 |
Li J, Sun W, Wang B, Xiao X, Liu XQ. Protein trans-splicing as a means for viral vector-mediated in vivo gene therapy. Human Gene Therapy. 19: 958-964. PMID 18788906 DOI: 10.1089/Hum.2008.009 |
0.449 |
|
2008 |
Wang B, Li J, Fu FH, Chen C, Zhu X, Zhou L, Jiang X, Xiao X. Construction and analysis of compact muscle-specific promoters for AAV vectors Gene Therapy. 15: 1489-1499. PMID 18563184 DOI: 10.1038/Gt.2008.104 |
0.402 |
|
2008 |
Rehman KK, Trucco M, Wang Z, Xiao X, Robbins PD. AAV8-mediated gene transfer of interleukin-4 to endogenous beta-cells prevents the onset of diabetes in NOD mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1409-16. PMID 18560422 DOI: 10.1038/Mt.2008.116 |
0.351 |
|
2008 |
Levicoff EA, Kim JS, Sobajima S, Wallach CJ, Larson JW, Robbins PD, Xiao X, Juan L, Vadala G, Gilbertson LG, Kang JD. Safety assessment of intradiscal gene therapy II: effect of dosing and vector choice. Spine. 33: 1509-16; discussion . PMID 18520636 DOI: 10.1097/Brs.0B013E318178866C |
0.407 |
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2008 |
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1996 |
Xiao X, Li J, Samulski RJ. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector Journal of Virology. 70: 8098-8108. PMID 8892935 DOI: 10.1128/Jvi.70.11.8098-8108.1996 |
0.48 |
|
1996 |
McCown TJ, Xiao X, Li J, Breese GR, Samulski RJ. Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Research. 713: 99-107. PMID 8724980 DOI: 10.1016/0006-8993(95)01488-8 |
0.399 |
|
1994 |
Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O'Malley KL, During MJ. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nature Genetics. 8: 148-54. PMID 7842013 DOI: 10.1038/Ng1094-148 |
0.424 |
|
1994 |
Goodman S, Xiao X, Donahue R, Moulton A, Miller J, Walsh C, Young N, Samulski R, Nienhuis A. Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells [published erratum appears in Blood 1995 Feb 1;85(3):862] Blood. 84: 1492-1500. DOI: 10.1182/Blood.V84.5.1492.Bloodjournal8451492 |
0.423 |
|
1993 |
Snyder RO, Im DS, Ni T, Xiao X, Samulski RJ, Muzyczka N. Features of the adeno-associated virus origin involved in substrate recognition by the viral rep protein Journal of Virology. 67: 6096-6104. PMID 8396670 DOI: 10.1128/Jvi.67.10.6096-6104.1993 |
0.536 |
|
1992 |
Walsh CE, Liu JM, Xiao X, Young NS, Nienhuis AW, Samulski RJ. Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. Proceedings of the National Academy of Sciences of the United States of America. 89: 7257-61. PMID 1323131 DOI: 10.1073/Pnas.89.15.7257 |
0.421 |
|
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