| Year |
Citation |
Score |
| 2020 |
Akdemir KC, Le VT, Chandran S, Li Y, Verhaak RG, Beroukhim R, Campbell PJ, Chin L, Dixon JR, Futreal PA. Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer. Nature Genetics. PMID 32024999 DOI: 10.1038/S41588-019-0564-Y |
0.311 |
|
| 2019 |
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu CJ, Sadanandam A, Hu B, Chang Q, Chu GC, Al-Khalil R, Jiang S, Xia H, ... ... Chin L, et al. Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer. Cell. 179: 1239. PMID 31730860 DOI: 10.1016/J.Cell.2019.10.037 |
0.456 |
|
| 2018 |
Zhang Y, Yang L, Kucherlapati M, Chen F, Hadjipanayis A, Pantazi A, Bristow CA, Lee EA, Mahadeshwar HS, Tang J, Zhang J, Seth S, Lee S, Ren X, Song X, ... ... Chin L, et al. A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases. Cell Reports. 24: 515-527. PMID 29996110 DOI: 10.1016/J.Celrep.2018.06.025 |
0.343 |
|
| 2017 |
Ong DST, Hu B, Ho YW, Sauvé CG, Bristow CA, Wang Q, Multani AS, Chen P, Nezi L, Jiang S, Gorman CE, Monasterio MM, Koul D, Marchesini M, Colla S, ... ... Chin L, et al. PAF promotes stemness and radioresistance of glioma stem cells. Proceedings of the National Academy of Sciences of the United States of America. 114: E9086-E9095. PMID 29073105 DOI: 10.1073/Pnas.1708122114 |
0.477 |
|
| 2017 |
Sarkar S, Bristow CA, Dey P, Rai K, Perets R, Ramirez-Cardenas A, Malasi S, Huang-Hobbs E, Haemmerle M, Wu SY, McGuire M, Protopopov A, Jiang S, Liu JF, Hirsch MS, ... ... Chin L, et al. PRKCI promotes immune suppression in ovarian cancer. Genes & Development. PMID 28698296 DOI: 10.1101/Gad.296640.117 |
0.547 |
|
| 2017 |
Zhang Y, Kwok-Shing Ng P, Kucherlapati M, Chen F, Liu Y, Tsang YH, de Velasco G, Jeong KJ, Akbani R, Hadjipanayis A, Pantazi A, Bristow CA, Lee E, Mahadeshwar HS, Tang J, ... ... Chin L, et al. A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations. Cancer Cell. PMID 28528867 DOI: 10.1016/J.Ccell.2017.04.013 |
0.327 |
|
| 2017 |
Eskiocak B, McMillan E, Mendiratta S, Kollipara R, Zhang H, Humphries C, Wang C, Garcia-Rodriguez J, Ding M, Zaman A, Rosales T, Eskiocak U, Smith MP, Sudderth J, Komurov K, ... ... Chin L, et al. Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma. Cancer Discovery. PMID 28455392 DOI: 10.1158/2159-8290.Cd-16-0955 |
0.328 |
|
| 2017 |
Genovese G, Carugo A, Tepper J, Robinson FS, Li L, Svelto M, Nezi L, Corti D, Minelli R, Pettazzoni P, Gutschner T, Wu CC, Seth S, Akdemir KC, Leo E, ... ... Chin L, et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. PMID 28178232 DOI: 10.1038/Nature21064 |
0.537 |
|
| 2016 |
Hu B, Wang Q, Wang YA, Hua S, Sauvé CG, Ong D, Lan ZD, Chang Q, Ho YW, Monasterio MM, Lu X, Zhong Y, Zhang J, Deng P, Tan Z, ... ... Chin L, et al. Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth. Cell. 167: 1281-1295.e18. PMID 27863244 DOI: 10.1016/J.Cell.2016.10.039 |
0.517 |
|
| 2016 |
Carugo A, Genovese G, Seth S, Nezi L, Rose JL, Bossi D, Cicalese A, Shah PK, Viale A, Pettazzoni PF, Akdemir KC, Bristow CA, Robinson FS, Tepper J, Sanchez N, ... ... Chin L, et al. In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer. Cell Reports. PMID 27320920 DOI: 10.1016/J.Celrep.2016.05.063 |
0.528 |
|
| 2016 |
Lissanu Deribe Y, Shi Y, Rai K, Nezi L, Amin SB, Wu CC, Akdemir KC, Mahdavi M, Peng Q, Chang QE, Hornigold K, Arold ST, Welch HC, Garraway LA, Chin L. Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884185 DOI: 10.1073/Pnas.1513801113 |
0.342 |
|
| 2015 |
Wang G, Lu X, Dey P, Deng P, Wu CC, Jiang S, Fang Z, Zhao K, Konaparthi R, Hua S, Zhang J, Li-Ning-Tapia EM, Kapoor A, Wu CJ, Patel NB, ... ... Chin L, et al. Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression. Cancer Discovery. PMID 26701088 DOI: 10.1186/2051-1426-3-S2-P421 |
0.52 |
|
| 2015 |
Rondinelli B, Rosano D, Antonini E, Frenquelli M, Montanini L, Huang D, Segalla S, Yoshihara K, Amin SB, Lazarevic D, The BT, Verhaak RG, Futreal PA, Di Croce L, Chin L, et al. Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer. The Journal of Clinical Investigation. PMID 26551685 DOI: 10.1172/JCI81040 |
0.324 |
|
| 2015 |
Rai K, Akdemir KC, Kwong LN, Fiziev P, Wu CJ, Keung EZ, Sharma S, Samant NS, Williams M, Axelrad JB, Shah A, Yang D, Grimm EA, Barton MC, Milton DR, ... ... Chin L, et al. Dual Roles of RNF2 in Melanoma Progression. Cancer Discovery. PMID 26450788 DOI: 10.1158/2159-8290.Cd-15-0493 |
0.327 |
|
| 2015 |
Muller F, Colla S, Aquilanti E, Manzo VE, Genovese G, Lee J, Eisenson D, Narurkar R, Deng P, Nezi L, Lee M, Hu B, Hu J, Sahin E, Ong D, ... ... Chin L, et al. Corrigendum: Passenger deletions generate therapeutic vulnerabilities in cancer. Nature. PMID 26153864 DOI: 10.1038/Nature14609 |
0.385 |
|
| 2015 |
Colla S, Ong DS, Ogoti Y, Marchesini M, Mistry NA, Clise-Dwyer K, Ang SA, Storti P, Viale A, Giuliani N, Ruisaard K, Ganan Gomez I, Bristow CA, Estecio M, Weksberg DC, ... ... Chin L, et al. Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome. Cancer Cell. 27: 644-57. PMID 25965571 DOI: 10.1016/J.Ccell.2015.04.007 |
0.462 |
|
| 2015 |
Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, Laird PW, ... ... Chin L, et al. Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution. Genome Research. 25: 316-27. PMID 25650244 DOI: 10.1101/Gr.180612.114 |
0.33 |
|
| 2014 |
Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, ... ... Chin L, et al. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell. 26: 319-30. PMID 25155756 DOI: 10.1016/J.Ccr.2014.07.014 |
0.318 |
|
| 2014 |
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu CJ, Sadanandam A, Hu B, Chang Q, Chu GC, Al-Khalil R, Jiang S, Xia H, ... ... Chin L, et al. Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer. Cell. 158: 185-97. PMID 24954535 DOI: 10.1016/J.Cell.2014.06.003 |
0.55 |
|
| 2014 |
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, et al. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 25: 719-34. PMID 24856586 DOI: 10.1016/J.Ccr.2014.04.005 |
0.329 |
|
| 2014 |
Mertz KD, Pathria G, Wagner C, Saarikangas J, Sboner A, Romanov J, Gschaider M, Lenz F, Neumann F, Schreiner W, Nemethova M, Glassmann A, Lappalainen P, Stingl G, Small JV, ... ... Chin L, et al. MTSS1 is a metastasis driver in a subset of human melanomas. Nature Communications. 5: 3465. PMID 24632752 DOI: 10.1038/Ncomms4465 |
0.36 |
|
| 2014 |
Kwong LN, Chin L. Chromosome 10, frequently lost in human melanoma, encodes multiple tumor-suppressive functions. Cancer Research. 74: 1814-21. PMID 24453001 DOI: 10.1158/0008-5472.Can-13-1446 |
0.309 |
|
| 2013 |
Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, ... ... Chin L, et al. The somatic genomic landscape of glioblastoma. Cell. 155: 462-77. PMID 24120142 DOI: 10.1016/J.Cell.2013.09.034 |
0.347 |
|
| 2013 |
Hu J, Ho AL, Yuan L, Hu B, Hua S, Hwang SS, Zhang J, Hu T, Zheng H, Gan B, Wu G, Wang YA, Chin L, DePinho RA. From the Cover: Neutralization of terminal differentiation in gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 14520-7. PMID 23918370 DOI: 10.1073/Pnas.1308610110 |
0.533 |
|
| 2013 |
Zheng S, Fu J, Vegesna R, Mao Y, Heathcock LE, Torres-Garcia W, Ezhilarasan R, Wang S, McKenna A, Chin L, Brennan CW, Yung WK, Weinstein JN, Aldape KD, Sulman EP, et al. A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival. Genes & Development. 27: 1462-72. PMID 23796897 DOI: 10.1101/Gad.213686.113 |
0.372 |
|
| 2012 |
Quayle SN, Lee JY, Cheung LW, Ding L, Wiedemeyer R, Dewan RW, Huang-Hobbs E, Zhuang L, Wilson RK, Ligon KL, Mills GB, Cantley LC, Chin L. Somatic mutations of PIK3R1 promote gliomagenesis. Plos One. 7: e49466. PMID 23166678 DOI: 10.1371/Journal.Pone.0049466 |
0.307 |
|
| 2012 |
Muller FL, Colla S, Aquilanti E, Manzo VE, Genovese G, Lee J, Eisenson D, Narurkar R, Deng P, Nezi L, Lee MA, Hu B, Hu J, Sahin E, Ong D, ... ... Chin L, et al. Passenger deletions generate therapeutic vulnerabilities in cancer. Nature. 488: 337-42. PMID 22895339 DOI: 10.1038/Nature11331 |
0.533 |
|
| 2012 |
Larman TC, DePalma SR, Hadjipanayis AG, Protopopov A, Zhang J, Gabriel SB, Chin L, Seidman CE, Kucherlapati R, Seidman JG. Spectrum of somatic mitochondrial mutations in five cancers. Proceedings of the National Academy of Sciences of the United States of America. 109: 14087-91. PMID 22891333 DOI: 10.1073/Pnas.1211502109 |
0.309 |
|
| 2012 |
Chen AJ, Paik JH, Zhang H, Shukla SA, Mortensen R, Hu J, Ying H, Hu B, Hurt J, Farny N, Dong C, Xiao Y, Wang YA, Silver PA, Chin L, et al. STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA. Genes & Development. 26: 1459-72. PMID 22751500 DOI: 10.1101/Gad.189001.112 |
0.506 |
|
| 2012 |
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, ... ... Chin L, et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell. 149: 656-70. PMID 22541435 DOI: 10.1016/J.Cell.2012.01.058 |
0.489 |
|
| 2012 |
Dunn GP, Rinne ML, Wykosky J, Genovese G, Quayle SN, Dunn IF, Agarwalla PK, Chheda MG, Campos B, Wang A, Brennan C, Ligon KL, Furnari F, Cavenee WK, Depinho RA, ... Chin L, et al. Emerging insights into the molecular and cellular basis of glioblastoma. Genes & Development. 26: 756-84. PMID 22508724 DOI: 10.1101/Gad.187922.112 |
0.476 |
|
| 2012 |
Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A, Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, ... ... Chin L, et al. Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases. Cell. 148: 896-907. PMID 22341455 DOI: 10.1016/J.Cell.2012.01.039 |
0.552 |
|
| 2012 |
Hu J, Hwang SS, Liesa M, Gan B, Sahin E, Jaskelioff M, Ding Z, Ying H, Boutin AT, Zhang H, Johnson S, Ivanova E, Kost-Alimova M, Protopopov A, Wang YA, ... ... Chin L, et al. Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer. Cell. 148: 651-63. PMID 22341440 DOI: 10.1016/J.Cell.2011.12.028 |
0.541 |
|
| 2011 |
Li M, Mukasa A, Inda MM, Zhang J, Chin L, Cavenee W, Furnari F. Guanylate binding protein 1 is a novel effector of EGFR-driven invasion in glioblastoma. The Journal of Experimental Medicine. 208: 2657-73. PMID 22162832 DOI: 10.1084/Jem.20111102 |
0.31 |
|
| 2011 |
Ying H, Elpek KG, Vinjamoori A, Zimmerman SM, Chu GC, Yan H, Fletcher-Sananikone E, Zhang H, Liu Y, Wang W, Ren X, Zheng H, Kimmelman AC, Paik JH, Lim C, ... ... Chin L, et al. PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network. Cancer Discovery. 1: 158-69. PMID 21984975 DOI: 10.1158/2159-8290.Cd-11-0031 |
0.539 |
|
| 2011 |
Bass AJ, Lawrence MS, Brace LE, Ramos AH, Drier Y, Cibulskis K, Sougnez C, Voet D, Saksena G, Sivachenko A, Jing R, Parkin M, Pugh T, Verhaak RG, Stransky N, ... ... Chin L, et al. Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nature Genetics. 43: 964-8. PMID 21892161 DOI: 10.1038/Ng.936 |
0.528 |
|
| 2011 |
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, ... ... Chin L, et al. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nature Genetics. 43: 869-74. PMID 21804546 DOI: 10.1038/Ng.890 |
0.344 |
|
| 2011 |
Scott KL, Nogueira C, Heffernan TP, van Doorn R, Dhakal S, Hanna JA, Min C, Jaskelioff M, Xiao Y, Wu CJ, Cameron LA, Perry SR, Zeid R, Feinberg T, Kim M, ... ... Chin L, et al. Proinvasion metastasis drivers in early-stage melanoma are oncogenes. Cancer Cell. 20: 92-103. PMID 21741599 DOI: 10.1016/J.Ccr.2011.05.025 |
0.538 |
|
| 2011 |
Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, ... ... Chin L, et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature. 470: 359-65. PMID 21307849 DOI: 10.1038/Nature09787 |
0.446 |
|
| 2011 |
Ding Z, Wu CJ, Chu GC, Xiao Y, Ho D, Zhang J, Perry SR, Labrot ES, Wu X, Lis R, Hoshida Y, Hiller D, Hu B, Jiang S, Zheng H, ... ... Chin L, et al. SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression. Nature. 470: 269-73. PMID 21289624 DOI: 10.1038/Nature09677 |
0.47 |
|
| 2010 |
Gan B, Hu J, Jiang S, Liu Y, Sahin E, Zhuang L, Fletcher-Sananikone E, Colla S, Wang YA, Chin L, Depinho RA. Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature. 468: 701-4. PMID 21124456 DOI: 10.1038/Nature09595 |
0.467 |
|
| 2010 |
Stegh AH, Brennan C, Mahoney JA, Forloney KL, Jenq HT, Luciano JP, Protopopov A, Chin L, Depinho RA. Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor. Genes & Development. 24: 2194-204. PMID 20837658 DOI: 10.1101/Gad.1924710 |
0.515 |
|
| 2010 |
Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, ... ... Chin L, et al. Towards patient-based cancer therapeutics. Nature Biotechnology. 28: 904-6. PMID 20829823 DOI: 10.1038/Nbt0910-904 |
0.535 |
|
| 2010 |
Wiedemeyer WR, Dunn IF, Quayle SN, Zhang J, Chheda MG, Dunn GP, Zhuang L, Rosenbluh J, Chen S, Xiao Y, Shapiro GI, Hahn WC, Chin L. Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM. Proceedings of the National Academy of Sciences of the United States of America. 107: 11501-6. PMID 20534551 DOI: 10.1073/Pnas.1001613107 |
0.36 |
|
| 2010 |
Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MM, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, et al. Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. Plos One. 5: e10767. PMID 20532243 DOI: 10.1371/Journal.Pone.0010767 |
0.46 |
|
| 2010 |
Kabbarah O, Nogueira C, Feng B, Nazarian RM, Bosenberg M, Wu M, Scott KL, Kwong LN, Xiao Y, Cordon-Cardo C, Granter SR, Ramaswamy S, Golub T, Duncan LM, Wagner SN, ... ... Chin L, et al. Integrative genome comparison of primary and metastatic melanomas. Plos One. 5: e10770. PMID 20520718 DOI: 10.1371/Journal.Pone.0010770 |
0.319 |
|
| 2010 |
Zheng H, Ying H, Wiedemeyer R, Yan H, Quayle SN, Ivanova EV, Paik JH, Zhang H, Xiao Y, Perry SR, Hu J, Vinjamoori A, Gan B, Sahin E, Chheda MG, ... ... Chin L, et al. PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas. Cancer Cell. 17: 497-509. PMID 20478531 DOI: 10.1016/J.Ccr.2010.03.020 |
0.509 |
|
| 2010 |
Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, ... ... Chin L, ... ... Chin L, ... ... Chin L, ... ... Chin L, et al. International network of cancer genome projects. Nature. 464: 993-8. PMID 20393554 DOI: 10.1038/Nature08987 |
0.491 |
|
| 2010 |
Scott KL, Chin L. Signaling from the Golgi: mechanisms and models for Golgi phosphoprotein 3-mediated oncogenesis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 2229-34. PMID 20354134 DOI: 10.1158/1078-0432.CCR-09-1695 |
0.368 |
|
| 2010 |
Ying H, Zheng H, Scott K, Wiedemeyer R, Yan H, Lim C, Huang J, Dhakal S, Ivanova E, Xiao Y, Zhang H, Hu J, Stommel JM, Lee MA, Chen AJ, ... ... Chin L, et al. Mig-6 controls EGFR trafficking and suppresses gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6912-7. PMID 20351267 DOI: 10.1073/Pnas.0914930107 |
0.486 |
|
| 2010 |
Mukasa A, Wykosky J, Ligon KL, Chin L, Cavenee WK, Furnari F. Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence. Proceedings of the National Academy of Sciences of the United States of America. 107: 2616-21. PMID 20133782 DOI: 10.1073/Pnas.0914356107 |
0.308 |
|
| 2010 |
Zhou Y, Rideout WM, Zi T, Bressel A, Reddypalli S, Rancourt R, Woo JK, Horner JW, Chin L, Chiu MI, Bosenberg M, Jacks T, Clark SC, Depinho RA, Robinson MO, et al. Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas. Nature Biotechnology. 28: 71-8. PMID 20023657 DOI: 10.1038/Nbt.1595 |
0.534 |
|
| 2009 |
Paik JH, Ding Z, Narurkar R, Ramkissoon S, Muller F, Kamoun WS, Chae SS, Zheng H, Ying H, Mahoney J, Hiller D, Jiang S, Protopopov A, Wong WH, Chin L, et al. FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell. 5: 540-53. PMID 19896444 DOI: 10.1016/J.Stem.2009.09.013 |
0.468 |
|
| 2009 |
Scott KL, Kabbarah O, Liang MC, Ivanova E, Anagnostou V, Wu J, Dhakal S, Wu M, Chen S, Feinberg T, Huang J, Saci A, Widlund HR, Fisher DE, Xiao Y, ... ... Chin L, et al. GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer. Nature. 459: 1085-90. PMID 19553991 DOI: 10.1038/nature08109 |
0.376 |
|
| 2009 |
Kwong LN, Chin L. The metastasis problem gets stickier. Cancer Cell. 15: 1-2. PMID 19111873 DOI: 10.1016/J.Ccr.2008.12.007 |
0.318 |
|
| 2009 |
Paulson KG, Lemos BD, Feng B, Jaimes N, Peñas PF, Bi X, Maher E, Cohen L, Leonard JH, Granter SR, Chin L, Nghiem P. Array-CGH reveals recurrent genomic changes in Merkel cell carcinoma including amplification of L-Myc. The Journal of Investigative Dermatology. 129: 1547-55. PMID 19020549 DOI: 10.1038/jid.2008.365 |
0.344 |
|
| 2008 |
Gan B, Sahin E, Jiang S, Sanchez-Aguilera A, Scott KL, Chin L, Williams DA, Kwiatkowski DJ, DePinho RA. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization. Proceedings of the National Academy of Sciences of the United States of America. 105: 19384-9. PMID 19052232 DOI: 10.1073/Pnas.0810584105 |
0.488 |
|
| 2008 |
Kimmelman AC, Hezel AF, Aguirre AJ, Zheng H, Paik JH, Ying H, Chu GC, Zhang JX, Sahin E, Yeo G, Ponugoti A, Nabioullin R, Deroo S, Yang S, Wang X, ... ... Chin L, et al. Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. Proceedings of the National Academy of Sciences of the United States of America. 105: 19372-7. PMID 19050074 DOI: 10.1073/Pnas.0809966105 |
0.536 |
|
| 2008 |
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, ... ... Chin L, et al. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature. 455: 1129-33. PMID 18948956 DOI: 10.1038/Nature07443 |
0.516 |
|
| 2008 |
Stegh AH, Chin L, Louis DN, DePinho RA. What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator. Cell Cycle (Georgetown, Tex.). 7: 2833-9. PMID 18769159 DOI: 10.4161/Cc.7.18.6759 |
0.488 |
|
| 2008 |
Jeon HM, Jin X, Lee JS, Oh SY, Sohn YW, Park HJ, Joo KM, Park WY, Nam DH, DePinho RA, Chin L, Kim H. Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling. Genes & Development. 22: 2028-33. PMID 18676808 DOI: 10.1101/Gad.1668708 |
0.508 |
|
| 2008 |
Stegh AH, Kesari S, Mahoney JE, Jenq HT, Forloney KL, Protopopov A, Louis DN, Chin L, DePinho RA. Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 105: 10703-8. PMID 18669646 DOI: 10.1073/Pnas.0712034105 |
0.463 |
|
| 2008 |
Perera SA, Maser RS, Xia H, McNamara K, Protopopov A, Chen L, Hezel AF, Kim CF, Bronson RT, Castrillon DH, Chin L, Bardeesy N, Depinho RA, Wong KK. Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer. Carcinogenesis. 29: 747-53. PMID 18283039 DOI: 10.1093/Carcin/Bgn050 |
0.505 |
|
| 2007 |
Kwong L, Chin L, Wagner SN. Growth Factors and Oncogenes as Targets in Melanoma: Lost in Translation? Advances in Dermatology. 23: 99-129. PMID 18159898 DOI: 10.1016/J.Yadr.2007.07.015 |
0.334 |
|
| 2007 |
O'Neil J, Tchinda J, Gutierrez A, Moreau L, Maser RS, Wong KK, Li W, McKenna K, Liu XS, Feng B, Neuberg D, Silverman L, DeAngelo DJ, Kutok JL, Rothstein R, ... ... Chin L, et al. Alu elements mediate MYB gene tandem duplication in human T-ALL. The Journal of Experimental Medicine. 204: 3059-66. PMID 18070937 DOI: 10.1084/Jem.20071637 |
0.418 |
|
| 2007 |
Kim TK, Lee JS, Oh SY, Jin X, Choi YJ, Lee TH, Lee Eh, Choi YK, You S, Chung YG, Lee JB, DePinho RA, Chin L, Kim H. Direct transcriptional activation of promyelocytic leukemia protein by IFN regulatory factor 3 induces the p53-dependent growth inhibition of cancer cells. Cancer Research. 67: 11133-40. PMID 18056437 DOI: 10.1158/0008-5472.Can-07-1342 |
0.515 |
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| 2007 |
Martin ES, Tonon G, Sinha R, Xiao Y, Feng B, Kimmelman AC, Protopopov A, Ivanova E, Brennan C, Montgomery K, Kucherlapati R, Bailey G, Redston M, Chin L, DePinho RA. Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types. Cancer Research. 67: 10736-43. PMID 18006816 DOI: 10.1158/0008-5472.Can-07-2742 |
0.539 |
|
| 2007 |
Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, Chin L, DePinho RA, Cavenee WK. Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes & Development. 21: 2683-710. PMID 17974913 DOI: 10.1101/Gad.1596707 |
0.516 |
|
| 2007 |
Stommel JM, Kimmelman AC, Ying H, Nabioullin R, Ponugoti AH, Wiedemeyer R, Stegh AH, Bradner JE, Ligon KL, Brennan C, Chin L, DePinho RA. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science (New York, N.Y.). 318: 287-90. PMID 17872411 DOI: 10.1126/Science.1142946 |
0.491 |
|
| 2007 |
Maser RS, Choudhury B, Campbell PJ, Feng B, Wong KK, Protopopov A, O'Neil J, Gutierrez A, Ivanova E, Perna I, Lin E, Mani V, Jiang S, McNamara K, Zaghlul S, ... ... Chin L, et al. Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers. Nature. 447: 966-71. PMID 17515920 DOI: 10.1038/Nature05886 |
0.525 |
|
| 2007 |
Ji H, Wang Z, Perera SA, Li D, Liang MC, Zaghlul S, McNamara K, Chen L, Albert M, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Thomas RK, ... ... Chin L, et al. Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models. Cancer Research. 67: 4933-9. PMID 17510423 DOI: 10.1158/0008-5472.Can-06-4592 |
0.301 |
|
| 2007 |
Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, et al. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell. 128: 309-23. PMID 17254969 DOI: 10.1016/J.Cell.2006.12.029 |
0.56 |
|
| 2007 |
Stegh AH, Kim H, Bachoo RM, Forloney KL, Zhang J, Schulze H, Park K, Hannon GJ, Yuan J, Louis DN, DePinho RA, Chin L. Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma. Genes & Development. 21: 98-111. PMID 17210792 DOI: 10.1101/Gad.1480007 |
0.496 |
|
| 2006 |
Maher EA, Brennan C, Wen PY, Durso L, Ligon KL, Richardson A, Khatry D, Feng B, Sinha R, Louis DN, Quackenbush J, Black PM, Chin L, DePinho RA. Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities. Cancer Research. 66: 11502-13. PMID 17114236 DOI: 10.1158/0008-5472.Can-06-2072 |
0.497 |
|
| 2006 |
Liu F, Park PJ, Lai W, Maher E, Chakravarti A, Durso L, Jiang X, Yu Y, Brosius A, Thomas M, Chin L, Brennan C, DePinho RA, Kohane I, Carroll RS, et al. A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma. Cancer Research. 66: 10815-23. PMID 17090523 DOI: 10.1158/0008-5472.Can-06-1408 |
0.539 |
|
| 2006 |
Chin L, Garraway LA, Fisher DE. Malignant melanoma: genetics and therapeutics in the genomic era Genes & Development. 20: 2149-2182. PMID 16912270 DOI: 10.1101/Gad.1437206 |
0.332 |
|
| 2006 |
Kim M, Gans JD, Nogueira C, Wang A, Paik JH, Feng B, Brennan C, Hahn WC, Cordon-Cardo C, Wagner SN, Flotte TJ, Duncan LM, Granter SR, Chin L. Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell. 125: 1269-81. PMID 16814714 DOI: 10.1016/J.Cell.2006.06.008 |
0.336 |
|
| 2006 |
Bosenberg M, Muthusamy V, Curley DP, Wang Z, Hobbs C, Nelson B, Nogueira C, Horner JW, Depinho R, Chin L. Characterization of melanocyte-specific inducible Cre recombinase transgenic mice. Genesis (New York, N.Y. : 2000). 44: 262-7. PMID 16676322 DOI: 10.1002/Dvg.20205 |
0.455 |
|
| 2006 |
Carrasco DR, Tonon G, Huang Y, Zhang Y, Sinha R, Feng B, Stewart JP, Zhan F, Khatry D, Protopopova M, Protopopov A, Sukhdeo K, Hanamura I, Stephens O, Barlogie B, ... ... Chin L, et al. High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients. Cancer Cell. 9: 313-25. PMID 16616336 DOI: 10.1016/J.Ccr.2006.03.019 |
0.473 |
|
| 2006 |
Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 103: 5947-52. PMID 16585505 DOI: 10.1073/Pnas.0601273103 |
0.447 |
|
| 2006 |
Muthusamy V, Hobbs C, Nogueira C, Cordon-Cardo C, McKee PH, Chin L, Bosenberg MW. Amplification of CDK4 and MDM2 in malignant melanoma. Genes, Chromosomes & Cancer. 45: 447-54. PMID 16419059 DOI: 10.1002/Gcc.20310 |
0.325 |
|
| 2005 |
Seftor EA, Brown KM, Chin L, Kirschmann DA, Wheaton WW, Protopopov A, Feng B, Balagurunathan Y, Trent JM, Nickoloff BJ, Seftor RE, Hendrix MJ. Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment. Cancer Research. 65: 10164-9. PMID 16288000 DOI: 10.1158/0008-5472.Can-05-2497 |
0.325 |
|
| 2005 |
Tonon G, Wong KK, Maulik G, Brennan C, Feng B, Zhang Y, Khatry DB, Protopopov A, You MJ, Aguirre AJ, Martin ES, Yang Z, Ji H, Chin L, Depinho RA. High-resolution genomic profiles of human lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 102: 9625-30. PMID 15983384 DOI: 10.1073/Pnas.0504126102 |
0.529 |
|
| 2005 |
Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ. A genetic screen for candidate tumor suppressors identifies REST. Cell. 121: 837-48. PMID 15960972 DOI: 10.1016/J.Cell.2005.03.033 |
0.578 |
|
| 2004 |
Blelloch RH, Hochedlinger K, Yamada Y, Brennan C, Kim M, Mintz B, Chin L, Jaenisch R. Nuclear cloning of embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 13985-90. PMID 15306687 DOI: 10.1073/Pnas.0405015101 |
0.308 |
|
| 2004 |
Hochedlinger K, Blelloch R, Brennan C, Yamada Y, Kim M, Chin L, Jaenisch R. Reprogramming of a melanoma genome by nuclear transplantation. Genes & Development. 18: 1875-85. PMID 15289459 DOI: 10.1101/Gad.1213504 |
0.355 |
|
| 2004 |
Brennan C, Zhang Y, Leo C, Feng B, Cauwels C, Aguirre AJ, Kim M, Protopopov A, Chin L. High-resolution global profiling of genomic alterations with long oligonucleotide microarray. Cancer Research. 64: 4744-8. PMID 15256441 DOI: 10.1158/0008-5472.CAN-04-1241 |
0.337 |
|
| 2004 |
Aguirre AJ, Brennan C, Bailey G, Sinha R, Feng B, Leo C, Zhang Y, Zhang J, Gans JD, Bardeesy N, Cauwels C, Cordon-Cardo C, Redston MS, DePinho RA, Chin L. High-resolution characterization of the pancreatic adenocarcinoma genome. Proceedings of the National Academy of Sciences of the United States of America. 101: 9067-72. PMID 15199222 DOI: 10.1073/Pnas.0402932101 |
0.532 |
|
| 2003 |
O'Hagan RC, Brennan CW, Strahs A, Zhang X, Kannan K, Donovan M, Cauwels C, Sharpless NE, Wong WH, Chin L. Array comparative genome hybridization for tumor classification and gene discovery in mouse models of malignant melanoma. Cancer Research. 63: 5352-6. PMID 14500367 |
0.354 |
|
| 2003 |
Sharpless NE, Kannan K, Xu J, Bosenberg MW, Chin L. Both products of the mouse INK4a/ARF locus suppress melanoma formation in vivo Oncogene. 22: 5055-5059. PMID 12902988 DOI: 10.1038/Sj.Onc.1206809 |
0.307 |
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| 2003 |
Sharpless NE, Chin L. The INK4α/ARF locus and melanoma Oncogene. 22: 3092-3098. PMID 12789286 DOI: 10.1038/Sj.Onc.1206461 |
0.322 |
|
| 2002 |
O'Hagan RC, Chang S, Maser RS, Mohan R, Artandi SE, Chin L, DePinho RA. Telomere dysfunction provokes regional amplification and deletion in cancer genomes. Cancer Cell. 2: 149-55. PMID 12204535 DOI: 10.1016/S1535-6108(02)00094-6 |
0.537 |
|
| 2002 |
Sviderskaya EV, Hill SP, Evans-Whipp TJ, Chin L, Orlow SJ, Easty DJ, Cheong SC, Beach D, DePinho RA, Bennett DC. p16(Ink4a) in melanocyte senescence and differentiation. Journal of the National Cancer Institute. 94: 446-54. PMID 11904317 DOI: 10.1093/Jnci/94.6.446 |
0.488 |
|
| 2002 |
You MJ, Castrillon DH, Bastian BC, O'Hagan RC, Bosenberg MW, Parsons R, Chin L, DePinho RA. Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 1455-60. PMID 11818530 DOI: 10.1073/Pnas.022632099 |
0.552 |
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