| Year |
Citation |
Score |
| 2023 |
Miller MS, Cowan AD, Brouwer JM, Smyth ST, Peng L, Wardak AZ, Uren RT, Luo C, Roy MJ, Shah S, Tan Z, Reid GE, Colman PM, Czabotar PE. Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. The Febs Journal. PMID 38088212 DOI: 10.1111/febs.17031 |
0.337 |
|
| 2021 |
Roy MJ, Vom A, Okamoto T, Smith BJ, Birkinshaw RW, Yang H, Abdo H, White CA, Segal D, Huang DCS, Baell JB, Colman PM, Czabotar PE, Lessene G. Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-X and BCL-2. Journal of Medicinal Chemistry. PMID 33904752 DOI: 10.1021/acs.jmedchem.0c01771 |
0.315 |
|
| 2019 |
Fitzsimmons L, Cartlidge R, Chang C, Sejic N, Galbraith LCA, Suraweera CD, Croom-Carter D, Dewson G, Tierney RJ, Bell AI, Shannon-Lowe C, Herold MJ, Rickinson AB, Colman PM, Huang DCS, et al. EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins. Cell Death and Differentiation. PMID 31645677 DOI: 10.1038/S41418-019-0435-1 |
0.682 |
|
| 2019 |
van Delft MF, Chappaz S, Khakham Y, Bui CT, Debrincat MA, Lowes KN, Brouwer JM, Grohmann C, Sharp PP, Dagley LF, Li L, McArthur K, Luo MX, Chin HS, Fairlie WD, ... ... Colman PM, et al. A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis. Nature Chemical Biology. PMID 31591564 DOI: 10.1038/S41589-019-0365-8 |
0.342 |
|
| 2016 |
Lee EF, Grabow S, Chappaz S, Dewson G, Hockings C, Kluck RM, Gray DH, Witkowski MT, Evangelista M, Pettikiriarachchi A, Bouillet P, Lane RM, Czabotar PE, Colman PM, Smith BJ, et al. Physiological restraint of Bak by Bcl-xL is essential for cell survival. Genes & Development. PMID 27198225 DOI: 10.1101/gad.279414.116 |
0.36 |
|
| 2016 |
Cowan AD, Colman PM, Czabotar PE. Structural and functional characterisation of Bok, a pro-apoptotic Bcl-2 effector protein Acta Crystallographica Section a Foundations and Advances. 72: s237-s237. DOI: 10.1107/S2053273316096406 |
0.357 |
|
| 2015 |
Marshall B, Puthalakath H, Caria S, Chugh S, Doerflinger M, Colman PM, Kvansakul M. Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim. Cell Death & Disease. 6: e1680. PMID 25766319 DOI: 10.1038/Cddis.2015.52 |
0.723 |
|
| 2014 |
Lee EF, Dewson G, Evangelista M, Pettikiriarachchi A, Gold GJ, Zhu H, Colman PM, Fairlie WD. The functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains. The Journal of Biological Chemistry. 289: 36001-17. PMID 25371206 DOI: 10.1074/jbc.M114.610758 |
0.392 |
|
| 2014 |
Campbell S, Thibault J, Mehta N, Colman PM, Barry M, Kvansakul M. Structural insight into BH3 domain binding of vaccinia virus antiapoptotic F1L. Journal of Virology. 88: 8667-77. PMID 24850748 DOI: 10.1128/Jvi.01092-14 |
0.718 |
|
| 2014 |
Czabotar P, Brouwer J, Westphal D, Thompson G, Colman P. Crystal structures of Bax and Bak Reveal Molecular Events Initiating Apoptosis Acta Crystallographica Section A. 70. DOI: 10.1107/S205327331408509X |
0.366 |
|
| 2013 |
Sleebs BE, Kersten WJ, Kulasegaram S, Nikolakopoulos G, Hatzis E, Moss RM, Parisot JP, Yang H, Czabotar PE, Fairlie WD, Lee EF, Adams JM, Chen L, van Delft MF, Lowes KN, ... ... Colman PM, et al. Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL. Journal of Medicinal Chemistry. 56: 5514-40. PMID 23767404 DOI: 10.1021/Jm400556W |
0.314 |
|
| 2013 |
Czabotar PE, Westphal D, Dewson G, Ma S, Hockings C, Fairlie WD, Lee EF, Yao S, Robin AY, Smith BJ, Huang DC, Kluck RM, Adams JM, Colman PM. Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis. Cell. 152: 519-31. PMID 23374347 DOI: 10.1016/J.Cell.2012.12.031 |
0.342 |
|
| 2012 |
Okamoto T, Campbell S, Mehta N, Thibault J, Colman PM, Barry M, Huang DC, Kvansakul M. Sheeppox virus SPPV14 encodes a Bcl-2-like cell death inhibitor that counters a distinct set of mammalian proapoptotic proteins. Journal of Virology. 86: 11501-11. PMID 22896610 DOI: 10.1128/Jvi.01115-12 |
0.71 |
|
| 2011 |
Lee EF, Dewson G, Smith BJ, Evangelista M, Pettikiriarachchi A, Dogovski C, Perugini MA, Colman PM, Fairlie WD. Crystal structure of a BCL-W domain-swapped dimer: implications for the function of BCL-2 family proteins. Structure (London, England : 1993). 19: 1467-76. PMID 22000515 DOI: 10.1016/j.str.2011.07.015 |
0.338 |
|
| 2011 |
Czabotar PE, Lee EF, Thompson GV, Wardak AZ, Fairlie WD, Colman PM. Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis. The Journal of Biological Chemistry. 286: 7123-31. PMID 21199865 DOI: 10.1074/jbc.M110.161281 |
0.409 |
|
| 2011 |
Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DCS, Colman PM. Structural basis for the inhibition of apoptosis by Epstein–Barr virus BHRF1 Acta Crystallographica Section A. 67: 76-76. DOI: 10.1107/S010876731109814X |
0.681 |
|
| 2010 |
Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DC, Colman PM. Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1. Plos Pathogens. 6: e1001236. PMID 21203485 DOI: 10.1371/Journal.Ppat.1001236 |
0.684 |
|
| 2010 |
Campbell S, Hazes B, Kvansakul M, Colman P, Barry M. Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. The Journal of Biological Chemistry. 285: 4695-708. PMID 19955184 DOI: 10.1074/Jbc.M109.053769 |
0.693 |
|
| 2010 |
COLMAN PM. ChemInform Abstract: Design and Antiviral Properties of Influenza Virus Neuraminidase Inhibitors Cheminform. 27: no-no. DOI: 10.1002/CHIN.199611340 |
0.309 |
|
| 2009 |
Lee EF, Fedorova A, Zobel K, Boyle MJ, Yang H, Perugini MA, Colman PM, Huang DC, Deshayes K, Fairlie WD. Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins. The Journal of Biological Chemistry. 284: 31315-26. PMID 19748896 DOI: 10.1074/jbc.M109.048009 |
0.321 |
|
| 2009 |
Lee EF, Czabotar PE, Yang H, Sleebs BE, Lessene G, Colman PM, Smith BJ, Fairlie WD. Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands. The Journal of Biological Chemistry. 284: 30508-17. PMID 19726685 DOI: 10.1074/jbc.M109.040725 |
0.327 |
|
| 2009 |
Hodder AN, Malby RL, Clarke OB, Fairlie WD, Colman PM, Crabb BS, Smith BJ. Structural insights into the protease-like antigen Plasmodium falciparum SERA5 and its noncanonical active-site serine. Journal of Molecular Biology. 392: 154-65. PMID 19591843 DOI: 10.1016/j.jmb.2009.07.007 |
0.301 |
|
| 2009 |
Czabotar PE, Colman PM, Huang DC. Bax activation by Bim? Cell Death and Differentiation. 16: 1187-91. PMID 19557009 DOI: 10.1038/cdd.2009.83 |
0.358 |
|
| 2008 |
Lee EF, Chen L, Yang H, Colman PM, Huang DC, Fairlie WD. EGL-1 BH3 mutants reveal the importance of protein levels and target affinity for cell-killing potency. Cell Death and Differentiation. 15: 1609-18. PMID 18566606 DOI: 10.1038/cdd.2008.86 |
0.368 |
|
| 2008 |
Kvansakul M, Yang H, Fairlie WD, Czabotar PE, Fischer SF, Perugini MA, Huang DCS, Colman PM. Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands Cell Death and Differentiation. 15: 1564-1571. PMID 18551131 DOI: 10.1038/Cdd.2008.83 |
0.7 |
|
| 2008 |
Dewson G, Kratina T, Sim HW, Puthalakath H, Adams JM, Colman PM, Kluck RM. To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions. Molecular Cell. 30: 369-80. PMID 18471982 DOI: 10.1016/J.Molcel.2008.04.005 |
0.307 |
|
| 2008 |
Lee EF, Czabotar PE, van Delft MF, Michalak EM, Boyle MJ, Willis SN, Puthalakath H, Bouillet P, Colman PM, Huang DC, Fairlie WD. A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation. The Journal of Cell Biology. 180: 341-55. PMID 18209102 DOI: 10.1083/jcb.200708096 |
0.309 |
|
| 2008 |
Czabotar P, Lee E, Fairlie W, Colman P. How programmed cell death is regulated: insights from structures of Bcl-2 family protein complexes Acta Crystallographica Section a Foundations of Crystallography. 64: C79-C79. DOI: 10.1107/S010876730809747X |
0.304 |
|
| 2008 |
Kvansakul M, Delft MFv, Yang H, Lee EF, Fairlie WD, Czabotar PE, Gulbis JM, Fischer SF, Perugini MA, Huang DC, Colman PM. Insight into viral inhibition of apoptosis – structures of myxoma virus M11L and vaccinia virus F1L Acta Crystallographica Section A. 64: 328-328. DOI: 10.1107/S0108767308089502 |
0.671 |
|
| 2007 |
Czabotar PE, Lee EF, van Delft MF, Day CL, Smith BJ, Huang DC, Fairlie WD, Hinds MG, Colman PM. Structural insights into the degradation of Mcl-1 induced by BH3 domains. Proceedings of the National Academy of Sciences of the United States of America. 104: 6217-22. PMID 17389404 DOI: 10.1073/pnas.0701297104 |
0.399 |
|
| 2007 |
Kvansakul M, van Delft MF, Lee EF, Gulbis JM, Fairlie WD, Huang DC, Colman PM. A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak. Molecular Cell. 25: 933-42. PMID 17386268 DOI: 10.1016/J.Molcel.2007.02.004 |
0.714 |
|
| 2006 |
Fairlie WD, Perugini MA, Kvansakul M, Chen L, Huang DCS, Colman PM. CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13 Cell Death & Differentiation. 13: 426-434. PMID 16167070 DOI: 10.1038/Sj.Cdd.4401762 |
0.618 |
|
| 2005 |
Adams JM, Huang DC, Strasser A, Willis S, Chen L, Wei A, van Delft M, Fletcher JI, Puthalakath H, Kuroda J, Michalak EM, Kelly PN, Bouillet P, Villunger A, O'Reilly L, ... ... Colman P, et al. Subversion of the Bcl-2 life/death switch in cancer development and therapy. Cold Spring Harbor Symposia On Quantitative Biology. 70: 469-77. PMID 16869785 DOI: 10.1101/Sqb.2005.70.009 |
0.472 |
|
| 2005 |
Colman P. Zanamivir: an influenza virus neuraminidase inhibitor. Expert Review of Anti-Infective Therapy. 3: 191-199. PMID 15918777 DOI: 10.1586/14787210.3.2.191 |
0.356 |
|
| 2005 |
Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DC. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Molecular Cell. 17: 393-403. PMID 15694340 DOI: 10.1016/J.Molcel.2004.12.030 |
0.381 |
|
| 2004 |
Lawrence MC, Borg NA, Streltsov VA, Pilling PA, Epa VC, Varghese JN, McKimm-Breschkin JL, Colman PM. Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III. Journal of Molecular Biology. 335: 1343-57. PMID 14729348 DOI: 10.1016/j.jmb.2003.11.032 |
0.382 |
|
| 2004 |
McKimm-Breschkin JL, Colman PM, Jin B, Krippner GY, McDonald M, Reece PA, Tucker SP, Waddington L, Watson KG, Wu WY. Tethered neuraminidase inhibitors that bind an influenza virus: a first step towards a diagnostic method for influenza. Angewandte Chemie (International Ed. in English). 42: 3118-21. PMID 12866095 DOI: 10.1002/ANIE.200250402 |
0.31 |
|
| 2002 |
Colman PM. Neuraminidase inhibitors as antivirals. Vaccine. S55-8. PMID 12110259 DOI: 10.1016/S0264-410X(02)00132-9 |
0.303 |
|
| 2002 |
Smith BJ, Lawrence MC, Colman PM. Modelling the structure of the fusion protein from human respiratory syncytial virus. Protein Engineering. 15: 365-71. PMID 12034856 DOI: 10.1093/PROTEIN/15.5.365 |
0.372 |
|
| 2002 |
Smith BJ, McKimm-Breshkin JL, McDonald M, Fernley RT, Varghese JN, Colman PM. Structural studies of the resistance of influenza virus neuramindase to inhibitors. Journal of Medicinal Chemistry. 45: 2207-12. PMID 12014958 DOI: 10.1021/JM010528U |
0.334 |
|
| 2002 |
Colman P. The influenza virus antigen, neuraminidase Acta Crystallographica Section a Foundations of Crystallography. 58: c34-c34. DOI: 10.1107/S0108767302086464 |
0.308 |
|
| 2000 |
Colman PM. A novel approach to antiviral therapy for influenza. The Journal of Antimicrobial Chemotherapy. 17-22. PMID 10877458 DOI: 10.1093/JAC/44.SUPPL_2.17 |
0.321 |
|
| 1998 |
Varghese JN, Smith PW, Sollis SL, Blick TJ, Sahasrabudhe A, McKimm-Breschkin JL, Colman PM. Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure (London, England : 1993). 6: 735-46. PMID 9655825 DOI: 10.1016/S0969-2126(98)00075-6 |
0.351 |
|
| 1998 |
Taylor NR, Cleasby A, Singh O, Skarzynski T, Wonacott AJ, Smith PW, Sollis SL, Howes PD, Cherry PC, Bethell R, Colman P, Varghese J. Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B. Journal of Medicinal Chemistry. 41: 798-807. PMID 9526556 DOI: 10.1021/Jm9703754 |
0.431 |
|
| 1997 |
Colman P. Virus versus antibody Structure. 5: 591-593. PMID 9235220 DOI: 10.1016/S0969-2126(97)00214-1 |
0.472 |
|
| 1996 |
Itzstein Mv, Colman P. Design and synthesis of carbohydrate-based inhibitors of protein-carbohydrate interactions. Current Opinion in Structural Biology. 6: 703-709. PMID 8913694 DOI: 10.1016/S0959-440X(96)80038-8 |
0.361 |
|
| 1996 |
Varghese JN, Colman PM, Blick TJ, Tiong T, Sahasrabudhe S, McKimm-Breschkin JL. An influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase inhibitor 4-guanidino-Neu5Ac2en Acta Crystallographica Section a Foundations of Crystallography. 52: C200-C200. DOI: 10.1107/S0108767396091350 |
0.326 |
|
| 1996 |
Smith PW, Sollis SL, Howes PD, Cherry PC, Cobley KN, Taylor H, Whittington AR, Scicinski J, Bethell RC, Taylor N, Skarzynski T, Cleasby A, Singh O, Wonacott A, Varghese J, ... Colman P, et al. Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides Bioorganic & Medicinal Chemistry Letters. 6: 2931-2936. DOI: 10.1016/S0960-894X(96)00542-2 |
0.346 |
|
| 1995 |
Blick TJ, Tiong T, Sahasrabudhe A, Varghese JN, Colman PM, Hart GJ, Bethell RC, McKimm-Breschkin JL. Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en. Virology. 214: 475-84. PMID 8553549 DOI: 10.1006/viro.1995.0058 |
0.35 |
|
| 1995 |
Colman PM. Influenza virus neuraminidase: structure, antibodies, and inhibitors. Protein Science : a Publication of the Protein Society. 3: 1687-96. PMID 7849585 DOI: 10.1002/PRO.5560031007 |
0.356 |
|
| 1995 |
Varghese JN, Epa VC, Colman PM. Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase. Protein Science : a Publication of the Protein Society. 4: 1081-7. PMID 7549872 DOI: 10.1002/PRO.5560040606 |
0.31 |
|
| 1995 |
Colman PM. Design and antiviral properties of influenza virus neuraminidase inhibitors Pure and Applied Chemistry. 67: 1683-1688. DOI: 10.1351/pac199567101683 |
0.315 |
|
| 1993 |
Von Itzstein M, Wu WY, Kok GB, Pegg MS, Dyason JC, Jin B, Van Phan T, Smythe ML, White HF, Oliver SW, Colman PM, Varghese JN, Ryan DM, Woods JM, Bethell RC, et al. Rational design of potent sialidase-based inhibitors of influenza virus replication Nature. 363: 418-423. PMID 8502295 DOI: 10.1038/363418A0 |
0.332 |
|
| 1993 |
Colman PM, Hoyne PA, Lawrence MC. Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase. Journal of Virology. 67: 2972-80. PMID 8497041 |
0.335 |
|
| 1993 |
Colman PM, Varghese JN, von Itzstein M, Penn CR. Design and properties of inhibitors of influenza virus neuraminidase Acta Crystallographica Section a Foundations of Crystallography. 49: c159-c160. DOI: 10.1107/S0108767378095434 |
0.306 |
|
| 1992 |
Colman P. Structural basis of antigenic variation: studies of influenza virus neuraminidase. Immunology and Cell Biology. 70: 209-214. PMID 1452222 DOI: 10.1038/Icb.1992.26 |
0.431 |
|
| 1988 |
Varghese JN, Webster RG, Laver WG, Colman PM. Structure of an escape mutant of glycoprotein N2 neuraminidase of influenza virus A/Tokyo/3/67 at 3 A. Journal of Molecular Biology. 200: 201-3. PMID 3379640 DOI: 10.1016/0022-2836(88)90344-0 |
0.337 |
|
| 1988 |
Laver W, Colman P, Webster R, Air G. The crystal structure of antibodies complexed with influenza virus neuraminidase (NA) Virus Research. 11: 9. DOI: 10.1016/0168-1702(88)90115-3 |
0.4 |
|
| 1987 |
Baker AT, Varghese JN, Laver WG, Air GM, Colman PM. Three-dimensional structure of neuraminidase of subtype N9 from an avian influenza virus. Proteins. 2: 111-7. PMID 3447170 DOI: 10.1002/Prot.340020205 |
0.325 |
|
| 1987 |
Varghese JN, Colman PM, Laver WG, Webster RG. The structure of the neuraminidase glycoprotein of influenza virus (Tokyo/3/67) at 2.4 Å resolution Acta Crystallographica Section a Foundations of Crystallography. 43: C20-C20. DOI: 10.1107/S0108767387084964 |
0.352 |
|
| 1987 |
Colman PM, Varghese JN, Baker AT, Tulloch PA, Laver WG, Air GM, Webster RG. The structure of a complex between influenza virus neuraminidase and an antibody Acta Crystallographica Section a Foundations of Crystallography. 43: C34-C35. DOI: 10.1107/S0108767387084538 |
0.32 |
|
| 1985 |
Colman PM, Ward CW. Structure and diversity of influenza virus neuraminidase. Current Topics in Microbiology and Immunology. 114: 177-255. PMID 2581739 DOI: 10.1007/978-3-642-70227-3_5 |
0.353 |
|
| 1983 |
Varghese JN, Laver WG, Colman PM. Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 A resolution. Nature. 303: 35-40. PMID 6843658 DOI: 10.1038/303035A0 |
0.31 |
|
| 1982 |
Colman PM, Gough KH, Lilley GG, Blagrove RJ, Webster RG, Laver WG. Crystalline monoclonal fab fragment with specificity towards an influenza virus neuraminidase. Journal of Molecular Biology. 152: 609-14. PMID 7328664 DOI: 10.1016/0022-2836(81)90272-2 |
0.331 |
|
| 1974 |
Epp O, Colman P, Fehlhammer H, Bode W, Schiffer M, Huber R, Palm W. Crystal and molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI. European Journal of Biochemistry. 45: 513-24. PMID 4851220 DOI: 10.1111/J.1432-1033.1974.Tb03576.X |
0.329 |
|
| Show low-probability matches. |