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Robert H. Bates - Publications

Affiliations: 
2009 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wilson C, Ray P, Zuccotto F, Hernandez J, Aggarwal A, Mackenzie C, Caldwell N, Taylor M, Huggett M, Mathieson M, Murugesan D, Smith A, Davis S, Cocco M, Parai MK, ... ... Bates RH, et al. Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target. Journal of Medicinal Chemistry. PMID 34910486 DOI: 10.1021/acs.jmedchem.1c01586  0.302
2020 Balabon O, Pitta E, Rogacki MK, Meiler E, Casanueva R, Guijarro L, Huss S, Lopez-Roman EM, Santos-Villarejo Á, Augustyns K, Ballell L, Aguirre DB, Bates RH, Cunningham F, Cacho M, et al. Optimization of Hydantoins as Potent Antimycobacterial Decaprenylphosphoryl-β-d-Ribose Oxidase (DprE1) Inhibitors. Journal of Medicinal Chemistry. PMID 32342688 DOI: 10.1021/Acs.Jmedchem.0C00107  0.386
2020 Cunningham F, Esquivias J, Fernández-Menéndez R, Pérez A, Guardia A, Escribano J, Rivero C, Vimal M, Cacho M, de Dios-Antón P, Martínez-Martínez MS, Jiménez E, Huertas Valentín L, Rebollo-López MJ, López-Román EM, ... ... Bates RH, et al. Exploring the SAR of the β-Ketoacyl-ACP Synthase Inhibitor GSK3011724A and Optimization around a Genotoxic Metabolite. Acs Infectious Diseases. PMID 32196311 DOI: 10.1021/Acsinfecdis.9B00493  0.317
2019 Poce G, Consalvi S, Venditti G, Alfonso S, Desideri N, Fernandez-Menendez R, Bates RH, Ballell L, Barros Aguirre D, Rullas J, De Logu A, Gardner M, Ioerger TR, Rubin EJ, Biava M. Novel Pyrazole-Containing Compounds Active against . Acs Medicinal Chemistry Letters. 10: 1423-1429. PMID 31620228 DOI: 10.1021/Acsmedchemlett.9B00204  0.356
2018 Rogacki MK, Pitta E, Balabon OB, Huss S, Lopez-Roman EM, Argyrou A, Blanco-Ruano D, Cacho M, Vande Velde CML, Augustyns K, Ballell L, Barros D, Bates R, Cunningham F, Van der Veken P. Identification and profiling of hydantoins - a novel class of potent antimycobacterial DprE1 inhibitors. Journal of Medicinal Chemistry. PMID 30500189 DOI: 10.1021/Acs.Jmedchem.8B01356  0.405
2018 Fang C, Lee KK, Nietupski R, Bates RH, Fernandez-Menendez R, Lopez-Roman EM, Guijarro-Lopez L, Yin Y, Peng Z, Gomez JE, Fisher S, Barros-Aguirre D, Hubbard BK, Serrano-Wu MH, Hung DT. Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 30316633 DOI: 10.1016/J.Bmcl.2018.09.037  0.368
2018 Richter A, Rudolph I, Möllmann U, Voigt K, Chung CW, Singh OMP, Rees M, Mendoza-Losana A, Bates R, Ballell L, Batt S, Veerapen N, Fütterer K, Besra G, Imming P, et al. Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1. Scientific Reports. 8: 13473. PMID 30194385 DOI: 10.1038/S41598-018-31316-6  0.353
2018 Prati F, Zuccotto F, Fletcher D, Convery MA, Fernandez-Menendez R, Bates R, Encinas L, Zeng J, Chung CW, De Dios Anton P, Mendoza-Losana A, Mackenzie C, Green SR, Huggett M, Barros D, et al. Screening of a novel fragment library with functional complexity against Mycobacterium tuberculosis InhA. Chemmedchem. PMID 29399991 DOI: 10.1002/Cmdc.201700774  0.344
2017 Poce G, Cocozza M, Alfonso S, Consalvi S, Venditti G, Fernandez-Menendez R, Bates RH, Barros Aguirre D, Ballell L, De Logu A, Vistoli G, Biava M. In vivo potent BM635 analogue with improved drug-like properties. European Journal of Medicinal Chemistry. 145: 539-550. PMID 29335214 DOI: 10.1016/J.Ejmech.2017.12.075  0.397
2017 Machutta CA, Kollmann CS, Lind KE, Bai X, Chan PF, Huang J, Ballell L, Belyanskaya S, Besra GS, Barros-Aguirre D, Bates RH, Centrella PA, Chang SS, Chai J, Choudhry AE, et al. Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening. Nature Communications. 8: 16081. PMID 28714473 DOI: 10.1038/Ncomms16081  0.354
2016 Pitta E, Balabon O, Rogacki MK, Gómez J, Cunningham F, Joosens J, Augustyns K, van der Veken P, Bates R. Differential characterization using readily accessible NMR experiments of novel N- and O-alkylated quinolin-4-ol, 1,5-naphthyridin-4-ol and quinazolin-4-ol derivatives with antimycobacterial activity. European Journal of Medicinal Chemistry. 125: 890-901. PMID 27769030 DOI: 10.1016/J.Ejmech.2016.10.014  0.336
2016 Abrahams KA, Chung CW, Ghidelli-Disse S, Rullas J, Rebollo-López MJ, Gurcha SS, Cox JA, Mendoza A, Jiménez-Navarro E, Martínez-Martínez MS, Neu M, Shillings A, Homes P, Argyrou A, Casanueva R, ... ... Bates RH, et al. Identification of KasA as the cellular target of an anti-tubercular scaffold. Nature Communications. 7: 12581. PMID 27581223 DOI: 10.1038/Ncomms12581  0.375
2016 Pitta E, Rogacki MK, Balabon O, Huss S, Cunningham F, Lopez-Roman EM, Joossens J, Augustyns K, Ballell L, Bates RH, Van der Veken P. Searching for new leads for Tuberculosis: Design, synthesis and biological evaluation of novel 2-quinolin-4-yloxyacetamides. Journal of Medicinal Chemistry. PMID 27348630 DOI: 10.1021/Acs.Jmedchem.6B00245  0.388
2015 Rebollo-Lopez MJ, Lelièvre J, Alvarez-Gomez D, Castro-Pichel J, Martínez-Jiménez F, Papadatos G, Kumar V, Colmenarejo G, Mugumbate G, Hurle M, Barroso V, Young RJ, Martinez-Hoyos M, González Del Río R, Bates RH, et al. Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery. Plos One. 10: e0142293. PMID 26642067 DOI: 10.1371/Journal.Pone.0142293  0.383
2015 Simal C, Bates RH, Ureña M, Giménez I, Koutsou C, Infantes L, Fernández de la Pradilla R, Viso A. Synthesis of Enantiopure 3-Hydroxypiperidines from Sulfinyl Dienyl Amines by Diastereoselective Intramolecular Cyclization and [2,3]-Sigmatropic Rearrangement. The Journal of Organic Chemistry. 80: 7674-92. PMID 26162504 DOI: 10.1021/Acs.Joc.5B01307  0.323
2015 Ordas A, Raterink RJ, Cunningham F, Jansen HJ, Wiweger MI, Jong-Raadsen S, Bos S, Bates RH, Barros D, Meijer AH, Vreeken RJ, Ballell-Pages L, Dirks RP, Hankemeier T, Spaink HP. Testing tuberculosis drug efficacy in a zebrafish high-throughput translational medicine screen. Antimicrobial Agents and Chemotherapy. 59: 753-62. PMID 25385118 DOI: 10.1128/Aac.03588-14  0.352
2013 Poce G, Bates RH, Alfonso S, Cocozza M, Porretta GC, Ballell L, Rullas J, Ortega F, De Logu A, Agus E, La Rosa V, Pasca MR, De Rossi E, Wae B, Franzblau SG, et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. Plos One. 8: e56980. PMID 23437287 DOI: 10.1371/Journal.Pone.0056980  0.415
2013 Ballell L, Bates RH, Young RJ, Alvarez-Gomez D, Alvarez-Ruiz E, Barroso V, Blanco D, Crespo B, Escribano J, González R, Lozano S, Huss S, Santos-Villarejo A, Martín-Plaza JJ, Mendoza A, et al. Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis. Chemmedchem. 8: 313-21. PMID 23307663 DOI: 10.1002/Cmdc.201200428  0.366
2008 Bates RH, Chen M, Roush WR. Applications of chiral allylmetallating agents toward the synthesis of oxygen heterocyles. Current Opinion in Drug Discovery & Development. 11: 778-92. PMID 18946843  0.378
2008 Bates RH, Shotwell JB, Roush WR. Stereoselective syntheses of the C(1)-C(9) fragment of amphidinolide C. Organic Letters. 10: 4343-6. PMID 18783230 DOI: 10.1021/Ol801852J  0.395
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